isophosphamide mustard has been researched along with ifosfamide in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Czownicki, Z; Misiura, K; Okruszek, A; Pankiewicz, K; Stec, WJ; Utracka, B | 1 |
| Ciesielska, E; Kinas, R; Studzian, K; Szmigiero, L | 1 |
| Houghton, PJ; Masurel, D; Wainer, IW; Young, CL | 1 |
| Idle, JR; Lind, MJ; Roberts, HL; Thatcher, N | 1 |
| Boal, JH; Boyd, VL; Egan, W; Ludeman, SM; Williamson, M | 1 |
| Colvin, M; Kesarwala, HH; Kim, HC; Saidi, P | 1 |
| Bryant, BM; Ford, HT; Jarman, M; Smith, IE | 1 |
| Holdiness, MR; Morgan, LR | 1 |
| Corbett, TH; Dykes, DJ; Struck, RF; Suling, WJ; Trader, MW | 1 |
| Baker, MH; Bryant, BM; Jarman, M; Smith, IE; Smyth, JF | 1 |
| Colvin, ME; Colvin, OM; Gamcsik, MP; Ludeman, SM; Millis, KK; Shulman-Roskes, EM | 1 |
| Bertram, B; Hilgard, P; Nowrousian, MR; Pohl, J; Stüben, J; Wiessler, M | 1 |
| Hansen, L; Harland, SJ; Hartley, JM; Nicholson, PW; Pasini, F; Souhami, RL | 1 |
| Waxman, DJ; Weber, GF | 1 |
| Chan, KK; Muggia, F; Zheng, JJ | 1 |
| Ciesielska, E; Dzwonkowska, A; Kinas, R; Mordalska, A; Szmigiero, L | 1 |
| Chan, KK; Wang, JJ | 1 |
| Beijnen, JH; Bult, A; Kaijser, GP; Rozendom, E; Underberg, WJ | 1 |
| Brennan, C; Hartley, JM; Nicholson, PW; Singer, JM; Souhami, RL | 1 |
| Blaschke, G; Boos, J; Hohenlöchter, B; Jürgens, H; Rossi, R; Silies, H | 1 |
| Berardini, MD; Davis, RL; Loechler, EL; Struck, RF | 1 |
| Kuśnierczyk, H; Misiura, K; Opolski, A; Szymanowicz, D; Wietrzyk, J | 1 |
| Gamcsik, MP; Ludeman, SM | 1 |
| Chen, XY; Sun, YM; Zhong, DF | 1 |
| Beck-Schimmer, B; Biber, J; Hernando, N; Murer, H; Patzer, L; Ziegler, U | 1 |
| Chen, N; Hanly, L; Koren, G; Rieder, M; Yeger, H | 1 |
| Amedio, J; Jones, B; Komarnitsky, P; Miller, GT; Wallner, BP | 1 |
| Mazur, L; Opydo-Chanek, M; Stojak, M | 1 |
| Bertrand, JR; Caron, J; Chapuis, H; Couvreur, P; Daville, A; Deroussent, A; Desmaele, D; Le Cam, E; Lesueur, LL; Martens, T; Paci, A; Pioche Durieu, C; Rivard, M; Skarbek, C; Vassal, G | 1 |
| Jiang, L; Li, Z; Qin, J; Shi, Y; Su, W; Tao, T; Xu, C; Zhu, Y | 1 |
1 review(s) available for isophosphamide mustard and ifosfamide
| Article | Year |
|---|---|
Mechanisms of resistance against cyclophosphamide and ifosfamide: can they be overcome without sacrificing selectivity?
Topics: Acrolein; Aldehyde Dehydrogenase; Antineoplastic Agents, Alkylating; Cyclophosphamide; DNA Repair; Drug Resistance, Neoplasm; Humans; Ifosfamide; Models, Chemical; O(6)-Methylguanine-DNA Methyltransferase; Phosphoramide Mustards; Stereoisomerism | 2002 |
2 trial(s) available for isophosphamide mustard and ifosfamide
| Article | Year |
|---|---|
Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) in patients with advanced carcinoma.
Topics: Acrolein; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Female; Hematuria; Humans; Ifosfamide; Kinetics; Lung Neoplasms; Male; Mercaptoethanol; Mesna; Phosphoramide Mustards; Urinary Bladder | 1980 |
The pharmacokinetics and metabolism of ifosfamide during bolus and infusional administration: a randomized cross-over study.
Topics: Adult; Aged; Antineoplastic Agents; Biotransformation; Cross-Over Studies; Cyclophosphamide; Dexamethasone; Female; Humans; Ifosfamide; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Phosphoramide Mustards; Sarcoma; Sarcoma, Ewing | 1998 |
27 other study(ies) available for isophosphamide mustard and ifosfamide
| Article | Year |
|---|---|
Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine.
Topics: Cyclophosphamide; Humans; Ifosfamide; Magnetic Resonance Spectroscopy; Methods; Stereoisomerism | 1983 |
Effects of alkylating metabolites of ifosfamide and its bromo analogues on DNA of HeLa cells.
Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA, Neoplasm; Dose-Response Relationship, Drug; HeLa Cells; Humans; Ifosfamide; Phosphoramide Mustards | 1992 |
Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice.
Topics: Animals; Female; Humans; Ifosfamide; In Vitro Techniques; Mice; Mice, Inbred CBA; Microsomes, Liver; Neoplasm Transplantation; Phosphoramide Mustards; Rhabdomyosarcoma; Stereoisomerism; Transplantation, Heterologous | 1990 |
The effect of route of administration and fractionation of dose on the metabolism of ifosfamide.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chromatography, Thin Layer; Cyclophosphamide; Densitometry; Drug Administration Schedule; Humans; Ifosfamide; Infusions, Intravenous; Middle Aged; Phosphoramide Mustards | 1990 |
31P NMR studies of the kinetics of bisalkylation by isophosphoramide mustard: comparisons with phosphoramide mustard.
Topics: Alkylating Agents; Antineoplastic Agents; Chemical Phenomena; Chemistry; Half-Life; Ifosfamide; Kinetics; Magnetic Resonance Spectroscopy; Phosphoramide Mustards; Phosphorus Radioisotopes | 1989 |
Hypersensitivity reaction to a metabolite of cyclophosphamide.
Topics: Cyclophosphamide; Drug Hypersensitivity; Histamine; Humans; Ifosfamide; Intradermal Tests; Male; Middle Aged; Multiple Myeloma; Phosphoramide Mustards | 1985 |
Electron-capture--gas chromatographic analysis of ifosfamide in human plasma and urine.
Topics: Cyclophosphamide; Fluorocarbons; Humans; Ifosfamide; Lung Neoplasms; Phosphoramide Mustards | 1983 |
Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Cyclophosphamide; Female; Ifosfamide; Leukemia, Experimental; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Phosphoramide Mustards; Rats; Sarcoma, Yoshida | 1983 |
Quantification by gas chromatography of N,N'-di-(2-chloroethyl)-phosphorodiamidic acid in the plasma of patients receiving isophosphamide.
Topics: Chromatography, Gas; Cyclophosphamide; Humans; Ifosfamide; Phosphoramide Mustards | 1980 |
Comparison of the protonation of isophosphoramide mustard and phosphoramide mustard.
Topics: Antineoplastic Agents; Ifosfamide; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphoramide Mustards; Protons; Thermodynamics | 1995 |
D-19575--a sugar-linked isophosphoramide mustard derivative exploiting transmembrane glucose transport.
Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Disease Models, Animal; Drug Evaluation; Drug Tolerance; Female; Glucose; Ifosfamide; Kidney; Leukocytes; Mice; Monosaccharide Transport Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phlorhizin; Phosphoramide Mustards; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Spleen; Tumor Cells, Cultured | 1995 |
Metabolism of ifosfamide during a 3 day infusion.
Topics: Adenocarcinoma; Chromatography, Thin Layer; Female; Humans; Ifosfamide; Male; Neuroectodermal Tumors, Primitive; Osteosarcoma; Phosphoramide Mustards; Rhabdomyosarcoma; Sarcoma, Ewing; Time Factors | 1994 |
Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carmustine; Coenzymes; Cyclophosphamide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Ifosfamide; Liver; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Phosphoramide Mustards; Proadifen; Rats | 1993 |
Preclinical pharmacokinetics and stability of isophosphoramide mustard.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Drug Stability; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Ifosfamide; Male; Phosphoramide Mustards; Protein Binding; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1994 |
Sister chromatid exchanges induced in vitro in human lymphocytes by N-substituted phosphorodiamidic acids.
Topics: Antineoplastic Agents; Humans; Ifosfamide; Lymphocytes; Phosphoramide Mustards; Sister Chromatid Exchange | 1993 |
Analysis of ifosfamide, 4-hydroxyifosfamide, N2-dechloroethylifosfamide, N3-dechloroethylifosfamide and iphosphoramide mustard in plasma by gas chromatography-mass spectrometry.
Topics: Animals; Antineoplastic Agents, Alkylating; Deuterium; Gas Chromatography-Mass Spectrometry; Ifosfamide; Kinetics; Male; Phosphoramide Mustards; Rats; Rats, Sprague-Dawley | 1995 |
Analysis of ifosforamide mustard, the active metabolite of ifosfamide, in plasma.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Ifosfamide; Phosphoramide Mustards; Reproducibility of Results; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet | 1996 |
Excretion kinetics of ifosfamide side-chain metabolites in children on continuous and short-term infusion.
Topics: Acetaldehyde; Acrolein; Adolescent; Adult; Antineoplastic Agents, Alkylating; Child; Female; Humans; Ifosfamide; Infusions, Intravenous; Kidney; Male; Neoplasms; Phosphoramide Mustards | 1998 |
DNA guanine-guanine crosslinking sequence specificity of isophosphoramide mustard, the alkylating metabolite of the clinical antitumor agent ifosfamide.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Cross-Linking Reagents; DNA; Guanine; Humans; Ifosfamide; Phosphoramide Mustards | 2000 |
Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).
Topics: Animals; Antineoplastic Agents; Carcinoma; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Drug Stability; Esterases; Esters; Humans; Ifosfamide; Leukemia; Mice; Mouth Neoplasms; Nucleotides; Phosphoramide Mustards; Prodrugs; Tumor Cells, Cultured | 2002 |
[Identification of glufosfamide metabolites in rats].
Topics: Animals; Antineoplastic Agents, Alkylating; Gas Chromatography-Mass Spectrometry; Glucose; Ifosfamide; Injections, Intravenous; Male; Phosphoramide Mustards; Rats; Rats, Wistar | 2006 |
Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.
Topics: Acetaldehyde; Animals; Antineoplastic Agents, Alkylating; Biological Transport; Cell Death; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Ifosfamide; Kidney; Mesna; Opossums; Phosphates; Phosphoramide Mustards; RNA, Messenger; Sodium-Phosphate Cotransporter Proteins, Type IIa | 2006 |
The effect of N-acetylcysteine on the antitumor activity of ifosfamide.
Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Ifosfamide; Mesna; Neuroblastoma; Phosphoramide Mustards; Rhabdomyosarcoma | 2011 |
Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Disease-Free Survival; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Ifosfamide; Injections, Intravenous; Leukemia, Experimental; Lysine; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Phosphoramide Mustards; Rats; Rats, Sprague-Dawley; Taxoids; Xenograft Model Antitumor Assays | 2012 |
In vitro cytotoxicity testing of new generation oxazaphosphorines against human histiocytic lymphoma cells.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Proliferation; Cyclophosphamide; Flow Cytometry; Glucose; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Membrane Potential, Mitochondrial; Necrosis; Phosphoramide Mustards; Tumor Cells, Cultured | 2013 |
Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.
Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Drug Design; Humans; Ifosfamide; Phosphoramide Mustards; Prodrugs | 2015 |
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice.
Topics: Acrolein; Animals; Antineoplastic Agents, Alkylating; Calcium Channel Blockers; Cell Survival; Coculture Techniques; Epithelial Cells; Hep G2 Cells; Humans; Ifosfamide; Kidney; Lab-On-A-Chip Devices; Liver; Phosphoramide Mustards; Rats; Verapamil | 2018 |