isoniazid has been researched along with trimethoprim in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 16 (40.00) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Arkile, MA; Degani, MS; Jadhav, NJ; Khambete, MP; Lele, AC; Rajan, MG; Raju, A; Ray, MK; Sarkar, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Anjum, MN; Arfan, M; Ayaz, M; Batool Kazmi, ST; Farooq, S; Haq, IU; Iftikhar, F; Rashid, U; Ullah, A | 1 |
| Bera, S; Mondal, D | 1 |
| Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K | 1 |
| Magnus, L; Sauerbrei, HU | 1 |
| Stingl, P | 1 |
| Dietz, M; Haas, M; Lindner, B; Seydel, U; Tebebe, YB | 1 |
| Koike, T; Kurasawa, K; Matsumura, R; Ohshima, H; Sugiyama, T; Takabayashi, K; Tomioka, H; Yamazaki, S; Yoshida, H; Yoshida, S | 1 |
| Freerksen, E; Rosenfeld, M; Spannuth, G | 1 |
| Endreffy, E; Megyeri, P | 1 |
| Gikalov, I; Hoigné, R; Keller, M; Klein, U | 1 |
| Freerksen, E; Rosenfeld, M | 2 |
| Blenska, W; Kolakowska, E | 1 |
| Berman, JD; Lee, LS | 1 |
| McConville, JH | 1 |
| De Cock, KM; Holmes, KK; Hu, DJ; Jaffe, HW; Kaplan, JE; Masur, H | 1 |
| Hoffman, G; Jolly, M; Molta, C | 1 |
| Chavarot, P; Dosso, M; Marchal, G; N'guessan, K; Pescher, P; Romain, F | 1 |
| Jacobs, WR; Vilchèze, C | 1 |
| Baker, B; Cotton, MF; Diacon, AH; Harper, C; Hesseling, A; Macingwana, L; Ngwane, AH; van Helden, P; Wiid, I | 1 |
| Jeon, KW | 1 |
3 review(s) available for isoniazid and trimethoprim
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Preventing opportunistic infections in human immunodeficiency virus-infected persons: implications for the developing world.
Topics: Africa; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Asia; Bacterial Vaccines; Caribbean Region; Developing Countries; Drug Therapy, Combination; Humans; Isoniazid; Latin America; Pneumococcal Vaccines; Research; Sulfamethoxazole; Trimethoprim | 1996 |
37 other study(ies) available for isoniazid and trimethoprim
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design and Synthesis of a Focused Library of Diamino Triazines as Potential Mycobacterium tuberculosis DHFR Inhibitors.
Topics: | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Amino acid conjugated antimicrobial drugs: Synthesis, lipophilicity- activity relationship, antibacterial and urease inhibition activity.
Topics: Amino Acids; Anti-Bacterial Agents; Bacillus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Hydrophobic and Hydrophilic Interactions; Isoniazid; Metronidazole; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Salmonella typhi; Staphylococcus aureus; Structure-Activity Relationship; Trimethoprim; Urease | 2018 |
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry | 2020 |
[Two cases of infantile cortical hyperostosis (monostotic form) (author's transl)].
Topics: Clavicle; Drug Therapy, Combination; Humans; Hyperostosis, Cortical, Congenital; Infant; Isoniazid; Male; Prednisone; Radiography; Respiratory Tract Infections; Sulfamethoxazole; Trimethoprim | 1978 |
[Leprosy in Africa. Current status and epidemiological significance].
Topics: Adolescent; Adult; Africa; Child; Cross-Sectional Studies; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Leprosy, Lepromatous; Leprosy, Tuberculoid; Prothionamide; Rifampin; Trimethoprim | 1992 |
Determination of in vivo and in vitro drug effects of mycobacteria from the mass spectrometric analysis of single organisms.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy, Borderline; Leprosy, Lepromatous; Mass Spectrometry; Mycobacterium; Mycobacterium leprae; Polymyxin B; Potassium; Rifampin; Sodium; Trimethoprim | 1991 |
[Pulmonary opportunistic infections in patients with autoimmune diseases].
Topics: Adult; Aged; Autoimmune Diseases; Female; Humans; Isoniazid; Lung Diseases, Fungal; Male; Middle Aged; Mycoses; Opportunistic Infections; Pneumonia, Pneumocystis; Prednisolone; Sulfamethoxazole; Trimethoprim; Tuberculosis, Pulmonary | 1989 |
New forms of multidrug therapy for the treatment of leprosy. First report for the practice on rifampicin + sulfamethoxazole-trimethoprim + protionamide and rifampicin + sulfamethoxazole-trimethoprim + isoniazid.
Topics: Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Prothionamide; Sulfamethoxazole; Trimethoprim | 1989 |
Improvement of defective bactericidal capacity of polymorphonuclear leukocytes by isoniazide in a case of chronic granulomatous disease.
Topics: Blood Bactericidal Activity; Drug Combinations; Granulomatous Disease, Chronic; Humans; Infant; Isoniazid; Male; Neutrophils; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1986 |
[Drug monitoring in the medical ward of a regional hospital].
Topics: Adult; Ampicillin; Anticoagulants; Antidepressive Agents; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Digitalis Glycosides; Drug Eruptions; Drug Hypersensitivity; Drug Synergism; Female; Humans; Hypnotics and Sedatives; Isoniazid; Male; Middle Aged; Monitoring, Physiologic; Penicillins; Rifamycins; Sulfamethoxazole; Time Factors; Tranquilizing Agents; Trimethoprim | 1972 |
Fundamental data, methods and goals of present research on the treatment of leprosy.
Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In Vitro Techniques; Isoniazid; Leprosy; Mice; Mycobacterium lepraemurium; Rifampin; Sulfonamides; Trimethoprim | 1973 |
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; Isoniazid; Leprosy; Mice; Models, Biological; Mycobacterium Infections; Phenazines; Pyrazines; Rabbits; Rifampin; Sulfonamides; Trimethoprim | 1972 |
A pilot study of leprosy treatment with a combination of various antileprosy drugs. Preliminary report.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Male; Pilot Projects; Pyrazines; Rifampin; Sulfanilamides; Sulfonamides; Time Factors; Trimethoprim; Uganda | 1973 |
Activity of oral drugs against Leishmania tropica in human macrophages in vitro.
Topics: Antiprotozoal Agents; Cells, Cultured; Drug Interactions; Humans; Isoniazid; Ketoconazole; Leishmania; Macrophages; Metronidazole; Nitrofurans; Phenothiazines; Quinacrine; Rifampin; Sulfamethoxazole; Trimethoprim | 1983 |
Whither the roles of rifater and rifamate?
Topics: Antitubercular Agents; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Trimethoprim; Tuberculosis | 1996 |
Wegener's granulomatosis: pitfalls in the management of pulmonary disease: A case of Wegener's granulomatosis with a hilar mass.
Topics: Adult; Cyclophosphamide; Drug Therapy, Combination; Ethambutol; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Isoniazid; Lymph Nodes; Male; Prednisone; Pyridoxine; Radiography, Thoracic; Sulfamethoxazole; Tomography, X-Ray Computed; Trimethoprim; Tuberculosis, Lymph Node | 2000 |
[Preliminary study on isoniazid-epiroprim combination in a tuberculosis murine model].
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Isoniazid; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Trimethoprim; Tuberculosis, Pulmonary | 2002 |
The combination of sulfamethoxazole, trimethoprim, and isoniazid or rifampin is bactericidal and prevents the emergence of drug resistance in Mycobacterium tuberculosis.
Topics: Anaerobiosis; Anti-Bacterial Agents; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Sulfamethoxazole; Trimethoprim; Tuberculosis, Multidrug-Resistant | 2012 |
Sulfamethoxazole enhances the antimycobacterial activity of rifampicin.
Topics: Antitubercular Agents; Drug Synergism; Ethambutol; Isoniazid; Mycobacterium tuberculosis; Rifampin; Sulfamethoxazole; Trimethoprim | 2012 |
A new method for obtaining aposymbiotic hydra using trimethoprim as a bleaching agent.
Topics: Eukaryota; Hydra; Symbiosis; Trimethoprim | 1977 |