isoproterenol and allopurinol

isoproterenol has been researched along with allopurinol in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199014 (37.84)18.7374
1990's11 (29.73)18.2507
2000's5 (13.51)29.6817
2010's6 (16.22)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Najarian, JS; Simmons, RL; Toledo-Pereyra, LH1
Kato, M; Kimura, H; Kuroume, T; Morikawa, A; Nakano, M; Shimizu, T1
Bast, A; de Jong, J; Onderwater, RC; Pinedo, HM; Schoofs, PR; van der Vijgh, WJ1
Pechán, I; Zimmer, HG1
Kapoor, NK; Kaul, S1
Balazs, T; Joseph, X1
Abdel-Hamid, A; Ayobe, MH; Seif-Elnasr, A1
Belloni, FL; Wolin, MS1
Buckley, BJ; Freeman, BA; Tanswell, AK1
Shimada, H; Sugino, H1
Titus, EO1
Caldarera, CM; Flamigni, F; Guarnieri, C; Lugaresi, A; Muscari, C1
Garcia, I; Segura, J; Tarrus, E1
Iwaki, K; Yonetani, Y1
Förster, W; Lohse, M; Riedel, H; Sziegoleit, W1
McMurtry, JP; Wexler, BC1
Arita, M; Fozzard, HA; Gondo, N; Hadama, T; Ono, K; Uchida, Y1
Chang, CH; Hsieh, HC; Hsieh, MJ; Kao, CL; Lin, PJ; Tsai, KT; Yao, PC1
Chang, CH; Lin, PJ; Tsai, KT; Yao, PC1
Brezina, A; Kolin, A; Mamelak, M; Pandula, E1
Babin-Chevaye, C; Franzini, E; Hakim, J; Marquetty, C; Pasquier, C; Sellak, H1
Coste, H; Delpy, E; Gouville, AC1
Cobbe, SM; Kane, KA; Martynyuk, AE; Rankin, AC1
Lee, CY; Matsumoto-Pon, J; Widdicombe, JH1
Adnot, S; Eddahibi, S; Le Monnier de Gouville, AC; Raffestin, B1
Castresana, MR; Detmer, K; Newman, WH; Wang, Z; Webb, JG1
Gao, WD; Leppo, MK; Marbán, E; Stull, LB; Szweda, L1
El-Bassossy, HM; Watson, ML1
Alam, MA; Potol, MA; Sagor, MA; Tabassum, N1
Afzal, MZ; Beatka, MJ; Haberman, M; Lam, NT; Lawlor, MW; Strande, JL; Sullivan, RT1

Reviews

2 review(s) available for isoproterenol and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A molecular biologic approach to cardiac toxicology.
    Advances in experimental medicine and biology, 1983, Volume: 161

    Topics: Acrylamides; Animals; Calcium; Cnidarian Venoms; Coronary Disease; Doxorubicin; Egtazic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Guinea Pigs; Heart; Hypoxia; Isoproterenol; Myocardium; Necrosis; Rabbits; Rats; Xanthine Oxidase

1983

Other Studies

35 other study(ies) available for isoproterenol and allopurinol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Protection of the ischemic liver by donor pretreatment before transplantation.
    American journal of surgery, 1975, Volume: 129, Issue:5

    Topics: Adenosine; Allopurinol; Animals; Dogs; Heparin; Ischemia; Isoproterenol; Liver; Liver Circulation; Liver Function Tests; Liver Transplantation; Tissue Donors; Transplantation, Homologous

1975
Effects of antiasthma drugs on superoxide anion generation from human polymorphonuclear leukocytes or hypoxanthine-xanthine oxidase system.
    International archives of allergy and applied immunology, 1991, Volume: 96, Issue:2

    Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Female; Free Radical Scavengers; Humans; Isoproterenol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phthalazines; Superoxides; Xanthine Oxidase

1991
Isolated mouse atrium as a model to study anthracycline cardiotoxicity: the role of the beta-adrenoceptor system and reactive oxygen species.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Doxorubicin; Free Radicals; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardial Contraction; Oxygen; Receptors, Adrenergic, beta; Receptors, Muscarinic; Xanthine; Xanthine Oxidase; Xanthines

1990
[The effect of allopurinol on the synthesis of adenine nucleotides and ribonucleic acid from inosine via a salvage pathway in the brain of rats].
    Ceskoslovenska neurologie a neurochirurgie, 1989, Volume: 52, Issue:6

    Topics: Adenine Nucleotides; Allopurinol; Animals; Brain; Inosine; Isoproterenol; Male; Rats; Rats, Inbred Strains; RNA

1989
Reversal of changes of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:7

    Topics: Animals; Cardiovascular Agents; Isoproterenol; Lipid Peroxides; Male; Myocardial Infarction; Oxidoreductases; Pregnenediones; Rats; Superoxide Dismutase; Xanthine Oxidase

1989
Protection against isoproterenol-induced myocardial necrosis in rats by 6-mercaptopurine and 6-thioguanine or by irradiation.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:3

    Topics: Allopurinol; Animals; Heart Diseases; Isoproterenol; Leukocytes; Leukopenia; Male; Mercaptopurine; Myocardium; Necrosis; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Thioguanine

1989
The protective effect of free radical inhibitors against catecholamine-induced toxicity.
    The Journal of the Egyptian Public Health Association, 1988, Volume: 63, Issue:5-6

    Topics: Allopurinol; Animals; Isoproterenol; Mice; Vitamin E; Zinc

1988
Superoxide anion selectively attenuates catecholamine-induced contractile tension in isolated rabbit aorta.
    The American journal of physiology, 1985, Volume: 249, Issue:6 Pt 2

    Topics: Animals; Catecholamines; Free Radicals; Isoproterenol; Mathematics; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidation-Reduction; Phenylephrine; Rabbits; Spectrophotometry; Superoxide Dismutase; Superoxides; Xanthine Oxidase

1985
Liposome-mediated augmentation of catalase in alveolar type II cells protects against H2O2 injury.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:1

    Topics: Animals; Catalase; Cell Separation; Cell Survival; Cells, Cultured; Hydrogen Peroxide; Isoproterenol; L-Lactate Dehydrogenase; Liposomes; Male; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase

1987
Effect of isoproterenol on renal uric acid excretion in rats.
    Japanese journal of pharmacology, 1987, Volume: 45, Issue:3

    Topics: Allopurinol; Animals; Blood Pressure; Isoproterenol; Male; Oxonic Acid; Phenylephrine; Rats; Rats, Inbred Strains; Uric Acid

1987
Effect of oxygen radicals and hyperoxia on rat heart ornithine decarboxylase activity.
    Biochimica et biophysica acta, 1982, Oct-08, Volume: 718, Issue:2

    Topics: Animals; Carboxy-Lyases; Dithiothreitol; Ditiocarb; Heart; Isoproterenol; Male; Myocardium; Ornithine Decarboxylase; Oxygen; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase

1982
Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:5

    Topics: Aminophylline; Animals; Biotransformation; Dealkylation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Oxidation-Reduction; Theophylline; Xanthine Oxidase

1981
Catecholamine-induced hyperuricemia in eviscerated rats with functional hepatectomy.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:3

    Topics: Animals; Catecholamines; Hepatectomy; Isoproterenol; Liver; Male; Propranolol; Rats; Rats, Inbred Strains; Uric Acid; Xanthine Oxidase

1981
[Effect of allopurinol on adrenergically induced changes in serum lipid levels, heart rate and blood pressure in normal and ischemic rabbits (author's transl)].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:3

    Topics: Allopurinol; Animals; Blood Pressure; Coronary Disease; Fatty Acids, Nonesterified; Female; Heart Rate; Isoproterenol; Lipid Mobilization; Male; Nicotinyl Alcohol; Norepinephrine; Prostaglandins E; Rabbits

1982
Allopurinol amelioration of the pathophysiology of acute myocardial infarction in rats.
    Atherosclerosis, 1981, Volume: 39, Issue:1

    Topics: Allopurinol; Animals; Isoproterenol; Male; Myocardial Infarction; Rats

1981
University of Wisconsin solution preserves myocardial calcium current response to isoproterenol in isolated canine ventricular myocytes.
    Circulation, 1995, Nov-01, Volume: 92, Issue:9 Suppl

    Topics: Adenosine; Allopurinol; Animals; Calcium Channels; Cardioplegic Solutions; Cell Separation; Dogs; Electric Conductivity; Glutathione; Insulin; Isoproterenol; Myocardium; Organ Preservation Solutions; Raffinose; Ventricular Function

1995
Enhancement of endothelium-dependent contraction of the canine coronary artery by UW solution.
    Transplantation, 1994, Dec-27, Volume: 58, Issue:12

    Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Arginine; Cell Communication; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Glutathione; Hypoxia; Insulin; Isoproterenol; Male; Nitric Oxide; omega-N-Methylarginine; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose; Time Factors; Vasoconstriction; Vasodilation

1994
Endothelium-dependent contraction of canine coronary artery is enhanced after 24 hours of preservation with University of Wisconsin solution.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Glutathione; Hypoxia; In Vitro Techniques; Insulin; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose

1995
Morphometry of reversible myocardial damage.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Allopurinol; Animals; Cardiomyopathies; Cytoplasm; Diltiazem; Gerbillinae; Hydroxybutyrates; Isoproterenol; Lipid Metabolism; Male; Myocardium

1994
Inhibition of human neutrophil binding to hydrogen peroxide-treated endothelial cells by cAMP and hydroxyl radical scavengers.
    Free radical biology & medicine, 1996, Volume: 21, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Bucladesine; Cell Adhesion; Cells, Cultured; Cyclic AMP; Deferoxamine; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Isoproterenol; Neutrophils; Pentoxifylline; Tetradecanoylphorbol Acetate; Thrombin; Transferrin; Umbilical Veins; Xanthine Oxidase

1996
Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
    British journal of pharmacology, 1996, Volume: 119, Issue:3

    Topics: Adrenergic beta-Agonists; Allopurinol; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Vasodilator Agents

1996
Role of nitric oxide, cyclic GMP and superoxide in inhibition by adenosine of calcium current in rabbit atrioventricular nodal cells.
    Cardiovascular research, 1997, Volume: 34, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Calcium-Transporting ATPases; Cell Separation; Coloring Agents; Cyclic GMP; Isoproterenol; Methylene Blue; Nitric Oxide; Patch-Clamp Techniques; Rabbits; Superoxides; Xanthine Oxidase

1997
Cultured lung epithelium: A cellular model for lung preservation.
    Cryobiology, 1997, Volume: 35, Issue:3

    Topics: Adenosine; Air; Allopurinol; Bradykinin; Cell Line; Cold Temperature; Electric Impedance; Epithelial Cells; Evaluation Studies as Topic; Glutathione; Histamine; Humans; Insulin; Ion Transport; Isoproterenol; Lung; Lung Transplantation; Models, Biological; Nitrogen; Organ Preservation; Organ Preservation Solutions; Ouabain; Raffinose; Sodium Chloride; Solutions; Tight Junctions

1997
Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats.
    British journal of pharmacology, 1998, Volume: 125, Issue:4

    Topics: Allopurinol; Animals; Atrial Natriuretic Factor; Cyclic GMP; Drug Interactions; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Time Factors; Vasodilation

1998
Isoproterenol inhibits transcription of cardiac cytokine genes induced by reactive oxygen intermediates.
    Anesthesiology, 2002, Volume: 96, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Cytokines; Hypoxanthine; Interleukin-5; Interleukin-6; Isoproterenol; Male; Myocardium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transcription, Genetic; Tumor Necrosis Factor-alpha; Xanthine Oxidase

2002
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
    Circulation research, 2004, Nov-12, Volume: 95, Issue:10

    Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Allopurinol; Animals; Antioxidants; Calcium Signaling; Drug Evaluation, Preclinical; Heart Failure; Isoproterenol; Lipid Peroxidation; Male; Mice; Myocardial Contraction; Myocardial Infarction; Myocardium; Oxidative Stress; Prospective Studies; Random Allocation; Xanthine Oxidase

2004
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
    Journal of translational medicine, 2015, Mar-06, Volume: 13

    Topics: Administration, Oral; Allopurinol; Angiotensin II; Animals; Diet, High-Fat; Electrocardiography; Enzyme Inhibitors; Hemodynamics; Inflammation; Insulin Resistance; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Oxidative Stress; Rats, Wistar; Ultrasonography; Uric Acid; Xanthine Oxidase

2015
Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Alanine Transaminase; Alkaline Phosphatase; Allopurinol; Animals; Aspartate Aminotransferases; Body Weight; Catalase; Creatine Kinase, MB Form; Enzyme Inhibitors; Fibrosis; Glutathione; Heart; Isoproterenol; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Nitric Oxide; Oxidative Stress; Rats; Rats, Long-Evans; Xanthine Oxidase

2015
Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model.
    BMC cardiovascular disorders, 2021, 06-15, Volume: 21, Issue:1

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Female; Fibrosis; Isoproterenol; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; NADPH Oxidases; Nicorandil; Reactive Oxygen Species; Stroke Volume; Superoxide Dismutase; Ventricular Function, Left; Xanthine Oxidase

2021