isoniazid and thiophenes

isoniazid has been researched along with thiophenes in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mitchell, JR; Potter, WZ1
Dybing, E; McMurtry, RJ; Mitchell, JR; Nelson, SD; Thorgeirsson, SS1
Collins, T; Levett, PN1
Ilampurnam, KJ; Paramasivan, CN; Prabhakar, R; Venkataraman, P1
Gross, WM; Hawkins, JE1
Nüesch, E; Ohnhaus, EE1
Doubek, JR; Wayne, LG1
Dernuet, S; Mankiewicz, E1
Collins, CH; Grange, JM; Yates, MD1
Barry, CE; Lee, RE; Slayden, RA1
Barry, CE; Slayden, RA1
Betts, JC; Blakemore, SJ; Duncan, K; Kelly, FM; Lennon, MG; Lukey, PT; McLaren, A1
FEDI, M1
Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ1
Cicek, E; Delibas, N; Gokalp, O; Ozcelik, N; Ozer, MK; Sutcu, R; Uz, E; Yilmaz, HR1
Ciçek, E; Gökalp, O; Ozçelik, N; Ozer, MK; Uz, E; Yilmaz, HR1
Azeeza, S; Kamal, A; Malik, MS; Rao, MV; Shaik, AA1
Ahmad, I; Barnes, SW; Batt, SM; Besra, GS; Chatterjee, AK; Franzblau, S; Fütterer, K; Halder, R; Hassani, M; Huszar, S; Jacobs, WR; Johnson, K; Johnsson, K; Kaneko, T; Kim, J; Ma, Z; Mdluli, KE; Mikusova, K; Robbins, SH; Sambandan, D; Schultz, PG; Trefzer, C; Walker, JR; Wang, F; Wang, J; Weinrick, B; Yang, P; Zhang, Y1

Reviews

3 review(s) available for isoniazid and thiophenes

ArticleYear
Drug metabolism in the production of liver injury.
    The Medical clinics of North America, 1975, Volume: 59, Issue:4

    Topics: Acetaminophen; Acetanilides; Alkylating Agents; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Drug Hypersensitivity; Ethers; Furosemide; Glutathione; Halothane; Humans; Inactivation, Metabolic; Isoniazid; Liver; Liver Neoplasms; Necrosis; Pharmaceutical Preparations; Phenacetin; Protein Binding; Thiophenes

1975
Metabolic activation: biochemical basis for many drug-induced liver injuries.
    Progress in liver diseases, 1976, Volume: 5

    Topics: Acetaminophen; Animals; Binding Sites; Carcinogens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hydrazines; Isoniazid; Liver; Methyldopa; Necrosis; Pharmaceutical Preparations; Phenacetin; Thiophenes

1976
Efforts towards the development of new antitubercular agents: potential for thiolactomycin based compounds.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Sep-09, Volume: 11, Issue:2

    Topics: Animals; Antitubercular Agents; Drug Design; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Physiological Phenomena; Pyrazinamide; Rifamycins; Streptomycin; Thiophenes; Tuberculosis; Tuberculosis, Pulmonary

2008

Other Studies

15 other study(ies) available for isoniazid and thiophenes

ArticleYear
Radiometric studies on the use of selective inhibitors in the identification of Mycobacterium spp.
    Journal of medical microbiology, 1989, Volume: 30, Issue:3

    Topics: Drug Resistance, Microbial; Humans; Hydroxypropiophenone; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Mycobacterium bovis; Mycobacterium tuberculosis; Nitrobenzoates; Nontuberculous Mycobacteria; Radiometry; Species Specificity; Thiophenes

1989
Intraspecies differentiation of strains of Mycobacterium tuberculosis obtained from Czechoslovakian, Mongolian and south Indian patients.
    The Indian journal of medical research, 1988, Volume: 88

    Topics: Animals; Czechoslovakia; Guinea Pigs; India; Isoniazid; Microbial Sensitivity Tests; Mongolia; Mycobacterium tuberculosis; Thiophenes; Virulence

1988
Radiometric selective inhibition tests for differentiation of Mycobacterium tuberculosis, Mycobacterium bovis, and other mycobacteria.
    Journal of clinical microbiology, 1985, Volume: 21, Issue:4

    Topics: Hydroxylamine; Hydroxylamines; Isoniazid; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Thiophenes

1985
Lack of effect of the appetite stimulant pizotifen (BC 105) on the absorption of isonicotinylhydrazine.
    European journal of clinical pharmacology, 1974, Volume: 7, Issue:1

    Topics: Adult; Benzocycloheptenes; Half-Life; Humans; Intestinal Absorption; Isoniazid; Male; Middle Aged; Piperidines; Regression Analysis; Thiophenes; Time Factors

1974
Diagnostic key to mycobacteria encountered in clinical laboratories.
    Applied microbiology, 1968, Volume: 16, Issue:6

    Topics: Bacteriological Techniques; Catalase; Drug Resistance, Microbial; Humans; Iron; Isoniazid; Mycobacterium; Nicotinic Acids; Nitrates; Oxidation-Reduction; Pigments, Biological; Sulfatases; Surface-Active Agents; Thiophenes

1968
Bacteriophage typing and chemical and biologic tests in the classification of mycobacteria. A comparative study.
    The American review of respiratory disease, 1968, Volume: 98, Issue:1

    Topics: Amidohydrolases; Animals; Bacteriophage Typing; Catalase; Culture Media; Drug Resistance, Microbial; Guinea Pigs; Isoniazid; Mycobacteriophages; Mycobacterium; Nicotinic Acids; Nitrates; Peroxidases; Pigmentation; Rabbits; Streptomycin; Sulfatases; Thiophenes

1968
A study of the relationship between the resistance of Mycobacterium tuberculosis to isonicotinic acid hydrazide (isoniazid) and to thiophen-2-carboxylic acid hydrazide.
    Tubercle, 1984, Volume: 65, Issue:4

    Topics: Asian People; Drug Resistance, Microbial; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Thiophenes; White People

1984
Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.
    Molecular microbiology, 2000, Volume: 38, Issue:3

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyltransferases; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Microbial; Enzyme Inhibitors; Fatty Acid Synthase, Type II; Humans; Isoniazid; Lipids; Microbial Sensitivity Tests; Multienzyme Complexes; Mycobacterium smegmatis; Mycobacterium tuberculosis; Operon; Oxidoreductases; Thiophenes; Triclosan

2000
The role of KasA and KasB in the biosynthesis of meromycolic acids and isoniazid resistance in Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2002, Volume: 82, Issue:4-5

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Antibiotics, Antitubercular; Cell-Free System; Culture Media; Drug Resistance, Bacterial; Fatty Acid Synthases; Isoniazid; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Mycolic Acids; Substrate Specificity; Thiophenes; Triclosan

2002
Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antitubercular Agents; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Bacterial; Isoniazid; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Operon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; Thiophenes; Triclosan; Up-Regulation

2003
[Condensations of isonicotinic and cyanacetic hydrazides with some thienyl ketones. III].
    Bollettino chimico farmaceutico, 1961, Volume: 100

    Topics: Anti-Bacterial Agents; Hydrazines; Isoniazid; Ketones; Thiophenes

1961
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes

2005
The effects of isoniazid on hippocampal NMDA receptors: protective role of erdosteine.
    Molecular and cellular biochemistry, 2005, Volume: 277, Issue:1-2

    Topics: Animals; Antioxidants; Antitubercular Agents; Hippocampus; Isoniazid; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thioglycolates; Thiophenes

2005
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
    Toxicology and industrial health, 2008, Volume: 24, Issue:8

    Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase

2008
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-02, Volume: 110, Issue:27

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Antitubercular Agents; Bacterial Proteins; Benzothiazoles; Biofilms; Carbohydrate Epimerases; Drug Resistance, Bacterial; Female; Genes, Bacterial; High-Throughput Screening Assays; Isoniazid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium tuberculosis; Oxidoreductases; Rifampin; Thiophenes; Tuberculosis, Pulmonary

2013