isoproterenol and clozapine

isoproterenol has been researched along with clozapine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's2 (9.52)18.2507
2000's5 (23.81)29.6817
2010's10 (47.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Clement-Cormier, YC; Robison, GA1
Clement-Cormier, YC; Greengard, P; Kebabian, JW; Petzold, GL1
Ahn, HS; Demirjian, C; Makman, MH; Mishra, RK1
Nobrega, JN; Wiener, NI1
De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM1
Carson, MJ; Neal, MJ; Sutcliffe, JG; Thomas, EA1
Cabras, T; Isola, M; Loy, F; Puxeddu, R; Riva, A; Testa Riva, F1
Andressen, KW; Krobert, KA; Levy, FO1
Ekström, J; Godoy, T; Riva, A2
Gabeler, EE; van Miltenburg, AJ1

Reviews

1 review(s) available for isoproterenol and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for isoproterenol and clozapine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Adenylate cyclase from various dopaminergic areas of the brain and the action of antipsychotic drugs.
    Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18

    Topics: Adenylyl Cyclases; Amygdala; Animals; Antipsychotic Agents; Apomorphine; Brain; Caudate Nucleus; Clozapine; Dopamine; Fluphenazine; Isoproterenol; Loxapine; Median Eminence; Norepinephrine; Olfactory Bulb; Rats

1977
Chemistry of dopamine receptors.
    Advances in neurology, 1975, Volume: 9

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Butyrophenones; Caudate Nucleus; Chemical Phenomena; Chemistry; Clozapine; Dopamine; Isoproterenol; Olfactory Bulb; Phenothiazines; Phenylephrine; Rats; Receptors, Drug

1975
Catecholamine-sensitive adenylate cyclase in frontal cortex of primate brain.
    Brain research, 1976, Nov-12, Volume: 116, Issue:3

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Calcium; Catecholamines; Cerebral Cortex; Clozapine; Dopamine; Drug Combinations; Fluphenazine; Frontal Lobe; Guanosine Triphosphate; Haloperidol; Haplorhini; Isoproterenol; Macaca mulatta; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Dopamine; Sodium Fluoride; Time Factors

1976
Effects of catecholamine agonist and antagonist drugs on acute stomach ulceration induced by medial hypothalamic lesions in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Amphetamine; Animals; Catecholamines; Chlorpromazine; Clozapine; Desipramine; Haloperidol; Hypothalamus, Middle; Isoproterenol; Male; Pargyline; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stomach Ulcer

1983
Nature of 5-HT1-like receptors mediating depressor responses in vagosympathectomized rats; close resemblance to the cloned 5-ht7 receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: 5-Methoxytryptamine; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Ergolines; Heart Rate; Isoproterenol; Lisuride; Male; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy

1997
Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Dec-09, Volume: 94, Issue:25

    Topics: Allosteric Regulation; Allosteric Site; Animals; Cats; Cell Line; Cerebrosides; Clozapine; Colforsin; Cyclic AMP; GTP-Binding Proteins; HeLa Cells; Humans; Isoproterenol; Oleic Acids; Phosphatidylinositols; Rats; Receptors, Serotonin; Serotonin; Signal Transduction

1997
Serous and mucous cells of human submandibular salivary gland stimulated in vitro by isoproterenol, carbachol and clozapine: an LM, TEM, and HRSEM Study.
    European journal of morphology, 2003, Volume: 41, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Antipsychotic Agents; Biopsy; Carbachol; Clozapine; Female; Humans; Isoproterenol; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Middle Aged; Mucous Membrane; Muscarinic Agonists; Serous Membrane; Submandibular Gland

2003
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium

2006
N-Desmethylclozapine exerts dual and opposite effects on salivary secretion in the rat.
    European journal of oral sciences, 2010, Volume: 118, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Denervation; Drug Synergism; Female; Isoproterenol; Muscarinic Agonists; Parotid Gland; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Saliva; Salivation; Secretory Rate; Submandibular Gland

2010
Atypical antipsychotics--effects of amisulpride on salivary secretion and on clozapine-induced sialorrhea.
    Oral diseases, 2012, Volume: 18, Issue:7

    Topics: Amisulpride; Amylases; Animals; Antipsychotic Agents; Autonomic Agents; Bethanechol; Clozapine; Denervation; Female; Isoproterenol; Methacholine Chloride; Parasympathetic Nervous System; Parotid Gland; Raclopride; Rats; Rats, Sprague-Dawley; Saliva; Salivation; Sialorrhea; Submandibular Gland; Substance P; Sulpiride; Sympathetic Nervous System

2012
Complete AV-block secondary to lithium-clozapine therapy and relapsing multiple sclerosis in a bipolar patient.
    BMJ case reports, 2011, Dec-01, Volume: 2011

    Topics: Antipsychotic Agents; Atrioventricular Block; Bipolar Disorder; Cardiotonic Agents; Clozapine; Female; Humans; Isoproterenol; Lithium; Middle Aged; Multiple Sclerosis; Pacemaker, Artificial; Recurrence

2011