isoniazid has been researched along with thioridazine in 25 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (4.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (20.00) | 29.6817 |
2010's | 18 (72.00) | 24.3611 |
2020's | 1 (4.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Alam, MZ; Bruhn, DF; Feng, L; Hurdle, JG; Lee, RB; Lee, RE; Maddox, MM; Narula, G; Sandhaus, S; Simmons, CJ; Sun, D; Tse-Dinh, YC; Tsutsumi, LS; Wu, X | 1 |
Dixit, PP; Thore, SN | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bhakta, S; Brown, AK; Castagnolo, D; Maitra, A; Manetti, F; Pavan, FR; Petricci, E; Ribeiro, CM; Scalacci, N; Smith, DL | 1 |
Azzali, E; Cabassi, CS; Costantino, G; Flisi, S; Kaushik, A; Lamichhane, G; Machado, D; Pieroni, M; Vacondio, F; Viveiros, M | 1 |
Aziz, DB; Dick, T; Go, ML; Gopal, P; Li, M; Nyantakyi, SA | 1 |
Dalimba, U; Madan Kumar, S; Reddyrajula, R | 1 |
Barreca, ML; Bojarski, AJ; Cecchetti, V; Cook, GM; Desantis, J; Felicetti, T; Franzblau, SG; Handzlik, J; Hards, K; Kolář, MH; Latacz, G; Manfroni, G; Massari, S; Mazzarella, MA; Nakatani, Y; Nizi, MG; Rushton-Green, R; Sabatini, S; Satała, G; Shetye, G; Tabarrini, O | 1 |
Wasik, A | 1 |
To, TQ; Townsend, JC | 1 |
Amaral, L; Baptista, P; Couto, I; Machado, D; Perdigão, J; Portugal, I; Rodrigues, L; Veigas, B; Viveiros, M | 1 |
Gumbo, T; Leff, R; Meek, C; Musuka, S; Pasipanodya, J; Siyambalapitiyage Dona, CW; Srivastava, S | 1 |
Dutta, NK; Karakousis, PC; Pinn, ML | 2 |
Dutta, NK; Karakousis, PC | 1 |
Sharma, S; Singh, A | 1 |
Aarnoutse, R; Bakker-Woudenberg, IA; Boeree, MJ; de Knegt, GJ; de Steenwinkel, JE; ten Kate, MT; van Soolingen, D | 1 |
Gold, B; Jacobs, WR; Jiang, X; Kaminski, L; Mi, J; Nathan, CF; Park, S; Roberts, J; Saito, K; Shigyo, K; Somersan-Karakaya, S; Warrier, T; Weber, E | 1 |
1 review(s) available for isoniazid and thioridazine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
24 other study(ies) available for isoniazid and thioridazine
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
Topics: Animals; Anti-Bacterial Agents; Chalcones; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Chromones; DNA Gyrase; DNA Topoisomerase IV; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phloroglucinol; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells | 2014 |
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis.
Topics: Antitubercular Agents; Cells, Cultured; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Triazoles | 2016 |
Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis.
Topics: Antitubercular Agents; Cell Line; Chemistry Techniques, Synthetic; Drug Design; Drug Resistance, Multiple; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Thioridazine | 2017 |
Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Drug Resistance, Multiple, Bacterial; Drug Stability; Ethidium; Humans; Isoxazoles; Macrophages; Membrane Transport Proteins; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Thiazoles; Thioridazine; Verapamil | 2017 |
Indolylalkyltriphenylphosphonium Analogues Are Membrane-Depolarizing Mycobactericidal Agents.
Topics: | 2017 |
Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Phenothiazines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Triazoles; Vero Cells | 2019 |
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Synergism; Enzyme Inhibitors; HEK293 Cells; Humans; Microsomes, Liver; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADH Dehydrogenase; Organoselenium Compounds; Parasitic Sensitivity Tests; Phenothiazines; Protein Binding; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Vero Cells | 2020 |
Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.
Topics: Affective Symptoms; Age Factors; Alcoholism; Central Nervous System Diseases; Delirium; Delusions; Epilepsy; Female; Humans; Isoniazid; Male; Nervous System Diseases; Neurotic Disorders; Personality Disorders; Polyneuropathies; Promazine; Psychoses, Substance-Induced; Sympathetic Nervous System; Thioridazine; Tuberculosis, Pulmonary | 1970 |
Ocular toxicity of systemic medications: a case series.
Topics: Adult; Aged; Amiodarone; Cataract; Corneal Diseases; Eye Diseases; Female; Glaucoma; Humans; Isoniazid; Male; Middle Aged; Optic Neuritis; Prednisone; Retinal Diseases; Thioridazine; Vision Disorders; Visual Acuity; Visual Fields | 2000 |
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase; Chlorpromazine; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Gene Expression; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Rifampin; Thioridazine; Tuberculosis, Multidrug-Resistant; Verapamil | 2012 |
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners.
Topics: Antipsychotic Agents; Antitubercular Agents; Colony Count, Microbial; Computer Simulation; Drug Administration Schedule; Drug Design; Drug Repositioning; Drug Resistance, Bacterial; Humans; Infusions, Intravenous; Isoniazid; Latent Tuberculosis; Microbial Sensitivity Tests; Models, Statistical; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Time Factors | 2013 |
Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.
Topics: Animals; Antipsychotic Agents; Antitubercular Agents; Disease Models, Animal; Drug Repositioning; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Isoniazid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Thioridazine; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Tuberculosis, Pulmonary | 2014 |
Thioridazine for treatment of tuberculosis: promises and pitfalls.
Topics: Animals; Antitubercular Agents; Female; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Tuberculosis | 2014 |
Chemotherapeutic efficacy of thioridazine as an adjunct drug in a murine model of latent tuberculosis.
Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Isoniazid; Latent Tuberculosis; Male; Mice; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Rifampin; Thioridazine | 2014 |
Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Isoniazid; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Stem Cells; Thioridazine; Tuberculosis | 2014 |
Rifamycin action on RNA polymerase in antibiotic-tolerant
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Rifamycins; Thioridazine; Tuberculosis | 2017 |