isopentenyl pyrophosphate and pyrophosphate

isopentenyl pyrophosphate has been researched along with pyrophosphate in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19907 (20.00)18.7374
1990's3 (8.57)18.2507
2000's13 (37.14)29.6817
2010's10 (28.57)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Kawahara, Y; Momose, K; Shimizu, S; Sugawara, H; Yamamoto, T1
Koyama, T; Ogura, K; Yoshida, I2
Davisson, VJ; Poulter, CD; Woodside, AB1
Bloom, BR; Brenner, MB; Morita, CT; Nieves, E; Tanaka, Y1
Colizzi, V; Dieli, F; Malkovsky, M; Poccia, F; Pollak, A; Salerno, A; Sireci, G1
Bacher, A; Eisenreich, W; Rohdich, F1
Lee, HK; Li, H; Mariuzza, RA; Morita, CT; Tanaka, Y; Wang, H1
Espinosa, E; Fournié, JJ; Hudrisier, D; Tabiasco, J1
Jiang, JL; Lu, M; Wang, YD; Wu, JC; Yuan, YJ1
Bukowski, JF; Chen, ZW; Lee, HK; Li, H; Mariuzza, RA; Morita, CT; Nam, KH; Wang, H1
Boronat, A; Frapart, Y; Garcia Estrabot, A; Marquet, A; Rodríguez-Concepción, M; Rohmer, M; Seemann, M; Tritsch, D; Tse Sum Bui, B; Wolff, M1
ARREGUIN, B; HENNING, U; LYNEN, F; MOESLEIN, EM1
BLOCH, K; CHAYKIN, S; DE WAARD, A; PHILLIPS, AH1
RILLING, HC; SALOKANGAS, RA; SAMUELS, LT1
BLOCH, K; DEWAARD, A; LINDBERG, M; YUAN, C1
Eubanks, LM; Poulter, CD; Scholte, AA; Vederas, JC1
Casetti, R; Colizzi, V; D'Offizi, G; Dieli, F; Malkovsky, M; Mattei, M; Perretta, G; Poccia, F; Taglioni, A1
Noghabi, KA; Shin, YC; Zahiri, HS1
Giner, JL; Jin, C; Kuzuyama, T; Lee, HK; Märker-Hermann, E; Morita, CT; Nieves, E; Pasa-Tolic, L; Puan, KJ; Raker, AM; Samuelson, MI; Sarikonda, G; Wang, H1
Liang, PH; Liu, HG; Lu, YP1
de Diego, A; Pérez-Zúñiga, FJ; Sillero, A; Sillero, MA; Silva, JA; Tavares, JE1
Charbonneau, AL; Larson, M; Last, RL; Pichersky, E; Schauvinhold, I; Schilmiller, AL; Schmidt, A; Wilkerson, C; Xu, R1
Boudjema, K; Bouet-Toussaint, F; Cabillic, F; Catros, V; Daniel, P; de La Pintière, CT; Lavoué, V; Mönkkönen, H; Mönkkönen, J; Rioux-Leclerc, N; Toutirais, O; Turlin, B1
Doherty, DG; Dunne, MR; Madrigal-Estebas, L; Mangan, BA1
Bein, G; Hackstein, H; Jomaa, H; Kubin, T; Sandvold, H; Soriano-Sarabia, N1
Berghuis, AM; De Schutter, JW; Lin, YS; Park, J; Tsantrizos, YS1
Chen, HC; Davey, MS; Eberl, M; James, LC; Keeble, AH; Price, AJ; Rhodes, DA; Trowsdale, J1
Bouwmeester, H; Dong, L; Jongedijk, E; Van Der Krol, A1
Jiang, L; Li, W; Luo, Y; Yang, L; Yang, Y; Zhang, G1
Agosin, E; Almonacid, D; González-Nilo, F; Rubat, S; Sepúlveda, R; Varas, I1
Davey, MS; Hunter, S; Oo, YH; Willcox, BE; Willcox, CR1
Bessman, MJ1
Amzel, LM; Aripirala, S; Gabelli, SB; Kim, YS; Maheshwari, S; Murphy, M1
Cao, X; Tang, F; Wang, J; Zhang, Y1

Reviews

2 review(s) available for isopentenyl pyrophosphate and pyrophosphate

ArticleYear
Deoxyxylulose phosphate pathway to terpenoids.
    Trends in plant science, 2001, Volume: 6, Issue:2

    Topics: Diphosphates; Enzymes; Genes, Bacterial; Genes, Plant; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Terpenes; Xylulose

2001
Vδ2
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adaptive Immunity; Antigens, Bacterial; Diphosphates; Hemiterpenes; Humans; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets

2018

Other Studies

33 other study(ies) available for isopentenyl pyrophosphate and pyrophosphate

ArticleYear
Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart.
    Archives of biochemistry and biophysics, 1991, Volume: 284, Issue:1

    Topics: Animals; Diphosphates; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Iodoacetamide; Isoproterenol; Mevalonic Acid; Mitochondria, Heart; Myocardium; Organophosphorus Compounds; Polyisoprenyl Phosphates; Rats; Rats, Inbred Strains; Terpenes; Ubiquinone

1991
Protection of hexaprenyl-diphosphate synthase of Micrococcus luteus B-P 26 against inactivation by sulphydryl reagents and arginine-specific reagents.
    Biochimica et biophysica acta, 1989, Apr-06, Volume: 995, Issue:2

    Topics: Aldehydes; Alkyl and Aryl Transferases; Arginine; Butanones; Chloromercuribenzoates; Cyclohexanes; Cyclohexanones; Diacetyl; Dimethylallyltranstransferase; Diphosphates; Enzyme Activation; Ethylmaleimide; Hemiterpenes; Iodoacetamide; Magnesium; Micrococcus; Organophosphorus Compounds; p-Chloromercuribenzoic Acid; Phenylglyoxal; Polyisoprenyl Phosphates; Sesquiterpenes; Sulfhydryl Reagents; Transferases

1989
Formation of a stable and catalytically active complex of the two essential components of hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26.
    Biochemical and biophysical research communications, 1989, Apr-28, Volume: 160, Issue:2

    Topics: Alkyl and Aryl Transferases; Catalysis; Chromatography, Gel; Dimethylallyltranstransferase; Diphosphates; Enzyme Stability; Hemiterpenes; Macromolecular Substances; Micrococcus; Organophosphorus Compounds; Polyisoprenyl Phosphates; Sesquiterpenes; Substrate Specificity; Transferases

1989
Synthesis of allylic and homoallylic isoprenoid pyrophosphates.
    Methods in enzymology, 1985, Volume: 110

    Topics: Diphosphates; Hemiterpenes; Organophosphorus Compounds; Polyisoprenyl Phosphates; Sesquiterpenes

1985
Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.
    Nature, 1995, May-11, Volume: 375, Issue:6527

    Topics: Antigens, Bacterial; Cell Line; Clone Cells; Diphosphates; Hemiterpenes; Humans; Mycobacterium; Mycobacterium tuberculosis; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes

1995
In vivo gammadelta T cell priming to mycobacterial antigens by primary Mycobacterium tuberculosis infection and exposure to nonpeptidic ligands.
    Molecular medicine (Cambridge, Mass.), 1999, Volume: 5, Issue:7

    Topics: Animals; Antigens; Antigens, Bacterial; Case-Control Studies; Child; Child, Preschool; Diphosphates; Female; Hemiterpenes; Humans; Infant; Interferon-gamma; Ligands; Macaca mulatta; Male; Mycobacterium tuberculosis; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; Sugar Phosphates; T-Lymphocytes; Tuberculosis; Tumor Necrosis Factor-alpha

1999
Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human gamma delta T cells.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jul-01, Volume: 167, Issue:1

    Topics: Adult; Antigens; Binding Sites; Cell Line; Clone Cells; Diphosphates; Epitopes, T-Lymphocyte; Hemiterpenes; Humans; Jurkat Cells; Organophosphorus Compounds; Polyisoprenyl Phosphates; Receptors, Antigen, T-Cell, gamma-delta; Sesquiterpenes; T-Lymphocyte Subsets; Transfection

2001
Synaptic transfer by human gamma delta T cells stimulated with soluble or cellular antigens.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Jun-15, Volume: 168, Issue:12

    Topics: Antigens; Burkitt Lymphoma; Cell Communication; Cell Membrane; Diphosphates; Hemiterpenes; Humans; K562 Cells; Levamisole; Lymphocyte Activation; Lymphoma, Non-Hodgkin; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; Solubility; T-Lymphocyte Subsets; Tumor Cells, Cultured

2002
Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei.
    Biotechnology and applied biochemistry, 2003, Volume: 37, Issue:Pt 1

    Topics: Bridged-Ring Compounds; Cells, Cultured; Chlormequat; Culture Media; Diphosphates; Enzyme Inhibitors; Glyceraldehyde; Hemiterpenes; Lovastatin; Organophosphorus Compounds; Species Specificity; Taxoids; Taxus

2003
Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Apr-01, Volume: 170, Issue:7

    Topics: Amino Acid Sequence; Animals; Antigen Presentation; Antigens, Bacterial; Butylamines; Clone Cells; Conserved Sequence; Diphosphates; Epitopes, T-Lymphocyte; Fetal Blood; Hemiterpenes; Humans; Infant, Newborn; Lymphocyte Activation; Macaca mulatta; Molecular Sequence Data; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Superantigens; T-Lymphocyte Subsets; Transfection; Tumor Cells, Cultured

2003
Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein.
    FEBS letters, 2003, Apr-24, Volume: 541, Issue:1-3

    Topics: Diphosphates; Electron Spin Resonance Spectroscopy; Erythritol; Escherichia coli; Escherichia coli Proteins; Hemiterpenes; Iron-Sulfur Proteins; Models, Chemical; NADH, NADPH Oxidoreductases; Organophosphorus Compounds; Oxidoreductases; Polyisoprenyl Phosphate Sugars; Sugar Phosphates

2003
[On the formation of rubber from isopentenyl pyrophosphates. On the biosynthesis of terpenes. XI].
    Biochemische Zeitschrift, 1961, Volume: 333

    Topics: Diphosphates; Hemiterpenes; Organophosphorus Compounds; Rubber; Terpenes

1961
Mevalonic acid pyrophosphate and isopentenylpyrophosphate.
    The Journal of biological chemistry, 1959, Volume: 234

    Topics: Diphosphates; Fatty Acids; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds

1959
TERPENE METABOLISM IN THE RAT TESTIS. I. THE CONVERSION OF ISOPENTENYL PYROPHOSPHATE TO SQUALENE AND STEROLS.
    Biochemistry, 1964, Volume: 3

    Topics: Carbon Isotopes; Cholesterol; Chromatography; Diphosphates; Fishes; Hemiterpenes; Humans; Lipid Metabolism; Male; Metabolism; Mevalonic Acid; NADP; Organophosphorus Compounds; Rats; Research; Saccharomyces; Squalene; Sterols; Terpenes; Testis

1964
On the mechanism of formation of isopentenylpyrophosphate.
    Biochemistry, 1962, Volume: 1

    Topics: Diphosphates; Hemiterpenes; Organophosphorus Compounds

1962
Synthesis and biological activity of isopentenyl diphosphate analogues.
    Bioorganic & medicinal chemistry, 2004, Feb-15, Volume: 12, Issue:4

    Topics: Alkyl and Aryl Transferases; Diphosphates; Farnesyltranstransferase; Hemiterpenes; Inhibitory Concentration 50; Maleates; Molecular Structure; Organophosphorus Compounds

2004
Drug-induced expansion and differentiation of V gamma 9V delta 2 T cells in vivo: the role of exogenous IL-2.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Aug-01, Volume: 175, Issue:3

    Topics: 2,3-Diphosphoglycerate; Animals; Antigens; CD4-CD8 Ratio; Cell Differentiation; Cell Proliferation; Cells, Cultured; Diphosphates; Diphosphonates; Epoxy Compounds; Hemiterpenes; Immunologic Memory; Injections, Intravenous; Injections, Subcutaneous; Interferon-gamma; Interleukin-2; Macaca fascicularis; Organophosphorus Compounds; Pamidronate; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Th1 Cells

2005
Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production.
    Applied microbiology and biotechnology, 2006, Volume: 73, Issue:4

    Topics: Agrobacterium tumefaciens; Alkyl and Aryl Transferases; Chromatography, Thin Layer; Cloning, Molecular; Coenzymes; Diphosphates; Diterpenes; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hemiterpenes; Kinetics; Molecular Sequence Data; Organophosphorus Compounds; Polyisoprenyl Phosphates; Rhodobacter sphaeroides; Sequence Analysis, DNA; Sesquiterpenes; Substrate Specificity; Ubiquinone

2006
Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells.
    International immunology, 2007, Volume: 19, Issue:5

    Topics: Animals; Diphosphates; Hemiterpenes; Humans; Lymphocyte Activation; Mice; Models, Animal; Molecular Structure; Mycobacterium smegmatis; Organophosphorus Compounds; Polyisoprenyl Phosphates; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets

2007
Different reaction mechanisms for cis- and trans-prenyltransferases.
    Biochemical and biophysical research communications, 2009, Feb-06, Volume: 379, Issue:2

    Topics: Alkyl and Aryl Transferases; Chromatography, Thin Layer; Diphosphates; Hemiterpenes; Organophosphates; Organophosphorus Compounds; Polyisoprenyl Phosphates; Sesquiterpenes; Substrate Specificity; Transferases

2009
Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases
    Biochemical pharmacology, 2009, Aug-15, Volume: 78, Issue:4

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Chromatography, High Pressure Liquid; Diphosphates; Diphosphonates; Diterpenes; DNA Ligases; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Osteoclasts; Polyisoprenyl Phosphates; Polyphosphates; RNA Ligase (ATP); Sesquiterpenes; Substrate Specificity

2009
Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Jun-30, Volume: 106, Issue:26

    Topics: Alkyl and Aryl Transferases; Biosynthetic Pathways; Cloning, Molecular; Cyclohexane Monoterpenes; Dimethylallyltranstransferase; Diphosphates; Diterpenes; DNA, Complementary; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Plant; Gene Library; Hemiterpenes; Kinetics; Molecular Sequence Data; Molecular Structure; Monoterpenes; Organophosphorus Compounds; Plant Epidermis; Plant Proteins; Polyisoprenyl Phosphates; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Solanum lycopersicum; Substrate Specificity

2009
Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients.
    Cancer immunology, immunotherapy : CII, 2010, Volume: 59, Issue:11

    Topics: Adenocarcinoma; Aged; Blotting, Western; Bone Density Conservation Agents; Carcinoma, Hepatocellular; Cell Differentiation; Cell Proliferation; Coculture Techniques; Colorectal Neoplasms; Cytotoxicity, Immunologic; Dendritic Cells; Diphosphates; Diphosphonates; Female; Flow Cytometry; Hemiterpenes; Humans; Imidazoles; Immunotherapy, Adoptive; Liver Neoplasms; Male; Middle Aged; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Zoledronic Acid

2010
Preferential Th1 cytokine profile of phosphoantigen-stimulated human Vγ9Vδ2 T cells.
    Mediators of inflammation, 2010, Volume: 2010

    Topics: Antigens; Cytokines; Diphosphates; Hemiterpenes; Humans; Immunity, Innate; In Vitro Techniques; Interferon-gamma; Interleukins; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Th1 Cells; Tumor Necrosis Factor-alpha

2010
Primary MHC-class II(+) cells are necessary to promote resting Vδ2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Dec-01, Volume: 189, Issue:11

    Topics: Antibodies; Antigens, CD; B-Lymphocytes; Cell Proliferation; Cell Separation; Dendritic Cells; Diphosphates; Gene Expression; Hemiterpenes; Histocompatibility Antigens Class II; Humans; Immunologic Factors; Lymphocyte Activation; Lymphocyte Depletion; Monocytes; Organophosphorus Compounds; Primary Cell Culture; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes

2012
Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
    BMC structural biology, 2012, Dec-12, Volume: 12

    Topics: Catalytic Domain; Crystallography, X-Ray; Diphosphates; Drug Design; Enzyme Inhibitors; Geranyltranstransferase; Hemiterpenes; Humans; Ligands; Models, Molecular; Organophosphorus Compounds; Protein Binding; Protein Structure, Tertiary; Static Electricity

2012
Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Mar-01, Volume: 194, Issue:5

    Topics: Animals; Antigens; Antigens, CD; Binding Sites; Butyrophilins; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Crystallography, X-Ray; Diphosphates; Diphosphonates; Escherichia coli; Gene Expression Regulation; Hemiterpenes; Humans; Imidazoles; Lymphocyte Activation; Membrane Proteins; Models, Molecular; Organophosphorus Compounds; Phosphoproteins; Plakins; Primary Cell Culture; Protein Binding; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes; Two-Hybrid System Techniques; Zoledronic Acid

2015
Monoterpene biosynthesis potential of plant subcellular compartments.
    The New phytologist, 2016, Volume: 209, Issue:2

    Topics: Acyclic Monoterpenes; Cytosol; Diphosphates; Diterpenes; Geranyltranstransferase; Hemiterpenes; Mitochondria; Monoterpenes; Nicotiana; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Picea; Plant Proteins; Plants, Genetically Modified; Plastids; Terpenes; Valerian

2016
A homomeric geranyl diphosphate synthase-encoding gene from Camptotheca acuminata and its combinatorial optimization for production of geraniol in Escherichia coli.
    Journal of industrial microbiology & biotechnology, 2017, Volume: 44, Issue:10

    Topics: Acyclic Monoterpenes; Camptotheca; Diphosphates; Diterpenes; DNA, Complementary; Escherichia coli; Geranyltranstransferase; Hemiterpenes; Monoterpenes; Organophosphorus Compounds; Polyisoprenyl Phosphates; Polymerase Chain Reaction; Sesquiterpenes; Terpenes

2017
Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase.
    FEMS yeast research, 2017, 06-01, Volume: 17, Issue:4

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Diphosphates; Diterpenes; Gene Expression Regulation, Fungal; Geranyltranstransferase; Hemiterpenes; Kinetics; Metabolic Engineering; Molecular Docking Simulation; Organophosphorus Compounds; Point Mutation; Polyisoprenyl Phosphates; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology, Amino Acid; Sesquiterpenes; Substrate Specificity; Terpenes; Thermodynamics

2017
A cryptic activity in the Nudix hydrolase superfamily.
    Protein science : a publication of the Protein Society, 2019, Volume: 28, Issue:8

    Topics: Diphosphates; Escherichia coli; Hemiterpenes; Models, Molecular; Molecular Structure; Nudix Hydrolases; Organophosphorus Compounds; Pyrophosphatases

2019
Identifying Structural Determinants of Product Specificity in
    Biochemistry, 2020, 07-28, Volume: 59, Issue:29

    Topics: Binding Sites; Crystallography, X-Ray; Diphosphates; Diterpenes; Geranyltranstransferase; Hemiterpenes; Humans; Leishmania major; Leishmaniasis, Cutaneous; Models, Molecular; Organophosphorus Compounds; Polyisoprenyl Phosphates; Protein Conformation; Sesquiterpenes; Substrate Specificity

2020
Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway.
    Microbial cell factories, 2022, Oct-15, Volume: 21, Issue:1

    Topics: Acyclic Monoterpenes; Carbon; Diphosphates; DNA Copy Number Variations; Geranyltranstransferase; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Monoterpenes; Organophosphorus Compounds; Pentanols; Saccharomyces cerevisiae

2022