isopentenyl pyrophosphate and mevalonic acid

isopentenyl pyrophosphate has been researched along with mevalonic acid in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (13.04)	18.7374
1990's	20 (21.74)	18.2507
2000's	35 (38.04)	29.6817
2010's	21 (22.83)	24.3611
2020's	4 (4.35)	2.80

Authors

Authors	Studies
Chichester, CO; Hayman, EP; Simpson, KL	1
Gottlieb, D; Wood, SG	1
Lutz, RJ; McLain, TM; Sinensky, M	1
Kawahara, Y; Momose, K; Shimizu, S; Sugawara, H; Yamamoto, T	1
Edorh, GG; Karst, F; Mbaya, B; Rigomier, D; Schrevel, J	1
d'Orchymont, H; Ducep, JB; Jung, MJ; Nave, JF; Piriou, F	1
Havel, C; Rector, ER; Watson, JA	1
Beyer, P; Kleinig, H; Kreuz, K	1
Baker, FC; Havel, CM; Lobos, DV; Morrow, CJ; Watson, JA	1
Ness, GC; Porter, JW; Qureshi, N; Slakey, LL	1
Kleinig, H; Kreuz, K	1
Fujisaki, S; Katsuki, H; Nakanishi, S; Nishino, T; Yabusaki, Y	1
Bhavnani, BR	1
Jones, D; Learned, RM; Re, EB	1
Giron, MD; Havel, CM; Watson, JA	1
Knani, M; Rohmer, M; Sahm, H; Simonin, P; Sutter, B	1
Horbach, S; Sahm, H; Welle, R	1
Disch, A; Lichtenthaler, HK; Rohmer, M; Schwender, J	1
Braun, S; Focke, M; Gröner, R; Lichtenthaler, FW; Lichtenthaler, HK; Müller, C; Schwender, J; Zeidler, J	1
Seto, H	1
Croteau, R; Lange, BM; McCaskill, D; Wildung, MR	1
Paseshnichenko, VA	1
Bach, TJ; Disch, A; Hemmerlin, A; Rohmer, M	1
Disch, A; Lichtenthaler, HK; Müller, C; Rohmer, M; Schwender, J	1
Rohmer, M	1
Kuzuyama, T; Seto, H; Takahashi, S; Watanabe, H	1
Disch, A; Rohmer, M	1
Altincicek, B; Beck, E; Eberl, M; Hintz, M; Jomaa, H; Lichtenthaler, HK; Sanderbrand, S; Soldati, D; Türbachova, I; Weidemeyer, C; Wiesner, J; Zeidler, J	1
Croteau, R; Lange, BM	1
Fliesler, SJ; Keller, RK	1
Kuzuyama, T; Seto, H; Takagi, M; Takahashi, S	2
Boronat, A; Campos, N; Grosdemange-Billiard, C; Hoeffler, JF; Maldonado, C; María Lois, L; Rodríguez-Concepción, M; Rohmer, M	1
Brown, JR; Bryant, AP; Chalker, AF; Gwynn, MN; Holmes, DJ; Ingraham, KA; Iordanescu, S; Rosenberg, M; So, CY; Wilding, EI	1
Fushie, T; Itoh, D; Karunagoda, RP; Katoh, K; Nabeta, K	1
Mushegian, A; Smit, A	1
Baker, JA; Blagg, BS; Eubanks, LM; Hahn, FM; Poulter, CD; Testa, CA	1
Boronat, A; Campos, N; Gallego, F; Lois, LM; Rodríguez-Concepción, M; Sauret-Güeto, S	1
Bacher, A; Eisenreich, W; Rohdich, F	1
Altincicek, B; Beck, E; Hintz, M; Jomaa, H; Kollas, AK; Sanderbrand, S; Wiesner, J	1
Gemünden, C; Lichtenthaler, HK; Schwender, J	1
Lichtenthaler, HK; Zeidler, J	1
Croteau, RB; Ketchum, RE; Lange, BM	1
Bacher, A; Eisenreich, W; Kis, K; Rohdich, F	1
Curtis, IS; Kamiya, Y; Kawaide, H; Kuzuyama, T; Okada, K; Seto, H	1
Burgner, JW; Hedl, M; Rodwell, VW; Sanchez-Neri, B; Stauffacher, CV; Sutherlin, A	1
Berry, A; Hümbelin, M; Jore, J; Li, J; Lin, J; Thomas, A	1
Muranaka, T; Nagata, N; Suzuki, M; Yoshida, S	1
Kato, H; Miyazawa, Y; Muranaka, T; Yoshida, S	1
Kuzuyama, T; Seto, H	1
BLOCH, K; CHAYKIN, S; DE WAARD, A; PHILLIPS, AH	1
RILLING, HC; SALOKANGAS, RA; SAMUELS, LT	1
Rodwell, VW; Sutherlin, A	1
Andersson, S; Boland, W; Dudareva, N; Gatto, N; Gershenzon, J; Orlova, I; Reichelt, M; Rhodes, D	1
Rogers, MJ; Rojas-Navea, J; Thompson, K	1
Jung, KH; Keasling, JD; Kim, JE; Kim, JY; Kim, SW; Lee, JH; Lee, SH; Lee, YM; Shin, YC; Yoon, SH	1
Grochowski, LL; White, RH; Xu, H	1
Aqvist, J; Carlsson, J; Henriksson, LM; Jones, TA; Mowbray, SL; Unge, T	1
Baldoqui, DC; Bolzani, Vda S; Furlan, M; Kato, MJ; Lopes, AA; López, SN	1
Gottlieb, SS; Keasling, JD; Lieu, B; Newman, JD; Withers, ST	1
Towler, MJ; Weathers, PJ	1
Auriola, S; Holen, I; Kuokkanen, J; Mönkkönen, H; Mönkkönen, J; Ottewell, PD	1
Balibar, CJ; Shen, X; Tao, J	1
Demmer, U; Duin, EC; Ermler, U; Hintz, M; Jomaa, H; No, JH; Oldfield, E; Rekittke, I; Röhrich, R; Troschke, K; Warkentin, E; Wiesner, J; Xu, W	1
de Diego, A; Pérez-Zúñiga, FJ; Sillero, A; Sillero, MA; Silva, JA; Tavares, JE	1
Ewering, C; Kroll, J; Reichelt, R; Steinbüchel, A; Steinle, A	1
Auriola, S; Jauhiainen, M; Mönkkönen, H; Mönkkönen, J; Räikkönen, J	1
Auriola, S; Mönkkönen, H; Mönkkönen, J; Räikkönen, J	1
Castells, FB; Mitrofan, LM; Mönkkönen, J; Pelkonen, J	1
Choi, ES; Chung, YR; Keasling, JD; Kim, JY; Kim, SW; Shah, AA; Wang, C; Yoon, SH	1
Barta, ML; Geisbrecht, BV; Herdendorf, TJ; McWhorter, WJ; Miziorko, HM; Skaff, DA	1
Okada, K	1
Boccadoro, M; Bosia, A; Canepari, ME; Castella, B; Coscia, M; Fiore, F; Foglietta, M; Massaia, M; Palumbo, A; Pantaleoni, F; Peola, S; Riganti, C	1
Chang, WC; Liu, HW; Liu, P; Song, H	1
Chen, X; Stephanopoulos, G; Too, HP; Zhang, C; Zhou, K; Zou, R	1
Bentinger, M; Brismar, K; Chojnacki, T; Dallner, G; Danikiewicz, W; Kaczorowska, E; Kania, M; Swiezewska, E; Tekle, M; Wojcik, J	1
Formighieri, C; Melis, A	1
Abbassi, SJ; Khan, BM; Kumari, U; Patel, P; Vishwakarma, RK	1
Busto, R; Cheng, YC; Dávalos, A; de la Peña, G; Gómez-Coronado, D; Hazen, MJ; Jin, JS; Lasunción, MA; Martín Sánchez, C; Martínez-Botas, J; Pérez Martín, JM; Rodríguez-Acebes, S; Suárez, Y; Zhang, W	1
Dudareva, N; Gutensohn, M; Henry, LK; Noel, JP; Thomas, ST	1
Baidoo, E; George, KW; Kang, A; Keasling, JD; Lee, TS; Wang, G	1
Auriola, S; Gonnermann, D; Janssen, O; Kabelitz, D; Lettau, M; Määttä, J; Nerdal, PT; Oberg, HH; Olive, D; Peters, C; Quabius, ES; Sousa, S; Zlatev, H	1
Altabella, T; Andrade, P; Arró, M; Caudepón, D; Ferrer, A; Manzano, D	1
Chen, CL; Mermoud, JC; Paul, LN; Stauffacher, CV; Steussy, CN	1
Dalwadi, MP; Garavaglia, M; King, JR; Minton, NP; Webb, JP	1
Brachfeld, AC; Febvre, HP; Hulko, T; Liman, GLS; Santangelo, TJ	1
Darii, E; de Berardinis, V; Duquesne, K; Iacazio, G; Mariage, A; Peruch, F; Petit, JL; Rico, J	1
Adams, PD; Baidoo, EEK; Beller, HR; Benites, VT; Goh, EB; Kang, A; Keasling, JD; Lee, TS; Mendez-Perez, D; Mukhopadhyay, A	1
Bumpus, NN; Dziedzic, A; Jedlicka, AE; Jhun, H; Liu, HB; Matthews, KA; Prigge, ST; Rajaram, K; Roberts, AD; Swift, RP; Tewari, SG; Wallqvist, A	1
Hemmi, H; Kitsuwa, K; Komeyama, M; Nakayama, A; Okamura, H; Saito, K; Shinada, T; Yasuno, Y	1
Couillaud, J; Duquesne, K; Iacazio, G; Leydet, L	1
Cao, X; Tang, F; Wang, J; Zhang, Y	1

Reviews

9 review(s) available for isopentenyl pyrophosphate and mevalonic acid

Article	Year
[Non-mevalonate pathway. A new pathway for the biosynthesis of isopentenyl diphosphate]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1997, Volume: 42, Issue:16 Topics: Bacteria; Fungi; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Plants; Pyruvic Acid	1997
A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:2 Topics: Bacteria; Chlorophyta; Hemiterpenes; Mevalonic Acid; Models, Chemical; Organophosphorus Compounds; Plants; Terpenes	1998
Isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs? Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1998, Volume: 50 Topics: Anti-Bacterial Agents; Bacteria; Hemiterpenes; Herbicides; Mevalonic Acid; Organophosphorus Compounds	1998
Deoxyxylulose phosphate pathway to terpenoids. Trends in plant science, 2001, Volume: 6, Issue:2 Topics: Diphosphates; Enzymes; Genes, Bacterial; Genes, Plant; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Terpenes; Xylulose	2001
The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates. Current opinion in chemical biology, 2001, Volume: 5, Issue:5 Topics: Archaea; Bacteria; Chlorophyta; Genes, Bacterial; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pyruvic Acid	2001
Diversity of the biosynthesis of the isoprene units. Natural product reports, 2003, Volume: 20, Issue:2 Topics: Actinomyces; Butadienes; Carbon-Carbon Double Bond Isomerases; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pentanes; Terpenes	2003
The biosynthesis of isoprenoids and the mechanisms regulating it in plants. Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:7 Topics: Arabidopsis; Basic-Leucine Zipper Transcription Factors; Diterpenes; Gene Expression Regulation, Plant; Hemiterpenes; Mevalonic Acid; Multigene Family; Organophosphorus Compounds; Oryza; Phytoalexins; Plants, Genetically Modified; Plastids; Sesquiterpenes; Terpenes	2011
Current development in isoprenoid precursor biosynthesis and regulation. Current opinion in chemical biology, 2013, Volume: 17, Issue:4 Topics: Animals; Biosynthetic Pathways; Hemiterpenes; Humans; Mevalonic Acid; Organophosphorus Compounds; Terpenes	2013
The Terpene Mini-Path, a New Promising Alternative for Terpenoids Bio-Production. Genes, 2021, 12-10, Volume: 12, Issue:12 Topics: Erythritol; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Terpenes	2021

Other Studies

83 other study(ies) available for isopentenyl pyrophosphate and mevalonic acid

Article	Year
Mechanism of the isomerization of isopentenyl pyrophosphate in Rhodotorual rubra-1. Journal of bacteriology, 1975, Volume: 123, Issue:1 Topics: Alkenes; Carotenoids; Hemiterpenes; Isomerases; Isomerism; Mevalonic Acid; Mitosporic Fungi; Organophosphorus Compounds; Phosphoric Acids; Rhodotorula; Transferases	1975
Evidence from cell-free systems for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. The Biochemical journal, 1978, Feb-15, Volume: 170, Issue:2 Topics: Alkenes; Cell-Free System; Chromatography, Ion Exchange; Fungi; Hemiterpenes; Iodoacetamide; Mevalonic Acid; Mitosporic Fungi; Organophosphorus Compounds; Phytophthora; Rhizoctonia; Squalene; Sterols	1978
Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. The Journal of biological chemistry, 1992, Apr-25, Volume: 267, Issue:12 Topics: Animals; Carbon-Carbon Double Bond Isomerases; Cell-Free System; Chromatography, High Pressure Liquid; Feedback; Hemiterpenes; Isomerases; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Proteins; Rabbits; Sesquiterpenes	1992
Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. Archives of biochemistry and biophysics, 1991, Volume: 284, Issue:1 Topics: Animals; Diphosphates; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Iodoacetamide; Isoproterenol; Mevalonic Acid; Mitochondria, Heart; Myocardium; Organophosphorus Compounds; Polyisoprenyl Phosphates; Rats; Rats, Inbred Strains; Terpenes; Ubiquinone	1991
Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria. Biochemical and biophysical research communications, 1990, Dec-31, Volume: 173, Issue:3 Topics: Acetates; Animals; Cells, Cultured; Erythrocytes; Hemiterpenes; Humans; Malaria; Mevalonic Acid; Organophosphorus Compounds; Plasmodium falciparum; Polyisoprenyl Phosphates; Saccharomyces cerevisiae; Sesquiterpenes	1990
Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. The Biochemical journal, 1985, Apr-01, Volume: 227, Issue:1 Topics: Animals; Anticholesteremic Agents; Carboxy-Lyases; Cholesterol; Chromatography, Thin Layer; Hemiterpenes; In Vitro Techniques; Kinetics; Lipids; Liver; Mevalonic Acid; Organophosphorus Compounds; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Rats; Rats, Inbred Strains	1985
Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. The Journal of biological chemistry, 1986, Aug-05, Volume: 261, Issue:22 Topics: Alcohols; Animals; Carbon Radioisotopes; Cell Line; Drosophila; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mevalonic Acid; NAD; Organophosphorus Compounds; Structure-Activity Relationship; Substrate Specificity; Tritium	1986
Separation of mevalonate phosphates and isopentenyl pyrophosphate by thin-layer chromatography and of short-chain prenyl phosphates by ion-pair chromatography on a high-performance liquid chromatography column. Methods in enzymology, 1985, Volume: 111 Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hemiterpenes; Indicators and Reagents; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Structure-Activity Relationship	1985
Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26 Topics: Animals; Cell Line; Drosophila; Hemiterpenes; Hot Temperature; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Protein Biosynthesis	1985
Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. Journal of lipid research, 1973, Volume: 14, Issue:4 Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Alkenes; Animals; Aorta; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Paper; Coenzyme A; Farnesol; Glutarates; Hemiterpenes; Ligases; Mevalonic Acid; Multienzyme Complexes; Muscle, Smooth; Organophosphorus Compounds; Phosphoric Acids; Squalene; Subcellular Fractions; Swine	1973
Synthesis of prenyl lipids in cells of spinach leaf. Compartmentation of enzymes for formation of isopentenyl diphosphate. European journal of biochemistry, 1984, Jun-15, Volume: 141, Issue:3 Topics: Cell Compartmentation; Chloroplasts; Cytoplasm; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Mevalonic Acid; Microsomes; NADPH-Ferrihemoprotein Reductase; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Plants	1984
Preparation of 14C-labeled and unlabeled sterol intermediates from yeast using metabolic inhibitors. Journal of biochemistry, 1984, Volume: 96, Issue:6 Topics: Anaerobiosis; Cholesterol; Ethionine; Hemiterpenes; Lanosterol; Mevalonic Acid; Organophosphorus Compounds; Saccharomyces cerevisiae; Sterols	1984
Oestrogen biosynthesis in the pregnant mare. The Journal of endocrinology, 1981, Volume: 89 Suppl Topics: Acetates; Alkenes; Androstenedione; Animals; Chemical Phenomena; Chemistry; Cholesterol; Dehydroepiandrosterone; Equilin; Estrogens; Farnesol; Female; Hemiterpenes; Horses; Maternal-Fetal Exchange; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Pregnancy; Pregnancy, Animal; Sesquiterpenes; Squalene; Tyrosine	1981
Co-expression of native and introduced genes reveals cryptic regulation of HMG CoA reductase expression in Arabidopsis. The Plant journal : for cell and molecular biology, 1995, Volume: 7, Issue:5 Topics: Arabidopsis; Base Sequence; Enzyme Induction; Gene Expression Regulation, Plant; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Plant Proteins; Plants, Genetically Modified; Recombinant Fusion Proteins; RNA, Messenger; RNA, Plant	1995
Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1 Topics: Cell Line; Fatty Acids, Unsaturated; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Lactones; Mevalonic Acid; Organophosphorus Compounds; Protein Processing, Post-Translational	1993
Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. The Biochemical journal, 1993, Oct-15, Volume: 295 ( Pt 2) Topics: Bacteria; Carbon Isotopes; Hemiterpenes; Magnetic Resonance Spectroscopy; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Terpenes	1993
Isoprenoid biosynthesis in bacteria: two different pathways? FEMS microbiology letters, 1993, Aug-01, Volume: 111, Issue:2-3 Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacteria; Escherichia coli; Halobacterium; Hemiterpenes; Lactobacillus; Mevalonic Acid; Myxococcus; Organophosphorus Compounds; Species Specificity; Staphylococcus; Terpenes; Zymomonas	1993
Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. FEBS letters, 1997, Jan-06, Volume: 400, Issue:3 Topics: beta Carotene; Chloroplasts; Cytoplasm; Glyceraldehyde 3-Phosphate; Hemiterpenes; Lutein; Magnetic Resonance Spectroscopy; Mevalonic Acid; Organophosphorus Compounds; Phytol; Plastoquinone; Pyruvic Acid	1997
Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. FEBS letters, 1997, Sep-01, Volume: 414, Issue:1 Topics: Butadienes; Carbon Isotopes; Chlorophyta; Deuterium; Eukaryota; Glycosides; Hemiterpenes; Magnetic Resonance Spectroscopy; Magnoliopsida; Mevalonic Acid; Molecular Structure; Organophosphorus Compounds; Pentanes; Phytol; Rhodophyta; Sterols; Xylulose	1997
A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5 Topics: Amino Acid Sequence; Consensus Sequence; Escherichia coli; Evolution, Molecular; Gas Chromatography-Mass Spectrometry; Hemiterpenes; Humans; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Phylogeny; Plant Leaves; Plants, Edible; Polyisoprenyl Phosphate Monosaccharides; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transferases; Transketolase	1998
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2) Topics: Acetyl Coenzyme A; Carbon Isotopes; Cell Line; Coenzymes; Glucose; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Mitochondria; Nicotiana; Organophosphorus Compounds; Plants, Toxic; Plastoquinone; Polyisoprenyl Phosphates; Pyruvic Acid; Sterols; Ubiquinone	1998
Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. The Biochemical journal, 1998, Jul-15, Volume: 333 ( Pt 2) Topics: Animals; Chlamydomonas reinhardtii; Chlorella; Chloroplasts; Cyanobacteria; Euglena gracilis; Eukaryota; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Models, Chemical; Organophosphorus Compounds; Polyisoprenyl Phosphates; Pyruvic Acid	1998
A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America, 1998, Aug-18, Volume: 95, Issue:17 Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Primers; Erythritol; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Multienzyme Complexes; Mutation; Organophosphorus Compounds; Oxidoreductases; Pentosephosphates; Polyisoprenyl Phosphates; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid; Sugar Phosphates	1998
On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. FEMS microbiology letters, 1998, Nov-15, Volume: 168, Issue:2 Topics: Acetates; beta Carotene; Carbon Isotopes; Ergosterol; Glucose; Glyceraldehyde 3-Phosphate; Hemiterpenes; Hypocreales; Mevalonic Acid; Organophosphorus Compounds; Pyruvates; Rhodotorula; Triterpenes; Ubiquinone	1998
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433 Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme Inhibitors; Fosfomycin; Genes, Protozoan; Hemiterpenes; Malaria; Malaria, Falciparum; Mevalonic Acid; Mice; Molecular Sequence Data; Multienzyme Complexes; Organelles; Organophosphorus Compounds; Oxidoreductases; Pentosephosphates; Plasmodium falciparum; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Terpenes	1999
Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24 Topics: Amino Acid Sequence; Base Sequence; Catalysis; Cloning, Molecular; DNA, Plant; Escherichia coli; Gene Expression; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Plants, Medicinal; Protein Kinases; Recombinant Fusion Proteins; Sequence Analysis, DNA	1999
Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. Biochemical and biophysical research communications, 1999, Dec-20, Volume: 266, Issue:2 Topics: Alendronate; Alkyl and Aryl Transferases; Animals; Chromatography, High Pressure Liquid; Cytosol; Geranyltranstransferase; Hemiterpenes; Kinetics; Liver; Male; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Rats; Rats, Sprague-Dawley; Sesquiterpenes	1999
Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis. Journal of bacteriology, 2000, Volume: 182, Issue:4 Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Sequence Alignment; Sequence Analysis, DNA; Streptomyces; Transferases	2000
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. FEBS letters, 2000, May-19, Volume: 473, Issue:3 Topics: Arabinose; Carbon-Carbon Double Bond Isomerases; Escherichia coli; Hemiterpenes; Mevalonic Acid; Mutagenesis, Insertional; Organophosphorus Compounds; Polymerase Chain Reaction	2000
A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. Journal of bacteriology, 2000, Volume: 182, Issue:15 Topics: Antigens, Bacterial; Escherichia coli; Fosfomycin; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Isopropyl Thiogalactoside; Magnetic Resonance Spectroscopy; Mevalonic Acid; Models, Chemical; Open Reading Frames; Organophosphorus Compounds; Sequence Analysis, DNA; Streptomyces	2000
Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci. Journal of bacteriology, 2000, Volume: 182, Issue:15 Topics: Acetyl-CoA C-Acetyltransferase; Alleles; Amino Acid Sequence; Animals; Carboxy-Lyases; Cells, Cultured; Gram-Positive Cocci; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Mevalonic Acid; Mice; Molecular Sequence Data; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Phylogeny; Streptococcus pneumoniae	2000
Nonequivalent labeling of the phytyl side chain of chlorophyll a in callus of the hornwort Anthoceros punctatus. Journal of natural products, 2000, Volume: 63, Issue:8 Topics: Antioxidants; Chlorophyll; Chlorophyll A; Chromatography, Agarose; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cinnamates; Depsides; Hemiterpenes; Isotope Labeling; Magnetic Resonance Spectroscopy; Mevalonic Acid; Optical Rotation; Organophosphorus Compounds; Plants; Polyisoprenyl Phosphates; Rosmarinic Acid; Sesquiterpenes	2000
Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. Genome research, 2000, Volume: 10, Issue:10 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Archaea; Archaeal Proteins; Bacterial Proteins; Conserved Sequence; Evolution, Molecular; Genetic Linkage; Hemiterpenes; Humans; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Pentosephosphates; Phylogeny; Plant Proteins; Polyisoprenyl Phosphate Sugars; Sequence Alignment; Sequence Homology, Amino Acid	2000
1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. Journal of bacteriology, 2001, Volume: 183, Issue:1 Topics: Amino Acid Sequence; Dimerization; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Open Reading Frames; Organophosphorus Compounds; Recombinant Proteins; Rhodobacter capsulatus; Sequence Alignment; Transferases	2001
Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. The Biochemical journal, 2001, Jan-01, Volume: 353, Issue:Pt 1 Topics: Bacterial Proteins; Carbon-Carbon Double Bond Isomerases; Carboxy-Lyases; Chromosomes, Bacterial; DNA, Recombinant; Erythritol; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, Bacterial; Genes, Essential; Genes, Fungal; Genes, Lethal; Genetic Engineering; Hemiterpenes; Humans; Mevalonic Acid; Nucleotidyltransferases; Operon; Organophosphorus Compounds; Phenotype; Phosphorus-Oxygen Lyases; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Polyisoprenyl Phosphates; Recombination, Genetic; Sugar Phosphates	2001
GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. Journal of bacteriology, 2001, Volume: 183, Issue:8 Topics: Amino Acid Sequence; Bacterial Proteins; Enzymes; Erythritol; Escherichia coli; Gene Deletion; Genetic Complementation Test; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Sugar Phosphates	2001
Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. Planta, 2001, Volume: 212, Issue:3 Topics: Carbon Radioisotopes; Chlorophyta; Deuterium; Erythritol; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pentosephosphates; Phytol; Polyisoprenyl Phosphates; Sterols; Sugar Phosphates; Xylulose	2001
Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. Planta, 2001, Volume: 213, Issue:2 Topics: Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pentanols; Pinus; Pinus ponderosa; Terpenes; Xylulose	2001
Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. Plant physiology, 2001, Volume: 127, Issue:1 Topics: Binding Sites; Carbon Radioisotopes; Chromatography, Liquid; Cytosol; Hemiterpenes; Herbicides; Lamiaceae; Mass Spectrometry; Mentha piperita; Mevalonic Acid; Organophosphorus Compounds; Plant Oils; Plant Structures; Plastids; Pyruvic Acid; Terpenes	2001
Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. Planta, 2002, Volume: 215, Issue:2 Topics: Aldose-Ketose Isomerases; Arabidopsis; Carotenoids; Chlorophyll; Chlorophyll A; Chloroplasts; Cloning, Molecular; Diterpenes; Diterpenes, Kaurane; DNA, Antisense; Fosfomycin; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Multienzyme Complexes; Nucleotidyltransferases; Organophosphorus Compounds; Oxidoreductases; Phenotype; Pigments, Biological; Plants, Genetically Modified	2002
Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis. Journal of bacteriology, 2002, Volume: 184, Issue:15 Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Antigens, Bacterial; Coenzyme A Ligases; Enterococcus faecalis; Escherichia coli; Genetic Vectors; Hemiterpenes; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Magnesium Chloride; Mevalonic Acid; Molecular Sequence Data; Molecular Weight; Organophosphorus Compounds; Recombinant Proteins; Temperature	2002
Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. Gene, 2002, Sep-04, Volume: 297, Issue:1-2 Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Sequence; Bacterial Proteins; Carbon-Carbon Double Bond Isomerases; DNA, Bacterial; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Membrane Proteins; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Paracoccus; Polyisoprenyl Phosphates; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sesquiterpenes; Terpenes	2002
Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. Planta, 2002, Volume: 216, Issue:2 Topics: Arabidopsis; Chlorophyll; Chloroplasts; Darkness; Erythritol; Hemiterpenes; Light; Lovastatin; Mevalonic Acid; Microscopy, Electron; Mutation; Organophosphorus Compounds; Plastids; Sugar Phosphates	2002
Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. Plant & cell physiology, 2002, Volume: 43, Issue:12 Topics: 2,4-Dichlorophenoxyacetic Acid; Adenine; Adenosine; Benzyl Compounds; Cells, Cultured; Cytokinins; Gene Expression Regulation; Glucose-1-Phosphate Adenylyltransferase; Hemiterpenes; Isopentenyladenosine; Kinetin; Lovastatin; Mass Spectrometry; Mevalonic Acid; Nicotiana; Nucleotidyltransferases; Organophosphorus Compounds; Plant Growth Regulators; Plastids; Purines; RNA, Messenger; Starch; Zeatin	2002
Mevalonic acid pyrophosphate and isopentenylpyrophosphate. The Journal of biological chemistry, 1959, Volume: 234 Topics: Diphosphates; Fatty Acids; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds	1959
TERPENE METABOLISM IN THE RAT TESTIS. I. THE CONVERSION OF ISOPENTENYL PYROPHOSPHATE TO SQUALENE AND STEROLS. Biochemistry, 1964, Volume: 3 Topics: Carbon Isotopes; Cholesterol; Chromatography; Diphosphates; Fishes; Hemiterpenes; Humans; Lipid Metabolism; Male; Metabolism; Mevalonic Acid; NADP; Organophosphorus Compounds; Rats; Research; Saccharomyces; Squalene; Sterols; Terpenes; Testis	1964
Multienzyme mevalonate pathway bioreactor. Biotechnology and bioengineering, 2004, Aug-20, Volume: 87, Issue:4 Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Bioreactors; Enterococcus faecalis; Enzyme Activation; Enzymes, Immobilized; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Mevalonic Acid; Multienzyme Complexes; Organophosphorus Compounds; Recombinant Proteins	2004
The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. Proceedings of the National Academy of Sciences of the United States of America, 2005, Jan-18, Volume: 102, Issue:3 Topics: Antirrhinum; Base Sequence; Circadian Rhythm; Cytosol; Erythritol; Flowers; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Monoterpenes; Organophosphorus Compounds; Plastids; Sesquiterpenes; Sugar Phosphates	2005
Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. Blood, 2006, Jan-15, Volume: 107, Issue:2 Topics: Animals; Butylamines; Cell Proliferation; Geranyltranstransferase; Hemiterpenes; Lovastatin; Lymphocyte Activation; Macrophages; Mevalonic Acid; Mice; Organophosphorus Compounds; Propylamines; Protein Prenylation; rap1 GTP-Binding Proteins; Signal Transduction; T-Lymphocyte Subsets; T-Lymphocytes	2006
Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. Biotechnology and bioengineering, 2006, Aug-20, Volume: 94, Issue:6 Topics: Carotenoids; Cell Culture Techniques; Cloning, Molecular; Escherichia coli; Genetic Enhancement; Hemiterpenes; Lycopene; Mevalonic Acid; Organophosphorus Compounds; Protein Engineering; Recombinant Proteins	2006
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. Journal of bacteriology, 2006, Volume: 188, Issue:9 Topics: Archaeal Proteins; Hemiterpenes; Methanococcaceae; Mevalonic Acid; Organophosphorus Compounds; Phosphotransferases	2006
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. The Journal of biological chemistry, 2007, Jul-06, Volume: 282, Issue:27 Topics: Aldose-Ketose Isomerases; Amino Acid Substitution; Animals; Bacterial Proteins; Binding Sites; Eukaryota; Fosfomycin; Hemiterpenes; Humans; Ligands; Manganese; Mevalonic Acid; Models, Molecular; Multienzyme Complexes; Mutation, Missense; Mycobacterium tuberculosis; NADP; Organophosphorus Compounds; Oxidation-Reduction; Oxidoreductases; Protein Structure, Quaternary; Terpenes; Xylulose	2007
Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). Phytochemistry, 2007, Volume: 68, Issue:15 Topics: Benzoates; Erythritol; Glucose; Hemiterpenes; Mevalonic Acid; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Piper; Plant Leaves; Plant Roots; Sugar Phosphates; Terpenes	2007
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. Applied and environmental microbiology, 2007, Volume: 73, Issue:19 Topics: Alkyl and Aryl Transferases; Bacillus subtilis; Butadienes; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Engineering; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pentanes; Pentanols; Terpenes	2007
Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. Plant cell reports, 2007, Volume: 26, Issue:12 Topics: Antimalarials; Artemisia annua; Artemisinins; Biomass; Carbon; Cotyledon; Cytosol; Hemiterpenes; Lovastatin; Mevalonic Acid; Miconazole; Models, Biological; Organophosphorus Compounds; Plastids	2007
Zoledronic acid-induced IPP/ApppI production in vivo. Life sciences, 2007, Sep-08, Volume: 81, Issue:13 Topics: Adenosine Triphosphate; Animals; Bone Density Conservation Agents; Bone Marrow Cells; Bone Resorption; Cells, Cultured; Diphosphonates; Geranyltranstransferase; Hemiterpenes; Imidazoles; Macrophages, Peritoneal; Mevalonic Acid; Mice; Organophosphorus Compounds; Time Factors; Zoledronic Acid	2007
The mevalonate pathway of Staphylococcus aureus. Journal of bacteriology, 2009, Volume: 191, Issue:3 Topics: Glycolysis; Hemiterpenes; Mevalonic Acid; Microbial Viability; Oligonucleotide Array Sequence Analysis; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Staphylococcus aureus; Transcription, Genetic	2009
Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. Journal of the American Chemical Society, 2008, Dec-24, Volume: 130, Issue:51 Topics: Amino Acid Sequence; Animals; Bacteria; Catalysis; Evolution, Molecular; Hemiterpenes; Mevalonic Acid; Models, Chemical; Molecular Conformation; Molecular Sequence Data; Organophosphorus Compounds; Oxidoreductases; Plasmodium falciparum; Sequence Homology, Amino Acid; Terpenes	2008
Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Biochemical pharmacology, 2009, Aug-15, Volume: 78, Issue:4 Topics: Adenosine Triphosphate; Animals; Binding Sites; Chromatography, High Pressure Liquid; Diphosphates; Diphosphonates; Diterpenes; DNA Ligases; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Osteoclasts; Polyisoprenyl Phosphates; Polyphosphates; RNA Ligase (ATP); Sesquiterpenes; Substrate Specificity	2009
Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. Metabolic engineering, 2009, Volume: 11, Issue:3 Topics: Acyl Coenzyme A; Anti-Bacterial Agents; Bacterial Proteins; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genetic Engineering; Hemiterpenes; Mevalonic Acid; Mutation; Organophosphorus Compounds; Oxidoreductases; Peptide Synthases; Plasmids; Staphylococcus aureus	2009
Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27 Topics: Adenosine Triphosphate; Breast Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Drug Stability; Hemiterpenes; Humans; Linear Models; Mevalonic Acid; Organophosphorus Compounds; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2009
Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. Biochemical pharmacology, 2010, Mar-01, Volume: 79, Issue:5 Topics: Adenosine Triphosphate; Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Diphosphonates; Down-Regulation; Drug Screening Assays, Antitumor; Farnesol; Female; Gene Expression Regulation, Neoplastic; Hemiterpenes; Humans; Imidazoles; Mevalonic Acid; Organophosphorus Compounds; Zoledronic Acid	2010
Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. The Journal of biological chemistry, 2010, Jan-15, Volume: 285, Issue:3 Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-X Protein; Caspase Inhibitors; Cathepsins; Cattle; Cell Line, Tumor; Cell Membrane Permeability; Diphosphonates; Hemiterpenes; Humans; Imidazoles; Lymphoma, Follicular; Lysosomes; Mevalonic Acid; Mice; Mitochondria; Organophosphorus Compounds; Prenylation; Protease Inhibitors; Signal Transduction; Zoledronic Acid	2010
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. Biotechnology and bioengineering, 2010, Oct-15, Volume: 107, Issue:3 Topics: Culture Media; Escherichia coli; Farnesol; Gene Dosage; Gene Expression; Geranyltranstransferase; Hemiterpenes; Metabolic Networks and Pathways; Mevalonic Acid; Organophosphorus Compounds; Plasmids; Polyisoprenyl Phosphates; Sesquiterpenes	2010
Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. The Journal of biological chemistry, 2011, Jul-08, Volume: 286, Issue:27 Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Crystallography, X-Ray; Hemiterpenes; Mevalonic Acid; Mutation, Missense; Organophosphorus Compounds; Staphylococcus epidermidis; Structure-Activity Relationship; Substrate Specificity	2011
Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. Journal of immunology (Baltimore, Md. : 1950), 2011, Aug-15, Volume: 187, Issue:4 Topics: B7-1 Antigen; Bone Density Conservation Agents; CD8-Positive T-Lymphocytes; Cell Communication; Cell Proliferation; Dendritic Cells; Diphosphonates; Gene Expression Regulation; Hemiterpenes; Humans; Imidazoles; Lymphocyte Activation; Mevalonic Acid; Monocytes; Multiple Myeloma; Organophosphorus Compounds; Programmed Cell Death 1 Ligand 2 Protein; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Zoledronic Acid	2011
Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. PloS one, 2013, Volume: 8, Issue:11 Topics: Alkyl and Aryl Transferases; Geranyltranstransferase; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Polycyclic Sesquiterpenes; Polyisoprenyl Phosphates; Research Design; Sesquiterpenes	2013
Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis. Biochimica et biophysica acta, 2014, Volume: 1841, Issue:7 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Diabetes Mellitus, Experimental; Etidronic Acid; Hemiterpenes; Hep G2 Cells; Humans; Lovastatin; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Organophosphorus Compounds; Rats; Rats, Wistar; Risedronic Acid; Squalene; Tricarboxylic Acids; Ubiquinone	2014
Carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in Escherichia coli cultures. Archives of microbiology, 2014, Volume: 196, Issue:12 Topics: Biosynthetic Pathways; Carbon; Cyclohexane Monoterpenes; Cyclohexenes; Erythritol; Escherichia coli; Escherichia coli Proteins; Hemiterpenes; Lavandula; Mevalonic Acid; Monoterpenes; Organophosphorus Compounds; Picea; Recombinant Proteins; Sugar Phosphates; Synechocystis; Terpenes; Transformation, Bacterial	2014
Bacopa monniera recombinant mevalonate diphosphate decarboxylase: Biochemical characterization. International journal of biological macromolecules, 2015, Volume: 79 Topics: Bacopa; Carboxy-Lyases; Cations, Divalent; Cloning, Molecular; Enzyme Assays; Enzyme Stability; Escherichia coli; Gene Expression; Hemiterpenes; Hydrogen-Ion Concentration; Kinetics; Magnesium; Mevalonic Acid; Molecular Weight; Organophosphorus Compounds; Plant Proteins; Recombinant Proteins; Temperature	2015
Disruption of the mevalonate pathway induces dNTP depletion and DNA damage. Biochimica et biophysica acta, 2015, Volume: 1851, Issue:9 Topics: Adenosine Triphosphate; Carboxy-Lyases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Deoxyribonucleosides; DNA Damage; DNA Replication; Gene Expression Regulation; Halogenation; Hemiterpenes; Histones; HL-60 Cells; Humans; Lymphocytes; Mevalonic Acid; Organophosphorus Compounds; Protein Kinases; RNA, Small Interfering; Signal Transduction	2015
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-11, Volume: 112, Issue:32 Topics: Arabidopsis; Arabidopsis Proteins; Archaea; Cytosol; Gene Expression Regulation, Plant; Gene Knockout Techniques; Genes, Plant; Hemiterpenes; Kinetics; Metabolic Networks and Pathways; Mevalonic Acid; Nicotiana; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Plants, Genetically Modified; Plastids; Polyisoprenyl Phosphates; Sequence Homology, Amino Acid; Sesquiterpenes; Terpenes	2015
Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production. Metabolic engineering, 2016, Volume: 34 Topics: Escherichia coli; Escherichia coli Proteins; Hemiterpenes; Metabolic Engineering; Metabolic Flux Analysis; Metabolic Networks and Pathways; Metabolome; Mevalonic Acid; Organophosphorus Compounds; Pentanols; Signal Transduction	2016
Butyrophilin 3A/CD277-Dependent Activation of Human γδ T Cells: Accessory Cell Capacity of Distinct Leukocyte Populations. Journal of immunology (Baltimore, Md. : 1950), 2016, 10-15, Volume: 197, Issue:8 Topics: Antibodies, Blocking; Antigens, CD; Butyrophilins; CD4-Positive T-Lymphocytes; Cells, Cultured; Diphosphonates; Geranyltranstransferase; Hemiterpenes; Humans; Imidazoles; Interleukin-18; Lymphocyte Activation; Mevalonic Acid; Monocytes; Neutrophils; Organophosphates; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Zoledronic Acid	2016
Complex interplays between phytosterols and plastid development. Plant signaling & behavior, 2017, Nov-02, Volume: 12, Issue:11 Topics: Arabidopsis; Chloroplasts; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Phytosterols; Plastids	2017
Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen The Journal of biological chemistry, 2017, 12-29, Volume: 292, Issue:52 Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Crystallography, X-Ray; Enterococcus faecalis; Hemiterpenes; Kinetics; Mevalonic Acid; Organophosphorus Compounds; Substrate Specificity	2017
Applying asymptotic methods to synthetic biology: Modelling the reaction kinetics of the mevalonate pathway. Journal of theoretical biology, 2018, 02-14, Volume: 439 Topics: Acyl Coenzyme A; Hemiterpenes; Kinetics; Metabolic Networks and Pathways; Mevalonic Acid; Models, Theoretical; Organophosphorus Compounds; Synthetic Biology; Terpenes	2018
A linear pathway for mevalonate production supports growth of Thermococcus kodakarensis. Extremophiles : life under extreme conditions, 2019, Volume: 23, Issue:2 Topics: Acetyl Coenzyme A; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Thermococcus	2019
Exploring natural biodiversity to expand access to microbial terpene synthesis. Microbial cell factories, 2019, Feb-01, Volume: 18, Issue:1 Topics: Archaea; Bacteria; Batch Cell Culture Techniques; Biodiversity; Carotenoids; Erythritol; Escherichia coli; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Organophosphorus Compounds; Terpenes	2019
Optimization of the IPP-bypass mevalonate pathway and fed-batch fermentation for the production of isoprenol in Escherichia coli. Metabolic engineering, 2019, Volume: 56 Topics: Batch Cell Culture Techniques; Carboxy-Lyases; Escherichia coli; Escherichia coli Proteins; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Organophosphorus Compounds	2019
A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites. PLoS pathogens, 2020, Volume: 16, Issue:2 Topics: Animals; Anti-Bacterial Agents; Apicoplasts; Azithromycin; Fosfomycin; Hemiterpenes; Humans; Malaria; Mevalonic Acid; Organophosphorus Compounds; Parasites; Plasmodium falciparum; Plastids; Protozoan Proteins	2020
Total Synthesis and Structure Confirmation of Journal of natural products, 2021, 10-22, Volume: 84, Issue:10 Topics: Aeropyrum; Hemiterpenes; Hydro-Lyases; Mevalonic Acid; Molecular Structure; Organophosphates; Organophosphorus Compounds; Terpenes	2021
Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway. Microbial cell factories, 2022, Oct-15, Volume: 21, Issue:1 Topics: Acyclic Monoterpenes; Carbon; Diphosphates; DNA Copy Number Variations; Geranyltranstransferase; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Monoterpenes; Organophosphorus Compounds; Pentanols; Saccharomyces cerevisiae	2022