isoproterenol and cpu0213

isoproterenol has been researched along with cpu0213 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dai, DZ; Dai, Y; Feng, Y; Tang, XY1
Dai, DZ; Dai, Y; Luo, L1
Dai, DZ; Dai, Y; Ji, H; Tang, XY; Xu, M1
Dai, DZ; Dai, Y; Li, N; Xu, J; Yu, F1
Cheng, YS; Dai, DZ; Dai, Y3
Dai, DZ; Dai, Y; Hu, C; Jia, N; Li, N1

Other Studies

8 other study(ies) available for isoproterenol and cpu0213

ArticleYear
Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Cells, Cultured; Down-Regulation; Endothelin Receptor Antagonists; Heart; Heart Failure; Isoproterenol; Male; Myocytes, Cardiac; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tacrolimus Binding Proteins; Ventricular Fibrillation

2007
Effect of the endothelin receptor antagonist CPU0213, and its modulation by rifampin, on cardiac and vascular tissue following chronic isoproterenol treatment.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:7

    Topics: Animals; Aorta, Thoracic; Endothelin Receptor Antagonists; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Rifampin

2008
Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:6

    Topics: Animals; Calcineurin; Cardiotonic Agents; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Heart Failure; Isoproterenol; Leptin; Male; Propranolol; Pyrazoles; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2008
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:1

    Topics: Animals; Aorta, Thoracic; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Guanidines; In Vitro Techniques; Isoproterenol; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Up-Regulation

2008
Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:5

    Topics: Animals; Cardiomegaly; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Down-Regulation; Endothelin Receptor Antagonists; Erythromycin; Heart Failure; Hemodynamics; Isoproterenol; Leptin; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus Binding Proteins; Up-Regulation

2009
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:8

    Topics: Animals; Cardiotonic Agents; Endothelin Receptor Antagonists; Gene Expression Regulation; Guanidines; Heart; Hypertrophy; Isoproterenol; Male; Matrix Metalloproteinase 9; Myocardium; NADPH Oxidases; Nitric Oxide Synthase; Protein Kinase C-epsilon; Pyrazoles; Rats; Rats, Sprague-Dawley

2009
Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Cvarepsilon and is attenuated by an endothelin receptor antagonist CPU0213.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Blotting, Western; Drug Therapy, Combination; Follicle Stimulating Hormone; Gene Expression; Injections, Subcutaneous; Isoproterenol; Leptin; Male; Phosphorylation; Protein Kinase C-epsilon; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminiferous Tubules; Testis; Testosterone; Up-Regulation

2010
Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:5-6

    Topics: Animals; Arrhythmias, Cardiac; Blotting, Western; Calcium-Binding Proteins; Cells, Cultured; Down-Regulation; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; Isoproterenol; Male; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Pyrazoles; Rats; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological

2010