isopentenyl pyrophosphate and fosmidomycin

isopentenyl pyrophosphate has been researched along with fosmidomycin in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (14.29)	18.2507
2000's	5 (35.71)	29.6817
2010's	6 (42.86)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Hirsch, AK; Masini, T	1
Altincicek, B; Beck, E; Eberl, M; Hintz, M; Jomaa, H; Lichtenthaler, HK; Sanderbrand, S; Soldati, D; Türbachova, I; Weidemeyer, C; Wiesner, J; Zeidler, J	1
Ridley, RG	1
Kuzuyama, T; Seto, H; Takagi, M; Takahashi, S	1
Curtis, IS; Kamiya, Y; Kawaide, H; Kuzuyama, T; Okada, K; Seto, H	1
Cunningham, FX; Ershov, YV; Gantt, E; Gantt, RR	1
Chang, HS; Fürholz, A; Gruissem, W; Heifetz, PB; Lange, M; Laule, O; Wang, X; Zhu, T	1
Aqvist, J; Carlsson, J; Henriksson, LM; Jones, TA; Mowbray, SL; Unge, T	1
Hunter, WN	1
DeRisi, JL; Yeh, E	1
Fall, R; Rosenstiel, TN; Sivy, TL	1
Bowman, JD; Brooks, CF; Carlier, PR; Cassera, MB; Merino, EF; Striepen, B	1
Cope, EK; Dhungana, S; Finney, KB; Fox, DT; Koppisch, AT; Leid, JG; Phillips, PD; Schmidt, EN; Testa, CA; Tian, H; Valentine, MC; Warrington, NV	1
Bumpus, NN; Dziedzic, A; Jedlicka, AE; Jhun, H; Liu, HB; Matthews, KA; Prigge, ST; Rajaram, K; Roberts, AD; Swift, RP; Tewari, SG; Wallqvist, A	1

Reviews

2 review(s) available for isopentenyl pyrophosphate and fosmidomycin

Article	Year
Development of inhibitors of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway enzymes as potential anti-infective agents. Journal of medicinal chemistry, 2014, Dec-11, Volume: 57, Issue:23 Topics: Aldose-Ketose Isomerases; Anti-Infective Agents; Drug Design; Enzyme Inhibitors; Erythritol; Escherichia coli Proteins; Models, Molecular; Multienzyme Complexes; Oxidoreductases; Phosphorus-Oxygen Lyases; Phosphotransferases (Alcohol Group Acceptor); Sugar Phosphates	2014
Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:16 Topics: Animals; Antiprotozoal Agents; Apicomplexa; Bacteria; Drug Delivery Systems; Drug Discovery; Enzyme Inhibitors; Enzyme Precursors; Escherichia coli Proteins; Fosfomycin; Hemiterpenes; Humans; Models, Molecular; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Protozoan Infections; Protozoan Proteins; Radiography; Terpenes	2011

Article

Year

Development of inhibitors of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway enzymes as potential anti-infective agents.

Journal of medicinal chemistry, 2014, Dec-11, Volume: 57, Issue:23

Topics: Aldose-Ketose Isomerases; Anti-Infective Agents; Drug Design; Enzyme Inhibitors; Erythritol; Escherichia coli Proteins; Models, Molecular; Multienzyme Complexes; Oxidoreductases; Phosphorus-Oxygen Lyases; Phosphotransferases (Alcohol Group Acceptor); Sugar Phosphates

2014

Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites.

Current topics in medicinal chemistry, 2011, Volume: 11, Issue:16

Topics: Animals; Antiprotozoal Agents; Apicomplexa; Bacteria; Drug Delivery Systems; Drug Discovery; Enzyme Inhibitors; Enzyme Precursors; Escherichia coli Proteins; Fosfomycin; Hemiterpenes; Humans; Models, Molecular; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Protozoan Infections; Protozoan Proteins; Radiography; Terpenes

2011

Other Studies

12 other study(ies) available for isopentenyl pyrophosphate and fosmidomycin

Article	Year
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433 Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme Inhibitors; Fosfomycin; Genes, Protozoan; Hemiterpenes; Malaria; Malaria, Falciparum; Mevalonic Acid; Mice; Molecular Sequence Data; Multienzyme Complexes; Organelles; Organophosphorus Compounds; Oxidoreductases; Pentosephosphates; Plasmodium falciparum; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Terpenes	1999
Planting the seeds of new antimalarial drugs. Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433 Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Drug Design; Enzyme Inhibitors; Fosfomycin; Hemiterpenes; Humans; Malaria; Malaria, Falciparum; Mice; Multienzyme Complexes; Organelles; Organophosphorus Compounds; Oxidoreductases; Plasmodium falciparum; Steroids; Transferases	1999
A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. Journal of bacteriology, 2000, Volume: 182, Issue:15 Topics: Antigens, Bacterial; Escherichia coli; Fosfomycin; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Isopropyl Thiogalactoside; Magnetic Resonance Spectroscopy; Mevalonic Acid; Models, Chemical; Open Reading Frames; Organophosphorus Compounds; Sequence Analysis, DNA; Streptomyces	2000
Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. Planta, 2002, Volume: 215, Issue:2 Topics: Aldose-Ketose Isomerases; Arabidopsis; Carotenoids; Chlorophyll; Chlorophyll A; Chloroplasts; Cloning, Molecular; Diterpenes; Diterpenes, Kaurane; DNA, Antisense; Fosfomycin; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Multienzyme Complexes; Nucleotidyltransferases; Organophosphorus Compounds; Oxidoreductases; Phenotype; Pigments, Biological; Plants, Genetically Modified	2002
Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. Journal of bacteriology, 2002, Volume: 184, Issue:18 Topics: Carbon Radioisotopes; Carbon-Carbon Double Bond Isomerases; Culture Media; Cyanobacteria; Fosfomycin; Hemiterpenes; Organophosphorus Compounds; Pentose Phosphate Pathway; Pentosephosphates; Photosynthesis; Pyruvic Acid	2002
Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America, 2003, May-27, Volume: 100, Issue:11 Topics: Arabidopsis; Base Sequence; Carotenoids; Chlorophyll; Cytosol; DNA Primers; Fosfomycin; Gene Expression Regulation, Plant; Hemiterpenes; Lovastatin; Organophosphorus Compounds; Plastids; Sterols	2003
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. The Journal of biological chemistry, 2007, Jul-06, Volume: 282, Issue:27 Topics: Aldose-Ketose Isomerases; Amino Acid Substitution; Animals; Bacterial Proteins; Binding Sites; Eukaryota; Fosfomycin; Hemiterpenes; Humans; Ligands; Manganese; Mevalonic Acid; Models, Molecular; Multienzyme Complexes; Mutation, Missense; Mycobacterium tuberculosis; NADP; Organophosphorus Compounds; Oxidation-Reduction; Oxidoreductases; Protein Structure, Quaternary; Terpenes; Xylulose	2007
Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum. PLoS biology, 2011, Volume: 9, Issue:8 Topics: Animals; Anti-Bacterial Agents; Cell Death; Chloroplasts; Fosfomycin; Genome, Protozoan; Hemiterpenes; Humans; Life Cycle Stages; Malaria; Models, Biological; Organophosphorus Compounds; Parasites; Plasmodium falciparum; Protein Transport; Protozoan Proteins; Terpenes	2011
Evidence of isoprenoid precursor toxicity in Bacillus subtilis. Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:12 Topics: Bacillus subtilis; Butadienes; Carbon-Carbon Double Bond Isomerases; Cell Proliferation; Cytotoxins; Erythritol; Fosfomycin; Genetic Engineering; Hemiterpenes; Organophosphorus Compounds; Pentanes; Sequence Deletion; Sugar Phosphates; Terpenes	2011
Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2 Topics: Antimalarials; Apicoplasts; Carbolines; Drug Discovery; Erythrocytes; Fosfomycin; Hemiterpenes; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Life Cycle Stages; Oligopeptides; Organophosphorus Compounds; Pipecolic Acids; Plasmodium falciparum; Small Molecule Libraries	2014
Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. PloS one, 2014, Volume: 9, Issue:4 Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Fosfomycin; Gene Expression Regulation, Bacterial; Hemiterpenes; Humans; Hydrogen Peroxide; Kanamycin; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Organophosphorus Compounds; Oxidative Stress; Salmonella typhimurium; Time Factors	2014
A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites. PLoS pathogens, 2020, Volume: 16, Issue:2 Topics: Animals; Anti-Bacterial Agents; Apicoplasts; Azithromycin; Fosfomycin; Hemiterpenes; Humans; Malaria; Mevalonic Acid; Organophosphorus Compounds; Parasites; Plasmodium falciparum; Plastids; Protozoan Proteins	2020