isoproterenol and acebutolol

isoproterenol has been researched along with acebutolol in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199035 (77.78)18.7374
1990's3 (6.67)18.2507
2000's3 (6.67)29.6817
2010's4 (8.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Pfeifer, S; Zimmer, C1
Ashford, A1
Hamada, Y; Ito, K; Kojima, Y; Kuwabara, S; Sato, I1
Gooren, L; Harms, HH; Hesse, C; Spoelstra, AJ; Verschoor, L1
Allen, KJ; Coghlan, JP; Denton, DA; Graham, WF; Humphery, TJ; Scoggins, BA; Whitworth, JA1
Bravo, EL; Cody, RJ; Tarazi, RC; Wollam, GL1
Haddad, J; Lemaigre, D; Liot, F; Solvignon, F1
Ashford, A; Collins, RF; Gibbons, DO; Lant, AF; Pinder, S1
Basil, B1
Eymery, A; Orehek, J; Orlando, JP1
Collins, RF; Cuthbert, MF1
Mori-Okamoto, J; Namii, Y; Tatsuno, J1
Adrien, J; Dugovic, C; Lanfumey, L1
Boomsma, F; Derkx, FH; Fischberg, DJ; Man in 't Veld, AJ; Molinoff, PB; Schalekamp, MA; van den Meiracker, AH; van Eck, HJ1
Bueno, L; Liberge, M1
Brikas, P; Buéno, L; Fioramonti, J1
Abrahamsson, T1
Palkama, A; Raij, K; Uusitalo, H; Uusitalo, R1
Borchard, U; Hafner, D; Hirth, C1
Paul, V1
Tattersfield, AE; Thomas, MS1
Antonaccio, MJ; DeForrest, JM; High, J; Sybertz, E1
Nakov, R; Ovcharov, R1
Hurwitz, MD; Kallenbach, JM; Pincus, PS1
Corvol, P; Menard, J; Nakane, H; Nakane, Y; Roux, A1
MacLagan, J; Ney, UM1
Homcy, CJ; Wrenn, SM2
Hedges, A; Kilfeather, S; Lima, DR; Turner, P1
Grey, AC; Henderson, AH; Lewis, MJ1
Miyazaki, Y; Nagai, S; Ogawa, K; Ozawa, T; Satake, T; Sugiyama, S1
Abe, N; Kanagawa, T; Kobayashi, A; Nishihara, K; Suzuki, Y1
Kerry, R; Scrutton, MC1
Strubelt, O1
Germond, C; Kallenbach, J; Lewis, M; Muller, F; Steyn, J; Zaltzman, M; Zwi, S1
Hugues, FC; Julien, D; Marche, J; Mougeot, G1
Hellström, PM; Svensson, TH; Thollander, M1
D'Amico, M; Di Filippo, C; Rossi, F1
Bruchatá, K; Čižmáriková, R; Habala, L; Némethy, A; Račanská, E1

Reviews

2 review(s) available for isoproterenol and acebutolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Biotransformation and pharmacokinetics of beta-receptor blockaders].
    Die Pharmazie, 1975, Volume: 30, Issue:10

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Biotransformation; Ethanolamines; Humans; Isoproterenol; Kinetics; Levobunolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Sotalol

1975

Trials

7 trial(s) available for isoproterenol and acebutolol

ArticleYear
[Effects of adrenergic blockade on adipose tissue lipolysis provoked in cats and humans by intravenous perfusion of isoprenaline].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Adipose Tissue; Adrenergic beta-Antagonists; Animals; Cats; Clinical Trials as Topic; Fatty Acids, Nonesterified; Humans; Injections, Intravenous; Isoproterenol; Male; Placebos; Practolol; Propranolol

1975
[Action of acebutolol on heart rate and FEV1 in asthmatic patients. Single intravenous administration and long term oral administration].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Administration, Oral; Adult; Aged; Clinical Trials as Topic; Female; Forced Expiratory Flow Rates; Heart Rate; Humans; Injections, Intravenous; Isoproterenol; Male; Maximal Expiratory Flow Rate; Middle Aged

1975
Comparative effects of acebutolol and practolol on the lipolytic response to isoprenaline.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:1

    Topics: Acebutolol; Adult; Animals; Blood Pressure; Fatty Acids, Nonesterified; Heart Rate; Humans; In Vitro Techniques; Isoproterenol; Lipid Metabolism; Male; Middle Aged; Placebos; Practolol; Propranolol; Rats

1976
Plasma levels and beta-adrenoceptor blockade with acebutolol, practolol and propranolol in man.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:1

    Topics: Acebutolol; Adult; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Practolol; Propranolol

1975
Acute and long-term effects of acebutolol on systemic and renal hemodynamics, body fluid volumes, catecholamines, active renin, aldosterone, and lymphocyte beta-adrenoceptor density.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:4

    Topics: Acebutolol; Body Water; Catecholamines; Drug Administration Schedule; Hemodynamics; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, Adrenergic, beta; Renal Circulation; Renin

1988
Comparison of beta-adrenoceptor selectivity of acebutolol and its metabolite diacetolol with metoprolol and propranolol in normal man.
    European journal of clinical pharmacology, 1986, Volume: 29, Issue:6

    Topics: Acebutolol; Adrenergic beta-Antagonists; Airway Resistance; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Metoprolol; Physical Exertion; Propranolol; Receptors, Adrenergic, beta

1986
Influence of propranolol and acebutolol on isoprenaline-induced changes in heart rate and peripheral blood flow in man.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 251, Issue:1

    Topics: Acebutolol; Adult; Electrocardiography; Heart Rate; Humans; Isoproterenol; Male; Plethysmography; Propranolol; Regional Blood Flow

1981

Other Studies

36 other study(ies) available for isoproterenol and acebutolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Biochemical studies of acebutolol-the beta1 specificity of acebutolol (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:5

    Topics: Acebutolol; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Isoproterenol; Lactates; Liver; Male; Myocardium; Propranolol; Rats

1977
Blockade of isoprenaline-induced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol, metoprolol and acebutolol.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Fatty Acids, Nonesterified; Heart Rate; Humans; Insulin; Isoproterenol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Renin

1978
Haemodynamics of ACTH-induced hypertension in sheep.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Acebutolol; Adrenocorticotropic Hormone; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Female; Heart Rate; Hypertension; Isoproterenol; Sheep; Stroke Volume; Vascular Resistance

1979
Acute hemodynamic effects and cardioselectivity of acebutolol, practolol, and propranolol.
    Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:6

    Topics: Acebutolol; Heart Rate; Hemodynamics; Humans; Isoproterenol; Organ Specificity; Practolol; Propranolol; Time Factors

1979
[Pharmacology of acebutolol in animals].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Animals; Arrhythmias, Cardiac; Blood Pressure; Chemoreceptor Cells; Chloroform; Dogs; Drug Interactions; Heart Rate; Isoproterenol; Ouabain; Practolol; Propranolol; Prostaglandins F; Rabbits

1975
[Study of clinical pharmacology of acebutolol in 5 asthmatic patients].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Aerosols; Asthma; Blood Pressure; Heart Rate; Humans; Isoproterenol; Maximal Expiratory Flow Rate

1975
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate.
    Brain research, 1991, Jan-18, Volume: 539, Issue:1

    Topics: Acebutolol; Albuterol; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Clonidine; Colforsin; Electric Conductivity; Ethanolamines; Glutamates; Glutamic Acid; Isoproterenol; Membrane Potentials; Neurons; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tolazoline; Yohimbine

1991
Beta 1 and beta 2 adrenergic receptors: their role in the regulation of paradoxical sleep in the rat.
    Electroencephalography and clinical neurophysiology, 1985, Volume: 60, Issue:6

    Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clenbuterol; Isoproterenol; Practolol; Prenalterol; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sleep

1985
Comparison of beta 1- and beta 2-adrenoceptor effects on gastric emptying of a fat meal in mice.
    European journal of pharmacology, 1989, May-02, Volume: 164, Issue:1

    Topics: Acebutolol; Animals; Chromium Radioisotopes; Clenbuterol; Dietary Fats; Dobutamine; Gastric Emptying; Isoproterenol; Male; Mice; Propranolol; Receptors, Adrenergic, beta

1989
Central and peripheral beta-adrenergic influences on reticulo-rumen and upper-gut myoelectrical activity in sheep.
    Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:4

    Topics: Acebutolol; Animals; Dobutamine; Duodenum; Electromyography; Female; Gastrointestinal Motility; Intestine, Small; Isoproterenol; Jejunum; Propranolol; Receptors, Adrenergic, beta; Reticulum; Ritodrine; Rumen; Sheep

1989
Characterization of the beta 1-adrenoceptor stimulatory effects of the partial beta 1-agonists acebutolol, xamoterol, H142/08 and H201/70.
    European journal of pharmacology, 1989, May-02, Volume: 164, Issue:1

    Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Propanolamines; Rats; Renin; Uterine Contraction; Xamoterol

1989
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
    Acta ophthalmologica, 1985, Volume: 63, Issue:1

    Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water

1985
In vitro studies on the pharmacological properties of diacetolol, the major metabolite of acebutolol in man.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 273, Issue:1

    Topics: Acebutolol; Action Potentials; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction; Papillary Muscles; Rats; Sympathomimetics; Trachea

1985
Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: 5-Hydroxytryptophan; Acebutolol; Adrenergic beta-Antagonists; Alkaloids; Animals; Butoxamine; Female; Fenclonine; Harmaline; Isoproterenol; Male; Rats; Serotonin; Tremor

1986
Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Blood Pressure; Decerebrate State; Heart; Heart Rate; Hypertension; Isoproterenol; Levobunolol; Male; Metoprolol; Oxprenolol; Propranolol; Rats; Rats, Inbred SHR; Renin; Sympathetic Nervous System; Sympathomimetics; Time Factors

1986
[Effect of adrenergic substances on the capacity of human spermatozoa to penetrate cervical mucus in vitro].
    Eksperimentalna meditsina i morfologiia, 1987, Volume: 26, Issue:1

    Topics: Acebutolol; Cervix Mucus; Dobutamine; Dose-Response Relationship, Drug; Female; Fenoterol; Humans; Isoproterenol; Male; Propranolol; Sperm-Ovum Interactions; Sympathomimetics

1987
Massive propranolol overdose.
    The American journal of medicine, 1986, Volume: 81, Issue:6

    Topics: Acebutolol; Adult; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Labetalol; Suicide, Attempted

1986
Effects of selective and nonselective beta adrenergic agents on renin secretion in isolated perfused rat kidney.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:1

    Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Kidney; Male; Propranolol; Rats; Renin

1980
A comparison of the bronchoconstrictor and beta-adrenoceptor blocking activity of propranolol and acebutolol.
    British journal of pharmacology, 1980, Volume: 68, Issue:2

    Topics: Acebutolol; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Guinea Pigs; Heart Rate; Isoproterenol; Propranolol; Rats

1980
Photoaffinity labeling of the beta-adrenergic receptor: lack of evidence for spare receptors in the reticulocyte.
    Transactions of the Association of American Physicians, 1980, Volume: 93

    Topics: Acebutolol; Adenylyl Cyclases; Adrenergic beta-Antagonists; Affinity Labels; Animals; Azides; Cell Membrane; In Vitro Techniques; Isoproterenol; Kinetics; Photochemistry; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes

1980
Comparison of four different beta-adrenoceptor blocking drugs on lymphocyte isoprenaline-stimulated cyclic AMP production.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:6

    Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Cyclic AMP; Drug Interactions; Female; Humans; Isoproterenol; Lymphocytes; Male; Middle Aged; Pindolol; Timolol

1981
Inotropic beta-blocking potency (pA2) and partial agonist activity of propranolol, practolol, sotalol and acebutolol.
    European journal of pharmacology, 1982, Dec-17, Volume: 86, Issue:1

    Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Papillary Muscles; Practolol; Propranolol; Reserpine; Sotalol

1982
The effects of beta-blocking agents on mitochondrial function in ischemic myocardium.
    Japanese circulation journal, 1984, Volume: 48, Issue:1

    Topics: Acebutolol; Acyl Coenzyme A; Adrenergic beta-Antagonists; Animals; Coronary Disease; Dogs; Female; Isoproterenol; Male; Mitochondria, Heart; Oxygen Consumption; Pindolol; Propranolol; Stereoisomerism

1984
[Effect of acebutolol, an adrenergic beta receptor blocker, on plasma free fatty acids fluctuations caused by isoproterenol administration].
    Kokyu to junkan. Respiration & circulation, 1983, Volume: 31, Issue:11

    Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Dogs; Fatty Acids, Nonesterified; Isoproterenol; Male

1983
Photoaffinity label for the beta-adrenergic receptor: synthesis and effects on isoproterenol-stimulated adenylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:8

    Topics: Acebutolol; Adenylyl Cyclases; Affinity Labels; Amines; Animals; Azides; Enzyme Activation; Isoproterenol; Photochemistry; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes

1980
Binding of [3H]-dihydroalprenolol and [3H]-acetobutolol to human blood platelets is not related to occupancy of beta-adrenoceptors.
    Thrombosis research, 1983, Mar-15, Volume: 29, Issue:6

    Topics: Acebutolol; Alprenolol; Blood Platelets; Butoxamine; Dihydroalprenolol; Humans; Isoproterenol; Kinetics; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta

1983
[Antidotal treatment of acebutolol poisoning].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:10

    Topics: Acebutolol; Animals; Antidotes; Blood Pressure; Dopamine; Epinephrine; Female; Glucagon; Heart Rate; Hemodynamics; Isoproterenol; Male; Metaproterenol; Practolol; Prenalterol; Rabbits; Rats; Rats, Inbred Strains; Respiration; Species Specificity; Time Factors

1984
Survival following massive overdose of adrenergic blocking agents (acebutolol and labetalol).
    European heart journal, 1983, Volume: 4, Issue:5

    Topics: Acebutolol; Adult; Atropine; Blood Pressure; Dopamine; Ethanolamines; Female; Heart Rate; Hemodynamics; Humans; Isoproterenol; Labetalol; Suicide, Attempted; Trimipramine

1983
Beta-adrenoceptors regulate myoelectric activity in the small intestine of rats: stimulation by beta 2 and inhibition by beta 3 subtypes.
    Neurogastroenterology and motility, 1996, Volume: 8, Issue:2

    Topics: Acebutolol; Animals; Intestine, Small; Isoproterenol; Male; Myoelectric Complex, Migrating; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta

1996
Adrenoceptors modulate depressor responses of endothelin-1 into the superior colliculus of rats.
    Life sciences, 1999, Volume: 64, Issue:5

    Topics: Acebutolol; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Albuterol; Animals; Blood Pressure; Clonidine; Dobutamine; Endothelin-1; Isoproterenol; Male; Microinjections; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Superior Colliculi

1999
Synthesis and In Vitro Pharmacological Evaluation of 5-(Alkoxymethyl)-2-(3-alkylamino-2-hydroxypropoxy)phenylethanones Related to Acebutolol and Celiprolol.
    Archiv der Pharmazie, 2016, Volume: 349, Issue:9

    Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Celiprolol; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Isoproterenol; Propanolamines; Structure-Activity Relationship; Trachea

2016