Compounds > isoniazid

isoniazid and rotenone

isoniazid has been researched along with rotenone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Martinez-Medellin, J; Schulman, HM; Sidloi, R1
Cho, T; Uetrecht, J; Wang, X1
Cho, T; Uetrecht, J1
Fromenty, B1

Other Studies

8 other study(ies) available for isoniazid and rotenone

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The reticulocyte-mediated release of iron and bicarbonate from transferrin: effect of metabolic inhibitors.
    Biochimica et biophysica acta, 1974, May-24, Volume: 343, Issue:3

    Topics: Animals; Antimetabolites; Arsenic; Azides; Bicarbonates; Binding Sites; Carbon Radioisotopes; Cobalt; Cyanides; Cycloheximide; Dinitrophenols; Ethylmaleimide; Fluorides; Heme; Iodoacetates; Iron; Iron Radioisotopes; Isoniazid; Oligomycins; Protein Binding; Reticulocytes; Rotenone; Time Factors; Transferrin

1974
Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury.
    Chemical research in toxicology, 2019, 07-15, Volume: 32, Issue:7

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Female; Isoniazid; Liver; Mice, Inbred C57BL; Mitochondria; Rotenone

2019
Response to the Letter to the Editor Concerning the Article "Rotenone Increases Isoniazid Toxicity but Does Not Cause Liver Injury: Implications for the Hypothesis That Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idio
    Chemical research in toxicology, 2020, 01-21, Volume: 33, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Electron Transport; Humans; Isoniazid; Rotenone

2020
Letter to the Editor Regarding the Article Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncra
    Chemical research in toxicology, 2020, 01-21, Volume: 33, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Electron Transport; Humans; Isoniazid; Rotenone

2020