isoproterenol has been researched along with cpu0213 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, DZ; Dai, Y; Feng, Y; Tang, XY | 1 |
| Dai, DZ; Dai, Y; Luo, L | 1 |
| Dai, DZ; Dai, Y; Ji, H; Tang, XY; Xu, M | 1 |
| Dai, DZ; Dai, Y; Li, N; Xu, J; Yu, F | 1 |
| Cheng, YS; Dai, DZ; Dai, Y | 3 |
| Dai, DZ; Dai, Y; Hu, C; Jia, N; Li, N | 1 |
8 other study(ies) available for isoproterenol and cpu0213
| Article | Year |
|---|---|
Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors.
Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Cells, Cultured; Down-Regulation; Endothelin Receptor Antagonists; Heart; Heart Failure; Isoproterenol; Male; Myocytes, Cardiac; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tacrolimus Binding Proteins; Ventricular Fibrillation | 2007 |
Effect of the endothelin receptor antagonist CPU0213, and its modulation by rifampin, on cardiac and vascular tissue following chronic isoproterenol treatment.
Topics: Animals; Aorta, Thoracic; Endothelin Receptor Antagonists; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Rifampin | 2008 |
Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats.
Topics: Animals; Calcineurin; Cardiotonic Agents; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Heart Failure; Isoproterenol; Leptin; Male; Propranolol; Pyrazoles; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2008 |
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature.
Topics: Animals; Aorta, Thoracic; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Guanidines; In Vitro Techniques; Isoproterenol; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Up-Regulation | 2008 |
Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin.
Topics: Animals; Cardiomegaly; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Down-Regulation; Endothelin Receptor Antagonists; Erythromycin; Heart Failure; Hemodynamics; Isoproterenol; Leptin; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus Binding Proteins; Up-Regulation | 2009 |
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.
Topics: Animals; Cardiotonic Agents; Endothelin Receptor Antagonists; Gene Expression Regulation; Guanidines; Heart; Hypertrophy; Isoproterenol; Male; Matrix Metalloproteinase 9; Myocardium; NADPH Oxidases; Nitric Oxide Synthase; Protein Kinase C-epsilon; Pyrazoles; Rats; Rats, Sprague-Dawley | 2009 |
Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Cvarepsilon and is attenuated by an endothelin receptor antagonist CPU0213.
Topics: Adrenergic beta-Antagonists; Animals; Blotting, Western; Drug Therapy, Combination; Follicle Stimulating Hormone; Gene Expression; Injections, Subcutaneous; Isoproterenol; Leptin; Male; Phosphorylation; Protein Kinase C-epsilon; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminiferous Tubules; Testis; Testosterone; Up-Regulation | 2010 |
Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart.
Topics: Animals; Arrhythmias, Cardiac; Blotting, Western; Calcium-Binding Proteins; Cells, Cultured; Down-Regulation; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; Isoproterenol; Male; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Pyrazoles; Rats; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological | 2010 |