isoproterenol has been researched along with colforsin in 1593 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 410 (25.74) | 18.7374 |
| 1990's | 811 (50.91) | 18.2507 |
| 2000's | 299 (18.77) | 29.6817 |
| 2010's | 69 (4.33) | 24.3611 |
| 2020's | 4 (0.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kajimoto, N; Nishimura, Y; Suzuki, A; Usui, H; Yamanishi, Y | 1 |
| Opie, LH; Worthington, MG | 1 |
| Noma, A; Ono, K; Tareen, FM; Yoshida, A | 1 |
| Azuma, H; Oshima, H; Tsujii, T; Yamaguchi, T | 1 |
| Kamei, C; Mukai, T; Tasaka, K | 1 |
| Botella, A; Bueno, L; Delvaux, M; Frexinos, J | 1 |
| Joyner, RW; Osaka, T | 1 |
| Lee, H; Matsuda, JJ; Shibata, EF | 1 |
| Colbran, JL; Corbin, JD; Francis, SH; Jiang, H | 1 |
| De Blasi, A; Finardi, G; Fratelli, M; Fratino, P; Melzi d'Eril, G; Negri, F | 1 |
| Dunwiddie, TV; Heginbotham, LR; Proctor, WR; Taylor, M | 1 |
| Barnard, J; Haynes, J; Seibert, AF; Taylor, A; Thompson, WJ; Wilborn, WH | 1 |
| Mader, SL | 1 |
| Abe, S; Ishizuka, J; Murakami, M; Satoh, Y; Shintani, S; Suzuki, K; Suzuki, S; Thompson, JC; Toyota, T | 1 |
| Bradley, ME; Buxton, IL; Keef, KD; Zhang, L | 1 |
| Amiel, C; Friedlander, G; Herman, P; Huy, PT | 1 |
| Adkins, WK; Barnard, JW; Haynes, J; May, S; Seibert, AF; Taylor, AE | 1 |
| Kamata, K; Kasuya, Y; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Feth, F; Michel, MC; Rascher, W | 1 |
| Kuhne, W; Piper, HM; Schwartz, P; Watanabe, H | 1 |
| Birnbaumer, L; Birnbaumer, M; Gudermann, T; Levy, FO; Nichols, C | 1 |
| Abdel-Latif, AA; Akhtar, RA; Tachado, SD; Zhou, CJ | 1 |
| Borst, SE; Crass, MF; Scarpace, PJ | 1 |
| Heindel, JJ; Treinen, KA | 1 |
| Ailhaud, G; Gaillard, D; Négrel, R; Vassaux, G | 1 |
| Devlin, AM; Leckie, BJ | 2 |
| Blennerhassett, MG; Garfield, RE; Sakai, N | 1 |
| Newsholme, SJ; Torphy, TJ; Zhou, HL | 1 |
| Eriksson, PS; Hansson, E; Rönnbäck, L | 1 |
| Itoh, T; Kuriyama, H; Shafiq, J; Suzuki, S | 1 |
| Mészáros, J | 1 |
| Lévai, G; Mészáros, J | 1 |
| Ishac, EJ; Kunos, G; Lazar-Wesley, E | 1 |
| Aripova, NA; Krasnikova, TL; Parfyonova, EV; Yurenev, AP | 1 |
| Aiyar, N; Edwards, RM; Hofmann, GA; Mattern, MR; Nambi, P | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 3 |
| Salomon, Y; Zohar, M | 1 |
| Lin, W; McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Ehlert, FJ; Griffin, MT | 1 |
| Kondratiuk, TP; Kurskiĭ, MD; Nikolenko, LM; Prishchepa, LA; Vladimirova, IA | 1 |
| Biser, PS; Fleming, WW; Roberts, MI; Stadel, JM; Taylor, DA | 1 |
| Graier, WF; Groschner, K; Kukovetz, WR; Schmidt, K | 1 |
| Campbell, WB; Farrar, MA; Magness, RR; Shaul, PW | 1 |
| Lew, DB; Malik, KU; Nadel, GL | 1 |
| Ann, DK; Lin, HH | 1 |
| Gray, DW; Marshall, I | 1 |
| Hirota, A | 1 |
| Garg, LC; Mohuczy-Dominiak, D | 1 |
| Del Monte, F; Harding, SE; Jones, SM; Poole-Wilson, PA; Vescovo, G | 1 |
| Droms, KA; Lange-Carter, CA; Malkinson, AM; Vuillequez, JJ | 1 |
| Bian, XP; Seidler, FJ; Slotkin, TA | 2 |
| Ando, M; Kihara, K; Kondo, S; Morita, T; Oshima, H; Tashima, Y | 1 |
| Guo, H; Rosenthal, JE; Wasserstrom, JA | 1 |
| Ayajiki, K; Toda, N | 1 |
| Atkinson, BN; Minneman, KP | 3 |
| Dieudonne, MN; Giudicelli, Y; Pecquery, R | 1 |
| Keith, C; Reinach, PS; Scanlon, M; Socci, RR | 1 |
| Arilla, E; Colás, B; Prieto, JP | 1 |
| Iga, T; Maeno, N | 1 |
| Adler, M; Filbert, MG; Moore, DH | 1 |
| Batticane, N; Gallo, F; Marchetti, B; Morale, MC | 1 |
| Joseph, S; MacDermot, J; McEwan, JR; Parsaee, H | 1 |
| Bitran, JA; Chen, G; Gusovsky, F; Manji, HK; Potter, WZ | 1 |
| Brooker, G; DeBernardi, MA | 1 |
| Hanke, K; Möller, K; Perrin, D; Söling, HD | 1 |
| Harbon, S; Khac, LD; Mokhtari, A; Renner, M | 1 |
| Furuyama, S; Hara-Yokoyama, M; Sugiya, H | 1 |
| Gadsby, DC; Horie, M; Hwang, TC; Nairn, AC | 1 |
| Kanoh, M; Konat, G; Laszkiewicz, I; Royland, JE; Wiggins, RC; Ye, P; Zhu, W | 1 |
| Fischer, MJ; Janssen, LH; Nijkamp, FP; van Oosterhout, AJ | 1 |
| Pahapill, PA; Schlichter, LC | 1 |
| Hosono, M; Ishizuka, O; Nakamura, K | 1 |
| Camden, JM; Turner, JT | 1 |
| Broadley, KJ; Urquhart, RA | 2 |
| Bishopric, NH; Sato, B; Webster, KA | 1 |
| Bressler, JP; Brightman, MW; Tao-Cheng, JH | 1 |
| MacLeod, KM; Ray, A | 2 |
| Daykin, K; Hall, IP; Townsend, P; Widdop, S | 1 |
| Keenan, AK; Kent, A; Redmond, EM | 1 |
| Chen, J; Iyengar, R; Ma, HW; Ponnapalli, M; Premont, RT | 1 |
| Houslay, MD; Palmer, TM; Taberner, PV | 1 |
| Busija, DW; Chen, J | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L | 1 |
| Belardinelli, L; Lerman, BB; Song, Y; Thedford, S | 1 |
| Das, B; Fricker, LD; Klein, RS | 1 |
| Bangert, M; Beyer, T; Niroomand, F; Rauch, B | 1 |
| Duff, HJ; Hill, RJ; Sheldon, RS; Taouis, M | 1 |
| Gross, R; Hillaire-Buys, D; Loubatières-Mariani, MM; Ribes, G | 1 |
| Berry, JL; Boyle, JP; Chapman, ID; Elliott, KR; Foster, RW; Small, RC; Watt, AJ | 1 |
| Chin, JH; Hoffman, BB | 2 |
| Bitran, JA; Chen, GA; Gusovsky, F; Manji, HK; Potter, WZ | 1 |
| Couraud, PO; Durieu-Trautmann, O; Glibert, F; Marin, P; Nguyen, DL; Strosberg, AD | 1 |
| Bouvier, M; Calderone, A; de Champlain, J; Juneau, C; Li, K; Rouleau, JL | 1 |
| Alousi, AA; Insel, PA; Jasper, JR; Motulsky, HJ | 1 |
| Nalepa, I; Vetulani, J | 2 |
| Boucher, RC; Cheng, EH; Paradiso, AM | 1 |
| Kilfeather, SA; O'Malley, K; Stein, M | 1 |
| Calderone, A; de Champlain, J; Rouleau, JL | 1 |
| Brodde, OE; Maisel, AS; Michel, MC; Motulsky, HJ; van Tits, LJ | 1 |
| Hartzell, HC; Lagrutta, A; Parsons, TD; White, RE | 1 |
| Abe, K; Igarashi, Y; Kondo, Y; Kudo, K; Tada, K; Yoshinaga, K | 1 |
| Ardaillou, N; Ardaillou, R; Blanchard, A; Savic, V; Stefanovic, V; Vlahovic, P | 1 |
| Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S | 1 |
| Emmerich, B; Göhly, U; Haen, E; Hallek, M; Kamp, T; Remien, J | 1 |
| Kudlacz, EM; Navarro, HA; Slotkin, TA | 1 |
| Rajakumar, G; Scarpace, PJ | 2 |
| Kishi, M; Kuriyama, K; Ma, FH; Ohkuma, S | 1 |
| Bast, A; Van der Vliet, A | 1 |
| De Pergola, G; Giorgino, R | 1 |
| Couraud, PO; Durieu-Trautmann, O; Foignant-Chaverot, N; Strosberg, AD | 1 |
| Buchan, KW; Martin, W | 1 |
| Chidiac, P; Nagy, A; Sole, MJ; Wells, JW | 1 |
| Roberts, JM; Russell, JA | 1 |
| Buja, LM; Farrar, MA; Shaul, PW | 1 |
| Pracyk, JB; Slotkin, TA | 1 |
| Fleming, WW; Taylor, DA | 1 |
| Taylor, AE | 1 |
| Ono, K; Trautwein, W | 1 |
| Carlebach, R; Lemmer, B; Nitsch, R; Ohm, TG; Stiller, M | 1 |
| Mori-Okamoto, J; Namii, Y; Tatsuno, J | 1 |
| Foster, KA; Hock, CE; Reibel, DK | 1 |
| Fujinami, H; Izawa, T; Komabayshi, T; Nakamura, T; Suda, K; Tsuboi, M | 1 |
| Hansson, E; Rönnbäck, L | 1 |
| Bouanani, N; Corsin, A; Crozatier, B; Gilson, N | 1 |
| Amiel, C; Bernard, C; Ferrary, E; Friedlander, G; Sterkers, O | 1 |
| Inoue, H; Okabe, K; Osa, T | 1 |
| Reisine, T; White, MM | 1 |
| Cohen, P; Hardie, DG; Haystead, TA; Moore, F | 1 |
| Johnson, RA; Toews, ML | 1 |
| Fujimoto, S; Matsuda, T | 1 |
| Boege, F; Cantrill, RC; Hahn, M; Heithier, H; Kurstjens, NP | 1 |
| Lugnier, C; Muller, B; Stoclet, JC | 1 |
| Ball, RL; Carpenter, G; Tanner, KD | 1 |
| Björntorp, P; De Pergola, G; Giorgino, R; Holmäng, A; Svedberg, J | 1 |
| Fukumitsu, T; Hayashi, H; Tokuno, H; Tomita, T | 1 |
| Canalis, E; Centrella, M; McCarthy, TL | 1 |
| Kasper, G; Marquez, CR; Zatz, M | 1 |
| Greenfield, LJ; Hackett, JT; Linden, J | 1 |
| Harvath, L; Robbins, JD; Russell, AA; Seamon, KB | 1 |
| Chabardès, D; Montégut, M; Siaume-Perez, S; Zhou, Y | 1 |
| Bowling, N; Gengo, PJ; Hayes, JS; Kauffman, RF; Utterback, B; Wyss, VL | 1 |
| Chaudhari, A; Gupta, S; Kirschenbaum, MA | 1 |
| Chihara, T; Nomura, Y; Tokumitsu, Y; Uehara, T | 1 |
| Lory, P; Nargeot, J; Nerbonne, JM; Richard, S; Tiaho, F | 1 |
| Flores-Riveros, JR; Janicot, M; Kaestner, KH; Lane, MD; McLenithan, JC | 1 |
| Lynch, C | 1 |
| Watkins, WD; Whorton, AR; Xuan, YT | 1 |
| Arneson-Rotert, LJ; Hoffman, JM; Johnson, RA; Toews, ML | 1 |
| Dubyak, GR; Jones, SW; Marks, TN | 1 |
| Berger, HJ; Pfeifer, A; Rupp, H; Werdan, K | 1 |
| De Mey, JG; Heesen, BJ | 1 |
| Kohno, S; Matsubayashi, H; Tsuru, H | 1 |
| Buja, LM; DeBeltz, D; Muntz, KH; Shaul, PW | 1 |
| Langeler, EG; van Hinsbergh, VW | 1 |
| Enero, MA; Kazanietz, MG | 1 |
| De Mello, WC; Xiao, RP | 1 |
| Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Harvey, RD; Hume, JR; Jurevicius, JA | 1 |
| Dehaye, JP; Turner, RJ | 1 |
| Clark, WA; Decker, RS; LaPres, JJ; Lesch, M; Rudnick, SJ | 1 |
| Andersson, KE; Lindgren, S | 1 |
| Barbry, P; Champigny, G; Chastre, E; Di Gioia, Y; Emami, S; Fanen, P; Gespach, C; Mornet, E; Simon-Bouy, B | 1 |
| Chao, AC; Katayama, Y | 1 |
| Fong, JC; Hong, PK; Leu, SJ | 1 |
| Batter, DK; Kessler, JA | 1 |
| Hescheler, J; Wallukat, G; Wobus, AM | 1 |
| Sperelakis, N; Tripathi, O | 1 |
| Chneiweiss, H; Cordier, J; Sobel, A | 1 |
| Silverman, PB; Steketee, JD; Swann, AC | 1 |
| Chang, F; Cohen, IS; DiFrancesco, D; Rosen, MR; Tromba, C | 1 |
| Demarne, Y; Lecourtier, MJ; Lhuillery, C; Nicolas, C | 1 |
| Kedem, J; Mackenzie, JW; Rodriquez, E; Scholz, PM; Weiss, HR; Wong, J; Wright, CC | 1 |
| Brown, LA | 1 |
| Iizuka, K; Nakazawa, T; Yoshie, Y | 1 |
| Bonin, H; Bouvier, M; Guilbault, N | 1 |
| Hayashi, M; Iyori, M; Kitajima, W; Saruta, T; Yamaji, Y | 1 |
| Austin, CE; Chess-Williams, R | 1 |
| Beusenberg, FD; Bonta, IL; Leurs, R; van Amsterdam, JG; van Schaik, A | 1 |
| Houslay, MD; Palmer, TM | 1 |
| Fujita, M; Hanai, H; Matsunaga, T; Natsukari, N | 1 |
| Bertrand, F; Capeau, J; Cherqui, G; Garcia, I; Hermelin, B; Paul, A; Picard, J | 1 |
| Del Monte, F; Harding, SE; Hunt, NA; Jones, SM | 1 |
| Dahlman, D; MacLeod, KM; McKinley, JB | 1 |
| Kavlock, RJ; Kudlacz, EM; Navarro, HA; Slotkin, TA | 1 |
| Korichneva, IL; Tkachuk, VA | 1 |
| Gierschik, P; Jakobs, KH; Müller, U; Reithmann, C; Werdan, K | 1 |
| Bausher, LP; Horio, B | 2 |
| Hildebrandt, JD; Kohnken, RE | 1 |
| Mayer, H; Rupp, E; Wingender, E | 1 |
| Nikinmaa, M; Salama, A | 1 |
| Bast, A; Haenen, GR; Veerman, M | 1 |
| Briggs, GM; Callahan, M; Copelas, L; Feldman, MD; Grossman, W; Gwathmey, JK; Morgan, JP; Phillips, PJ; Schoen, FJ; Warren, SE | 1 |
| Bohl, J; Lemmer, B; Ohm, TG | 2 |
| Abrahamsen, J; Nedergaard, OA | 1 |
| Beauville, M; Berlan, M; Crampes, F; Lafontan, M; Montastruc, JL; Valet, P | 1 |
| Ciaranello, RD; Dean, R; Tan, GL | 1 |
| Milligan, G; Nair, BG; Parikh, B; Patel, TB | 1 |
| Setchenska, MS; Timanova, AM | 1 |
| Björntorp, P; De Pergola, G; Xu, X | 1 |
| Barsony, J; Marx, SJ | 1 |
| Buckenmeyer, PJ; Dax, EM; Goldfarb, AH; Partilla, JS; Piñeyro, MA | 1 |
| Grider, JR | 1 |
| Abe, K; Matsuki, N; Nagata, K; Saito, H; Wang, CH | 1 |
| Houslay, MD; Milligan, G; Strassheim, D | 1 |
| Brown, EM; el-Hajj Fuleihan, G | 1 |
| Bressler, JP; Tinsely, P | 1 |
| Diamond, J; Giembycz, MA | 1 |
| Carlson, DM; Lenney, C; Wright, PS | 1 |
| Buzzell, GR; Menendez-Pelaez, A; Nonaka, KO; Reiter, RJ | 1 |
| Cignarelli, M; Corso, M; De Pergola, G; Di Paolo, S; Garruti, G; Giorgino, R | 1 |
| Dickinson, KE; Hirschowitz, BI; Horiguchi, Y; Matsumoto, H; Uemura, N | 1 |
| Blackshear, PJ; Lobaugh, LA | 1 |
| Cepelík, J; Hynie, S | 3 |
| Kameyama, M; Yazawa, K | 1 |
| Ballieux, RE; Heijnen, CJ; Kavelaars, A | 1 |
| Burton, MD; Johnson, DC; Kazemi, H | 1 |
| Bonin, H; Bouvier, M; Caron, MG; Hnatowich, M; Lefkowitz, RJ; Valiquette, M | 1 |
| Fishman, PH; Gordon, EA; Kohout, TA | 1 |
| Shigenobu, K; Tanaka, H | 1 |
| Bailey, IA; Kemp, PR; Radda, GK; Seymour, AM | 1 |
| Hui, KK; Yu, JL | 3 |
| Hesslinger, B; McDonald, TF; Pelzer, D; Shuba, YM; Trautwein, W | 1 |
| Aiyar, N; Crooke, ST; Nambi, P | 1 |
| Chao, W; Hanahan, DJ; Liu, HL; Olson, MS; Zhou, WG | 1 |
| Stuart-Smith, K; Vanhoutte, PM | 1 |
| Grojec, MS; Ishac, EJ; Kapocsi, J; Kunos, G | 1 |
| McCook, EC; Navarro, HA; Seidler, FJ; Slotkin, TA | 1 |
| Mishler, K; Schwartz, JP | 1 |
| Baudysová, M; Houstĕk, J; Kopecký, J; Pavelka, S | 1 |
| Dodson, WC; Heindel, JJ; Treinen, KA | 1 |
| Moudry, R; Porzig, H | 1 |
| Giles, W; Irisawa, H; Nakajima, T; Wu, S | 1 |
| Brand, JG; Kare, MR; Katz, Y; Naim, M | 1 |
| Bankhurst, AD; Whalen, MM | 1 |
| Bonvallet, R; Lemtiri-Chlieh, F; Rougier, O | 1 |
| Hall, S; Pennefather, JN | 1 |
| Kristersson, A; Mazzoni, L; Morley, J; Sanjar, S; Schaeublin, E | 1 |
| Gupta, RC; Jagadeesh, G; Sulakhe, PV | 1 |
| Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Minato, M; Soma, M | 1 |
| Aronstam, RS; Catravas, JD; Legrand, AB; Narayanan, TK; Ryan, US | 1 |
| Gutierrez, GE; Hewlett, EL; Katz, MS; Manning, DR; Mundy, GR | 1 |
| Karaki, H; Kwon, SC; Ozaki, H; Tajimi, M | 1 |
| Buckner, CK; Graziano, FM; Undem, BJ | 1 |
| Challis, JR; Mitchell, BF; Skinner, K; Warrick, C | 1 |
| Alberts, P; Ogren, VR; Sellström, AI | 1 |
| Lindemann, JP; Watanabe, AM | 1 |
| Agus, ZS; Civan, MM; Kelepouris, E; Ziyadeh, FN | 1 |
| Hata, F; Ishida, H; Ishikawa, Y; Koda, N; Kondo, E; Noguchi, Y | 1 |
| Axelrod, J; Corda, D; Guild, S; Lewis, D; Luini, A | 1 |
| Nezu, E; Yoneyama, T; Yoshimura, K | 1 |
| Jacobson, KL; Singh, JC; Watson, EL | 2 |
| Conti, M; Geremia, R; Monaco, L; Stefanini, M | 1 |
| Hess, P; Lansman, JB; Nilius, B; Tsien, RW | 1 |
| Chao, WT; Walkenbach, RJ | 1 |
| Catherwood, BD; Chenoweth, DE; Rubin, JE | 1 |
| Cline, WH; Metz, MA; Nickols, GA | 1 |
| Madison, DV; Nicoll, RA | 1 |
| Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK | 1 |
| Stinnakre, J; Van Renterghem, C | 1 |
| Hescheler, J; Kameyama, M; Trautwein, W | 1 |
| Pappano, AJ; Rardon, DP | 1 |
| Buckner, CK; Undem, BJ | 1 |
| Ausiello, DA; Axelrod, L; Kieffer, JD; Ryan, CA; Shaw, JL | 1 |
| Hoffman, BB; Lee, CH; Tsujimoto, G | 1 |
| Copelas, L; Feldman, MD; Grossman, W; Gwathmey, JK; Morgan, JP; Phillips, P; Schoen, FJ; Warren, SE | 1 |
| Gonzalez, OF; Kreisberg, JI; Troyer, DA; Venkatachalam, MA | 1 |
| Anakwe, OO; Moger, WH | 2 |
| Cline, WH; Nickols, GA | 1 |
| Kostić, MM; Krause, EG; Maretzki, D; Rapoport, SM; Zivković, R | 1 |
| Brenner, GM; Chen, WY; Hugman, LE; Robbins, RK; Wince, LC | 1 |
| Linden, J | 1 |
| Barker, S; Cassity, N; Martinez, JR | 1 |
| Dickinson, KE; Hirschowitz, BI; Komiyama, K; Matsumoto, H; Shirakawa, T | 1 |
| Ardizzone, C; Lippe, C; Margiotta, M | 1 |
| Cary, DA; Mendelsohn, FA | 1 |
| Fischmeister, R; Hartzell, HC | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Reeves, JP; Yatani, A | 1 |
| Lichtenstein, LM; MacGlashan, DW; Peachell, PT; Schleimer, RP | 1 |
| Dreux, C; Imhoff, V; Rossignol, B | 1 |
| Jimenez, J; Moreno, FJ; Page-Peñuelas, A | 1 |
| Mobley, PL; Northam, WJ | 1 |
| Cowburn, R; Cripps, HE; Iversen, LL; Poat, JA | 1 |
| Murata, K; Ogura, Y | 1 |
| Giudicelli, Y; Leneveu, MC; Pecquery, R | 2 |
| Ascoli, M; Pereira, ME; Segaloff, DL | 1 |
| Bradbury, NA; McPherson, MA | 1 |
| Giudicelli, Y; Pasquier, YN; Pecquery, R | 1 |
| Black, EW; Strada, SJ; Thompson, WJ | 1 |
| Egan, TM; Noble, D; Noble, SJ; Powell, T; Twist, VW; Yamaoka, K | 1 |
| Deeg, MA; Goldberg, ND; Graeff, RM; Walseth, TF | 1 |
| Noda, M; Rodan, GA; Yoon, K | 1 |
| Guerrero, JM; Reiter, RJ; Santana, C; Troiani, ME | 1 |
| Kilbinger, H; Racké, K; Schwörer, H | 1 |
| Anderson, FL; Bristow, MR; Hershberger, R; Kralios, AC | 2 |
| Noda, M; Rodan, GA | 1 |
| Basta, PV; Moore, TL; Ting, JP; Yokota, S | 1 |
| Soll, AH; Toomey, M | 1 |
| Cotterell, DJ; Dubocovich, ML; Vogel, SM; Watson, JM | 1 |
| Fozzard, HA; Nakayama, T; Palfrey, C | 1 |
| Callens-el Amrani, F; Chevalier, B; Mansier, P; Swynghedauw, B | 1 |
| Axel, R; Hen, R; Obici, S | 1 |
| Baughman, KL; Cates, AE; Feldman, AM; Levine, MA; Van Dop, C | 1 |
| Lugnier, C; Schoeffter, P; Stoclet, JC; Travo, C | 1 |
| Kelly, E; Koenig, SM; Leff, AR; Mitchell, RW; Popovich, KJ; White, SR | 1 |
| Grantham, JJ; Lechene, C; Mangoo-Karim, R; Uchic, M | 1 |
| Christoffersen, T; Johansen, EJ; Refsnes, M | 1 |
| Bouvier, M; Campbell, PT; Caron, MG; Collins, S; de Blasi, A; Irons, GP; Kobilka, BK; Lefkowitz, RJ; MacGregor, C; O'Dowd, BF | 1 |
| Kotecha, N; Neild, TO | 1 |
| Malik, KU; Williams, JL | 1 |
| Christoffersen, T; Gjone, IH; Gladhaug, IP; Ostby, E; Refsnes, M; Thoresen, GH | 1 |
| Henis, YI; Moscona-Amir, E; Sokolovsky, M | 1 |
| Hagiwara, N; Irisawa, H | 1 |
| Daikoku, M; Inagaki, N; Koda, A; Miura, T; Nagai, H | 1 |
| Geisler, A; Mørk, A | 1 |
| Brown, AM; Imoto, Y; Schwartz, A; Yatani, A | 1 |
| Ishikawa, S; Sperelakis, N | 1 |
| Berkenboom, G; Fontaine, J; Unger, P | 1 |
| Fukuda, N; Hatano, M; Honda, M | 1 |
| Harvey, RD; Hume, JR | 2 |
| de Mazancourt, P; Giot, J; Giudicelli, Y | 1 |
| Bonta, IL; de Jongste, JC; Kerrebijn, KF; Mons, H | 1 |
| Yuwiler, A | 1 |
| Robertson, RP; Walseth, TF; Zhang, HJ | 1 |
| Ahmad, Z; Green, FJ; Subuhi, HS; Watanabe, AM | 1 |
| Duman, RS; Enna, SJ; Strada, SJ | 1 |
| Madelian, V; Martin, DL; Shain, W | 1 |
| Steketee, JD; Swann, AC | 1 |
| Ball, SG; Balmforth, AJ; Vaughan, PF; Yasunari, K | 1 |
| Maruta, K; Osa, T | 1 |
| Furui, H; Satake, T; Suzuki, K; Takagi, K | 1 |
| Johnson, GV; Jope, RS; Li, XH | 1 |
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| Dalal, S; Das, BC; Foster, CR; Singh, K; Singh, M | 1 |
| Darios, ES; Seitz, B; Watts, SW | 1 |
| Bakke, I; Espevik, T; Gustafsson, BI; Kidd, M; Modlin, IM; Pfragner, R; Rokstad, AM; Svejda, B | 1 |
| Asteriti, S; Daniele, S; Dell'Anno, MT; Fazzini, A; Gilchrist, A; Martini, C; Mazzoni, MR; Porchia, F; Pugliesi, I; Taliani, S; Trincavelli, ML | 1 |
| Goi, Y; Hoyano, Y; Kusama, H; Maruyama, I; Maruyama, K; Tatemichi, S; Yamazaki, Y | 1 |
| Adris, P; Bogard, AS; Ostrom, RS | 1 |
| Guan, H; Li, R; Yang, K | 1 |
| Abraham, G; Bohms, B; El-Banayosy, A; Gummert, J; Hasenfuβ, G; Kassner, A; Kolkhof, P; Milting, H; Morshuis, M; Schulte Eistrup, S; Toischer, K | 1 |
| Abe, T; Dafik, L; Ishii, K; Nakahata, N; Obara, Y; Yanagihata, Y | 1 |
| Harraz, OF; Welsh, DG | 1 |
| Gauthier, C; Grabherr, A; Lauzier, B; Merlet, N; Piriou, N; Rozec, B; Trochu, JN | 1 |
| Michel, MC; Michel-Reher, MB | 1 |
| Cottingham, C; Jiao, K; Lu, R; Wang, Q | 1 |
| Aguado, C; Alvarez, AM; Bartolomé-Martín, D; Ciruela, F; Ferrero, JJ; Godino, MC; Luján, R; Ramírez-Franco, J; Sánchez-Prieto, J; Torres, M | 1 |
| Chan, SM; Chruscinski, AJ; Singh, H; Utz, PJ | 1 |
| Bougnoux, P; Chantôme, A; Chevalier, S; Clarysse, L; Guéguinou, M; Potier-Cartereau, M; Vandecasteele, G; Vandier, C | 1 |
| Aflaki, M; Luo, X; Maguy, A; Nattel, S; Ordog, B; Qi, XY; Shi, Y; Tadevosyan, A; Tardif, JC; Xiao, L | 1 |
| Hwang, PH; Jeong, JH; Joo, NS; Wine, JJ | 1 |
| Kaumann, AJ; Newe, M; Propping, S; Ravens, U; Wirth, MP | 1 |
| Freichel, M; Mathar, I; Uhl, S; Vennekens, R | 1 |
| Barr, LA; Carter, RL; Cheung, JY; Coleman, RC; Feldman, AM; Gao, E; Grisanti, LA; Houser, SR; Koch, WJ; Li, X; Makarewich, CA; Myers, VD; Song, J; Tilley, DG; Troupes, CD; Yu, D; Zhu, W | 1 |
| Anoopkumar-Dukie, S; Grant, GD; Hempenstall, A; Johnson, PJ | 1 |
| Lorenz, K; Newe, M; Propping, S; Ravens, U; Wirth, MP | 1 |
| Bouchelouche, P; Matras, C; Nordling, J; Sheykhzade, M; Svalø, J | 1 |
| Lim, KH; Loong, BJ; Mbaki, Y; Tan, JH; Ting, KN | 1 |
| Combadière, C; de Laissardière, GT; Deterre, P; Felouzis, V; Hermand, P | 1 |
| Cao, L; Cao, YX; Li, S; Mi, YN; Ping, NN | 1 |
| Akamizu, T; Ariyasu, H; Bando, M; Dote, K; Hosoda, H; Hosoda, K; Iwakura, H; Kangawa, K; Koyama, H; Kusakabe, T; Nakao, K; Son, C | 1 |
| Cheraghpour, M; Ghorbani, A; Homayounfar, R; Jeddi-Tehrani, M; Pourvali, K; Soltani, SR; Zand, H | 1 |
| Jiang, MX; Liu, YM; Teng, MZ; Wu, DZ; Xu, YY | 1 |
| Szulczyk, B | 1 |
| Abel, T; Blackwell, KT; Gervasi, N; Girault, JA; Luczak, V | 1 |
| Ando, M; Iguchi, M; Kobayashi, S; Kobayashi, T; Matsumoto, T; Nagata, M; Taguchi, K; Watanabe, S | 1 |
| Bork, NI; Fischer, TH; Herting, J; Nikolaev, VO; Sprenger, JU | 1 |
| Simo-Cheyou, ER; Srivastava, AK; Youreva, V | 1 |
| Bartels, P; Bian, JS; Foo, R; Galupo, MJ; Herzig, S; Hoppe, UC; Hu, Z; Huang, H; Jiang, F; Li, G; Liang, MC; Liao, P; Poh, KK; Ponniah, S; See, K; Soong, TW; Trasti, SL; Wang, J; Wong, YP; Yong, TF; Yu, CY; Yu, D; Zhang, G; Zhang, H | 1 |
| Bernier, M; Indig, FE; Jozwiak, K; Paul, RK; Such, J; Wainer, IW; Wersto, RP; Wnorowski, A | 1 |
| Andersen, ES; Breining, P; Hansen, JB; Isidor, MS; Markussen, LK; Pedersen, SB; Petersen, LI; Rasmussen, NE; Richelsen, B | 1 |
| Chan, CB; Du, GH; Hu, X; Jia, WH; Tse, MCL; Yang, XY | 1 |
| Bashir, S; Elegunde, B; Morgan, WA | 1 |
| Cho, HJ; Choi, JY; Engelhardt, JF; Joo, NS; Milla, CE; Shinbashi, M; Wine, JJ | 1 |
| Kleim, M; Kömhoff, M; Laghmani, K; Nasrah, S; Quell, L; Radi, A; Schermuly, RT; Seaayfan, E; Weber, S | 1 |
| An, SS; Bochkov, YA; Cao, G; Gebski, EB; Gern, J; Kim, N; Koziol-White, CJ; Kurten, R; Lam, H; Panettieri, RA; Parikh, V | 1 |
6 review(s) available for isoproterenol and colforsin
| Article | Year |
|---|---|
Pulmonary edema: ischemia reperfusion endothelial injury and its reversal by c-AMP.
Topics: Animals; Antioxidants; Capillary Resistance; Colforsin; Cyclic AMP; Dogs; Endothelium; Free Radicals; Ischemia; Isoproterenol; Lung; Oxidation-Reduction; Oxygen; Pulmonary Circulation; Pulmonary Edema; Rabbits; Rats; Reperfusion Injury | 1991 |
Enhancement of peripheral nerve regeneration by pharmacological activation of the cyclic AMP second messenger system.
Topics: Animals; Colforsin; Cricetinae; Cyclic AMP; Drug Synergism; Isoproterenol; Nerve Regeneration; Peripheral Nerves; Rats; Second Messenger Systems; Stimulation, Chemical | 1989 |
Forskolin modulates cyclic AMP generation in the rat myometrium. Interactions with isoproterenol and prostaglandins E2 and I2.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Epoprostenol; Female; In Vitro Techniques; Isoproterenol; Membranes; Myometrium; Propranolol; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Cation channels in oocytes and early states of development: a novel type of nonselective cation channel activated by adrenaline in a clonal mesoderm-like cell line (MES-1).
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Calcium Channels; Carbachol; Cations; Cell Membrane; Clone Cells; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epinephrine; Female; Ion Channels; Isoproterenol; Mesoderm; Models, Biological; Oocytes; Serotonin; Somatostatin; Teratoma; Xenopus | 1993 |
Interleukin-1 receptors in the brain-endocrine-immune axis. Modulation by stress and infection.
Topics: Animals; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Ether; Isoproterenol; Laparotomy; Mice; Pituitary Gland; Receptors, Interleukin-1; Shock, Septic; Stress, Physiological; Tumor Cells, Cultured | 1995 |
Selective enhancement of P-type calcium currents by isoproterenol in the rat amygdala.
Topics: Adrenergic beta-Agonists; Amygdala; Animals; Calcium Channels; Colforsin; Electric Conductivity; Excitatory Postsynaptic Potentials; Isoproterenol; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 1998 |
4 trial(s) available for isoproterenol and colforsin
| Article | Year |
|---|---|
Age-dependent changes in the beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in human right atrium.
Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Blotting, Western; Child; Child, Preschool; Colforsin; Female; GTP-Binding Proteins; Heart Atria; Humans; Infant; Infant, Newborn; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Receptors, Adrenergic, beta; Terbutaline | 1995 |
Topical fat reduction.
Topics: Adipose Tissue; Aminophylline; Colforsin; Female; Humans; Injections; Isoproterenol; Lipolysis; Ointments; Thigh; Weight Loss; Yohimbine | 1995 |
Antilipolytic effect of insulin and insulin receptor messenger RNA expression in adipocytes of infants, children, and adults.
Topics: Adipocytes; Adult; Cell Size; Child; Child, Preschool; Colforsin; Female; Humans; Infant; Insulin; Isoproterenol; Lipolysis; Male; Receptor, Insulin; RNA, Messenger | 1997 |
Adipose tissue metabolism in young and middle-aged men after control for total body fatness.
Topics: Adipose Tissue; Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Aging; Body Composition; Brimonidine Tartrate; Bucladesine; Cell Separation; Colforsin; Epinephrine; Glycerol; Humans; Isoproterenol; Lipolysis; Lipoprotein Lipase; Male; Middle Aged; Quinoxalines; Theophylline | 2000 |
1583 other study(ies) available for isoproterenol and colforsin
| Article | Year |
|---|---|
Relaxant response of isolated basilar arteries to calcitonin gene-related peptide in stroke-prone spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Bucladesine; Calcitonin Gene-Related Peptide; Colforsin; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1992 |
Contrasting effects of cyclic AMP increase caused by beta-adrenergic stimulation or by adenylate cyclase activation on ventricular fibrillation threshold of isolated rat heart.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Differential Threshold; Enzyme Activation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Oxygen Consumption; Rats; Ventricular Fibrillation | 1992 |
Synergistic action of cyclic GMP on catecholamine-induced chloride current in guinea-pig ventricular cells.
Topics: Animals; Catecholamines; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart Ventricles; Histamine; Ion Channels; Isoproterenol; Membrane Potentials; Milrinone; Myocardium; Pyridones | 1992 |
A possible role of decreased relaxation mediated by beta-adrenoceptors in bladder outlet obstruction by benign prostatic hyperplasia.
Topics: Adult; Aged; Aged, 80 and over; Colforsin; Dihydroalprenolol; Humans; In Vitro Techniques; Isometric Contraction; Isoproterenol; Kinetics; Male; Membranes; Middle Aged; Muscle Relaxation; Potassium Chloride; Prazosin; Propranolol; Prostatic Hyperplasia; Radioligand Assay; Receptors, Adrenergic, beta; Urinary Bladder Neck Obstruction | 1992 |
Histamine-induced depolarization and the cyclic AMP--protein kinase A system in isolated guinea pig adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alprostadil; Animals; Carbazoles; Colforsin; Cyclic AMP; Electrophysiology; Epididymis; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Insulin; Isoproterenol; Male; Membrane Potentials; Protein Kinase C; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1992 |
Intracellular pathways triggered by galanin to induce contraction of pig ileum smooth muscle cells.
Topics: Acetylcholine; Animals; Cell Communication; Colforsin; Dose-Response Relationship, Drug; Galanin; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nifedipine; Peptides; Pertussis Toxin; Sincalide; Swine; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1992 |
Developmental changes in the beta-adrenergic modulation of calcium currents in rabbit ventricular cells.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Rabbits; Ventricular Function; Virulence Factors, Bordetella | 1992 |
Enhancement of rabbit cardiac sodium channels by beta-adrenergic stimulation.
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Phosphorylation; Rabbits; Sodium Channels; Stimulation, Chemical | 1992 |
Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries.
Topics: Animals; Arteries; Atrial Natriuretic Factor; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Protein Kinases; Second Messenger Systems; Swine | 1992 |
High plasma levels of catecholamines during insulin-induced hypoglycemic stress do not cause beta-adrenergic receptor sequestration.
Topics: Adrenal Medulla; Adult; Catecholamines; Colforsin; Cyclic AMP; Epinephrine; Female; Humans; Hypoglycemia; Insulin; Isoproterenol; Leukocytes; Male; Middle Aged; Receptors, Adrenergic, beta; Stress, Physiological | 1992 |
Long-term increases in excitability in the CA1 region of rat hippocampus induced by beta-adrenergic stimulation: possible mediation by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Colforsin; Cyclic AMP; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Neurons; Pyramidal Tracts; Rats; Receptors, Adrenergic, beta; Thionucleotides; Time Factors | 1992 |
Reversal of increased microvascular permeability associated with ischemia-reperfusion: role of cAMP.
Topics: Animals; Bucladesine; Capillary Permeability; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Lung; Lung Injury; Male; Perfusion; Pulmonary Circulation; Rats; Reperfusion Injury | 1992 |
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Iodocyanopindolol; Isoproterenol; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Pindolol; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1992 |
The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes.
Topics: Acetates; Amyloid; Animals; Arginine; Blood Glucose; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Islet Amyloid Polypeptide; Isoproterenol; Kinetics; Lipid Metabolism; Liver; Liver Glycogen; Male; Mice; Mice, Inbred Strains; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Thymidine | 1992 |
Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon.
Topics: Adenylate Cyclase Toxin; Animals; Binding, Competitive; Cell Membrane; Clonidine; Colforsin; Colon; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 1992 |
Ion transport by primary cultures of Mongolian gerbil middle ear epithelium.
Topics: Amiloride; Animals; Arginine Vasopressin; Biological Transport; Bradykinin; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Ear, Middle; Epithelium; Gerbillinae; Glucagon; Histamine; Indomethacin; Isoproterenol; Male; Mannitol; Microscopy, Electron; Parathyroid Hormone; Sodium | 1992 |
Compounds that increase cAMP prevent ischemia-reperfusion pulmonary capillary injury.
Topics: Animals; Bucladesine; Capillaries; Capillary Permeability; Colforsin; Cyclic AMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Lung; Lung Injury; Rabbits; Reperfusion Injury; Vascular Resistance | 1992 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
NPY-stimulated Ca2+ mobilization in SK-N-MC cells is enhanced after isoproterenol treatment.
Topics: Adenylyl Cyclases; Calcium; Cell Line; Colforsin; Cyclic AMP; Cycloheximide; Enzyme Activation; Homeostasis; Humans; Intracellular Membranes; Isoproterenol; Neuropeptide Y; Time Factors | 1992 |
A2-adenosine receptor stimulation increases macromolecule permeability of coronary endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Capillary Permeability; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Energy Metabolism; Isoproterenol; Macromolecular Substances; Microscopy, Electron, Scanning; Receptors, Purinergic | 1992 |
Ca2+ mobilization by the LH receptor expressed in Xenopus oocytes independent of 3',5'-cyclic adenosine monophosphate formation: evidence for parallel activation of two signaling pathways.
Topics: Adenylyl Cyclases; Animals; Calcium; Chlorides; Cloning, Molecular; Colforsin; Cyclic AMP; Egtazic Acid; Humans; Isoproterenol; Mice; Oocytes; Receptors, Adrenergic, beta; Receptors, LH; Signal Transduction; Transcription, Genetic; Xenopus | 1992 |
Effects of isoproterenol and forskolin on carbachol- and fluoroaluminate-induced polyphosphoinositide hydrolysis, inositol trisphosphate production, and contraction in bovine iris sphincter smooth muscle: interaction between cAMP and IP3 second messenger
Topics: Aluminum; Animals; Carbachol; Cattle; Colforsin; Cyclic AMP; Deferoxamine; Fluorine; Hydrolysis; Inositol 1,4,5-Trisphosphate; Iris; Isoproterenol; Kinetics; Muscle Contraction; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Second Messenger Systems; Sodium Fluoride | 1992 |
Beta-adrenergic responsiveness in cultured aorta smooth muscle cells. Effects of subculture and aging.
Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Isoproterenol; Microscopy, Phase-Contrast; Muscle, Smooth, Vascular; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1992 |
Evidence that MEHP inhibits rat granulosa cell function by a protein kinase C-independent mechanism.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diethylhexyl Phthalate; Female; Follicle Stimulating Hormone; Granulosa Cells; Isoproterenol; Progesterone; Protein Kinase C; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate | 1992 |
Prostacyclin is a specific effector of adipose cell differentiation. Its dual role as a cAMP- and Ca(2+)-elevating agent.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Calcium; Cations, Divalent; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Epoprostenol; Glycerolphosphate Dehydrogenase; Ionomycin; Isoproterenol; Mice; Mitogens; Protein Kinases | 1992 |
Atrial natriuretic peptide suppresses isoprenaline and dibutyryl cyclic adenosine monophosphate-induced cell growth in cultured renin-secreting human nephroblastoma cells. Comparison with forskolin-induced renin secretion.
Topics: Atrial Natriuretic Factor; Bucladesine; Colforsin; Humans; In Vitro Techniques; Isoproterenol; Kidney Neoplasms; Propranolol; Renin; Time Factors; Tumor Cells, Cultured; Wilms Tumor | 1992 |
Intracellular cyclic AMP concentration modulates gap junction permeability in parturient rat myometrium.
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Electrophysiology; Female; Histocytochemistry; In Vitro Techniques; Isoproterenol; Isoquinolines; Labor, Obstetric; Microelectrodes; Myometrium; Neuromuscular Junction; Permeability; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
Agonist-related differences in the relationship between cAMP content and protein kinase activity in canine trachealis.
Topics: Animals; Colforsin; Cyclic AMP; Dogs; Drug Interactions; Female; Isoproterenol; Male; Muscle Relaxation; Protein Kinases; Trachea | 1992 |
Delta and kappa opiate receptors in primary astroglial cultures. Part II: Receptor sets in cultures from various brain regions and interactions with beta-receptor activated cyclic AMP.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Animals; Astrocytes; Brain Stem; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Isoproterenol; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1992 |
Mechanisms of vasodilation induced by NKH477, a water-soluble forskolin derivative, in smooth muscle of the porcine coronary artery.
Topics: Acetylcholine; Animals; Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoproterenol; Muscle, Smooth, Vascular; Potassium; Solubility; Swine; Vasoconstriction; Vasodilation; Water | 1992 |
Sodium-pump injury and arrhythmogenic transient depolarizations in catecholamine-induced cardiac hypertrophy.
Topics: Action Potentials; Animals; Body Weight; Cardiomegaly; Colforsin; Electric Stimulation; Heart; Isoproterenol; Male; Organ Size; Rats; Rats, Inbred Strains; Ryanodine; Sodium-Potassium-Exchanging ATPase | 1992 |
Catecholamine-induced cardiac hypertrophy uncouples beta-adrenoceptors from slow calcium channels.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium Channels; Cardiomegaly; Colforsin; Electric Stimulation; Heart; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1992 |
Rapid inverse changes in alpha 1B- and beta 2-adrenergic receptors and gene transcripts in acutely isolated rat liver cells.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Glucagon; Inositol 1,4,5-Trisphosphate; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger; Time Factors; Transcription, Genetic | 1992 |
Alteration of beta-adrenoceptor function in hypertensive patients with different degrees of left ventricular hypertrophy.
Topics: Adult; Blood Pressure; Cardiomegaly; Colforsin; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Receptors, Adrenergic, beta | 1992 |
Down-regulation of CGRP-mediated cAMP accumulation in ras-transformed 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Calcitonin Gene-Related Peptide; Cell Line, Transformed; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Genes, ras; Isoproterenol; Kinetics; Mice | 1992 |
Hormonal activation of the cGMP-inhibited low-Km cyclic AMP phosphodiesterase of rat adipocytes from different sites: influence of ovariectomy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Insulin; Isoproterenol; Ovariectomy; Ovary; Protein Kinases; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
Melanocortins stimulate proliferation and induce morphological changes in cultured rat astrocytes by distinct transducing mechanisms.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Culture Techniques; Cyclic AMP; DNA Replication; Isoproterenol; Kinetics; Melanocyte-Stimulating Hormones; Rats; Thymidine | 1992 |
Overexpression of alpha 2-adrenergic receptors in fetal rat heart: receptors in search of a function.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Clonidine; Colforsin; Fetal Heart; Gestational Age; In Vitro Techniques; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Specific inhibition of isoproterenol-stimulated cyclic AMP accumulation by M2 muscarinic receptors in rat intestinal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Enzyme Activation; Ileum; Isoproterenol; Male; Muscle, Smooth; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1992 |
[Membrane mechanisms of the relaxing effect of cyclic adenosine monophosphate in myometrial smooth muscle fibers].
Topics: Animals; Biological Transport; Calcium; Cations, Divalent; Cell Membrane; Colforsin; Cyclic AMP; Female; Isoproterenol; Kinetics; Membrane Potentials; Muscle Relaxation; Myometrium; Protein Kinases; Swine | 1992 |
Adenylyl cyclase and guanine nucleotide-binding proteins in supersensitive guinea pig ventricles.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guinea Pigs; Heart Ventricles; Impromidine; Isoproterenol; Male; Myocardium; Reserpine | 1992 |
Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).
Topics: Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Ethers, Cyclic; In Vitro Techniques; Isoproterenol; Isoquinolines; Nitric Oxide; Nitroprusside; Okadaic Acid; Protein Kinases; Swine | 1992 |
Oxygen modulates prostacyclin synthesis in ovine fetal pulmonary arteries by an effect on cyclooxygenase.
Topics: Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Isoproterenol; Muscle, Smooth, Vascular; Oxygen; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Pulmonary Artery; Signal Transduction; Swine | 1992 |
Prostaglandin E2 synthesis elicited by adrenergic stimuli in guinea pig trachea is mediated primarily via activation of beta 2 adrenergic receptors.
Topics: Albuterol; Animals; Arachidonic Acid; Butoxamine; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Dobutamine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Practolol; Receptors, Adrenergic, beta; Time Factors; Trachea | 1992 |
Identification of cis- and trans-acting factors regulating the expression of rat salivary-specific RP4 gene.
Topics: Animals; Base Sequence; Cell Line; Colforsin; Consensus Sequence; Cyclic AMP; Enzyme Induction; Gene Expression Regulation; HeLa Cells; Humans; Isoproterenol; Molecular Sequence Data; Organ Specificity; Peptide Biosynthesis; Peptides; Proline-Rich Protein Domains; Propranolol; Protein Kinases; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Salivary Glands; Salivary Proteins and Peptides; Sequence Homology, Nucleic Acid; Theophylline; Transcription Factors | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Nitroprusside; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1992 |
[Modulation of the adenylate cyclase-cAMP pathway by protein kinase C in chick retinal pigment epithelium].
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Isoproterenol; Pigment Epithelium of Eye; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Muscarinic receptors in MDCK cells are coupled to multiple messenger systems.
Topics: Adenylate Cyclase Toxin; Animals; Arginine Vasopressin; Cell Line; Colforsin; Cyclic AMP; Dogs; Hydrolysis; Isoproterenol; Kidney; Muscarine; Parasympathomimetics; Pertussis Toxin; Phosphatidylinositols; Receptors, Muscarinic; Second Messenger Systems; Virulence Factors, Bordetella | 1992 |
Reduced contractile responses to forskolin and a cyclic AMP analogue in myocytes from failing human ventricle.
Topics: Adult; Aging; Bucladesine; Calcium; Colforsin; Diuretics; Female; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction | 1992 |
Differential responsiveness to agents which stimulate cAMP production in normal versus neoplastic mouse lung epithelial cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Isoproterenol; Lung; Lung Neoplasms; Mice; Receptors, Adrenergic, beta; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured | 1992 |
Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Body Weight; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Heart; Isoproterenol; Kidney; Maternal-Fetal Exchange; Myocardium; Organ Size; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1992 |
Dissociation of magnitude of relaxation from cyclic AMP levels in rabbit urinary bladder smooth muscles.
Topics: Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Rabbits; Urinary Bladder | 1992 |
Effect of catecholamines on intracellular pH in sheep cardiac Purkinje fibres.
Topics: Animals; Colforsin; Cyclic AMP; Epinephrine; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Membrane Potentials; Phenylephrine; Proton Pumps; Purkinje Fibers; Sheep; Sodium-Potassium-Exchanging ATPase | 1992 |
Regional difference in the response mediated by beta 1-adrenoceptor subtype in bovine cerebral arteries.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Cerebral Arteries; Colforsin; Dose-Response Relationship, Drug; Homeostasis; Isoproterenol; Metoprolol; Norepinephrine; Receptors, Adrenergic, beta; Terbutaline | 1992 |
Preferential desensitization of beta- versus alpha 2-adrenergic receptors accelerates loss of response to norepinephrine in primary glial cultures.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Female; Isoproterenol; Neuroglia; Norepinephrine; Pregnancy; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Characteristics of the alpha 2/beta-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cricetinae; Dioxanes; Epididymis; Epinephrine; GTP-Binding Proteins; Idazoxan; Isoproterenol; Kinetics; Lipolysis; Macromolecular Substances; Male; Mesocricetus; Organ Specificity; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Theophylline | 1992 |
Adrenergic receptor-mediated increase of intracellular Ca2+ concentration in isolated bovine corneal epithelial cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cattle; Colforsin; Cornea; Epithelial Cells; Epithelium; Isoproterenol; Methoxamine; Receptors, Adrenergic; Second Messenger Systems; Verapamil | 1992 |
Somatostatin binding to a fresh rat astrocyte-enriched suspension.
Topics: Animals; Astrocytes; Cerebral Cortex; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Rats; Somatostatin; Vasoactive Intestinal Peptide | 1992 |
Adrenergic mechanisms associated with the movement of platelets in iridophores from the freshwater goby, Odontobutis obscura.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Platelets; Cell Movement; Cells, Cultured; Chromatophores; Colforsin; Cyclic GMP; Fishes; Isoproterenol; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Relaxation of soman-induced contracture of airway smooth muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Colforsin; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Soman; Theophylline; Trachea | 1992 |
The immune response evokes up- and down-modulation of beta 2-adrenergic receptor messenger RNA concentration in the male rat thymus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Down-Regulation; Gene Expression Regulation; Immunization; Isoproterenol; Male; Neuroimmunomodulation; Norepinephrine; Poly A; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Serum Albumin, Bovine; Thymus Gland; Up-Regulation | 1992 |
Differential sensitivities of the prostacyclin and nitric oxide biosynthetic pathways to cytosolic calcium in bovine aortic endothelial cells.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Bradykinin; Calcium; Cattle; Cells, Cultured; Colforsin; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Ionomycin; Isoproterenol; Nitric Oxide; Propanolamines | 1992 |
Occupancy-response relationships for beta- and alpha 2-adrenergic receptors exerting opposing effects on cAMP production.
Topics: Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Neuroglia; Norepinephrine; Pindolol; Quinolines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1992 |
Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Cholera Toxin; Colforsin; Cyclic AMP; Dioxanes; Down-Regulation; Glioma; Idazoxan; Isoproterenol; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1992 |
2-Aminopurine inhibits RNA and protein synthesis and reduces catecholamine desensitization in C6-2B rat glioma cells.
Topics: 2-Aminopurine; 3T3 Cells; Animals; Bucladesine; Catecholamines; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression; Glioma; HeLa Cells; Humans; Isoproterenol; Methionine; Mice; Mice, Inbred BALB C; Protein Biosynthesis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Rats; RNA; RNA, Messenger; Tumor Cells, Cultured; Uridine | 1992 |
cAMP and Ca(2+)-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton.
Topics: 1-Methyl-3-isobutylxanthine; Actins; alpha-Amylases; Animals; Biomarkers; Bucladesine; Calcium; Calcium Chloride; Carbachol; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cytoskeleton; Egtazic Acid; Guinea Pigs; Isoproterenol; Male; Microfilament Proteins; Parotid Gland | 1992 |
Activation of beta-adrenergic receptors inhibits Ca2+ entry-mediated generation of inositol phosphates in the guinea pig myometrium, a cyclic AMP-independent event.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aluminum; Animals; Calcium; Calcium Channels; Carbachol; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Drug Antagonism; Female; Fluorine; Guinea Pigs; Inositol Phosphates; Ionomycin; Isoproterenol; Myometrium; Nifedipine; Oxytocin; Pertussis Toxin; Receptors, Adrenergic, beta; Type C Phospholipases; Verapamil; Virulence Factors, Bordetella | 1992 |
Isoproterenol-stimulated labelling of particulate proteins by using [adenylate-32P]NAD+ independent on a cAMP-dependent protein kinase in parotid acinar cells.
Topics: Amylases; Cell Membrane Permeability; Colforsin; Cyclic AMP; Isoproterenol; NAD; Parotid Gland; Phosphodiesterase I; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Propranolol; Saponins | 1992 |
Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Animals; Carbachol; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Histamine; Ion Channels; Isoproterenol; Membrane Proteins; Myocardium; Pertussis Toxin; Phosphorylation; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors; Virulence Factors, Bordetella | 1992 |
Cyclic AMP-induced upregulation of proteolipid protein and myelin associated glycoprotein gene expression in C6 cells.
Topics: Animals; Blotting, Northern; Cell Nucleus; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Myelin Proteins; Myelin-Associated Glycoprotein; Nucleic Acid Hybridization; Proteolipids; Rats; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 1992 |
Effect of albumin on adenylate cyclase receptor-related signal transduction of human peripheral blood mononuclear cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Histamine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Monocytes; Serum Albumin; Signal Transduction | 1992 |
Modulation of potassium channels in intact human T lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Dinoprostone; Electric Stimulation; Histamine; Humans; Isoproterenol; Potassium Channels; T-Lymphocytes; Temperature | 1992 |
Profile of cardiovascular effects of NKH477, a novel forskolin derivative, assessed in isolated, blood-perfused dog heart preparations: comparison with isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Atrioventricular Node; Colforsin; Dogs; Dose-Response Relationship, Drug; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Papillary Muscles; Sinoatrial Node; Vasodilator Agents | 1992 |
Regulation of secretion by vasoactive intestinal peptide in isolated perfused rat submandibular glands.
Topics: Acetylcholine; Alprostadil; Animals; Chemotherapy, Cancer, Regional Perfusion; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Saliva; Salivary Proteins and Peptides; Secretory Rate; Submandibular Gland; Substance P; Vasoactive Intestinal Peptide | 1992 |
The effects of P1- and muscarinic-receptor agonists upon cAMP-dependent and independent inotropic responses of guinea-pig cardiac preparations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Receptors, Muscarinic; Receptors, Purinergic | 1992 |
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Freeze Fracturing; Glioma; Guinea Pigs; Immunohistochemistry; Isoproterenol; Lectins; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinases; Rats; Retina; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Role of cAMP in the functional interaction of carbachol with different cAMP elevating agents in rabbit atrium.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Analysis of Variance; Animals; Carbachol; Colforsin; Cyclic AMP; Depression, Chemical; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1992 |
Control of cyclic AMP levels in primary cultures of human tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Carbachol; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Muscle, Smooth; Phosphodiesterase Inhibitors; Propanolamines; Trachea | 1992 |
The indirect negative inotropic effects of the P1-receptor agonist, L-phenylisopropyladenosine, in guinea-pig isolated cardiac preparations: comparison with cromakalim.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Atrial Function, Left; Benzopyrans; Cardiotonic Agents; Colforsin; Cromakalim; Depression, Chemical; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Pyrroles; Stimulation, Chemical; Time Factors | 1992 |
The ANF-C receptor is not linked to adenylyl cyclase inhibition in bovine pulmonary artery endothelial cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cattle; Cell Line; Colforsin; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanylyl Imidodiphosphate; Isoproterenol; Pulmonary Artery; Receptors, Atrial Natriuretic Factor | 1992 |
Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Cloning, Molecular; Colforsin; DNA; Gene Expression; Isoproterenol; Kidney; Liver; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Tissue Distribution | 1992 |
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; GTP-Binding Proteins; Isoproterenol; Magnesium; Mice; Mice, Inbred CBA; Obesity; Secretin | 1992 |
Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Colforsin; Hydrogen; Hypercapnia; Indomethacin; Isoproterenol; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Pia Mater; Potassium; Swine; Vasoconstriction; Vasodilation | 1992 |
Positive inotropic effects of CGRP and isoprenaline: analogies and differences.
Topics: Animals; Calcitonin Gene-Related Peptide; Cardiotonic Agents; Cholera Toxin; Colforsin; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male | 1992 |
Adenosine-sensitive afterdepolarizations and triggered activity in guinea pig ventricular myocytes.
Topics: Action Potentials; Adenosine; Animals; Arrhythmias, Cardiac; Colforsin; Dideoxyadenosine; Female; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Quinidine; Receptors, Purinergic; Ventricular Function | 1992 |
Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cells, a neuroendocrine cell line: implications for neuropeptide biosynthesis.
Topics: Animals; Astrocytes; Calcimycin; Carboxypeptidase H; Carboxypeptidases; Cells, Cultured; Colforsin; Isoproterenol; Methionine; Mice; Neuropeptides; Neurosecretory Systems; Pituitary Gland; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1992 |
Reduced adenylyl cyclase inhibition by carbachol and GTP during acute myocardial ischaemia.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Colforsin; Coronary Disease; Dogs; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Receptors, Muscarinic | 1992 |
Cyclic AMP-dependent regulation of the number of [3H]batrachotoxinin benzoate binding sites on rat cardiac myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Batrachotoxins; Binding Sites; Cholera Toxin; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Neurotoxins; Pertussis Toxin; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Sodium Channels; Virulence Factors, Bordetella | 1991 |
Diabetes alters the responses of glucagon secreting cells and vascular bed to isoprenaline and forskolin in vitro in rat pancreas.
Topics: Adenylyl Cyclases; Animals; Blood Flow Velocity; Colforsin; Diabetes Mellitus, Experimental; Glucagon; Insulin; Isoproterenol; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasodilation | 1991 |
Biochemical and electrical aspects of the tracheal relaxant action of AH 21-132.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Action Potentials; Airway Resistance; Animals; Benzopyrans; Biomechanical Phenomena; Cell Membrane; Colforsin; Cromakalim; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Naphthyridines; Nucleotides, Cyclic; Papaverine; Pyrroles; Sodium Nitrite; Stereoisomerism; Trachea | 1991 |
Beta-adrenergic responsiveness in cultured vascular smooth muscle cells and fibroblasts: effect of age.
Topics: Aging; Analysis of Variance; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Regression Analysis | 1991 |
Chronic exposure of C6 glioma cells to desipramine desensitizes beta-adrenoceptors, but increases KL/KH ratio.
Topics: Animals; Cholera Toxin; Colforsin; Cyclic AMP; Desipramine; GTP-Binding Proteins; Isoproterenol; Kinetics; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1991 |
Functional endothelin-1 receptors in rat astrocytoma C6.
Topics: Animals; Aorta; Astrocytoma; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Endothelins; Inositol Phosphates; Isoproterenol; Kinetics; Rats; Receptors, Cell Surface; Receptors, Endothelin; Thymidine; Tumor Cells, Cultured; Viper Venoms | 1991 |
Dysfunction of the beta- and alpha-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog.
Topics: Adenylyl Cyclases; Animals; Cardiac Pacing, Artificial; Colforsin; Dogs; Guanylyl Imidodiphosphate; Heart Failure; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Norepinephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase | 1991 |
Stoichiometry of receptor-Gs-adenylate cyclase interactions.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Colforsin; GTP-Binding Proteins; Isoproterenol; Lymphoma; Mice; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1991 |
Different mechanisms of beta-adrenoceptor down-regulation by chronic imipramine and electroconvulsive treatment: possible role for protein kinase C.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Down-Regulation; Electroconvulsive Therapy; Imipramine; Isoproterenol; Male; Norepinephrine; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1991 |
Effects of bradykinin on intracellular calcium regulation in human ciliated airway epithelium.
Topics: Adult; Bradykinin; Bucladesine; Calcium; Cilia; Colforsin; Cyclic AMP; Female; Humans; Indomethacin; Intracellular Membranes; Isoproterenol; Male; Middle Aged; Nasal Mucosa; Osmolar Concentration | 1991 |
Neutrophil beta-adrenergic receptor responses are potentiated by acute exposure to phorbol ester without changes in receptor distribution or coupling.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Humans; Isoproterenol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1991 |
Adriamycin-induced changes to the myocardial beta-adrenergic system in the rabbit.
Topics: Adenylyl Cyclases; Animals; Colforsin; Doxorubicin; Female; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Rabbits; Receptors, Adrenergic, beta | 1991 |
Cyclic AMP counteracts mitogen-induced inositol phosphate generation and increases in intracellular Ca2+ concentrations in human lymphocytes.
Topics: Adult; Alprostadil; Calcium; Catecholamines; Colforsin; Concanavalin A; Cyclic AMP; Humans; In Vitro Techniques; Inositol Phosphates; Isoproterenol; Lymphocytes; Mitogens; Phytohemagglutinins; Pokeweed Mitogens | 1991 |
Regulation of Ca2+ current in frog ventricular cardiomyocytes by 5'-guanylylimidodiphosphate and acetylcholine.
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Colforsin; Drug Synergism; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardium; Rana catesbeiana | 1991 |
Evidence for presence of functional beta-adrenoceptor in rabbit S2 proximal straight tubules.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Bucladesine; Calcium; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP; Electrophysiology; Epithelium; Female; In Vitro Techniques; Isoproterenol; Kidney Tubules, Proximal; Kinetics; Membrane Potentials; Perfusion; Potassium; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sodium; Sodium-Bicarbonate Symporters; Sodium-Potassium-Exchanging ATPase | 1991 |
Cyclic adenosine monophosphate-stimulating agents induce ecto-5'-nucleotidase activity and inhibit DNA synthesis in rat cultured mesangial cells.
Topics: 5'-Nucleotidase; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; DNA; Enzyme Induction; Glomerular Mesangium; Isoproterenol; Rats; Thymidine | 1991 |
Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Body Weight; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Glucose; Humans; Isoproterenol; Obesity; Phenylisopropyladenosine; Receptors, Purinergic; Xanthines | 1991 |
Reduced responsiveness of adenylate cyclase to forskolin in human lymphoma cells.
Topics: Adenylyl Cyclase Inhibitors; Aged; B-Lymphocytes; Binding Sites; Cholera Toxin; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphoma, Non-Hodgkin; Male; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Signal Transduction; Tumor Cells, Cultured | 1991 |
Control of adenylate cyclase activity in developing rat heart and liver: effects of prenatal exposure to terbutaline or dexamethasone.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Cell Membrane; Colforsin; Dexamethasone; Female; Heart; Isoproterenol; Liver; Myocardium; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Terbutaline | 1991 |
Beta-adrenergic signal transduction in aging parotid and submandibular salivary glands.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Female; Isoproterenol; Parotid Gland; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Regression Analysis; Signal Transduction; Submandibular Gland | 1991 |
Ontogeny of beta-adrenergic receptor-mediated cyclic AMP generating system in primary cultured neurons.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Animals; Brain; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dihydroalprenolol; Fetus; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Mice; Mice, Inbred Strains; Neurons; Pertussis Toxin; Receptors, Adrenergic, beta; Sodium Fluoride; Virulence Factors, Bordetella | 1991 |
Hydrogen peroxide reduces beta-adrenoceptor function in the rat small intestine.
Topics: Animals; Bucladesine; Colforsin; Duodenum; Hydrogen Peroxide; Ileum; Intestine, Small; Isoproterenol; Jejunum; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxidation-Reduction; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Phorbol esters do not influence the maturation and the beta-adrenergic responsiveness of differentiated adipose precursor cells, cultured in a charcoal-treated serum medium.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blood; Cell Differentiation; Cells, Cultured; Charcoal; Colforsin; Culture Media; Isoproterenol; Lipolysis; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stem Cells; Tetradecanoylphorbol Acetate | 1991 |
cAMP-dependent down-regulation of endothelin-1 receptors on rat astrocytoma C6 cells.
Topics: Animals; Astrocytoma; Bucladesine; Colforsin; Cyclic AMP; Down-Regulation; Endothelins; Iodine Radioisotopes; Isoproterenol; Norepinephrine; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Endothelin | 1991 |
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitroarginine; Nitroprusside; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Inefficient muscarinic transduction in cardiomyopathic Syrian hamsters.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cardiomyopathies; Colforsin; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Isoproterenol; Mesocricetus; N-Methylscopolamine; Parasympatholytics; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction | 1991 |
Functional antagonism in rabbit pulmonary veins contracted by endothelin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Rabbits; Receptors, Cell Surface | 1991 |
Ontogeny of beta-adrenergic regulation of adenylate cyclase in intrapulmonary arteries from fetal and postnatal lambs.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Female; Fetus; Isoproterenol; Muscle, Smooth, Vascular; Pregnancy; Pulmonary Artery; Receptors, Adrenergic, beta; Sheep; Vasodilation | 1991 |
Thyroid hormone differentially regulates development of beta-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Body Weight; Bucladesine; Colforsin; Heart; Isoproterenol; Kidney; Myocardium; Organ Size; Ornithine Decarboxylase; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Triiodothyronine | 1991 |
Cyclic AMP and adaptive supersensitivity in guinea pig atria.
Topics: Animals; Atrial Function; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Reference Values; Reserpine | 1991 |
Potentiation by cyclic GMP of beta-adrenergic effect on Ca2+ current in guinea-pig ventricular cells.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dialysis; Drug Synergism; Guinea Pigs; Heart; Isoproterenol; Myocardium; Protein Kinases | 1991 |
Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure.
Topics: Adenylyl Cyclases; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Heart; Isoproterenol; Kidney; Male; Maternal-Fetal Exchange; Myocardium; Organ Size; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1991 |
Dose-dependent stimulation of adenylate cyclase in rat hippocampal tissue by isoprenaline, Gpp(NH)p and forskolin: lack of circadian phase-dependency.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Circadian Rhythm; Colforsin; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hippocampus; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction | 1991 |
Multiple adrenergic receptor subtypes controlling cyclic AMP formation: comparison of brain slices and primary neuronal and glial cultures.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Synergism; Isoproterenol; Kinetics; Neuroglia; Neurons; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1991 |
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine | 1991 |
Altered responsiveness of hypertrophied rat hearts to alpha- and beta-adrenergic stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium; Cardiomegaly; Colforsin; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1991 |
In vivo adaptive control of beta-receptors and adenylate cyclase during short-term heat exposure in rat parotid glands.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chlorides; Colforsin; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Isoproterenol; Male; Manganese; Manganese Compounds; Membranes; Norepinephrine; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptic Transmission; Time Factors | 1991 |
Receptor regulation of the glutamate, GABA and taurine high-affinity uptake into astrocytes in primary culture.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Colforsin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoproterenol; Kinetics; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Taurine; Virulence Factors, Bordetella | 1991 |
Beta-adrenoceptors and adenylate cyclase activity in hypertrophied and failing rabbit left ventricle.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cardiomegaly; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Heart Arrest; Isoproterenol; Male; Nucleotidases; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Sodium Fluoride | 1991 |
Antidiuretic hormone stimulation of adenylate cyclase in semicircular canal epithelium.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Calcitonin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Endolymph; Epithelium; Glucagon; Isoproterenol; Norepinephrine; Organ Culture Techniques; Parathyroid Hormone; Rana esculenta; Semicircular Canals; Vasopressins; Vasotocin | 1991 |
Effects of porcine relaxin on contraction, membrane response and cyclic AMP content in rat myometrium in comparison with the effects of isoprenaline and forskolin.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cold Temperature; Colforsin; Cyclic AMP; Electrophysiology; Estrogens; Female; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Membranes; Myometrium; Ovariectomy; Pregnancy; Rats; Relaxin; Swine; Uterine Contraction | 1991 |
Expression of functional pituitary somatostatin receptors in Xenopus oocytes.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Female; Isoproterenol; Oocytes; Pituitary Gland; Pituitary Neoplasms; Protein Biosynthesis; Receptors, Neurotransmitter; Receptors, Somatostatin; RNA; Somatostatin; Xenopus laevis | 1990 |
Roles of the AMP-activated and cyclic-AMP-dependent protein kinases in the adrenaline-induced inactivation of acetyl-CoA carboxylase in rat adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetyl-CoA Carboxylase; Adipose Tissue; Amino Acid Sequence; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Isoproterenol; Kinetics; Ligases; Molecular Sequence Data; Phosphorylation; Protein Kinases; Rats; Serine | 1990 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Isoproterenol; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats.
Topics: 1-Methyl-3-isobutylxanthine; Aminophylline; Animals; Arteries; Cardiotonic Agents; Colforsin; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyridazines; Rats; Rats, Inbred Strains; Vasodilator Agents; Veins | 1990 |
Multiple hormone actions: the rises in cAMP and Ca++ in MDCK-cells treated with glucagon and prostaglandin E1 are independent processes.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Dogs; Fluorescent Dyes; Glucagon; Indoles; Isoproterenol; Kidney; Kinetics; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1990 |
Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Chloride; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Myocardium; Protoveratrines; Pyrazines; Pyridones; Sodium | 1990 |
Epidermal growth factor potentiates cyclic AMP accumulation in A-431 cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Squamous Cell; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Epidermal Growth Factor; Humans; Isoproterenol; Kinetics; Tumor Cells, Cultured | 1990 |
Testosterone treatment of ovariectomized rats: effects on lipolysis regulation in adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Bucladesine; Colforsin; Cyclic AMP; Epinephrine; Female; Isoproterenol; Lipolysis; Norepinephrine; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Testosterone | 1990 |
Increase in calcium channel current by beta-adrenoceptor agonists in single smooth muscle cells isolated from porcine coronary artery.
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Animals; Cadmium; Calcium Channels; Colforsin; Coronary Vessels; In Vitro Techniques; Ion Channels; Isoproterenol; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Phentolamine; Swine; Tetraethylammonium Compounds | 1990 |
Cyclic AMP induces insulin-like growth factor I synthesis in osteoblast-enriched cultures.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Fetus; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Isoproterenol; Kinetics; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Rats, Inbred Strains; Somatomedins; Teriparatide; Theophylline; Transcription, Genetic | 1990 |
Vasoactive intestinal peptide stimulates chick pineal melatonin production and interacts with other stimulatory and inhibitory agents but does not show alpha 1-adrenergic potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Drug Interactions; Isoproterenol; Kinetics; Light; Melatonin; Nitrendipine; Norepinephrine; Phenylephrine; Pineal Gland; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Hydrogen-Ion Concentration; Intercellular Junctions; Isoproterenol; Kinetics; Mathematics; Models, Biological; Oocytes; Phorbol 12,13-Dibutyrate; Potassium Channels; Xenopus laevis | 1990 |
cAMP and human neutrophil chemotaxis. Elevation of cAMP differentially affects chemotactic responsiveness.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Biological Transport; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Time Factors | 1991 |
Two mechanisms of inhibition by prostaglandin E2 of hormone-dependent cell cAMP in the rat collecting tubule.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Isoproterenol; Kidney Tubules, Collecting; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Signal Transduction; Xanthines | 1990 |
Cardiac inotropic responses to calcium and forskolin are not altered by prolonged isoproterenol infusion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Drug Interactions; Heart; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Radioligand Assay; Rats; Receptors, Adrenergic, beta | 1990 |
Cyclic AMP does not inhibit A23187-induced prostaglandin biosynthesis in cultured rabbit renal microvascular endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Endothelium, Vascular; Epoprostenol; Isoproterenol; Kidney Glomerulus; Microcirculation; Rabbits | 1990 |
Possible involvement of pertussis toxin-sensitive GTP-binding protein(s) in c-fos expression during differentiation of 3T3-L1 fibroblasts to adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Blotting, Northern; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Dexamethasone; DNA-Binding Proteins; Fibroblasts; Glycerolphosphate Dehydrogenase; GTP-Binding Proteins; Insulin; Isoproterenol; Mice; Pertussis Toxin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; RNA; Virulence Factors, Bordetella | 1991 |
Cyclic-AMP-dependent phosphorylation modulates the stereospecific activation of cardiac Ca channels by Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Drug Combinations; Electric Conductivity; Heart; Isoproterenol; Membrane Potentials; Myocardium; Phosphorylation; Rats | 1990 |
Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Antisense Elements (Genetics); Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Deoxyglucose; Glucagon; Isoproterenol; Kinetics; Mice; Monosaccharide Transport Proteins; RNA; Transcription, Genetic | 1991 |
Pharmacological evidence for two types of myocardial sarcoplasmic reticulum Ca2+ release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Anesthetics, Local; Animals; Caffeine; Calcium; Colforsin; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Ryanodine; Sarcolemma; Sodium | 1991 |
Regulation of endothelin-mediated calcium mobilization in vascular smooth muscle cells by isoproterenol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelins; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Potassium; Propranolol | 1991 |
Serum-induced sensitization of cyclic AMP accumulation in 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Astrocytoma; Blood; Cholera Toxin; Colforsin; Culture Media; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Pertussis Toxin; Protein Kinase C; Receptors, Cell Surface; Staurosporine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Calcium currents in the A7r5 smooth muscle-derived cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Cell Line; Colforsin; Cytosol; Dihydropyridines; Electric Conductivity; Fluorescence; Isoproterenol; Ligands; Muscle, Smooth, Vascular; Nifedipine; Potassium | 1990 |
Effect of positive inotropic agents on myosin isozyme population and mechanical activity of cultured rat heart myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bucladesine; Cardiotonic Agents; Cells, Cultured; Colforsin; Heart; Isoenzymes; Isoproterenol; Myocardial Contraction; Myocardium; Myosins; Ouabain; Phenylephrine; Prazosin; Propranolol; Rats | 1991 |
Effects of cyclic AMP-affecting agents on contractile reactivity of isolated mesenteric and renal resistance arteries of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Arteries; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pertussis Toxin; Pyridones; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Renal Circulation; Sodium Fluoride; Sympathectomy; Vascular Resistance; Vasodilator Agents; Virulence Factors, Bordetella | 1990 |
Relaxation response of isolated canine veins to agents that act on the adenylate cyclase-cyclic AMP system: further investigation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Colforsin; Cyclic AMP; Dogs; Female; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Papaverine; Veins | 1990 |
Ontogeny of the adenylate cyclase system in the pulmonary vascular smooth muscle of the fetal lamb.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Embryonic and Fetal Development; Female; Fetus; Guanosine Triphosphate; Isoproterenol; Muscle Development; Muscle, Smooth, Vascular; Pregnancy; Pulmonary Circulation; Receptors, Adrenergic, beta; Sheep; Sodium Fluoride; Stimulation, Chemical | 1991 |
Norepinephrine and iloprost improve barrier function of human endothelial cell monolayers: role of cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Electric Conductivity; Endothelium, Vascular; Fluorescent Antibody Technique; Horseradish Peroxidase; Humans; Iloprost; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Propranolol; Umbilical Arteries; Venae Cavae | 1991 |
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Isoproterenol; Male; Muscle Relaxation; Phosphodiesterase Inhibitors; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilation | 1991 |
Intracellular resistance in rat papillary muscle: interaction between cyclic AMP and calcium.
Topics: Animals; Calcium; Cell Communication; Colforsin; Cyclic AMP; Extracellular Space; Heart; Intercellular Junctions; Intracellular Fluid; Isoproterenol; Membrane Potentials; Papillary Muscles; Propranolol; Rats; Temperature | 1991 |
Effects of phosphodiesterase inhibitors on vasoactive intestinal peptide-induced relaxation of isolated guinea-pig trachea.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Papaverine; Phosphodiesterase Inhibitors; SRS-A; Trachea; Vasoactive Intestinal Peptide | 1991 |
Intracellular Na+ modulates the cAMP-dependent regulation of ion channels in the heart.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Heart Ventricles; Homeostasis; Ion Channels; Isoproterenol; Kinetics; Membrane Potentials; Membrane Proteins; Sodium | 1991 |
Isolation and characterization of rat submandibular intralobular ducts.
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Calcium; Cell Separation; Centrifugation, Density Gradient; Colforsin; Cyclic AMP; Epinephrine; Isoproterenol; Kallikreins; Male; Povidone; Rats; Rats, Inbred Strains; Silicon Dioxide; Submandibular Gland | 1991 |
Hypertrophy of isolated adult feline heart cells following beta-adrenergic-induced beating.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cardiomegaly; Cats; Cells, Cultured; Colforsin; Culture Techniques; Cyclic AMP; Heart; Heart Rate; Isoproterenol; Myocardial Contraction; Myocardium; Myofibrils; Nifedipine; Norepinephrine; Propranolol; Receptors, Adrenergic, beta | 1991 |
Comparison of the effects of milrinone and OPC 3911 with those of isoprenaline, forskolin and dibutyryl-cAMP in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bucladesine; Calcium; Colforsin; In Vitro Techniques; Isoproterenol; Male; Milrinone; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Functional insertion of the SV40 large T oncogene in cystic fibrosis intestinal epithelium. Characterization of CFI-3 cells.
Topics: Antigens, Polyomavirus Transforming; Base Sequence; Cell Line; Cell Transformation, Viral; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Humans; In Vitro Techniques; Intestinal Mucosa; Ionomycin; Isoproterenol; Membrane Proteins; Molecular Sequence Data; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels; Transfection; Vasoactive Intestinal Peptide | 1991 |
Regulation of endogenous chloride conductance in Xenopus oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bumetanide; Calcium; Chloride Channels; Colforsin; Cyclic AMP; Cytosol; Female; Iodides; Iodine Radioisotopes; Ion Channels; Isoproterenol; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; ortho-Aminobenzoates; Rubidium; Rubidium Radioisotopes; Thionucleotides; Xenopus laevis | 1991 |
Enhanced lipolysis in 3T3-L1 adipocytes following prolonged exposure to tolbutamide.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Cell Differentiation; Colforsin; Cycloheximide; Glycerol; Isoproterenol; Kinetics; Lipolysis; Mice; Tolbutamide | 1991 |
Region-specific regulation of preproenkephalin mRNA in cultured astrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Blotting, Northern; Brain; Cells, Cultured; Cerebral Cortex; Colforsin; Corpus Striatum; Enkephalins; Hypothalamus; Isoproterenol; Protein Precursors; Rats; RNA; RNA, Messenger | 1991 |
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Calcium Channel Blockers; Carbachol; Cell Differentiation; Cell Line; Colforsin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryo, Nonmammalian; Heart; Heart Rate; Isoproterenol; Membrane Potentials; Myocardium; Parasympathomimetics; Phenylephrine; Prazosin; Stem Cells; Sympathomimetics | 1991 |
Effects of 8-bromo-cyclic GMP on slow channel mediated action potentials of 3-days-old embryonic chick ventricle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Chick Embryo; Colforsin; Cyclic GMP; Heart Ventricles; Ion Channels; Isoproterenol; Ventricular Function | 1991 |
Stathmin phosphorylation is regulated in striatal neurons by vasoactive intestinal peptide and monoamines via multiple intracellular pathways.
Topics: Animals; Biogenic Amines; Colforsin; Corpus Striatum; Dopamine; Intracellular Membranes; Isoproterenol; Microtubule Proteins; Neurons; Phosphoproteins; Phosphorylation; Second Messenger Systems; Stathmin; Vasoactive Intestinal Peptide | 1992 |
Noradrenergic receptor mechanisms in neophobia.
Topics: Adenylyl Cyclases; Animals; Anxiety; Behavior, Animal; Clonidine; Colforsin; Dopamine beta-Hydroxylase; Environment; Isoproterenol; Male; Norepinephrine; Oxidopamine; Phenylephrine; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1992 |
Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Animals; Colforsin; Dogs; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Purkinje Fibers | 1991 |
Effect of castration and anatomical site on the plasma membrane structure and the activities of adenylate cyclase and 5'-nucleotidase in pig adipocytes.
Topics: 5'-Nucleotidase; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cholesterol; Colforsin; Isoproterenol; Male; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Orchiectomy; Phospholipids; Swine | 1991 |
Relationship between adenylate cyclase activity and regional myocardial energetics in experimental left ventricular hypertrophy.
Topics: Adenylyl Cyclases; Animals; Cardiomegaly; Colforsin; Coronary Circulation; Dogs; Energy Metabolism; Heart Ventricles; Hemodynamics; Isoproterenol; Myocardial Contraction; Myocardium; Oxygen Consumption | 1991 |
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Guanosine Triphosphate; Insulin; Isoproterenol; Lung; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptor, Insulin; Sodium Fluoride; Streptozocin | 1991 |
Hormone-sensitive adenylate cyclase system in lymphocytes from asthmatic patients: possible defects at the postreceptor sites.
Topics: Adenylyl Cyclases; Adolescent; Adult; Aged; Asthma; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta | 1991 |
Phorbol-ester-induced phosphorylation of the beta 2-adrenergic receptor decreases its coupling to Gs.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cloning, Molecular; Colforsin; Cricetinae; DNA Mutational Analysis; GTP-Binding Proteins; Isoproterenol; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptors, Adrenergic, beta; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Effect of isoproterenol on intracellular pH of the intercalated cells in the rabbit cortical collecting ducts.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acid-Base Equilibrium; Amiloride; Animals; Atenolol; Chlorides; Colforsin; Cytoplasm; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Isoproterenol; Kidney Tubules, Collecting; Rabbits; Receptors, Adrenergic, beta; Time Factors | 1991 |
Diabetes-induced changes in cardiac beta-adrenoceptor responsiveness: effects of aldose reductase inhibition with ponalrestat.
Topics: Aldehyde Reductase; Animals; Calcium; Colforsin; Diabetes Mellitus, Experimental; Dihydroalprenolol; Female; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Phthalazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Sensitization enhances the adenylyl cyclase responsiveness in alveolar macrophages. Changes induced at post-receptor level.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; Iodocyanopindolol; Isoproterenol; Macrophage Activation; Macrophages; Male; Ovalbumin; Pindolol; Pulmonary Alveoli; Signal Transduction; Timolol | 1991 |
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella | 1991 |
Synergistic activation of brain adenylate cyclase by calmodulin, and either GTP or catecholamines including dopamine.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Calmodulin; Catecholamines; Cerebral Cortex; Colforsin; Corpus Striatum; Dopamine; Drug Synergism; Egtazic Acid; Enzyme Activation; Guanosine Triphosphate; Intracellular Membranes; Isoproterenol; Kinetics; Rats; Synaptosomes | 1990 |
Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients.
Topics: Binding Sites; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Cystic Fibrosis; Dose-Response Relationship, Drug; Fibroblasts; Glycoconjugates; Humans; Isoproterenol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1990 |
Contraction of cardiac myocytes from noradrenaline-treated rats in response to isoprenaline, forskolin and dibutyryl cAMP.
Topics: Animals; Bucladesine; Calcium; Colforsin; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepinephrine; Rats | 1990 |
The interaction of adenosine analogues with cAMP-generating and cAMP-independent positive inotropic agents in rabbit left atrium.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Drug Interactions; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Phenylephrine; Phenylisopropyladenosine; Potassium Channels; Rabbits; Receptors, Purinergic; Virulence Factors, Bordetella | 1990 |
Regulation of postnatal beta-adrenergic receptor/adenylate cyclase development by prenatal agonist stimulation and steroids: alterations in rat kidney and lung after exposure to terbutaline or dexamethasone.
Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Binding Sites; Body Weight; Colforsin; Dexamethasone; Drug Synergism; Female; Isoproterenol; Kidney; Lung; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Terbutaline | 1990 |
Alterations in beta-adrenoceptor density on T-lymphocytes upon activation with interleukin-2 and phytohaemagglutinin.
Topics: Adenylyl Cyclases; Colforsin; Cyclic AMP; Down-Regulation; Drug Interactions; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Interleukin-2; Isoproterenol; Kinetics; Lymphocyte Activation; Phytohemagglutinins; Protein Kinase C; Receptors, Adrenergic, beta; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Pseudomonas exotoxin A prevents beta-adrenoceptor-induced upregulation of Gi protein alpha-subunits and adenylyl cyclase desensitization in rat heart muscle cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; ADP Ribose Transferases; Adrenergic beta-Antagonists; Animals; Bacterial Toxins; Cells, Cultured; Colforsin; Exotoxins; GTP-Binding Proteins; Heart; Isoproterenol; Kinetics; Macromolecular Substances; Muscle, Smooth; Myocardium; NAD; Norepinephrine; Propanolamines; Pseudomonas aeruginosa Exotoxin A; Rats; Receptors, Adrenergic, beta; Virulence Factors | 1990 |
Neuropeptide Y and somatostatin inhibit stimulated cyclic AMP production in rabbit ciliary processes.
Topics: Animals; Ciliary Body; Colforsin; Cyclic AMP; Isoproterenol; Male; Neuropeptide Y; Octreotide; Rabbits; Somatostatin; Vasoactive Intestinal Peptide | 1990 |
Hormone inhibition of adenylyl cyclase. Differences in the mechanisms for inhibition by hormones and G protein beta gamma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; GTP-Binding Proteins; Isoproterenol; Kinetics; Lymphoma; Macromolecular Substances; Mice; Models, Biological; Somatostatin | 1990 |
The promoter of the human parathyroid hormone gene contains a functional cyclic AMP-response element.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Deoxyribonuclease I; Gene Expression Regulation; Genes; Humans; Isoproterenol; Molecular Sequence Data; Parathyroid Hormone; Promoter Regions, Genetic; Rats; Regulatory Sequences, Nucleic Acid; Somatostatin; Transcription, Genetic; Transfection | 1990 |
Effect of oxygen tension on catecholamine-induced formation of cAMP and on swelling of carp red blood cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Carps; Colforsin; Cyclic AMP; Epinephrine; Erythrocytes; Female; In Vitro Techniques; Isoproterenol; Kinetics; Norepinephrine; Oxygen; Partial Pressure; Receptors, Adrenergic, beta | 1990 |
Reduction of beta-adrenoceptor function by oxidative stress in the heart.
Topics: Adrenergic beta-Agonists; Animals; Benzene Derivatives; Bucladesine; Catecholamines; Cell Membrane; Colforsin; Coronary Disease; Free Radicals; Heart Atria; Heart Ventricles; Isoproterenol; Male; Rats; Rats, Inbred Strains; Terbutaline | 1990 |
Diastolic dysfunction in hypertrophic cardiomyopathy. Effect on active force generation during systole.
Topics: Adult; Aged; Caffeine; Calcium; Cardiomyopathy, Hypertrophic; Colforsin; Diastole; Female; Hemodynamics; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Strophanthidin; Systole; Verapamil | 1991 |
Reduced basal and stimulated (isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimer's disease correlated with histopathological changes.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Colforsin; Female; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Male; Postmortem Changes; Reference Values | 1991 |
Lack of presynaptic modulation by isoprenaline of 3H-noradrenaline release from rabbit isolated ear artery.
Topics: Animals; Arteries; Autonomic Fibers, Postganglionic; Colforsin; Ear, External; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phentolamine; Phosphodiesterase Inhibitors; Propranolol; Pyrimidines; Rabbits; Tritium; Yohimbine | 1991 |
Neuropeptide Y and peptide YY inhibit lipolysis in human and dog fat cells through a pertussis toxin-sensitive G protein.
Topics: Adenosine Deaminase; Adipose Tissue; Adult; Animals; Cell Membrane; Cells, Cultured; Colforsin; Dogs; Epinephrine; Fatty Acids, Nonesterified; Gastrointestinal Hormones; Glycerol; GTP-Binding Proteins; Humans; Isoproterenol; Kinetics; Lipolysis; Male; Neuropeptide Y; Peptide YY; Peptides; Pertussis Toxin; Virulence Factors, Bordetella | 1990 |
G-protein-linked serotonin receptors in mouse kidney exhibit identical properties to 5-HT1b receptors in brain.
Topics: Alkylation; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Colforsin; Ethylmaleimide; GTP-Binding Proteins; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Kidney; Male; Mice; Mice, Inbred BALB C; Pindolol; Receptors, Serotonin | 1990 |
Gs alpha mediates epidermal growth factor-elicited stimulation of rat cardiac adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antibodies; Carbachol; Colforsin; Epidermal Growth Factor; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Immune Sera; Isoproterenol; Kinetics; Male; Membrane Proteins; Molecular Sequence Data; Molecular Weight; Myocardium; Oligopeptides; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1990 |
Forskolin as an activator of adenylate cyclase complex of differentiating erythroid bone-marrow cells.
Topics: Adenylyl Cyclases; Anemia; Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Membrane; Colforsin; Enzyme Activation; Erythroid Precursor Cells; Erythropoietin; GTP-Binding Proteins; Isoproterenol; Rabbits | 1990 |
The effects of androgens on the regulation of lipolysis in adipose precursor cells.
Topics: Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Dihydrotestosterone; Glycerol; Insulin; Isoproterenol; Lipolysis; Male; Metribolone; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stem Cells; Testosterone | 1990 |
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.
Topics: Animals; Atrial Natriuretic Factor; Calcitonin; Cell Line; Cell-Free System; Colforsin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Isoproterenol; Mice; Microwaves; Nitroprusside; Skin; Subcellular Fractions; Thiocyanates | 1990 |
Endurance training, not acute exercise, differentially alters beta-receptors and cyclase in skeletal fiber types.
Topics: Adenylyl Cyclases; Animals; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Muscles; Organ Specificity; Physical Conditioning, Animal; Physical Exertion; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Succinate Cytochrome c Oxidoreductase | 1990 |
Identification of neurotransmitters by selective protection of postjunctional receptors.
Topics: Adenosine Triphosphate; Animals; Bucladesine; Colforsin; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Receptors, Neurotransmitter; Stomach; Vasoactive Intestinal Peptide | 1990 |
Deficiency of beta-adrenoceptor-mediated relaxation in suncus trachea.
Topics: Animals; Colforsin; Dihydroalprenolol; Eulipotyphla; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Membranes; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Adrenergic, beta; Species Specificity; Trachea | 1990 |
Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blotting, Western; Cell Membrane; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Niacin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic | 1990 |
Effect of the lectin concanavalin-A on calcium-regulated adenosine 3',5'-monophosphate accumulation in bovine parathyroid cells.
Topics: Animals; Calcium; Cattle; Colforsin; Concanavalin A; Cyclic AMP; Dinoprost; Dopamine; Fluorides; Ions; Isoproterenol; Methylglucosides; Osmolar Concentration; Parathyroid Glands | 1990 |
Regulation of cAMP levels by protein kinase C in C6 rat glioma cells.
Topics: Animals; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1990 |
Partial characterization of cyclic AMP-dependent protein kinases in guinea-pig lung employing the synthetic heptapeptide substrate, kemptide. In vitro sensitivity of the soluble enzyme to isoprenaline, forskolin, methacholine and leukotriene D4.
Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Chromatography, DEAE-Cellulose; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoenzymes; Isoproterenol; Lung; Magnesium; Male; Methacholine Chloride; Methacholine Compounds; Oligopeptides; Protein Kinase Inhibitors; Protein Kinases; Solubility; SRS-A | 1990 |
Regulation of proline-rich protein gene expression by cyclic AMP in primary cultures of hamster parotid glands.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Cycloheximide; Gene Expression Regulation; Isoproterenol; Kinetics; Male; Mesocricetus; Parotid Gland; Peptides; Proline; Proline-Rich Protein Domains; RNA, Messenger | 1990 |
In vivo administration of isoproterenol or forskolin during the light phase induces increases in the melatonin content of the Syrian hamster pineal gland without a rise in N-acetyltransferase activity.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Colforsin; Cricetinae; Isoproterenol; Lighting; Melatonin; Mesocricetus; Pineal Gland; Receptors, Adrenergic, beta | 1990 |
D-(-)-beta-hydroxybutyrate inhibits catecholamine-stimulated lipolysis and decreases beta-adrenoceptors' affinity in human fat cells but not in lymphomonocytes.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Adult; Bucladesine; Colforsin; Feedback; Humans; Hydroxybutyrates; In Vitro Techniques; Isoproterenol; Ketone Bodies; Leukocytes, Mononuclear; Lipolysis; Male; Middle Aged; Receptors, Adrenergic, beta | 1990 |
Decreased secretion due to a Ca2+ influx defect in frog peptic cells isolated with EGTA.
Topics: Acetylcholine; Animals; Bombesin; Calcium; Cell Membrane; Cell Separation; Colforsin; Cytochalasin B; Egtazic Acid; Esophagus; In Vitro Techniques; Isoproterenol; Kinetics; Microscopy, Electron; Pepsinogens; Rana catesbeiana; Receptors, Bombesin; Receptors, Muscarinic; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate | 1990 |
Neuropeptide Y binding and inhibition of cAMP accumulation in human neuroepithelioma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Carbachol; Cell Line; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Inositol Phosphates; Isoproterenol; Kinetics; Neuroectodermal Tumors, Primitive, Peripheral; Neuropeptide Y; Pertussis Toxin; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Inhibitory effects of clonidine and dopamine on adenylate cyclase of rabbit ciliary processes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Ciliary Body; Clonidine; Colforsin; Dopamine; In Vitro Techniques; Isoproterenol; Rabbits; Receptors, Adrenergic, alpha | 1990 |
Age-related deficit in beta receptor stimulation of cAMP binding in blood vessels.
Topics: Aging; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes.
Topics: Acetylcholine; Action Potentials; Animals; Binding Sites; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Phorbol Esters; Potassium; Potassium Channels; Protein Kinase C; Ventricular Function | 1990 |
In vitro beta-adrenergic stimulation of lymphocytes induces the release of immunoreactive beta-endorphin.
Topics: beta-Endorphin; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Isoproterenol; Isoquinolines; Kinetics; Lymphocytes; Protein Kinase Inhibitors; Receptors, Adrenergic, beta | 1990 |
Adrenergic and cholinergic interaction in central ventilatory control.
Topics: Acetylcholine; Animals; Atropine; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Medulla Oblongata; Propanolamines; Receptors, Adrenergic; Receptors, Cholinergic; Respiration; Respiratory Center; Second Messenger Systems; Yohimbine | 1990 |
Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Membrane; Colforsin; Down-Regulation; Humans; Isoproterenol; Kinetics; Molecular Sequence Data; Mutation; Protein Conformation; Receptors, Adrenergic, beta; Restriction Mapping; Transfection; Tyrosine | 1990 |
Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Binding, Competitive; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Humans; Isoproterenol; Neuroblastoma; Neuropeptide Y; Peptide YY; Peptides; Pertussis Toxin; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1990 |
Role of beta-adrenoceptor-adenylate cyclase system in the developmental decrease in sensitivity to isoprenaline in foetal and neonatal rat heart.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Colforsin; Dihydroalprenolol; Enzyme Activation; Female; Fetus; Heart; Heart Rate; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
The beta-agonist, isoprenaline, stimulates renin release from cultured nephroblastoma cells.
Topics: Bucladesine; Cell Division; Colforsin; Humans; Isoproterenol; Kidney Neoplasms; Renin; Tumor Cells, Cultured; Wilms Tumor | 1990 |
Evidence for the compartmentation of the enzymes of cyclic AMP metabolism.
Topics: Cell Compartmentation; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Organic Chemicals; Phosphodiesterase Inhibitors; Phosphorylase a; Phosphorylases; Pyrrolidinones; Rolipram | 1990 |
Protein kinase A and/or C inhibitors potentiate isoproterenol-induced cyclic AMP accumulation in intact human lymphocytes.
Topics: Alprostadil; Colforsin; Cyclic AMP; Drug Synergism; Humans; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Lymphocytes; Phorbol Esters; Pindolol; Protein Kinase C; Protein Kinase Inhibitors | 1990 |
Whole-cell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guinea Pigs; Heart Ventricles; Ion Channel Gating; Isoproterenol; Myocardium; Phosphorylation; Signal Transduction | 1990 |
Desensitization of vasopressin sensitive adenylate cyclase by vasopressin and phorbol esters.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Arginine Vasopressin; Cell Line; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Angiotensin; Receptors, Vasopressin | 1990 |
Regulation of platelet-activating factor receptor and platelet-activating factor receptor-mediated biological responses by cAMP in rat Kupffer cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Isoproterenol; Kinetics; Kupffer Cells; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2 | 1990 |
Epithelium, contractile tone, and responses to relaxing agonists in canine bronchi.
Topics: Acetylcholine; Animals; Bronchi; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Epithelium; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Serotonin | 1990 |
The effect of essential fatty acid deficiency on the adrenergic activation of glycogenolysis in rat hepatocytes.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Glucagon; Isoproterenol; Kinetics; Liver; Liver Glycogen; Melitten; Phenylephrine; Phosphorylase a; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reference Values | 1990 |
Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Female; Fetal Resorption; Isoproterenol; Kidney; Myocardium; Nicotine; Pindolol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Up-Regulation | 1990 |
Beta-adrenergic receptor regulation, through cyclic AMP, of nerve growth factor expression in rat cortical and cerebellar astrocytes.
Topics: Animals; Astrocytes; Cerebellum; Cerebral Cortex; Colforsin; Cyclic AMP; Gene Expression Regulation; Isoproterenol; Nerve Growth Factors; Phenoxybenzamine; Propranolol; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Second Messenger Systems | 1990 |
Induction of type II iodothyronine 5'-deiodinase and mitochondrial uncoupling protein in brown adipocytes differentiated in cell culture.
Topics: Adipose Tissue, Brown; Animals; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Iodide Peroxidase; Ion Channels; Isoproterenol; Kinetics; Membrane Proteins; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Proteins; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Uncoupling Protein 1 | 1990 |
Inhibition of FSH-stimulated cAMP accumulation and progesterone production by mono(2-ethylhexyl) phthalate in rat granulosa cell cultures.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Granulosa Cells; Isoproterenol; Progesterone; Proteins; Rats; Rats, Inbred F344; Time Factors | 1990 |
Regulation of beta-adrenergic responses during in vitro differentiation of mouse erythroleukemia cells.
Topics: Animals; Catecholamines; Cell Membrane; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Erythroid Precursor Cells; Interphase; Isoproterenol; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1990 |
Mechanism of acetylcholine-induced inhibition of Ca current in bullfrog atrial myocytes.
Topics: Acetylcholine; Action Potentials; Adenylyl Cyclase Inhibitors; Animals; Calcium; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1990 |
Nonreceptor-mediated responses of adenylate cyclase in membranes from liver, muscle, and white and brown adipose tissue of obese (fa/fa) and lean (Fa/) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Liver; Muscles; Norepinephrine; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Adrenergic, beta | 1990 |
Effects of beta-adrenergic receptor activation, cholera toxin and forskolin on human natural killer cell function.
Topics: Adenosine Diphosphate Ribose; Calcimycin; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Membrane Proteins; NAD; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1990 |
Forskolin but not isoprenaline increases sodium current from frog cardiac myocytes.
Topics: Animals; Colforsin; Heart; In Vitro Techniques; Isoproterenol; Membrane Potentials; Rana esculenta; Sodium Channels; Tetrodotoxin | 1990 |
Actions of forskolin and isoprenaline on the separated myometrial layers of the guinea-pig uterus: influence of ovarian steroids and pregnancy.
Topics: Animals; Colforsin; Diestrus; Electric Stimulation; Estradiol; Estrogens; Female; Guinea Pigs; Isoproterenol; Myometrium; Pregnancy; Pregnancy, Animal; Progesterone | 1990 |
Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline.
Topics: Airway Resistance; Animals; Atropine; Blood Platelets; Bombesin; Bronchodilator Agents; Colforsin; Dopamine; Epinephrine; Guinea Pigs; Histamine; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Platelet Activating Factor; Propranolol; Rabbits; Vagotomy; Vagus Nerve | 1990 |
Muscarinic cholinergic receptor mediated inhibitory transduction of adenylate cyclase activity in subcellular fractions from rat heart: improved detection in sodium phosphate buffer.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Enzyme Stability; Imidazoles; Isoproterenol; Male; Microsomes; Myocardium; Phosphates; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
Adenylate cyclase activities of vascular smooth muscle in early and established DOCA/salt hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calmodulin; Colforsin; Desoxycorticosterone; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic | 1990 |
Inhibitory effects of neuropeptide Y on adenylate cyclase of rabbit ciliary processes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Ciliary Body; Clonidine; Colforsin; Isoproterenol; Neuropeptide Y; Rabbits; Vasoactive Intestinal Peptide | 1990 |
Effects of adenosine and analogs on adenylate cyclase activity in cultured bovine aortic endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Isoproterenol; Muscle, Smooth, Vascular; Vasodilator Agents | 1990 |
Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Dinoprostone; Isoproterenol; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Rats; Transforming Growth Factors; Tumor Cells, Cultured | 1990 |
Changes in cytosolic CA2+ and contraction induced by various stimulants and relaxants in canine tracheal smooth muscle.
Topics: Animals; Benzofurans; Calcium; Carbachol; Colforsin; Cytosol; Dogs; Fura-2; Isoproterenol; Muscle Contraction; Muscle, Smooth; Phorbol Esters; Potassium; Trachea; Verapamil | 1990 |
Effects of isoproterenol on histamine release induced from monodispersed guinea-pig lung cells by different secretagogues.
Topics: Animals; Antigens; Bucladesine; Calcimycin; Calcium; Colforsin; Diterpenes; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Lung; Ovalbumin; Tetradecanoylphorbol Acetate | 1985 |
Relation between cyclic adenosine monophosphate and prostaglandin output by dispersed cells from human amnion and decidua.
Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Amnion; Bucladesine; Calcimycin; Cholera Toxin; Colforsin; Cyclic AMP; Decidua; Diterpenes; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Prostaglandins E; Prostaglandins F; Stimulation, Chemical; Trifluoperazine | 1985 |
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine | 1985 |
Muscarinic cholinergic inhibition of beta-adrenergic stimulation of phospholamban phosphorylation and Ca2+ transport in guinea pig ventricles.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Biological Transport; Calcium; Calcium-Binding Proteins; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardial Contraction; Myocardium; Phosphorus Radioisotopes; Phosphorylation; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1985 |
cAMP- and beta-adrenergic-stimulated chloride-dependent Ca2+ secretion in frog skin.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Biological Transport; Calcium; Chlorides; Colforsin; Cyclic AMP; Electric Conductivity; Female; Furosemide; Isoproterenol; Parathyroid Hormone; Rana pipiens; Skin; Stimulation, Chemical; Sympathomimetics; Thionucleotides; Vasopressins | 1985 |
Forskolin induces supersensitivity of the amylase secretory response of rat parotid tissue.
Topics: Amylases; Animals; Colchicine; Colforsin; Concanavalin A; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Parotid Gland; Rats; Rats, Inbred Strains; Strychnine; Vinblastine | 1985 |
Hormone secretagogues increase cytosolic calcium by increasing cAMP in corticotropin-secreting cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Isoproterenol; Mice; Pituitary Gland; Secretory Rate; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1985 |
Augmentation of isoproterenol-stimulated tissue cyclic AMP level by cholinergic agonists in rat parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Oxotremorine; Parotid Gland; Phentolamine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains | 1985 |
Augmentation of cholinergic-mediated amylase release by forskolin in mouse parotid gland.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic GMP; Drug Synergism; Guanosine; Hydroxylamine; Hydroxylamines; Isoproterenol; Mice; Nitroprusside; Parasympathomimetics; Parotid Gland | 1985 |
Effect of phosphodiesterase inhibitors on Sertoli cell refractoriness: reversal of the impaired androgen aromatization.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Estrogens; Follicle Stimulating Hormone; Isoproterenol; Male; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, FSH; Sertoli Cells | 1986 |
A novel type of cardiac calcium channel in ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; Electric Conductivity; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Potentials; Nifedipine; Ventricular Function | 1986 |
Effect of cyclic AMP on collagen production by corneal fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Collagen; Cornea; Cyclic AMP; Fibroblasts; Isoproterenol; Receptors, Adrenergic, beta | 1986 |
1,25-Dihydroxyvitamin D3 and adenosine 3',5'-monophosphate synergistically promote differentiation of a monocytic cell line.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Colforsin; Complement C5; Complement C5a; Cyclic AMP; Dinoprostone; Drug Synergism; Humans; Isoproterenol; Lymphoma; Monocytes; Prostaglandins E; Receptor, Anaphylatoxin C5a; Receptors, Complement | 1986 |
Endothelium-independent linkage of parathyroid hormone receptors of rat vascular tissue with increased adenosine 3',5'-monophosphate and relaxation of vascular smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium; Isoproterenol; Male; Membrane Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Papaverine; Parathyroid Hormone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Teriparatide | 1986 |
Cyclic adenosine 3',5'-monophosphate mediates beta-receptor actions of noradrenaline in rat hippocampal pyramidal cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenine; Adenylyl Cyclase Inhibitors; Animals; Calcium; Colforsin; Cyclic AMP; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Isoproterenol; Neurons; Norepinephrine; Potassium; Rats | 1986 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate | 1986 |
Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Electrophysiology; Female; Isoproterenol; Oocytes; Potassium; Progesterone; Xenopus laevis | 1986 |
On the mechanism of muscarinic inhibition of the cardiac Ca current.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Action Potentials; Animals; Calcium; Colforsin; Cyclic AMP; Female; Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Male; Perfusion; Pertussis Toxin; Protein Kinases; Virulence Factors, Bordetella | 1986 |
Carbachol inhibits electrophysiological effects of cyclic AMP in ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cell Separation; Colforsin; Cyclic AMP; Electrophysiology; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Myocardium; Time Factors | 1986 |
Effects of forskolin alone and in combination with isoproterenol on antigen-induced histamine release from guinea-pig minced lung.
Topics: Animals; Antigens; Colforsin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Lung; Ovalbumin | 1986 |
Prostacyclin production by isolated rat adipocytes: evidence for cyclic adenosine 3',5'-monophosphate-dependent and independent mechanisms and for a selective effect of insulin.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adipose Tissue; Adrenergic beta-Antagonists; Angiotensin II; Animals; Colforsin; Cyclic AMP; Dexamethasone; Epoprostenol; Insulin; Isoproterenol; Male; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; Bucladesine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Iodocyanopindolol; Isoproterenol; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Pindolol; Receptors, Adrenergic, beta; Serotonin | 1986 |
Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure.
Topics: 1-Methyl-3-isobutylxanthine; Caffeine; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Heart Failure; Humans; Isoproterenol; Milrinone; Myocardial Contraction; Myocardium; Pyridones; Stimulation, Chemical; Strophanthidin | 1987 |
Elevation of cAMP in cultured mesangial cells diminishes vasopressin-stimulated increases of phosphate uptake and 32P-specific activity in ATP but has no effect on phosphoinositide metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Isoproterenol; Phosphates; Phosphatidylinositols; Vasopressins | 1987 |
Catecholamine stimulation of androgen production by rat Leydig cells. Interactions with luteinizing hormone and luteinizing hormone-releasing hormone.
Topics: 1-Methyl-3-isobutylxanthine; Androgens; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; Isoproterenol; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Rats; Rats, Inbred Strains | 1986 |
Parathyroid hormone-induced changes in cyclic nucleotide levels during relaxation of the rabbit [correction of rat] aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parathyroid Hormone; Rabbits | 1987 |
Activation and desensitization of glycolysis by stimulation of adenylate cyclase in rat reticulocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Glucosephosphates; Glycolysis; Isoproterenol; Male; Rats; Rats, Inbred Strains; Reticulocytes; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical | 1987 |
Effect of dietary lipids on inotropic responses of isolated rat left atrium: attenuation of maximal responses by an unsaturated fat diet.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Dietary Fats; Epinephrine; Fatty Acids, Unsaturated; Female; Heart Atria; Isoproterenol; Myocardial Contraction; Norepinephrine; Phenylephrine; Pregnancy; Rats; Rats, Inbred Strains | 1987 |
Enhanced cAMP accumulation after termination of cholinergic action in the heart.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Heart; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Myocardial Contraction; Myocardium; Parasympathomimetics; Pindolol; Receptors, Muscarinic | 1987 |
Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Ion Channels; Isoproterenol; Male; Ouabain; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium; Submandibular Gland | 1987 |
Synergism between cellular messengers and agonist combinations in pepsinogen secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cell Communication; Colforsin; Cyclic AMP; Drug Synergism; Esophagus; Fluorescent Antibody Technique; Isoproterenol; L-Lactate Dehydrogenase; Pepsinogens; Protein Kinase C; Rana catesbeiana; Tetradecanoylphorbol Acetate | 1987 |
Action of forskolin on non-electrolyte permeability across the frog skin as compared to that of vasopressin and isoprenaline.
Topics: Animals; Antipyrine; Cell Membrane Permeability; Colforsin; Erythritol; In Vitro Techniques; Isoproterenol; Mannitol; Rana esculenta; Skin; Urea; Vasopressins | 1987 |
Effect of forskolin, isoproterenol and IBMX on angiotensin converting enzyme and cyclic AMP production by cultured bovine endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Isoproterenol; Kinetics; Peptidyl-Dipeptidase A; Theophylline | 1987 |
Effect of forskolin and acetylcholine on calcium current in single isolated cardiac myocytes.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Heart; Heart Ventricles; In Vitro Techniques; Ion Channels; Isoproterenol; Ranidae; Ventricular Function | 1987 |
A G protein directly regulates mammalian cardiac calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Leupeptins; Membrane Potentials; Phosphorylation; Thionucleotides; Ventricular Function | 1987 |
Regulation of human basophil and lung mast cell function by cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Basophils; Colforsin; Cyclic AMP; Histamine Release; Humans; Isoproterenol; Kinetics; Lung; Male; Mast Cells; Mice; Rats; Rats, Inbred Strains | 1988 |
[3H]protein secretion in rat parotid gland: substance P-beta-adrenergic synergism.
Topics: Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Parotid Gland; Proteins; Rats; Receptors, Adrenergic, beta; Secretory Rate; Substance P | 1987 |
Metabolic antagonism between insulin action and activators of adenylate cyclase in rat fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Enzyme Activation; Epinephrine; Fatty Acids; Female; Glycerol; Insulin; Isoproterenol; Lipids; Rats; Rats, Inbred Strains | 1987 |
Clonidine inhibits the isoproterenol-induced desensitization of the beta noradrenergic activated adenylate cyclase system in astrocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Astrocytes; Clonidine; Colforsin; Cyclic AMP; Enzyme Activation; Isoproterenol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Synergistic interactions between forskolin, isoprenaline and substance P as secretagogues in rat parotid glands.
Topics: alpha-Amylases; Animals; Colforsin; Cyclic AMP; Drug Synergism; Ethanolamines; In Vitro Techniques; Isoproterenol; Parotid Gland; Phosphatidylinositols; Rats; Substance P | 1987 |
Effect of isoproterenol and forskolin on amylase release from parotid tissue after chronic pilocarpine administration in rats following ligation removal.
Topics: Amylases; Animals; Colforsin; Isoproterenol; Male; Parotid Gland; Pilocarpine; Rats; Rats, Inbred Strains | 1987 |
Influence of androgenic status on the alpha 2/beta-adrenergic control of lipolysis in white fat cells: predominant alpha 2-antilipolytic response in testosterone-treated-castrated hamsters.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Male; Mesocricetus; Niacin; Orchiectomy; Phentolamine; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Testosterone | 1988 |
Inhibition of gonadotropin-responsive adenylate cyclase in MA-10 Leydig tumor cells by epidermal growth factor.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoproterenol; Leydig Cell Tumor; Luteal Cells; Mice; Rats; Tumor Cells, Cultured | 1988 |
Isoproterenol-induced desensitization of mucin release in isolated rat submandibular acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Glucosamine; Isoproterenol; Male; Mucins; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Submandibular Gland | 1988 |
Increased adenylate cyclase catalytic activity explains how estrogens "in vivo" promote lipolytic activity in rat white fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Epinephrine; Estradiol; Female; Isoproterenol; Kinetics; Lipolysis; Ovariectomy; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Relationships of secretagogue-induced cAMP accumulation and acid secretion in elutriated rat gastric parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyrine; Animals; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Fluorescence; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Isoproterenol; Male; Microscopy, Electron; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
On the mechanism of isoprenaline- and forskolin-induced depolarization of single guinea-pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Action Potentials; Albuterol; Animals; Colforsin; Cyclic AMP; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Metoprolol; Myocardium; Sodium; Temperature | 1988 |
A Ca2+-linked increase in coupled cAMP synthesis and hydrolysis is an early event in cholinergic and beta-adrenergic stimulation of parotid secretion.
Topics: Adrenergic beta-Agonists; Amylases; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Ethers; Ionomycin; Isoproterenol; Male; Octopamine; Parasympathomimetics; Parotid Gland; Potassium; Rats; Rats, Inbred Strains | 1988 |
Cyclic AMP-mediated stabilization of osteocalcin mRNA in rat osteoblast-like cells treated with parathyroid hormone.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium-Binding Proteins; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Osteoblasts; Osteocalcin; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Rats; RNA, Messenger; Teriparatide | 1988 |
The in vitro activation of cyclic AMP production by either forskolin or isoproterenol in the Syrian hamster pineal during the day is not accompanied by an increase in melatonin production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Isoproterenol; Kinetics; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Pineal Gland | 1988 |
Adrenergic modulation of the release of 5-hydroxytryptamine from the vascularly perfused ileum of the guinea-pig.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Colforsin; Guinea Pigs; Hydroxyindoleacetic Acid; Ileum; Isoproterenol; Male; Naphthyridines; Perfusion; Phosphodiesterase Inhibitors; Serotonin | 1988 |
Effect of vasoactive intestinal peptide on myocardial contractility and coronary blood flow in the dog: comparison with isoproterenol and forskolin.
Topics: Animals; Colforsin; Coronary Circulation; Coronary Vessels; Dogs; Heart Rate; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Oxygen Consumption; Vasoactive Intestinal Peptide | 1988 |
Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Calcitriol; Cholera Toxin; Colforsin; Dexamethasone; Isoproterenol; Kinetics; Osteoblasts; Osteopontin; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Rats; RNA, Messenger; Sialoglycoproteins; Teriparatide; Transcription, Genetic; Transforming Growth Factors; Tumor Cells, Cultured | 1989 |
A beta-adrenergic agonist modulates DR alpha gene transcription via enhanced cAMP levels in a glioblastoma multiforme line.
Topics: Bucladesine; Colforsin; Cyclic AMP; Glioblastoma; HLA-DR Antigens; Humans; Isoproterenol; Receptors, Adrenergic, alpha; RNA; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Cholinergic antagonism of beta-adrenergic stimulated action potentials and adenylate cyclase activity in rabbit ventricular cardiomyocytes.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bucladesine; Calcium; Colforsin; Heart; Isoproterenol; Male; Myocardium; Parasympathetic Nervous System; Rabbits; Receptors, Muscarinic | 1988 |
Modulation of the cardiac transient outward current by catecholamines.
Topics: Animals; Catecholamines; Colforsin; Cyclic AMP; Dogs; Heart Conduction System; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Potentials; Norepinephrine; Purkinje Fibers | 1989 |
Beta-adrenergic system is modified in compensatory pressure cardiac overload in rats: physiological and biochemical evidence.
Topics: Animals; Binding Sites; Cardiac Pacing, Artificial; Cardiomegaly; Colforsin; Coronary Circulation; Isoproterenol; Male; Myocardial Contraction; Perfusion; Pindolol; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |
Activation of the beta 2-adrenergic receptor promotes growth and differentiation in thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Differentiation; Cell Division; Cell Line; Colforsin; Cyclic AMP; DNA Replication; Humans; Iodides; Isoproterenol; Rats; Receptors, Adrenergic, beta; Thyroid Gland; Thyrotropin; Transfection | 1989 |
Multiple effects of ethanol on cardiac adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Ethanol; Female; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Male; Manganese; Myocardium; NAD; Pindolol; Rabbits; Receptors, Adrenergic, beta | 1989 |
A comparison of cyclic AMP signaling system in rat aortic myocytes in primary culture and aorta.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1989 |
Beta-adrenergic relaxation of dog trachealis: contractile agonist-specific interaction.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adrenergic beta-Agonists; Animals; Bucladesine; Colforsin; Dogs; Histamine; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Serotonin; Trachea | 1989 |
Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Arginine Vasopressin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Kidney; Kidney Diseases, Cystic; Terbutaline | 1989 |
Glucagon-induced refractoriness of hepatocyte adenylate cyclase: comparison of homologous and heterologous components and evidence against a role of cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Isoproterenol; Liver; Male; Rats; Rats, Inbred Strains | 1989 |
Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; DNA; Fibroblasts; Gene Expression Regulation; Genes; Genetic Vectors; Homeostasis; Humans; Isoproterenol; Kinetics; Mutation; Phosphorylation; Receptors, Adrenergic, beta; RNA, Messenger; Theophylline; Transcription, Genetic; Transfection | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Inhibitory modulation by cAMP of isoproterenol-induced prostacyclin synthesis in rabbit heart.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclase Inhibitors; Animals; Blood Pressure; Colforsin; Cyclic AMP; Epoprostenol; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Quinolones; Rabbits; Thionucleotides | 1989 |
Studies of glucocorticoid enhancement of the capacity of hepatocytes to accumulate cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Glucagon; Glucocorticoids; Isoproterenol; Kinetics; Liver; Male; Methylprednisolone; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains | 1989 |
Aging of rat heart myocytes disrupts muscarinic receptor coupling that leads to inhibition of cAMP accumulation and alters the pathway of muscarinic-stimulated phosphoinositide hydrolysis.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Heart; Isoproterenol; Kinetics; Myocardium; Norepinephrine; Oxotremorine; Phosphatidylinositols; Rats; Receptors, Muscarinic; Time Factors | 1989 |
Modulation by intracellular Ca2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells.
Topics: Action Potentials; Animals; Calcium; Cesium; Colforsin; Cyclic AMP; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Rabbits; Sinoatrial Node; Tetradecanoylphorbol Acetate | 1989 |
Inhibitory effects of beta-adrenergic stimulants on increased vascular permeability caused by passive cutaneous anaphylaxis, allergic mediators, and mediator releasers in rats.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Ascaris; Capillary Permeability; Colforsin; Cyclic AMP; Female; Histamine Release; Hypersensitivity; Immunoglobulin E; Isoproterenol; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Skin; Theophylline | 1989 |
Calmodulin-dependent adenylate cyclase activity in rat cerebral cortex: effects of divalent cations, forskolin and isoprenaline.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cations, Divalent; Cerebral Cortex; Colforsin; In Vitro Techniques; Isoproterenol; Magnesium; Male; Manganese; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |
New positive inotropic agent OPC-8212 modulates single Ca2+ channels in ventricular myocytes of guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium Channels; Cardiotonic Agents; Colforsin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Isoproterenol; Myocardium; Phosphorylation; Pyrazines; Quinolines | 1989 |
Cyclic nucleotide regulation of neurotransmission in guinea pig mesenteric artery.
Topics: Animals; Colforsin; Cyclic GMP; Electrophysiology; Guinea Pigs; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Nucleotides, Cyclic; Phorbol Esters; Protein Kinase C; Second Messenger Systems; Synaptic Transmission | 1989 |
Atherosclerosis and responses of human isolated coronary arteries to endothelium-dependent and -independent vasodilators.
Topics: Animals; Colforsin; Coronary Artery Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Molsidomine; Nitroglycerin; Rodentia; Vasodilator Agents | 1989 |
Role of the calcium-calmodulin system in the adenylate cyclase activity of vascular smooth muscle.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calcimycin; Calcium; Calmodulin; Colforsin; Edetic Acid; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Trifluoperazine | 1989 |
Autonomic regulation of delayed rectifier K+ current in mammalian heart involves G proteins.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Autonomic Nervous System; Colforsin; Electric Conductivity; Electrophysiology; GTP-Binding Proteins; Guinea Pigs; Heart; Isoproterenol; Pertussis Toxin; Potassium; Temperature; Virulence Factors, Bordetella | 1989 |
Studies on the mechanism of the decreased guanine nucleotide stimulatory effects on adenylate cyclase after adrenalectomy in rat adipocytes.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Cell Membrane; Cholera Toxin; Colforsin; GTP-Binding Proteins; Guanine Nucleotides; Isoproterenol; Male; Rats; Rats, Inbred Strains; Sodium Fluoride | 1989 |
Relaxation of human peripheral airway smooth muscle in vitro does not correlate with severity of chronic airflow limitation in vivo.
Topics: Adult; Aged; Bronchi; Chronic Disease; Colforsin; Female; Forced Expiratory Volume; Humans; Isoproterenol; Lung Diseases, Obstructive; Male; Methacholine Compounds; Middle Aged; Muscle Relaxation; Muscle, Smooth; Respiratory Function Tests | 1989 |
Effects of steroids on serotonin-N-acetyltransferase activity of pineals in organ culture.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Bucladesine; Cholera Toxin; Colforsin; Corticosterone; Dose-Response Relationship, Drug; Hydrocortisone; Indoles; Isoproterenol; Male; Melatonin; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred F344; Steroids; Tryptophan | 1989 |
Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships.
Topics: Animals; Arginine; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Potassium | 1989 |
Autonomic regulation of type 1 protein phosphatase in cardiac muscle.
Topics: Acetylcholine; Animals; Colforsin; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardium; Phosphoprotein Phosphatases; Receptors, Muscarinic; Sarcoplasmic Reticulum | 1989 |
Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Adrenocorticotropic Hormone; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Dexamethasone; In Vitro Techniques; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Reference Values; Sodium Fluoride; Vasoactive Intestinal Peptide | 1989 |
Monovalent ion enhancement of beta-adrenergic-stimulated adenylate cyclase activity in mouse parotid gland.
Topics: Adenylyl Cyclases; Animals; Brain; Chlorides; Colforsin; Drug Synergism; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Mice; Parotid Gland; Sodium; Thionucleotides | 1989 |
Inactivation of cyclic AMP-dependent taurine release from astroglia.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Isoproterenol; Kinetics; Neuroglia; Receptors, Adrenergic, beta; Taurine | 1989 |
Subacute noradrenergic agonist infusions in vivo increase Na+, K+-ATPase and ouabain binding in rat cerebral cortex.
Topics: Animals; Brain; Cerebral Cortex; Clonidine; Colforsin; Hydroxydopamines; Isoproterenol; Male; Norepinephrine; Ouabain; Oxidopamine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase | 1989 |
Glucocorticoids modify differentially dopamine- and prostaglandin E1-mediated cyclic AMP formation by the cultured human astrocytoma clone D384.
Topics: Adenylyl Cyclases; Alprostadil; Astrocytoma; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Dopamine; Glucocorticoids; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Protein Biosynthesis; Tumor Cells, Cultured | 1989 |
Augmentation by external Mg ions of beta-adrenoceptor-mediated actions in the longitudinal muscle of rat uterus.
Topics: Animals; Bucladesine; Colforsin; Electrophysiology; Female; In Vitro Techniques; Isoproterenol; Magnesium; Membrane Potentials; Muscle, Smooth; Ovariectomy; Papaverine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Uterus | 1989 |
Effect of colforsin on human neutrophil superoxide production and intracellular calcium mobilization.
Topics: Adult; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cytosol; Humans; In Vitro Techniques; Isoproterenol; Male; Neutrophils; Propranolol; Superoxides; Time Factors | 1989 |
Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Cerebral Cortex; Chlorides; Colforsin; Cyclic AMP; Isoproterenol; Male; Osmolar Concentration; Rats; Solutions; Stimulation, Chemical; Time Factors | 1989 |
Autonomic regulation of a chloride current in heart.
Topics: Acetylcholine; Action Potentials; Adenylyl Cyclases; Animals; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Electric Conductivity; Enzyme Activation; Guinea Pigs; Heart; Isoproterenol; Membrane Potentials; Membrane Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Ventricular Function | 1989 |
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
Topics: Aging; Animals; Aorta; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Timolol | 1989 |
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Colforsin; Diabetes Mellitus, Experimental; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |
Synergistic potentiation of polyphosphoinositide breakdown by adenylate cyclase coupled receptors in human endothelial cells.
Topics: Adenylyl Cyclases; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Drug Synergism; Endothelium, Vascular; Histamine; Humans; Isoproterenol; Phosphatidylinositols; Receptors, Cyclic AMP; Signal Transduction | 1989 |
Absence of alpha-2 adrenergic effects on cAMP production in a genital tract smooth muscle cell line.
Topics: Animals; Cell Line, Transformed; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Genital Neoplasms, Male; Isoproterenol; Leiomyosarcoma; Male; Muscle, Smooth; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Vas Deferens | 1989 |
Isoproterenol, DBcAMP, and forskolin inhibit cardiac sodium current.
Topics: Animals; Atenolol; Bucladesine; Colforsin; Electric Conductivity; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Sodium Channels; Ventricular Function | 1989 |
Decreased bioactivity of the guanine nucleotide-binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Autoradiography; Blotting, Northern; Cardiomyopathies; Cholera Toxin; Colforsin; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Isoproterenol; Male; Manganese; Mesocricetus; Myocardium; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1989 |
Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway.
Topics: Animals; Atrial Function; Calcium Channels; Carbachol; Cells, Cultured; Colforsin; GTP-Binding Proteins; Guinea Pigs; Heart; Isoproterenol; Kinetics; Membrane Potentials; Signal Transduction | 1989 |
Agonist regulation of beta-adrenergic receptor mRNA. Analysis in S49 mouse lymphoma mutants.
Topics: Animals; Cell Line; Colforsin; Gene Expression Regulation; Genes; Isoproterenol; Lymphoma; Mice; Mutation; Nucleic Acid Hybridization; Receptors, Adrenergic, beta; RNA, Messenger | 1989 |
Evidence for the presence of serotonin receptors negatively coupled to adenylate cyclase in the rabbit iris-ciliary body.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Ciliary Body; Colforsin; Cyclic AMP; Iris; Isoproterenol; Pertussis Toxin; Rabbits; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tryptamines; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1989 |
Islet-activating protein inhibits the beta-adrenergic receptor facilitation elicited by gamma-aminobutyric acidB receptors.
Topics: Adenosine Diphosphate Ribose; Animals; Baclofen; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Synergism; GTP-Binding Proteins; Hippocampus; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Virulence Factors, Bordetella | 1989 |
Contractile force and intracellular Ca2+ during relaxation of canine tracheal smooth muscle.
Topics: Acetylcholine; Aequorin; Animals; Calcium; Carbachol; Colforsin; Dogs; In Vitro Techniques; Indicators and Reagents; Isometric Contraction; Isoproterenol; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Potassium; Serotonin; Sodium-Potassium-Exchanging ATPase; Trachea | 1989 |
The effects of p21N-ras expression in NIH-3T3 cells upon cyclic AMP metabolism.
Topics: Animals; Binding Sites; Bucladesine; Cell Division; Cell Line; Cell Line, Transformed; Colforsin; Cyclic AMP; Dexamethasone; Genes, ras; Isoproterenol; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptors, Adrenergic, beta | 1989 |
Role of cyclic AMP in proliferation of lung tissue in organ culture.
Topics: Animals; Bucladesine; Cell Division; Colforsin; Cyclic AMP; DNA Replication; Isoproterenol; Lung; Male; Organ Culture Techniques; Rats; Rats, Inbred Strains; Thymidine | 1989 |
Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels.
Topics: Adult; Aged; Calcium Channel Blockers; Colforsin; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Milrinone; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Splanchnic Circulation; Vasodilator Agents | 1989 |
Maintenance of proximal and distal cell functions in SV40-transformed tubular cell lines derived from rabbit kidney cortex.
Topics: Animals; Arginine Vasopressin; Biological Transport; Calcitonin; Cell Division; Cell Line; Cell Transformation, Viral; Colforsin; Cyclic AMP; Hydrogen-Ion Concentration; Hydrolases; Immunoenzyme Techniques; Isoproterenol; Kidney Cortex; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Methylglucosides; Microscopy, Electron; Parathyroid Hormone; Rabbits; Simian virus 40 | 1989 |
Adenosine receptor coupling to adenylate cyclase of rat ventricular myocyte membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Colforsin; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardium; Peptidyl-Dipeptidase A; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Beta-adrenergic stimulation of phagocytosis in the unicellular eukaryote Paramecium aurelia.
Topics: Alprenolol; Animals; Binding Sites; Bucladesine; Colforsin; Dansyl Compounds; Isoproterenol; Norepinephrine; Paramecium; Phagocytosis; Phorbol Esters; Propranolol; Receptors, Adrenergic, beta | 1989 |
Multiple signaling pathways of histamine H2 receptors. Identification of an H2 receptor-dependent Ca2+ mobilization pathway in human HL-60 promyelocytic leukemia cells.
Topics: Calcium; Calcium Channel Blockers; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Histamine H2; Signal Transduction; Tumor Cells, Cultured | 1989 |
Regulation of force and intracellular calcium transients by cyclic AMP generated by forskolin, MDL 17,043 and isoprenaline, and its modulation by muscarinic receptor agents: a novel mechanism for accentuated antagonism.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Dogs; Enoximone; Female; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Receptors, Muscarinic | 1989 |
Effects of the putative antagonists phaclofen and delta-aminovaleric acid on GABAB receptor biochemistry.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Cerebral Cortex; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Kinetics; Male; Proteins; Radioligand Assay; Rats; Receptors, GABA-A | 1989 |
Increase in Gs and cyclic AMP generation in HIT cells. Evidence that the 45-kDa alpha-subunit of Gs has greater functional activity than the 52-kDa alpha-subunit.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Islets of Langerhans; Isoproterenol; Kinetics; Macromolecular Substances; Mesocricetus; Molecular Weight; NAD; Pertussis Toxin; Virulence Factors, Bordetella | 1989 |
Chronic norepinephrine elicits desensitization by uncoupling the beta-receptor.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dogs; Drug Tolerance; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Ventricles; Hemodynamics; Isoproterenol; Norepinephrine; Organ Size; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Ventricular Function | 1989 |
Supersensitivity of beta-adrenoceptor coupled adenylate cyclase in pulmonary tissue of the spontaneously hypertensive rat.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Guanylyl Imidodiphosphate; Hypertension; Isoproterenol; Lung; Male; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta | 1989 |
Reduced cAMP-signal transduction in postmortem hippocampus of demented old people.
Topics: Adenylyl Cyclases; Aged; Alzheimer Disease; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guanylyl Imidodiphosphate; Hippocampus; Humans; Isoproterenol; Male; Middle Aged; Signal Transduction | 1989 |
The local anaesthetic benzyl alcohol attenuates the alpha 2-adrenoceptor-mediated inhibition of human platelet adenylate cyclase activity when stimulated by prostaglandin E1, but not that stimulated by forskolin.
Topics: Adenylyl Cyclases; Alprostadil; Anesthetics, Local; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Blood Platelets; Cell Membrane; Colforsin; Humans; Isoproterenol; Kinetics; Receptors, Adrenergic, alpha; Sodium Fluoride | 1989 |
An increase in myocardial beta-adrenoceptors to compensate for postischaemic dysfunction following coronary micro-embolisation in dogs.
Topics: Animals; Colforsin; Convalescence; Coronary Disease; Dogs; Embolism; Female; Hemodynamics; Isoproterenol; Lactates; Male; Microspheres; Myocardium; Norepinephrine; Receptors, Adrenergic, beta | 1989 |
Comparison of Mg, Mn, and Co ions affecting the beta-adrenoceptor-mediated membrane response in the guinea-pig taenia caeci.
Topics: Animals; Cecum; Cobalt; Colforsin; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Magnesium; Male; Manganese; Membrane Potentials; Muscle, Smooth; Papaverine; Receptors, Adrenergic, beta | 1989 |
Interactive effects of isoprenaline, forskolin and acetylcholine on Ca2+ current in frog ventricular myocytes.
Topics: Acetylcholine; Animals; Calcium Channels; Colforsin; Drug Interactions; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardium; Rana esculenta | 1989 |
Beta-adrenergic modulation of transient inward current in guinea-pig cardiac myocytes. Evidence for regulation of Ca2(+)-release from sarcoplasmic reticulum by a cyclic AMP dependent mechanism.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Isoproterenol; Male; Myocardium; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum | 1989 |
Modulation of the delayed rectifier potassium current in frog cardiomyocytes by beta-adrenergic agonists and magnesium.
Topics: Action Potentials; Animals; Calcium Channels; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Isoproterenol; Magnesium; Potassium; Potassium Channels; Rana catesbeiana; Time Factors | 1989 |
Chronic somatostatin treatment induces enhanced forskolin-stimulated cAMP accumulation in wild-type S49 mouse lymphoma cells but not in protein kinase-deficient mutants.
Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Isoproterenol; Lymphoma; Mice; Protein Kinases; Somatostatin; Tumor Cells, Cultured | 1989 |
Inhibition of calcium of beta adrenoceptor mediated cAMP responses in isolated bovine corneal epithelial cells.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cattle; Cells, Cultured; Colforsin; Cornea; Cyclic AMP; Epithelium; Isoproterenol | 1989 |
Participation of cyclic adenosine monophosphate and beta-adrenergic receptors in the facilitatory effect of noradrenaline on the response of cultured cerebellar neurons to glutamate.
Topics: Action Potentials; Animals; Bucladesine; Cells, Cultured; Cerebellum; Chick Embryo; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Isoproterenol; Norepinephrine; Receptors, Adrenergic, beta; Second Messenger Systems; Theophylline | 1989 |
Alpha 1- and beta-adrenergic agents cause synergistic stimulation of the iodothyronine deiodinase in rat brown adipocytes.
Topics: Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Imidazoles; Iodide Peroxidase; Isoproterenol; Male; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Heterogeneity of beta-adrenoceptor in canine veins: comparison among the facial, portal and saphenous veins.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Bucladesine; Catecholamines; Colforsin; Dogs; Ethanolamines; Face; Isoproterenol; Male; Portal Vein; Procaterol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Saphenous Vein; Veins | 1989 |
1,25-Dihydroxycholecalciferol and glucocorticosteroid regulation of adenylate cyclase in an osteoblast-like cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcitriol; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Glucocorticoids; Guanylyl Imidodiphosphate; Isoproterenol; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Time Factors; Triamcinolone Acetonide | 1985 |
beta-Adrenergic induced K+ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Aminobenzoates; Aminopyridines; Animals; Atropine; Calcimycin; Colforsin; Cyclic AMP; Diterpenes; Female; Isoproterenol; Oocytes; Phosphodiesterase Inhibitors; Potassium; Receptors, Adrenergic, beta; Tetraethylammonium Compounds; Xenopus laevis | 1985 |
Involvement of calcium in the release of immunoreactive beta-endorphin-like peptide from dispersed cells of the neurointermediate lobe of the rat pituitary gland.
Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Endorphin; Bucladesine; Calcimycin; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Endorphins; In Vitro Techniques; Isoproterenol; Pituitary Gland; Rats; Theophylline; Verapamil | 1985 |
Regulation of lipid metabolism by dipyridamole and adenosine antagonists in rat adipocytes.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Cells, Cultured; Colforsin; Dipyridamole; Enzyme Activation; Female; Isoproterenol; Lipid Metabolism; Lipolysis; Rats; Rats, Inbred Strains; Xanthines | 1989 |
Effects of calcitonin gene-related peptide on the adenylate cyclase system in cultured rat skeletal muscle cells.
Topics: Adenylyl Cyclases; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Female; Isoproterenol; Male; Muscles; Rats; Rats, Inbred Strains; Sodium Fluoride | 1989 |
Altered thyroid status regulates the adipocyte A1 adenosine receptor-adenylate cyclase system.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Biological Assay; Cell Membrane; Colforsin; Fluorides; Hyperthyroidism; Isoproterenol; Male; Manganese; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triiodothyronine | 1989 |
Comparative in vitro myocardial inotropic effects and in vivo hemodynamic effects of forskolin and isoproterenol in young lambs.
Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Colforsin; Heart Rate; Hemodynamics; Isoproterenol; Myocardial Contraction; Sheep | 1989 |
Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Female; Fetus; Glucagon; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parasympatholytics; Phorbol 12,13-Dibutyrate; Pyrroles; Rats; Rats, Inbred Strains; Xanthines | 1989 |
Secretion of corticotropin-releasing factor from cultured rat hypothalamic cells: effects of catecholamines.
Topics: Animals; Animals, Newborn; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Hypothalamus; Isoproterenol; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Emergence of beta adrenergic-responsive hepatic glycogenolysis in male rats during post-maturational aging.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Epinephrine; Glucagon; Glucose; Glycogen; Isoproterenol; Liver; Male; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1987 |
Matrix assembly sites for exogenous fibronectin are decreased on human fibroblasts after treatment with agents which increase intracellular cAMP.
Topics: Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Epinephrine; Extracellular Matrix; Fibroblasts; Fibronectins; Humans; Isoproterenol; Norepinephrine; Receptors, Fibronectin; Receptors, Immunologic; Skin | 1987 |
Micro-electrode studies on the effects of exogenous cyclic adenosine monophosphate on active sodium transport in frog skin.
Topics: Action Potentials; Amiloride; Animals; Arginine Vasopressin; Biological Transport, Active; Colforsin; Cyclic AMP; Electric Conductivity; In Vitro Techniques; Isoproterenol; Ranidae; Skin Physiological Phenomena; Sodium; Theophylline; Time Factors | 1987 |
Differential effects of chronic administration of desipramine on the cyclic AMP response in cortical slices and membranes in the rat.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Desipramine; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Isoproterenol; Male; Manganese; Membranes; Rats; Rats, Inbred Strains; Sodium Fluoride | 1987 |
Cyclic AMP signal transduction in posttraumatic stress disorder.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Aluminum; Aluminum Chloride; Aluminum Compounds; Blood Platelets; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Humans; Isoproterenol; Lymphocytes; Middle Aged; Receptors, Adrenergic, beta; Stress Disorders, Post-Traumatic | 1987 |
Alterations in cardiac beta-adrenoceptor responsiveness and adenylate cyclase system by congestive heart failure in dogs.
Topics: 5'-Nucleotidase; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Dihydroalprenolol; Dobutamine; Dogs; Guanylyl Imidodiphosphate; Heart Failure; Hemodynamics; In Vitro Techniques; Isoproterenol; Kinetics; Manganese; Manganese Compounds; Myocardium; Norepinephrine; Nucleotidases; Receptors, Adrenergic, beta | 1987 |
Stimulation and inhibition of lipolysis in isolated rat adipocytes: evidence for age-related changes in responses to forskolin and PGE1.
Topics: Adipose Tissue; Aging; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains | 1987 |
Effect of sodium butyrate on S-100 protein levels and the cAMP response.
Topics: Animals; Butyrates; Butyric Acid; Colforsin; Cyclic AMP; Glial Fibrillary Acidic Protein; Glioma; Humans; Intermediate Filament Proteins; Isoproterenol; Radioimmunoassay; Rats; S100 Proteins; Theophylline; Tumor Cells, Cultured | 1987 |
Expression of rat mRNA coding for hormone-stimulated adenylate cyclase in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Membrane; Colforsin; Female; Isoproterenol; Membrane Potentials; Microinjections; Oocytes; Ovarian Follicle; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Transformation, Genetic; Tumor Cells, Cultured; Xenopus laevis | 1987 |
In vivo and in vitro models of demyelinating disease: activation of the adenylate cyclase system influences JHM virus expression in explanted rat oligodendrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Astrocytes; Bucladesine; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Colforsin; Demyelinating Diseases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Models, Biological; Murine hepatitis virus; Neuroglia; Oligodendroglia; Protein Kinases; Rats; Virus Replication | 1987 |
Evidence for adenylate cyclase-coupled A1-adenosine receptors on ventricular cardiomyocytes from adult rat and dog heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dogs; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1987 |
Protein kinases induce isoproterenol desensitization of beta-adrenoceptor-coupled adenylate cyclase system: significance of receptor occupancy.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Bucladesine; Colforsin; Cyclic AMP; Dihydroalprenolol; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reticulocytes; Theophylline | 1987 |
Age-related and testicular regression-induced changes in adenosine 3',5'-monophosphate responses in cultured hamster Sertoli cells.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Aging; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Follicle Stimulating Hormone; Isoproterenol; Male; Mesocricetus; Pertussis Toxin; Reference Values; Sertoli Cells; Testis; Time Factors; Virulence Factors, Bordetella | 1988 |
Adenylate cyclase in the primate corpus luteum during chorionic gonadotropin treatment simulating early pregnancy: homologous versus heterologous desensitization.
Topics: Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Guanylyl Imidodiphosphate; Isoproterenol; Macaca mulatta; Pregnancy; Pregnancy, Animal; Progesterone; Prostaglandins E; Receptors, LH | 1988 |
Tissue and species specific responsiveness of developing avian and murine secondary palates to prostaglandin E2 stimulation.
Topics: Animals; Cell Differentiation; Chick Embryo; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Female; Isoproterenol; Mice; Mice, Inbred C57BL; Palate; Prostaglandins E; Species Specificity | 1988 |
Short-term incubation of cardiac myocytes with isoprenaline has no effect on heparin-releasable or cellular lipoprotein lipase activity.
Topics: Animals; Colforsin; Cyclic AMP; Heart; Heparin; In Vitro Techniques; Isoproterenol; Lipoprotein Lipase; Male; Myocardium; Phosphorylase a; Rats | 1987 |
Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Imidazoles; Isoproterenol; Mice; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1988 |
Isolated neuronal growth cones from developing rat forebrain possess adenylate cyclase activity which can be augmented by various receptor agonists.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Colforsin; Dopamine; Frontal Lobe; Isoproterenol; Rats; Receptors, Neurotransmitter; Subcellular Fractions; Synapses; Vasoactive Intestinal Peptide | 1988 |
Selective amplification of luteinizing hormone by adenosine in rat luteal cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cholera Toxin; Colforsin; Corpus Luteum; Cyclic AMP; Drug Interactions; Ethers; Female; Ionomycin; Isoproterenol; Kinetics; Luteal Cells; Luteinizing Hormone; Rats | 1988 |
Cyclic nucleotides depress action potentials in cultured aortic smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1987 |
Activation of an S6 kinase from rat astroglial cells by cAMP.
Topics: Animals; Astrocytes; Bucladesine; Colforsin; Cyclic AMP; Enzyme Activation; Insulin; Isoproterenol; Kinetics; Mitogens; Phosphorylation; Protein Kinases; Rats; Ribosomal Protein S6 Kinases | 1988 |
The vasorelaxant effects of milrinone and other vasodilators are attenuated by ouabain.
Topics: Animals; Aorta, Thoracic; Colforsin; Drug Interactions; Female; Guinea Pigs; Hydralazine; In Vitro Techniques; Isoproterenol; Isoquinolines; Isosorbide; Milrinone; Nitroprusside; Ouabain; Pyridones; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Vasodilator Agents; Verapamil | 1988 |
Evidence that parathyroid hormone-mediated calcium transport in rat brain synaptosomes is independent of cyclic adenosine monophosphate.
Topics: Adenylyl Cyclases; Animals; Biological Transport; Brain; Calcimycin; Calcium; Cell Membrane; Colforsin; Cyclic AMP; Dogs; In Vitro Techniques; Isoproterenol; Kidney Cortex; Parathyroid Hormone; Rats; Synaptosomes | 1988 |
Noradrenergic enhancement of long-term potentiation at mossy fiber synapses in the hippocampus.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Hippocampus; Isoproterenol; Male; Nerve Fibers; Neural Inhibition; Norepinephrine; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synapses; Time Factors | 1988 |
Estrogen reduces beta-adrenoceptor-mediated cAMP production and the concentration of the guanyl nucleotide-regulatory protein, Gs, in rabbit myometrium.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; GTP-Binding Proteins; Isoproterenol; Myometrium; Ovariectomy; Progesterone; Prostaglandins E; Rabbits; Receptors, Adrenergic, beta | 1988 |
[Functional changes induced by adrenergic purinergic receptors and adenyl cyclase activators in the isolated heart].
Topics: Adenosine; Amrinone; Animals; Colforsin; Coronary Circulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Perfusion; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Purinergic | 1987 |
Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; Electron Transport Complex IV; Isoproterenol; Male; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Sodium Fluoride | 1988 |
Impaired beta-adrenergic receptor and normal postreceptor responsiveness in congestive heart failure.
Topics: Adenylyl Cyclases; Blood Pressure; Colforsin; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Myocardial Contraction; Receptors, Adrenergic, beta; Regression Analysis | 1988 |
Effects of colforsin, trequinsin and isoprenaline on norepinephrine-induced contractions and cyclic nucleotide levels of isolated vascular tissue.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation Inhibitors; Rabbits; Tetrahydroisoquinolines | 1988 |
Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Fatty Acids; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Effect of Na-K adenosinetriphosphatase activity on relaxation of canine tracheal smooth muscle.
Topics: Animals; Calcium Channel Blockers; Colforsin; Dinoprostone; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Potassium; Prostaglandins E; Sodium-Potassium-Exchanging ATPase; Trachea | 1988 |
Does the hydrolysis of inositol phospholipids lead to the opening of voltage operated Ca2+ channels in guinea-pig ileum? Studies with fluoride ions and caffeine.
Topics: Animals; Caffeine; Calcium; Carbachol; Colforsin; Cyclic AMP; Fluorides; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols | 1988 |
Permissive action of glucocorticoids on catecholamine-induced lipolysis: direct "in vitro" effects on the fat cell beta-adrenoreceptor-coupled-adenylate cyclase system.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dexamethasone; Estrenes; GTP-Binding Proteins; Isoproterenol; Lipid Mobilization; Male; Manganese; Mifepristone; Rats; Receptors, Adrenergic, beta | 1988 |
Phorbol ester modulation of cyclic AMP accumulation in a primary culture of rat aortic smooth muscle cells.
Topics: Adenylate Cyclase Toxin; Animals; Aorta; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Muscle, Smooth, Vascular; Pertussis Toxin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Desensitization by external Na of the cyclic AMP-dependent Na+/H+ antiporter in trout red blood cells.
Topics: Absorption; Animals; Carrier Proteins; Colforsin; Cyclic AMP; Erythrocytes; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Nystatin; Ouabain; Sodium; Sodium-Hydrogen Exchangers; Trout; Water | 1988 |
Nonspecific supersensitivity induced by reserpine in guinea pig cardiac ventricle tissue.
Topics: Animals; Colforsin; Guinea Pigs; Heart; Heart Ventricles; Imidazoles; Impromidine; Isoproterenol; Male; Norepinephrine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Reserpine | 1988 |
Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Astrocytes; Brain; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Enzyme Induction; Iodide Peroxidase; Isoproterenol; Kinetics; Norepinephrine; Rats | 1988 |
Forskolin inhibition of glucose transport in bone cell cultures through a cAMP-independent mechanism.
Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Biological Transport; Bone and Bones; Cell Line; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Deoxyglucose; Dinoprostone; Glucose; Humans; Isoproterenol; Parathyroid Hormone; Prostaglandins E | 1988 |
Desensitization of myocardial but not coronary VIP receptor-mediated responses in dogs.
Topics: Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart; Isoproterenol; Oxygen; Oxygen Consumption; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Reference Values; Vasoactive Intestinal Peptide | 1988 |
Cyclic AMP second-messenger signal amplification in depression.
Topics: Adult; Aged; Antidepressive Agents; Colforsin; Cyclic AMP; Depressive Disorder; Female; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Male; Middle Aged; Prostaglandins E; Receptors, Cyclic AMP; Sex Factors; Sleep Initiation and Maintenance Disorders | 1988 |
Differential inhibitory effects of forskolin, isoproterenol, and dibutyryl cyclic adenosine monophosphate on phosphoinositide hydrolysis in canine tracheal smooth muscle.
Topics: Animals; Bucladesine; Colforsin; Dogs; Histamine; Hydrolysis; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Trachea | 1988 |
Forskolin potentiates isoproterenol induced beta adrenoceptor desensitization in intact human lymphocytes.
Topics: Colforsin; Cyclic AMP; Drug Synergism; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Receptors, Adrenergic, beta | 1988 |
The role of zinc status in altered cardiac adenylate cyclase activity in diabetic rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Sodium Fluoride; Zinc | 1988 |
Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinases; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Differential effects of fluoride on adenylate cyclase activity and guanine nucleotide regulation of agonist high-affinity receptor binding.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Anura; Cell Membrane; Cells, Cultured; Colforsin; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Yohimbine | 1988 |
Homologous vs. heterologous desensitization of the adenylate cyclase system in heart cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Myocardium; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta | 1988 |
Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Carbachol; Cattle; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Fura-2; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Tetradecanoylphorbol Acetate; Trachea; Virulence Factors, Bordetella | 1988 |
The effect of hCG on cyclic AMP in rabbit ciliary processes.
Topics: Adenylyl Cyclases; Animals; Chorionic Gonadotropin; Ciliary Body; Colforsin; Cyclic AMP; Isoproterenol; Male; Rabbits; Rats; Testis | 1987 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
Possible induction of fatty acid cyclooxygenase in mouse osteoblastic cells (MC3T3-E1) by cAMP.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cholera Toxin; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Induction; Epinephrine; Immunosorbent Techniques; Isoproterenol; Mice; Norepinephrine; Osteoblasts; Phenylephrine; Propranolol; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, beta | 1988 |
The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
PGE2-induced cyclic AMP accumulation in human CD4+ T cells is strongly enhanced during the CD2-mediated activatory process.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Isoproterenol; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1988 |
Evidence for pharmacologically distinct subsets of GABAB receptors.
Topics: Animals; Baclofen; Binding, Competitive; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Propylamines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Ca2+ not cyclic AMP mediates the fluid secretory response to isoproterenol in the rat mandibular salivary gland: whole-cell patch-clamp studies.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Submandibular Gland | 1988 |
Stimulation of nerve growth factor mRNA content in C6 glioma cells by a beta-adrenergic receptor and by cyclic AMP.
Topics: Animals; Blotting, Northern; Cell Line; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Molecular Weight; Nerve Growth Factors; Nucleic Acid Hybridization; Phenoxybenzamine; Propranolol; Receptors, Adrenergic, beta; RNA, Messenger | 1988 |
Effects of isoproterenol on Cl transport in rat submandibular salivary-gland acini.
Topics: Animals; Biological Transport, Active; Bucladesine; Chlorides; Colforsin; Isoproterenol; Male; Rats; Rats, Inbred Strains; Submandibular Gland | 1988 |
Quantitative differences in the cyclic AMP-lipolysis relationships for isoproterenol and forskolin.
Topics: Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Isoproterenol; Lipolysis; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline | 1988 |
Effect of forskolin on beta-adrenergic hyporesponsiveness in skin.
Topics: Animals; Colforsin; Cyclic AMP; Female; Isoproterenol; Keratinocytes; Mice; Mice, Inbred C3H; Psoriasis; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1988 |
Physiological approach of beta receptor coupling to adenylate cyclase in rat airways: ontogenical modification and functional antagonism.
Topics: Adenylyl Cyclases; Age Factors; Airway Resistance; Animals; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Rats; Receptors, Adrenergic, beta; Trachea | 1985 |
Somatostatin-14 and somatostatin-28 pretreatment down-regulate somatostatin-14 receptors and have biphasic effects on forskolin-stimulated cyclic adenosine, 3',5'-monophosphate synthesis and adrenocorticotropin secretion in mouse anterior pituitary tumor
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Kinetics; Mice; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Somatostatin; Somatostatin; Somatostatin-28 | 1985 |
Acute change in the cyclic AMP content of rat mammary acini in vitro. Influence of physiological and pharmacological agents.
Topics: Adrenergic Agonists; Animals; Colforsin; Cyclic AMP; Dihydroalprenolol; Female; Humans; Imidazoles; Isoproterenol; Ligands; Mammary Glands, Animal; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1985 |
Hormonal regulation of adenylate cyclase in the stria vascularis of the mouse.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cochlea; Colforsin; Cyclic AMP; Epinephrine; Guanosine Triphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Norepinephrine; Propranolol; Receptors, Adrenergic; Stria Vascularis; Vasopressins | 1985 |
Characterization of beta-adrenergic binding sites on rodent Leydig cells.
Topics: Adrenergic beta-Antagonists; Androgens; Animals; Binding, Competitive; Cell Separation; Cells, Cultured; Colforsin; Isoproterenol; Kinetics; Leydig Cells; Luteinizing Hormone; Male; Mice; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Regulation of neurotensin release from canine enteric primary cell cultures.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cells, Cultured; Colforsin; Dogs; Epinephrine; Ileum; Intestinal Mucosa; Isoproterenol; Nerve Tissue Proteins; Neuropeptides; Neurotensin; Parasympathomimetics; Radioimmunoassay; Somatostatin; Time Factors | 1986 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsin; Fenoterol; Hydrocortisone; In Vitro Techniques; Indomethacin; Isoproterenol; Muscle Contraction; Muscle Relaxation; Norepinephrine; Phenylephrine; Quinacrine; Receptors, Adrenergic, beta; Stereoisomerism; Swine; Theophylline | 1986 |
An unconventional response of adenylate cyclase to morphine and naloxone in the chicken during early development.
Topics: Adenylyl Cyclases; Age Factors; Animals; Chick Embryo; Colforsin; Enzyme Activation; Isoproterenol; Morphine; Naloxone; Neurotransmitter Agents; Norepinephrine; Sodium Fluoride | 1986 |
Beta-adrenoceptor-mediated modulation of calcium ionophore activated polymorphonuclear leucocytes.
Topics: Adrenergic beta-Agonists; Adult; Bucladesine; Calcimycin; Colforsin; Humans; In Vitro Techniques; Isoproterenol; Luminescent Measurements; Middle Aged; Neutrophils; Oxidation-Reduction; Propranolol; Receptors, Adrenergic, beta | 1986 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Chlorides; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mathematics; Pertussis Toxin; Phorbol Esters; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Desensitization in rat parotid to beta-adrenergic agonists and counteracting effects of forskolin are conserved in membrane and detergent-solubilized adenylate cyclase catalyst activity.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Membranes; Parotid Gland; Rats; Rats, Inbred Strains | 1986 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
Effects of forskolin, isoproterenol and lithium ions on leucophores of a teleost, Oryzias latipes: evidence for involvement of adenylate cyclase in pigment-dispersion response.
Topics: Adenylyl Cyclases; Animals; Chromatophores; Colforsin; Cyprinodontiformes; Denervation; Isoproterenol; Lithium; Oryzias; Pigments, Biological | 1987 |
Beta-adrenergic agonists and cyclic AMP decrease intracellular resting free-calcium concentration in ileum smooth muscle.
Topics: Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth | 1987 |
Characterization of adenylate cyclase in human retinal pigment epithelial cells in vitro.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Humans; Isoproterenol; Pigment Epithelium of Eye; Prostaglandins; Receptors, Adrenergic, beta | 1987 |
Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Binding Proteins; Carrier Proteins; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Myofibrils; Phosphorylation; Rabbits; Troponin; Troponin I | 1988 |
Airway hyperreactivity.
Topics: Airway Resistance; Animals; Colforsin; Guinea Pigs; Humans; Isoproterenol | 1988 |
Carboxyl terminal domain of Gs alpha specifies coupling of receptors to stimulation of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Mice; Receptors, Adrenergic, beta; Recombinant Proteins; Somatostatin; Structure-Activity Relationship | 1988 |
Effect of high doses of somatostatin on adenylate cyclase activity in peripheral mononuclear leukocytes from normal subjects and from acute leukemia patients.
Topics: Acute Disease; Adenylyl Cyclases; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoproterenol; Leukemia; Leukocytes, Mononuclear; Somatostatin | 1988 |
Molecular mechanism of beta-adrenergic receptor blockers with intrinsic sympathomimetic activity.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Celiprolol; Colforsin; Cyclic AMP; Drug Synergism; Isoproterenol; Lymphoma; Pindolol; Propanolamines; Propranolol; Sympathomimetics; Tumor Cells, Cultured | 1988 |
Effects of neurotransmitters on astrocyte glycogen stores in vitro.
Topics: Animals; Animals, Newborn; Astrocytes; Bucladesine; Carbachol; Cells, Cultured; Cerebral Cortex; Colforsin; Dihydroalprenolol; Glycogen; Isoproterenol; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Muscarinic; Receptors, Serotonin; Reserpine; Serotonin | 1988 |
Hormone-sensitive adenylate cyclase of prolactin-producing rat pituitary adenoma (GH4C1) cells: molecular organization.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Dinoprostone; Hormones; Isoproterenol; Kinetics; Pituitary Neoplasms; Prolactinoma; Somatostatin; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1988 |
Effect of thyroid status on catecholamine stimulation of thyroxine 5'-deiodinase in brown adipocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue, Brown; Alprenolol; Animals; Catecholamines; Colforsin; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Isoproterenol; Kinetics; Male; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains | 1989 |
Circadian rhythm of the in vitro stimulation of adenylate cyclase in rat heart tissue.
Topics: Adenylyl Cyclases; Animals; Circadian Rhythm; Colforsin; Enzyme Activation; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains | 1989 |
Modulation by Leu-enkephalin of peptide release from perifused neurointermediate pituitary. II. Inhibition of calcium-mediated secretion of alpha-MSH and beta-endorphin.
Topics: Animals; beta-Endorphin; Calcimycin; Calcium; Colforsin; Corticotropin-Releasing Hormone; Endorphins; Enkephalin, Leucine; Isoproterenol; Male; Melanocyte-Stimulating Hormones; Pituitary Gland, Posterior; Potassium; Rats; Rats, Inbred Strains; Veratridine | 1986 |
[Effect of forskolin, isoprenaline and propranolol on spontaneous contractions of the isolated atrium of guinea pigs].
Topics: Animals; Colforsin; Drug Interactions; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Propranolol | 1985 |
Adenylate cyclase activity in rat corpora lutea evidence for a rapid development of the regulatory Ns-protein.
Topics: Adenylyl Cyclases; Age Factors; Animals; Colforsin; Corpus Luteum; Female; Fluorides; Gonadotropins, Equine; Guanylyl Imidodiphosphate; Isoproterenol; Luteinizing Hormone; Models, Biological; Rats; Rats, Inbred Strains; Viral Nonstructural Proteins; Viral Proteins | 1986 |
The rat testicular A1 adenosine receptor-adenylate cyclase system.
Topics: Adenosine; Adenylyl Cyclases; Affinity Labels; Animals; Colforsin; Guanylyl Imidodiphosphate; Iodine Radioisotopes; Isoproterenol; Male; Phenylisopropyladenosine; Photochemistry; Rats; Rats, Inbred Strains; Receptors, Purinergic; Solubility; Testis | 1986 |
NAD+-mediated stimulation of adenylate cyclase in cardiac membranes.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Arginine; Cell Membrane; Colforsin; Enzyme Activation; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Manganese; Myocardium; NAD; NADP; Niacinamide; Rabbits; Sodium Fluoride | 1987 |
Beta-adrenergic stimulation of adenosine-3',5'-monophosphate (c-AMP) accumulation and of prolactin and growth hormone secretion in rat anterior pituitary cell cultures.
Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Dexamethasone; Diterpenes; Female; Growth Hormone; Isoproterenol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
cAMP metabolism and lipolysis in brown adipocytes of hamsters consuming a cafeteria diet.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; Cricetinae; Cyclic AMP; Diet; Diterpenes; Isoproterenol; Lipolysis; Male | 1985 |
Inhibitory effect of atrial natriuretic factor on adenylate cyclase activity in adrenal cortical membranes.
Topics: Adenylyl Cyclase Inhibitors; Adrenal Cortex; Adrenocorticotropic Hormone; Alprostadil; Animals; Atrial Natriuretic Factor; Cell Membrane; Colforsin; Diterpenes; Dopamine; Isoproterenol; Muscle Proteins; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Role of cyclic AMP protein kinase in decreased arterial cyclic AMP responsiveness in hypertension.
Topics: Animals; Aorta, Thoracic; Arteries; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Hypertension; Isoenzymes; Isoproterenol; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction | 1985 |
Rate-limiting steps in isoproterenol and forskolin stimulated lipolysis.
Topics: Animals; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Glycerol; Isoproterenol; Lipolysis; Protein Kinases; Rats; Rats, Inbred Strains | 1985 |
Cyclic nucleotides and contractility of isolated soleus muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscles; Terbutaline | 1985 |
Altered binding properties of beta-adrenergic receptors and lack of coupling to adenylate cyclase in P815 mastocytoma cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dihydroalprenolol; Diterpenes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Neoplasm Proteins; Receptors, Adrenergic, beta; Sarcoma, Experimental; Sodium Fluoride | 1985 |
beta-Adrenergic receptors and adenylate cyclase activity in murine lymphoid cell lines.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; B-Lymphocytes; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Lymphocytes; Lymphoma; Mice; Receptors, Adrenergic, beta; T-Lymphocytes | 1985 |
The effect of relaxin on cyclic adenosine 3',5'-monophosphate concentrations in rat myometrial cells in culture.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Female; Guinea Pigs; Isoproterenol; Myometrium; Myosin-Light-Chain Kinase; Protein Kinases; Rats; Rats, Inbred Strains; Relaxin; Swine | 1985 |
Inhibitory effect of methacholine on drug-induced relaxation, cyclic AMP accumulation, and cyclic AMP-dependent protein kinase activation in canine tracheal smooth muscle.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Dogs; Enzyme Activation; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Protein Kinases; Trachea | 1985 |
Regulation of cyclic AMP metabolism by muscarinic cholinergic receptors.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Bacterial Toxins; Calcium; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Humans; Isoproterenol; Kinetics; Mice; Molecular Weight; Oxotremorine; Phosphodiesterase Inhibitors; Prostaglandins E; Receptors, Adrenergic, beta; Receptors, Muscarinic; Virulence Factors, Bordetella | 1985 |
Regulation of cyclic AMP accumulation in lymphoid cells.
Topics: Adenylyl Cyclases; Adult; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; GTP-Binding Proteins; Humans; Isoproterenol; Lymphocytes; Mice; Receptors, Adrenergic, beta; Temperature | 1985 |
Heritability of forskolin and hormone-stimulated adenylate cyclase activity in human lymphocytes.
Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Colforsin; Diterpenes; Enzyme Activation; Female; Humans; Isoproterenol; Lymphocytes; Male; Pregnancy; Prostaglandins E; Receptors, Adrenergic, beta; Twins, Monozygotic | 1985 |
Corticotropin-peptide regulation of intracellular cyclic AMP production in cortical neurons in primary culture.
Topics: Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Isoproterenol; Melanocyte-Stimulating Hormones; Mice; Microscopy, Electron, Scanning; Neurons; Peptide Fragments; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1985 |
Externalization of beta-adrenergic receptors promoted by myocardial ischemia.
Topics: 5'-Nucleotidase; Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Coronary Disease; Diterpenes; Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Intracellular Membranes; Isoproterenol; Male; Nucleotidases; Receptors, Adrenergic, beta; Sarcolemma | 1985 |
Comparison of cholinergic inhibition and beta-adrenergic stimulation of adenylate cyclase from rat and guinea-pig hearts: effects of guanine nucleotides and monovalent cations.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Cations, Monovalent; Chlorides; Colforsin; Cytosol; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Lithium; Lithium Chloride; Male; Myocardium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Sodium Fluoride; Tissue Distribution | 1985 |
The use of forskolin to investigate the site of cardiac beta-adrenoreceptor supersensitivity.
Topics: Animals; Colforsin; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Propranolol; Receptors, Adrenergic, beta; Reserpine; Temperature | 1985 |
A role for adenylate cyclase in the subsensitivity to isoproterenol during ontogenesis of the embryonic chick ventricle.
Topics: Adenylyl Cyclases; Animals; Chick Embryo; Chickens; Chlorides; Colforsin; Cyclic AMP; Dihydroalprenolol; Dose-Response Relationship, Drug; Drug Interactions; Guanylyl Imidodiphosphate; Heart; Isoproterenol; Kinetics; Magnesium; Manganese; Manganese Compounds; Muscle Contraction; Myocardium; Receptors, Adrenergic, beta; Sodium Fluoride | 1985 |
Involvement of cAMP in modulation of noradrenaline release in the human pulmonary artery.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adult; Aged; Colforsin; Cyclic AMP; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthyridines; Norepinephrine; Pulmonary Artery | 1985 |
Uncoupling between beta-adrenoceptors and adenylate cyclase in dog ischemic myocardium.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Colforsin; Coronary Disease; Dogs; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Membranes; Myocardium; Receptors, Adrenergic, beta; Sodium Fluoride; Vasoactive Intestinal Peptide | 1985 |
Corticotropin-releasing factor-induced adrenocorticotropin hormone release and synthesis is blocked by incorporation of the inhibitor of cyclic AMP-dependent protein kinase into anterior pituitary tumor cells by liposomes.
Topics: Adrenocorticotropic Hormone; Animals; Ceruletide; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Isoproterenol; Liposomes; Mice; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Protein Kinase Inhibitors; Protein Kinases; RNA, Messenger; Secretory Rate | 1985 |
Beta-adrenergic-stimulated adenylate cyclase activity in normal and EBV-transformed lymphocytes.
Topics: Adenylyl Cyclases; Cell Line; Cell Transformation, Viral; Colforsin; Cyclic AMP; Herpesvirus 4, Human; Iodocyanopindolol; Isoproterenol; Lymphocytes; Pindolol; Receptors, Adrenergic, beta | 1985 |
Lymphocyte protein kinase activity in cells from young and elderly men and women.
Topics: Adult; Aged; Aging; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Propranolol; Protein Kinases; Sex Factors | 1985 |
Relaxin affects the shape of rat myometrial cells in culture.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Female; Isoproterenol; Kinetics; Myometrium; Myosin-Light-Chain Kinase; Oxytocin; Protein Kinases; Rats; Rats, Inbred Strains; Relaxin | 1986 |
Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cobalt; Colforsin; Cyclic AMP; Enzyme Activation; Erythropoietin; Isoproterenol; Kinetics; Lactates; Lactic Acid; Liver; Mice; Oxygen | 1986 |
Inotropic, chronotropic and coronary vasodilator potency of forskolin.
Topics: Adenylyl Cyclases; Animals; Colforsin; Coronary Circulation; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Potassium; Vascular Resistance; Vasodilation | 1985 |
Expression of beta-adrenergic receptors in synchronous and asynchronous S49 lymphoma cells. II. Relationship between receptor number and response.
Topics: Adenylyl Cyclases; Alprenolol; Cell Cycle; Cell Line; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Receptors, Adrenergic, beta | 1986 |
The effects of phospholipase A2 on beta adrenoceptor function in isolated cardiac cells.
Topics: Animals; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dogs; Fatty Acids, Nonesterified; Female; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phospholipases; Phospholipases A; Phospholipases A2; Radioimmunoassay; Radioligand Assay; Receptors, Adrenergic, beta | 1985 |
[Effect of isoprenaline and the barium ion on the relaxation of the smooth muscle of the guinea pig trachea].
Topics: Animals; Barium; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Ions; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1985 |
The role of phospholipase in reduced beta-adrenergic responsiveness in experimental asthma.
Topics: Adenylyl Cyclases; Animals; Asthma; Colforsin; Cyclic AMP; Fatty Acids; Guinea Pigs; Isoproterenol; Lung; Male; Membrane Proteins; Phospholipases; Phospholipases A; Phospholipids; Receptors, Adrenergic, beta | 1986 |
Role of calcium ion in hormone-stimulated lipolysis.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; In Vitro Techniques; Isoproterenol; Kinetics; Lipid Mobilization; Male; Rats | 1986 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Relationship, Drug; Epithelium; Female; Guinea Pigs; Histamine; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Muscle Contraction; Nitroglycerin; Pindolol; Potassium; Receptors, Adrenergic, beta; Theophylline; Trachea | 1986 |
Vascular vasopressin receptors mediate inhibition of beta adrenergic receptor-induced cyclic AMP accumulation.
Topics: Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Muscle, Smooth, Vascular; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Vasopressin | 1986 |
Prostaglandin E2 inhibition of secretagogue-stimulated [14C]aminopyrine accumulation in rat parietal cells: a model for its mechanism of action.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Aminopyrine; Animals; Bucladesine; Carbon Radioisotopes; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; Histamine; In Vitro Techniques; Isoproterenol; Male; Models, Biological; Parasympathetic Nervous System; Parietal Cells, Gastric; Pertussis Toxin; Prostaglandins E; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1986 |
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Reduced chronotropic responsiveness of the heart in experimental uremia.
Topics: Adenylyl Cyclases; Animals; Blood Pressure; Cell Membrane; Colforsin; Heart; Heart Rate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sarcolemma; Time Factors; Uremia | 1986 |
Effects of relaxants on electrical and mechanical activities in the guinea-pig tracheal muscle.
Topics: Animals; Bucladesine; Colforsin; Epinephrine; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Norepinephrine; Terbutaline; Theophylline; Trachea | 1986 |
ATP-dependent calcium transport in rat parotid basolateral membrane vesicles. Modulation by agents which elevate cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Radioisotopes; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Male; Parotid Gland; Rats; Rats, Inbred Strains | 1986 |
Desensitization of adenosine receptor-mediated inhibition of lipolysis. The mechanism involves the development of enhanced cyclic adenosine monophosphate accumulation in tolerant adipocytes.
Topics: Adenosine Deaminase; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Colforsin; Cyclic AMP; Drug Tolerance; Fatty Acids, Nonesterified; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Time Factors; Triglycerides | 1986 |
Importance of calcium in renal renin release.
Topics: Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; DDT; Diltiazem; Epoprostenol; Gallic Acid; Isoproterenol; Juxtaglomerular Apparatus; Kidney; Kidney Cortex; Male; Rats; Renin; Renin-Angiotensin System; Stimulation, Chemical | 1986 |
Hormone and forskolin-stimulated cyclic AMP accumulation in human lymphocytes: reliability of longitudinal time measurements.
Topics: Adult; Alprostadil; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Sex Factors; Time Factors | 1986 |
Relationships between cyclic AMP levels and lipolysis in fat cells after isoproterenol and forskolin stimulation.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Lipolysis; Rats; Rats, Inbred Strains; Theophylline | 1986 |
Effects of prostaglandin E1, isoproterenol and forskolin on cyclic AMP levels and tension in rabbit aortic rings.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rabbits | 1986 |
Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart Atria; Heart Ventricles; Isoproterenol; Myocardium; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides | 1986 |
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitroprusside; Potassium; Trachea | 1986 |
Regulation of magnesium but not calcium transport by phorbol ester.
Topics: Animals; Biological Transport, Active; Calcium; Cell Line; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Magnesium; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
Effect of atriopeptin III on renin release in vitro.
Topics: Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Diltiazem; Gallic Acid; In Vitro Techniques; Isoproterenol; Kidney Cortex; Rats; Renin; Secretory Rate | 1986 |
Experimental model of anaphylaxis-induced beta-adrenergic blockade in the airways.
Topics: Alprostadil; Aminophylline; Anaphylaxis; Animals; Colforsin; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Receptors, Adrenergic, beta; Trachea | 1986 |
Fasting increases fat cell adenylate cyclase sensitivity to stimulatory agonists through enhanced ability of the stimulatory regulatory component Ns to dissociate.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cholera Toxin; Colforsin; Fasting; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Macromolecular Substances; Male; Manganese; Rats; Receptors, Adrenergic, beta | 1986 |
A re-evaluated role for cyclic AMP in uterine relaxation. Differential effect of isoproterenol and forskolin.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Isoproterenol; Kinetics; Myometrium; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Uterine Contraction | 1986 |
Adenosine receptors on human lymphocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Manganese; Neutrophils; Receptors, Purinergic; Theophylline; Vidarabine | 1986 |
Characteristics of the beta-adrenergic stimulation of adenylate cyclase activity in rat ventral prostate and its modulation by androgens.
Topics: Adenylyl Cyclases; Androgens; Animals; Colforsin; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Guanosine Triphosphate; Isoproterenol; Male; Norepinephrine; Propranolol; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Forskolin, a tool for rat parotid secretion studies: 45Ca efflux is not related to cAMP.
Topics: Animals; Bucladesine; Calcium; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Isoproterenol; Kinetics; Male; Parotid Gland; Proteins; Rats; Rats, Inbred Strains | 1986 |
A procedure for measuring alpha 2-adrenergic receptor-mediated inhibition of cyclic AMP accumulation in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Brimonidine Tartrate; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mianserin; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide | 1986 |
Additive effect of VIP or isoproterenol on forskolin-stimulated cyclic AMP accumulation in rat prostatic epithelial cells.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; In Vitro Techniques; Isoproterenol; Male; Prostate; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1986 |
Different types of relationship between beta-adrenergic relaxation and activation of cyclic AMP-dependent protein kinase in canine saphenous and portal veins.
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Dogs; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Portal Vein; Protein Kinases; Receptors, Adrenergic, beta; Saphenous Vein | 1986 |
Comparative effects of forskolin and isoproterenol on the cyclic AMP content of human adipocytes.
Topics: Adipose Tissue; Clonidine; Colforsin; Cyclic AMP; Epinephrine; Humans; Isoproterenol | 1987 |
Beta-adrenergic receptors and cyclic adenosine monophosphate generation in human fetal lung.
Topics: Alprostadil; Colforsin; Cyclic AMP; Gestational Age; Humans; Iodocyanopindolol; Isoproterenol; Lung; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1987 |
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sodium Fluoride | 1987 |
Adenosine and oxytocin reverse antagonism of cyclic AMP elevating agents to insulin activation of adipocyte pyruvate dehydrogenase.
Topics: Adenosine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Insulin; Insulin Antagonists; Isoproterenol; Male; Oxytocin; Phenylisopropyladenosine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains | 1987 |
Pertussis toxin attenuates atrial natriuretic factor-mediated inhibition of adenylate cyclase. Involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Male; Molecular Weight; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Ketotifen increases cyclic adenosine 3',5'-monophosphate in intact human lymphocyte and potentiates other adenylate cyclase activating agents.
Topics: Adenylyl Cyclases; Alprostadil; Colforsin; Cyclic AMP; Drug Synergism; Humans; Hydrocortisone; Isoproterenol; Ketotifen; Lymphocytes | 1987 |
Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Vasodilator Agents; Virulence Factors, Bordetella | 1987 |
Hormonal regulation of phospholipid methyltransferase by 3',5'-cyclic adenosine monophosphate-dependent and independent mechanisms.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Epinephrine; Insulin; Isoproterenol; Kinetics; Male; Methyltransferases; Oxytocin; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Protein Kinases; Rats | 1987 |
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Isoproterenol; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sarcolemma; Thionucleotides | 1987 |
The time course of changes in force and cyclic AMP levels produced by isoproterenol and forskolin in isolated rabbit detrusor muscle.
Topics: Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rabbits; Time Factors; Urinary Bladder | 1987 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Forskolin refractoriness. Exposure to the diterpene alters guanine nucleotide-dependent adenylate cyclase and calcium-uptake activity of cells cultured from the rat aorta.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium; Female; Guanine Nucleotides; Isoproterenol; Rats; Rats, Inbred Strains | 1987 |
Short-term hyperthyroidism modulates adenosine receptors and catalytic activity of adenylate cyclase in adipocytes.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Catalysis; Cell Membrane; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Female; Hyperthyroidism; In Vitro Techniques; Isoproterenol; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1987 |
Evidence that the lipolytic defect induced by estradiol-treatment in hamster adipocytes is related to an estrogen receptor-mediated defect in the adenylate cyclase catalytic subunit but not in Ns.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Bucladesine; Cell Membrane; Colforsin; Cricetinae; Estradiol; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Kinetics; Lipolysis; Male; Mesocricetus; Receptors, Estrogen; Theophylline | 1987 |
Catecholamine-induced myocardial potassium uptake mediated by beta 1-adrenoceptors and adenylate cyclase activation in the pig.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glucose; Isoproterenol; Male; Myocardium; Potassium; Receptors, Adrenergic, beta; Stimulation, Chemical; Swine | 1987 |
Unimpaired coupling of phosphorylated, desensitized beta-adrenoceptor to Gs in a reconstitution system.
Topics: Adenylyl Cyclases; Animals; Colforsin; Erythrocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phosphorylation; Receptors, Adrenergic, beta; Thionucleotides; Turkeys | 1987 |
Diet restriction retards the age-related loss of beta-adrenergic receptors and adenylate cyclase activity in rat lung.
Topics: Adenylyl Cyclases; Aging; Animal Nutritional Physiological Phenomena; Animals; Colforsin; Diet; Epinephrine; Isoproterenol; Lung; Male; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1987 |
Similarities in cAMP responses between murine lymphoid cell lines and subsets of mouse lymphocytes.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Enzyme Activation; Histamine; Isoproterenol; Lymphocytes; Mice; Prostaglandins E; Protein Kinases | 1987 |
Alterations in the myocardial beta-adrenoceptor system of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Catecholamines; Colforsin; Diabetes Mellitus, Experimental; Electric Stimulation; Glucagon; Glycated Hemoglobin; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Regulation of protein kinase C by cyclic adenosine 3':5'-monophosphate and a tumor promoter in skeletal myoblasts.
Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Line; Cell Membrane; Cell Transformation, Viral; Colforsin; Cyclic AMP; Cytosol; Isoproterenol; Muscles; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1987 |
Role of cyclic AMP in renin secretion by human transfected juxtaglomerular cells.
Topics: Bucladesine; Cell Transformation, Viral; Cells, Cultured; Cimetidine; Colforsin; Cyclic AMP; Histamine; Humans; Isoproterenol; Juxtaglomerular Apparatus; Renin; Simian virus 40; Transfection | 1986 |
Heterologous regulations of cAMP responses in pregnant rat myometrium. Evolution from a stimulatory to an inhibitory prostaglandin E2 and prostacyclin effect.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Aspirin; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Estradiol; Female; Gestational Age; GTP-Binding Proteins; Isoproterenol; Myometrium; Pertussis Toxin; Pregnancy; Pregnancy, Animal; Prostaglandins E; Rats; Virulence Factors, Bordetella | 1987 |
Forskolin inhibition of hexose transport in cardiomyocytes.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Colforsin; Cyclic AMP; Epinephrine; Hexoses; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Male; Methylglucosides; Myocardium; Rats | 1987 |
Regulation of hormone-stimulated cyclic AMP accumulation in intact human mononuclear leukocytes by blood plasma.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Alprostadil; Cold Temperature; Colforsin; Cyclic AMP; GTP-Binding Proteins; Histamine; Humans; Isoproterenol; Lymphocytes; Monocytes; Virulence Factors, Bordetella | 1986 |
Insulin stimulation of cyclic AMP phosphodiesterase is independent from the G-protein pathways involved in adenylate cyclase regulation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Insulin; Isoproterenol; Male; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1986 |
Adenylate cyclase activity of NIH 3T3 cells morphologically transformed by ras genes.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colforsin; Enzyme Activation; GTP-Binding Proteins; Harvey murine sarcoma virus; Isoproterenol; Mice; Oncogenes | 1986 |
Regulation of rat heart membrane adenylate cyclase by magnesium and manganese.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Male; Manganese; Myocardium; Rats | 1986 |
Evidence for dual modulation of pepsinogen secretion using isoproterenol, carbachol, CCK-8, forskolin, 8 bromo-cAMP, and A23187 probes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcimycin; Calcium; Calmodulin; Carbachol; Colforsin; Enzyme Activation; Gastric Fundus; In Vitro Techniques; Isoproterenol; Pepsinogens; Rabbits; Sincalide; Stimulation, Chemical | 1986 |
Increase of adenylate cyclase catalytic-unit activity by dexamethasone in rat osteoblast-like cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cations, Divalent; Cell Line; Colforsin; Dexamethasone; Enzyme Activation; Ethers; GTP-Binding Proteins; Ionomycin; Isoproterenol; Osteoblasts; Parathyroid Hormone; Rats | 1986 |
Stimulatory and inhibitory regulation of myocardial adenylate cyclase by 5'-guanylyl-imidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Myocardium; Rats | 1987 |
The influence of EDTA on adenylate cyclase activity in membranes from rat and mouse myocardium.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Edetic Acid; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Kinetics; Mice; Myocardium; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
Halothane attenuation of muscarinic inhibition of adenylate cyclase in rat heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Colforsin; GTP-Binding Proteins; Halothane; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Action of forskolin on non-electrolyte permeability across the urinary bladder of Bufo bufo as compared to that of various hormones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bufo bufo; Cell Membrane Permeability; Colforsin; Erythritol; Hormones; Isoproterenol; Urea; Urinary Bladder | 1988 |
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells.
Topics: Amnion; Calcium; Cells, Cultured; Colforsin; Dinoprostone; Egtazic Acid; Epithelium; Humans; Inositol Phosphates; Isoproterenol; Oxytocin; Prostaglandins E; Protein Kinase C; Reference Values; Ritodrine; Sugar Phosphates; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
The alpha 1-adrenergic transduction system in hamster brown adipocytes. Release of arachidonic acid accompanies activation of phospholipase C.
Topics: Adipose Tissue, Brown; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Colforsin; Cricetinae; Cyclohexanones; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Inositol Phosphates; Insulin; Isoproterenol; Lipid Metabolism; Male; Phenylephrine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Manganous chloride stimulation of adenylate cyclase responsiveness in ocular ciliary process membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chlorides; Ciliary Body; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Manganese; Manganese Compounds; Rabbits; Sodium Fluoride; Vasoactive Intestinal Peptide | 1988 |
Forskolin binding to intact S49 lymphoma cells.
Topics: Animals; Binding, Competitive; Colforsin; Cytochalasin B; Epinephrine; Isoproterenol; Ligands; Lymphoma; Propranolol; Radioimmunoassay; Stereoisomerism; Tumor Cells, Cultured | 1988 |
Effects of acetylcholine, isoprenaline and forskolin on electrolyte and protein composition of rabbit mandibular saliva.
Topics: Acetylcholine; Animals; Chlorides; Colforsin; Electrolytes; In Vitro Techniques; Isoproterenol; Male; Potassium; Rabbits; Saliva; Salivary Proteins and Peptides; Secretory Rate; Sodium; Submandibular Gland | 1988 |
Human eccrine sweat gland epithelial cultures express ductal characteristics.
Topics: Amiloride; Bradykinin; Carbachol; Cells, Cultured; Colforsin; Epithelium; Humans; Isoproterenol; Membrane Potentials; Piroxicam; Sodium; Sweat Glands | 1988 |
Effects of adrenaline, isoprenaline and forskolin on pregnant human myometrial preparations.
Topics: Adenylyl Cyclases; Colforsin; Epinephrine; Female; Humans; Isoproterenol; Myometrium; Pregnancy; Uterine Contraction | 1988 |
The effects of isoproterenol on intracellular calcium concentration.
Topics: Animals; Atropine; Calcium; Carbachol; Cattle; Colforsin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Phorbol Esters; Propranolol; Trachea; Vasoactive Intestinal Peptide | 1988 |
Inotropic responses change during postnatal maturation in rabbit.
Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Colforsin; Female; Heart; Imidazoles; Isoproterenol; Male; Milrinone; Myocardial Contraction; Pyridones; Rabbits; Reference Values; Software | 1988 |
Reduction of rat pineal N-acetyltransferase activity by fetal alcohol exposure.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Colforsin; Ethanol; Female; Fetus; Isoproterenol; Pineal Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1987 |
NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells.
Topics: Adenylyl Cyclases; Animals; Biological Transport; Cell Line; Colforsin; Dinoprostone; Dogs; Epinephrine; Epithelium; Furosemide; Isoproterenol; Kidney; Kinetics; Ouabain; Prostaglandins; Prostaglandins E; Sodium Chloride | 1986 |
Gold(III) inhibits activated human osteosarcoma adenylate cyclase by an action at or near the catalytic component.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cell Line; Cell Membrane; Colforsin; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Gold; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Osteosarcoma; Prostaglandins E | 1987 |
Interactions of insulin, catecholamines and adenosine in the regulation of glucose transport in isolated rat cardiac myocytes.
Topics: 3-O-Methylglucose; Adenosine; Adenosine Deaminase; Animals; Biological Transport, Active; Catecholamines; Colforsin; Female; Glucose; Heart; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Methylglucosides; Methylglycosides; Myocardium; Phenylisopropyladenosine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Neuropeptide Y inhibits renin release by a pertussis toxin-sensitive mechanism.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Colforsin; Guanfacine; Guanidines; Hydronephrosis; Imidazoles; Isoproterenol; Kidney; Male; Neuropeptide Y; Norepinephrine; Perfusion; Pertussis Toxin; Phenylacetates; Rats; Rats, Inbred Strains; Renin; Vascular Resistance; Virulence Factors, Bordetella | 1987 |
Characteristics of adaptive supersensitivity in the left atrium of the guinea pig.
Topics: Albuterol; Animals; Colforsin; Guanylyl Imidodiphosphate; Guinea Pigs; Heart Atria; Isoproterenol; Male; Metanephrine; Myocardial Contraction; Norepinephrine; Reserpine | 1987 |
Parathyroid hormone-induced lipolysis in human adipose tissue.
Topics: Adipose Tissue; Adult; Aged; Colforsin; Female; Humans; Isoproterenol; Lipolysis; Male; Middle Aged; Parathyroid Hormone; Peptide Fragments; Teriparatide | 1987 |
Adenylate cyclase stimulation by VIP in rat and human parotid membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Isoproterenol; Male; Parotid Gland; Rats; Rats, Inbred Strains; Species Specificity; Vasoactive Intestinal Peptide | 1987 |
Cholinergic attenuation of the electrophysiological effects of forskolin.
Topics: Acetylcholine; Action Potentials; Animals; Chick Embryo; Colforsin; Electric Stimulation; Female; Guinea Pigs; Isoproterenol; Kinetics; Male; Microelectrodes; Myocardium; Parasympathetic Nervous System | 1986 |
Effect of chronic administration of doxorubicin on cardiac adenylate cyclase activity in mice.
Topics: Adenylyl Cyclases; Animals; Colforsin; Doxorubicin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Mice; Myocardium; Organ Size; Sodium Fluoride | 1986 |
Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cell Membrane Permeability; Colforsin; Digitonin; Guanosine Triphosphate; Isoproterenol; Kinetics; Rats | 1986 |
Forskolin activation of adenylate cyclase in mouse parotid membranes.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Mice; Parotid Gland; Thionucleotides | 1986 |
The effect of forskolin on the isometric contraction of the isolated hemidiaphragm of the rat.
Topics: Aminophylline; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Female; Isometric Contraction; Isoproterenol; Male; Muscle Contraction; Rats | 1986 |
Apparent chloride conductance of subconfluent Madin Darby canine kidney cells.
Topics: Animals; Anthracenes; Cell Line; Chlorides; Colforsin; Dogs; Furosemide; Isoproterenol; Kidney; Membrane Potentials; Microelectrodes; ortho-Aminobenzoates | 1986 |
Alterations of rat cardiac adenylate cyclase activity with age.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Secretin; Sodium Fluoride | 1986 |
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Propranolol; Sodium Fluoride; Ureter | 1986 |
The hysteretic effect of Gpp(NH)p on adenylate cyclase is not altered by Mg2+ in adipocyte membranes of ob/ob mice.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cholera Toxin; Colforsin; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Male; Mice; Mice, Obese; Pertussis Vaccine; Regression Analysis; Sodium Fluoride | 1986 |
Heterologous desensitization of the inhibitory A1 adenosine receptor-adenylate cyclase system in rat adipocytes. Regulation of both Ns and Ni.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Colforsin; Isoproterenol; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Fluoride | 1987 |
cAMP-dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady-state relationship with lipolytic and antilipolytic modulators.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Colforsin; Cosyntropin; Deoxyadenosines; Dideoxyadenosine; Enzyme Activation; Glucagon; Glycerol; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
Absence of the inhibitory effect of guanine nucleotides on adenylate cyclase activity in white adipocyte membranes of the ob/ob mouse. Effect of the ob gene.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Bacterial Toxins; Cholera Toxin; Colforsin; Diterpenes; GTP-Binding Proteins; Guanine Nucleotides; Isoproterenol; Magnesium; Male; Mice; Mice, Obese; Pertussis Toxin; Virulence Factors, Bordetella | 1985 |
Ninhibin: a sperm factor attenuates the atrial natriuretic factor mediated inhibition of adenylate cyclase: possible involvement of inhibitory guanine nucleotide regulatory protein.
Topics: Acrosin; Adenylyl Cyclase Inhibitors; Animals; Aorta; Cattle; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Endopeptidases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Natriuretic Agents; Proteins; Rats; Thionucleotides | 1985 |
Effect of gonadotrophins on progesterone secretion by cultured granulosa cells obtained from human preovulatory follicles.
Topics: Cell Count; Cell Separation; Cells, Cultured; Chorionic Gonadotropin; Clomiphene; Colforsin; Female; Fertilization in Vitro; Granulosa Cells; Humans; Isoproterenol; Menotropins; Progesterone | 1985 |
Characterization of the adenylate cyclase of the rat corpus luteum during luteolysis induced by a prostaglandin F2 alpha analogue.
Topics: Adenylyl Cyclases; Animals; Cloprostenol; Colforsin; Corpus Luteum; Drug Synergism; Enzyme Activation; Female; Guanosine Triphosphate; Isoproterenol; Luteolytic Agents; Magnesium; Prostaglandins F, Synthetic; Rats; Rats, Inbred Strains; RNA Cap Analogs | 1986 |
Forskolin induction of S-100 protein in glioma and hybrid cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Cycloheximide; Dactinomycin; Diterpenes; Glioma; Hybrid Cells; Isoproterenol; Kinetics; Mice; Neuroblastoma; Prostaglandins E; Rats; S100 Proteins; Theophylline | 1985 |
Stimulation of lipolysis in rat heart myocytes by isoproterenol.
Topics: Animals; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Epinephrine; Glycerol; Isoproterenol; Lipolysis; Male; Methoxamine; Myocardium; Rats; Rats, Inbred Strains; Stimulation, Chemical; Triglycerides | 1985 |
Comparison of the effects of forskolin and isoprenaline on tracheal, cardiac and skeletal muscles from guinea-pig.
Topics: Animals; Cardiotonic Agents; Colforsin; Diterpenes; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Muscles; Myocardial Contraction; Papillary Muscles; Practolol; Prenalterol; Trachea | 1985 |
Relationship among calmodulin-, forskolin-, and guanine nucleotide-dependent adenylate cyclase activities in cerebellar membranes: studies by limited proteolysis.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Cattle; Cerebellum; Chymotrypsin; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Guanine Nucleotides; Guanylyl Imidodiphosphate; Isoproterenol; Membranes; Nickel | 1985 |
Adenylate cyclase activity and motor behavior following cerebral ischemia in the unanesthetized gerbil.
Topics: Adenylyl Cyclases; Animals; Carotid Arteries; Cerebral Cortex; Colforsin; Diterpenes; Gerbillinae; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Ischemic Attack, Transient; Isoproterenol; Ligation; Male; Motor Activity; Time Factors | 1985 |
Phorbol myristate acetate causes in guinea-pig lung parenchymal strip a maintained spasm which is relatively resistant to isoprenaline.
Topics: Aminophylline; Animals; Colforsin; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Forskolin inhibition of glucose metabolism in rat adipocytes independent of adenosine 3',5'-monophosphate accumulation and lipolysis.
Topics: Adipose Tissue; Animals; Carbon Dioxide; Colforsin; Cyclic AMP; Diterpenes; Female; Glucose; Isoproterenol; Lipolysis; Male; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains | 1984 |
The effect of dexamethasone on parathyroid hormone stimulation of adenylate cyclase in ROS 17/2.8 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Corticosterone; Cyclic AMP; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hydrocortisone; Isoproterenol; Mice; Osteosarcoma; Parathyroid Hormone; Time Factors | 1984 |
Characterization of the homologous and heterologous desensitization of rat Leydig-tumour-cell adenylate cyclase.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Centrifugation, Density Gradient; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; In Vitro Techniques; Isoproterenol; Kinetics; Leydig Cell Tumor; Luteinizing Hormone; Prostaglandins E; Rats | 1984 |
Hormonal activation of the cAMP-dependent protein kinases in AtT20 cells. Preferential activation of protein kinase I by corticotropin releasing factor, isoproterenol, and forskolin.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Diterpenes; Enzyme Activation; Isoproterenol; Kinetics; Mice; Pituitary Neoplasms; Protein Kinases | 1984 |
Cyclic AMP mediates beta-adrenergic-induced increases in N-linked protein glycosylation in rat parotid acinar cells.
Topics: Animals; Chromatography, Gel; Colforsin; Cyclic AMP; Diterpenes; Dolichol Phosphates; Electrophoresis, Polyacrylamide Gel; Glycoproteins; In Vitro Techniques; Isoproterenol; Male; Mannose; Nucleotides, Cyclic; Oligosaccharides; Parotid Gland; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides | 1984 |
1,25 Dihydroxyvitamin D causes attenuation of cyclic AMP responses in monocyte-like cells.
Topics: Calcitriol; Cardiotonic Agents; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Humans; Hydroxycholecalciferols; Isoproterenol; Kinetics; Monocytes | 1984 |
Phosphate uptake by kidney epithelial (LLC-PK1) cells.
Topics: Adenylyl Cyclases; Animals; Biological Transport, Active; Bucladesine; Cell Line; Colforsin; Diterpenes; Epithelium; Isoproterenol; Kidney; Kinetics; Male; Parathyroid Hormone; Phosphates; Sodium; Swine; Vasopressins | 1984 |
Adenosine 3',5'-monophosphate (cAMP)-dependent protein kinase activity in rodent pituitary tissue: possible role in cAMP-dependent hormone secretion.
Topics: Adrenocorticotropic Hormone; Animals; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Mice; Phosphorylation; Pituitary Gland; Pituitary Neoplasms; Propranolol; Protein Kinases | 1984 |
Thyroid-catecholamine interactions in isolated rat brown adipocytes.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Caprylates; Catecholamines; Colforsin; Cyclic AMP; Diterpenes; Fatty Acids, Nonesterified; Female; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Isoproterenol; Lipolysis; Organ Size; Oxygen Consumption; Phenylephrine; Protein Binding; Rats; Thyroid Hormones | 1984 |
A low dose of forskolin increases cyclic AMP levels and cyclic AMP dependent protein kinase activity in bovine coronary arteries without causing relaxation.
Topics: Animals; Cattle; Colforsin; Coronary Vessels; Cyclic AMP; Diterpenes; In Vitro Techniques; Isoproterenol; Muscle, Smooth, Vascular; Protein Kinases; Radioimmunoassay; Vasodilation | 1984 |
Is renin secretion governed by the calcium permeability of the juxtaglomerular cell membrane?
Topics: Angiotensin II; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Juxtaglomerular Apparatus; Kinetics; Rats; Renin; Trifluoperazine; Verapamil | 1984 |
Effects of isoproterenol and forskolin on tension, cyclic AMP levels, and cyclic AMP dependent protein kinase activity in bovine coronary artery.
Topics: Animals; Cardiotonic Agents; Cattle; Colforsin; Coronary Vessels; Cyclic AMP; Diterpenes; In Vitro Techniques; Isoproterenol; Muscle Contraction; Protein Kinases | 1984 |
Adrenergic responsiveness in experimental uremia.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dihydroalprenolol; Diterpenes; Isoproterenol; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Uremia | 1984 |
Effects of forskolin and isoproterenol on cyclic AMP and tension in the myometrium.
Topics: Acetylcholine; Animals; Colforsin; Cyclic AMP; Diterpenes; Drug Interactions; Female; Injections, Intramuscular; Isoproterenol; Myometrium; Pregnancy; Rabbits; Rats; Uterine Contraction | 1984 |
Activation of cyclic AMP-generating systems in brain membranes and slices by the diterpene forskolin: augmentation of receptor-mediated responses.
Topics: Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Male; Neurotransmitter Agents; Norepinephrine; Rats; Vasoactive Intestinal Peptide | 1982 |
Alpha-2 adrenergic activation inhibits forskolin-stimulated adenylate cyclase activity and lipolysis in human adipocytes.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Antihypertensive Agents; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Lipolysis; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Somatostatin inhibits multireceptor stimulation of cyclic AMP formation and corticotropin secretion in mouse pituitary tumor cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Diterpenes; Isoproterenol; Melitten; Mice; Pituitary Gland; Receptors, Cell Surface; Secretory Rate; Somatostatin; Vasoactive Intestinal Peptide | 1982 |
Pertussis toxin blocks somatostatin's inhibition of stimulated cyclic AMP accumulation in anterior pituitary tumor cells.
Topics: Adenylate Cyclase Toxin; Animals; Antihypertensive Agents; Bacterial Toxins; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Kinetics; Mice; Pertussis Toxin; Pituitary Gland, Anterior; Pituitary Neoplasms; Radioimmunoassay; Somatostatin; Virulence Factors, Bordetella | 1983 |
Effects of forskolin in rat vas deferens--evidence for facilitatory beta-adrenoceptors.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Diterpenes; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Forskolin: effects on mouse parotid gland function.
Topics: Amylases; Animals; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Mice; Parotid Gland; Protein Kinases | 1983 |
Prostacyclin biosynthesis in vascular endothelium is not inhibited by cyclic AMP. Studies with 3-isobutyl-1-methylxanthine and forskolin.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Epoprostenol; Humans; Isoproterenol; Prostaglandin Antagonists; Prostaglandins; Stimulation, Chemical; Theophylline; Umbilical Veins | 1982 |
Selective reduction of forskolin-stimulated cyclic AMP accumulation by inhibitors of protein synthesis.
Topics: Animals; Astrocytoma; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dichlororibofuranosylbenzimidazole; Diterpenes; Emetine; Isoproterenol; Protein Biosynthesis; Rats; RNA | 1983 |
The regulation of glucose transport by cAMP stimulators via three different mechanisms in rat and human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-O-Methylglucose; Adipose Tissue; Animals; Bucladesine; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Glucose; Humans; Insulin; Isoproterenol; Kinetics; Male; Methylglucosides; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Theophylline | 1983 |
Stimulation of cAMP accumulation and lipolysis in hamster adipocytes with forskolin.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Antihypertensive Agents; Colforsin; Cricetinae; Cyclic AMP; Diterpenes; Isoproterenol; Kinetics; Lipolysis; Mesocricetus; Phenylisopropyladenosine | 1984 |
Forskolin-stimulated cyclic AMP accumulation mediates protein synthesis-dependent refractoriness in C6-2B rat glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Diterpenes; Glioma; Isoproterenol; Neoplasm Proteins; Protein Biosynthesis; Rats | 1983 |
Modulation of renal ATPase activities by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphatases; Animals; Bucladesine; Ca(2+) Mg(2+)-ATPase; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Kidney; Kidney Cortex; Kidney Medulla; Kinetics; Male; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Manganese; Mice; Neoplasms, Experimental; Receptors, Cell Surface; Sodium Fluoride | 1981 |
Forskolin stimulation of thyroid adenylate cyclase and cyclic 3',5'-adenosine monophosphate accumulation.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Diterpenes; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Magnesium; Manganese; Thyroid Gland; Thyrotropin; Time Factors | 1982 |
Stimulation of forskolin of intact S49 lymphoma cells involves the nucleotide regulatory protein of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Guanine Nucleotides; Isoproterenol; Kinetics; Lymphoma | 1982 |
Evidence that forskolin activates turkey erythrocyte adenylate cyclase through a noncatalytic site.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Catalysis; Colforsin; Diterpenes; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanosine Monophosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred Strains; Turkeys | 1983 |
Forskolin as a tool to study the beta-adrenergic receptor-elicited, labeled protein secretion in rat lacrimal gland.
Topics: Animals; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Lacrimal Apparatus; Male; Papaverine; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Decreased beta-adrenergic agonist affinity and adenylate cyclase activity in senescent rat lung.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Colforsin; Dihydroalprenolol; Diterpenes; Female; Guanylyl Imidodiphosphate; Isoproterenol; Lung; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Temperature | 1983 |
Desensitization of beta 2-adrenergic receptors and adrenocorticotropin release.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line; Colforsin; Cyclic AMP; Dihydroalprenolol; Diterpenes; Isoproterenol; Mice; Pituitary Gland, Anterior; Pituitary Neoplasms; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Adenylate cyclase sensitivity to catecholamines and forskolin in rat pia-arachnoid and cerebral microvessels.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Arachnoid; Brain; Catecholamines; Colforsin; Diterpenes; Isoproterenol; Kinetics; Male; Microcirculation; Pia Mater; Rats; Reserpine; Sympatholytics | 1983 |
Effects of selected bronchodilators on antigen- and A23187-induced contraction of guinea-pig trachea.
Topics: Aminophylline; Animals; Anti-Bacterial Agents; Antigens; Bronchodilator Agents; Bucladesine; Calcimycin; Colforsin; Dinoprostone; Diterpenes; Guinea Pigs; Indomethacin; Isoproterenol; Male; Muscle Contraction; Ovalbumin; Prostaglandins E; Trachea | 1983 |
Forskolin: a new biochemical tool for studying gastric secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Antihypertensive Agents; Bufo marinus; Cimetidine; Colforsin; Cyclic AMP; Diterpenes; Gastric Juice; Gastric Mucosa; Histamine; Isoproterenol; Kinetics; Oxygen Consumption; Rabbits; Sodium Fluoride | 1983 |
Comparison of the effects of forskolin and isoproterenol on cyclic AMP levels and tension in bovine coronary artery.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1983 |
Effect of forskolin on primary cultures of astrocytes and oligodendrocytes.
Topics: Alprostadil; Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Neuroglia; Oligodendroglia; Phenylephrine; Prostaglandins E; Rats; Stimulation, Chemical | 1983 |
Forskolin stimulates adenylate cyclase activity, adenosine 3',5'-monophosphate production and peptide release from the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Apomorphine; Colforsin; Cyclic AMP; Diterpenes; Guanosine Triphosphate; Isoproterenol; Kinetics; Melanocyte-Stimulating Hormones; Pituitary Gland; Rats | 1984 |
Distinct mechanisms of forskolin-stimulated cyclic AMP accumulation and forskolin-potentiated hormone responses in C6-2B cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Isoproterenol; Kinetics; Prostaglandins E; Rats; Receptors, Adrenergic, beta | 1984 |
Serum-stimulated cyclic-AMP production in S49 lymphoma cells grown in serum-free medium.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antihypertensive Agents; Blood; Cell Line; Colforsin; Culture Media; Cyclic AMP; Diterpenes; Horses; Isoproterenol; Kinetics; Lymphoma; Mice | 1984 |
Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitroprusside; Papillary Muscles; Rabbits | 1984 |
The effect of prostaglandin synthesis inhibition on the direct stimulation of renin release from rabbit renal cortical slices.
Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Diterpenes; Indomethacin; Isoproterenol; Kidney Cortex; Male; Prostaglandins; Prostaglandins H; Rabbits; Renin | 1984 |
Activation of lipolysis and cyclic AMP accumulation in rabbit adipocytes by isoproterenol in the presence of forskolin or pertussis toxin.
Topics: Adenosine Deaminase; Adenylate Cyclase Toxin; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bacterial Toxins; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Female; Glycerol; Guanine Nucleotides; In Vitro Techniques; Isoproterenol; Lipolysis; Pertussis Toxin; Rabbits; Theophylline; Virulence Factors, Bordetella | 1984 |
Mechanism of heterologous desensitization of the adenylate cyclase system by glucagon in primary cultures of adult rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Glucagon; Guanylyl Imidodiphosphate; Iodocyanopindolol; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sodium Fluoride | 1984 |
Inhibition of antigen and calcium ionophore A23187 induced contractions of guinea pig airways by isoprenaline and forskolin.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Cardiotonic Agents; Colforsin; Diterpenes; Guinea Pigs; Immunization; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Ovalbumin; Trachea | 1983 |
Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation.
Topics: Adenylyl Cyclases; Animals; Bronchodilator Agents; Colforsin; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Lung; Male; Muscle Relaxation; Ovalbumin; Prostaglandins E; Trachea; Vasoactive Intestinal Peptide | 1984 |
Forskolin lowers intraocular pressure by reducing aqueous inflow.
Topics: Adenylyl Cyclases; Animals; Aqueous Humor; Blood Pressure; Ciliary Body; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Female; Humans; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Macaca; Male; Rabbits; Regional Blood Flow; Timolol | 1984 |
Leucine-enkephalin modulation of catecholamine positive chronotropy in rat atria is receptor-specific and calcium-dependent.
Topics: Animals; Calcium; Catecholamines; Colforsin; Diterpenes; Enkephalin, Leucine; Heart; Heart Rate; Isoproterenol; Male; Naloxone; Norepinephrine; Rats; Receptors, Adrenergic | 1984 |
Bronchodilating activity of forskolin in vitro and in vivo.
Topics: Acetylcholine; Anaphylaxis; Animals; Bronchodilator Agents; Chlorpheniramine; Colforsin; Diterpenes; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Muscle, Smooth; SRS-A; Trachea | 1984 |
Secretin-induced changes in rate, contractility and adenylate cyclase activity in rat heart atria.
Topics: Adenylyl Cyclases; Animals; Atrial Function; Cardiotonic Agents; Colforsin; Diterpenes; Heart Atria; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Secretin; Stimulation, Chemical | 1984 |
Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Rats; Rats, Inbred Strains | 1983 |
Effects of forskolin on androgen production by mouse interstitial cells in vitro. Interactions with luteinizing hormone and isoproterenol.
Topics: Androgens; Animals; Antihypertensive Agents; Cardiotonic Agents; Cells, Cultured; Colforsin; Connective Tissue; Diterpenes; Drug Interactions; Isoproterenol; Luteinizing Hormone; Male; Mice; Mice, Inbred Strains; Testis | 1983 |
Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Bacterial Toxins; Colforsin; Diterpenes; Enzyme Activation; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Pertussis Toxin; Rabbits; Rats; Rats, Inbred Strains; Time Factors; Virulence Factors, Bordetella | 1983 |
Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosphate; Humans; Isoproterenol; Lymphocytes; Male; Sodium Fluoride | 1982 |
Isoprenaline and forskolin increase evoked vasopressin release from rat pituitary.
Topics: Animals; Colforsin; Diterpenes; Electric Stimulation; Female; Isoproterenol; Pituitary Gland; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Stimulation, Chemical; Vasopressins | 1982 |
The positive inotropic-acting forskolin, a potent adenylate cyclase activator.
Topics: Adenylyl Cyclases; Animals; Cardiotonic Agents; Colforsin; Diterpenes; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Isoproterenol; Membranes; Myocardium; Protein Kinases; Rabbits; Rats; Rats, Inbred Strains | 1981 |
beta-adrenergic and cholinergic modulation of the inwardly rectifying K+ current in guinea-pig ventricular myocytes.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardium; Parasympathetic Nervous System; Potassium Channels; Receptors, Adrenergic, beta | 1995 |
Beta-adrenergic and cholinergic modulation of inward rectifier K+ channel function and phosphorylation in guinea-pig ventricle.
Topics: Acetylcholine; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Ethers, Cyclic; Ganglia, Parasympathetic; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Okadaic Acid; Patch-Clamp Techniques; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Potassium Channels; Receptors, Adrenergic, beta; Sympathomimetics; Virulence Factors, Bordetella | 1995 |
Age-dependent changes in response of rat prostatic tissues to isoproterenol and forskolin: changes with sexual maturation in function of G proteins.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Cell Nucleus; Colforsin; GTP-Binding Proteins; Isoproterenol; Male; Prostate; Rats; Rats, Wistar; Sexual Maturation; Signal Transduction; Testosterone | 1995 |
Protein kinase C regulation of the adenylyl cyclase system in rat prostatic epithelium.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Guanylyl Imidodiphosphate; Isoproterenol; Male; Neuropeptides; Neurotransmitter Agents; Pertussis Toxin; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Prostate; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1995 |
Adenylyl cyclase activity in human decidua and myometrium during pregnancy and labour.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Colforsin; Decidua; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Labor, Obstetric; Middle Aged; Myometrium; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Sodium Fluoride; Stimulation, Chemical; Uterus | 1995 |
cAMP generation inhibits inositol 1,4,5-trisphosphate binding in rabbit tracheal smooth muscle.
Topics: Animals; Colforsin; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Isoproterenol; Muscle, Smooth; Osmolar Concentration; Rabbits; Trachea | 1995 |
Diazepam potentiates the positive inotropic effect of isoprenaline in rat ventricle strips: role of cyclic AMP.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bucladesine; Cardiotonic Agents; Colforsin; Cyclic AMP; Diazepam; Drug Synergism; Electric Stimulation; Female; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Sprague-Dawley | 1995 |
Forskolin-stimulated adenylyl cyclase activity is decreased but beta 2-adrenoceptor function is unchanged in primary hypertension.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Binding, Competitive; Cell Membrane; Colforsin; Female; Hemodynamics; Humans; Hypertension; Isoproterenol; Leukocytes, Mononuclear; Male; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Sex Factors | 1993 |
Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Binding, Competitive; Carbachol; Cardiomegaly; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Indapamide; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Signal Transduction | 1993 |
Cyclic AMP regulation of messenger RNA level of the stimulatory GTP-binding protein Gs alpha. Isoproterenol, forskolin and 8-bromoadenosine 3':5'-cyclic monophosphate increase the level of Gs alpha mRNA in cultured astroglial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Astrocytes; Base Sequence; Blotting, Northern; Brain; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; GTP-Binding Proteins; Isoproterenol; Kinetics; Macromolecular Substances; Molecular Sequence Data; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Subcellular Fractions; Time Factors | 1994 |
Phorbol ester has different effects on forskolin and beta-adrenergic-stimulated cAMP accumulation in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cytosol; In Vitro Techniques; Isoproterenol; Male; Membranes; Mice; Parotid Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Endothelin subtype B receptors are coupled to adenylate cyclase via inhibitory G protein in cultured bovine endothelial cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelium, Vascular; Glycopeptides; GTP-Binding Proteins; Isoproterenol; Nitric Oxide; Receptors, Endothelin | 1993 |
Pasteurella haemolytica leukotoxin induces histamine release from bovine pulmonary mast cells.
Topics: Animals; Bacterial Toxins; Calcimycin; Cattle; Cells, Cultured; Colforsin; Exotoxins; Histamine Release; Hydrocortisone; Isoproterenol; Lung; Mannheimia haemolytica; Mast Cells; Propranolol; Verapamil | 1994 |
Endothelin ETA-receptors couple to inositol phosphate formation and inhibition of adenylate cyclase in human right atrium.
Topics: Adenylyl Cyclase Inhibitors; Adult; Aged; Colforsin; Cyclic AMP; Endothelins; Enzyme Activation; Female; Heart Atria; Humans; In Vitro Techniques; Inositol Phosphates; Isoproterenol; Male; Membranes; Middle Aged; Myocardium; Protein Kinase C; Receptors, Endothelin; Signal Transduction | 1994 |
Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Ethanolamines; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Ryanodine; Swine; Thromboxane A2; Vasodilator Agents | 1994 |
Cross talk among cyclic AMP, cyclic GMP, and Ca(2+)-dependent intracellular signalling mechanisms in brain capillary endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Intracellular Membranes; Isoproterenol; Rats; Receptors, Endothelin; Signal Transduction | 1994 |
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion.
Topics: Bradykinin; Bumetanide; Calcimycin; Cell Line; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Cytoplasmic Granules; Desmosomes; Epithelium; Histamine; Humans; Intercellular Junctions; Isoproterenol; Kinetics; Lung Neoplasms; Membrane Proteins; Methacholine Chloride; Microscopy, Electron; Nystatin; Ouabain; Sodium; Trypsin; Tumor Cells, Cultured | 1994 |
CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance.
Topics: Adenosine Triphosphate; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Isoproterenol; Kinetics; Lung Neoplasms; Membrane Potentials; Membrane Proteins; Nitrobenzoates; Time Factors; Trypsin; Tumor Cells, Cultured | 1994 |
Effect of interventions that increase cyclic AMP levels on susceptibility to ventricular fibrillation in unanesthetized dogs.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Anesthesia; Animals; Colforsin; Cyclic AMP; Death, Sudden, Cardiac; Dogs; Enzyme Activation; Isoproterenol; Myocardial Infarction; Myocardium; Ventricular Fibrillation | 1994 |
Limited modulation of the mitogen-activated protein kinase pathway by cyclic AMP in rat parotid acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Isoproterenol; Kinetics; Myelin Basic Protein; Parotid Gland; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats | 1994 |
A novel Gs alpha mutant in a patient with Albright hereditary osteodystrophy uncouples cell surface receptors from adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aluminum; Base Sequence; Child, Preschool; Codon; Colforsin; Cyclic AMP; Erythrocyte Membrane; Exons; Fluorine; Genes, Dominant; GTP-Binding Proteins; Heterozygote; Humans; Isoproterenol; Male; Molecular Sequence Data; Mutation; Phenotype; Pseudohypoparathyroidism; Receptors, Cell Surface; Recombinant Proteins; Signal Transduction | 1994 |
Rate-limiting steps in activation of cardiac Cl- current revealed by photolytic application of cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Ethers, Cyclic; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Kinetics; Membrane Potentials; Okadaic Acid; Photolysis; Temperature; Time Factors; Ultraviolet Rays; Vasoconstrictor Agents | 1994 |
Influence of atrial natriuretic peptide on cyclic nucleotides and amylase release in rat parotid salivary gland in vitro.
Topics: Amylases; Animals; Atrial Natriuretic Factor; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Isoproterenol; Male; Nitroprusside; Parotid Gland; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
Angiotensin II induced alteration of cyclic adenosine 3',5'-monophosphate generation in the hypertrophic myocardium of Dahl salt-sensitive rat on a high-salt diet.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Angiotensin II; Animals; Cardiomegaly; Cell Size; Colforsin; Cyclic AMP; Diet; Flow Cytometry; In Vitro Techniques; Isoproterenol; Male; Muscle Proteins; Pertussis Toxin; Rats; Rats, Inbred Strains; Sodium Chloride; Virulence Factors, Bordetella | 1994 |
IL-1 inhibits beta-adrenergic control of cardiac calcium current: role of L-arginine/nitric oxide pathway.
Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Animals; Arginine; Calcium Channels; Cells, Cultured; Colforsin; Guinea Pigs; Heart; Heart Ventricles; Humans; Interleukin-1; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, beta; Recombinant Proteins | 1994 |
CGRP enhances induction of NO synthase in vascular smooth muscle cells via a cAMP-dependent mechanism.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Cells, Cultured; Citrulline; Colforsin; Cyclic AMP; Interleukin-1; Isoproterenol; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Platelet Aggregation; Protein Kinases; Rats; Rats, Wistar; RNA, Messenger; Thionucleotides | 1994 |
Effects of mutations in cAMP-dependent protein kinase on chloride efflux in Caco-2 human colonic carcinoma cells.
Topics: Carbachol; Chloride Channels; Colforsin; Colonic Neoplasms; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Enzyme Activation; Humans; Isoproterenol; Membrane Proteins; Mutation; Second Messenger Systems; Transformation, Genetic; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Zinc | 1995 |
Isoproterenol causes hyperpolarization through opening of ATP-sensitive potassium channels in vascular smooth muscle of the canine saphenous vein.
Topics: Animals; Atenolol; Charybdotoxin; Colforsin; Dogs; Female; Glyburide; Ion Channel Gating; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Potassium Channels; Propanolamines; Receptors, Adrenergic, beta; Saphenous Vein; Scorpion Venoms; Yohimbine | 1995 |
cAMP is not involved in interleukin-1-induced interleukin-6 release from human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Astrocytoma; Bucladesine; Colforsin; Cyclic AMP; Humans; Interleukin-1; Interleukin-6; Isoproterenol; Tumor Cells, Cultured | 1994 |
Effect of PT-treatment on ANP-mediated inhibition of adenylate cyclase and amylase release in rat parotid gland.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amylases; Animals; Atrial Natriuretic Factor; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Parotid Gland; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Virulence Factors, Bordetella | 1994 |
Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion.
Topics: Asthma; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Humans; Intercellular Adhesion Molecule-1; Isoproterenol; Lymphocyte Activation; Muscle, Smooth; T-Lymphocytes; Trachea; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1995 |
Isoproterenol exerts cyclic AMP independent effects on DNA synthesis in cultured adventitial fibroblasts from spontaneously hypertensive and Wistar-Kyoto rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Epidermal Growth Factor; Fibroblasts; Isoproterenol; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Role of nitric oxide and cAMP in beta-adrenoceptor-induced pial artery vasodilation.
Topics: Albuterol; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Dobutamine; Enzyme Activation; Female; Isoproterenol; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Pia Mater; Receptors, Adrenergic, beta; Swine; Vasodilation | 1995 |
Role of F-actin in the activation of Na(+)-K(+)-Cl- cotransport by forskolin and vasopressin in mouse kidney cultured thick ascending limb cells.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Animals; Arginine Vasopressin; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cytoskeleton; Dinoprostone; Diuretics; Ion Transport; Isoproterenol; Loop of Henle; Male; Mice; Nocodazole; Ouabain; Parathyroid Hormone; Phalloidine; Potassium; Sodium | 1994 |
A comparison of the effects of isoproterenol and forskolin on immunologic and nonimmunologic release of histamine from guinea-pig superfused trachea and dispersed tracheal cells.
Topics: Animals; Colforsin; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Mast Cells; Ovalbumin; p-Methoxy-N-methylphenethylamine; Trachea; Tubocurarine | 1995 |
Autonomic regulation of cardiac chloride current.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Autonomic Agents; Chloride Channels; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Isoproterenol | 1994 |
Developmental changes in modulation of contractility of rabbit hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Blood Pressure; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Heart Ventricles; Isoproterenol; Myocardial Contraction; Phosphodiesterase Inhibitors; Rabbits; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Function, Left | 1995 |
Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Binding, Competitive; Cell Line; Cell Membrane; Colforsin; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Humans; Iloprost; Immunologic Techniques; Isoproterenol; Molecular Sequence Data; Peptides; Propranolol; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Transfection | 1995 |
ATPo but not cAMPi activates a chloride conductance in mouse ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Isoproterenol; Membrane Potentials; Mice; Mice, Knockout; Myocardium; Patch-Clamp Techniques; Stimulation, Chemical | 1995 |
Regulation of the adenylyl cyclase signaling system in various types of cultured endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bucladesine; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; GTP-Binding Proteins; Histamine; Humans; Isoproterenol; Phosphoric Diester Hydrolases; Signal Transduction; Swine; Virulence Factors, Bordetella | 1995 |
Activity-induced facilitation of L-type Ca2+ current in cardiomyocytes isolated from guinea-pig ventricles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Barium; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Egtazic Acid; Guinea Pigs; Heart Ventricles; Isoproterenol; Male; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Phosphoric Diester Hydrolases; Sodium; Temperature | 1995 |
Inhibition of pituitary adenylate cyclase activating polypeptide induced relaxation of guinea-pig tracheal smooth muscle by charybdotoxin.
Topics: Animals; Charybdotoxin; Colforsin; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Scorpion Venoms; Trachea | 1995 |
Altered beta-adrenergic regulation of Na-K-Cl cotransport in cultured smooth muscle cells from the aorta of spontaneously hypertensive rats. Role of the cytoskeleton network.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cytoskeleton; Diuretics; Enzyme Inhibitors; Isoproterenol; Male; Membrane Proteins; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred SHR; Receptors, Adrenergic, beta; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Chloride Symporters | 1995 |
Interferon-gamma and lipopolysaccharide reduce cAMP responses in cultured glial cells: reversal by a type IV phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Enzyme Activation; Interferon-gamma; Isoproterenol; Lipopolysaccharides; Microglia; Neuroglia; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Time Factors | 1995 |
Mucociliary function in the mouse measured in explanted lung tissue.
Topics: Animals; Charcoal; Cilia; Colforsin; Culture Techniques; Hydrogen-Ion Concentration; Isoproterenol; Lung; Male; Mice; Mice, Inbred Strains; Mucociliary Clearance; Temperature | 1995 |
Potentiation of agonist-stimulated cyclic AMP accumulation by tyrosine kinase inhibitors in rat pinealocytes.
Topics: Animals; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Genistein; Isoflavones; Isoproterenol; Male; Norepinephrine; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pineal Gland; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley | 1995 |
Desensitization of myocardial beta-adrenergic receptors and deterioration of left ventricular function after brain death.
Topics: Adenylyl Cyclases; Animals; Brain Death; Colforsin; Cyclic AMP; Disease Models, Animal; GTP-Binding Proteins; Isoproterenol; Myocardium; Radioligand Assay; Receptors, Adrenergic, beta; Sodium Fluoride; Swine; Ventricular Function, Left | 1995 |
Complex intracellular signal transduction regulates tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type-1 (PAI-1) synthesis in cultured human umbilical vein endothelium.
Topics: Cells, Cultured; Colforsin; Endothelins; Endothelium, Vascular; Endotoxins; Ephedrine; Humans; Isoproterenol; Nitroprusside; Plasminogen Activator Inhibitor 1; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Tissue Plasminogen Activator; Umbilical Veins | 1995 |
Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; GTP-Binding Proteins; Heart Ventricles; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction | 1995 |
Functional desensitization of beta agonist responses in human lung mast cells.
Topics: Adrenergic beta-Agonists; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Drug Tolerance; Histamine Release; Humans; Isoproterenol; Lung; Mast Cells; Receptors, Adrenergic, beta; Signal Transduction | 1995 |
Ca(2+)-dependent and -independent mechanism of cyclic-AMP reduction: mediation by bradykinin B2 receptors.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Ionomycin; Isoproterenol; Male; Muscle, Smooth; Receptors, Bradykinin; Time Factors; Vas Deferens | 1995 |
Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Isoquinolines; Kidney; Kinetics; Models, Biological; Oscillometry; Phosphatidylinositols; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucagon; Signal Transduction; Time Factors | 1995 |
Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure.
Topics: Animals; Biochemical Phenomena; Biochemistry; Colforsin; Heart Failure; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Stimulation, Chemical | 1995 |
Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Base Sequence; Brimonidine Tartrate; Bucladesine; Catecholamines; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dioxanes; DNA Primers; Epididymis; Gene Expression; Idazoxan; Isoproterenol; Lipase; Lipolysis; Male; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger; Skin | 1995 |
Glibenclamide, an ATP-sensitive K+ channel blocker, inhibits cardiac cAMP-activated Cl- conductance.
Topics: Animals; Chloride Channels; Colforsin; Cyclic AMP; Electrophysiology; Glyburide; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phosphorylation | 1995 |
Desensitization of beta-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase.
Topics: Adipocytes; Animals; Colforsin; Cyclic AMP; Dobutamine; Dose-Response Relationship, Drug; Down-Regulation; Isoproterenol; Lipolysis; Male; Norepinephrine; Phosphoric Diester Hydrolases; Procaterol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1995 |
Beta-adrenergic mitogenic signal transduction in peripheral lung adenocarcinoma: implications for individuals with preexisting chronic lung disease.
Topics: Adenocarcinoma; Cell Division; Colforsin; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Lung Diseases; Lung Neoplasms; Mitogens; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Signal Transduction; Tumor Cells, Cultured | 1995 |
GTP requirement for isoproterenol activation of calcium channels in vascular myocytes.
Topics: Animals; Calcium Channels; Colforsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoproterenol; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rabbits; Thionucleotides | 1995 |
Regulation of signal transduction and DNA fragmentation in thymocytes by ethanol.
Topics: Animals; Apoptosis; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA Damage; Ethanol; Fluorometry; Isoproterenol; Mice; Mice, Inbred C57BL; Protein Kinase C; Signal Transduction; T-Lymphocytes; Thymus Gland | 1995 |
Colchicine and cytochalasin B enhance cyclic AMP accumulation via postreceptor actions.
Topics: Adenylyl Cyclases; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytoskeleton; GTP-Binding Proteins; Humans; Isoproterenol; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1995 |
Dexamethasone enhances the effects of parathyroid hormone on human periodontal ligament cells in vitro.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Humans; Isoproterenol; Kinetics; Osteoblasts; Parathyroid Hormone; Periodontal Ligament | 1995 |
Parathyroid hormone (PTH)/PTH-related protein receptor messenger ribonucleic acid expression and PTH response in a rat model of secondary hyperparathyroidism associated with vitamin D deficiency.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Membrane; Colforsin; Diaphyses; Disease Models, Animal; Femur; Food, Fortified; Hyperparathyroidism, Secondary; Isoproterenol; Kidney; Lactose; Male; Parathyroid Hormone; Phosphates; Rats; Rats, Wistar; Receptor, Parathyroid Hormone, Type 1; Receptors, Parathyroid Hormone; RNA, Messenger; Sodium Fluoride; Vitamin D; Vitamin D Deficiency | 1995 |
Adrenergic receptor-mediated Cl- transport in rabbit corneal endothelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetazolamide; Adrenergic Agonists; Adrenergic Antagonists; Affinity Labels; Animals; Brimonidine Tartrate; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorescent Dyes; Ion Transport; Isoproterenol; Microscopy, Fluorescence; Norepinephrine; Phentolamine; Phenylephrine; Photometry; Quinolines; Quinoxalines; Rabbits; Receptors, Adrenergic; Yohimbine | 1995 |
Regulation of beta 2-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells: effects of agonist, forskolin, and protein synthesis inhibition.
Topics: ADP Ribose Transferases; Adrenergic beta-2 Receptor Agonists; Animals; Bacterial Toxins; Base Sequence; Colforsin; DNA Primers; Down-Regulation; Exotoxins; Isoproterenol; Molecular Sequence Data; Protein Synthesis Inhibitors; Pseudomonas; Pseudomonas aeruginosa Exotoxin A; Rats; Receptors, Adrenergic, beta-2; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Virulence Factors | 1995 |
[3H]forskolin binding to cardiac adenylate cyclase in guinea pigs chronically infused with isoproterenol.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Female; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Myocardium; Sodium Fluoride | 1995 |
Subtype-specific regulation of muscarinic receptor expression and function by heterologous receptor activation.
Topics: Animals; Carbachol; Chick Embryo; Colforsin; Cyclic AMP; Gene Expression; Heart; Isoproterenol; Receptors, Adrenergic, beta; Receptors, Muscarinic; RNA, Messenger | 1995 |
Renin expression in renal proximal tubule.
Topics: Animals; Base Sequence; Blotting, Southern; Cells, Cultured; Cloning, Molecular; Colforsin; Enalapril; In Vitro Techniques; Isoproterenol; Kidney Tubules, Proximal; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligodeoxyribonucleotides; Poly A; Polymerase Chain Reaction; Rabbits; Rats; Rats, Sprague-Dawley; Renin; RNA; RNA, Messenger; Transcription, Genetic | 1993 |
The phagocytosis of rod outer segments is inhibited by drugs linked to cyclic adenosine monophosphate production.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Phagocytosis; Pigment Epithelium of Eye; Rats; Rats, Mutant Strains; Rod Cell Outer Segment | 1993 |
Functionally distinct phospho-forms underlie incremental activation of protein kinase-regulated Cl- conductance in mammalian heart.
Topics: Animals; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Activation; Ethers, Cyclic; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Ionophores; Isoproterenol; Membrane Proteins; Myocardium; Okadaic Acid; Protein Kinases | 1993 |
A pharmacological investigation of the contribution of muscarinic receptor-linked potassium channels to the reversal by carbachol of positive inotropic responses of rabbit left atrium to cyclic AMP-generating agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function, Left; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Depression, Chemical; Electric Stimulation; Female; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pertussis Toxin; Potassium Channels; Rabbits; Receptors, Muscarinic; Virulence Factors, Bordetella | 1993 |
Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Activation; Glomerular Mesangium; Isoproterenol; Kidney Glomerulus; Male; Pertussis Toxin; Protein Kinase C; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Infant, Newborn; Isoproterenol; Kinetics; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinases; Signal Transduction | 1993 |
Increasing cAMP attenuates activation of mitogen-activated protein kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epididymis; Glucagon; Isoenzymes; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Thionucleotides; Tyrosine | 1993 |
cAMP and protein synthesis in isolated adult rat heart preparations.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Epinephrine; Glucagon; Heart; Hypertension; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Perfusion; Phenylephrine; Phosphocreatine; Prazosin; Propranolol; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Yohimbine | 1993 |
Effects of adenylyl cyclase-linked neuropeptides on the expression of ciliary neurotrophic factor-mRNA in cultured astrocytes.
Topics: Adenylyl Cyclases; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Ciliary Neurotrophic Factor; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dopamine; Isoproterenol; Nerve Tissue Proteins; Neuropeptides; Olfactory Bulb; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; RNA, Messenger; Transcription, Genetic; Vasoactive Intestinal Peptide | 1995 |
The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine study.
Topics: Animals; Bacterial Toxins; Calcium; Carbachol; Chloride Channels; Cholera Toxin; Colforsin; Colon; Cyclic AMP; Cystic Fibrosis; Enterotoxins; Epithelium; Escherichia coli Proteins; Furosemide; Gastrointestinal Hormones; Glucose; Heterozygote; Ileum; Isoproterenol; Kallidin; Mice; Mice, Mutant Strains; Natriuretic Peptides; Peptides; Vasoactive Intestinal Peptide | 1995 |
Age-dependent alterations in beta-adrenergic responsiveness of rat detrusor smooth muscle.
Topics: Aging; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Urinary Bladder | 1995 |
Fat mobilisation in short days is not associated with altered noradrenergic sensitivity of adipocytes in Djungarian hamsters.
Topics: Adenylyl Cyclase Inhibitors; Adipocytes; Animals; Body Weight; Colforsin; Cricetinae; Fats; Isoproterenol; Lipolysis; Norepinephrine; Organ Size; Phodopus; Photoperiod; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, beta | 1995 |
Regulation of cyclic AMP production in adult human ciliary processes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Ciliary Body; Clonidine; Colforsin; Cyclic AMP; Endothelins; Humans; Isoproterenol; Stimulation, Chemical; Vasoactive Intestinal Peptide | 1995 |
Calcitonin gene-related peptide promotes Schwann cell proliferation.
Topics: Animals; Calcitonin Gene-Related Peptide; Cell Division; Cell Separation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Isoproterenol; Mitosis; Neprilysin; Platelet-Derived Growth Factor; Rats; Schwann Cells; Sciatic Nerve | 1995 |
Protamine does not affect the formation of cGMP or cAMP in pig vascular smooth muscle cells in response to vasodilators.
Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Muscle, Smooth, Vascular; Nitroprusside; Prospective Studies; Protamines; Swine; Vasodilator Agents | 1995 |
Modulation of cyclic AMP production by strial marginal cells from gerbil in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Alprostadil; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Endolymph; Epinephrine; Gerbillinae; Immunohistochemistry; Isoproterenol; Male; Microscopy, Electron; Stria Vascularis; Vasopressins | 1994 |
Effects of opioid substances on cAMP response to the beta-adrenergic agonist isoproterenol in human mononuclear leukocytes.
Topics: Adult; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoproterenol; Leukocytes, Mononuclear; Morphine; Opioid Peptides | 1995 |
Inhibitory pathway of cardiac PKA-dependent Cl- conductance via pertussis toxin-sensitive G proteins.
Topics: Adenylate Cyclase Toxin; Animals; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guinea Pigs; Heart; Isoproterenol; Patch-Clamp Techniques; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
Bovine hereditary cardiomyopathy: an animal model of human dilated cardiomyopathy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cardiomyopathies; Cardiomyopathy, Dilated; Catecholamines; Cattle; Cattle Diseases; Colforsin; Disease Models, Animal; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Heart Atria; Heart Ventricles; Humans; Isoproterenol; Manganese; Myocardial Contraction; Myocardium; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride; Ventricular Function, Right; Virulence Factors, Bordetella | 1995 |
Inflammation induced changes in adenosine 3',5'-cyclic monophosphate production by ciliary epithelial cell bilayers.
Topics: Animals; Ciliary Body; Colforsin; Culture Techniques; Cyclic AMP; Epithelium; Interleukin-1; Isoproterenol; Lipopolysaccharides; Male; Rabbits; Recombinant Proteins; Tumor Necrosis Factor-alpha; Uveitis, Anterior | 1995 |
Voltage-sensitive adenylyl cyclase activity in cultured neurons. A calcium-independent phenomenon.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Hippocampus; Ion Channel Gating; Isoproterenol; Mice; Neurons; Potassium Chloride; Rats; Veratridine | 1995 |
Effects of extracellular magnesium and beta adrenergic stimulation on contractile force and magnesium mobilization in the isolated rat heart.
Topics: Animals; Catecholamines; Colforsin; Cyclic AMP; Epinephrine; Female; Homeostasis; Isoproterenol; Magnesium; Male; Myocardial Contraction; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Spectrophotometry, Atomic; Verapamil | 1994 |
Activation of the Na+/H+ exchanger by cellular pH and extracellular Na+ in rat adipocytes; inhibition by isoproterenol.
Topics: Adipocytes; Amiloride; Animals; Carrier Proteins; Colforsin; Cyclic AMP; Hydrogen-Ion Concentration; Isoproterenol; Male; Nigericin; Rats; Rats, Sprague-Dawley; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Theophylline | 1995 |
C-natriuretic peptide but not atrial natriuretic peptide increases cyclic GMP in cerebral arterial smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Cerebral Arteries; Colforsin; Coronary Vessels; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Proteins; Swine | 1995 |
Actions of isoproterenol in frog proximal tubules.
Topics: 4-Aminopyridine; Adenylyl Cyclases; Alprenolol; Amiloride; Animals; Cell Fusion; Colforsin; Cyclic AMP; Giant Cells; In Vitro Techniques; Isoproterenol; Kidney Tubules, Proximal; Kinetics; Membrane Potentials; Potassium; Rana ridibunda; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Noradrenergic enhancement of GABA-induced input resistance changes in layer V regular spiking pyramidal neurons of rat somatosensory cortex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Isoproterenol; Membrane Potentials; Microelectrodes; Muscimol; Norepinephrine; Pyramidal Cells; Rats; Somatosensory Cortex | 1995 |
Cyclic AMP-dependent modulation of interleukin-1 receptors in the mouse AtT-20 pituitary tumor cell line.
Topics: Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Isoproterenol; Mice; Pituitary Neoplasms; Receptors, Interleukin-1; Somatostatin; Tumor Cells, Cultured | 1994 |
The phospholipase C activating P2U purinoceptor also inhibits cyclicAMP formation in DDT1 MF-2 smooth muscle cells.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Isoproterenol; Male; Muscle, Smooth; Pertussis Toxin; Receptors, Purinergic P2; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella | 1994 |
Adenosine A1-receptor mechanisms antagonize beta-adrenergic pulmonary vasodilation in hypoxia.
Topics: Adenosine; Animals; Colforsin; Isoproterenol; Oxygen; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Vasodilation | 1994 |
Calcium current in rat diabetic ventricular myocytes.
Topics: Action Potentials; Animals; Blood Glucose; Body Weight; Calcium Channels; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Electric Conductivity; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Ventricles; Isoproterenol; Kinetics; Male; Myocardial Contraction; Rats; Rats, Wistar | 1994 |
Adrenergic regulation of coronary microcirculation after extracorporeal circulation and crystalloid cardioplegia.
Topics: Adenosine; Animals; Cardioplegic Solutions; Cardiopulmonary Bypass; Colforsin; Coronary Circulation; Crystallization; Extracorporeal Circulation; Female; Heart Arrest, Induced; Isoproterenol; Male; Microcirculation; Nitroprusside; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium Fluoride; Swine; Vasodilation | 1994 |
Independent and coordinate regulation of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells.
Topics: Animals; Astrocytes; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Isoproterenol; Oligodendroglia; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Tumor Cells, Cultured | 1994 |
Effect of diabetes mellitus on responses of the rat basilar artery to activation of beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Animals; Basilar Artery; Colforsin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Isoproterenol; Norepinephrine; Rats; Receptors, Adrenergic, beta; Reference Values; Vasodilation | 1994 |
cAMP accumulation in T-cells inhibits anti-CD3 monoclonal antibody-induced actin polymerization.
Topics: Actins; Antibodies, Monoclonal; Bucladesine; CD3 Complex; Colforsin; Cyclic AMP; Humans; Isoproterenol; Receptors, Adrenergic, beta; T-Lymphocytes | 1995 |
Characterization of the adenosine receptor in microvascular coronary endothelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antihypertensive Agents; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Isoproterenol; Myocardium; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Thioinosine; Vasodilator Agents | 1994 |
Characterization of cloned human dopamine D1 receptor-mediated calcium release in 293 cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepines; Calcium; Cells, Cultured; Cholera Toxin; Cloning, Molecular; Colforsin; Cyclic AMP; Dopamine; Humans; Hydrolysis; Intracellular Fluid; Isoproterenol; Kinetics; Phosphatidylinositols; Receptors, Dopamine D1; Stimulation, Chemical; Tritium | 1995 |
cAMP-dependent activation of ion conductances in bronchial epithelial cells.
Topics: Bronchi; Chlorides; Colforsin; Cyclic AMP; Electric Conductivity; Epithelium; Histamine; Humans; Ions; Isoproterenol | 1994 |
Catecholamine-induced cAMP response in streptozotocin-induced diabetic rat liver.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Emaciation; Epinephrine; Glucagon; Glucose; Insulin; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Oxymetazoline; Phenylephrine; Propranolol; Pyruvates; Pyruvic Acid; Rats; Receptors, Adrenergic, beta; Streptozocin | 1994 |
Participation of tubulin in the stimulatory regulation of adenylyl cyclase in rat cerebral cortex membranes.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Tubulin | 1995 |
Phosphorylation by protein kinase A enhances delayed rectifier K+ current in rabbit vascular smooth muscle cells.
Topics: 4-Aminopyridine; Adenylyl Imidodiphosphate; Animals; Cell Separation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; Muscle, Smooth, Vascular; Phosphorylation; Potassium; Rabbits | 1995 |
Multiple mechanisms in the smooth muscle relaxant action of calcitonin gene-related peptide (CGRP) in the guinea-pig ureter.
Topics: Action Potentials; Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitroarginine; Parasympatholytics; Pyrroles; Ureter | 1994 |
Differential effects of phosphodiesterase inhibitors on accumulation of cyclic AMP in isolated ventricular cardiomyocytes.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Enoximone; Imidazoles; Isoenzymes; Isoproterenol; Male; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridines; Rats; Rats, Sprague-Dawley | 1995 |
Influence of ischaemia and reperfusion on cardiac signal transduction. G protein content, adenylyl cyclase activity, cyclic AMP content, and forskolin and dibutyryl cyclic AMP-induced inotropy in the rat Langendorff heart.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Heart; In Vitro Techniques; Ischemia; Isoproterenol; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Signal Transduction | 1994 |
Regulation of histamine- and UTP-induced increases in Ins(1,4,5)P3, Ins (1,3,4,5)P4 and Ca2+ by cyclic AMP in DDT1 MF-2 cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Histamine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Male; Mesocricetus; Muscle, Smooth; Receptors, Histamine H1; Receptors, Purinergic P2; Type C Phospholipases; Uridine Triphosphate; Vas Deferens | 1995 |
Loss of response to beta-adrenoceptor agonists during the maturation of human monocytes to macrophages in vitro.
Topics: Acetylglucosaminidase; Adenylyl Cyclases; Cell Differentiation; Colforsin; Enzyme Activation; Humans; In Vitro Techniques; Isoproterenol; Macrophages; Monocytes; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride; Thromboxane B2; Zymosan | 1995 |
Isoproterenol inhibits rod outer segment phagocytosis by both cAMP-dependent and independent pathways.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Isoproterenol; Phagocytosis; Pigment Epithelium of Eye; Protein Kinase Inhibitors; Rats; Rod Cell Outer Segment; Stereoisomerism; Thionucleotides | 1995 |
Beta-adrenergic modulation of glial inwardly rectifying potassium channels.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activation; Epinephrine; Isoproterenol; Neuroglia; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1995 |
Effects of second messengers on the permeability and morphology of eel rete capillaries.
Topics: Albumins; Animals; Bucladesine; Calcimycin; Calcium; Capillaries; Capillary Permeability; Colforsin; Diglycerides; Eels; Isoproterenol; Microscopy, Electron; Nucleotides, Cyclic; Phosphatidylinositols; Second Messenger Systems; Sodium; Sucrose; Tetradecanoylphorbol Acetate | 1995 |
Contribution of Na(+)-Ca2+ exchange to stimulation of transient inward current by isoproterenol in rabbit cardiac Purkinje fibers.
Topics: Animals; Calcium; Chlorides; Colforsin; In Vitro Techniques; Isoproterenol; Phosphorylation; Propranolol; Purkinje Fibers; Rabbits; Sodium; Stimulation, Chemical | 1995 |
Mechanisms of cyclic nucleotide-induced relaxation in canine tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Sarcoplasmic Reticulum; Trachea | 1995 |
Positive coupling of beta-like adrenergic receptors with adenylate cyclase in the cnidarian Renilla koellikeri.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Atenolol; Cholera Toxin; Cnidaria; Colforsin; Fluorides; Guanine Nucleotides; Isoproterenol; Neurotransmitter Agents; Receptors, Adrenergic, beta; Signal Transduction; Theophylline; Trifluoperazine | 1993 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Physiological desensitization of beta 3-adrenergic responses in brown fat cells: involvement of a postreceptor process.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Acclimatization; Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cells, Cultured; Cold Temperature; Colforsin; Cricetinae; Cyclic AMP; Ethanolamines; Isoproterenol; Kinetics; Male; Mesocricetus; Norepinephrine; Oxygen Consumption; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1993 |
Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
Topics: Animals; Calcium Channels; Colforsin; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Heart Ventricles; In Vitro Techniques; Isoproterenol; Molsidomine; Nitric Oxide; Phosphoric Diester Hydrolases; Rana esculenta | 1993 |
Enhancement of NMDA receptor-mediated synaptic potential by isoproterenol is blocked by Rp-adenosine 3',5'-cyclic monophosphothioate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Evoked Potentials; In Vitro Techniques; Isoproterenol; Neurons; Picrotoxin; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Thionucleotides | 1993 |
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms.
Topics: Adenylyl Imidodiphosphate; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horses; Ion Channel Gating; Isoproterenol; Kinetics; Membrane Potentials; Muscle, Smooth; Potassium Channels; Trachea | 1994 |
Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Colforsin; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Propanolamines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Somatostatin; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1993 |
Beta 1 adrenoceptor mediated decrease in pHi in quiescent ventricular myocardium.
Topics: Adrenergic beta-Antagonists; Amiloride; Animals; Atenolol; Colforsin; Culture Techniques; Female; Guinea Pigs; Heart Ventricles; Hydrogen-Ion Concentration; Isoproterenol; Male; Membrane Potentials; Myocardium; Phenylephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Stimulation, Chemical | 1994 |
Activation and depalmitoylation of Gs alpha.
Topics: Adrenergic beta-Agonists; Animals; Cell Compartmentation; Cell Line; Cell Membrane; Colforsin; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Isoproterenol; Mice; Palmitates; Protein Processing, Post-Translational; Signal Transduction | 1994 |
Characterisation of the beta adrenergic response cascade in fetal guinea pig lung.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Choline; Colforsin; Cyclic AMP; Gestational Age; Guinea Pigs; Isoproterenol; Lung; Models, Biological; Phosphatidylcholines; Pindolol; Radioimmunoassay; Receptors, Adrenergic, beta | 1994 |
Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Glycerol; Isoproterenol; Kinetics; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Binding Sites; Bronchi; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Humans; Isoproterenol; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Mediation of most atypical effects by species homologues of the beta 3-adrenoceptor.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; CHO Cells; Colforsin; Cricetinae; Epinephrine; Humans; Iodocyanopindolol; Isoproterenol; Ligands; Mice; Norepinephrine; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Species Specificity | 1994 |
Effect of glibenclamide, forskolin, and isoprenaline on the parallel activation of KATP and reduction of IK by cromakalim in cardiac myocytes.
Topics: Animals; Benzopyrans; Cells, Cultured; Colforsin; Cromakalim; Glyburide; Guinea Pigs; Isoproterenol; Myocardium; Potassium Channels; Pyrroles; Sodium-Potassium-Exchanging ATPase; Vasodilator Agents | 1994 |
Chloride dependence of pH modulation by beta-adrenergic agonist in rat cardiomyocytes.
Topics: Adenosine; Animals; Antiporters; Bicarbonates; Bucladesine; Chloride-Bicarbonate Antiporters; Chlorides; Colforsin; Cyclic AMP; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1994 |
Modulation of adenylylcyclase by protein kinase C in human neurotumor SK-N-MC cells: evidence that the alpha isozyme mediates both potentiation and desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alkaloids; Aluminum Compounds; Animals; Brain; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fluorides; GTP-Binding Proteins; Humans; Isoenzymes; Isoproterenol; Kinetics; Manganese; Neuroblastoma; Neuropeptide Y; Propanolamines; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Agonist and cyclic AMP-mediated regulation of beta 1-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP; Down-Regulation; Endotoxins; Glioma; Isoproterenol; Rats; Receptors, Adrenergic, beta-1; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Postnatal development of vascular beta-adrenoceptor-mediated responses and the increase in the adrenaline content of the adrenal gland have a parallel time course.
Topics: Adrenal Glands; Animals; Animals, Newborn; Colforsin; Dogs; Epinephrine; Female; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Adrenergic, beta | 1994 |
Adrenergic receptor-mediated regulation of cultured rabbit airway smooth muscle cell proliferation.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Muscle, Smooth; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thionucleotides; Trachea | 1994 |
Mechanisms mediating responsiveness to beta-adrenergic stimulation after coronary reperfusion in conscious dogs.
Topics: Amino Acid Sequence; Animals; Blood Pressure; Colforsin; Coronary Vessels; Dogs; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Heart; Heart Rate; Hemodynamics; Isoproterenol; Male; Molecular Sequence Data; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Peptide Fragments; Receptors, Adrenergic, beta; Signal Transduction; Time Factors; Ventricular Function, Left | 1994 |
Potential-dependent Ca2+ currents in isolated heart cells of hibernators.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Electric Conductivity; Electrophysiology; Gallopamil; Heart; Hibernation; Isoproterenol; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Sciuridae | 1994 |
Role of cyclic AMP-induced Cl conductance in aqueous humour formation by the dog ciliary epithelium.
Topics: Animals; Aqueous Humor; Bucladesine; Chloride Channels; Ciliary Body; Colforsin; Cyclic AMP; Dogs; Epithelium; Female; Isoproterenol; Male | 1994 |
Cellular and molecular alterations in the beta adrenergic system with cardiomyopathy induced by tachycardia.
Topics: Adenylyl Cyclases; Animals; Cardiomyopathies; Cell Size; Colforsin; GTP-Binding Proteins; Isoproterenol; Myocardium; Receptors, Adrenergic, beta; Swine; Tachycardia, Supraventricular | 1994 |
Short-term exposure of intact ventricular myocytes to isoproterenol results in desensitization of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Heart; Isoproterenol; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors | 1994 |
Natriuretic peptide clearance receptor is transcriptionally down-regulated by beta 2-adrenergic stimulation in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Cell Membrane; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Gene Expression; Guanylate Cyclase; Isoproterenol; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Norepinephrine; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Sodium Fluoride | 1994 |
Neuropeptide Y inhibits vasoactive intestinal peptide-stimulated adenylyl cyclase in rat ventral prostate.
Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Fluorescence Polarization Immunoassay; GTP-Binding Proteins; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Male; Membrane Lipids; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Prostate; Rats; Rats, Wistar; Swine; Vasoactive Intestinal Peptide | 1994 |
Developmental changes in the actions of phosphatase inhibitors on calcium current of rabbit heart cells.
Topics: Animals; Animals, Newborn; Calcium Channels; Colforsin; Cyclic AMP; Ethers, Cyclic; Female; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Microcystins; Myocardium; Okadaic Acid; Patch-Clamp Techniques; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Rabbits | 1994 |
Diverse G protein and beta-adrenergic receptor mRNA expression in normal and failing porcine hearts.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Membrane; Cloning, Molecular; Colforsin; DNA Primers; Female; Gene Expression; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Heart Failure; Heart Ventricles; Isoproterenol; Molecular Sequence Data; Myocardium; Polymerase Chain Reaction; Receptors, Adrenergic, beta; Reference Values; RNA, Messenger; Swine; Transcription, Genetic | 1994 |
Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension.
Topics: Adenylyl Cyclases; Adult; Blood Pressure; Case-Control Studies; Cholera Toxin; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Heart Rate; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Middle Aged; Radioligand Assay; Receptors, Adrenergic, beta | 1994 |
Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Benzoxazines; CD18 Antigens; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytoplasmic Granules; Endothelium, Vascular; Humans; Infant, Newborn; Isoproterenol; Macrophage-1 Antigen; Milrinone; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxazines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyridones; Pyrrolidinones; Respiratory Burst; Rolipram; Umbilical Veins | 1995 |
Isoproterenol and 8-bromo-cyclic adenosine monophosphate stimulate the expression of the angiotensinogen gene in opossum kidney cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensinogen; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Female; Gene Expression Regulation; Isoproterenol; Kidney Tubules, Proximal; Opossums; Recombinant Fusion Proteins; Transfection | 1994 |
Influence of exercise training on myocardial beta-adrenergic signal transduction: differential regulation with age.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Heart; Isoproterenol; Myocardium; Organ Size; Oxygen Consumption; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenylyl Cyclases; Animals; Capillary Permeability; Colforsin; Image Processing, Computer-Assisted; Isoproterenol; Lung; Male; Pulmonary Circulation; Pyrrolidinones; Rats; Rats, Inbred Strains; Reperfusion Injury; Rolipram | 1994 |
Effects of cyclic AMP and analogues on neurogenic transmission in the rat tail artery.
Topics: Animals; Arteries; Colforsin; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle, Smooth, Vascular; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Synaptic Transmission; Tail; Vasoconstriction | 1994 |
Modulation of cardiac L-type Ca2+ channels by GTP gamma S in response to isoprenaline, forskolin and photoreleased nucleotides.
Topics: Animals; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Isoproterenol; Myocardium; Photolysis; Protein Kinase Inhibitors; Thionucleotides | 1994 |
Protein kinase-dependent Cl- currents in feline ventricular myocytes.
Topics: Animals; Cats; Chloride Channels; Chlorides; Colforsin; Electrophysiology; Isoproterenol; Myocardium; Osmolar Concentration; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Ventricular Function | 1994 |
Enhancement of ATP-sensitive potassium current in cat ventricular myocytes by beta-adrenoreceptor stimulation.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cats; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Isoproterenol; Myocardium; Potassium; Potassium Channels; Receptors, Adrenergic, beta | 1994 |
Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and beta-adrenergic agonists.
Topics: Adenylyl Cyclases; Animals; Chickens; Colforsin; Cyclic AMP; Enzyme Activation; Epinephrine; Female; Guanylyl Imidodiphosphate; Isoproterenol; Luteinizing Hormone; Ovary; Progesterone; Propranolol; Sodium Fluoride | 1994 |
Effect of captopril on lymphocytic beta-adrenergic receptors in normal and hypoxic conditions.
Topics: Adult; Captopril; Cell Hypoxia; Cells, Cultured; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta | 1994 |
Uncoupling of coronary microvascular beta 2-adrenoceptors by Escherichia coli endotoxemia.
Topics: Animals; Colforsin; Coronary Vessels; Escherichia coli; Hemodynamics; Isoproterenol; Lipopolysaccharides; Male; Microcirculation; Receptors, Adrenergic, beta-2; Swine | 1994 |
Defective glomerular beta-adrenergic signal transmission in spontaneously diabetic rats.
Topics: Animals; Blood Glucose; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 1; Dinoprostone; Histamine; Isoproterenol; Kidney Glomerulus; Rats; Rats, Inbred BB; Rats, Mutant Strains; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Transforming growth factor beta-1 modulates the number of beta-adrenergic receptors in cardiac fibroblasts.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; Isoproterenol; Myocardium; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Transforming Growth Factor beta | 1994 |
Characterization of cyclic AMP accumulation in cultured human corpus cavernosum smooth muscle cells.
Topics: Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Penis; Receptors, Adrenergic, beta | 1994 |
Relationship between cAMP production and protein secretion in rat submandibular acini: evidence for loss of reserve capacity with age.
Topics: Aging; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred F344; Reference Values; Salivary Proteins and Peptides; Submandibular Gland | 1994 |
The in-vitro effects of insulin and the effects of acute fasting on cardiac beta-adrenoceptor responses in the short-term streptozotocin-diabetic rat.
Topics: Analysis of Variance; Animals; Blood Glucose; Colforsin; Diabetes Mellitus, Experimental; Dihydroalprenolol; Fasting; Female; Heart; In Vitro Techniques; Insulin; Isoproterenol; Myocardium; Papillary Muscles; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Streptozocin | 1994 |
Costimulatory signals modulate the antiproliferative effects of agents that elevate cAMP in T cells.
Topics: Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Bucladesine; CD28 Antigens; CD3 Complex; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Humans; Immunosuppressive Agents; Interleukin-2; Isoproterenol; Lymphocyte Activation; Signal Transduction; T-Lymphocytes | 1994 |
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Guanylate Cyclase; Isoproterenol; Kinetics; Mice; Norepinephrine; Organ Culture Techniques; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1993 |
Alteration in Gs-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules.
Topics: Adenylyl Cyclases; Catalysis; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Lymphoma; Microtubules; Signal Transduction; Somatostatin; Tumor Cells, Cultured; Vinblastine | 1993 |
Alpha 2-adrenergic, but not imidazole, agonists activate NaCl cotransport in rabbit tracheal epithelial cells.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Carrier Proteins; Cells, Cultured; Chloride-Bicarbonate Antiporters; Clonidine; Colforsin; Cyclic AMP; Drug Interactions; Epithelial Cells; Epithelium; Guanabenz; Imidazoles; Imidazoline Receptors; Iodine Radioisotopes; Isoproterenol; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Second Messenger Systems; Sodium Chloride Symporters; Symporters; Thromboxane-A Synthase; Trachea | 1993 |
Beta-adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Colforsin; Cyclic AMP; Dobutamine; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Propranolol; Rats; Rats, Inbred WKY; Vascular Resistance | 1993 |
Transfected Go1 alpha inhibits the calcium dependence of beta-adrenergic stimulated cAMP accumulation in C6 glioma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Southern; Calcium; Cell Membrane Permeability; Colforsin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; GTP-Binding Proteins; Isoproterenol; Kinetics; Neuroglia; Rats; Transfection; Tumor Cells, Cultured | 1993 |
Opiate receptor agonists regulate phosphorylation of synapsin I in cocultures of rat spinal cord and dorsal root ganglion.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cell Communication; Cells, Cultured; Colforsin; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Ganglia, Spinal; Isoproterenol; Kinetics; Male; Morphine; Naloxone; Neurons; Phosphates; Phosphoproteins; Phosphorylation; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Serotonin; Spinal Cord; Synapsins; Synaptosomes | 1993 |
Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoproterenol; Male; Milrinone; Myocardial Ischemia; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Quinolines; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Altered beta-adrenergic receptor-stimulated cAMP formation in cultured skin fibroblasts from Alzheimer donors.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Aged; Alzheimer Disease; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; GTP-Binding Proteins; Humans; Isoproterenol; Middle Aged; Pertussis Toxin; Receptors, Adrenergic, beta; Signal Transduction; Skin; Virulence Factors, Bordetella | 1993 |
Ca(++)-independent relaxation mediated by beta adrenoceptor in Ca(++)-independent contraction of uterine smooth muscle.
Topics: Adrenergic beta-Antagonists; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Female; Intracellular Fluid; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Potassium; Potassium Channels; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Uterine Contraction | 1993 |
Paradoxical regulation of dopamine receptors in transfected 293 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apomorphine; Cell Line; Colforsin; Corpus Striatum; Cyclic AMP; DNA; Dopamine; Dopamine Agents; Dopamine Antagonists; Humans; Isoproterenol; Radioligand Assay; Rats; Receptors, Dopamine D2; Transfection | 1993 |
The effectiveness of beta-adrenoceptor stimulation and the contribution of beta 1-adrenoceptors increase from the proximal to the distal part of the canine saphenous vein.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Colforsin; Dobutamine; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Propanolamines; Receptors, Adrenergic, beta; Saphenous Vein; Terbutaline | 1993 |
Beta-adrenoceptor desensitization by/clenbuterol in rat uterus.
Topics: Adrenergic beta-Antagonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Estradiol; Female; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Relaxation; Phentolamine; Potassium Chloride; Rats; Rats, Wistar; Uterus | 1993 |
Isoproterenol stimulates Cl- current by a Gs protein-mediated process in beta-intercalated cells isolated from rabbit kidney.
Topics: Animals; Arachis; Atenolol; Calcium; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Enzyme Activation; Female; GTP-Binding Proteins; Intracellular Fluid; Isoproterenol; Kidney; Lectins; Membrane Potentials; Peanut Agglutinin; Plant Lectins; Protein Binding; Protein Kinases; Rabbits; Signal Transduction | 1993 |
Secretion of ions and pharmacological responsiveness in the mouse paw sweat gland.
Topics: Aging; Animals; Colforsin; Culture Techniques; Cyclic AMP; Eccrine Glands; Forelimb; Isoproterenol; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Potassium; Sodium | 1994 |
Regulation of ciliary neurotrophic factor in cultured rat hippocampal astrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Cells, Cultured; Ciliary Neurotrophic Factor; Colforsin; Cyclic AMP; Fibroblast Growth Factor 2; Gene Expression; Gene Expression Regulation; Hippocampus; Immunohistochemistry; Insulin-Like Growth Factor I; Isoproterenol; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Rats; RNA, Messenger; Time Factors | 1994 |
[Hormonal regulation of carbohydrate metabolism in the liver in plague intoxication].
Topics: Adenylyl Cyclases; Animals; Bacterial Toxins; Blood Glucose; Carbohydrate Metabolism; Colforsin; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Liver Glycogen; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yersinia pestis | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
Differential modulation by adenylate cyclase of Ca2+ and delayed K+ current in ventricular myocytes.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium; Colforsin; Electrophysiology; Guinea Pigs; Isoproterenol; Isotonic Solutions; Male; Myocardium; Potassium; Ventricular Function | 1994 |
Growth hormone increases the lipolytic sensitivity for catecholamines in adipocytes from healthy adults.
Topics: Adipocytes; Adipose Tissue; Adult; Bucladesine; Cholecystectomy; Colforsin; Cycloheximide; Dose-Response Relationship, Drug; Drug Synergism; Female; Growth Hormone; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lipolysis; Male; Recombinant Proteins; Reference Values | 1994 |
The effects of theophylline on aequorin light transients and force in the isolated dog right ventricular myocardium.
Topics: Aequorin; Animals; Calcium; Colforsin; Dogs; Female; Isometric Contraction; Isoproterenol; Male; Membrane Potentials; Temperature; Theophylline; Ventricular Function, Right | 1994 |
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; Isoproterenol; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Osmolar Concentration; Rabbits | 1993 |
Effects of receptor agonists on polyamine concentrations and spermidine/spermine N1-acetyltransferase activity in rat parotid gland.
Topics: Acetyltransferases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Female; Isoproterenol; Male; Parotid Gland; Pilocarpine; Putrescine; Rats; Signal Transduction | 1993 |
Lysophosphatidic acid mimics serum-induced sensitization of cyclic AMP accumulation.
Topics: Alprostadil; Animals; Astrocytoma; Blood; Colforsin; Cyclic AMP; Drug Interactions; Glioma; Humans; Isoproterenol; Lysophospholipase; Lysophospholipids; Pertussis Toxin; Phospholipases; Rats; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh).
Topics: Adenylyl Cyclases; B-Lymphocytes; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Gene Expression Regulation, Enzymologic; Genes, myc; Growth Inhibitors; Homeostasis; Humans; Isoenzymes; Isoproterenol; RNA, Messenger; Transcription, Genetic | 1993 |
The transduction system in the isoproterenol activation of the Ca(2+)-activated K+ channel in guinea pig taenia coli myocytes.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Colon; Cyclic AMP-Dependent Protein Kinases; Gallic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Guinea Pigs; Isoproterenol; Membrane Potentials; Muscles; Potassium Channels; Protein Kinase C; Signal Transduction; Staurosporine; Thionucleotides | 1993 |
Effects of hydrogen peroxide on stimulatory guanine nucleotide-binding protein in rat heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dihydroalprenolol; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; Hydrogen Peroxide; In Vitro Techniques; Isoproterenol; Lymphoma; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1993 |
Mechanism of isoprenaline-stimulated diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Bucladesine; Cells, Cultured; Colforsin; Diglycerides; In Vitro Techniques; Isoproterenol; Kinetics; Male; Parotid Gland; Phentolamine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Propranolol; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Staurosporine; Stimulation, Chemical; Vasoactive Intestinal Peptide | 1993 |
Arteriolar tone is determined by activity of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Arterioles; Benzopyrans; Bucladesine; Colforsin; Cricetinae; Cromakalim; Epoprostenol; Glyburide; Guanidines; Isoproterenol; Male; Mesocricetus; Methacholine Chloride; Muscle Tonus; Muscle, Smooth, Vascular; Muscles; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Quaternary Ammonium Compounds; Vasoconstriction; Vasodilation; Vasodilator Agents | 1993 |
Estrogen uncouples beta-adrenergic receptor from the stimulatory guanine nucleotide-binding protein in female rat hypothalamus.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Estradiol; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypothalamus; Isoproterenol; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Uncoupling Agents | 1993 |
Regulation of Ca2+ current in frog ventricular cardiomyocytes by guanosine 5'-triphosphate analogues and isoproterenol.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Rana catesbeiana | 1993 |
ucb 11056, a new potential nootropic drug, amplifies induced cyclic AMP formation in rat brain tissue.
Topics: Analysis of Variance; Animals; Brain; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Male; Morpholines; Propranolol; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Time Factors; Triazines; Yohimbine | 1993 |
Ischemic preconditioning is associated with a delay in ischemia-induced reduction of beta-adrenergic signal transduction in rabbit hearts.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pertussis Toxin; Rabbits; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Sarcolemma; Signal Transduction; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Virulence Factors, Bordetella | 1993 |
Isoproterenol- and insulin-induced hyperpolarization in rat skeletal muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Insulin; Isoproterenol; Male; Membrane Potentials; Muscles; Ouabain; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Beta-adrenergic enhancement of inhibitory synaptic activity in rat cerebellar stellate and Purkinje cells.
Topics: Action Potentials; Animals; Cerebellum; Colforsin; gamma-Aminobutyric Acid; In Vitro Techniques; Isoproterenol; Kinetics; Norepinephrine; Purkinje Cells; Rats; Receptors, Adrenergic, beta; Synapses; Tetrodotoxin | 1993 |
2,3,7,8-tetrachlorodibenzo-p-dioxin increases cardiac myocyte intracellular calcium and progressively impairs ventricular contractile responses to isoproterenol and to calcium in chick embryo hearts.
Topics: Animals; Calcium; Cells, Cultured; Chick Embryo; Colforsin; Drug Antagonism; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Phenobarbital; Polychlorinated Dibenzodioxins; Potassium; Theophylline | 1993 |
Responses of cerebral arterioles to activation of beta-adrenergic receptors during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Rats; Receptors, Adrenergic, beta; Vasodilation | 1994 |
[The effect of 1-isoproterenol on monovalent cation transport in activated human lymphocytes].
Topics: Biological Transport, Active; Cations, Monovalent; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lymphocyte Activation; Ouabain; Potassium; Rubidium; Sodium; T-Lymphocytes; Time Factors | 1993 |
cAMP-induced changes of intracellular free Mg2+ levels in human erythrocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Colforsin; Cyclic AMP; Diphosphoglyceric Acids; Erythrocytes; Humans; In Vitro Techniques; Isoproterenol; Isoquinolines; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Guanine nucleotide regulatory protein alterations in young Milan hypertensive strain rats.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Colforsin; GTP-Binding Proteins; Hypertension; Immune Sera; Isoproterenol; Molecular Sequence Data; Muscle, Smooth, Vascular; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction | 1994 |
Endotoxin disrupts beta-adrenergic signal transduction in the heart.
Topics: Adenylyl Cyclases; Animals; Cardiac Output; Colforsin; Cyclic AMP; Endotoxins; Heart; Heart Rate; Isoproterenol; Lipopolysaccharides; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Salmonella typhimurium; Signal Transduction; Ventricular Pressure | 1994 |
Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Guanosine Triphosphate; Isoproterenol; Mice; Molecular Sequence Data; Phorbol Esters; Protein Kinase C; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction | 1994 |
Postnatal decrease in muscarinic cholinergic influence on Ca2+ currents of rabbit ventricular cells.
Topics: Adenylate Cyclase Toxin; Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carbachol; Colforsin; Electric Conductivity; Female; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Male; Myocardium; Pertussis Toxin; Rabbits; Receptors, Muscarinic; Virulence Factors, Bordetella | 1993 |
Endotoxin-exposed atria exhibit G protein-based deficits in inotropic regulation.
Topics: Acetylcholine; Animals; Atrial Function; Colforsin; Endotoxins; GTP-Binding Proteins; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Changes in adenylyl cyclase activity in human endometrium during the menstrual cycle and in human decidua during pregnancy.
Topics: Adenylyl Cyclases; Adult; Colforsin; Corpus Luteum; Culture Techniques; Decidua; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Fallopian Tubes; Female; Humans; Isoproterenol; Menstrual Cycle; Middle Aged; Myometrium; Pregnancy | 1993 |
Implication of ATP released from atrial, but not papillary, muscle segments of guinea pig by isoproterenol and forskolin.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Colforsin; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Verapamil | 1993 |
Isoproterenol stimulates rapid extrusion of sodium from isolated smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Bufo marinus; Carbachol; Colforsin; Ethers, Cyclic; Fluorescent Dyes; Gastric Mucosa; In Vitro Techniques; Isoproterenol; Kinetics; Microscopy, Fluorescence; Muscle, Smooth; Ouabain; Pindolol; Potassium; Sodium; Stomach; Time Factors | 1993 |
Endothelins modulate dibutyryl cAMP-induced stellation of cultured astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Bucladesine; Calcium; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Egtazic Acid; Endothelins; Isoproterenol; Kinetics; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors; Viper Venoms | 1993 |
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.
Topics: Adult; Base Sequence; beta-Adrenergic Receptor Kinases; Binding, Competitive; Calcium; Cardiac Output, Low; Cardiomyopathy, Dilated; Colforsin; Coronary Disease; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Molecular Sequence Data; Myocardial Contraction; Oligonucleotide Probes; Papillary Muscles; Polymerase Chain Reaction; Protein Kinases; Receptors, Adrenergic, beta; RNA, Messenger | 1993 |
Overexpression of the intact thyrotropin receptor in a human thyroid carcinoma cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Blotting, Northern; Blotting, Southern; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Humans; Isoproterenol; Kinetics; Receptors, Thyrotropin; Recombinant Proteins; RNA, Messenger; Thyroid Neoplasms; Thyrotropin; Time Factors; Transfection; Tumor Cells, Cultured | 1993 |
Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Glioma; HIV Envelope Protein gp120; Humans; Isoproterenol; Kinetics; Mesoderm; Phosphoproteins; Phosphorylation; Propranolol; Rats; Receptors, Adrenergic, beta; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vimentin | 1993 |
Beta 2-adrenoceptor desensitization in cultured human airway smooth muscle.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Humans; Isoproterenol; Muscle, Smooth; Receptors, Adrenergic, beta; Time Factors | 1993 |
Structural and functional characterization of striated ducts isolated from the rabbit mandibular salivary gland.
Topics: Acetylcholine; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Histological Techniques; In Vitro Techniques; Isoproterenol; Male; Microscopy, Electron; Norepinephrine; Phenylephrine; Rabbits; Submandibular Gland | 1993 |
Downregulation of cardiac guanosine 5'-triphosphate-binding proteins in right atrium and left ventricle in pacing-induced congestive heart failure.
Topics: Adenylyl Cyclases; Animals; Blood Pressure; Cell Membrane; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Heart Failure; Heart Rate; Heart Ventricles; Isoproterenol; Liver; Myocardium; Organ Size; Reference Values; Sodium Fluoride; Swine | 1993 |
Pharmacological analysis of vasodilation induced by extracellular adenosine 3',5'-cyclic monophosphate in the isolated and perfused canine coronary artery.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Isoproterenol; Male; Perfusion; Vasodilation | 1993 |
Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; Hydrolysis; Isoproterenol; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1993 |
Interaction of VIP, PACAP and related peptides in normal and leukemic human monocytes and macrophages.
Topics: Adenylyl Cyclases; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Hydrogen Peroxide; Isoproterenol; Leukemia; Macrophages; Monocytes; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pulmonary Alveoli; Signal Transduction; Superoxides; Tretinoin; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1993 |
Cross-talk between m1 muscarinic acetylcholine and beta 2-adrenergic receptors. cAMP and the third intracellular loop of m1 muscarinic receptors confer heterologous regulation.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Bucladesine; Carbachol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Down-Regulation; Isoproterenol; Isoquinolines; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Phosphatidylinositols; Protein Kinase Inhibitors; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptors, Adrenergic, beta; Receptors, Muscarinic; Sequence Deletion; Transfection | 1993 |
Cyclic strain and forskolin differentially induce cAMP production in phenotypically diverse endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; GTP-Binding Proteins; Humans; In Vitro Techniques; Isoproterenol; Periodicity; Signal Transduction; Stress, Mechanical | 1993 |
Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current.
Topics: Acetylcholine; Animals; Calcium Channels; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Hot Temperature; In Vitro Techniques; Isoproterenol; Kinetics; Myocardium; Photolysis; Propranolol; Rana catesbeiana; Rana esculenta; Receptors, Adrenergic, beta; Sympathetic Nervous System | 1993 |
Inhibitory glutamate response on cyclic AMP formation in cultured astrocytes.
Topics: Adenylate Cyclase Toxin; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; Iodine Radioisotopes; Isoproterenol; Pertussis Toxin; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Virulence Factors, Bordetella | 1993 |
Beta-adrenergic inhibition of electrical and mechanical activity in canine colon: role of cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Bacterial Toxins; Calcium; Colforsin; Colon; Cyclic AMP; Dogs; Electric Stimulation; Female; Fura-2; Hemolysin Proteins; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Neurotoxins; Receptors, Adrenergic, beta; Spectrometry, Fluorescence; Tetrodotoxin; Time Factors | 1993 |
Estradiol up-regulates the stimulatory GTP-binding protein expression in the MCF-7 human mammary carcinoma cell line.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Estradiol; GTP-Binding Proteins; Humans; Isoproterenol; Pertussis Toxin; Tumor Cells, Cultured; Up-Regulation; Virulence Factors, Bordetella | 1993 |
Recovery of beta-receptors and adenylate cyclase from desensitization induced by short term heat exposure in rat parotid glands.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Body Water; Colforsin; Down-Regulation; Epinephrine; GTP-Binding Proteins; Guanosine Diphosphate; Hot Temperature; In Vitro Techniques; Isoproterenol; Magnesium Chloride; Male; Membranes; Norepinephrine; Parotid Gland; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1993 |
Tumor necrosis factor produces homologous desensitization of lymphocyte beta 2-adrenergic responses.
Topics: Alprostadil; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Receptors, Adrenergic, beta; Shock, Septic; Tumor Necrosis Factor-alpha | 1993 |
Enhancement of the responsiveness of cortical adrenergic receptors by chronic administration of the 5-hydroxytryptamine uptake inhibitor citalopram.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Captopril; Cerebral Cortex; Citalopram; Colforsin; Cyclic AMP; Down-Regulation; Drug Administration Schedule; In Vitro Techniques; Isoproterenol; Kinetics; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Tetradecanoylphorbol Acetate | 1993 |
Reduced sensitivity of lymphocyte beta-adrenergic receptors in migraine.
Topics: Adult; Colforsin; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Migraine Disorders; Receptors, Adrenergic, beta | 1993 |
Effects of corticosteroids in preterm sheep on adaptation and sympathoadrenal mechanisms at birth.
Topics: Acclimatization; Adenylyl Cyclases; Adrenal Glands; Animals; Animals, Newborn; Blood Glucose; Blood Pressure; Body Weight; Cardiac Output; Colforsin; Cyclic AMP; Epinephrine; Fatty Acids, Nonesterified; Female; Fetus; Gestational Age; Hydrocortisone; Isoproterenol; Norepinephrine; Organ Size; Pregnancy; Reference Values; Regression Analysis; Respiration; Sheep; Sympathetic Nervous System | 1993 |
Cardiac beta-adrenoceptors, G-proteins and adenylate cyclase regulation during myocardial hypertrophy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Cardiomegaly; Cholera Toxin; Colforsin; Disease Models, Animal; Enzyme Activation; GTP-Binding Proteins; Isoproterenol; Myocardium; Pertussis Toxin; Receptors, Adrenergic, beta; Swine; Swine, Miniature; Virulence Factors, Bordetella | 1993 |
The effects of elevated cyclic AMP levels on histamine-H1-receptor-stimulated inositol phospholipid hydrolysis and calcium mobilization in the smooth-muscle cell line DDT1MF-2.
Topics: Animals; Calcium; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Hydrolysis; Inositol Phosphates; Isoproterenol; Male; Muscle, Smooth; Phosphatidylinositols; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Adrenergic, beta; Receptors, Histamine H1; Rolipram | 1993 |
Sensitization decreases relaxation in human isolated airways.
Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relationship, Drug; Humans; Immunization, Passive; Immunoglobulin E; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle Tonus; Parasympatholytics; Pyrroles; Verapamil | 1993 |
Protein kinase A activators inhibit agonist induced prostaglandin production in human amnion.
Topics: Adenylyl Cyclases; Amnion; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Female; Fetus; Humans; In Vitro Techniques; Isoproterenol; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Impaired beta-adrenergic receptor activation of adenylyl cyclase in airway smooth muscle in the basenji-greyhound dog model of airway hyperresponsiveness.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bucladesine; Cholera Toxin; Colforsin; Dinoprostone; Disease Models, Animal; Dogs; Enzyme Activation; Immunoblotting; Isoproterenol; Lung; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Radioimmunoassay; Receptors, Adrenergic, beta; Trachea | 1993 |
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Comparison of adenosine and muscarinic receptor-mediated effects on protein phosphatase inhibitor-1 activity in the heart.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carrier Proteins; Colforsin; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Phosphoprotein Phosphatases; Protein Kinases; Proteins; Receptors, Muscarinic; Receptors, Purinergic; Stimulation, Chemical; Ventricular Function; Xanthines | 1993 |
Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Glucagon; GTP-Binding Proteins; Isoproterenol; Lipolysis; Male; Rats; Rats, Wistar; Signal Transduction | 1993 |
Cyclic AMP mediated gene expression in bovine corneal endothelial cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Electrophoresis, Polyacrylamide Gel; Endothelium, Corneal; Gene Expression Regulation, Enzymologic; Isoproterenol; Transfection | 1993 |
Long-term inhibitory effect of cAMP on beta-adrenoceptor acquisition and nonselective attenuation of adenylyl cyclase in hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Down-Regulation; Glucagon; Iodocyanopindolol; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thionucleotides | 1993 |
Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Growth Hormone; Imidazoles; Insulin; Isoproterenol; Lipase; Lipolysis; Male; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Thyrotropin | 1993 |
Diltiazem prevents the depression of adenylyl cyclase activity induced by the calcium paradox in rat.
Topics: Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Diltiazem; Enzyme Activation; Isoproterenol; Male; Myocardium; Perfusion; Rats; Receptors, Adrenergic, beta; Sodium Fluoride | 1993 |
Cardioprotective properties of O-(beta-hydroxyethyl)-rutosides in doxorubicin-pretreated BALB/c mice.
Topics: Animals; Body Weight; Colforsin; Doxorubicin; Drug Administration Schedule; Free Radical Scavengers; Heart; Heart Rate; Hydroxyethylrutoside; Injections, Intraperitoneal; Injections, Intravenous; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocardium; Razoxane; Time Factors | 1993 |
Modulation of the ATP induced [Ca2+]c increase in AS-30D hepatoma cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Isoproterenol; Liver Neoplasms, Experimental; Phorbol Esters; Rats; Rats, Wistar; Tumor Cells, Cultured | 1993 |
Whole cell K and Cl currents in dissociated eccrine secretory coil cells during stimulation.
Topics: Animals; Barium; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Eccrine Glands; Electric Stimulation; Ionomycin; Isoproterenol; Macaca mulatta; Membrane Potentials; Methacholine Chloride; Models, Biological; Potassium Channels; Quinidine; Sodium; Time Factors | 1993 |
Opposing influences of dexamethasone and retinoic acid on adenylate cyclase activity in ROS 17/2.8 cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acid Sequence; Blotting, Northern; Cell Membrane; Colforsin; Dexamethasone; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoproterenol; Molecular Sequence Data; Osteosarcoma; RNA, Messenger; Sodium Fluoride; Tretinoin; Tumor Cells, Cultured | 1993 |
Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Cerebellum; Colforsin; Corticotropin-Releasing Hormone; Ethanol; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Mice; Mice, Mutant Strains; Pertussis Toxin; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Interaction of vanadate and iodate oxyanions with adenylyl cyclase of ciliary processes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Ciliary Body; Colforsin; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; In Vitro Techniques; Iodates; Isoproterenol; Kinetics; Magnesium; Rabbits; Vanadates; Vasoactive Intestinal Peptide | 1993 |
Topical norepinephrine, isoproterenol, terbutaline, forskolin and 8-bromo cyclic AMP increase lens equatorial current.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Topical; Animals; Colforsin; Electric Conductivity; In Vitro Techniques; Isoproterenol; Lens, Crystalline; Norepinephrine; Rana pipiens; Terbutaline; Timolol | 1993 |
Inhibitory effects of dopamine on noradrenaline-induced constriction of arterioles in vivo in the striated cremaster muscle.
Topics: Abdominal Muscles; Animals; Arterioles; Colforsin; Dopamine; Isoproterenol; Male; Norepinephrine; Rats; Rats, Wistar; Vasoconstriction; Vasopressins | 1993 |
Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one.
Topics: Adenosine Diphosphate; Anesthesia; Animals; Cardiotonic Agents; Cats; Colforsin; Cricetinae; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Heart Failure; Ileum; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Male; Mesocricetus; Muscle, Smooth; Myocardial Reperfusion Injury; Papillary Muscles; Platelet Aggregation; Propranolol; Rats; Rats, Wistar; Regional Blood Flow | 1993 |
Vasoactive intestinal peptide stimulates type II thyroxine 5'-deiodinase and N-acetyltransferase activities in dispersed pineal cells of euthyroid and hypothyroid rats.
Topics: Animals; Arylamine N-Acetyltransferase; Colforsin; Hypothyroidism; In Vitro Techniques; Iodide Peroxidase; Iodine Radioisotopes; Isoproterenol; Pineal Gland; Propranolol; Rats; Vasoactive Intestinal Peptide | 1993 |
Regulation of adenylate cyclase in plasma membranes of human intraabdominal and abdominal subcutaneous adipocytes.
Topics: Abdomen; Adenylyl Cyclases; Adipose Tissue; Analysis of Variance; Cell Membrane; Colforsin; Diterpenes; Enzyme Activation; Humans; Isoproterenol; Mesentery; Middle Aged; Omentum; Phenylisopropyladenosine; Skin | 1993 |
Agonist-induced effects on cyclic AMP metabolism are affected in pigment epithelial cells of the Royal College of Surgeons rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Fibroblast Growth Factor 2; Imidazoles; Isoproterenol; Kinetics; Melatonin; Pigment Epithelium of Eye; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta-2; Receptors, Purinergic P1; Serotonin | 1995 |
Effect of essential fatty acid deficiency on forskolin binding sites, adenylate cyclase and cyclic AMP-dependent protein kinase activity, the levels of G proteins and ventricular function in rat heart.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Cell Membrane; Cholesterol; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fatty Acids, Essential; GTP-Binding Proteins; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Membrane Lipids; Myocardium; Phospholipids; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Reference Values; Signal Transduction; Ventricular Function, Left | 1995 |
Effectors of cyclic adenosine 5'-monophosphate up-regulating-oxytocin receptors in rabbit amnion cells: isoproterenol, parathyroid hormone-related protein, and potentiation by cortisol.
Topics: Adenylyl Cyclases; Amnion; Animals; Colforsin; Cyclic AMP; DNA; Drug Synergism; Female; Gonanes; Hormone Antagonists; Hydrocortisone; Isoproterenol; Mifepristone; Parathyroid Hormone-Related Protein; Pregnancy; Proteins; Rabbits; Receptors, Glucocorticoid; Receptors, Oxytocin | 1995 |
A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.
Topics: Animals; Colforsin; Conditioning, Psychological; Cyclic AMP-Dependent Protein Kinase RIbeta Subunit; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Female; Hippocampus; Isoenzymes; Isoproterenol; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Spatial Behavior | 1995 |
cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels; Cell Compartmentation; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Ion Channel Gating; Isoproterenol; Rana esculenta; Signal Transduction | 1996 |
Endothelins inhibit cyclic AMP production in rabbit and human ciliary processes.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Animals; Aqueous Humor; Ciliary Body; Colforsin; Cyclic AMP; Endothelins; Humans; Isoproterenol; Male; Rabbits; Receptors, Endothelin; Vasoactive Intestinal Peptide | 1995 |
Norepinephrine-induced phosphorylation of the transcription factor CREB in isolated rat pinealocytes: an immunocytochemical study.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Antibody Specificity; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; Immunohistochemistry; Isoproterenol; Male; Norepinephrine; Phenylephrine; Phosphorylation; Pineal Gland; Rats; Rats, Wistar; Transcription Factors | 1995 |
Burn injury alters beta-adrenergic receptor and second messenger function in rat ventricular muscle.
Topics: Adrenergic beta-Agonists; Animals; Burns; Cell Membrane; Colforsin; Cyclic AMP; Heart Ventricles; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Male; Myocardium; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Second Messenger Systems; Signal Transduction | 1996 |
Antagonism of beta-adrenergic stimulation of L-type Ca2+ current by endothelin in guinea-pig atrial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium Channels; Colforsin; Cyclic AMP; Electric Stimulation; Endothelins; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardium | 1995 |
Impaired regulation of cell communication by beta-adrenergic receptor activation in the failing heart.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiomyopathies; Cell Communication; Colforsin; Cricetinae; Electric Conductivity; Gap Junctions; Heart; Heart Failure; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Mesocricetus; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Adrenergic, beta; Reference Values | 1996 |
Adrenergic desensitization in left ventricle from streptozotocin diabetic swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aluminum; Animals; Blood Glucose; Colforsin; Cyclic AMP; Cytosol; Diabetes Mellitus, Experimental; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; Insulin; Isoproterenol; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Streptozocin; Swine; Swine, Miniature | 1995 |
Chloride conductance in human atrial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Atrial Function; Child; Child, Preschool; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Heart; Heart Atria; Humans; Hypotonic Solutions; Infant; Ion Channel Gating; Isoproterenol; Membrane Potentials; Middle Aged; Myocardium; Osmotic Pressure; Patch-Clamp Techniques | 1995 |
Cholera toxin accentuates the antagonism by acetylcholine of higenamine-induced positive chronotropy is isolated right atria of mice.
Topics: Acetylcholine; Alkaloids; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Dobutamine; Drug Synergism; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred Strains; Pertussis Toxin; Stimulation, Chemical; Tetrahydroisoquinolines; Virulence Factors, Bordetella | 1995 |
Rat thymic epithelial cells in vitro and in situ: characterization by immunocytochemistry and morphology.
Topics: Animals; Biomarkers; Cattle; Cell Culture Techniques; Cell Division; Cells, Cultured; Colforsin; Culture Media; Epithelial Cells; Epithelium; Female; Fetal Blood; Hydrocortisone; Isoproterenol; Keratins; Microscopy, Electron; Organelles; Rats; Rats, Wistar; Thymic Factor, Circulating; Thymus Gland | 1996 |
Regulation and bioelectrical effects of cyclic adenosine monophosphate production in the ciliary epithelial bilayer.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Ciliary Body; Clonidine; Colforsin; Cyclic AMP; Electrophysiology; Isoproterenol; Male; Membrane Potentials; Pigment Epithelium of Eye; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Timolol; Vasoactive Intestinal Peptide | 1996 |
Endothelin-1 inhibits L-type Ca currents enhanced by isoproterenol in guinea-pig ventricular myocytes.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Endothelins; Guinea Pigs; Heart Ventricles; Histamine; Isoproterenol; Membrane Potentials; Myocardium; Receptors, Endothelin | 1996 |
Involvement of the M2 muscarinic receptor in contractions of the guinea pig trachea, guinea pig esophagus, and rat fundus.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Esophagus; Gastric Fundus; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Trachea; Virulence Factors, Bordetella | 1996 |
Inhibition of cyclic AMP accumulation by endothelin is pertussis toxin sensitive and calcium independent in isolated adult feline cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Calcium; Cardiotonic Agents; Cats; Cells, Cultured; Colforsin; Cyclic AMP; Endothelins; GTP-Binding Proteins; Heart; Isoproterenol; Myocardium; Pertussis Toxin; Phosphodiesterase Inhibitors; Sensitivity and Specificity; Virulence Factors, Bordetella | 1996 |
Inhibition of muscarinic stimulated phosphoinositide hydrolysis in the rat parotid gland by cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Drug Interactions; Hydrolysis; Isoproterenol; Male; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Parotid Gland; Phosphatidylinositols; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sodium Fluoride; Stimulation, Chemical | 1996 |
Effect of cesarean delivery on perioperative regulation of the beta-adrenergic receptor system of human lymphocytes.
Topics: Abdomen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Alprostadil; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Colforsin; Cyclic AMP; Down-Regulation; Female; Humans; Iodine Radioisotopes; Isoproterenol; Lymphocytes; Pindolol; Pregnancy; Receptors, Adrenergic, beta; Stress, Physiological; Thoracic Surgery; Vasodilator Agents | 1996 |
Role of altered beta-adrenoceptor signal transduction in the pathogenesis of cirrhotic cardiomyopathy in rats.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Cardiomyopathies; Cell Membrane; Colforsin; Cyclic AMP; GTP-Binding Proteins; Isoproterenol; Liver Cirrhosis, Experimental; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride | 1996 |
Adrenergic modulation of ultrarapid delayed rectifier K+ current in human atrial myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Atrial Function; Colforsin; Electric Conductivity; Heart Atria; Humans; Indoles; Isoproterenol; Maleimides; Myocardium; Phenylephrine; Potassium Channels; Protein Kinase C; Receptors, Adrenergic; Time Factors | 1996 |
Nitric oxide synthase (NOS3) and contractile responsiveness to adrenergic and cholinergic agonists in the heart. Regulation of NOS3 transcription in vitro and in vivo by cyclic adenosine monophosphate in rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Heart; Isoproterenol; Kinetics; Male; Milrinone; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1996 |
Frequency modulation of acetylcholine-induced oscillations in Ca++ and Ca(++)-activated Cl- current by cAMP in tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Potassium Channels; Swine; Trachea | 1996 |
A G protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Endothelium, Vascular; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoproterenol; Norepinephrine; Pertussis Toxin; Potassium Channels; Thionucleotides; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1996 |
The biological activity of the corticotropin-releasing hormone receptor-adenylate cyclase complex in human myometrium is reduced at the end of pregnancy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Membrane; Cholera Toxin; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Female; Humans; Isoproterenol; Myometrium; Pertussis Toxin; Pregnancy; Pregnancy Trimester, Third; Receptors, Corticotropin-Releasing Hormone; Virulence Factors, Bordetella | 1996 |
Chronic treatment with carbachol sensitizes the myocardium to cAMP-induced arrhythmia.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Carbachol; Colforsin; Cyclic AMP; GTP-Binding Proteins; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Muscarinic; RNA, Messenger; Virulence Factors, Bordetella | 1996 |
Regulation of cardiac sodium-calcium exchanger by beta-adrenergic agonists.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Colforsin; Cyclic AMP; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Myocardial Contraction; Nickel; Patch-Clamp Techniques; Propranolol; Rana pipiens; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Theophylline | 1996 |
Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation.
Topics: Adenylyl Cyclases; Animals; Antibodies; Carbachol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Muscarinic Agonists; Phosphoric Diester Hydrolases; Receptors, Muscarinic; Recombinant Proteins; Transfection | 1996 |
Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Cell Membrane; Colforsin; Cytokines; Diamines; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Proteins; In Vitro Techniques; Interleukin-1; Interleukin-2; Isometric Contraction; Isoproterenol; Kinetics; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Pertussis Toxin; Rabbits; Receptors, Adrenergic, beta; Signal Transduction; Trachea; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1996 |
Specific potentiation by cyclic AMP of natriuretic peptide-mediated cyclic GMP production in adipose tissue.
Topics: 3T3 Cells; Adipose Tissue; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic GMP; Isoproterenol; Mice; Natriuretic Peptide, C-Type; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 1996 |
beta-Adrenergic relaxation in mesenteric resistance arteries of spontaneously hypertensive and Wistar-Kyoto rats: the role of precontraction and intracellular Ca2+.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vascular Resistance | 1996 |
Human astrocytoma U138MG cells express predominantly type-A endothelin receptor.
Topics: Astrocytoma; Base Sequence; Binding, Competitive; Cell Membrane; Colforsin; Cyclic AMP; DNA Primers; Endocytosis; Endothelin Receptor Antagonists; Endothelins; Guanylyl Imidodiphosphate; Histamine; Humans; Isoproterenol; Ligands; Molecular Sequence Data; Phosphatidylinositols; Polymerase Chain Reaction; Protein Binding; Pyrimidines; Receptor, Endothelin A; Receptors, Endothelin; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured | 1996 |
beta-Adrenergic modulation of the inwardly rectifying potassium channel in isolated human ventricular myocytes. Alteration in channel response to beta-adrenergic stimulation in failing human hearts.
Topics: Adrenergic beta-Agonists; Adult; Alkaline Phosphatase; Analysis of Variance; Barium; Bucladesine; Cardiomyopathy, Dilated; Cells, Cultured; Colforsin; Coronary Disease; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Heart; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Kinetics; Male; Membrane Potentials; Middle Aged; Myocardium; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Propranolol | 1995 |
Opposite regulation by the beta-adrenoceptor-cyclic AMP system of synaptic plasticity in the medial and lateral amygdala in vitro.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amygdala; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Neuronal Plasticity; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Synapses; Synaptic Transmission; Timolol | 1996 |
Rapid regulation of a cyclic AMP-specific phosphodiesterase (PDE IV) by forskolin and isoproterenol in LRM55 astroglial cells.
Topics: Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Isoproterenol; Phosphoric Diester Hydrolases; Rats; Time Factors | 1996 |
Beta-adrenergic signalling in neoplastic lung type 2 cells: glucocorticoid-dependent and -independent defects.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Dexamethasone; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Lung Neoplasms; Mice; Pindolol; Receptors, Adrenergic, beta | 1996 |
Inducible expression of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells: functional interactions between closely related subtypes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Cyclic AMP; Epinephrine; Gene Expression Regulation, Neoplastic; Genomic Library; Glioma; Imidazoles; Isopropyl Thiogalactoside; Isoproterenol; Kinetics; Norepinephrine; Pindolol; Radioligand Assay; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1996 |
beta-Adrenoceptor activates endothelium-dependent release of nitric oxide in rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Arginine; Colforsin; Endothelium, Vascular; Female; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Triiodothyronine regulates beta 3-adrenoceptor expression in 3T3-F442A differentiating adipocytes.
Topics: 3T3 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Antagonists; Animals; Base Sequence; Cell Differentiation; Cell Nucleus; Colforsin; Dactinomycin; DNA Primers; Gene Expression; Glycerolphosphate Dehydrogenase; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Kinetics; Mice; Molecular Sequence Data; Propanolamines; Protein Biosynthesis; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triiodothyronine | 1996 |
Developmental changes in beta-adrenergic and muscarinic modulations of Ca2+ currents in fetal and neonatal ventricular cardiomyocytes of the rat.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Calcium Channels; Carbachol; Cell Size; Colforsin; Embryonic and Fetal Development; Heart Ventricles; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Patch-Clamp Techniques; Rats; Stimulation, Chemical | 1996 |
Altered pharmacologic responsiveness of reduced L-type calcium currents in myocytes surviving in the infarcted heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Colforsin; Cyclic AMP; Dogs; Heart; Isoproterenol; Myocardial Infarction | 1996 |
Impairment of adenylyl cyclase signal transduction in mecobalamin-deficient rats.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cerebral Cortex; Colforsin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Vitamin B 12 | 1995 |
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colforsin; Cyclic AMP; Heart Ventricles; Isoproterenol; Male; Molecular Sequence Data; Rabbits; Stimulation, Chemical; Therapeutic Equivalency | 1996 |
Expression of functional muscarinic acetylcholine receptor subtypes in human corpus cavernosum and in cultured smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Atropine; Carbachol; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Humans; In Situ Hybridization; Isoproterenol; Kinetics; Male; Models, Biological; Muscle, Smooth; Penis; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic | 1995 |
Paradoxical facilitation of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by isoprenaline.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Atropine; Colforsin; Cyclic AMP; Dinoprostone; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Neuromuscular Junction; Parasympathetic Nervous System; Phosphodiesterase Inhibitors; Synaptic Transmission; Trachea | 1996 |
Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum.
Topics: 2-Chloroadenosine; Animals; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Inhibition of T cell cAMP formation by cyclosporin A and FK506.
Topics: Adult; Aged; Colforsin; Cyclic AMP; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Isoproterenol; Male; Middle Aged; Psoriasis; T-Lymphocytes; Tacrolimus | 1996 |
Changes in autonomic response of the cerebral circulation after normothermic extracorporeal circulation.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Blood Circulation; Blood Pressure; Cardiopulmonary Bypass; Carotid Artery, Internal; Cerebral Arteries; Cerebrovascular Circulation; Cholinergic Agonists; Colforsin; Enzyme Activation; Extracorporeal Circulation; Female; Guanylate Cyclase; Injections, Intra-Arterial; Isoproterenol; Male; Microcirculation; Nitroprusside; Second Messenger Systems; Swine; Vascular Resistance; Vasodilator Agents | 1996 |
Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein.
Topics: Amyloid beta-Protein Precursor; Animals; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Phorbol Esters; Protein Processing, Post-Translational; Rats; Signal Transduction | 1996 |
Diurnal and seasonal changes in sympathetic signal transduction in cardiac ventricles of European hamsters.
Topics: Adenylyl Cyclases; Animals; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Guanylyl Imidodiphosphate; Heart Conduction System; Hibernation; Isoproterenol; Receptors, Adrenergic, beta; Seasons; Signal Transduction; Sympathetic Nervous System | 1996 |
Dissociation of negative inotropic effect of carbachol from changes in cAMP and PKA in perfused rat hearts.
Topics: Alprostadil; Animals; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Isoproterenol; Male; Muscarinic Agonists; Myocardial Contraction; Myocardium; Perfusion; Pressure; Rats; Rats, Wistar; Ventricular Function, Left | 1996 |
Abolition of spindle oscillations by serotonin and norepinephrine in the ferret lateral geniculate and perigeniculate nuclei in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cesium; Colforsin; Electrophysiology; Female; Ferrets; Geniculate Bodies; Isoproterenol; Male; Norepinephrine; Periodicity; Serotonin | 1996 |
Evidence for pharmacologically distinct GABAB receptors associated with cAMP production in rat brain.
Topics: Adrenergic beta-Agonists; Animals; Brain Chemistry; Cerebral Cortex; Colforsin; Cyclic AMP; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Signal Transduction | 1996 |
Inhibition of microglial superoxide anion production by isoproterenol and dexamethasone.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Cytochrome c Group; Depression, Chemical; Dexamethasone; Isoproterenol; Microglia; Propranolol; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Selective enhancement by serum factors of cyclic AMP accumulation in rat microglial cultures.
Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Blood Physiological Phenomena; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Dinoprostone; Isoproterenol; Microglia; Rats; Rats, Wistar; Stimulation, Chemical | 1996 |
Acetylcholine inhibits Ca2+ current by acting exclusively at a site proximal to adenylyl cyclase in frog cardiac myocytes.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Isoproterenol; Micromanipulation; Myocardium; Patch-Clamp Techniques; Perfusion; Rana esculenta | 1996 |
Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin.
Topics: Adipocytes; Amiloride; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diffusion; Fatty Acids, Nonesterified; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Models, Biological; Norepinephrine; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sodium; Time Factors | 1996 |
Modulation of agonist-induced phosphoinositide metabolism, Ca2+ signalling and contraction of airway smooth muscle by cyclic AMP-dependent mechanisms.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Cattle; Cells, Cultured; Cholinergic Agents; Colforsin; Cyclic AMP; Histamine; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Signal Transduction; Trachea | 1996 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isoproterenol; Lysophospholipids; Neuroglia; Pertussis Toxin; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Potent inhibition of spontaneous rhythmic contraction by a novel beta 2-adrenoceptor agonist, HSR-81, in pregnant rat uterus.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzyl Alcohols; Binding, Competitive; Colforsin; Diestrus; Female; Gestational Age; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Isotope Labeling; Kinetics; Pindolol; Pregnancy; Propanolamines; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Ritodrine; Uterine Contraction | 1996 |
Inhibition of cAMP-mediated relaxation of rabbit tracheal smooth muscle by neuropeptide Y.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP; Isometric Contraction; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Neuropeptide Y; Rabbits; Trachea | 1996 |
Effect of endurance physical training on rat liver adenylyl cyclase system.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Colforsin; Enzyme Activation; Fluorides; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Manganese; Physical Conditioning, Animal; Physical Endurance; Pindolol; Random Allocation; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1996 |
Modulation of Ca2+ current in canine colonic myocytes by cyclic nucleotide-dependent mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Colon; Cyclic AMP; Dogs; Ion Transport; Isoproterenol; Muscle, Smooth; Patch-Clamp Techniques; Vasoactive Intestinal Peptide | 1996 |
Serum modulates cyclic AMP-dependent morphological changes in cultured neurohypophysial astrocytes.
Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Cells, Cultured; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Glial Fibrillary Acidic Protein; Immunohistochemistry; Isoproterenol; Male; Neuronal Plasticity; Pituitary Gland, Posterior; Rats; Rats, Sprague-Dawley | 1996 |
Altered beta-adrenergic and cholinergic pulmonary vascular responses after total cardiopulmonary bypass.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Cardiopulmonary Bypass; Cholinergic Fibers; Colforsin; Dose-Response Relationship, Drug; Isoproterenol; Pulmonary Circulation; Sheep; Time Factors | 1995 |
Regulation of lipolysis in fat cells of obese women during long-term hypocaloric diet.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Brimonidine Tartrate; Bucladesine; Catecholamines; Colforsin; Dobutamine; Energy Intake; Female; Food Deprivation; Glucose; Humans; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Middle Aged; Obesity; Propanolamines; Quinoxalines; Terbutaline; Time Factors | 1996 |
Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives.
Topics: Adipocytes; Adrenergic beta-Agonists; Adult; Body Mass Index; Bucladesine; Clonidine; Colforsin; Diabetes Mellitus, Type 2; Dobutamine; Dose-Response Relationship, Drug; Female; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Norepinephrine; Nuclear Family; Obesity; Pedigree; Receptors, Adrenergic, beta; RNA, Messenger; Sterol Esterase; Sympathomimetics; Terbutaline | 1996 |
Evaluation of cyclic AMP accumulation in EBV-transformed human B-lymphocytes: effects of dopamine agonists, isoproterenol, prostaglandin E1, cholera toxin, forskolin, and phorbol 12-myristate-13 acetate.
Topics: Alprostadil; B-Lymphocytes; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Isoproterenol; Phorbol Esters | 1996 |
Sensitization of endogenous and recombinant adenylate cyclase by activation of D2 dopamine receptors.
Topics: Adenylyl Cyclases; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Isoenzymes; Isoproterenol; Kinetics; Receptors, Dopamine D2; Recombinant Proteins; Second Messenger Systems; Sensitivity and Specificity; Spiperone; Stimulation, Chemical; Tetrahydronaphthalenes | 1996 |
Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Down Syndrome; Female; Hippocampus; Isoproterenol; Mice; Phosphodiesterase Inhibitors | 1996 |
Blockade of isoproterenol-induced synaptic potentiation by tetra-9-aminoacridine in the rat amygdala.
Topics: Adrenergic beta-Agonists; Amygdala; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Membrane Potentials; Neuronal Plasticity; Parasympathomimetics; Rats; Synapses; Synaptic Membranes; Synaptic Transmission; Tacrine | 1996 |
Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.
Topics: Animals; Autoradiography; Bronchi; Colforsin; Cyclic AMP; GTP-Binding Proteins; Interleukin-1; Isoproterenol; Muscle Relaxation; Rats; Rats, Inbred BN; Receptors, Adrenergic, beta; RNA, Messenger; Trachea | 1996 |
Beta-adrenoceptor desensitization despite cardiac denervation in human failing transplanted myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Biopsy; Colforsin; Denervation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Transplantation; Heart Ventricles; Humans; Isoproterenol; Ventricular Function, Left | 1996 |
Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
Topics: Adrenergic beta-Agonists; Allopurinol; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Vasodilator Agents | 1996 |
Modulation of interleukin-1 receptors in the brain-endocrine-immune axis by stress and infection.
Topics: Anesthetics, Inhalation; Animals; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Endotoxins; Ether; Gene Expression Regulation; Hippocampus; Humans; Infections; Interleukin-1; Isoproterenol; Laparotomy; Liver; Male; Mice; Mice, Inbred C57BL; Neuroimmunomodulation; Pituitary Gland; Pituitary Neoplasms; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Interleukin-1; Recombinant Proteins; Somatostatin; Spleen; Stress, Physiological; Testis; Tumor Cells, Cultured | 1995 |
Potentiation of acetylcholine release from tracheal parasympathetic nerves by cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP; Electric Stimulation; Horses; In Vitro Techniques; Isoproterenol; Parasympathetic Nervous System; Trachea | 1996 |
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Colforsin; Dose-Response Relationship, Drug; Hyperthyroidism; Imidazoles; Isoproterenol; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle Relaxation; Propanolamines; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Thromboxane A2; Thyroxine; Vascular Resistance; Vasoconstrictor Agents | 1996 |
cAMP-dependent facilitation of glutamate release by beta-adrenergic receptors in cerebrocortical nerve terminals.
Topics: Animals; Arachidonic Acid; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Isoproterenol; Membrane Potentials; Nerve Endings; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sodium Channel Blockers; Synaptosomes; Tetrodotoxin; Time Factors | 1996 |
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Actins; Bradykinin; Bronchodilator Agents; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Collagen; Cytoskeleton; Dinoprostone; Histamine; Humans; Isoproterenol; Kinetics; Magnetics; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Myosins; Potassium Chloride; Substance P; Time Factors; Trachea | 1996 |
Influence of cardiac dysfunction on fast sodium current regulation by Forskolin.
Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Colforsin; Diastole; Down-Regulation; Isoproterenol; Male; Myocardial Infarction; Myocardium; Papillary Muscles; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sodium; Sodium Channels; Ventricular Function, Left; Ventricular Pressure | 1996 |
Signal-transduction-pathway-specific desensitization of expression of orphan nuclear receptor TIS1.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; DNA-Binding Proteins; Gene Expression Regulation; Isoproterenol; Mice; Muscle, Skeletal; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Cyclic AMP-induced desensitization of G-protein-regulated phospholipase C in turkey erythrocyte membranes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Drug Interactions; Erythrocytes; GTP-Binding Proteins; Isoproterenol; Phosphodiesterase Inhibitors; Sympathomimetics; Turkeys; Type C Phospholipases | 1996 |
Studies on pyrazinoylguanidine. 3. Downregulation of lipolysis in isolated adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Down-Regulation; Glycerol; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Isoproterenol; Lipase; Lipolysis; Male; Pertussis Toxin; Pyrazines; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1996 |
Interleukin-1 beta increases prostaglandin E2-stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Interleukin-1; Isoproterenol; Kinetics; Lipopolysaccharides; Pigment Epithelium of Eye; Protein Synthesis Inhibitors; Rabbits; Stimulation, Chemical; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation; Vasoactive Intestinal Peptide | 1996 |
The vasorelaxant effects of amrinone on neonatal rabbit thoracic aortic strips.
Topics: Adrenergic beta-Antagonists; Amrinone; Animals; Animals, Newborn; Aorta, Thoracic; Colforsin; Culture Techniques; Female; Isoproterenol; Male; Phosphodiesterase Inhibitors; Rabbits; Theophylline; Vasodilator Agents | 1996 |
Effects of age on beta adrenergic subtype activation of adenylyl cyclase in brown adipose tissue.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Adrenergic beta-Agonists; Age Factors; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Ethanolamines; Gene Expression; Glucagon; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3; Regression Analysis; RNA, Messenger; Sodium Fluoride | 1996 |
[Chronotropic effects of alpha-agonist on the rat isolated right atria].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Colforsin; Depression, Chemical; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1996 |
Cocaine and beta-adrenergic receptor function in pregnant myometrium.
Topics: Cocaine; Colforsin; Cyclic AMP; Female; Humans; In Vitro Techniques; Isoproterenol; Myometrium; Osmolar Concentration; Pregnancy; Receptors, Adrenergic, beta; Sodium Fluoride | 1996 |
Effects of blood and crystalloid cardioplegia on adrenergic and myogenic vascular mechanisms.
Topics: Animals; Blood; Cardioplegic Solutions; Clonidine; Colforsin; Coronary Circulation; Coronary Vessels; Female; Heart Arrest, Induced; Isoproterenol; Male; Myocardial Contraction; Nitroprusside; Potassium Compounds; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Swine | 1997 |
Effect of HDL and atherogenic lipoproteins on formation of O2- and renin release in juxtaglomerular cells.
Topics: Adrenergic beta-Agonists; Animals; Arteriosclerosis; Cell-Free System; Cells, Cultured; Cholesterol, HDL; Cholesterol, LDL; Colforsin; Humans; Isoproterenol; Juxtaglomerular Apparatus; Lipoprotein(a); Melitten; Mice; Oxidation-Reduction; Rats; Reactive Oxygen Species; Renin | 1997 |
Differences in isoproterenol stimulation of Ca2+ current of rat ventricular myocytes in neonatal compared to adult.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Calcium Channel Agonists; Calcium Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 1996 |
Endothelin-1 inhibits L-type Ca2+ current enhanced by isoprenaline in rat atrial myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Heart Atria; Isoproterenol; Myocardium; Patch-Clamp Techniques; Protein Kinase Inhibitors; Rats | 1997 |
Contribution of ATP-sensitive potassium channels to beta-adrenoceptor-mediated responses.
Topics: Adenosine Triphosphate; Animals; Bisoprolol; Colforsin; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasoconstriction | 1997 |
Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antibodies, Blocking; Asthma; Blotting, Northern; Cells, Cultured; Colforsin; Culture Techniques; Dinoprostone; Humans; Immunization, Passive; Interleukin-1; Isoproterenol; Muscle, Smooth; Polymerase Chain Reaction; Rabbits; Radioimmunoassay; Rats; Receptors, Interleukin-1; RNA, Messenger; Trachea | 1997 |
Isoproterenol decreases LDL receptor expression in rat adipose cells: activation of cyclic AMP-dependent proteolysis.
Topics: Adipocytes; Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Immunoblotting; Immunosorbent Techniques; Isoproterenol; Male; Molecular Sequence Data; Propranolol; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, LDL; Recombinant Fusion Proteins; RNA, Messenger | 1996 |
Zatebradine inhibits tachycardia induced by bronchodilators without affecting respiratory resistance in dogs.
Topics: Airway Resistance; Aminophylline; Animals; Benzazepines; Bronchodilator Agents; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Female; Heart Rate; Histamine; Isoproterenol; Male; Procaterol; Tachycardia | 1997 |
Defects of beta 2-adrenergic signal transduction in chronic lymphocytic leukaemia: relationship to disease progression.
Topics: Adult; Aged; Cholera Toxin; Colforsin; Cyclic AMP; Disease Progression; Female; Humans; Isoproterenol; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, Adrenergic, beta-2; Regression Analysis; Signal Transduction; Statistics, Nonparametric | 1997 |
Regulation of lipolysis by somatotropin: functional alteration of adrenergic and adenosine signaling in bovine adipose tissue.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Deaminase; Adipose Tissue; Adrenergic beta-Agonists; Animals; Bucladesine; Cattle; Colforsin; Culture Techniques; Dose-Response Relationship, Drug; Fasting; Female; Growth Hormone; GTP-Binding Proteins; Hypolipidemic Agents; Isoproterenol; Lactation; Lipolysis; Phenylisopropyladenosine; Signal Transduction | 1997 |
Regulation of thyrotropin receptor gene expression in 3T3-L1 adipose cells is distinct from its regulation in FRTL-5 thyroid cells.
Topics: 3T3 Cells; Adipose Tissue; Animals; Bucladesine; Colforsin; Down-Regulation; Gene Expression Regulation; Homeodomain Proteins; Isoproterenol; Mice; Nuclear Proteins; Promoter Regions, Genetic; Rats; Receptors, Thyrotropin; RNA, Messenger; Thyroid Gland; Thyroid Nuclear Factor 1; Transcription Factors | 1997 |
Modulation of dog atrial swelling-induced chloride current by cAMP: protein kinase A-dependent and -independent pathways.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carrier Proteins; Cells, Cultured; Chloride Channels; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Heart; Heart Atria; Humans; Intracellular Signaling Peptides and Proteins; Isoproterenol; KB Cells; Kinetics; Membrane Potentials; Peptide Fragments; Phosphorylation | 1997 |
Regulation of pineal alpha1B-adrenergic receptor mRNA: day/night rhythm and beta-adrenergic receptor/cyclic AMP control.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cholera Toxin; Circadian Rhythm; Colforsin; Cyclic AMP; Female; Isoproterenol; Male; Norepinephrine; Phenylephrine; Pineal Gland; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Messenger; Vasoactive Intestinal Peptide | 1997 |
Lipolytic catecholamine resistance linked to alpha 2-adrenoceptor sensitivity--a metabolic predictor of weight loss in obese subjects.
Topics: Adenosine Deaminase; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Biomarkers; Biopsy; Clonidine; Cohort Studies; Colforsin; Dobutamine; Dose-Response Relationship, Drug; Female; Glycerol; Humans; Isoproterenol; Lipolysis; Middle Aged; Norepinephrine; Obesity; Receptors, Adrenergic, alpha; Terbutaline; Time Factors; Weight Loss | 1997 |
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine | 1997 |
Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Chromosome Mapping; Chromosomes, Human, Pair 21; Colforsin; Cyclic AMP; Down Syndrome; Hippocampus; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Mice; Mice, Neurologic Mutants; Norepinephrine; Organ Specificity; Propanolamines; Receptors, Adrenergic, beta; Reference Values; Signal Transduction | 1997 |
Temporal effects of cytokines on neonatal cardiac myocyte Ca2+ transients and adenylate cyclase activity.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Guanosine Triphosphate; Heart; Heart Ventricles; Interleukin-1; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Rats; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Beta-adrenoceptor-linked signal transduction in ischemic-reperfused heart and scavenging of oxyradicals.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Catalase; Cell Membrane; Cholera Toxin; Colforsin; Free Radical Scavengers; GTP-Binding Proteins; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Myocardial Ischemia; Myocardial Reperfusion; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Adrenergic, beta; Signal Transduction; Superoxide Dismutase; Virulence Factors, Bordetella | 1997 |
The effect of age on adenosine A1 receptor function in the rat heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Carbachol; Cardiovascular Agents; Cell Membrane; Colforsin; Heart; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sulfonic Acids; Theophylline | 1997 |
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors | 1997 |
Electrophysiology of rabbit ventricular myocytes following sustained rapid ventricular pacing.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels; Cardiac Pacing, Artificial; Cells, Cultured; Colforsin; Electrophysiology; Heart Ventricles; Hemodynamics; Ion Channels; Isoproterenol; Male; Patch-Clamp Techniques; Potassium Channels; Rabbits; Ventricular Function | 1997 |
Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclosporine; Isoproterenol; Kinetics; Norepinephrine; Phosphatidylinositols; Propranolol; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1997 |
Two-dimensional millisecond analysis of intracellular Ca2+ sparks in cardiac myocytes by rapid scanning confocal microscopy: increase in amplitude by isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calmodulin-Binding Proteins; Cardiotonic Agents; Colforsin; Heart; Isoproterenol; Microscopy, Confocal; Muscle Proteins; Myocardium; Nicardipine; Propranolol; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors | 1997 |
Increased cyclic AMP response to forskolin in Epstein-Barr virus-transformed human B-lymphocytes derived from schizophrenics.
Topics: Adult; Alprostadil; B-Lymphocytes; Cell Transformation, Viral; Cholera Toxin; Colforsin; Cyclic AMP; Female; Herpesvirus 4, Human; Humans; Isoproterenol; Lymphocyte Activation; Male; Schizophrenia; Tetradecanoylphorbol Acetate | 1997 |
Decreased beta-adrenoceptor-stimulated adenylyl cyclase activity in lymphocytes from Alzheimer's disease patients.
Topics: Adenylyl Cyclases; Aged; Alzheimer Disease; Colforsin; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta | 1997 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotoxin; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Fenoterol; Glyburide; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Pyrroles; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Regulation of corticotropin-releasing factor receptor function in human Y-79 retinoblastoma cells: rapid and reversible homologous desensitization but prolonged recovery.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Blotting, Northern; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Isoproterenol; Membrane Proteins; Receptors, Corticotropin-Releasing Hormone; Retinoblastoma; RNA, Messenger; Sensitivity and Specificity; Time Factors; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1997 |
Down-regulation of 5-hydroxytryptamine7 receptors by dexamethasone in rat frontocortical astrocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Animals; Astrocytes; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Down-Regulation; Frontal Lobe; Gene Expression; Glucocorticoids; Isoproterenol; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Serotonin; RNA, Messenger; Serotonin; Vasodilator Agents | 1997 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
Role of nitric oxide in vasodilator response induced by salbutamol in rat diaphragmatic microcirculation.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Arginine; Blood Pressure; Colforsin; Diaphragm; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Isoproterenol; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilation | 1997 |
Potentiation of the relaxing action of isoproterenol by forskolin in rabbit aortic rings: the involvement of beta 2-adrenoceptors.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Bucladesine; Colforsin; Dobutamine; Drug Synergism; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Terbutaline | 1997 |
Effect of IL-1 beta on responses of cultured human airway smooth muscle cells to bronchodilator agonists.
Topics: Adenylyl Cyclases; Binding, Competitive; Blotting, Western; Bronchodilator Agents; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Fungal Proteins; GTP-Binding Proteins; Humans; Interleukin-1; Iodine Radioisotopes; Isoproterenol; Magnetics; Muscle, Smooth; Oxytocics; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cytokine; Saccharomyces cerevisiae Proteins; Trachea; Vesicular Transport Proteins | 1997 |
Genistein directly induces cardiac CFTR chloride current by a tyrosine kinase-independent and protein kinase A-independent pathway in guinea pig ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Ventricles; Isoflavones; Isoproterenol; Isoquinolines; Male; Marine Toxins; Myocardium; Oxazoles; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Sulfonamides | 1997 |
Beta-adrenergic receptor signalling in stunned myocardium of conscious pigs.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Coronary Vessels; Epinephrine; Immunoblotting; Isoproterenol; Myocardial Stunning; Myocardium; Norepinephrine; Receptors, Adrenergic, beta; Reperfusion; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Swine; Sympathetic Nervous System | 1997 |
In vivo evidence that GABA(B) receptors are negatively coupled to adenylate cyclase in rat striatum.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Baclofen; Colforsin; Corpus Striatum; Cyclic AMP; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Isoproterenol; Locomotion; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Signal Transduction | 1997 |
Right ventricular infundibular beta-adrenoceptor complex in tetralogy of Fallot patients.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Child; Child, Preschool; Colforsin; Female; Guanosine Triphosphate; Heart Ventricles; Humans; Hypoxia; Imidazoles; In Vitro Techniques; Infant; Isoproterenol; Male; Myocardium; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sodium Fluoride; Tetralogy of Fallot | 1997 |
Stimulation of anion secretion by beta-adrenoceptors in the mouse endometrial epithelium.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic Agonists; Adrenergic Antagonists; Animals; Anions; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Endometrium; Epinephrine; Epithelium; Female; Glyburide; Imines; Ion Transport; Isoproterenol; Mice; Propranolol; Receptors, Adrenergic, beta | 1997 |
Angiotensinogen gene expression is stimulated by the cAMP-responsive element binding protein in opossum kidney cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensinogen; Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA Primers; DNA, Complementary; Gene Expression; Genes, Reporter; Human Growth Hormone; Humans; Isoproterenol; Kidney; Opossums; Propranolol; Rats; Thionucleotides; Transfection | 1997 |
Differential regulation of adenylyl cyclase in fibroblasts from sporadic and familial Alzheimer's disease cases with PS1 and APP mutations.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Cell Line; Colforsin; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Isoproterenol; Male; Membrane Proteins; Middle Aged; Mutation; Presenilin-1; Signal Transduction; Skin | 1997 |
Effects of magnesium cardioplegia on regulation of the porcine coronary circulation.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Calcimycin; Cardioplegic Solutions; Cold Temperature; Colforsin; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Isoproterenol; Magnesium; Male; Microcirculation; Muscle, Smooth, Vascular; Nitroprusside; Swine; Vasodilation | 1997 |
Discrepancy between inotropic response and cyclic AMP production induced by isoprenaline and forskolin in rat ventricle strips.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Female; Isoproterenol; Male; Muscle Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Ventricular Function, Right | 1997 |
A role for neurotransmitters in early follicular development: induction of functional follicle-stimulating hormone receptors in newly formed follicles of the rat ovary.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Aromatase; Base Sequence; Colforsin; DNA Primers; Female; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; In Situ Hybridization; Isoproterenol; Neurotransmitter Agents; Norepinephrine; Organ Culture Techniques; Ovarian Follicle; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, FSH; RNA, Messenger; Vasoactive Intestinal Peptide | 1997 |
The mechanisms of compound 48/80-induced superoxide generation mediated by A-kinase in rat peritoneal mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Bucladesine; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Granulomatous Disease, Chronic; Immunohistochemistry; Indoles; Isoproterenol; Male; Mast Cells; NADPH Oxidases; p-Methoxy-N-methylphenethylamine; Phosphoproteins; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Terpenes | 1997 |
Cellular basis of contractile derangements of hypertrophied feline ventricular myocytes.
Topics: Actin Cytoskeleton; Animals; Calcium; Cardiomegaly; Cats; Colforsin; Fluorescent Dyes; Hemodynamics; In Vitro Techniques; Indoles; Isoproterenol; Myocardial Contraction | 1997 |
Beta-adrenergic stimulation down-regulates neutrophil priming for superoxide generation, but not elastase release.
Topics: Adrenergic beta-Agonists; Cells, Cultured; Colforsin; Down-Regulation; Humans; Isoproterenol; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Adrenergic, beta; Superoxides | 1997 |
cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle.
Topics: Animals; Aorta; Blood Platelets; Bucladesine; Carbon Monoxide; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoproterenol; Muscle, Smooth, Vascular; omega-N-Methylarginine; Polymerase Chain Reaction; Protoporphyrins; Rats; RNA, Messenger; Transcription, Genetic | 1997 |
Na-K-2Cl cotransporters are present and regulated in simian eccrine clear cells.
Topics: Amiloride; Animals; Bumetanide; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Eccrine Glands; Hand; Homeostasis; Humans; Hypertonic Solutions; Hypotonic Solutions; Isoproterenol; Macaca mulatta; Methacholine Chloride; Ouabain; Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Expression of functional beta-adrenoceptors and polyploidy development in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Age Factors; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Muscle, Smooth, Vascular; Polyploidy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 1997 |
Expression of adenylyl cyclase mRNAs in the adult, in developing, and in the Brattleboro rat kidney.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Arginine Vasopressin; Calcium; Cell Membrane; Colforsin; DNA Probes; Female; Fetus; Isoenzymes; Isoproterenol; Kidney; Kidney Cortex; Kidney Medulla; Kinetics; Male; Organ Specificity; Parathyroid Hormone; Polymerase Chain Reaction; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1997 |
Effects of melatonin in isolated rat papillary muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred WKY; Stimulation, Chemical | 1997 |
Cardiopulmonary bypass alters vasomotor regulation of the skeletal muscle microcirculation.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiopulmonary Bypass; Colforsin; Deferoxamine; Guanylate Cyclase; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Isoproterenol; Isotonic Solutions; Microcirculation; Muscle, Skeletal; Nitroprusside; Ringer's Lactate; Sheep; Vasoconstriction; Vasodilation; Vasomotor System | 1997 |
Interactions between neuropeptide Y and the adenylate cyclase pathway in rat mesenteric small arteries: role of membrane potential.
Topics: 4-Aminopyridine; Acetylcholine; Adenylyl Cyclases; Animals; Charybdotoxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Gadolinium; Glyburide; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Nifedipine; Potassium Channels; Rats; Rats, Wistar; Thionucleotides | 1997 |
Activation of a beta 2-adrenergic receptor/Gs alpha fusion protein elicits a desensitization-resistant cAMP signal capable of inhibiting proliferation of two cancer cell lines.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Colforsin; Cyclic AMP; Down-Regulation; Gene Expression Regulation, Neoplastic; GTP-Binding Protein alpha Subunits, Gs; Iodocyanopindolol; Isoproterenol; Mice; Pindolol; ras Proteins; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Salmeterol Xinafoate; Signal Transduction; Transfection; Tumor Cells, Cultured | 1997 |
Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cytosol; Enzyme Inhibitors; Homeostasis; Isoproterenol; Kinetics; Microglia; Naphthalenes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Response and level of beta-adrenergic, vasoactive intestinal peptide, and PACAP receptors during the circadian cycle.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Aqueous Humor; Ciliary Body; Circadian Rhythm; Clonidine; Colforsin; Cyclic AMP; Isoproterenol; Ligands; Male; Rabbits; Receptors, Adrenergic, beta; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Vasoactive Intestinal Peptide | 1997 |
Gallbladder relaxation in patients with pigment and cholesterol stones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cholelithiasis; Cholesterol; Colforsin; Cyclic AMP; Cyclic GMP; Electric Stimulation; Enzyme Activation; Gallbladder; Humans; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pigments, Biological; Vasoactive Intestinal Peptide | 1997 |
Biomechanical coupling in renin-releasing cells.
Topics: Animals; Cells, Cultured; Colforsin; Enzyme Precursors; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; In Situ Hybridization; Isoproterenol; Juxtaglomerular Apparatus; Lung; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Stress, Physiological; Tumor Cells, Cultured | 1997 |
G-proteins and beta-adrenergic stimulation of adenylate cyclase activity in the diabetic rat prostate.
Topics: Acetates; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Immunoblotting; Insulin; Isoproterenol; Lipid Metabolism; Male; Prostate; Rats; Rats, Wistar | 1997 |
Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Bucladesine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Isoproterenol; Myocardium; Protein Biosynthesis; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar | 1997 |
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection | 1997 |
Inhibitory effects of Gs on desensitization of beta-adrenergic receptors in tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Isoproterenol; Kinetics; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta; Thionucleotides; Time Factors; Trachea | 1997 |
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Heart; Heart Ventricles; Hypertension; Isoproterenol; Marine Toxins; Myocardial Contraction; Myocardium; Myosin Light Chains; Norepinephrine; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Troponin I | 1997 |
Localized cAMP-dependent signaling mediates beta 2-adrenergic modulation of cardiac excitation-contraction coupling.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Ethanolamines; Heart; Heart Ventricles; Imidazoles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic, beta-2; Signal Transduction; Thionucleotides | 1997 |
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Indoles; Isomerism; Isoproterenol; Kinetics; Liver; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate | 1997 |
Targeted disruption of Gnas in embryonic stem cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Northern; Blotting, Southern; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Genetic Vectors; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Mice; Signal Transduction; Stem Cells; Transfection | 1997 |
Cardiac G-protein receptor kinase activity: effect of a beta-adrenergic receptor antagonist.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aluminum Compounds; Animals; Binding, Competitive; Bisoprolol; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Myocardium; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Swine | 1998 |
Repeated topical administration of fenoterol in rabbit reverses its initial ocular hypotensive effect and decreases sensitivity of adenylyl cyclase in ciliary processes to stimulatory agents.
Topics: Adenylyl Cyclases; Administration, Topical; Adrenergic beta-Agonists; Animals; Ciliary Body; Colforsin; Fenoterol; Intraocular Pressure; Isoproterenol; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Tonometry, Ocular; Vasoactive Intestinal Peptide | 1997 |
Cyclic AMP-mediated inhibition of angiotensin II-induced protein synthesis is associated with suppression of tyrosine phosphorylation signaling in vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Humans; Isoproterenol; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Ribosomal Protein S6 Kinases; Signal Transduction; Transfection; Type C Phospholipases | 1997 |
RU-486 (Mifepristone) ameliorates diabetes but does not correct deficient beta-adrenergic signalling in adipocytes from mature C57BL/6J-ob/ob mice.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Colforsin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; Ethanolamines; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunits, Gs; Hormone Antagonists; Insulin; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mifepristone; Monosaccharide Transport Proteins; Muscle Proteins; Phenotype; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Signal Transduction | 1997 |
Molecular characterization and differential gene induction of the neuroendocrine-specific genes neurotensin, neurotensin receptor, PC1, PC2, and 7B2 in the human ocular ciliary epithelium.
Topics: Aspartic Acid Endopeptidases; Cell Line; Ciliary Body; Colforsin; Dexamethasone; DNA Primers; Enzyme Induction; Epithelial Cells; Furin; Gene Expression Regulation; Humans; Isoproterenol; Models, Biological; Nerve Growth Factors; Neurosecretory Systems; Neurotensin; Polymerase Chain Reaction; Proprotein Convertase 2; Proprotein Convertases; Receptors, Neurotensin; Subtilisins; Tetradecanoylphorbol Acetate; Timolol; Transcriptional Activation; Up-Regulation | 1997 |
Phosphorylation of inhibitory subunit of troponin and phospholamban in rat cardiomyocytes: modulation by exposure of cardiomyocytes to hydroxyl radicals and sulfhydryl group reagents.
Topics: Adenosine Triphosphatases; Animals; Autoradiography; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Free Radicals; Heart Ventricles; Hydroxyl Radical; Isoproterenol; Male; Oxidation-Reduction; Phosphorylation; Rats; Scintillation Counting; Sulfhydryl Compounds; Sulfhydryl Reagents; Troponin I | 1997 |
The vascular smooth muscle type I angiotensin II receptor mRNA is destabilized by cyclic AMP-elevating agents.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Isoproterenol; Muscle, Smooth, Vascular; Rats; Receptors, Angiotensin; RNA, Messenger | 1997 |
Regulation of CREB phosphorylation by cAMP and Ca2+ in parotid acinar cells.
Topics: Adrenergic beta-Agonists; Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Immunoblotting; Isoproterenol; Muscarinic Agonists; Parotid Gland; Phosphorylation; Rats | 1997 |
cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Capillaries; Cattle; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Isoproterenol; Isoquinolines; Lymphokines; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-raf; Signal Transduction; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
Ontogenic development of the adenylyl cyclase enzyme and the alpha s, alpha i1 and alpha i2 G-protein regulatory subunits from rat prostate.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Blotting, Northern; Colforsin; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Prostate; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Testosterone; Transcription, Genetic; Vasoactive Intestinal Peptide | 1997 |
Effect of phospholipase A2 activation on the receptor function in the rat left atrium: unmasking of a positive inotropic effect of methacholine.
Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Colforsin; Enzyme Activation; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Melitten; Methacholine Chloride; Muscarinic Agonists; Myocardial Contraction; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar; Receptors, Neurotransmitter | 1997 |
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents | 1997 |
Myocardial action potential prolongation by calcium channel activation under calcium free-EGTA conditions in guinea-pigs: developmental and regional variations.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Egtazic Acid; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Phosphodiesterase Inhibitors | 1997 |
Molecular diversity of adenylyl cyclases in human and rat myometrium. Correlation with global adenylyl cyclase activity during mid- and term pregnancy.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Humans; Isoproterenol; Myometrium; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Rats; Rats, Sprague-Dawley; Sympathomimetics; Transducin | 1997 |
Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.
Topics: Allosteric Regulation; Allosteric Site; Animals; Cats; Cell Line; Cerebrosides; Clozapine; Colforsin; Cyclic AMP; GTP-Binding Proteins; HeLa Cells; Humans; Isoproterenol; Oleic Acids; Phosphatidylinositols; Rats; Receptors, Serotonin; Serotonin; Signal Transduction | 1997 |
G-protein-coupled receptor agonists augment adenylyl cyclase activity induced by forskolin in human corpus cavernosum smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cells, Cultured; Colforsin; Drug Interactions; Enzyme Activation; GTP-Binding Proteins; Humans; Isoproterenol; Male; Models, Biological; Muscle Relaxation; Muscle, Smooth, Vascular; Penis; Phenylephrine; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cholinergic; Signal Transduction | 1997 |
Forskolin potentiates isoprenaline-induced glycerol output and local blood flow in human adipose tissue in vivo.
Topics: Adipose Tissue; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Colforsin; Ethanol; Female; Glycerol; Humans; Isoproterenol; Male; Microdialysis; Middle Aged; Regional Blood Flow | 1997 |
Site-specific fluorescence labeling of the beta2 adrenergic receptor amino terminus.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Colforsin; Enzyme Activation; Factor Xa; Fluorescamine; Fluorescent Dyes; Hemagglutinins; Histidine; Humans; Isoproterenol; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Peptides; Protein Sorting Signals; Receptors, Adrenergic, beta-2; Recombinant Proteins; Spectrometry, Fluorescence; Spodoptera | 1997 |
Roles of PKA and PKC in regulation of Na+ pump activity in vascular smooth muscle cells.
Topics: Animals; Aorta; Arginine Vasopressin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Homeostasis; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine | 1997 |
cGMP facilitates calcium current via cGMP-dependent protein kinase in isolated rabbit ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Channels; Colforsin; Cyclic GMP; Electric Conductivity; Enzyme Inhibitors; Female; Heart; Isoproterenol; Male; Membrane Potentials; Protein Kinases; Rabbits; Thionucleotides | 1998 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1998 |
Calcium-stimulated Cl- secretion in Calu-3 human airway cells requires CFTR.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bumetanide; Calcium; Carbachol; Cell Line; Cell Membrane; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelial Cells; Humans; Isoproterenol; Kinetics; Lung; Models, Biological; Thapsigargin | 1997 |
Beta-adrenoceptor-coupled Gs protein facilitates the activation of cAMP-dependent cardiac Cl- current.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dialysis; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Kinetics; Membrane Potentials; Rana pipiens; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Thionucleotides | 1997 |
Cardiac beta-adrenergic receptor function in fetal sheep exposed to long-term high-altitude hypoxemia.
Topics: Adrenergic beta-Agonists; Altitude; Animals; Colforsin; Cyclic AMP; Female; Fetus; Heart; Heart Ventricles; Hypoxia; Isoproterenol; Myocardial Contraction; Organ Size; Papillary Muscles; Pregnancy; Pregnancy Complications; Receptors, Adrenergic, beta; Reference Values; Sheep | 1997 |
Effect of sensory denervation on the structure and physiologic responsiveness of rabbit lacrimal gland.
Topics: Animals; Carbachol; Cells, Cultured; Colforsin; Eye Proteins; Ganglionectomy; Isoproterenol; Lacrimal Apparatus; Male; Phorbol 12,13-Dibutyrate; Rabbits; Sympathomimetics; Trigeminal Ganglion | 1998 |
L-type Ca2+ current in fish cardiac myocytes: effects of thermal acclimation and beta-adrenergic stimulation.
Topics: Acclimatization; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Barium; Caffeine; Calcium; Carps; Colforsin; Heart; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Microscopy, Electron; Nifedipine; Oncorhynchus mykiss; Sarcolemma; Species Specificity; Temperature | 1998 |
Modulation of the cardiac sodium current by inhalational anesthetics in the absence and presence of beta-stimulation.
Topics: Anesthetics, Inhalation; Animals; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guinea Pigs; Heart; Isoproterenol; Receptors, Adrenergic, beta; Sodium Channels | 1998 |
Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Colforsin; Heart Arrest, Induced; Isoproterenol; Myocardial Contraction; Receptors, Adrenergic, beta; Signal Transduction; Swine; Time Factors; Ventricular Dysfunction, Left | 1998 |
Beta-adrenergic signal transduction and contractility in the canine heart after cardiopulmonary bypass.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cardiopulmonary Bypass; Cell Membrane; Colforsin; Dogs; GTP-Binding Proteins; Immunoblotting; Isoproterenol; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Postoperative Period; Radioligand Assay; Receptors, Adrenergic, beta; Signal Transduction | 1997 |
Cyclic AMP in cells adhering to bioincompatible (Cuprophan) and biocompatible (AN69) substrates.
Topics: 3T3 Cells; Acrylic Resins; Acrylonitrile; Adrenergic beta-Agonists; Animals; Biocompatible Materials; Cell Adhesion; Cellulose; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Membranes, Artificial; Mice; Microscopy, Electron, Scanning | 1998 |
Adrenergic-mediated connexin43 phosphorylation in the ocular ciliary epithelium.
Topics: Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Blotting, Western; Ciliary Body; Colforsin; Connexin 43; Cyclic AMP; Epithelial Cells; Fluorescent Antibody Technique, Indirect; Isoproterenol; Phosphorylation; Pigment Epithelium of Eye; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1998 |
Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Aorta; Cobalt; Colforsin; Cyclic AMP; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Iloprost; Isoproterenol; Lymphokines; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Modification of cardiac beta-adrenoceptor mechanisms by H2O2.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Catalase; Cell Membrane; Colforsin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart; Hydrogen Peroxide; Isoproterenol; Kinetics; Mannitol; Myocardium; Oxidative Stress; Rats; Receptors, Adrenergic, beta; Sodium Fluoride | 1998 |
Effects of the Aconitum alkaloid mesaconitine in rat hippocampal slices and the involvement of alpha- and beta-adrenoceptors.
Topics: Aconitine; Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Hippocampus; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1998 |
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
Topics: Acetylcholine; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Cardiac Output, Low; Colforsin; Cyclic AMP; Cyclic GMP; Hemodynamics; Indoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1998 |
Catecholamines modulate podocyte function.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Catecholamines; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Epithelial Cells; Ionophores; Isoproterenol; Kidney Glomerulus; Mice; Mice, Transgenic; Nicardipine; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-2 | 1998 |
Relaxant effects of NKH477, a new water-soluble forskolin derivative, on guinea-pig tracheal smooth muscle: the role of Ca2+-activated K+ channels.
Topics: Animals; Bronchodilator Agents; Calcium; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Peptides; Potassium; Potassium Channels; Solubility; Trachea; Water | 1998 |
Age-related decline in beta adrenergic and adenosine A1 receptor function in the heart are attenuated by dietary restriction.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Colforsin; Cyclic AMP; Diet; GTP-Binding Proteins; Heart; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Receptors, Purinergic P1 | 1998 |
Altered calcium handling in compensated hypertrophied rat cardiomyocytes induced by pressure overload.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiomegaly; Cells, Cultured; Colforsin; Heart; Hemodynamics; Homeostasis; Hypertension; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Rats; Rats, Wistar | 1998 |
Activation of cardiac EP3 receptors by PGE1 reduces beta-adrenergic inotropic effects.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprostadil; Animals; Colforsin; Cyclic AMP; Isoproterenol; Myocardial Contraction; Myocardium; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Sarcolemma; Swine; Swine, Miniature; Tritium; Ventricular Function, Left | 1997 |
Cyclic AMP potentiates substance P-induced amylase secretion by augmenting the effect of calcium in the rat parotid acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; 2,4-Dinitrophenol; Amylases; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Parotid Gland; Perfusion; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Substance P; Thapsigargin | 1998 |
Adenosine 3':5'-cyclic monophosphate induces regulated secretion of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Bucladesine; Calcium; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Isoproterenol; Second Messenger Systems; Secretory Rate; Thrombin; Tissue Plasminogen Activator; von Willebrand Factor | 1998 |
Developmental change in isoproterenol-mediated relaxation of pulmonary veins of fetal and newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Fetus; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Propranolol; Pulmonary Veins; Sheep | 1998 |
Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists.
Topics: Animals; Bethanechol; Carbon Monoxide; Colforsin; Esophagogastric Junction; Heme Oxygenase (Decyclizing); In Vitro Techniques; Isoproterenol; Muscle Relaxation; Nitric Oxide; Opossums; Protoporphyrins; Vasoactive Intestinal Peptide | 1998 |
Effect of alpha2-adrenoceptor stimulation on isolated canine Purkinje fiber contraction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Colforsin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Purkinje Fibers; Virulence Factors, Bordetella | 1998 |
Na+,K(+)-ATPase phosphorylation in the choroid plexus: synergistic regulation by serotonin/protein kinase C and isoproterenol/cAMP-PK/PP-1 pathways.
Topics: Adrenergic beta-Agonists; Animals; Carrier Proteins; Choroid Plexus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Synergism; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Nerve Tissue Proteins; Okadaic Acid; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Serotonin; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 1998 |
Reconstitution of beta-adrenergic modulation of large conductance, calcium-activated potassium (maxi-K) channels in Xenopus oocytes. Identification of the camp-dependent protein kinase phosphorylation site.
Topics: Animals; Binding Sites; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Electrophysiology; Gene Expression; Isoproterenol; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Microinjections; Mutagenesis; Oocytes; Patch-Clamp Techniques; Peptides; Phosphorylation; Phosphoserine; Potassium Channels; Potassium Channels, Calcium-Activated; Receptors, Adrenergic, beta-2; Xenopus | 1998 |
Sex differences in function and distribution of beta-adrenoceptors in rabbit urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Female; Isoproterenol; Male; Rabbits; Receptors, Adrenergic, beta; Sex Characteristics; Urinary Bladder | 1998 |
Vasoactive intestinal peptide enhances its own expression in sympathetic neurons after injury.
Topics: Animals; Axotomy; Cells, Cultured; Colforsin; Cyclic AMP; Feedback; Isoproterenol; Male; Neurons; Organ Culture Techniques; Peptide Fragments; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stimulation, Chemical; Superior Cervical Ganglion; Vasoactive Intestinal Peptide | 1998 |
M2 muscarinic receptors inhibit forskolin- but not isoproterenol-mediated relaxation in bovine tracheal smooth muscle.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diphenylacetic Acids; Histamine; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Oxotremorine; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea | 1998 |
Beta3-adrenergic relaxation of bovine iris sphincter.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bupranolol; Cattle; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ethanolamines; Iris; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1998 |
Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; In Vitro Techniques; Isoproterenol; Juxtaglomerular Apparatus; Kidney; Kidney Glomerulus; Mice; Microscopy, Immunoelectron; Rats; Rats, Sprague-Dawley; Renin | 1998 |
Molecular mechanisms of adenylyl cyclase desensitization in pregnant rat myometrium following in vivo administration of the beta-adrenergic agonist, isoproterenol.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Drug Tolerance; Female; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Myometrium; Pindolol; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Accumulation of cAMP augments dynamic vagal control of heart rate.
Topics: Animals; Blood Pressure; Colforsin; Cyclic AMP; Electric Stimulation; Heart Rate; Isoproterenol; Mathematics; Models, Cardiovascular; Pulse; Rabbits; Theophylline; Vagus Nerve | 1998 |
Cyclic AMP potentiates growth hormone-dependent differentiation of 3T3-F442A preadipocytes: possible involvement of the transcription factor CREB.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Glycerolphosphate Dehydrogenase; Growth Hormone; Ionomycin; Isoproterenol; Kinetics; Mice; Recombinant Proteins; Thionucleotides; Transcription Factors | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; Colforsin; Dexamethasone; Fluorides; Glucocorticoids; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kidney; Male; Manganese; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Characterization of cyclic AMP efflux from swine adipocytes in vitro.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Antimycin A; Cells, Cultured; Colforsin; Cyclic AMP; Isoproterenol; Probenecid; Quinolones; Swine; Swine, Miniature; Xanthines | 1998 |
Inhibition of voltage-activated K+ currents in smooth muscle cells of the guinea pig proximal colon by noradrenergic agonists.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic Agonists; Animals; Calcium Channels; Colforsin; Colon; Guinea Pigs; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channels | 1998 |
A luciferase-engineered cell line for study of cAMP regulation in endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Aorta; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Isoproterenol; Isoquinolines; Kinetics; Luciferases; Rabbits; Signal Transduction; Sulfonamides; Transfection | 1998 |
Functional coupling of overexpressed beta 1-adrenoceptors in the myocardium of transgenic mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Crosses, Genetic; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart; Heart Atria; Humans; Isoproterenol; Kinetics; Manganese Compounds; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Myocardial Contraction; Myocardium; Pertussis Toxin; Receptors, Adrenergic, beta-1; Signal Transduction; Virulence Factors, Bordetella | 1998 |
The effects of adrenergic agonists on intraocular pressure and on adenylyl cyclase activity of ciliary processes in pigmented rabbits.
Topics: Adenylyl Cyclases; Administration, Topical; Adrenergic beta-Agonists; Animals; Ciliary Body; Clenbuterol; Colforsin; Drug Resistance; Fenoterol; Intraocular Pressure; Isoproterenol; Rabbits; Vasoactive Intestinal Peptide | 1998 |
Molecular mechanism(s) of action of norepinephrine on the expression of the angiotensinogen gene in opossum kidney cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensinogen; Animals; Colforsin; Estrenes; Isoproterenol; Kidney; Norepinephrine; Opossums; Pyrrolidinones; Tetradecanoylphorbol Acetate | 1998 |
Stepwise activation of the gonadotropic signal transduction pathway, and the ability of prostaglandin F2alpha to inhibit this activated pathway.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bucladesine; Cattle; Cells, Cultured; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; DNA; Female; Granulosa Cells; GTP-Binding Proteins; Humans; Isoproterenol; Signal Transduction | 1998 |
Developmental enhancement of secretory response to isoproterenol coupled with increases in beta-adrenoceptor density and Gs protein function in rat parotid tissues.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Culture Techniques; Female; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Organ Size; Parotid Gland; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1998 |
Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding.
Topics: Animals; Cells, Cultured; Colforsin; Hypertension; Isoproterenol; Nerve Growth Factors; Neuronal Plasticity; Neuropeptide Y; Phenylephrine; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Tetradecanoylphorbol Acetate; Urinary Bladder; Urination; Urination Disorders | 1998 |
Heterologous regulation of muscarinic and beta-adrenergic receptors in rat cardiomyocytes in culture.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Female; Indoles; Isoproterenol; Isoquinolines; Kinetics; Male; Maleimides; Muscarinic Agonists; Myocardium; N-Methylscopolamine; Propanolamines; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Sulfonamides; Thionucleotides; Tritium | 1998 |
Depletion of protein kinase C-alpha by antisense oligonucleotides alters beta-adrenergic function and reverses the phorbol ester-induced reduction of isoproterenol-induced adenosine 3'-5'-cyclic monophosphate accumulation in murine Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cholera Toxin; Colforsin; Cyclic AMP; Indoles; Isoenzymes; Isoproterenol; Maleimides; Mice; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Physiological and biochemical adrenergic regulation of the stunned myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Coronary Circulation; Isoproterenol; Myocardial Contraction; Myocardial Stunning; Myocardium; Receptors, Adrenergic, beta; Signal Transduction; Swine | 1998 |
ATP-sensitive K+ channels in smooth muscle cells of guinea-pig mesenteric lymphatics: role in nitric oxide and beta-adrenoceptor agonist-induced hyperpolarizations.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Isoquinolines; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Sulfonamides | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
A synergistic interaction between histamine and vasoactive intestinal peptide (VIP) on cyclic AMP production in the chick pineal gland.
Topics: Amino Acid Sequence; Animals; Chickens; Colforsin; Cyclic AMP; Drug Synergism; Histamine; Isoproterenol; Molecular Sequence Data; Pineal Gland; Retina; Vasoactive Intestinal Peptide | 1998 |
Cultured astrocytes express messenger RNA for multiple serotonin receptor subtypes, without functional coupling of 5-HT1 receptor subtypes to adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Cerebral Cortex; Colforsin; Cyclic AMP; Female; Hypothalamus; Isoproterenol; Male; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Receptor Agonists; Thalamus | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors | 1998 |
Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation.
Topics: Adrenergic beta-Agonists; Anesthetics, Dissociative; Animals; Cell Line; Colforsin; Cyclic AMP; Cytokines; Inflammation; Intracellular Fluid; Isoproterenol; Ketamine; Myocardium; Rats; Receptors, Adrenergic, beta; Tumor Necrosis Factor-alpha | 1998 |
Endotoxin differentially impairs receptor-mediated relaxation in rat isolated pulmonary and thoracic aortic vessels.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Circulation; Blood Pressure; Colforsin; Dimaprit; Dose-Response Relationship, Drug; Endotoxins; Histamine Agonists; Isoproterenol; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Salmonella typhi; Vascular Resistance; Vasodilation | 1998 |
Effects of halothane and isoflurane on beta-adrenoceptor-mediated responses in the vascular smooth muscle of rat aorta.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Halothane; In Vitro Techniques; Isoflurane; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1998 |
Carbachol inhibition of Ca2+ currents in ventricular cells obtained from neonatal and adult rats.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Carbachol; Cardiotonic Agents; Colforsin; Dose-Response Relationship, Drug; Electric Conductivity; GTP-Binding Proteins; Heart Ventricles; Isoproterenol; Membrane Potentials; Muscarinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Ventricular Function | 1998 |
Characteristics of amylase secretion induced by various secretagogues examined in perifused rat parotid acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Bucladesine; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Epithelial Cells; Isoproterenol; Male; Norepinephrine; Parasympatholytics; Parotid Gland; Rats; Rats, Wistar; Substance P; Sympathomimetics; Temperature | 1998 |
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.
Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems | 1998 |
Acetylcholine-induced biphasic effect on the maximum upstroke velocity of action potential in mouse right atria: interaction with beta-adrenergic signaling cascade.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Action Potentials; Adenylate Cyclase Toxin; Adjuvants, Immunologic; Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Isoquinolines; Kinetics; Male; Mice; Muscarinic Agonists; Naphthalenes; Oxotremorine; Protein Kinase C; Receptors, Adrenergic, beta; Sulfonamides; Virulence Factors, Bordetella | 1998 |
Post-rest contraction amplitude in myocytes from failing human ventricle.
Topics: Analysis of Variance; Calcium; Cardiac Output, Low; Cardiotonic Agents; Colforsin; Digoxigenin; Drug Evaluation, Preclinical; Heart Ventricles; Humans; In Vitro Techniques; Isoproterenol; Linear Models; Myocardial Contraction; Rest; Thapsigargin | 1998 |
Microvascular permeability and number of tight junctions are modulated by cAMP.
Topics: Adrenergic beta-Agonists; Animals; Capillary Permeability; Colforsin; Cyclic AMP; Hemorheology; Isoproterenol; Lymphatic System; Male; Pyrrolidinones; Rana pipiens; Rolipram; Tight Junctions | 1998 |
Regulation of the GTP-binding protein-based antilipolytic system of sheep adipocytes by growth hormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cell Membrane; Colforsin; Culture Techniques; Enzyme Inhibitors; Growth Hormone; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isomerism; Isoproterenol; Lipolysis; Male; Models, Biological; Okadaic Acid; Pertussis Toxin; Phenylisopropyladenosine; Protein Binding; Receptors, Purinergic P1; Sheep; Stimulation, Chemical; Virulence Factors, Bordetella | 1998 |
Isoprenaline can activate the acetylcholine-induced K+ current in canine atrial myocytes via Gs-derived betagamma subunits.
Topics: Acetylcholine; Adenoviridae; Adenylate Cyclase Toxin; Animals; beta-Galactosidase; Carbachol; Cells, Cultured; Colforsin; Dogs; GTP-Binding Protein alpha Subunits, Gs; Heart; Heart Atria; Isoproterenol; Macromolecular Substances; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Receptors, Adrenergic, beta; Recombinant Proteins; Signal Transduction; Transfection; Virulence Factors, Bordetella | 1999 |
Neurotensin enhances agonist-induced cAMP accumulation in PC3 cells via Ca2+ -dependent adenylyl cyclase(s).
Topics: Adenylyl Cyclases; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Egtazic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ionomycin; Isoproterenol; Male; Neurotensin; Prostatic Neoplasms; Thapsigargin; Tumor Cells, Cultured; Uridine Triphosphate | 1998 |
Role of vasoactive intestinal polypeptide in the adaptation of intestinal smooth muscle cells to mechanical distension.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Animals; Cell Separation; Colforsin; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Diseases; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Receptors, Vasoactive Intestinal Peptide; Sincalide; Stress, Mechanical; Vasoactive Intestinal Peptide | 1998 |
Beta-adrenergic signal transduction following carvedilol treatment in hypertensive cardiac hypertrophy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Genetically Modified; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Colforsin; Down-Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanylyl Imidodiphosphate; Heart Rate; Isoproterenol; Male; Neuropeptide Y; Pertussis Toxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Virulence Factors, Bordetella | 1998 |
Cross-modulation of synaptic plasticity by beta-adrenergic and 5-HT1A receptors in the rat basolateral amygdala.
Topics: Adrenergic beta-Agonists; Amygdala; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Excitatory Postsynaptic Potentials; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Synapses | 1999 |
Molecular and cellular analyses of melatonin receptor-mediated cAMP signaling in rat corpus epididymis.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dihydrotestosterone; DNA Primers; Epididymis; Epithelial Cells; GTP-Binding Proteins; In Situ Hybridization; Isoproterenol; Male; Melatonin; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 1998 |
Endothelial defect mediates attenuated vasorelaxant response to isoproterenol after lung transplantation.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isoproterenol; Lung Transplantation; Oxypurinol; Pulmonary Artery; Transplantation, Autologous; Vasodilation | 1999 |
Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of alpha-subunits in lung alveolar cells.
Topics: Adrenergic beta-Agonists; Animals; Brefeldin A; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Endosomes; Isoenzymes; Isoproterenol; Male; Peptides, Cyclic; Phosphorylation; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Time Factors | 1999 |
An inverted cAMP response element mediates the cAMP induction of the ovine beta 1-adrenergic receptor gene.
Topics: Animals; Base Sequence; Binding Sites; Bucladesine; Cell Line; Colforsin; Consensus Sequence; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Genes, Reporter; Humans; Isoproterenol; Luciferases; Macaca mulatta; Mice; Oligodeoxyribonucleotides; Protein Biosynthesis; Rats; Receptors, Adrenergic, alpha-1; Recombinant Fusion Proteins; Sequence Alignment; Sheep; Transcription, Genetic; Transfection | 1998 |
Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bupranolol; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Dioxoles; Enzyme Activation; Epinephrine; Ethanolamines; Humans; Insulin; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norepinephrine; Phentolamine; Prazosin; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Signal Transduction; Yohimbine | 1999 |
Establishment of beta-adrenergic modulation of L-type Ca2+ current in the early stages of cardiomyocyte development.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium Channels; Cell Differentiation; Colforsin; Embryonic and Fetal Development; Heart; Isoproterenol; Mice; Patch-Clamp Techniques; Receptors, Adrenergic, beta; Signal Transduction; Stem Cells | 1999 |
beta-adrenergic modulation of L-type Ca2+-channel currents in early-stage embryonic mouse heart.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels; Calcium Channels, L-Type; Colforsin; Electric Conductivity; Embryo, Mammalian; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Mice; Myocardium; Receptors, Adrenergic, beta; Ventricular Function | 1999 |
Genistein inhibits slow component delayed-rectifier K currents via a tyrosine kinase-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Genistein; Heart; In Vitro Techniques; Ion Exchange; Isoflavones; Isoproterenol; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Phenols; Phosphoric Diester Hydrolases; Potassium Channels; Protein-Tyrosine Kinases; Swine; Time Factors; Tyrphostins; Vanadates | 1998 |
Is visceral adiposity a significant correlate of subcutaneous adipose cell lipolysis in men?
Topics: Abdomen; Adenosine Deaminase; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Body Constitution; Bucladesine; Colforsin; Epinephrine; Glucose Tolerance Test; Humans; Insulin; Isoproterenol; Lipolysis; Male; Obesity; Receptors, Adrenergic, beta; Theophylline | 1999 |
Endocrine regulation of fetal adipose tissue metabolism in the pig: interaction of porcine growth hormone and thyroxine.
Topics: Adipose Tissue; Animals; Bronchodilator Agents; Bucladesine; Colforsin; Embryonic and Fetal Development; Female; Growth Hormone; Hypophysectomy; Insulin-Like Growth Factor I; Isoproterenol; Lipolysis; Luteinizing Hormone; Pregnancy; Radioimmunoassay; Swine; Thyroxine | 1999 |
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.
Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 1999 |
Alpha2-adrenoceptor-mediated enhancement of glycine response in rat sacral dorsal commissural neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Bucladesine; Clonidine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Glycine; Glycine Agents; GTP-Binding Proteins; Ion Channel Gating; Isoproterenol; Lumbosacral Region; Neurons, Afferent; Nociceptors; Norepinephrine; Pertussis Toxin; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Strychnine; Virulence Factors, Bordetella | 1999 |
Alterations in cardiac membrane beta-adrenoceptors and adenylyl cyclase due to hypochlorous acid.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypochlorous Acid; Immunoblotting; Isoproterenol; Lipid Peroxidation; Methionine; Myocardium; Pertussis Toxin; Pindolol; Propane; Rats; Receptors, Adrenergic; Sodium Fluoride; Virulence Factors, Bordetella | 1999 |
Pertussis toxin increases isoproterenol induced relaxation in field-stimulated ileum.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Histamine; Histamine Agonists; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Sympathomimetics; Virulence Factors, Bordetella | 1999 |
The effect of hydrogen peroxide upon beta-adrenoceptor density and function in C6 rat glioma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cell Death; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Glioma; GTP-Binding Protein alpha Subunits, Gs; Hydrogen Peroxide; Isoproterenol; L-Lactate Dehydrogenase; Propanolamines; Rats; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1999 |
Inhibition of phospholipase A2-mediated arachidonic acid release by cyclic AMP defines a negative feedback loop for P2Y receptor activation in Madin-Darby canine kidney D1 cells.
Topics: Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Enzyme Activation; Epinephrine; Feedback; Isoproterenol; Kidney; Phospholipase D; Phospholipases A; Phospholipases A2; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Uridine Triphosphate | 1999 |
Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Colforsin; Dioxoles; Dobutamine; Dose-Response Relationship, Drug; Epinephrine; Ethanolamines; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Inhibition of bronchoprotective effects of beta2-adrenoceptor agonists by peroxynitrite in guinea pig airways.
Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Bronchoconstriction; Colforsin; Guinea Pigs; Isoproterenol; Male; Molsidomine; Nitrates; Penicillamine; Receptors, Adrenergic, beta-1 | 1999 |
Differential regulation of inotropy and lusitropy in overexpressed Gsalpha myocytes through cAMP and Ca2+ channel pathways.
Topics: Animals; Calcium; Calcium Channels; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; Heart Ventricles; Isoproterenol; Kinetics; Mice; Muscle Relaxation; Myocardial Contraction; Patch-Clamp Techniques; Phosphorylation; Receptors, Adrenergic, beta; Signal Transduction | 1999 |
Impaired cholera toxin relaxation with age in rat aorta.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Aging; Animals; Aorta, Thoracic; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Isoproterenol; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred F344; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Line; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Staurosporine | 1999 |
Molecular mechanism(s) of action of isoproterenol on the expression of the angiotensinogen gene in opossum kidney proximal tubular cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Angiotensinogen; Animals; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Human Growth Hormone; Isoproterenol; Kidney Tubules, Proximal; Molecular Sequence Data; Oligonucleotide Probes; Opossums; Plasmids; Rabbits; Rats; Receptors, Adrenergic, beta; Receptors, Angiotensin; Recombinant Proteins; Renin-Angiotensin System; Sequence Homology, Amino Acid; Thionucleotides | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Analysis of ectatomin action on cell membranes.
Topics: Amino Acid Sequence; Animals; Ant Venoms; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Colforsin; Heart; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Molecular Sequence Data; Myocardium; Patch-Clamp Techniques; Rats; Spodoptera; Tumor Cells, Cultured; Verapamil | 1999 |
Pharmacological characterization of effects of UK-1745, a novel cardiotonic agent with beta-adrenoceptor-blocking action, in aequorin-loaded canine right ventricular muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aequorin; Animals; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Heart Ventricles; In Vitro Techniques; Indoles; Isoproterenol; Rabbits | 1999 |
Galanin expression is decreased by cAMP-elevating agents in cultured sympathetic ganglia.
Topics: Animals; Blotting, Northern; Colforsin; Culture Media; Cyclic AMP; Feedback; Galanin; Ganglia, Sympathetic; Gene Expression Regulation; Isoproterenol; Male; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superior Cervical Ganglion; Vasoactive Intestinal Peptide | 1999 |
Lack of involvement of G proteins in the activation of cardiac CFTR Cl- current by genistein.
Topics: Adenylate Cyclase Toxin; Animals; Calcium Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; Heart; Isoproterenol; Pertussis Toxin; Protein-Tyrosine Kinases; Sympathomimetics; Thionucleotides; Virulence Factors, Bordetella | 1999 |
Desensitization of cardiac beta-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins.
Topics: Adrenergic beta-Agonists; Animals; Arrestins; Autoradiography; beta-Adrenergic Receptor Kinases; beta-Arrestins; Blood Pressure; Calcium; Catechols; Colforsin; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Heart Atria; Heart Failure; Heart Ventricles; Isoproterenol; Myocardial Infarction; Organ Size; Pertussis Toxin; Phosphorylation; Propanolamines; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle Proteins; Cell Division; Cell Lineage; Cerebellum; Colforsin; Cyclin D; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Deferoxamine; Ion Channel Gating; Isoproterenol; Membrane Potentials; Mice; Microtubule-Associated Proteins; Oligodendroglia; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sirolimus; Stem Cells; Tetraethylammonium; Tumor Suppressor Proteins; Veratridine | 1999 |
Isoproterenol, forskolin, and cAMP-induced nitric oxide production in pig ciliary processes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Ciliary Body; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Swine | 1999 |
Beta1-adrenergic receptors but not beta2-adrenergic or vasopressin receptors regulate K+ secretion in vestibular dark cells of the inner ear.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Clone Cells; Colforsin; DNA Primers; Ear, Inner; Electric Conductivity; Epinephrine; Epithelial Cells; Gerbillinae; Humans; Isoproterenol; Mice; Molecular Sequence Data; Norepinephrine; Polymerase Chain Reaction; Potassium; Propranolol; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Vasopressin; RNA, Messenger; Transcription, Genetic; Vasopressins; Vestibule, Labyrinth | 1999 |
Cardiac-specific overexpression of the alpha(1) subunit of the L-type voltage-dependent Ca(2+) channel in transgenic mice. Loss of isoproterenol-induced contraction.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Calcium Channels, N-Type; Colforsin; Echocardiography; Female; Heart; Heart Ventricles; Humans; Isoproterenol; Macromolecular Substances; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Ventricular Function, Left | 1999 |
Characterization of beta-adrenoceptor mediated smooth muscle relaxation and the detection of mRNA for beta1-, beta2- and beta3-adrenoceptors in rat ileum.
Topics: Adenylate Cyclase Toxin; Animals; Colforsin; Dioxoles; Dose-Response Relationship, Drug; Ethanolamines; Ileum; Isoproterenol; Male; Muscle Relaxation; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; RNA, Messenger; Virulence Factors, Bordetella | 1999 |
Functional analysis of desensitization of the beta-adrenoceptor signalling pathway in rat cardiac tissues following chronic isoprenaline infusion.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cardiomegaly; Colforsin; Dose-Response Relationship, Drug; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1999 |
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Androgens; Biomarkers; Bombesin; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Lineage; Chromogranin A; Chromogranins; Colforsin; Cyclic AMP; Cytoplasmic Granules; Dihydrotestosterone; Disease Progression; Epinephrine; Humans; Isoproterenol; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neoplastic Stem Cells; Neuroendocrine Tumors; Neurotensin; Parathyroid Hormone-Related Protein; Phenotype; Phosphopyruvate Hydratase; Prostatic Neoplasms; Protein-Tyrosine Kinases; Proteins; Second Messenger Systems; Serotonin; Tumor Cells, Cultured | 1999 |
Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Age Factors; Aging; Animals; Butoxamine; Colforsin; Cromakalim; Data Interpretation, Statistical; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasodilator Agents | 1999 |
Ischemic preconditioning and the beta-adrenergic signal transduction pathway.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Heart; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction | 1999 |
The potentiating effect of genistein on the relaxation induced by isoproterenol in rat aortic rings.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Benzoflavones; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoproterenol; Male; Methoxsalen; Muscle Relaxation; Phosphodiesterase Inhibitors; Quinacrine; Rats; Rats, Wistar; Theophylline | 1999 |
Expression and regulation of type II iodothyronine deiodinase in cultured human skeletal muscle cells.
Topics: Adrenergic beta-Agonists; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Gene Expression Regulation, Enzymologic; Humans; Iodide Peroxidase; Isoproterenol; Muscle, Skeletal; Norepinephrine; RNA, Messenger; Thyroid Hormones; Tumor Necrosis Factor-alpha | 1999 |
Differential effects of epinephrine and norepinephrine on cAMP response and g(i3)alpha protein expression in cultured sympathetic neurons.
Topics: Adrenergic Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Isoproterenol; Neurons; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Superior Cervical Ganglion | 1999 |
Endothelin enhances adenosine and isoprenaline elevated cyclic AMP levels in rat cerebellar slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebellum; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Endothelin; Tritium | 1999 |
Sequential changes in autonomic regulation of cardiac myocytes after in vivo endotoxin injection in rat.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adenylyl Cyclases; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Calcium Channel Agonists; Calcium Channels, L-Type; Colforsin; Diterpenes; Electrophysiology; Endotoxemia; Endotoxins; Enzyme Activators; Escherichia coli; Heart; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Male; Myocardium; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Sepsis | 1999 |
Developmental changes in renal renin mRNA half-life and responses to stimulation in fetal lambs.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Fetus; Half-Life; Isoproterenol; Kidney; Kidney Cortex; Nucleic Acid Synthesis Inhibitors; Renin; RNA Stability; RNA, Messenger; Sheep; Transcription, Genetic | 1999 |
Agonist-induced sensitization of beta-adrenoceptor signaling in neonatal rat heart: expression and catalytic activity of adenylyl cyclase.
Topics: Adenylyl Cyclases; Age Factors; Animals; Animals, Newborn; Bromides; Colforsin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Male; Manganese; Oxidopamine; Protein Isoforms; Random Allocation; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Sympathectomy; Sympathomimetics; Transcription, Genetic | 1999 |
Canine cardiac muscarinic receptors, G proteins, and adenylate cyclase after long-term morphine.
Topics: Adenylyl Cyclases; Animals; Atrial Function; Carbachol; Colforsin; Dogs; Drug Interactions; Epinephrine; GTP-Binding Proteins; Heart; Heart Atria; Heart Ventricles; Isoproterenol; Morphine; Norepinephrine; Receptors, Muscarinic; Time Factors; Ventricular Function | 1999 |
Characterization of positive inotropic effect of colforsin daropate [correction of dapropate] hydrochloride, a water-soluble forskolin derivative, in isolated adult rat cardiomyocytes.
Topics: Animals; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Rats; Rats, Sprague-Dawley | 1999 |
Development of human and rabbit vaginal smooth muscle cell cultures: effects of vasoactive agents on intracellular levels of cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Alprostadil; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Female; Humans; Isoproterenol; Muscle, Smooth; Nitroprusside; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Piperazines; Purines; Rabbits; Sildenafil Citrate; Sulfones; Vagina; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Effect of adrenoreceptors on endotoxin-induced cytokines and lipid peroxidation in lung explants.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Chemokine CXCL2; Colforsin; Culture Techniques; Cyclic AMP; Cytokines; Enzyme Activators; Interleukin-10; Isoproterenol; Lipid Peroxidation; Lipopolysaccharides; Lung; Male; Monokines; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Tumor Necrosis Factor-alpha | 1999 |
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Osmotic Pressure; Pinacidil; Rats; Rats, Sprague-Dawley; Sucrose; Vasodilator Agents | 1999 |
Activation of protein kinase A increases phospholipase D activity and inhibits phospholipase D activation by acetylcholine in tracheal smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Chromatography, Thin Layer; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Muscle, Smooth; Palmitic Acid; Phospholipase D; Proteins; Swine; Trachea | 1999 |
Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cell Line; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Indoles; Isoenzymes; Isoproterenol; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current.
Topics: Animals; Calcium Channels; Captopril; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Heart; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Isoproterenol; Nephrectomy; Patch-Clamp Techniques; Rabbits; Random Allocation; Receptors, Adrenergic, beta; Renal Artery; Time Factors | 2000 |
Ketamine inhibits agonist-induced cAMP accumulation increase in human airway smooth muscle cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthetics, Dissociative; Cell Line; Colforsin; Cyclic AMP; Humans; Isoproterenol; Ketamine; Muscle, Smooth; Trachea | 1999 |
Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril.
Topics: Adenylyl Cyclases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley | 1999 |
Myocardial beta-adrenoceptor down-regulation by norepinephrine is linked to reduced norepinephrine uptake activity.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Colforsin; Dobutamine; Dogs; Down-Regulation; Enzyme Activation; Guanylyl Imidodiphosphate; Heart Ventricles; Hemodynamics; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Myocardial Contraction; Norepinephrine; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Ventricular Function | 1999 |
Cyclic AMP regulates G(omicronalpha) protein and mRNA levels by modulating the transcriptional rate of G(omicronalpha) gene.
Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Kinetics; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1999 |
Transregulation of adenylyl-cyclase-coupled inhibitory receptors in heart failure enhances anti-adrenergic effects on adult rat cardiomyocytes.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Calcium Chloride; Carbachol; Cell Size; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Heart Failure; Isoproterenol; Male; Microscopy, Polarization; Muscarinic Agonists; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P1; Regression Analysis | 1999 |
A genetically encoded, fluorescent indicator for cyclic AMP in living cells.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; beta-Lactamases; Bucladesine; CHO Cells; Colforsin; COS Cells; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytogenetic Analysis; Gene Expression Regulation, Enzymologic; Genes, Reporter; Green Fluorescent Proteins; Humans; Indicators and Reagents; Isoproterenol; Kidney; Luminescent Proteins; Microscopy, Fluorescence; Mutagenesis; Norepinephrine; Propranolol; Second Messenger Systems; Transfection | 2000 |
The effects of gadolinium, a stretch-sensitive channel blocker, on diaphragm muscle.
Topics: Action Potentials; Adenosine Monophosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Colforsin; Cricetinae; Culture Techniques; Diaphragm; Dose-Response Relationship, Drug; Enzyme Activation; Evoked Potentials; Gadolinium; Ion Channels; Isometric Contraction; Isoproterenol; Mesocricetus; Muscle Fibers, Skeletal; Nifedipine; Patch-Clamp Techniques | 1999 |
Gi/Go couple met-enkephalin to inhibition of cholinergic and beta-adrenergic stimulation of lacrimal secretion.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP; Enkephalin, Methionine; Eye Proteins; GTP-Binding Proteins; Isoproterenol; Lacrimal Apparatus; Male; Rabbits; Vasoactive Intestinal Peptide | 2000 |
Milrinone, a phosphodiesterase III inhibitor, antagonizes the neuromuscular blocking effect of a non-depolarizing muscle relaxant in vitro.
Topics: Adrenergic beta-Agonists; Aminophylline; Animals; Colforsin; Diaphragm; Drug Interactions; Electric Stimulation; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth; Neuromuscular Nondepolarizing Agents; Phosphodiesterase Inhibitors; Phrenic Nerve; Rats; Rats, Wistar | 1999 |
Stimulation of Cl(-) secretion by chlorzoxazone.
Topics: Amiloride; Anions; Bronchi; Bumetanide; Cell Membrane; Cells, Cultured; Charybdotoxin; Chlorine; Chlorzoxazone; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Interactions; Epithelium; Glyburide; Humans; Isoproterenol; Nasal Mucosa; Nystatin; Potassium Channel Blockers; Rubidium; Zoxazolamine | 2000 |
Bradykinin regulates captopril-induced upregulation of beta-adrenergic receptor in cultured neonatal rat cardiomyocytes.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Captopril; Cells, Cultured; Colforsin; Culture Media; Female; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Adrenergic, beta; Receptors, Bradykinin; Up-Regulation | 2000 |
Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus.
Topics: Adenine; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic AMP; Dexamethasone; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Isoproterenol; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Nitroprusside; Pinacidil; Tetrodotoxin; Thionucleotides; Vasoactive Intestinal Peptide | 2000 |
Effects of cortisol and growth hormone on lipolysis in human adipose tissue.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Aged; Bucladesine; Colforsin; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Female; Growth Hormone; Humans; Hydrocortisone; Isoproterenol; Lipolysis; Male; Middle Aged; Norepinephrine | 2000 |
Changes in adenylyl cyclase isoforms as a mechanism for thyroid hormone modulation of cardiac beta-adrenergic receptor responsiveness.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Northern; Colforsin; Guanylyl Imidodiphosphate; Heart; Hyperthyroidism; Hypothyroidism; Isoenzymes; Isoproterenol; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Thyroid Hormones | 2000 |
Nitric oxide-dependent vasodilatation of rabbit femoral artery by beta(2)-adrenergic stimulation or cyclic AMP elevation in vivo.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Bucladesine; Colforsin; Cyclic AMP; Enzyme Inhibitors; Femoral Artery; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Propanolamines; Rabbits; Vasodilation | 2000 |
Evidence for different interactions between beta(1)- and beta(2)-adrenoceptor subtypes with adenylyl cyclase in the rat brain: a concentration-response study using forskolin.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Algorithms; Animals; Antidepressive Agents, Tricyclic; Brain; Brain Chemistry; Cerebral Cortex; Colforsin; Cyclic AMP; Desipramine; In Vitro Techniques; Isoproterenol; Male; Models, Theoretical; Peripheral Nervous System; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction | 2000 |
Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Delayed Rectifier Potassium Channels; Egtazic Acid; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Hypnotics and Sedatives; Intracellular Fluid; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Thiopental | 2000 |
Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart.
Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Alprostadil; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; CHO Cells; Colforsin; Coronary Vessels; Creatine Kinase; Cricetinae; Cricetulus; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Ventricles; Hemodynamics; Infusions, Intra-Arterial; Isoenzymes; Isoproterenol; Male; Muscle Proteins; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Second Messenger Systems; Staining and Labeling; Swine; Swine, Miniature; Transfection | 2000 |
Different activity of adenylyl cyclase in prefrontal cortex in three rat strains. The effect of amphetamine.
Topics: Adenylyl Cyclases; Amphetamine; Animals; Colforsin; Guanylyl Imidodiphosphate; Isoproterenol; Male; Prefrontal Cortex; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar | 1998 |
Beta-3 adrenergic stimulation of L-type Ca(2+) channels in rat portal vein myocytes.
Topics: 1-Propanol; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Barium; Calcium Channels, L-Type; Cells, Cultured; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Isoquinolines; Membrane Potentials; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Portal Vein; Propanolamines; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides | 2000 |
Influence of heredity for obesity on adipocyte lipolysis in lean and obese subjects.
Topics: Adipocytes; Adult; Blood Glucose; Blood Pressure; Body Mass Index; Bucladesine; Cholesterol, HDL; Colforsin; Female; Glycerol; Humans; Insulin; Isoproterenol; Lipolysis; Male; Middle Aged; Obesity | 2000 |
beta-adrenoceptor-stimulated lipolysis of subcutaneous abdominal adipocytes as a determinant of fat oxidation in obese men.
Topics: Abdomen; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Bucladesine; Cells, Cultured; Colforsin; Humans; Isoproterenol; Lipolysis; Male; Middle Aged; Obesity; Oxygen Consumption; Regression Analysis; Skin; Theophylline; White People | 2000 |
Ontogeny of G-protein expression: control by beta-adrenoceptors.
Topics: Adrenergic beta-Agonists; Aging; Animals; Colforsin; Drug Tolerance; Female; Fluorides; Gene Expression Regulation, Developmental; GTP-Binding Proteins; Heart; Immunohistochemistry; Isoproterenol; Magnesium; Male; Myocardium; Oxidopamine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sympathetic Fibers, Postganglionic; Sympatholytics | 2000 |
Modulation of G-protein linked cAMP accumulation in immortalized murine cortical astrocytes by retroviral infection.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Biological Transport; Cell Line, Transformed; Colforsin; Cyclic AMP; GTP-Binding Proteins; Isoproterenol; Leukemia, Experimental; Mice; Moloney murine leukemia virus; Neocortex; Propranolol; Receptors, Adrenergic, beta; Retroviridae Infections; Tumor Virus Infections | 2000 |
Hydrogen peroxide generation by monoamine oxidases in rat white adipocytes: role on cAMP production.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Carbon Radioisotopes; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; Hydrogen Peroxide; Isoproterenol; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Rats; Rats, Wistar; Semicarbazides; Tyramine | 2000 |
The effects of agonist stimulation and beta(2)-adrenergic receptor level on cellular distribution of gs(alpha) protein.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; CHO Cells; Cholera Toxin; Colforsin; Cricetinae; GTP-Binding Protein alpha Subunits, Gs; Humans; Isoproterenol; Microscopy, Confocal; Receptors, Adrenergic, beta-2; Signal Transduction; Transfection | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; Gastric Emptying; Gastric Fundus; Gastric Mucosa; Hypertension; Isoproterenol; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2000 |
K+ secretion in strial marginal cells is stimulated via beta 1-adrenergic receptors but not via beta 2-adrenergic or vasopressin receptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Deamino Arginine Vasopressin; Epinephrine; Gerbillinae; Humans; Isoproterenol; Mice; Norepinephrine; Potassium; Propranolol; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Vasopressin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stria Vascularis | 2000 |
Rapid electrical stimulation of contraction reduces the density of beta-adrenergic receptors and responsiveness of cultured neonatal rat cardiomyocytes. Possible involvement of microtubule disassembly secondary to mechanical stress.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Cells, Cultured; Colforsin; Diacetyl; Dihydroalprenolol; Down-Regulation; Electric Stimulation; Enzyme Inhibitors; Heart Failure; Isoproterenol; Microtubules; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Pacemaker, Artificial; Paclitaxel; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stress, Mechanical; Tritium; Vasodilator Agents | 2000 |
Endoplasmic reticulum contribution to the relaxant effect of cGMP- and cAMP-elevating agents in feline aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Calcium-Binding Proteins; Cats; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endoplasmic Reticulum; Enzyme Activation; In Vitro Techniques; Isoproterenol; Nitroprusside; Phosphorylation; Vasodilation | 2000 |
Exercise training restores adenosine-induced relaxation in coronary arteries distal to chronic occlusion.
Topics: Adenosine; Animals; Arteries; Calcium; Chronic Disease; Colforsin; Coronary Disease; Coronary Vessels; Female; In Vitro Techniques; Isoproterenol; Nitroprusside; Osmolar Concentration; Physical Conditioning, Animal; Swine; Swine, Miniature; Vasodilation; Vasodilator Agents | 2000 |
Voltage-dependent calcium channels in ventricular cells of rainbow trout: effect of temperature changes in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Animals; Barium; Body Temperature; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotonic Agents; Cold Temperature; Colforsin; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nifedipine; Oncorhynchus mykiss; Patch-Clamp Techniques; Pyrroles; Tetrodotoxin | 2000 |
Characterization of ep prostanoid receptor subtypes in primary cultures of bovine ciliary epithelial cells by immunofluorescent microscopy and functional studies.
Topics: Animals; Cattle; Cells, Cultured; Ciliary Body; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Inositol Phosphates; Isoproterenol; Microscopy, Fluorescence; Pigment Epithelium of Eye; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Glycogen synthase association with the striated muscle glycogen-targeting subunit of protein phosphatase-1. Synthase activation involves scaffolding regulated by beta-adrenergic signaling.
Topics: Adrenergic beta-Agonists; Amino Acid Substitution; Animals; Binding Sites; Colforsin; COS Cells; Enzyme Activation; Enzyme Inhibitors; Glycogen; Glycogen Synthase; Isoproterenol; Isoquinolines; Muscle, Skeletal; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Phosphatase 1; Rabbits; Signal Transduction; Structure-Activity Relationship; Sulfonamides | 2000 |
Potassium augments vascular relaxation mediated by nitric oxide in the carotid arteries of hypertensive Dahl rats.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Carotid Arteries; Colforsin; Dietary Supplements; Enzyme Inhibitors; Hypertension; Isoproterenol; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Nitroprusside; Penicillamine; Potassium, Dietary; Rats; Rats, Inbred Dahl; S-Nitroso-N-Acetylpenicillamine; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasodilation; Vasodilator Agents | 2000 |
Regulation of coronary myoplasmic Ca(2+)-myosin light chain phosphorylation pathway and vasomotor tone: hyperpolarizing versus depolarizing cardioplegia.
Topics: Animals; Arterioles; Calcium; Cardioplegic Solutions; Colforsin; Coronary Vessels; Heart Arrest, Induced; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Magnesium; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phosphorylation; Pinacidil; Potassium; Rats; Rats, Sprague-Dawley | 2000 |
Inhibition by SR 59119A of isoprenaline-, forskolin- and VIP-induced relaxation of human isolated bronchi.
Topics: Adenosine Monophosphate; Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Bronchi; Colforsin; Ethanolamines; Humans; In Vitro Techniques; Interleukin-1; Isoproterenol; Middle Aged; Pertussis Toxin; Receptors, Adrenergic, beta; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 2000 |
Short-term effects of postnatal manipulation on central beta-adrenoceptor transmission.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Animals; Animals, Suckling; Cerebellum; Cerebral Cortex; Colforsin; Corticosterone; Cyclic AMP; Emotions; Female; Handling, Psychological; Hippocampus; Isoproterenol; Male; Norepinephrine; Pregnancy; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Restraint, Physical; Signal Transduction; Stress, Physiological; Tritium | 1999 |
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Pyrroles; Rats; Receptors, Adrenergic, beta; Urinary Bladder; Virulence Factors, Bordetella | 2000 |
Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation.
Topics: Amygdala; Animals; Auditory Cortex; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Indoles; Isoproterenol; Long-Term Potentiation; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Thalamus; Transcription, Genetic | 2000 |
Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Autonomic Nervous System; Carbachol; Cardiotonic Agents; Colforsin; Heart Conduction System; Isoproterenol; Manganese; Myocardium; Nicotine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Adrenergic, beta; Receptors, Muscarinic | 2000 |
Differentiation of cultured brown adipocytes is associated with a selective increase in the short variant of g(s)alpha protein. Evidence for higher functional activity of g(s)alphaS.
Topics: Adenylyl Cyclases; Adipocytes; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Brain Chemistry; Cell Differentiation; Cell Division; Cell Fractionation; Cell Membrane; Cells, Cultured; Colforsin; Electrophoresis, Polyacrylamide Gel; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guinea Pigs; Isoproterenol; Manganese; Mice; Myocardium; Rats | 2000 |
Volume overload cardiac hypertrophy exhibits decreased expression of g(s)alpha and not of g(i)alpha in heart.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Arteriovenous Shunt, Surgical; Blood Pressure; Blotting, Northern; Body Weight; Cardiomegaly; Colforsin; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Myocardium; Organ Size; Protein Isoforms; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Fluoride | 2000 |
Identification of functional somatostatin receptors and G-proteins in a new line of human foetal lung fibroblasts.
Topics: Adenylyl Cyclases; Cell Line; Colforsin; DNA, Complementary; Embryo, Mammalian; Fibroblasts; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lung; Receptors, Somatostatin; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
beta-adrenergic receptor-mediated presynaptic facilitation of inhibitory GABAergic transmission at cerebellar interneuron-Purkinje cell synapses.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Cerebellum; Colforsin; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoproterenol; Neural Inhibition; Norepinephrine; Presynaptic Terminals; Protein Isoforms; Purkinje Cells; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Synapses; Synaptic Transmission | 2000 |
Impaired G(s)alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts.
Topics: Adenylyl Cyclases; Animals; Calcium; Cardiotonic Agents; Cholera Toxin; Chronic Disease; Colforsin; Cyclic AMP; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gs; Heart Ventricles; Hypoxia; Intracellular Membranes; Isoproterenol; Male; Myocardium; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reference Values; Sodium Fluoride | 2000 |
Establishment and characterization of steroidogenic granulosa cells expressing beta(2)-adrenergic receptor: regulation of adrenodoxin and steroidogenic acute regulatory protein by adrenergic agents.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenodoxin; Animals; Blotting, Western; Cell Line, Transformed; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Follicle Stimulating Hormone; Genes, ras; Granulosa Cells; Immunohistochemistry; Isoproterenol; Metoprolol; Phosphodiesterase Inhibitors; Phosphoproteins; Plasmids; Progesterone; Propranolol; Rats; Receptors, Adrenergic, beta-2; Simian virus 40; Transfection | 2000 |
Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity.
Topics: Adenoviridae; Adenylyl Cyclases; Animals; Cardiac Output; Colforsin; Coronary Vessels; Gene Transfer Techniques; Genetic Vectors; Injections, Intra-Arterial; Isoproterenol; Recombinant Proteins; Swine; Ventricular Function, Left | 2000 |
Ischemic inactivation of G protein-coupled receptor kinase and altered desensitization of canine cardiac beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 5; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Protein Serine-Threonine Kinases; Radioligand Assay; Receptors, Adrenergic, beta; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2000 |
ATP and beta-adrenergic stimulation enhance voltage-gated K current inactivation in brown adipocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Adipocytes; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Arachidonic Acid; Colforsin; Cyclic AMP; Fatty Acids; Ion Channel Gating; Isoproterenol; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Signal Transduction; Stimulation, Chemical | 2000 |
Phosphorylation of protein phosphatase-1 inhibitors, inhibitor-1 and DARPP-32, in renal medulla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Benzazepines; Calcimycin; Carrier Proteins; Colforsin; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Ionophores; Isoproterenol; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; RNA-Binding Proteins | 2000 |
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thoracic; Bucladesine; Colforsin; Cyclic AMP; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Inbred F344; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 2000 |
beta-agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Isoproterenol; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Propranolol; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sirolimus; Sodium-Potassium-Exchanging ATPase | 2000 |
Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Chronic Disease; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Heart Rate; Heart Ventricles; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Hypoxia; Isoproterenol; Male; Myocardium; Norepinephrine; Pertussis Toxin; Propanolamines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride; Sympathomimetics; Tritium; Virulence Factors, Bordetella; Weight Gain | 2001 |
Simultaneous measurements of intracellular cAMP and L-type Ca2+ current in single frog ventricular myocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Cytosol; Fluorescent Dyes; GTP-Binding Proteins; Heart Ventricles; Isoproterenol; Membrane Potentials; Myocardial Contraction; Myocardium; Patch-Clamp Techniques; Rana esculenta | 2001 |
The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carotid Artery, Common; Colforsin; Endothelium, Vascular; Enzyme Inhibitors; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Adrenergic, beta; Receptors, Muscarinic; Vasoconstrictor Agents; Vasodilation | 2000 |
Age-related differences in messenger ribonucleic acid expression of key proteins involved in adipose cell differentiation and metabolism.
Topics: Abdomen; Adipocytes; Adipose Tissue; Adult; Aging; Bucladesine; Canada; Cell Differentiation; Colforsin; Complement C3; France; Gene Expression Regulation, Developmental; Humans; Isoproterenol; Lipolysis; Lipoprotein Lipase; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sterol Esterase; Theophylline; Transcription Factors; Transcription, Genetic; White People | 2001 |
Relationships between lipolysis induced by various lipolytic agents and hormone-sensitive lipase in rat fat cells.
Topics: Adipocytes; Animals; Biological Transport; Bucladesine; Cells, Cultured; Colforsin; Isoproterenol; Kinetics; Lipolysis; Male; Norepinephrine; Rats; Rats, Wistar; Sterol Esterase; Sympathomimetics | 2001 |
Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aorta; Aurora Kinases; Blood Pressure; Carotid Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; Heart Failure; In Vitro Techniques; Isoproterenol; Ligation; Muscle, Smooth, Vascular; Myocardial Infarction; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Ventricular Pressure | 2001 |
The influence of beta-adrenergic activation on noradrenergic alpha1 activation of rabbit afferent arterioles.
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Arterioles; Calcium; Colforsin; Cyclic AMP; Cytosol; Enzyme Activation; Fluorescent Dyes; Fura-2; Isoproterenol; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 2000 |
Impaired beta-adrenergic hyperpolarization in arteries from prehypertensive spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Cholera Toxin; Colforsin; Cromakalim; Hypertension; Isoproterenol; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vascular Resistance | 2001 |
Species- and temperature-dependency of the decrease in myofilament Ca2+ sensitivity induced by beta-adrenergic stimulation.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Species Specificity; Temperature | 2001 |
Effects of verapamil and elgodipine on isoprenaline-induced metabolic responses in rabbits.
Topics: Adipose Tissue; Animals; Blood Glucose; Brimonidine Tartrate; Calcium Channel Blockers; Colforsin; Consciousness; Dihydropyridines; Dose-Response Relationship, Drug; Epinephrine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Isoproterenol; Male; Metabolism; Potassium; Quinoxalines; Rabbits; Verapamil | 2001 |
I(f) current and spontaneous activity in mouse embryonic ventricular myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Brain; Cells, Cultured; Colforsin; Female; Gene Expression Regulation, Developmental; Heart Ventricles; Ion Channels; Isoproterenol; Membrane Potentials; Mice; Myocardium; Pregnancy; RNA, Messenger; Time Factors; Ventricular Function | 2001 |
Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Apoptosis; Arginine; Astrocytes; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Energy Metabolism; Enzyme Activation; Gene Products, tat; GTP-Binding Protein alpha Subunits, Gi-Go; HIV-1; Hydrazines; Isoproterenol; Lipopolysaccharides; Microglia; Nerve Degeneration; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Peptides; Pertussis Toxin; Rats; Rats, Wistar; Recombinant Fusion Proteins; Second Messenger Systems; tat Gene Products, Human Immunodeficiency Virus; Tosylphenylalanyl Chloromethyl Ketone; Virulence Factors, Bordetella | 2001 |
Endogenous cyclic AMP-adenosine pathway regulates cardiac fibroblast growth.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cell Division; Colforsin; Cyclic AMP; DNA; Fibroblasts; Isoproterenol; Male; Myocardium; Norepinephrine; Protein Biosynthesis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2001 |
Cell-specific properties of type V and type IX adenylyl cyclase isozymes in 293T cells and embryonic chick ventricular myocytes.
Topics: Adenoviridae; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Genetic Vectors; Heart Ventricles; Humans; Isoenzymes; Isoproterenol; Kidney; Molecular Sequence Data; Myocardium; Organ Specificity; Plasmids; Receptors, Adrenergic, beta; Transfection | 2001 |
Diabetes reduces right atrial beta-adrenergic signaling but not agonist stimulation of heart rate in swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Heart Atria; Heart Rate; Isoproterenol; Receptors, Adrenergic, beta; Signal Transduction; Swine; Swine, Miniature | 2001 |
cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adrenomedullin; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Coronary Vessels; Culture Techniques; Cyclic AMP; Dogs; Endothelium, Vascular; Isoproterenol; Nitric Oxide; Peptides; Signal Transduction | 2001 |
Heterologous sensitization of recombinant adenylate cyclases by activation of D(2) dopamine receptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Cell Line; Colforsin; Cyclic AMP; Dopamine Agonists; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Humans; Ionophores; Isoenzymes; Isoproterenol; Kidney; Quinpirole; Receptors, Dopamine D2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2001 |
Hypoxia alters the sensitivity of the L-type Ca(2+) channel to alpha-adrenergic receptor stimulation in the presence of beta-adrenergic receptor stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channels, L-Type; Cell Hypoxia; Cell Separation; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Isoproterenol; Membrane Potentials; Methoxamine; Myocardium; Norepinephrine; Patch-Clamp Techniques; Phospholipases A; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 2001 |
Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes.
Topics: Animals; Annexin A7; Caffeine; Calcium; Cardiotonic Agents; Central Nervous System Stimulants; Colforsin; Embryo, Mammalian; Female; Gene Targeting; Glucose; Homeostasis; Hypoglycemic Agents; Immunoblotting; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Myocardium; Patch-Clamp Techniques; Tolbutamide | 2001 |
Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amphotericin B; Analysis of Variance; Animals; Arrhythmias, Cardiac; Cardiomegaly; Colforsin; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Isoproterenol; Male; Membrane Potentials; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; omega-N-Methylarginine; Oxadiazoles; Patch-Clamp Techniques; Penicillamine; Pyridines; Rats; Rats, Inbred SHR; Sinoatrial Node | 2001 |
Hypoxic vasodilation in porcine coronary artery is preferentially inhibited by organ culture.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchodilator Agents; Calcium; Cell Hypoxia; Colforsin; Coronary Vessels; Cycloheximide; Dose-Response Relationship, Drug; Isoproterenol; Nitrogen; Nitroprusside; Organ Culture Techniques; Oxygen; Potassium Chloride; Protein Synthesis Inhibitors; Swine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Genetic correlations between initial sensitivity to Ethanol and brain cAMP signaling in inbred and selectively bred mice.
Topics: Animals; Brain; Cerebellum; Colforsin; Cyclic AMP; Ethanol; Genotype; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Signal Transduction; Species Specificity | 2001 |
Ca(2+)-dependent sensitization of adenylyl cyclase activity.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding, Competitive; Calcimycin; Calcium; Cell Line; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Ionophores; Isoenzymes; Isoproterenol; Receptors, Adrenergic, beta-2 | 2001 |
Isoproterenol inhibits resistin gene expression through a G(S)-protein-coupled pathway in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Dexamethasone; Drug Interactions; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Hormones, Ectopic; Intercellular Signaling Peptides and Proteins; Isoproterenol; Mice; Molecular Mimicry; Nerve Growth Factor; Propranolol; Proteins; Resistin; RNA, Messenger; Triiodothyronine | 2001 |
Modulation of protein kinase A activation by fibronectin matrix proteins at developing neuromuscular synapses in Xenopus laevis cell cultures.
Topics: Acetylcholine; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activation; Extracellular Matrix; Fibronectins; Isoproterenol; Nerve Growth Factors; Sympathomimetics; Synapses; Synaptic Transmission; Xenopus laevis | 2001 |
Inhibitory effect of endothelin-1 on the isoproterenol-induced chloride current in human cardiac myocytes.
Topics: Adrenergic beta-Agonists; Adult; Aged; Atrial Function; Chloride Channels; Chlorides; Colforsin; Endothelin-1; Female; Heart Atria; Heart Ventricles; Humans; Isoproterenol; Male; Membrane Potentials; Middle Aged; Time Factors; Ventricular Function | 2001 |
Modulation of voltage-dependent calcium currents by serotonin in acutely isolated rat amygdala neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclases; Amygdala; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Enzyme Inhibitors; Ethylmaleimide; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Neurons; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Pertussis Toxin; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sympathomimetics; Thionucleotides; Virulence Factors, Bordetella | 2001 |
cAmp modulates exocytotic kinetics and increases quantal size in chromaffin cells.
Topics: Animals; Cattle; Cells, Cultured; Chromaffin Cells; Chromaffin Granules; Colforsin; Cyclic AMP; Exocytosis; Isoproterenol; Kinetics; Molecular Mimicry; Neuropeptides; Nitric Oxide; Pituitary Adenylate Cyclase-Activating Polypeptide; Synapses; Vasodilator Agents | 2001 |
Cyclic AMP-dependent protein kinase phosphorylates group III metabotropic glutamate receptors and inhibits their function as presynaptic receptors.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Cell Fractionation; Cerebellum; Colforsin; Cyclic AMP-Dependent Protein Kinases; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Propionates; Protein Structure, Tertiary; Rats; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Synapses | 2001 |
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
[(Dihydroindenyl)oxy]alkonic acid inhibits the cystic fibrosis transmembrane conductance regulator.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carboxylic Acids; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Glycolates; Humans; Indenes; Isoproterenol; Membrane Potentials; Nitrobenzoates; Time Factors; Tumor Cells, Cultured | 2001 |
Modulation of adipocyte G-protein expression in cancer cachexia by a lipid-mobilizing factor (LMF).
Topics: Adenylyl Cyclases; Adipocytes; Animals; Appetite Depressants; Cachexia; Cell Membrane; Colforsin; Eicosapentaenoic Acid; GTP-Binding Proteins; Isoproterenol; Male; Mice; Neoplasm Proteins; Neoplasms; Peptides; Weight Loss | 2001 |
Regulation of slowly activating potassium current (I(Ks)) by secretin in rat pancreatic acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Signaling; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gastrointestinal Agents; Isoproterenol; Isoquinolines; Membrane Potentials; Pancreas; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Rats; Secretin; Sulfonamides; Vasoactive Intestinal Peptide | 2001 |
cGMP-mediated inhibition of cardiac L-type Ca(2+) current by a monoclonal antibody against the M(2) ACh receptor.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Autoantibodies; Calcium Channels, L-Type; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanosine; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Oxadiazoles; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Modulation of glucagon receptor expression and response in transfected human embryonic kidney cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Colforsin; Cyclic AMP; Dactinomycin; Enzyme Inhibitors; Gene Expression; Glucagon; GTP-Binding Proteins; Humans; Isoproterenol; Kidney; Protein Synthesis Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Sympathomimetics; Transfection | 2001 |
Activation and inactivation of cAMP-response element-mediated gene transcription in cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cantharidin; Cardiotonic Agents; Cell Cycle Proteins; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanolamines; Gene Expression; Heart Failure; Isoproterenol; Luciferases; Myocardium; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Propane; Stimulation, Chemical; Time Factors; Transcription, Genetic | 2001 |
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Lysophosphatidylcholines; Male; Maleimides; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Adrenergic, beta; rho GTP-Binding Proteins; Spectrometry, Fluorescence; Theophylline; Trachea; Virulence Factors, Bordetella | 2001 |
Prostaglandin E(2) inhibits fibroblast chemotaxis.
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bucladesine; Cattle; Cell Line; Chemotactic Factors; Chemotaxis; Colforsin; Culture Media, Conditioned; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Fetus; Fibroblasts; Fibronectins; Humans; Indomethacin; Isoproterenol; Oxytocics; Respiratory Mucosa; Substance P; Vasoactive Intestinal Peptide; Vasodilator Agents | 2001 |
Bcl-2 protects lymphoma cells from apoptosis but not growth arrest promoted by cAMP and dexamethasone.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Annexin A5; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Count; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Gene Expression Regulation; Genes, bcl-1; Humans; Isoproterenol; Lymphoma; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2001 |
Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Mice; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Parotid Gland; Phosphoric Diester Hydrolases; Quinoxalines; Thapsigargin; Triazoles | 2001 |
Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Androstadienes; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Humans; Insulin; Isoproterenol; Lipolysis; Phosphodiesterase Inhibitors; Phosphorylation; Potassium Chloride; Quinolones; Sterol Esterase; Wortmannin; Xanthines | 2001 |
Synergistic interaction of diazepam with 3',5'-cyclic adenosine monophosphate-elevating agents on rat aortic rings.
Topics: Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Milrinone; Muscle Relaxants, Central; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Altered cellular calcium regulatory systems in a rat model of cirrhotic cardiomyopathy.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cardiomyopathies; Colforsin; Isoproterenol; Liver Cirrhosis, Experimental; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2001 |
Direct actions of adrenergic agents on rat anterior pituitary cells.
Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Animals; Calcium; Cells, Cultured; Clonidine; Colforsin; Corticotropin-Releasing Hormone; Culture Media; Epinephrine; Follicle Stimulating Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Isoproterenol; Luteinizing Hormone; Male; Phenylephrine; Pituitary Gland, Anterior; Prazosin; Prolactin; Propranolol; Rats; Thyrotropin | 2001 |
Regulation of human beta(1)-adrenergic receptors and their mRNA in neuroepithelioma SK-N-MC cells: effects of agonist, forskolin, and protein kinase A.
Topics: Adrenergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Isoproterenol; Isoquinolines; Receptors, Adrenergic, beta-1; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured | 2001 |
Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline.
Topics: Animals; Animals, Newborn; Body Weight; Clonidine; Colforsin; Down-Regulation; Female; GTP-Binding Proteins; Heart; Isoproterenol; Liver; Male; Membrane Proteins; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Sodium Fluoride; Terbutaline | 2001 |
Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling.
Topics: Adenylyl Cyclases; Adipocytes; Animals; Animals, Newborn; Blotting, Western; Catecholamines; Colforsin; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Obesity; Rats; Rats, Zucker; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2001 |
Second messengers regulate RGS2 expression which is targeted to the nucleus.
Topics: Astrocytoma; Blotting, Western; Carbachol; Cell Membrane; Cell Nucleus; Colforsin; Cyclic AMP; Cytosol; Humans; Immunohistochemistry; Isoproterenol; Microscopy, Confocal; Receptors, Adrenergic, beta; Receptors, Muscarinic; RGS Proteins; RNA, Messenger; Second Messenger Systems; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
Effects of oxidized low density lipoprotein on nitric oxide synthetase and protein kinase C activities in bovine endothelial cells.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Isoproterenol; Lipoproteins, LDL; Nitric Oxide Synthase; Oxidation-Reduction; Protein Kinase C; Serotonin | 2001 |
Impaired parasympathetic heart rate control in mice with a reduction of functional G protein betagamma-subunits.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiotonic Agents; Cell Membrane; Colforsin; Consciousness; Cyclic AMP; Cytosol; Electrocardiography; Electrophysiology; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Heart Rate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; Mice; Mice, Transgenic; Parasympathetic Nervous System; Propranolol; Sinoatrial Node; Transgenes; Vagus Nerve; Vasodilator Agents | 2002 |
Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells.
Topics: Adrenal Medulla; Animals; Cell Culture Techniques; Colforsin; Endothelium; Extracellular Matrix; Extracellular Matrix Proteins; Isoproterenol; Matrix Metalloproteinase 2; Rats; Second Messenger Systems | 2001 |
Rapid component I(Kr) of the guinea-pig cardiac delayed rectifier K(+) current is inhibited by beta(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Indoles; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Xamoterol | 2002 |
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Failure; Homeostasis; Immunoblotting; Intracellular Fluid; Isoproterenol; Isoquinolines; Male; Myocardial Infarction; Myocardium; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides | 2002 |
PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Isoproterenol; Muscle, Smooth; Phosphorylation; Rabbits; Stomach; Sympathomimetics; Thionucleotides | 2002 |
Activation of cAMP-dependent protein kinase suppresses the presynaptic cannabinoid inhibition of glutamatergic transmission at corticostriatal synapses.
Topics: Adrenergic Agonists; Animals; Benzoxazines; Calcium; Calcium Channel Blockers; Cannabinoids; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Activators; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Isoproterenol; Male; Morpholines; Naphthalenes; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Glutamate; Receptors, Presynaptic; Serine; Synapses | 2002 |
Beta-adrenergic regulation of amiloride-sensitive lung sodium channels.
Topics: Adrenergic beta-Agonists; Amiloride; Animals; Antiporters; Calcium; Cells, Cultured; Chelating Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Diuretics; Egtazic Acid; Enzyme Inhibitors; Epithelial Cells; Extravascular Lung Water; Isoproterenol; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sodium; Sodium Channels; Sulfonamides; Terbutaline | 2002 |
A homogeneous high throughput nonradioactive method for measurement of functional activity of Gs-coupled receptors in membranes.
Topics: Adrenergic beta-Agonists; Animals; Automation; Biotechnology; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Inhibitory Concentration 50; Isoproterenol; Kinetics; Propranolol; Temperature; Time Factors; Vasoconstrictor Agents; Vasopressins | 2002 |
Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Colforsin; Dihydropyridines; Electrophysiology; Evoked Potentials; Guinea Pigs; Heart Ventricles; Isoproterenol; Nitrendipine; Patch-Clamp Techniques; Phosphorylation | 2001 |
Impaired intracellular signal transduction via cyclic AMP contributes to cerebral vasospasm in rats with subarachnoid hemorrhage.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Rats; Rats, Wistar; Second Messenger Systems; Signal Transduction; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2002 |
cAMP modulation of Ca(2+)-regulated exocytosis in ACh-stimulated antral mucous cells of guinea pig.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP; Dinitrophenols; Drug Synergism; Exocytosis; Gastric Mucins; Gastric Mucosa; Guinea Pigs; Hypoxia; Isoproterenol; Male; Microscopy, Video; Phosphodiesterase Inhibitors; Pyloric Antrum; Uncoupling Agents | 2002 |
Pregnancy alters adrenergic mechanisms in uterine arterioles of rats.
Topics: Animals; Arterioles; Atenolol; Colforsin; Female; Isoproterenol; Phenylephrine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Uterus | 2002 |
Attenuated "cross talk" between kappa-opioid receptors and beta-adrenoceptors in the heart of chronically hypoxic rats.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Signaling; Cardiomegaly; Cholera Toxin; Chronic Disease; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; GTP-Binding Protein alpha Subunits, Gs; Heart; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Adrenergic, beta; Receptors, Opioid, kappa | 2002 |
Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blotting, Western; Chromatography, Ion Exchange; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Lung; Phosphodiesterase Inhibitors; Rats; Rolipram; Time Factors | 2002 |
Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats.
Topics: Adrenergic beta-Agonists; Algorithms; Alprenolol; Animals; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Colforsin; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasoconstriction | 2002 |
Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Isoproterenol; Isoquinolines; Juxtaglomerular Apparatus; Membrane Potentials; Mice; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Renin; Tetrahydroisoquinolines; Thionucleotides | 2002 |
MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Dynamins; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Glutathione Transferase; GTP Phosphohydrolases; GTPase-Activating Proteins; Humans; Immunoblotting; Inhibitory Concentration 50; Isoproterenol; Isoquinolines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Precipitin Tests; Protein Binding; rap1 GTP-Binding Proteins; Rats; src-Family Kinases; Sulfonamides; Time Factors; Transcriptional Activation; Transfection | 2002 |
Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Induction; Fibroblasts; Guanylate Cyclase; Interleukin-1; Isoproterenol; Male; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley | 2002 |
Regulation of cardiac CFTR Cl(-) channel activity by a Mg(2+)-dependent protein phosphatase.
Topics: Adenosine Triphosphate; Animals; Anthracenes; Cardiotonic Agents; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Enzyme Inhibitors; Genistein; Guinea Pigs; Isoproterenol; Magnesium; Membrane Potentials; Myocytes, Cardiac; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Protein Phosphatase 2C | 2002 |
[Catecholamine levels in plasma and beta2-adrenoreceptor-dependent synthesis of cAMP in lymphocytes of patients with primary pulmonary hypertension].
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Blood Pressure; Catecholamines; Colforsin; Cyclic AMP; Epinephrine; Female; Humans; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Lymphocytes; Male; Middle Aged; Norepinephrine; Receptors, Adrenergic, beta-2 | 2002 |
cAMP signal transduction, a potential compensatory pathway for coronary endothelial NO production after heart failure.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adrenomedullin; Animals; Bradykinin; Cardiac Output, Low; Cardiotonic Agents; Cholinergic Agents; Colforsin; Coronary Vessels; Cyclic AMP; Dogs; Down-Regulation; Endothelium, Vascular; Isoproterenol; Nitric Oxide; Nitric Oxide Synthase; Peptides; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction | 2002 |
Regulation of cellular alpha-MSH and beta-endorphin during stimulated secretion from intermediate pituitary cells: involvement of aspartyl and cysteine proteases in the control of cellular levels of alpha-MSH and beta-endorphin.
Topics: alpha-MSH; Animals; Aspartic Acid Endopeptidases; beta-Endorphin; Colforsin; Cysteine Endopeptidases; Dopamine; Isoproterenol; Male; Pituitary Gland; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2002 |
Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice.
Topics: Adrenergic beta-Agonists; Animals; Ataxia; Blotting, Western; Brain Chemistry; Central Nervous System Depressants; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA, Complementary; Drug Tolerance; Ethanol; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Postural Balance; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2002 |
Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Cerebellum; Cerebral Cortex; Colforsin; Cyclic AMP; Female; Handling, Psychological; Hippocampus; Isoproterenol; Norepinephrine; Phosphodiesterase Inhibitors; Pregnancy; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction | 2002 |
Endothelin-stimulated glucose uptake: effects of intracellular Ca(2+), cAMP and glucosamine.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Animals, Newborn; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activators; Fibroblasts; Glucosamine; Glucose; Hexosamines; Insulin; Interleukin 1 Receptor Antagonist Protein; Isoproterenol; Mice; Myocardium; Rats; Sialoglycoproteins; Stimulation, Chemical | 2002 |
High plasma buffering and the absence of a red blood cell beta-NHE response in brown bullhead (Ameiurus nebulosus).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Buffers; Colforsin; Cyclic AMP; Erythrocytes; Female; Hydrogen-Ion Concentration; Ictaluridae; In Vitro Techniques; Isoproterenol; Male; Receptors, Adrenergic, beta; Sodium-Hydrogen Exchangers | 2002 |
Sex-dependent thermogenesis, differences in mitochondrial morphology and function, and adrenergic response in brown adipose tissue.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Body Weight; Bucladesine; Calorimetry, Indirect; Colforsin; DNA; Female; Isoproterenol; Light; Lipolysis; Male; Mitochondria; Norepinephrine; Organ Size; Oxygen Consumption; Propanolamines; Rats; Rats, Wistar; Respiratory Mechanics; Sex Characteristics; Thermogenesis; Triglycerides | 2002 |
Stable, sensitive, fluorescence-based method for detecting cAMP.
Topics: Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescence Polarization Immunoassay; Humans; Isoproterenol; Kidney; Quality Control; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Brain Chemistry; Colforsin; Female; GTP-Binding Proteins; Isoproterenol; Male; Nicotine; Nicotinic Agonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Signal Transduction; Substance Withdrawal Syndrome; Up-Regulation | 2002 |
Termination of immediate-early gene expression after stimulation by parathyroid hormone or isoproterenol.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; beta-Adrenergic Receptor Kinases; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; Gene Expression; Genes, Immediate-Early; Interleukin-6; Isoproterenol; Mice; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Receptors, Parathyroid Hormone; RNA, Messenger; Sympathomimetics; Tumor Cells, Cultured | 2002 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neoplasms; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2002 |
Effect of mild hypothermia on inodilator-induced vasodilation of pial arterioles in cats.
Topics: Administration, Topical; Amrinone; Animals; Arterioles; Body Temperature; Cardiotonic Agents; Cats; Colforsin; Dose-Response Relationship, Drug; Hemodynamics; Hypothermia, Induced; Isoproterenol; Pia Mater; Vasodilation; Vasodilator Agents | 2002 |
Efficient adenylyl cyclase activation by a beta2-adrenoceptor-G(i)alpha2 fusion protein.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Enzyme Activation; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Models, Biological; Proto-Oncogene Proteins; Receptors, Adrenergic, beta-2; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Recombinant Fusion Proteins; Spodoptera | 2002 |
Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cell Line; Cell Membrane; Colforsin; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Isoproterenol; NAD; Neuroblastoma; Pertussis Toxin; Phosphorus Radioisotopes; Tumor Cells, Cultured | 2002 |
NKCC activity restores muscle water during hyperosmotic challenge independent of insulin, ERK, and p38 MAPK.
Topics: Animals; Body Water; Colforsin; Culture Media; Cyclic AMP; Enzyme Inhibitors; Female; Glucose; Insulin; Intracellular Membranes; Isoproterenol; Mannitol; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Osmolar Concentration; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2003 |
Inhibition of cyclooxygenase-2: effects on renin secretion and expression in fetal lambs.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cells, Cultured; Colforsin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gene Expression Regulation, Developmental; Heart Rate; Isoenzymes; Isoproterenol; Kidney Cortex; Nitrobenzenes; Phosphodiesterase Inhibitors; Pregnancy; Prostaglandin-Endoperoxide Synthases; Renin; Renin-Angiotensin System; RNA, Messenger; Sheep, Domestic; Sulfonamides | 2003 |
Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Cardiovascular System; Colforsin; Coronary Circulation; Dobutamine; Dogs; Dopamine; Dopamine Agents; Female; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Solubility; Vasodilator Agents; Water | 2002 |
Involvement of cyclic AMP-mediated pathway in neural release of noradrenaline in canine isolated mesenteric artery and vein.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Autonomic Nervous System; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Edetic Acid; Electric Stimulation; Isoproterenol; Mesenteric Arteries; Mesenteric Veins; Milrinone; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Rolipram; Second Messenger Systems | 2003 |
Beta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Colforsin; Cyclic AMP; Heterotrimeric GTP-Binding Proteins; Insulin; Isoproterenol; Kinetics; Mice; Receptors, Adrenergic, beta-2; Signal Transduction | 2003 |
Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.
Topics: Acetylcholine; Animals; Aorta; Bronchodilator Agents; Cell Adhesion Molecules; Colforsin; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Microfilament Proteins; Nitroprusside; Nucleotides, Cyclic; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Serine; Vasodilation; Vasodilator Agents | 2003 |
Cl secretagogues reduce basolateral K permeability in the rabbit corneal epithelium.
Topics: Animals; Basement Membrane; Biological Transport, Active; Chlorine; Colforsin; Electric Conductivity; Electrophysiology; Epinephrine; Epithelium, Corneal; Female; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Microelectrodes; Ouabain; Permeability; Potassium; Rabbits; Rubidium; Sodium | 2002 |
Beta-adrenergic stimulation of Na(+)-K(+)-2Cl(-) cotransport activity in the rabbit lens.
Topics: Adrenergic beta-Agonists; Animals; Bumetanide; Colforsin; Culture Techniques; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Lens, Crystalline; Ouabain; Potassium; Rabbits; Sodium-Potassium-Chloride Symporters | 2003 |
Increased relaxant action of forskolin and isoproterenol against muscarinic agonist-induced contractions in smooth muscle from M2 receptor knockout mice.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Drug Combinations; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Receptor, Muscarinic M2; Receptors, Muscarinic | 2003 |
TNF-alpha rapidly antagonizes the beta-adrenergic responses of the chloride current in guinea-pig ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Chloride Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration; Patch-Clamp Techniques; Pertussis Toxin; Receptors, Adrenergic, beta; Tumor Necrosis Factor-alpha | 2003 |
Protein kinase A hyperphosphorylation increases basal current but decreases beta-adrenergic responsiveness of the sarcolemmal Na+-Ca2+ exchanger in failing pig myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Female; Heart Failure; Isoproterenol; Male; Membrane Potentials; Myocardium; Myocytes, Cardiac; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Adrenergic, beta; Sarcolemma; Sodium-Calcium Exchanger; Swine | 2003 |
Exposure to intermittent high altitude induces different changes in adenylyl cyclase activity in hearts of young and adult Wistar rats.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Altitude; Altitude Sickness; Animals; Colforsin; Enzyme Activation; Heart Ventricles; Hypoxia; Isoproterenol; Male; Myocardium; Organ Size; Rats; Rats, Wistar | 2003 |
Sphingosine modulation of cAMP levels and beating rate in rat heart.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Myocytes, Cardiac; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Sphingosine; Time Factors | 2002 |
Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Colforsin; Ethanolamines; Fatty Acids, Nonesterified; Female; Gestational Age; Glucose Tolerance Test; Glycerol; Insulin; Isoproterenol; Leptin; Lipids; Lipolysis; Lumbosacral Region; Organ Size; Pregnancy; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3 | 2003 |
Augmentation of rat urinary bladder relaxation mediated by beta1-adrenoceptors in experimental diabetes.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Urinary Bladder | 2003 |
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Colforsin; Fluorides; Gene Expression; GTP-Binding Proteins; Hypertrophy, Left Ventricular; Isoproterenol; Manganese; Myocardium; Pressure; Protein Isoforms; Rats; Rats, Wistar; Signal Transduction | 2003 |
Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiologic Techniques, Cardiac; Female; Heart Failure; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors | 2003 |
Modulation of cholinergic responsiveness through the [beta]-adrenoceptor signal transmission pathway in bovine trachealis.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Cholera Toxin; Colforsin; Electric Stimulation; Isoproterenol; Peptides; Receptors, Adrenergic, beta; Signal Transduction; Trachea | 2003 |
Interleukin (IL)-6 mRNA expression is stimulated by insulin, isoproterenol, tumour necrosis factor alpha, growth hormone, and IL-6 in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Enzyme Activation; Gene Expression; Growth Hormone; GTP-Binding Protein alpha Subunits, Gs; Insulin; Insulin Resistance; Interleukin-6; Isoproterenol; Kinetics; Mice; Receptors, Adrenergic, beta; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Postreceptor defects in alveolar epithelial beta-adrenergic signaling after prolonged isoproterenol infusion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Extravascular Lung Water; Isoproterenol; Male; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Respiratory Mucosa; Signal Transduction | 2003 |
Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells.
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Animals; Blood Glucose; Colforsin; Coronary Vessels; Cyclic AMP; Hyperglycemia; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth, Vascular; Peptides; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2003 |
Suppression of aquaporin adipose gene expression by isoproterenol, TNFalpha, and dexamethasone.
Topics: 3T3-L1 Cells; Animals; Aquaporins; Bucladesine; Cholera Toxin; Colforsin; Dexamethasone; Gene Expression; Isoproterenol; Mice; Propranolol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Cyclic AMP regulates aquaporin 5 expression at both transcriptional and post-transcriptional levels through a protein kinase A pathway.
Topics: Aquaporin 5; Aquaporins; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Isoproterenol; Membrane Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic | 2003 |
Inhibitory effects of interferon-gamma on the heterologous desensitization of beta-adrenoceptors by transforming growth factor-beta 1 in tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Interferon-gamma; Isoproterenol; Methacholine Chloride; Muscle, Smooth; Receptors, Adrenergic, beta; Trachea; Transforming Growth Factor beta | 2003 |
Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2.
Topics: Animals; Cell Division; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Isoproterenol; Lymphocytes; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; RNA, Messenger; Time Factors | 2003 |
Beta-adrenergic inhibition of rabbit lens anterior-surface K(+) conductance.
Topics: Adrenergic beta-Agonists; Animals; Biological Transport; Colforsin; Cyclic AMP; Electric Conductivity; Electrophysiology; Epinephrine; Epithelial Cells; Fluorescent Antibody Technique, Indirect; Isoproterenol; Lens, Crystalline; Potassium; Potassium Channels; Rabbits; Receptors, Adrenergic, beta-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Terbutaline | 2003 |
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction | 2003 |
Function of beta 2-adrenergic receptors in chronic localized myalgia.
Topics: Adrenergic beta-Agonists; Adult; Analysis of Variance; Case-Control Studies; Chronic Disease; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Facial Muscles; Facial Pain; Female; Fibromyalgia; Humans; Isoproterenol; Leukocytes, Mononuclear; Male; Neck Muscles; Receptors, Adrenergic, beta-2; Second Messenger Systems; Statistics, Nonparametric | 2003 |
Inotropic responses to isoproterenol in congestive heart failure subsequent to myocardial infarction in rats.
Topics: Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Colforsin; Coronary Vessels; Heart Failure; Isoproterenol; Ligation; Male; Myocardial Contraction; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1995 |
Regulation of the cAMP-elevating effects of isoproterenol and forskolin in cardiac myocytes by treatments that cause increases in cAMP.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoproterenol; Milrinone; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Response Elements; Rolipram | 2003 |
Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys.
Topics: Aging; Animals; Colforsin; Consciousness; Dihydropyridines; Female; Isoproterenol; Macaca fascicularis; Male; Norepinephrine; Ovary; Receptors, Adrenergic, beta; Sex Characteristics; Sympathetic Nervous System; Sympathomimetics | 2003 |
Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways.
Topics: Animals; Brain; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Embryo, Mammalian; Enzyme Activation; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Humans; Hypothalamic Hormones; Isoproterenol; Kidney; Melanins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Pituitary Hormones; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Receptors, Pituitary Hormone; Signal Transduction; src-Family Kinases; Transfection; Type C Phospholipases | 2003 |
Ischemic preconditioning prevents ischemia-induced beta-adrenergic receptor sequestration.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Cell Line; Cell Survival; Colforsin; Deoxyglucose; Humans; Ischemic Preconditioning; Ischemic Preconditioning, Myocardial; Isoproterenol; Kidney; Myocardial Ischemia; Potassium Cyanide; Radioligand Assay; Receptors, Adrenergic, beta | 2003 |
ATP release triggered by activation of the Ca2+-activated K+ channel in human airway Calu-3 cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Benzimidazoles; Bumetanide; Calcium; Cell Size; Charybdotoxin; Chlorzoxazone; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Epithelial Cells; Glyburide; Humans; Ionomycin; Isoproterenol; Luciferases; Lung; Potassium Channels, Calcium-Activated; Potassium Chloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1 | 2004 |
Lack of inverse agonistic activity of nebivolol, its D- and L-enantiomers and of in vivo metabolized nebivolol in human myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Benzopyrans; Colforsin; Ethanolamines; Humans; In Vitro Techniques; Isometric Contraction; Isoproterenol; Metoprolol; Myocardial Contraction; Myocardium; Nebivolol; Radioligand Assay; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship | 2003 |
Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzophenanthridines; Colforsin; Cyclosporine; Endothelin Receptor Antagonists; Endothelin-1; Female; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Phenylephrine; Protein Kinase C; Rabbits; Receptors, Adrenergic, beta; Receptors, Endothelin; Vasodilation | 2003 |
Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Amygdala; Animals; Benzazepines; Binding Sites; Brain Chemistry; Calmodulin; Caudate Nucleus; Cell Membrane; Colforsin; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fenoldopam; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Male; Microdissection; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulfur Isotopes; Tissue Distribution | 2003 |
Effects of ouabain on human bronchial muscle in vitro.
Topics: Acetylcholine; Bronchi; Calcium; Calcium Channel Blockers; Colforsin; Cromakalim; Histamine; Humans; In Vitro Techniques; Inositol Phosphates; Isoproterenol; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Ouabain; Protein Kinase C; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Regulation of myometrial phospholipase C system and uterine contraction by beta-adrenergic receptors in midpregnant rat.
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Animals; Cell Membrane; Colforsin; Female; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Myometrium; Phospholipase C beta; Potassium Channel Blockers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tetraethylammonium; Type C Phospholipases; Uterine Contraction | 2004 |
Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia.
Topics: Animals; Cardiotonic Agents; Colforsin; Delayed Rectifier Potassium Channels; Guinea Pigs; Histamine; Hypoxia; Isoproterenol; Myocardium; Oxidation-Reduction; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Protein Kinase C beta; Sulfhydryl Compounds; Time Factors | 2004 |
Pertussis toxin-sensitive G protein but not NO/cGMP pathway mediates the negative inotropic effect of carbachol in adult rat cardiomyocytes.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; GTP-Binding Proteins; Injections, Intraperitoneal; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Time Factors | 2004 |
Desensitisation of mast cell beta2-adrenoceptor-mediated responses by salmeterol and formoterol.
Topics: Albuterol; Cell Membrane; Colforsin; Cyclic AMP; Desensitization, Immunologic; Dose-Response Relationship, Drug; Ethanolamines; Female; Formoterol Fumarate; Histamine Release; Humans; Immunoglobulin E; Isoproterenol; Lung; Male; Mast Cells; Radioligand Assay; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Time Factors | 2004 |
Interleukin-1beta, transforming growth factor-beta1, and bradykinin attenuate cyclic AMP production by human pulmonary artery smooth muscle cells in response to prostacyclin analogues and prostaglandin E2 by cyclooxygenase-2 induction and downregulation o
Topics: Adenylyl Cyclases; Adult; Arachidonic Acid; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Epoprostenol; Gene Expression Regulation, Enzymologic; Growth Substances; Humans; Interleukin-1; Isoenzymes; Isoproterenol; Membrane Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Artery; RNA, Messenger; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Protein associated with Myc (PAM) is involved in spinal nociceptive processing.
Topics: Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Animals, Newborn; Antibodies; Carrier Proteins; Colforsin; Dose-Response Relationship, Drug; Embryo, Mammalian; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; GTP-Binding Protein alpha Subunits, Gs; Humans; In Situ Hybridization; In Vitro Techniques; Inflammation; Isoproterenol; Laminectomy; Male; Mixed Function Oxygenases; Neurons; Oligonucleotides, Antisense; Pain; Pain Measurement; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spinal Cord; Time Factors; Ubiquitin-Protein Ligases; Zymosan | 2004 |
Changes in the vascular beta-adrenoceptor-activated signalling pathway in 2Kidney-1Clip hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Caffeine; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Gene Expression; Glyburide; Hypertension, Renovascular; Isoproterenol; Kidney; Male; Membrane Proteins; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channels; Rats; Rats, Wistar; Receptors, Adrenergic, beta; RNA, Messenger; Sarcolemma; Signal Transduction; Thapsigargin; Vasoconstriction; Vasodilation | 2004 |
Post-translational modifications of tubulin and microtubule stability in adult rat ventricular myocytes and immortalized HL-1 cardiomyocytes.
Topics: Adrenergic beta-Agonists; Animals; Antineoplastic Agents; Caffeine; Calcium Signaling; Cell Line, Transformed; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Heart Ventricles; Isoproterenol; Male; Microtubules; Myocytes, Cardiac; Nocodazole; Phosphodiesterase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Wistar; Thapsigargin; Tubulin | 2004 |
Characterization of mexiletine as an antagonist of beta-adrenoceptor in Chinese hamster ovary cells expressing cloned human beta-adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Lidocaine; Mexiletine; Pindolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Transfection | 2004 |
Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Androstadienes; Animals; Bucladesine; Choline; Colforsin; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Isoproterenol; Phosphoinositide-3 Kinase Inhibitors; Phospholipids; Pyrimidines; Quinazolines; Rats; Receptors, Adrenergic, beta; Saliva; src-Family Kinases; Sublingual Gland; Transcriptional Activation; Wortmannin | 2004 |
Reduced uteroplacental blood flow alters renal arterial reactivity and glomerular properties in the rat offspring.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Adrenergic Agents; Adrenergic Fibers; Albuminuria; Animals; Birth Weight; Colforsin; Creatinine; Female; Fetal Distress; Hematocrit; Hypertension, Renal; Isoproterenol; Kidney Glomerulus; Ligation; Litter Size; Male; Nephrectomy; Phenylephrine; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Renal Artery; Serotonin; Uterus; Vasoconstriction | 2004 |
Antagonistic growth regulation of cell lines derived from human lung adenocarcinomas of Clara cell and aveolar type II cell lineage: Implications for chemoprevention.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Bronchi; Cell Division; Cell Lineage; Chemoprevention; Colforsin; Cyclic AMP; DNA; ErbB Receptors; Humans; Isoproterenol; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenotype; Pulmonary Alveoli; Transcriptional Activation; Tumor Cells, Cultured | 2004 |
Redox modulation of basal and beta-adrenergically stimulated cardiac L-type Ca(2+) channel activity by phenylarsine oxide.
Topics: Animals; Arsenicals; Calcium; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Dithiothreitol; Drug Evaluation, Preclinical; Electrophysiology; Guinea Pigs; Isoproterenol; Myocytes, Cardiac; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Signal Transduction; Thionucleotides; Time Factors | 2004 |
[Dissociation action of cationic peptides with hydrophobic radicals on functional coupling between serpentine type receptors and GTP-binding proteins].
Topics: Adenylyl Cyclases; Animals; Cations; Cell Membrane; Colforsin; Dose-Response Relationship, Drug; GTP-Binding Proteins; Isoproterenol; Mollusca; Muscle, Skeletal; Muscle, Smooth; Peptides; Rats; Signal Transduction | 2004 |
Regulation of Na(+)-K(+)-2Cl- cotransporter activity in rat skeletal muscle and intestinal epithelial cells.
Topics: Animals; Bumetanide; Butadienes; Cell Line; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastrointestinal Tract; Indoles; Isoproterenol; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Skeletal; Nitriles; Potassium; Rats; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sulfonamides | 2003 |
Adenylyl cyclase type VI gene transfer reduces phospholamban expression in cardiac myocytes via activating transcription factor 3.
Topics: Activating Transcription Factor 3; Adenylyl Cyclases; Animals; Binding Sites; Blotting, Northern; Blotting, Western; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cell Nucleus; Cells, Cultured; Cloning, Molecular; Colforsin; Cyclic AMP; Down-Regulation; Gene Transfer Techniques; Isoproterenol; Luciferases; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Plasmids; Promoter Regions, Genetic; Rats; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Transcription Factors; Transcription, Genetic; Transfection | 2004 |
Alterations of beta-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; beta-Adrenergic Receptor Kinases; Body Temperature; Catecholamines; Colforsin; Coronary Circulation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Female; Hematocrit; Hemodynamics; Hemoglobins; Isoproterenol; Leukocyte Count; Male; Myocardial Reperfusion Injury; Myocardium; Pericardium; Receptors, Adrenergic, beta; Time Factors | 2004 |
Secretion of gastric mucus phospholipids in response to beta-adrenergic G protein-coupled receptor activation is mediated by SRC kinase-dependent epidermal growth factor receptor transactivation.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cells, Cultured; Colforsin; ErbB Receptors; Flavonoids; Gastric Mucosa; Isoproterenol; Phospholipids; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; src-Family Kinases; Transcriptional Activation | 2004 |
cAMP inhibits transepithelial chloride secretion across bovine ciliary body/epithelium.
Topics: Animals; Aqueous Humor; Biological Transport, Active; Cattle; Chloride Channels; Chlorides; Ciliary Body; Colforsin; Cyclic AMP; Diffusion Chambers, Culture; Isoproterenol; Pigment Epithelium of Eye; Vasoactive Intestinal Peptide | 2004 |
Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenoviridae; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide-Gated Cation Channels; Diterpenes; Feedback; Ion Channels; Isoproterenol; Kinetics; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Recombinant Proteins; Sarcolemma; Signal Transduction | 2004 |
Protein kinase C and epidermal growth factor stimulation of Raf1 potentiates adenylyl cyclase type 6 activation in intact cells.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Line; CHO Cells; Colforsin; Cricetinae; DNA Primers; Enzyme Activation; Epidermal Growth Factor; Humans; Isoproterenol; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Kinase C; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
Topics: Androstadienes; Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Insulin-Like Growth Factor I; Ion Transport; Isoproterenol; Morpholines; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Patch-Clamp Techniques; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prazosin; Propanolamines; Protein Processing, Post-Translational; Rats; Receptors, Adrenergic, beta-1; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Wortmannin | 2004 |
Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2+.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Cations; Cattle; Colforsin; Copper; Dose-Response Relationship, Drug; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Diphosphate; Hydrogen Peroxide; Isoproterenol; Models, Molecular; Nucleotides; Protein Binding; Protein Structure, Tertiary; Rats; Signal Transduction; Time Factors; Zinc | 2005 |
Response to intra- and extracellular lipolytic agents and hormone-sensitive lipase translocation are impaired in adipocytes from rats adapted to a high-protein, carbohydrate-free diet.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; Bucladesine; Colforsin; Dietary Carbohydrates; Dietary Proteins; Glycerol; Isoproterenol; Lipolysis; Male; Rats; Rats, Wistar; Sterol Esterase | 2004 |
The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Colforsin; Dinoprost; Diphenylacetic Acids; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxotremorine; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2005 |
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic beta-Agonists; Amino Acids; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Dendritic Spines; Disks Large Homolog 4 Protein; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Immunoprecipitation; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Membrane Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Kinase Inhibitors; Pseudopodia; Pyrroles; Rats; Receptor, trkB; Thionucleotides; Transfection | 2005 |
Activation of alpha2-adrenoceptors is necessary to induce nitric oxide release in isoprenaline-induced relaxation.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Colforsin; Drug Interactions; Endothelium, Vascular; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasodilation | 2005 |
Beta-adrenergic hyperresponsiveness in compensated hypothyroidism associated with Down syndrome.
Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Child; Child, Preschool; Cholera Toxin; Colforsin; Cyclic AMP; Down Syndrome; Female; Gonadal Disorders; GTP-Binding Proteins; Humans; Hypothyroidism; Infant; Isoproterenol; Leukocytes, Mononuclear; Male; Receptors, Adrenergic, beta; Thyroid Hormones; Time Factors | 2005 |
Effects of the C-terminal peptide of the alphaS subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Biogenic Monoamines; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Glucagon; GTP-Binding Protein alpha Subunits; Guanylyl Imidodiphosphate; Isoproterenol; Mollusca; Muscles; Peptides; Rats; Sodium Fluoride | 2005 |
Insulin-induced changes in beta-adrenergic response: an experimental study in the isolated rat papillary muscle.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isoproterenol; Male; Muscle Contraction; Papillary Muscles; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2005 |
Functional changes in adenylyl cyclases and associated decreases in relaxation responses in mesenteric arteries from diabetic rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Glucose; Body Weight; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Immunoenzyme Techniques; Insulin; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Adenylate cyclase-mediated forms of neuronal plasticity in hippocampal area CA1 are reduced with aging.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Analysis of Variance; Animals; Colforsin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Activation; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Neuronal Plasticity; Neurons; Rats; Rats, Inbred F344; Time Factors | 2005 |
Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoproterenol; Maleimides; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Trachea | 2005 |
Angiotensin II-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells.
Topics: Adenylyl Cyclases; Angiotensin II; Cardiotonic Agents; Cells, Cultured; Colforsin; Dactinomycin; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoproterenol; Muscle, Smooth, Vascular; Parasympatholytics; RGS Proteins; Signal Transduction | 2005 |
Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adrenergic beta-Agonists; Animals; Cell Culture Techniques; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Cytokines; Depression, Chemical; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucocorticoids; Growth Hormone; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Nicotinamide Phosphoribosyltransferase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Isoproterenol opens K+(ATP) channels via a beta2-adrenoceptor-linked mechanism in Sertoli cells from immature rats.
Topics: Adrenergic beta-Agonists; Animals; ATP-Binding Cassette Transporters; Colforsin; Dose-Response Relationship, Drug; Electrophysiology; Glyburide; Hypoglycemic Agents; Ion Channel Gating; Isoproterenol; KATP Channels; Lanthanum; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Sertoli Cells; Testosterone | 2005 |
Modulation of voltage-dependent Ba2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent pathways.
Topics: Animals; Barium; Bucladesine; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocytes, Smooth Muscle; Peptides; Pyloric Antrum; Thionucleotides | 2005 |
Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP2/EP4 receptors and SP-1 transcription factor binding sites.
Topics: Base Sequence; Binding Sites; Cell Survival; Cells, Cultured; Chromatin Immunoprecipitation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Gene Deletion; Humans; Isoproterenol; Luciferases; Molecular Sequence Data; Mutation; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Binding; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA; RNA, Messenger; Sp1 Transcription Factor; Time Factors; Trachea; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A | 2005 |
Effects of streptozotocin-induced diabetes on Kv channels in rat small coronary smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Colforsin; Coronary Vessels; Diabetes Mellitus, Experimental; Female; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Streptozocin; Vasodilation | 2005 |
High efficiency activation of L-type Ca2+ current by 5-HT in human atrial myocytes.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Calcium; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Atria; Humans; Isoproterenol; Male; Middle Aged; Muscle Cells; Myocardium; Serotonin; Time Factors | 2004 |
Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Carboxylic Ester Hydrolases; Cholera Toxin; Colforsin; Down-Regulation; Insulin; Isoproterenol; Lipase; Mice; Mitogen-Activated Protein Kinase 3; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; beta-Galactosidase; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Genetic Complementation Test; Humans; Isoproterenol; Mutation; Propanolamines; Propranolol; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Salmeterol Xinafoate; Transfection | 2005 |
Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Benzoates; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Glyburide; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred CFTR; Muscle, Smooth, Vascular; ortho-Aminobenzoates; Quinolizines; Serotonin; Thiazoles; Thiazolidines; Vasoactive Intestinal Peptide; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding.
Topics: Adrenergic beta-Agonists; Aging; Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Cortex; Colforsin; GABA Agonists; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Rats; Rats, Wistar; Receptors, Drug; Suramin | 2005 |
Effect of chronic exposure to cold on isoprenaline-induced cAMP accumulation and relaxation in the rat aorta.
Topics: Acclimatization; Animals; Aorta; Blood Pressure; Bucladesine; Cold Temperature; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasodilation | 2006 |
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands.
Topics: Adenylyl Cyclases; Animals; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Bradykinin; Calcium; Chelating Agents; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Gene Expression Regulation, Enzymologic; Immunoblotting; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Isoproterenol; Male; Melatonin; Norepinephrine; Pertussis Toxin; Phosphodiesterase Inhibitors; Pineal Gland; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Superior Cervical Ganglion; Time Factors; Transcriptional Activation; Type C Phospholipases | 2005 |
Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility.
Topics: Actin Cytoskeleton; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Calcium; Colforsin; Electric Stimulation; Endoplasmic Reticulum; Fibroblasts; In Vitro Techniques; Isoproterenol; Matrix Metalloproteinase 2; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Fluorescence; Myocardial Contraction; Myocardium; Sarcomeres; Stimulation, Chemical; Ventricular Dysfunction, Left; Ventricular Remodeling | 2006 |
Beta-adrenergic stimulation does not activate Na+/Ca2+ exchange current in guinea pig, mouse, and rat ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Guinea Pigs; Heart Ventricles; Isoproterenol; Mice; Myocytes, Cardiac; Nickel; Patch-Clamp Techniques; Rats; Receptors, Adrenergic, beta; Signal Transduction; Sodium; Sodium-Calcium Exchanger | 2006 |
Selective activation of adrenergic beta1 receptors induces heme oxygenase 1 production in RAW264.7 cells.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Catecholamines; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Heme Oxygenase-1; Isoproterenol; Macrophages; Mice; Oxidative Stress; Protoporphyrins; Receptors, Adrenergic, beta-1 | 2005 |
The impact of blunted beta-adrenergic responsiveness on growth regulatory pathways in hypertension.
Topics: Adrenergic beta-Agonists; Animals; Base Sequence; Cell Proliferation; Cells, Cultured; Colforsin; DNA Primers; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hypertension; Isoproterenol; Male; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2006 |
The beta-agonist isoproterenol attenuates EGF-stimulated wound closure in human airway epithelial cells.
Topics: Adrenergic beta-Agonists; Bacterial Proteins; Bronchi; Cells, Cultured; Colforsin; Cyclic AMP; Drug Combinations; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Humans; Isoproterenol; Luminescent Proteins; Mitogen-Activated Protein Kinases; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Signal Transduction; Wound Healing | 2006 |
Effects of forskolin on Kupffer cell production of interleukin-10 and tumor necrosis factor alpha differ from those of endogenous adenylyl cyclase activators: possible role for adenylyl cyclase 9.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Interleukin-10; Isoproterenol; Kupffer Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Signal Transduction; Thionucleotides; Tumor Necrosis Factor-alpha | 2005 |
Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Carbachol; Cell Membrane; Chlorpyrifos; Cholinergic Agonists; Cholinesterase Inhibitors; Colforsin; Drug Combinations; Drug Interactions; Female; Heart; Isoproterenol; Male; Myocardium; Pregnancy; Protein Binding; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Adrenergic, beta; Sex Factors; Signal Transduction; Terbutaline | 2005 |
Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20.
Topics: Adenylyl Cyclases; Animals; Carbachol; Carotid Arteries; Colforsin; Cyclic GMP; Enzyme Activation; HSP20 Heat-Shock Proteins; Immunologic Techniques; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myosin Light Chains; Phosphorylation; Rabbits; Staining and Labeling; Swine; Urinary Bladder | 2005 |
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Onium Compounds; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Superoxides | 2005 |
Scar myofibroblasts of the infarcted rat heart express natriuretic peptides.
Topics: Adrenomedullin; Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Cicatrix; Colforsin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptides; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serine Endopeptidases | 2006 |
Adenosine-stimulated atrial natriuretic peptide release through A1 receptor subtype.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2005 |
Modulation of monocarboxylic acid transporter-1 kinetic function by the cAMP signaling pathway in rat brain endothelial cells.
Topics: Animals; Brain; Brain Ischemia; Calibration; Colforsin; Coumaric Acids; Cyclic AMP; Cytoplasm; Endothelial Cells; Enzyme Inhibitors; Hydrogen-Ion Concentration; Immunohistochemistry; Isoproterenol; Isoquinolines; Kinetics; Microscopy, Fluorescence; Models, Biological; Monocarboxylic Acid Transporters; Radioimmunoassay; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Symporters | 2006 |
Presynaptic mechanism underlying cAMP-induced synaptic potentiation in medial prefrontal cortex pyramidal neurons.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Transport Vesicles | 2006 |
Ontogeny and effects of thyroid hormone on beta1-adrenergic receptor mRNA expression in ovine fetal kidney cortex.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Female; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Isoproterenol; Kidney Cortex; Pregnancy; Receptors, Adrenergic, beta-1; Renin; RNA, Messenger; Sheep; Thyroidectomy; Thyroxine | 2005 |
D2 dopamine receptor-induced sensitization of adenylyl cyclase type 1 is G alpha(s) independent.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; GTP-Binding Protein alpha Subunits; Hybrid Cells; Ionophores; Isoproterenol; Mice; Quinpirole; Rabbits; Receptors, Dopamine D2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tritium | 2006 |
Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling.
Topics: Adenylyl Cyclases; Amino Acids; Animals; Biotinylation; Brain; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; Glutathione Transferase; Hippocampus; Isoproterenol; Membrane Proteins; Mutation; Neuroglia; Neurons; Phosphoproteins; Rats; Receptors, Adrenergic, beta; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Signal Transduction | 2006 |
Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Bucladesine; Cell Line; Cholera Toxin; Chromones; Colforsin; Cyclic AMP; Dideoxyadenosine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanolamines; Glucose; Isoproterenol; Morpholines; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Rats; Receptors, Adrenergic, beta-2; Rolipram; Signal Transduction | 2006 |
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea | 2006 |
Levalbuterol inhibits human airway smooth muscle cell proliferation: therapeutic implications in the management of asthma.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Asthma; Bronchodilator Agents; Cell Line; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Isoproterenol; Morpholines; Muscle, Smooth; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipid Ethers; Platelet Aggregation Inhibitors; Propanolamines; Retinoblastoma Protein | 2006 |
Ca2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP.
Topics: Adenylyl Cyclases; Alprostadil; Biological Clocks; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Catalysis; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Isoproterenol; Time Factors | 2006 |
8-OH-DPAT attenuates isoproterenol- but not forskolin-stimulated accumulation of cAMP in mediobasal hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Colforsin; Cyclic AMP; Female; Hypothalamus; In Vitro Techniques; Isoproterenol; Rats; Rats, Inbred F344 | 2006 |
Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Apyrase; Calcium Signaling; Cells, Cultured; Cilia; Colforsin; Epithelial Cells; Hexokinase; In Vitro Techniques; Ionomycin; Isoproterenol; Lung; Mice; Mice, Inbred BALB C; Temperature; Trachea | 2006 |
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium | 2006 |
Regulation of human vascular smooth muscle cell migration by beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Cell Movement; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Intracellular Fluid; Isoproterenol; Muscle, Smooth, Vascular; Phenylephrine; Platelet-Derived Growth Factor; Radioimmunoassay; Receptors, Adrenergic, beta; Saphenous Vein; Spectrophotometry | 2006 |
Isoproterenol stimulates monocyte chemoattractant protein-1 expression and secretion in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Cell Differentiation; Cell Line; Chemokine CCL2; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Isoproterenol; Mice; RNA, Messenger | 2006 |
Regional differences in adipose tissue metabolism in women: minor effect of obesity and body fat distribution.
Topics: Adipocytes; Adipose Tissue; Adult; Aged; Blood Pressure; Body Fat Distribution; Body Size; Body Weight; Bucladesine; Colforsin; Female; Humans; Isoproterenol; Lipoprotein Lipase; Middle Aged; Omentum; Organ Size; Skin; Viscera | 2006 |
Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation.
Topics: Adrenergic beta-Agonists; Animals; Association Learning; Avoidance Learning; Colforsin; Conditioning, Psychological; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Isoproterenol; Male; MAP Kinase Signaling System; Maze Learning; Memory; Mice; Mice, Mutant Strains; Neuronal Plasticity; Neurons; Phorbol Esters; Protein Kinase C; Protein Kinases; Theta Rhythm | 2006 |
Tissue inhibitor of metalloproteinase 1 expression and secretion are induced by beta-adrenergic stimulation in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adrenergic beta-Agonists; Animals; Bucladesine; Cell Line, Transformed; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Insulin; Isoproterenol; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Up-Regulation | 2006 |
17beta-estradiol potentiates the cardiac cystic fibrosis transmembrane conductance regulator chloride current in guinea-pig ventricular myocytes.
Topics: Animals; Cardiotonic Agents; Catecholamines; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electrophysiology; Estradiol; Estrogen Antagonists; Evoked Potentials; Fulvestrant; Guinea Pigs; Isoproterenol; Membrane Potentials; Myocytes, Cardiac; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Protein Binding; Receptors, Adrenergic, beta; Receptors, Estrogen | 2006 |
Cold exposure stimulates synthesis of the bioactive lipid oleoylethanolamide in rat adipose tissue.
Topics: Acyltransferases; Adipocytes; Adipose Tissue; Animals; Cold Temperature; Colforsin; Endocannabinoids; Epididymis; Isoproterenol; Lipid Metabolism; Male; Norepinephrine; Oleic Acids; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2006 |
Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Delayed Rectifier Potassium Channels; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium; Rats; Rats, Wistar; Signal Transduction; Sympathetic Nervous System; Sympathomimetics | 2006 |
Cyclic AMP formation in C6 glioma cells: effect of PACAP and VIP in early and late passages.
Topics: Animals; Cell Line, Tumor; Cellular Senescence; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Time Factors; Vasoactive Intestinal Peptide | 2006 |
Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Atrial Natriuretic Factor; Captopril; Colforsin; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Artery Obstruction; Signal Transduction; Sodium Fluoride; Time Factors | 2006 |
The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Kidney; Mice; Mice, Inbred C57BL; Renin; RNA, Small Interfering; Thapsigargin | 2006 |
Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles.
Topics: Adrenergic beta-Agonists; Aging; Animals; Arterioles; Colforsin; Enzyme Inhibitors; Hindlimb; Isoproterenol; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2007 |
Effects of forskolin on inotropic performance and phospholamban phosphorylation in exercise-trained hypertensive myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium-Binding Proteins; Colforsin; Cyclic AMP; Female; Heart Rate; Hypertension; Isoproterenol; Myocardial Contraction; Myocardium; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Ventricular Function, Left | 2007 |
Ca2+-independent, inhibitory effects of cyclic adenosine 5'-monophosphate on Ca2+ regulation of phosphoinositide 3-kinase C2alpha, Rho, and myosin phosphatase in vascular smooth muscle.
Topics: Animals; Bucladesine; Calcium; Class II Phosphatidylinositol 3-Kinases; Colforsin; Cyclic AMP; Isoproterenol; Male; Membrane Potentials; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rabbits; Vasoconstriction | 2007 |
Mechanisms of relaxant action of a crude hexane extract of Gnaphalium liebmannii in guinea pig tracheal smooth muscle.
Topics: Aminophylline; Animals; Bronchodilator Agents; Colforsin; Dose-Response Relationship, Drug; Gnaphalium; Guinea Pigs; Hexanes; In Vitro Techniques; Isoproterenol; Male; Methanol; Methylene Chloride; Mexico; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Plant Extracts; Solvents; Trachea | 2007 |
Functional analysis of endogenous beta-adrenergic receptor through fluorimetric monitoring of cyclic nucleotide-gated ion channel.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cell Line; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Fluorometry; Humans; Ion Channels; Isoproterenol; Metoprolol; Receptors, Adrenergic, beta | 2007 |
Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.
Topics: Animals; Arginine; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2007 |
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diastole; Heart Failure; Isoproterenol; Isoquinolines; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Peptides; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Sulfonamides; Tetracaine | 2007 |
Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; Extracellular Fluid; Humans; In Vitro Techniques; Intracellular Fluid; Isoproterenol; Mammary Arteries; Milrinone; Phenylephrine; Potassium Chloride; Radial Artery; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea | 2007 |
Inhibitory effect of NPY on isoprenaline-induced osteoclastogenesis in mouse bone marrow cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bone Marrow Cells; Bone Resorption; Bucladesine; Calcitriol; Cells, Cultured; Colforsin; Enzyme Activation; Isoproterenol; Male; Mice; Mice, Mutant Strains; Neuropeptide Y; Osteoclasts; RANK Ligand; Receptors, Adrenergic, beta-2; Receptors, Neuropeptide Y; Vitamins | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Alzheimer amyloid beta-peptide A-beta25-35 blocks adenylate cyclase-mediated forms of hippocampal long-term potentiation.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Colforsin; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Long-Term Potentiation; Magnesium; Male; Peptide Fragments; Rats; Rats, Inbred F344; Synapses; Synaptic Transmission | 2007 |
[Effects of nitrous oxide and isoflurane on the L-type calcium current of rabbit ventricular myocytes and their modulation by beta-adrenoceptor stimulation].
Topics: Anesthetics; Animals; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Drug Combinations; Heart Ventricles; Isoflurane; Isoproterenol; Myocytes, Cardiac; Nitrous Oxide; Patch-Clamp Techniques; Rabbits; Receptors, Adrenergic, beta | 2007 |
A CE assay for the detection of agonist-stimulated adenylyl cyclase activity.
Topics: Adenylyl Cyclases; Biological Assay; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Capillary; Enzyme Activators; Isoproterenol; Receptors, G-Protein-Coupled; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substrate Specificity; Terbutaline | 2007 |
Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Colforsin; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Isoproterenol; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Signal Transduction | 2007 |
beta-adrenoceptor agonists downregulate adiponectin, but upregulate adiponectin receptor 2 and tumor necrosis factor-alpha expression in adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adiponectin; Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethanolamines; Fenoterol; Gene Expression Regulation; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Protein Serine-Threonine Kinases; Receptors, Adiponectin; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation | 2007 |
PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Blood Vessels; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Humans; In Vitro Techniques; Isoproterenol; Molecular Sequence Data; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Drug; Sulfonylurea Receptors | 2007 |
Decrease in functional activity of G-proteins hormone-sensitive adenylate cyclase signaling system, during experimental type II diabetes mellitus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bromocriptine; Cardiotonic Agents; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Hormone Antagonists; Hormones; Isoproterenol; Myocardium; Peptides; Rats; Rats, Wistar; Relaxin; Serotonin; Serotonin Agents; Signal Transduction; Somatostatin | 2006 |
Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Mice; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Troponin I | 2007 |
Cholesterol depletion modulates basal L-type Ca2+ current and abolishes its -adrenergic enhancement in ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; beta-Cyclodextrins; Calcium Channel Agonists; Calcium Channels, L-Type; Calcium Signaling; Cholesterol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Dose-Response Relationship, Drug; Enzyme Activators; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Microdomains; Membrane Potentials; Myocytes, Cardiac; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors | 2008 |
The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.
Topics: Animals; Cattle; Colforsin; Cyclic AMP-Dependent Protein Kinases; HSP20 Heat-Shock Proteins; Isoproterenol; Kinetics; Muscle Relaxation; Muscle, Smooth; Phosphopeptides; Respiratory Physiological Phenomena; Serotonin | 2008 |
NMDA receptor activation dephosphorylates AMPA receptor glutamate receptor 1 subunits at threonine 840.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Enzyme Inhibitors; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Hippocampus; Humans; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mutagenesis; Neurons; Protein Array Analysis; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Threonine; Transfection | 2007 |
Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery.
Topics: Adrenergic beta-Agonists; Animals; Cadherins; Capillary Permeability; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indicators and Reagents; Isoproterenol; Male; Microscopy, Confocal; Phosphodiesterase Inhibitors; Platelet Activating Factor; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Rolipram; Signal Transduction; Splanchnic Circulation | 2008 |
Changed sensitivity of adenylate cyclase signaling system to biogenic amines and peptide hormones in tissues of starving rats.
Topics: Adenylyl Cyclases; Animals; Biogenic Amines; Brain; Bromocriptine; Colforsin; Guanosine Triphosphate; Heart; Isoproterenol; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Serotonin; Signal Transduction; Somatostatin; Starvation | 2007 |
Negative regulation of beta-adrenergic function by hydrogen sulphide in the rat hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Calcium Signaling; Colforsin; Cyclic AMP; Electric Stimulation; Hydrogen Sulfide; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 2008 |
EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase.
Topics: Adenylyl Cyclases; Apoptosis; B-Lymphocytes; Camptothecin; Cell Line; Cell Proliferation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Herpesvirus 4, Human; Humans; Isoproterenol; Signal Transduction | 2008 |
Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Activators; Hypertension; Isoproterenol; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides | 2008 |
Circulating IL-6 concentrations and abdominal adipocyte isoproterenol-stimulated lipolysis in women.
Topics: Absorptiometry, Photon; Adipocytes; Adiposity; Adrenergic beta-Agonists; Adult; Cell Size; Colforsin; Cross-Sectional Studies; Cyclic CMP; Dose-Response Relationship, Drug; Female; Glycerol; Humans; Interleukin-6; Intra-Abdominal Fat; Isoproterenol; Lipolysis; Lipoprotein Lipase; Middle Aged; Radioimmunoassay; Subcutaneous Fat, Abdominal; Tomography, X-Ray Computed | 2008 |
Modulation of {beta}-adrenoceptor signaling in the hearts of 4-wk simulated weightlessness rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Body Weight; Colforsin; Cyclic AMP; Electric Stimulation; Heart; Hindlimb Suspension; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction; Myocytes, Cardiac; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Weightlessness Simulation | 2008 |
Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects.
Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adult; Animals; Brain; Colforsin; Female; Humans; Isoproterenol; Male; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Smoking | 2008 |
Chloride conductance in amphibian skin: regulatory control in the skin of Rana pipiens.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chlorides; Colforsin; Cyclic AMP; Electric Conductivity; Epinephrine; Galvanic Skin Response; In Vitro Techniques; Isoproterenol; Rana pipiens; Skin Physiological Phenomena | 2008 |
Role of putrescine on androgen-elicited positive inotropism in the left atrium of rats.
Topics: Adrenergic beta-Agonists; Androgens; Animals; Atrial Function; Cardiotonic Agents; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dihydrotestosterone; Eflornithine; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2008 |
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines | 2008 |
Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Nerve Tissue Proteins; Peptides; Receptors, Adrenergic, beta; Synaptotagmins; Urinary Bladder; Urinary Incontinence | 2008 |
Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Cell Line; Colforsin; Cyclic AMP; Enzyme Activators; Humans; Ion Channel Gating; Isoproterenol; KCNQ1 Potassium Channel; Kinetics; Membrane Potentials; Models, Cardiovascular; Potassium; Potassium Channels, Voltage-Gated; Receptors, Adrenergic, beta; Recombinant Proteins; Temperature; Thionucleotides; Transfection | 2008 |
Preservation of the positive lusitropic effect of beta-adrenoceptors stimulation in diabetic cardiomyopathy.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Colforsin; Diabetes Complications; Diabetes Mellitus, Experimental; Echocardiography; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Phentolamine; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2008 |
cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Enzyme Activators; Fetus; Gene Expression Regulation; Isoproterenol; Isoquinolines; Mice; Myocytes, Cardiac; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Phenylephrine; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; RNA, Messenger; Signal Transduction; Sulfonamides | 2008 |
Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Calcium Signaling; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Protein alpha Subunits, Gs; Guanine Nucleotide Exchange Factors; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intercellular Junctions; Isoproterenol; Parathyroid Hormone; Phosphoric Diester Hydrolases; Protein Binding; Protein Isoforms | 2008 |
Laminin acts via focal adhesion kinase/phosphatidylinositol-3' kinase/protein kinase B to down-regulate beta1-adrenergic receptor signalling in cat atrial myocytes.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channels, L-Type; Cats; Chromones; Colforsin; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Humans; Isoproterenol; Laminin; Male; Morpholines; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propanolamines; Proto-Oncogene Proteins c-akt; Receptors, Adrenergic, beta; Signal Transduction | 2009 |
Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock.
Topics: Adrenergic beta-2 Receptor Agonists; Case-Control Studies; Colforsin; Flow Cytometry; GTP-Binding Proteins; Humans; Isoproterenol; Leukocytes, Mononuclear; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rolipram; Shock, Septic; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2008 |
Monoamines block kainate- and carbachol-induced gamma-oscillations but augment stimulus-induced gamma-oscillations in rat hippocampus in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biogenic Monoamines; Carbachol; Central Nervous System Agents; Colforsin; Dopamine; Electric Stimulation; Fenfluramine; Hippocampus; In Vitro Techniques; Isoproterenol; Kainic Acid; Membrane Potentials; Norepinephrine; Pyramidal Cells; Rats; Rats, Wistar; Serotonin; Serotonin Agents | 2009 |
Nuclear targeting of FBPase in HL-1 cells is controlled by beta-1 adrenergic receptor-activated Gs protein signaling cascade.
Topics: Active Transport, Cell Nucleus; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Line; Cell Nucleus; Colforsin; Culture Media; Cyclic AMP-Dependent Protein Kinases; Fructose-Bisphosphatase; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Metoprolol; Mice; Myocytes, Cardiac; Norepinephrine; Receptors, Adrenergic, beta-1; Second Messenger Systems | 2009 |
Direct spatial control of Epac1 by cyclic AMP.
Topics: Adrenergic beta-Agonists; Cell Adhesion; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Humans; Isoproterenol; rap GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction | 2009 |
Characterization of mouse heart adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catalysis; Cations, Divalent; Cell Line; Cell Membrane; Colforsin; Enzyme Inhibitors; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoenzymes; Isoproterenol; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Myocardium; Protein Isoforms; Receptors, G-Protein-Coupled; Recombinant Proteins; Spodoptera | 2009 |
Phosphorylation of myristoylated alanine-rich C kinase substrate is involved in the cAMP-dependent amylase release in parotid acinar cells.
Topics: Acetophenones; Amylases; Animals; Benzopyrans; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Male; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; Parotid Gland; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Rats, Sprague-Dawley; Sulfonamides | 2009 |
Thiamylal and thiopental attenuate beta-adrenergic signaling pathway by suppressing adenylyl cyclase in rat ventricular myocytes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Heart Ventricles; Humans; Hypnotics and Sedatives; Isoproterenol; Male; Myocytes, Cardiac; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Thiamylal; Thiopental | 2009 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Drug; Humans; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Potassium Chloride; Rats; Rats, Wistar; Serotonin; Urinary Bladder; Urinary Bladder, Overactive | 2009 |
Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Enzyme Activation; Isoproterenol; Mutation; Myocytes, Cardiac; Phosphoprotein Phosphatases; Protein Conformation; Proto-Oncogene Proteins c-akt; Rats; Transfection | 2009 |
Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Colforsin; Cyclic AMP; Disease Models, Animal; Hypertension, Renovascular; Isoproterenol; Kidney; Male; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Renal Circulation; Sensitivity and Specificity; Xanthines | 2009 |
Phosphodiesterase inhibition by naloxone augments the inotropic actions of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Naloxone; Narcotic Antagonists; Papillary Muscles; Phosphodiesterase 3 Inhibitors; Phosphodiesterase Inhibitors | 2009 |
Calcium-sensing receptors modulate renin release in vivo and in vitro in the rat.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Aniline Compounds; Animals; Calcium Chloride; Captopril; Cells, Cultured; Colforsin; In Vitro Techniques; Isoproterenol; Juxtaglomerular Apparatus; Male; Phenethylamines; Propylamines; Rats; Rats, Wistar; Receptors, Calcium-Sensing; Renin; Renin-Angiotensin System | 2009 |
The role of membrane microdomains in shaping beta2-adrenergic receptor-mediated cAMP dynamics.
Topics: Adrenergic Agonists; beta-Cyclodextrins; Biosensing Techniques; Blotting, Western; Cell Line; Cholesterol; Colforsin; Cyclic AMP; Humans; Isoproterenol; Membrane Microdomains; Receptors, Adrenergic, beta; Receptors, Prostaglandin E | 2009 |
CFTR Cl- channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish.
Topics: Animals; Clonidine; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Focal Adhesion Protein-Tyrosine Kinases; Fundulidae; Hypertonic Solutions; Hypotonic Solutions; Ion Transport; Isoproterenol; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Mitochondria; Phosphorylation; Protein Transport; Sympatholytics; Sympathomimetics; Tyrosine | 2009 |
A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.
Topics: Calcium; Cell Differentiation; Cell Line; Colforsin; Desensitization, Immunologic; Dimethyl Sulfoxide; Humans; Inflammation Mediators; Isoproterenol; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Peptides, Cyclic; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Second Messenger Systems | 2010 |
Chronic treatment with escitalopram but not R-citalopram translocates Galpha(s) from lipid raft domains and potentiates adenylyl cyclase: a 5-hydroxytryptamine transporter-independent action of this antidepressant compound.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Cell Line, Tumor; Citalopram; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Membrane Microdomains; Protein Transport; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship | 2010 |
beta2-Adrenoceptor, Gs and adenylate cyclase coupling in purified detergent-resistant, low density membrane fractions.
Topics: Adenylyl Cyclases; Caveolae; Cell Fractionation; Cell Line; Cell Membrane; Colforsin; Detergents; Glucosides; GTP-Binding Protein alpha Subunits, Gs; Humans; Isoproterenol; Kidney; Membrane Microdomains; Receptors, Adrenergic, beta-2; Signal Transduction | 2010 |
ADP-ribosylation factor 6 modulates adrenergic stimulated lipolysis in adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adrenergic beta-Agonists; Animals; Colforsin; Endocytosis; Insulin; Isoproterenol; Lipolysis; Mice; Mice, Obese; Phosphodiesterase Inhibitors; RNA Interference; RNA, Small Interfering; Signal Transduction; Triglycerides | 2010 |
Atrial natriuretic peptide regulates Ca channel in early developmental cardiomyocytes.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atrial Natriuretic Factor; Base Sequence; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Colforsin; DNA Primers; Embryonic Stem Cells; Enzyme Inhibitors; Fluorescent Antibody Technique; Heart; Isoproterenol; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Carcinogens; Cell Line, Transformed; Cell Line, Tumor; Cholinergic Agonists; Colforsin; Cyclic AMP; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Isoproterenol; Male; Oxygen Consumption; Parotid Gland; Phosphorylation; Protein Kinase C; raf Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Second Messenger Systems; Submandibular Gland; Tetradecanoylphorbol Acetate | 2010 |
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Animals; Bleomycin; Calcium-Binding Proteins; Catecholamines; Colforsin; Collagen; Cyclic AMP; Epoprostenol; Fibroblasts; Isoproterenol; Lung; Membrane Microdomains; Mice; Mice, Transgenic; Pulmonary Fibrosis; Rats; S100 Calcium-Binding Protein A4; S100 Proteins; Signal Transduction | 2010 |
Functional study of mucus secretion of the eustachian tube in Guinea pigs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Colforsin; Computer Systems; Cyclic AMP; Eustachian Tube; Exocrine Glands; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mucus; Nicotinic Agonists; Phenylephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Substance P | 2010 |
Type 4 phosphodiesterase plays different integrating roles in different cellular domains in pyramidal cortical neurons.
Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Cell Membrane; Central Nervous System Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dendrites; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Parietal Lobe; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Potassium; Pyramidal Cells; Receptors, Adrenergic, beta-1; Rolipram | 2010 |
Mucus secretion from individual submucosal glands of the ferret trachea.
Topics: Animals; Anions; Bronchodilator Agents; Carbachol; Cholinergic Agonists; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Exocrine Glands; Ferrets; Humans; Isoproterenol; Mucus; Muscle, Smooth; Phenylephrine; Sheep; Swine; Trachea; Vasoactive Intestinal Peptide; Vasoconstrictor Agents | 2010 |
Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Apoptosis; Colforsin; Echocardiography; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Isoproterenol; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Stress, Physiological; Ventricular Dysfunction, Left | 2010 |
Acute stimulation of white adipocyte respiration by PKA-induced lipolysis.
Topics: Adipocytes, White; Aerobiosis; Anaerobiosis; Animals; Bucladesine; Colforsin; Cyclic AMP; Humans; Ion Channels; Isoproterenol; Isoquinolines; Male; Mice; Mice, Knockout; Mitochondrial Proteins; Oxygen Consumption; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sulfonamides; Uncoupling Protein 2 | 2010 |
Hyposmotic challenge modulates function of L-type calcium channel in rat ventricular myocytes through protein kinase C.
Topics: Animals; Calcium Channels, L-Type; Cell Culture Techniques; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Female; Heart Ventricles; Ion Channel Gating; Isoproterenol; Membrane Potentials; Myocytes, Cardiac; Osmolar Concentration; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction | 2010 |
Thiol-oxidation reduces the release of amylase induced by β-adrenergic receptor activation in rat parotid acinar cells.
Topics: Amylases; Animals; Colforsin; Cyclic AMP; Diamide; Dithiothreitol; Glutathione; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isoproterenol; Male; Oxidation-Reduction; Parotid Gland; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Wasp Venoms | 2010 |
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
Topics: Adenine; Adenosine Triphosphate; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotide Exchange Factors; Humans; Iloprost; In Vitro Techniques; Isoproterenol; Models, Biological; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides | 2011 |
Receptor specific crosstalk and modulation of signaling upon heterodimerization between β1-adrenergic receptor and somatostatin receptor-5.
Topics: Calcineurin; Cell Communication; Cell Line; Colforsin; Cyclic AMP; Dimerization; Humans; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NFATC Transcription Factors; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor Cross-Talk; Receptors, Adrenergic, beta-1; Receptors, Somatostatin; Signal Transduction; Somatostatin | 2011 |
Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Cells, Cultured; Colforsin; Computational Biology; Cyclic AMP-Dependent Protein Kinases; Heart; HEK293 Cells; Humans; Isoproterenol; Mice; Molecular Sequence Data; Myocardium; Phosphorylation; Rats; Sequence Homology, Amino Acid; Sodium-Calcium Exchanger | 2011 |
Perinatal hypoxia enhances cyclic adenosine monophosphate-mediated BKCa channel activation in adult murine pulmonary artery.
Topics: Age Factors; Animals; Colforsin; Cyclic AMP; Female; Hypoxia; Isoproterenol; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Artery | 2011 |
Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Aged; Colforsin; Female; Humans; Hypoglycemic Agents; Inflammation; Interleukin-1beta; Isoproterenol; Lipolysis; Lipopolysaccharides; Male; Metformin; Middle Aged; Phosphorylation; Primary Cell Culture; Serine; Sterol Esterase; Tumor Necrosis Factor-alpha | 2011 |
Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase γ and phosphodiesterase 3B.
Topics: Acylation; Adipocytes; Adrenergic beta-Agonists; Animals; Benzimidazoles; Blotting, Western; Cells, Cultured; Class Ib Phosphatidylinositol 3-Kinase; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Drug Interactions; Ghrelin; Glycerol; Intra-Abdominal Fat; Isoproterenol; Lipolysis; Male; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolones; Quinoxalines; Rats; Rats, Wistar; Thiazolidinediones | 2011 |
β-Adrenoceptor/PKA-stimulation, Na(+)-Ca(2+) exchange and PKA-activated Cl(-) currents in rabbit cardiomyocytes: a conundrum.
Topics: Animals; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electrophysiological Phenomena; Isoproterenol; Myocytes, Cardiac; Nickel; Patch-Clamp Techniques; Rabbits; Receptors, Adrenergic, beta; Sodium-Calcium Exchanger | 2011 |
Effect of dibutyryl cyclic adenosine monophosphate on the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Bucladesine; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Hypertrophy; Isoproterenol; Lipid Metabolism; Mice; Phosphodiesterase Inhibitors; Plasminogen Activator Inhibitor 1; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thromboplastin | 2011 |
Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells.
Topics: Amino Acid Substitution; Animals; Antibodies; Antibody Specificity; Aquaporin 5; Calcimycin; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Detergents; Humans; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred ICR; Parotid Gland; Phosphorylation; Pilocarpine; Protein Kinase Inhibitors; Protein Transport; Salivary Glands; Signal Transduction; Submandibular Gland; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2011 |
Modified cAMP derivatives: powerful tools in heart research.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Dogs; Guanine Nucleotide Exchange Factors; Isoproterenol; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Signal Transduction | 2011 |
Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction.
Topics: Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Down-Regulation; G-Protein-Coupled Receptor Kinase 2; GTP-Binding Protein alpha Subunits, Gs; Guinea Pigs; Isoproterenol; KCNQ1 Potassium Channel; Male; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Refractory Period, Electrophysiological; Signal Transduction; Systole; Ventricular Remodeling | 2011 |
G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Disease Models, Animal; Dopamine Agonists; Down Syndrome; Environment; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Isoproterenol; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Norepinephrine; Signal Transduction | 2011 |
Homeostasis of extracellular ATP in human erythrocytes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carbenoxolone; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Homeostasis; Humans; Hydrolysis; Isoproterenol; Kinetics; Luciferases; Microscopy, Fluorescence; Papaverine; Peptides; Xenopus | 2011 |
Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells.
Topics: Adrenergic beta-Agonists; Cells, Cultured; Colforsin; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Humans; Intraocular Pressure; Isoproterenol; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, Adrenergic, beta-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Trabecular Meshwork | 2012 |
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Membrane Proteins; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; Xanthines | 2012 |
Interaction between serotoninergic-and β-adrenergic receptors signaling pathways in rat femoral artery.
Topics: Animals; Colforsin; Femoral Artery; Isoproterenol; Male; Models, Animal; Peripheral Arterial Disease; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Signal Transduction; Vasoconstrictor Agents; Vasodilator Agents | 2012 |
Β-adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis.
Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Animals; Antigens, Differentiation; Apoptosis; Brefeldin A; Caspase 12; Caspase Inhibitors; Cells, Cultured; Cinnamates; Colforsin; eIF-2 Kinase; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Heat-Shock Proteins; Isoproterenol; Male; Mice; Myocytes, Cardiac; Phosphorylation; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction; Thapsigargin; Thiourea; Transcription Factor CHOP | 2012 |
Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix.
Topics: Actins; Adrenergic beta-Agonists; Animals; Carbachol; Cervix Uteri; Cholinergic Agonists; Colforsin; Female; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Oxytocin; Pregnancy; Prostaglandins F; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Serotonin; Uterine Contraction; Uterus | 2012 |
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies.
Topics: Adrenergic beta-Agonists; Alginates; Barium; Biocompatible Materials; Calcium; Capsules; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colforsin; Glucuronic Acid; Hexuronic Acids; Humans; Intestine, Small; Isoproterenol; Microscopy, Confocal; Microspheres; Models, Biological; Neuroendocrine Tumors; Serotonin; Spheroids, Cellular; Time Factors | 2012 |
Modulation of PAR(1) signalling by benzimidazole compounds.
Topics: Benzimidazoles; Calcium; Cell Line; Colforsin; Cyclic AMP; Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Receptor, PAR-1; Signal Transduction | 2012 |
Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat.
Topics: Acetates; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Agonists; Animals; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Female; Heart Rate; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Organ Specificity; p-Hydroxyamphetamine; Rats; Rats, Sprague-Dawley; Substrate Specificity; Urinary Bladder; Urinary Bladder, Overactive | 2012 |
Adenylyl cyclase 2 selectively couples to E prostanoid type 2 receptors, whereas adenylyl cyclase 3 is not receptor-regulated in airway smooth muscle.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bronchi; Caveolins; Cell Line, Transformed; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; HEK293 Cells; Humans; Isoproterenol; Male; Mice; Muscle, Smooth; Myocytes, Smooth Muscle; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction | 2012 |
Neuropeptide Y potentiates beta-adrenergic stimulation of lipolysis in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Carrier Proteins; Colforsin; Energy Metabolism; Enzyme Activators; Fatty Acid Synthases; Gene Expression; Glycerol; Isoproterenol; Lipase; Lipolysis; Mice; Neuropeptide Y; Perilipin-1; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Second Messenger Systems; Stearoyl-CoA Desaturase; Sterol Esterase | 2012 |
Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Bisoprolol; Catecholamines; Child; Clenbuterol; Colforsin; Cyclic AMP; Female; Heart Failure; Heart-Assist Devices; Humans; Isoproterenol; Male; Middle Aged; Myocardium; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Young Adult | 2012 |
Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells.
Topics: Adenylyl Cyclases; Amino Acid Substitution; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; GTP-Binding Proteins; Humans; Interleukin-6; Isoproterenol; Promoter Regions, Genetic; Protein Glutamine gamma Glutamyltransferase 2; Rats; Signal Transduction; Transglutaminases | 2013 |
Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Carbazoles; Cations, Divalent; Cerebral Arteries; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Endothelium, Vascular; Female; Gene Expression Regulation; Isoproterenol; Nickel; Nifedipine; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Increased beta2-adrenoceptors in doxorubicin-induced cardiomyopathy in rat.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Cardiotonic Agents; Colforsin; Doxorubicin; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Survival Analysis | 2013 |
Agonist-induced desensitization of human β3-adrenoceptors expressed in human embryonic kidney cells.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; CHO Cells; Colforsin; Cricetulus; Cyclic AMP; HEK293 Cells; Humans; Isoproterenol; Receptors, Adrenergic, beta-3 | 2013 |
Cross-talk from β-adrenergic receptors modulates α2A-adrenergic receptor endocytosis in sympathetic neurons via protein kinase A and spinophilin.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Arrestins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Endocytosis; Enzyme Activation; Epinephrine; Fibroblasts; Isoproterenol; Mice; Microfilament Proteins; Models, Biological; Mutant Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Binding; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Signal Transduction; Sympathetic Nervous System | 2013 |
β-Adrenergic receptors activate exchange protein directly activated by cAMP (Epac), translocate Munc13-1, and enhance the Rab3A-RIM1α interaction to potentiate glutamate release at cerebrocortical nerve terminals.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Isoproterenol; Mice; Naphthalenes; Nerve Tissue Proteins; Presynaptic Terminals; Protein Transport; rab3A GTP-Binding Protein; Receptors, Adrenergic, beta; Synaptic Membranes; Synaptic Transmission; Type C Phospholipases | 2013 |
Broad-scale phosphoprotein profiling of beta adrenergic receptor (β-AR) signaling reveals novel phosphorylation and dephosphorylation events.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Animals; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Embryonic Stem Cells; Isoproterenol; MAP Kinase Signaling System; Phosphorylation; Protein Kinases; Receptors, Adrenergic, beta | 2013 |
cAMP-PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3-Orai1 complex.
Topics: Adrenergic beta-Agonists; Azepines; Calcium; Calcium Channels; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Isoproterenol; Membrane Microdomains; Niacinamide; ORAI1 Protein; Phosphodiesterase 4 Inhibitors; Protein Binding; Protein Kinase Inhibitors; Pyrroles; Small-Conductance Calcium-Activated Potassium Channels | 2014 |
Exchange protein directly activated by cAMP mediates slow delayed-rectifier current remodeling by sustained β-adrenergic activation in guinea pig hearts.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Delayed Rectifier Potassium Channels; Egtazic Acid; Guanine Nucleotide Exchange Factors; Guinea Pigs; Hypertrophy, Left Ventricular; Imidazoles; Ion Channel Gating; Isoproterenol; Myocytes, Cardiac; NFATC Transcription Factors; Patch-Clamp Techniques; Potassium; Propanolamines; Receptors, Adrenergic, beta-1; RNA Interference; RNA, Small Interfering; Second Messenger Systems | 2014 |
Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea.
Topics: Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Bronchodilator Agents; Bumetanide; Calcium; Carbachol; Carbonates; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Female; Ferrets; Ion Transport; Isoproterenol; Mucociliary Clearance; Mucus; Nitrobenzoates; Sodium Potassium Chloride Symporter Inhibitors; Trachea | 2014 |
Mucosa of murine detrusor impairs β2 -adrenoceptor-mediated relaxation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Aminophenols; Animals; Colforsin; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mucous Membrane; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Sulfonamides; Urinary Bladder; Vasodilator Agents | 2015 |
Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Electric Stimulation; Gene Expression Regulation; Heart Ventricles; Isoproterenol; Male; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Signal Transduction; Tissue Culture Techniques; TRPM Cation Channels | 2014 |
β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium Signaling; Cardiomyopathy, Hypertrophic; Cats; Cell Line, Tumor; Colforsin; Cyclic AMP; G-Protein-Coupled Receptor Kinases; Genes, Reporter; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; HEK293 Cells; Humans; Indoles; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Myocardial Contraction; Pyrrolidines; Receptors, Adrenergic, beta; Receptors, Vasopressin; Recombinant Fusion Proteins; Rolipram; Second Messenger Systems | 2014 |
Pyocyanin inhibits both nitric oxide-dependent and -independent relaxation in porcine coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diethylamines; Dinoprost; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pseudomonas aeruginosa; Pyocyanine; Swine; Vasodilation | 2015 |
β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor.
Topics: Aminophenols; Animals; Carbachol; Cholinergic Agonists; Colforsin; Homozygote; Imidazoles; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucous Membrane; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-2; Sulfonamides; Urinary Bladder | 2015 |
Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
Topics: Aged; Colforsin; Female; Gene Expression Regulation; Humans; Isoproterenol; KCNQ Potassium Channels; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta; Urinary Bladder; Urinary Bladder Neck Obstruction | 2015 |
Contractile function of smooth muscle retained after overnight storage.
Topics: Animals; Carbachol; Colforsin; Endothelium, Vascular; Isoproterenol; Male; Models, Animal; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Preservation | 2015 |
Comprehensive analysis of chemokine-induced cAMP-inhibitory responses using a real-time luminescent biosensor.
Topics: Adenylyl Cyclases; Biosensing Techniques; Cells, Cultured; Chemokines; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Isoproterenol; Kinetics; Receptors, CXCR4 | 2016 |
H2S induces vasoconstriction of rat cerebral arteries via cAMP/adenylyl cyclase pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Cerebral Arteries; Colforsin; Cyclic AMP; Endothelium; Hydrogen Sulfide; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sulfides; Vasoconstriction | 2015 |
Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells.
Topics: Adrenergic beta-Agonists; Animals; Cell Line, Tumor; Colforsin; Dinoprostone; Gastric Mucosa; Gene Expression Profiling; Ghrelin; Hormones; Immunohistochemistry; Isoproterenol; Lactic Acid; Mice; Mice, Transgenic; Muscarine; Muscarinic Agonists; Oxytocics; Oxytocin; Palmitates; Receptor, Muscarinic M4; Receptors, Adrenergic, beta-1; Receptors, G-Protein-Coupled; Receptors, Oxytocin; Receptors, Prostaglandin E, EP4 Subtype; Receptors, Somatostatin; RNA, Messenger; Sequence Analysis, RNA; Somatostatin; Tryptophan | 2016 |
Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Western; Colforsin; Cyclic AMP; Insulin; Insulin Resistance; Isoproterenol; Male; Obesity; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Suppressor Protein p53 | 2016 |
[Effect of Kanli Granule on Myocardial Mechanics in Pressure Overload Induced Diastolic Heart Failure Rats].
Topics: Animals; Colforsin; Drugs, Chinese Herbal; Heart; Heart Failure, Diastolic; Isoproterenol; Male; Random Allocation; Rats; Rats, Wistar | 2016 |
Somatic and dendritic perforated-patch recordings reveal b-adrenergic receptor-induced depolarization in medial prefrontal cortex pyramidal neurons.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Biophysics; Bronchodilator Agents; Colforsin; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Metoprolol; Patch-Clamp Techniques; Prefrontal Cortex; Protein Kinase Inhibitors; Pyramidal Cells; Rats; Receptors, Adrenergic, beta; Sodium Channel Blockers; Tetrodotoxin | 2016 |
Dendritic diameter influences the rate and magnitude of hippocampal cAMP and PKA transients during β-adrenergic receptor activation.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendrites; Hippocampus; Isoproterenol; Mice; Models, Neurological; Phosphodiesterase Inhibitors; Phosphorylation; Receptors, Adrenergic, beta; Signal Transduction | 2017 |
Tunicamycin-Induced Alterations in the Vasorelaxant Response in Organ-Cultured Superior Mesenteric Arteries of Rats.
Topics: Acetylcholine; Animals; Anti-Bacterial Agents; Colforsin; Cromakalim; Endoplasmic Reticulum Stress; Endothelium, Vascular; Heat-Shock Proteins; Isoproterenol; Male; Mesenteric Artery, Superior; Nitric Oxide; Nitroprusside; Organ Culture Techniques; Rats, Wistar; Tunicamycin; Vasodilation; Vasodilator Agents | 2016 |
Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Fluorescence Resonance Energy Transfer; Isoproterenol; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac | 2016 |
cAMP attenuates angiotensin-II-induced Egr-1 expression via PKA-dependent signaling pathway in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Early Growth Response Protein 1; Gene Expression Regulation; Intracellular Space; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; Rats; Signal Transduction | 2017 |
Exclusion of alternative exon 33 of Ca
Topics: Action Potentials; Alternative Splicing; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Electrophysiological Phenomena; Heart Failure; Isoproterenol; Long QT Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Nifedipine; Rats; Sequence Deletion; Tachycardia; Ventricular Premature Complexes | 2017 |
Concurrent activation of β
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Extracellular Signal-Regulated MAP Kinases; Female; Fenoterol; Glioma; Humans; Isoproterenol; Mice, Inbred BALB C; Mice, Nude; Proto-Oncogene Proteins c-akt; Rats; Receptors, Adrenergic, beta-2; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Serum; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Biopsy; Cell Line, Transformed; Colforsin; Humans; Isoproterenol; Neck; Retroviridae; Rosiglitazone; Telomerase; Thermogenesis; Thiazolidinediones; Tissue Donors | 2017 |
Interaction of CREB and PGC-1α Induces Fibronectin Type III Domain-Containing Protein 5 Expression in C2C12 Myotubes.
Topics: Adenosine Triphosphate; Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Fibronectins; HEK293 Cells; Humans; Isoproterenol; Mice; Muscle Fibers, Skeletal; Oxidative Phosphorylation; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Recombinant Proteins | 2018 |
Inhibition of lipolysis: A novel explanation for the hypothermic actions of acetaminophen in non-febrile rodents.
Topics: 3T3-L1 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Acetaminophen; Adipocytes; Adrenergic beta-Agonists; Aminopyrine; Animals; Antipyretics; Antipyrine; Body Temperature; Cell Differentiation; Colforsin; Isoproterenol; Lipolysis; Mice; Rats; Rats, Wistar | 2020 |
Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model.
Topics: Animals; Carbachol; Colforsin; Cystic Fibrosis; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Ferrets; Isoproterenol; Mucociliary Clearance; Muscle Contraction; Muscle, Smooth; Swine | 2021 |
Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II.
Topics: Adaptor Proteins, Signal Transducing; Antigens, Neoplasm; Colforsin; Cyclic AMP-Dependent Protein Kinases; Female; HEK293 Cells; HeLa Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoproterenol; Pregnancy | 2022 |
Rhinovirus C15 Attenuates Relaxation and cAMP Production in Human Airways and Smooth Muscle.
Topics: Adult; Child; Colforsin; Enterovirus Infections; Formoterol Fumarate; Humans; Isoproterenol; Lung; Muscle Relaxation; Muscle, Smooth; Rhinovirus | 2023 |