isoproterenol and carvedilol

isoproterenol has been researched along with carvedilol in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (11.11)	18.7374
1990's	9 (16.67)	18.2507
2000's	16 (29.63)	29.6817
2010's	18 (33.33)	24.3611
2020's	5 (9.26)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Gagnon, R; Slivjak, MJ; Smith, EF	1
Carugo, S; Cattaneo, BM; Giannattasio, C; Grassi, G; Mancia, G; Mangoni, AA; Seravalle, G; Zanchetti, A	1
Gellai, M; Nichols, AJ; Ruffolo, RR	1
Bartsch, W; Böhm, E; Borbe, HO; Kling, L; Martin, U; Müller-Beckmann, B; Sponer, G; Strein, K	1
Bartsch, W; Böhm, E; Müller-Beckmann, B; Sponer, G; Strein, K	1
Colindres, RE; Cubeddu, LX; Fuenmayor, N; Powell, JR; Varin, F; Villagra, VG	2
Ashton, DJ; Hieble, JP; Nichols, AJ; Ruffolo, RR; Sulpizio, AC	1
Komori, K; Nagao, T; Seki, N; Suzuki, H	1
Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B	1
Irlbeck, M; Zimmer, HG	1
Guy, S; McDermott, BJ; Riddell, JG; Shanks, RG; Tham, TC	1
Böhm, M; Ettelbrück, S; Flesch, M; Knorr, A; Maack, C; Paul, M; Pinto, YM; Teisman, AC; van Gilst, WH; Zolk, O	1
Abuin, L; Cotecchia, S; Lattion, A; Nenniger-Tosato, M	1
Grace, AA; Kaumann, AJ; Lowe, MD	1
Ikeda, U; Kurosaki, K; Maeda, Y; Shimada, K	1
Higaki, J; Kotani, N; Moriguchi, A; Nakagami, H; Ogihara, T	1
Chen, J; Christopher, TA; Gao, F; Gu, J; Lopez, BL; Lysko, P; Ma, XL; Ohlstein, EH; Ruffolo, RR; Yue, TL	1
Böhm, M; Cremers, B; Ettelbrück, S; Flesch, M; Maack, C; Rosenkranz, S; Schlüter, KD; Zolk, O	1
Iida, K; Kawano, S; Masumi, T; Nishi, I; Yamaguchi, I	1
Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Schwinger, RH	1
Ishikawa, Y; Sasaki, T; Uechi, M; Ueno, K; Yamamoto, T	1
Vita, JA	1
Böhm, M; Finkler, N; Kindermann, M; Läer, S; Maack, C; Schäfers, HJ; Schaller, S; Schmidt, KI; Wuttke, H	1
Abbott, JA; Broadstone, RV; Pyle, RL; Ward, DL	1
Bøkenes, J; Osnes, JB; Qvigstad, E; Schiander, I; Sejersted, OM; Sjaastad, I; Skomedal, T; Solberg, L	1
Magovern, M; Nikolaidis, LA; Parikh, P; Poornima, I; Shannon, RP; Shen, YT	1
Boussemaere, M; Denef, C; Janssens, K; Kopka, K; Wagner, S	1
Asari, K; Hanada, K; Kawana, J; Mita, M; Ogata, H; Saito, M	1
Ahokas, RA; Bhattacharya, SK; Gerling, IC; Johnson, PL; Shahbaz, AU; Sun, Y; Weber, KT; Zhao, T; Zhao, W	1
Horst, R; Katritch, V; Liu, JJ; Stevens, RC; Wüthrich, K	1
Back, TG; Chen, PS; Chen, SR; Chua, SK; Lin, SF; Maruyama, M; Rubart-von der Lohe, M; Vembaiyan, K; Xiao, J; Zhou, Q	1
Steinberg, SF; Zhang, F	1
Andresen, BT; Chang, A; Huang, KM; Huang, Y; Jackson, EK; Kanassatega, RS; Liu, MM; Orlando, R; Parsa, C; Thakkar, A; Yeung, S	1
Akhtar, M; Khanam, R; Najmi, AK; Yadav, CH	1
Coelho, M; Correia, G; Medeiros, R; Moz, M; Ribeiro, L; Teixeira, A	1
Deng, M; Guo, X; Jiang, Z; Liu, Y; Yu, J	1
Abdel Baky, NA; Al-Mohanna, F; Bin-Dayel, AF; Fadda, LM; Mohammad, RA	1
Fang, X; Li, N; Li, Z; Sun, Y; Wu, J; Yuan, J; Zhang, M; Zhang, Y; Zhao, R; Zhou, W	1
Brill, A; Hale, GM; Jafferjee, M; Lymperopoulos, A; Marrero, C; McCrink, KA; Rodriguez, MM; Valero, TR	1
Chen, H; Chen, X; Guo, H; Niu, X; Pan, C; Yi, T	1
Hasan, W; Khan, F; Mudd, JO; Thornburg, KL; Toyooka, A; Tyrrell, C	1
Du, XJ; Hu, HY; Kiriazis, H; Lu, Q; Nguyen, MN; Puthalakath, H; Sadoshima, J; Su, Y; Wang, LN; Zhao, WB; Ziemann, M	1
Bouvier, M; Gmeiner, P; Hübner, H; Kaindl, JM; Picard, LP; Schmidt, MF; Stanek, M; Weikert, D	1
Fukuda, K; Kai, S; Matsukawa, S; Seo, H; Suzuki, K	1
Alamri, AS; Alhomrani, M; Almutiri, AH; Alsanie, WF; Alshammari, MS; Asdaq, SMB; Challa, O	1
Awad, AS; Baraka, SA; El-Demerdash, E; El-Naga, RN; Elsherbini, DA; Tolba, MF	1
Alamri, AS; Alhomrani, M; Alsanie, WF; Asdaq, SMB	1
Cao, Y; Guo, J; Huang, B; Huo, S; Li, S; Lin, L; Lv, J; Men, L; Peng, D; Peng, L; Shi, W; Wang, M; Wang, Q	1

Reviews

2 review(s) available for isoproterenol and carvedilol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Nitric oxide and vascular reactivity in African American patients with hypertension. Journal of cardiac failure, 2003, Volume: 9, Issue:5 Suppl Ni Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Black or African American; Brachial Artery; Carbazoles; Carotid Arteries; Carvedilol; Coronary Vessels; Drug Resistance; Endothelium; Glucose-6-Phosphatase; Humans; Hypertension; Inflammation; Isoproterenol; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Nitroprusside; Propanolamines; Prosencephalon; Racial Groups; Regional Blood Flow; Risk Factors; Vascular Resistance; White People	2003

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Nitric oxide and vascular reactivity in African American patients with hypertension.

Journal of cardiac failure, 2003, Volume: 9, Issue:5 Suppl Ni

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Black or African American; Brachial Artery; Carbazoles; Carotid Arteries; Carvedilol; Coronary Vessels; Drug Resistance; Endothelium; Glucose-6-Phosphatase; Humans; Hypertension; Inflammation; Isoproterenol; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Nitroprusside; Propanolamines; Prosencephalon; Racial Groups; Regional Blood Flow; Risk Factors; Vascular Resistance; White People

2003

Trials

7 trial(s) available for isoproterenol and carvedilol

Article	Year
Alpha 1-blocking properties of carvedilol during acute and chronic administration. Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Middle Aged; Phenylephrine; Prazosin; Propanolamines; Random Allocation; Vasodilator Agents	1992
Mechanism of the vasodilatory effect of carvedilol in normal volunteers: a comparison with labetalol. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11 Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Carbazoles; Carvedilol; Half-Life; Heart Rate; Humans; Isoproterenol; Labetalol; Phenylephrine; Propanolamines; Random Allocation; Vasodilation	1987
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine. Drugs, 1988, Volume: 36 Suppl 6 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents	1988
Clinical pharmacology of carvedilol in normal volunteers. Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:1 Topics: Adult; Angiotensin II; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Kinetics; Labetalol; Male; Phenylephrine; Propanolamines; Random Allocation; Receptors, Adrenergic	1987
The dose dependency of the alpha- and beta-adrenoceptor antagonist activity of carvedilol in man. British journal of clinical pharmacology, 1995, Volume: 40, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Exercise; Heart Rate; Humans; Isoproterenol; Labetalol; Male; Phenylephrine; Propanolamines; Vasodilator Agents	1995
Using isoproterenol stress echocardiography to predict the response to carvedilol in patients with dilated cardiomyopathy. Japanese circulation journal, 2001, Volume: 65, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Contraindications; Echocardiography; Female; Follow-Up Studies; Heart Function Tests; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Prognosis; Propanolamines; Treatment Outcome	2001
Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo. Circulation, 2004, Jun-29, Volume: 109, Issue:25 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alleles; Allosteric Site; Binding Sites; Carbazoles; Cardiac Output; Carvedilol; Cross-Over Studies; Cytochrome P-450 CYP2D6; Dobutamine; Echocardiography, Stress; Genotype; Heart Atria; Heart Rate; Humans; Inactivation, Metabolic; Isoproterenol; Male; Metoprolol; Propanolamines; Protein Binding; Receptors, Adrenergic, beta; Up-Regulation	2004

Other Studies

45 other study(ies) available for isoproterenol and carvedilol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Single and repeated doses of the vasodilator/beta-adrenergic antagonist, carvedilol, block cirazoline- and isoproterenol-mediated hemodynamic responses in the conscious rat. Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Hemodynamics; Imidazoles; Isoproterenol; Male; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents	1992
Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent, carvedilol. Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Arteries; Azepines; Calcium Channel Blockers; Carbazoles; Carvedilol; Consciousness; Dose-Response Relationship, Drug; Hemodynamics; Isoproterenol; Male; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstrictor Agents; Vasodilation	1991
Pharmacological characteristics of the stereoisomers of carvedilol. European journal of clinical pharmacology, 1990, Volume: 38 Suppl 2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Carbazoles; Carvedilol; Decerebrate State; Heart Rate; Hypertension; In Vitro Techniques; Isoproterenol; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Propanolamines; Rabbits; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereoisomerism	1990
Pharmacological profile of carvedilol as a beta-blocking agent with vasodilating and hypotensive properties. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Dogs; Hemodynamics; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Propanolamines; Rabbits; Rats; Sympathomimetics; Vasodilator Agents	1987
The interaction of the enantiomers of carvedilol with alpha 1- and beta 1-adrenoceptors. Chirality, 1989, Volume: 1, Issue:4 Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Carbazoles; Carvedilol; Decerebrate State; Guinea Pigs; Heart; Heart Rate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Propanolamines; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereoisomerism	1989
Alpha and beta adrenoceptor blocking action of carvedilol in the canine mesenteric artery and vein. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dogs; Electrophysiology; Evoked Potentials; Female; Guinea Pigs; Isoproterenol; Male; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Propanolamines; Synaptic Transmission; Yohimbine	1988
Acute effects of catecholamines on function of the rat right heart. Cardiovascular research, 1993, Volume: 27, Issue:12 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Catecholamines; Female; Heart Rate; Isoproterenol; Metoprolol; Norepinephrine; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Ventricular Function, Right	1993
Beta-adrenergic signal transduction following carvedilol treatment in hypertensive cardiac hypertrophy. Cardiovascular research, 1998, Volume: 40, Issue:1 Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Genetically Modified; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Colforsin; Down-Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanylyl Imidodiphosphate; Heart Rate; Isoproterenol; Male; Neuropeptide Y; Pertussis Toxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Virulence Factors, Bordetella	1998
Constitutively active mutants of the beta1-adrenergic receptor. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Betaxolol; Carbazoles; Carvedilol; Cell Line; Cyclic AMP; Epinephrine; Humans; Imidazoles; Isoproterenol; Labetalol; Point Mutation; Practolol; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Timolol	1999
Blockade of putative beta4- and beta1-adrenoceptors by carvedilol in ferret myocardium. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Ferrets; Heart Atria; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Propanolamines; Receptors, Adrenergic, beta; Sinoatrial Node	1999
Carvedilol stimulates nitric oxide synthesis in rat cardiac myocytes. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atenolol; Carbazoles; Carvedilol; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Guanidines; Heart; Interleukin-1; Isoproterenol; Muscle Proteins; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nucleic Acid Synthesis Inhibitors; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Recombinant Proteins	2000
Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbazoles; Cardiovascular System; Carvedilol; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Norepinephrine; Phenylephrine; Posture; Propanolamines; Systole; Tilt-Table Test	2000
Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model. European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Bisoprolol; Carbazoles; Cardiovascular Agents; Carvedilol; Creatine Kinase; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Lipid Peroxidation; Male; Membrane Lipids; Myocardial Ischemia; Myocardium; Peroxidase; Propanolamines; Rabbits; Reperfusion Injury; Ventricular Pressure	2000
Differential effects of carvedilol and metoprolol on isoprenaline-induced changes in beta-adrenoceptor density and systolic function in rat cardiac myocytes. Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Cell Size; Cells, Cultured; Electric Stimulation; Guanylyl Imidodiphosphate; Isoproterenol; Male; Metoprolol; Microscopy, Phase-Contrast; Myocardium; Propanolamines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Regression Analysis	2001
Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium. British journal of pharmacology, 2001, Volume: 133, Issue:8 Topics: Adrenergic beta-Antagonists; Benzopyrans; Binding, Competitive; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Female; Guanylyl Imidodiphosphate; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Propanolamines; Substrate Specificity; Sympathetic Nervous System; Sympathomimetics; Thermodynamics	2001
Cardiovascular and renal effects of carvedilol in dogs with heart failure. The Journal of veterinary medical science, 2002, Volume: 64, Issue:6 Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Dog Diseases; Dogs; Echocardiography; Female; Glomerular Filtration Rate; Heart Rate; Isoproterenol; Kidney; Male; Mitral Valve Insufficiency; Phenylephrine; Propanolamines; Ventricular Remodeling	2002
Hemodynamic effects of orally administered carvedilol in healthy conscious dogs. American journal of veterinary research, 2005, Volume: 66, Issue:4 Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Dogs; Heart Failure; Heart Rate; Hemodynamics; Isoproterenol; Phenylephrine; Propanolamines; Pulmonary Wedge Pressure; Random Allocation	2005
Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure. European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Failure; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardial Infarction; Norepinephrine; Papillary Muscles; Phenylephrine; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Vasoconstrictor Agents; Vasodilator Agents	2005
The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy. Journal of the American College of Cardiology, 2006, May-02, Volume: 47, Issue:9 Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Metoprolol; Myocardium; Propanolamines; Regional Blood Flow; Ventricular Function, Left	2006
Beta1-adrenoceptors in rat anterior pituitary may be constitutively active. Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels. Endocrinology, 2008, Volume: 149, Issue:5 Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Animals; Carbazoles; Carvedilol; Cell Aggregation; Cells, Cultured; Cyclic AMP; Drug Inverse Agonism; Enzyme Activation; Imidazoles; Isoproterenol; Male; Pertussis Toxin; Pituitary Gland, Anterior; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Substrate Specificity	2008
Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers. European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3 Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Cardiomegaly; Carvedilol; Cyclic AMP; Disease Models, Animal; Heart Failure; Heart Rate; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors; Ventricular Function, Left	2008
Calcium and zinc dyshomeostasis during isoproterenol-induced acute stressor state. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Calcium; Capillary Permeability; Carbazoles; Carvedilol; Endothelium; Homeostasis; In Vitro Techniques; Isoproterenol; Male; Metallothionein; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Necrosis; Oxidative Stress; Propanolamines; Quercetin; Rats; Rats, Sprague-Dawley; Sarcolemma; Stress, Physiological; Superoxide Dismutase; Zinc	2011
Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science (New York, N.Y.), 2012, Mar-02, Volume: 335, Issue:6072 Topics: Adrenergic beta-2 Receptor Agonists; Arrestins; beta-Arrestins; Binding Sites; Carbazoles; Carvedilol; Cytoplasm; Drug Partial Agonism; Fluorine; Isoetharine; Isoproterenol; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Propanolamines; Protein Conformation; Protein Structure, Secondary; Receptors, Adrenergic, beta-2; Signal Transduction; Structure-Activity Relationship	2012
Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations. Heart rhythm, 2013, Volume: 10, Issue:1 Topics: Action Potentials; Analysis of Variance; Animals; Calcium; Carbazoles; Carvedilol; Heart Ventricles; Isoproterenol; Long QT Syndrome; Membrane Potentials; Mice; Morpholines; Propanolamines; Rabbits	2013
S49G and R389G polymorphisms of the β₁-adrenergic receptor influence signaling via the cAMP-PKA and ERK pathways. Physiological genomics, 2013, Dec-01, Volume: 45, Issue:23 Topics: Blotting, Western; Carbazoles; Carvedilol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Isoproterenol; MAP Kinase Signaling System; Membrane Microdomains; Mutation, Missense; Plasmids; Propanolamines; Receptors, Adrenergic, beta-1	2013
Prevention of skin carcinogenesis by the β-blocker carvedilol. Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Antagonists; Animals; Anticarcinogenic Agents; Atenolol; Carbazoles; Carvedilol; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Isoproterenol; Mice; Mutation; Neoplasm Transplantation; Propanolamines; Skin Neoplasms; Transcription Factor AP-1	2015
Cardioprotective role of H₃R agonist imetit on isoproterenol-induced hemodynamic changes and oxidative stress in rats. Toxicology mechanisms and methods, 2015, Volume: 25, Issue:4 Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Height; Body Weight; Carbazoles; Cardiotonic Agents; Carvedilol; Heart Diseases; Heart Rate; Hemodynamics; Histamine Agonists; Humans; Imidazoles; Isoproterenol; Male; Myocardium; Oxidative Stress; Propanolamines; Rats; Rats, Wistar; Thiourea	2015
Antiproliferative effects of β-blockers on human colorectal cancer cells. Oncology reports, 2015, Volume: 33, Issue:5 Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Carbazoles; Carvedilol; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epinephrine; HT29 Cells; Humans; Isoproterenol; Norepinephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Signal Transduction	2015
Capillary electrophoretic enantioseparation of basic drugs using a new single-isomer cyclodextrin derivative and theoretical study of the chiral recognition mechanism. Journal of separation science, 2016, Volume: 39, Issue:9 Topics: Brompheniramine; Carbazoles; Carvedilol; Chlorpheniramine; Clenbuterol; Cyclodextrins; Econazole; Electrophoresis, Capillary; Isoproterenol; Miconazole; Molecular Structure; Pheniramine; Procaterol; Propanolamines; Stereoisomerism; Terbutaline; Tropanes	2016
Effect of aliskiren and carvedilol on expression of Ca(2+)/calmodulin-dependent protein kinase II δ-subunit isoforms in cardiac hypertrophy rat model. Toxicology mechanisms and methods, 2016, Volume: 26, Issue:2 Topics: Amides; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carbazoles; Cardiomegaly; Carvedilol; Creatine Kinase, MB Form; Disease Models, Animal; Drug Therapy, Combination; Fumarates; Heart; Isoproterenol; Male; Myocardium; Organ Size; Propanolamines; Protein Isoforms; Rats, Wistar; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Troponin T	2016
Single-molecule imaging reveals the stoichiometry change of β2-adrenergic receptors by a pharmacological biased ligand. Chemical communications (Cambridge, England), 2016, Jun-04, Volume: 52, Issue:44 Topics: Carbazoles; Carvedilol; Green Fluorescent Proteins; HEK293 Cells; Humans; Isoproterenol; Ligands; Microscopy, Fluorescence; Optical Imaging; Propanolamines; Propranolol; Receptors, Adrenergic, beta-2; Stereoisomerism	2016
β Pharmacogenomics, 2016, Volume: 17, Issue:15 Topics: Animals; beta-Arrestins; Carbazoles; Carvedilol; Cells, Cultured; Isoproterenol; Myocytes, Cardiac; Polymorphism, Genetic; Propanolamines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Tropism	2016
A novel in situ strategy for the preparation of a β-cyclodextrin/polydopamine-coated capillary column for capillary electrochromatography enantioseparations. Journal of separation science, 2017, Volume: 40, Issue:12 Topics: beta-Cyclodextrins; Capillary Electrochromatography; Carbazoles; Carvedilol; Epinephrine; Indoles; Isoproterenol; Norepinephrine; Polymers; Propanolamines; Stereoisomerism; Terbutaline; Tryptophan; Verapamil	2017
The neuropeptide galanin promotes an anti-thrombotic phenotype on endocardial endothelial cells from heart failure patients. Autonomic neuroscience : basic & clinical, 2017, Volume: 206 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antithrombins; Carbazoles; Carvedilol; Cells, Cultured; Endothelial Cells; Galanin; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Male; Middle Aged; Neuropeptide Y; Phenotype; Propanolamines; Propranolol; Protein Multimerization; Thrombin	2017
Stimulation of β-adrenoceptors up-regulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway. British journal of pharmacology, 2019, Volume: 176, Issue:14 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bcl-2-Like Protein 11; Cardiovascular Diseases; Carvedilol; Cell Line; Dose-Response Relationship, Drug; Galectin 3; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta-3; Signal Transduction; Up-Regulation	2019
Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias. Journal of medicinal chemistry, 2019, 05-23, Volume: 62, Issue:10 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; beta-Arrestins; Carvedilol; Catechols; Drug Design; GTP-Binding Proteins; Humans; Hydrogen Bonding; Indicators and Reagents; Isoproterenol; Ligands; Mice; Models, Molecular; Molecular Dynamics Simulation; Salmeterol Xinafoate	2019
Activation of the β-adrenergic receptor exacerbates lipopolysaccharide-induced wasting of skeletal muscle cells by increasing interleukin-6 production. PloS one, 2021, Volume: 16, Issue:5 Topics: Animals; Carvedilol; CCAAT-Enhancer-Binding Protein-delta; Epinephrine; Gene Expression Regulation; Humans; Interleukin-6; Isoproterenol; Lipopolysaccharides; Mice; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myoblasts; NF-kappa B; Nitriles; Norepinephrine; Oxazolidinones; Receptors, Adrenergic, beta; SKP Cullin F-Box Protein Ligases; STAT3 Transcription Factor; Sulfones	2021
Cytoprotective Potential of Aged Garlic Extract (AGE) and Its Active Constituent, S-allyl-l-cysteine, in Presence of Carvedilol during Isoproterenol-Induced Myocardial Disturbance and Metabolic Derangements in Rats. Molecules (Basel, Switzerland), 2021, May-27, Volume: 26, Issue:11 Topics: Animals; Antioxidants; Carvedilol; Catalase; Creatine Kinase, MB Form; Cysteine; Female; Garlic; Heart; Hemodynamics; Isoproterenol; L-Lactate Dehydrogenase; Myocardium; Necrosis; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2021
Rosuvastatin and low-dose carvedilol combination protects against isoprenaline-induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO-1 signalling. Clinical and experimental pharmacology & physiology, 2021, Volume: 48, Issue:10 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anticholesteremic Agents; Apoptosis; Carvedilol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Heme Oxygenase (Decyclizing); Isoproterenol; Male; Myocardial Infarction; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rosuvastatin Calcium; Signal Transduction	2021
Cardioprotective Potential of Garlic Oil and Its Active Constituent, Diallyl Disulphide, in Presence of Carvedilol during Chronic Isoprenaline Injection-Mediated Myocardial Necrosis in Rats. Molecules (Basel, Switzerland), 2021, Aug-25, Volume: 26, Issue:17 Topics: Allyl Compounds; Animals; Antioxidants; Cardiotonic Agents; Carvedilol; Catalase; Disease Models, Animal; Disulfides; Garlic; Heart; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha	2021
IL-6/gp130/STAT3 signaling contributed to the activation of the PERK arm of the unfolded protein response in response to chronic β-adrenergic stimulation. Free radical biology & medicine, 2023, Aug-20, Volume: 205 Topics: Adrenergic Agents; Animals; Carvedilol; Cytokine Receptor gp130; Endoribonucleases; Interleukin-6; Isoproterenol; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Receptors, Adrenergic; Unfolded Protein Response	2023