isoproterenol and betaxolol

isoproterenol has been researched along with betaxolol in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199013 (33.33)18.7374
1990's16 (41.03)18.2507
2000's7 (17.95)29.6817
2010's3 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aué, GH; Bultsma, T; IJzerman, AP; Linschoten, MR; Timmerman, H1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Tran, VT1
Bonin, H; Bouvier, M; Frielle, T; Nantel, F; Nguyen, CT; Suzuki, T; Valiquette, M1
Irvine, NA; Lipworth, BJ; McDevitt, DG3
Hugues, FC; Le Jeunne, C; Munera, Y1
Chuang, DM; Hough, C1
Goldie, RG; Henry, PJ1
de Dieuleveult, C; Pinaud, M; Queinnec, MC; Souron, R1
Barnes, PJ; Meldrum, LA; Rhoden, KJ1
Riddell, JG; Shanks, RG1
Amlaiky, N; Leclerc, G1
Bevan, JA; McPherson, GA1
Cavero, I; Hicks, PE; Langer, SZ; Lefevre-Borg, F; Manoury, P1
Nathanson, JA1
Duval, N; Eon, MT; Langer, SZ; Lee, CR; Petruzzo, P1
Vidal-Beretervide, K1
Bojanic, D; Jansen, JD; Nahorski, SR; Zaagsma, J1
Anlauf, M; Bock, KD; Brodde, OE; Weber, F1
Curtis-Prior, PB; Tan, S1
Hartogensis, WE; Long, CS; Simpson, PC1
Benovic, JL; Higgins, NC; Kelsen, SG; Mardini, IA; Zhou, S1
Frith, S; O'Donnell, JM; Wilkins, J1
Cui, Y; Iwase, M; Kalthof, B; Sato, N; Shen, YT; Uechi, M; Vatner, DE; Vatner, SF1
Fulton, J; MacDonald, A; MacDonald, E; McLaughlin, DP; Scott, PJ1
Alda, O; Alvarez-Guerra, M; Garay, RP1
Hayashi, E; Hayashi-Morimoto, R; Ishikawa, H; Sato, Y; Yoshitomi, T1
Abuin, L; Cotecchia, S; Lattion, A; Nenniger-Tosato, M1
McLean, AJ; Milligan, G1
Chiba, S; Tsukada, M1
Crider, JY; Davis, TL; McLaughlin, M; Sharif, NA; Xu, SX2

Reviews

1 review(s) available for isoproterenol and betaxolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for isoproterenol and betaxolol

ArticleYear
The effects of time and dose on the relative beta 1- and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Betaxolol; Dose-Response Relationship, Drug; Electrocardiography; Exercise; Female; Heart Rate; Humans; Isoproterenol; Male; Time Factors

1991
Systemic effects of three beta-blocker eyedrops: comparison in healthy volunteers of beta 1- and beta 2-adrenoreceptor inhibition.
    Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Carteolol; Female; Heart Rate; Humans; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardium; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Timolol

1990
A dose-ranging study to evaluate the beta-adrenoceptor selectivity of single doses of betaxolol.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Leg; Male; Propranolol; Receptors, Adrenergic, beta; Regional Blood Flow; Tremor

1990
[Comparison in healthy volunteers of the systemic beta adrenergic receptor blockade by beta blockader eye drops].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, General; Betaxolol; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Isoproterenol; Male; Metipranolol; Ophthalmic Solutions; Placebos; Propanolamines

1989
Effects of betaxolol, propranolol, and atenolol on isoproterenol-induced beta-adrenoceptor responses.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Betaxolol; Blood Pressure; Heart Rate; Humans; Isoproterenol; Male; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vascular Resistance

1985

Other Studies

33 other study(ies) available for isoproterenol and betaxolol

ArticleYear
Quantitative evaluation of the beta 2-adrenoceptor affinity of phenoxypropanolamines and phenylethanolamines.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Dihydroalprenolol; Ethanolamines; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Muscles; Propanolamines; Receptors, Adrenergic, beta; Structure-Activity Relationship

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Human retinal pigment epithelial cells possess beta 2-adrenergic receptors.
    Experimental eye research, 1992, Volume: 55, Issue:3

    Topics: Adenylyl Cyclases; Betaxolol; Cells, Cultured; Cyclic AMP; Epinephrine; Humans; Isoproterenol; Norepinephrine; Pigment Epithelium of Eye; Pindolol; Propanolamines; Receptors, Adrenergic, beta

1992
Distinct regulation of beta 1- and beta 2-adrenergic receptors in Chinese hamster fibroblasts.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alprenolol; Animals; Betaxolol; Binding, Competitive; Cells, Cultured; Cricetinae; Cricetulus; DNA; Down-Regulation; Epinephrine; Fibroblasts; Iodocyanopindolol; Isoproterenol; Norepinephrine; Pindolol; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta; Transfection

1992
The effects of chronic dosing on the beta 1 and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:5

    Topics: Adult; Atenolol; Betaxolol; Blood Pressure; Exercise; Heart Rate; Humans; Isoproterenol; Receptors, Adrenergic, beta

1991
Differential down-regulation of beta 1- and beta 2-adrenergic receptor mRNA in C6 glioma cells.
    Biochemical and biophysical research communications, 1990, Jul-16, Volume: 170, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Cell Division; Down-Regulation; Glioma; Isoproterenol; Propanolamines; Rats; Receptors, Adrenergic, beta; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1990
Beta 1-adrenoceptors mediate smooth muscle relaxation in mouse isolated trachea.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Animals; Atenolol; Betaxolol; Cocaine; Desoxycorticosterone; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred CBA; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Trachea

1990
Inhibition of cholinergic neurotransmission in human airways by beta 2-adrenoceptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:2

    Topics: Acetylcholine; Adult; Aged; Betaxolol; Bronchi; Catecholamines; Electric Stimulation; Epinephrine; Humans; Isoproterenol; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Synaptic Transmission

1988
Synthesis and irreversible beta-adrenergic blockade with a bromoacetamido derivative of betaxolol.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Rate; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Muscle Contraction; Muscle, Smooth; Pindolol; Propanolamines; Rats; Rats, Inbred Strains

1985
Specialization in beta-1 and beta-2 adrenoceptor distribution in veins of the rabbit face: relationship to myogenic tone and sympathetic nerve innervation.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Catechols; Electrophysiology; Face; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tetrodotoxin; Veins

1987
Comparative analysis of beta-1 adrenoceptor agonist and antagonist potency and selectivity of cicloprolol, xamoterol and pindolol.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Pindolol; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta; Trachea; Xamoterol

1987
Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Heart; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship; Timolol

1988
The beta 1-adrenoceptor antagonist, betaxolol, is not released from the heart of the anaesthetized dog during sympathetic nerve stimulation.
    British journal of pharmacology, 1988, Volume: 95, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthetics; Animals; Betaxolol; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Isoproterenol; Male; Myocardium; Norepinephrine; Propanolamines; Sympathetic Nervous System

1988
Beta-blocking actions of betaxolol on the isolated rat portal vein.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Propanolamines; Rats; Rats, Inbred Strains

1988
Atypical characteristics of the beta-adrenoceptor mediating cyclic AMP generation and lipolysis in the rat adipocyte.
    British journal of pharmacology, 1985, Volume: 84, Issue:1

    Topics: Adipose Tissue; Animals; Betaxolol; Cyclic AMP; Epididymis; Fenoterol; Isoproterenol; Lipolysis; Male; Norepinephrine; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1985
Subclassification of human beta-adrenergic receptors mediating renin release.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Betaxolol; Dobutamine; Fenoterol; Humans; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin

1983
Characterization of the beta-adrenoceptor of the adipose cell of the rat.
    International journal of obesity, 1983, Volume: 7, Issue:5

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Albuterol; Animals; Betaxolol; Dose-Response Relationship, Drug; Isoproterenol; Lipolysis; Norepinephrine; Practolol; Prenalterol; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta

1983
Beta-adrenergic stimulation of cardiac non-myocytes augments the growth-promoting activity of non-myocyte conditioned medium.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Betaxolol; Cardiomegaly; Cell Division; Cells, Cultured; Culture Media, Conditioned; Cyclic AMP; DNA; Growth Substances; Heart; Isoproterenol; Myocardium; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Transforming Growth Factor beta

1993
Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
    American journal of respiratory cell and molecular biology, 1994, Volume: 11, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Glycerol; Isoproterenol; Kinetics; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Trachea

1994
Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1

    Topics: Animals; Antidepressive Agents; Betaxolol; Clenbuterol; Isoproterenol; Male; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Reinforcement, Psychology

1994
Identification and functional role of beta-adrenergic receptor subtypes in primate and rodent: in vivo versus isolated myocytes.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Pressure; Cells, Cultured; Coronary Vessels; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Papio; Pindolol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Vascular Resistance; Ventricular Function, Left; Ventricular Function, Right

1996
Effects of catecholamines on isolated human colonic smooth muscle.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analysis of Variance; Betaxolol; Catecholamines; Colon; Dose-Response Relationship, Drug; Humans; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta

1996
Celiprolol: agonist and antagonist effects at cardiac beta 1- and vascular beta 2-adrenoceptors determined under in vivo conditions in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Betaxolol; Blood Pressure; Celiprolol; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2

1997
Effects of beta antagonists on mechanical properties in rabbit ciliary artery.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1999, Volume: 237, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Carteolol; Cholinergic Agonists; Ciliary Arteries; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoproterenol; Male; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha-1; Timolol; Vasoconstriction

1999
Constitutively active mutants of the beta1-adrenergic receptor.
    FEBS letters, 1999, Sep-03, Volume: 457, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Betaxolol; Carbazoles; Carvedilol; Cell Line; Cyclic AMP; Epinephrine; Humans; Imidazoles; Isoproterenol; Labetalol; Point Mutation; Practolol; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Timolol

1999
Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Betaxolol; Binding, Competitive; Cell Line; Dihydroalprenolol; Endocytosis; Green Fluorescent Proteins; Humans; Isoproterenol; Kinetics; Ligands; Luminescent Proteins; Microscopy, Confocal; Oligopeptides; Peptides; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Tritium

2000
Vascular responses to beta-adrenoceptor subtype-selective agonists with and without endothelium in rat common carotid arteries.
    Journal of autonomic pharmacology, 2001, Volume: 21, Issue:1

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Carotid Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanolamines; Female; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Perfusion; Procaterol; Propanolamines; Rats; Rats, Wistar; Receptors, Cholinergic; Saponins; Vasodilation

2001
Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2001, Volume: 17, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Cell Line; Ciliary Body; Cyclic AMP; Drug Evaluation, Preclinical; Epithelial Cells; Female; Guinea Pigs; Humans; Intraocular Pressure; Isomerism; Isoproterenol; Macaca fascicularis; Male; Pigment Epithelium of Eye; Rats; Receptors, Adrenergic, beta

2001
Levobetaxolol (Betaxon): in vitro pharmacology, intraocular pressure lowering activity and autoradiographic localization of beta-adrenoceptors in human eyes.
    Proceedings of the Western Pharmacology Society, 2001, Volume: 44

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Betaxolol; Binding, Competitive; Epinephrine; Eye; Guinea Pigs; Humans; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Macaca fascicularis; Rats; Receptors, Adrenergic, beta

2001