isoproterenol has been researched along with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 22 (62.86) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chiyotani, A; Isono, K; Kondo, M; Konno, K; Sakai, N; Tamaoki, J | 1 |
| Kono, T; Robinson, FW; Shibata, H; Soderling, TR | 1 |
| Furukawa, T; Habuchi, Y; Tanaka, H; Tsujimura, Y | 1 |
| Marumo, F; Nonoguchi, H; Tomita, K | 1 |
| Chang, F; Cohen, IS; DiFrancesco, D; Rosen, MR; Tromba, C | 1 |
| Etgen, AM; Petitti, N | 1 |
| Anwer, K; Hovington, JA; Sanborn, BM | 1 |
| Baldi, G; Bertora, P; Bevilacqua, M; Chebat, E; Norbiato, G; Vago, T | 1 |
| Hui, KK; Yu, JL | 1 |
| Chik, CL; Ho, AK; Klein, DC | 1 |
| Dan'ura, T; Higashi, K; Ishibashi, S; Kurokawa, T; Yamashita, A | 1 |
| Asano, T; Hidaka, H; Ikegaki, I; Satoh, S; Shibuya, M; Suzuki, Y; Takayasu, M | 1 |
| Dan'ura, T; Ishibashi, S; Kurokawa, T; Yamashita, A; Yanagiuchi, H | 1 |
| Hinds, TR; Storm, DR; Wayman, GA | 1 |
| Impey, S; Storm, DR; Wayman, GA | 1 |
| Dehaye, JP; Turner, RJ; Valdez, IH | 1 |
| Doris, R; Houslay, MD; Kilgour, E; Thompson, GE; Vernon, RG | 1 |
| Baldo, GJ; Cohen, IS; Gao, J; Mathias, RT | 1 |
| Cheng, H; Lakatta, EG; Lederer, WJ; Suzuki, T; Xiao, RP | 1 |
| Fenoglio-Preiser, C; Sperelakis, N; Xiong, Z | 1 |
| Satoh, H | 1 |
| Ikeda, SR; Zhu, Y | 1 |
| Benz, D; Möller, K; Perrin, D; Söling, HD | 1 |
| Doris, RA; Houslay, MD; Kilgour, E; Vernon, RG | 1 |
| Cheng, CP; Little, WC; Ohte, N; Suzuki, M; Wang, ZM; Williams, DL | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B | 1 |
| Choi, BH; Earm, YE; Ho, WK; Lee, SH; Yeom, JB; Yoo, S | 1 |
| Anesini, C; Borda, T; Cazaux, CA; Cremaschi, GA; Genaro, AM; Sterin-Borda, L; Wald, M | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| El-Armouche, A; Eschenhagen, T; Jäckel, E; Marx, M; Zolk, O | 1 |
| Frazier, EP; Mathy, MJ; Michel, MC; Peters, SL | 1 |
| Chang, YZ; Chu, L; Guan, P; Li, YQ; Shi, ZH; Wang, FY; Wang, N; Zhang, JP | 1 |
| Du, GH; Fang, LH; Gong, LL; Li, XX; Qin, HL; Sun, JL; Wang, SB | 1 |
| DaSilva, JN; Fernando, P; Moreau, S; Valdivia, A | 1 |
| Ma, K; Zhou, FT | 1 |
35 other study(ies) available for isoproterenol and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
| Article | Year |
|---|---|
Thromboxane A2 mimetic U46619 stimulates ciliary motility of rabbit tracheal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cilia; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fatty Acids, Unsaturated; Hydrazines; Isoproterenol; Isoquinolines; Male; Movement; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Thromboxane A2; Trachea; Verapamil | 1992 |
Effects of okadaic acid on insulin-sensitive cAMP phosphodiesterase in rat adipocytes. Evidence that insulin may stimulate the enzyme by phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Biological Transport; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Glucose; Insulin; Isoproterenol; Isoquinolines; Lipolysis; Okadaic Acid; Phosphorylation; Piperazines; Rats; Rats, Inbred Strains | 1991 |
Caffeine-induced block of Na+ current in guinea pig single ventricular cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caffeine; Calcium; Electric Conductivity; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Isoquinolines; Kinetics; Membrane Potentials; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sarcoplasmic Reticulum; Signal Transduction; Sodium; Sodium Channels; Ventricular Function | 1991 |
Effects of endothelin on peptide-dependent cyclic adenosine monophosphate accumulation along the nephron segments of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Calcitonin; Calcium; Cyclic AMP; Endothelins; Glucagon; In Vitro Techniques; Indomethacin; Isoproterenol; Isoquinolines; Kidney Tubules; Loop of Henle; Nicardipine; Parathyroid Hormone; Peptides; Piperazines; Protein Kinase C; Rats | 1990 |
Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Animals; Colforsin; Dogs; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Purkinje Fibers | 1991 |
Protein kinase C and phospholipase C mediate alpha 1- and beta-adrenoceptor intercommunication in rat hypothalamic slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cyclic AMP; Enzyme Activation; Estradiol; Female; Hypothalamus; Isoproterenol; Isoquinolines; Ovariectomy; Phenylephrine; Phospholipases A; Phospholipases A2; Piperazines; Preoptic Area; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Staurosporine; Type C Phospholipases | 1991 |
Involvement of protein kinase A in the regulation of intracellular free calcium and phosphoinositide turnover in rat myometrium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cyclic AMP; Female; Inositol Phosphates; Isoproterenol; Isoquinolines; Myometrium; Phosphatidylinositols; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Relaxin; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Respiratory-burst stimulants desensitize beta-2 adrenoceptors on human polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Antagonists; Binding, Competitive; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Isoproterenol; Isoquinolines; Kinetics; Neutrophils; Piperazines; Propanolamines; Protein Kinase C; Receptors, Adrenergic, beta; Superoxides | 1990 |
Effects of protein kinase inhibitor, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, on beta-2 adrenergic receptor activation and desensitization in intact human lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adult; Cyclic AMP; Drug Synergism; Humans; Iodocyanopindolol; Isoproterenol; Isoquinolines; Lymphocytes; Pindolol; Piperazines; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1989 |
Effects of protein kinase inhibitor (1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H7) on protein kinase C activity and adrenergic stimulation of cAMP and cGMP in rat pinealocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Isoproterenol; Isoquinolines; Norepinephrine; Pineal Gland; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1988 |
Induction of desensitization by phorbol ester to beta-adrenergic agonist stimulation in adenylate cyclase system of rat reticulocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Diglycerides; Guanylyl Imidodiphosphate; Isoproterenol; Isoquinolines; Male; Phorbols; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Reticulocytes; Tetradecanoylphorbol Acetate | 1986 |
Mechanism of action of a novel antivasospasm drug, HA1077.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium Chloride; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intra-Arterial; Injections, Intraventricular; Ischemic Attack, Transient; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Nicardipine; Rabbits; Vasodilation | 1987 |
Characterization of heterologous desensitization of rat reticulocyte adenylate cyclase system.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Isoproterenol; Isoquinolines; Piperazines; Protein Kinases; Rats; Reticulocytes; Sodium Fluoride; Time Factors | 1987 |
Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Isoquinolines; Kidney; Kinetics; Models, Biological; Oscillometry; Phosphatidylinositols; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucagon; Signal Transduction; Time Factors | 1995 |
Ca2+ inhibition of type III adenylyl cyclase in vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Line; Cell Membrane; Embryo, Mammalian; Gene Library; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoenzymes; Isoproterenol; Isoquinolines; Kidney; Kinetics; Piperazines; Receptors, Glucagon; Recombinant Proteins; Transfection | 1995 |
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland | 1993 |
Modulation of adenosine signalling in sheep adipose tissue by growth hormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adipose Tissue; Animals; Cattle; Cells, Cultured; Ethers, Cyclic; Growth Hormone; Isoproterenol; Isoquinolines; Kinetics; Lipolysis; Okadaic Acid; Phenylisopropyladenosine; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Recombinant Proteins; Sheep; Signal Transduction | 1995 |
Regulation of the beta-stimulation of the Na(+)-K+ pump current in guinea-pig ventricular myocytes by a cAMP-dependent PKA pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Guinea Pigs; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Marine Toxins; Myocardium; Oxazoles; Phosphoprotein Phosphatases; Piperazines; Protein Kinase Inhibitors; Sodium-Potassium-Exchanging ATPase | 1994 |
Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Imidodiphosphate; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Egtazic Acid; Electric Conductivity; Electric Stimulation; Heart; Isoenzymes; Isoproterenol; Isoquinolines; Kinetics; Membrane Potentials; Myocardium; Norepinephrine; Piperazines; Protein Kinase Inhibitors; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Thioridazine; Time Factors | 1994 |
Isoproterenol modulates the calcium channels through two different mechanisms in smooth-muscle cells from rabbit portal vein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Triphosphate; Ion Channel Gating; Isoproterenol; Isoquinolines; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Piperazines; Portal Vein; Protein Kinase Inhibitors; Rabbits; Signal Transduction | 1994 |
Elevation of intracellular Ca2+ concentration by protein kinase C stimulation in isolated single rabbit sino-atrial node cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Fura-2; In Vitro Techniques; Isoproterenol; Isoquinolines; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rabbits; Sinoatrial Node; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
2,3-butanedione monoxime blockade of Ca2+ currents in adult rat sympathetic neurons does not involve 'chemical phosphatase' activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Diacetyl; Electrophysiology; Ganglia, Sympathetic; Isoproterenol; Isoquinolines; Male; Neurons; Phosphoric Monoester Hydrolases; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Wistar; Thionucleotides | 1993 |
The role of protein kinase C in carbachol-induced and of cAMP-dependent protein kinase in isoproterenol-induced secretion in primary cultured guinea pig parotid acinar cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amylases; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Exocytosis; Guinea Pigs; Immunoblotting; Isoproterenol; Isoquinolines; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Piperazines; Protein Binding; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1996 |
Regulation of the GTP-binding protein-based antilipolytic system of sheep adipocytes by growth hormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cell Membrane; Colforsin; Culture Techniques; Enzyme Inhibitors; Growth Hormone; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isomerism; Isoproterenol; Lipolysis; Male; Models, Biological; Okadaic Acid; Pertussis Toxin; Phenylisopropyladenosine; Protein Binding; Receptors, Purinergic P1; Sheep; Stimulation, Chemical; Virulence Factors, Bordetella | 1998 |
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Cell Size; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium-Hydrogen Exchangers; Staurosporine | 1998 |
Regulation of the L-type Ca2+ channel current in rat pinealocytes: role of basal phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Agonists; Alkaloids; Animals; Antifungal Agents; Calcium Channels; Calcium Channels, L-Type; Carbazoles; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Indoles; Isoproterenol; Isoquinolines; Male; Marine Toxins; Membrane Potentials; Nerve Tissue Proteins; Norepinephrine; Okadaic Acid; Oxazoles; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Phosphorylation; Pineal Gland; Protein Kinase C; Pyrans; Rats; Rats, Sprague-Dawley; Spiro Compounds; Sulfonamides; Sympathomimetics | 1999 |
Dual effect of nitric oxide on the hyperpolarization-activated inward current (I(f)) in sino-atrial node cells of the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Acetylcholine; Adrenergic beta-Agonists; Animals; Electrophysiology; Enzyme Inhibitors; Female; Guanosine Monophosphate; Isoproterenol; Male; Methylene Blue; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Rabbits; Sinoatrial Node; Time Factors; Vasodilator Agents | 1998 |
Altered beta-adrenoceptor function associated to protein kinase C activation in hyperproliferative T lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Adrenergic beta-Agonists; Cell Division; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoproterenol; Lymphoma, T-Cell; Maleimides; Neuroimmunomodulation; Protein Kinase C; Receptors, Adrenergic, beta; Signal Transduction; T-Lymphocytes; Tumor Cells, Cultured | 2000 |
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Calcium; Calmodulin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Feedback; Female; Glutamic Acid; Imidazoles; Imines; Isoenzymes; Isoproterenol; Isoquinolines; Kainic Acid; Male; Mice; N-Methylaspartate; Nerve Tissue Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Presynaptic; Second Messenger Systems; Sulfonamides; Synaptic Transmission; Trifluoperazine | 2003 |
Beta-adrenergic stimulation induces cardiac ankyrin repeat protein expression: involvement of protein kinase A and calmodulin-dependent kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Agonists; Animals; Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Isoproterenol; Male; Muscle Proteins; Myocardial Contraction; Myocardium; Nuclear Proteins; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Repressor Proteins; RNA, Messenger; Thionucleotides | 2003 |
Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Potassium Channels; Potassium Chloride; Rats; Signal Transduction; Urinary Bladder | 2005 |
Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; CASP8 and FADD-Like Apoptosis Regulating Protein; Enzyme Activation; Gene Expression; Heart; Heart Failure; Hemodynamics; Isoproterenol; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2011 |
Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Berberine; Cardiotonic Agents; Isoproterenol; Male; Mitochondria, Heart; Myocardial Infarction; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein | 2012 |
N-[(11)C]-methyl-hydroxyfasudil is a potential biomarker of cardiac hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biomarkers; Cardiomegaly; Cell Nucleus; Cell Nucleus Size; Enzyme Activation; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; TOR Serine-Threonine Kinases | 2015 |
Fasudil protects against isoproterenol-induced myocardial infarction in mice via inhibiting Rho/ROCK signaling pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Injections, Subcutaneous; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardial Infarction; Oxidative Stress; Protective Agents; Protein Kinase Inhibitors; rho-Associated Kinases; rhoC GTP-Binding Protein; Signal Transduction | 2020 |