isoniazid and phenobarbital

isoniazid has been researched along with phenobarbital in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	60 (58.25)	18.7374
1990's	22 (21.36)	18.2507
2000's	15 (14.56)	29.6817
2010's	6 (5.83)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Valla, D	1
Javid, MJ; Stone, WE	1
Kutt, H	2
Costa, E; Guidotti, A; Mao, CC; Suria, A	1
Costa, E; Guidotti, A; Naik, SR	1
Sotaniemi, S	1
Balazs, T; Farber, TM; Feuer, G	1
Foglietti, MJ; Micheletti, C; Percheron, F	1
Timbrell, JA	1
Nasir, SM; Nasir, SS; Wilken, LO	1
Kupferberg, HJ; Sutton, G	1
Beubler, E; Lembeck, F	1
Solomonraj, G; Thomas, BH	1
Venho, VM	3
Gillette, JR; Mitchell, JR; Snodgrass, WR	1
Johnson, J	1
Grishanova, AIu; Kozlovskaia, NE; Liakhovich, VV; Mishin, VM	1
Awad, JA; Badr, KF; Burk, RF; Kato, T; Morrow, JD; Roberts, LJ; Takahashi, K	1
Hoffmann, P; Pankow, D; Weise, M	1
Blaauboer, BJ; de Kruif, CA; Falke, HE; Noordhoek, J; van Iersel, AA; Wortelboer, HM	1
Karthikeyan, S; Krishnamoorthy, MS	1
Gelboin, HV; Huang, Q; Ji, C; Mirvish, SS; Park, SS; Wang, S	1
Bui, QD; Weisz, J; Wrighton, SA	1
Burk, RF; Hill, KE; Hunt, RW; Martin, AE	1
Feely, M; Hardy, E; Kumar, S; Peaker, S; Pullar, T	1
Fry, JR; Hammond, AH	1
Dich, J; Grunnet, N; Vind, C	1
Gregus, Z; Klaassen, CD; Madhu, C	1
Baciewicz, AM	1
Brownstein, D; Parish, RA	1
Cmielewski, PL; Cousins, MJ; Hall, PD; Ilsley, AH; Jenner, MA; Plummer, JL	1
Burk, RF; Hill, KE; Lane, JM	1
Thomas, BH; Whitehouse, LW; Zeitz, W	1
Ardies, CM; Lasker, JM; Lieber, CS	1
Lauterburg, BH; Mitchell, JR; Smith, CV; Todd, EL	1
Goto, S; Hsu, KY; Noda, A; Noda, H; Ohno, K; Sendo, T	1
La Du, BN	1
Kutt, H; Penry, JK	1
Kar, PP; Matin, MA	2
Lequesne, M	1
Ganshorn, A; Kurz, H	1
Wiśniewski, K	1
Houillon, G; Houillon, P; Samulak, G	1
Saad, SF	1
Kutt, H; Verebely, K	1
el-Masry, AM; Saad, SF; Scott, PM	1
Eade, NR; Renton, KW	1
Breunig, HL; Broadlick, DE; Comer, JP; Sampson, CB	1
Phatak, AT; Shah, SH	1
Bruncsák, A; Timár, S	1
Burba, JV	1
Iwainsky, H; Wiezorek, WD	1
Airth, JM; Bray, DF; Radecka, C	1
Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A	1
Kudrin, AN; Makarov, VA	1
Gadeholt, G	1
Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA	1
Clemmesen, J; Hjalgrim-Jensen, S	1
Korzhov, VI; Maliuk, VI; Molotkov, VN	1
Bahri, AK; Chiang, CS; Timbrell, JA	2
Burke, TR; George, JW; Martin, JL; Pohl, LR	1
Demedts, M; Derveaux, L; Fevery, J; Gyselen, A	1
Jenner, AM; Timbrell, JA	1
Aniya, Y; Naito, A; Shimoji, M	1
Brouland, JP; Descotes, J; Patriarca, C; Verdier, F	1
Baker, MT; Chadam, MV; Ronnenberg, WC	1
Baker, MT; Ronnenberg, WC	1
Blaauboer, BJ; Luijckx, NB; Mennes, WC; Noordhoek, J; Wortelboer, HM	1
Horbach, GJ; Te Koppele, JM; Van Asten, JG	1
Awad, JA; Franks, JJ; Horn, JL; Roberts, LJ	1
Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM	1
Bergmann, K; Damme, B; Pankow, D; Wünscher, U	1
Amacher, DE; Schomaker, SJ	1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM	1
Evans, DC; Lake, BG; Meneses-Lorente, G; Price, RJ; Renwick, AB; Surry, D	1
Bu, S; Kim, S; Kim, Y; Lee, M	1
Hurh, E; Kim, S; Kim, Y; Lee, A; Lee, E; Lee, M	1
Finch, RA; Fort, DJ; Rogers, RL; Stover, EL	1
Finch, RA; Fort, DJ; Paul, RR; Rogers, RL; Stover, EL	1
Antonian, L; Burton, LA; Carroll, KM; Czerwinski, M; Downey, AD; Forster, J; Gan, LS; Graham, RA; Koch, P; Krueger, LA; LeCluyse, EL; Madan, A; Mudra, DR; Parkinson, A; Ribadeneira, MD; Robertson, P; Wagner, G; Yu, L; Zech, K	1
RAJTAR-LEONTIEW, Z; ZALEWSKI, T	1
HEINONEN, J	1
Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ	1
Catania, JR; McGarrigle, BP; Olson, JR; Rittenhouse-Olson, K	1
de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA	1

Reviews

8 review(s) available for isoniazid and phenobarbital

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New concepts on the mechanism of action of benzodiazepines. Life sciences, 1975, Jul-15, Volume: 17, Issue:2 Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra	1975
The role of metabolism in the hepatotoxicity of isoniazid and iproniazid. Drug metabolism reviews, 1979, Volume: 10, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cobalt; Humans; Hydrazines; Iproniazid; Isoniazid; Phenobarbital	1979
Carbamazepine drug interactions. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin	1986
Biochemical and genetic factors regulating dilantin metabolism in man. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines	1971
Pharmacogenetics: defective enzymes in relation to reactions to drugs. Annual review of medicine, 1972, Volume: 23 Topics: Acetylation; Cholinesterases; Coumarins; Dicumarol; Dose-Response Relationship, Drug; Female; Genetic Code; Genetic Diseases, Inborn; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Male; Metabolism, Inborn Errors; Pharmacogenetics; Phenacetin; Phenobarbital; Phenytoin; Succinylcholine	1972
Usefulness of blood levels of antiepileptic drugs. Archives of neurology, 1974, Volume: 31, Issue:5 Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines	1974
[Mechanism of absorption and acetylation of sulfanilamides in the body]. Klinicheskaia meditsina, 1983, Volume: 61, Issue:11 Topics: Acetyl Coenzyme A; Acetylation; Aminosalicylic Acid; Animals; Arylamine N-Acetyltransferase; Chymotrypsin; Gastric Juice; Humans; Intestinal Absorption; Intestine, Large; Intestine, Small; Isoniazid; Phenobarbital; Rats; Sodium Chloride; Sulfanilamides; Sulfates; Sulfathiazole; Sulfathiazoles	1983

Other Studies

95 other study(ies) available for isoniazid and phenobarbital

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
[Hepatic metabolism of foreign substances. Enzymatic hydroxylation system of hepatic microsomes and of cytochrome P-450]. Medecine & chirurgie digestives, 1978, Volume: 7, Issue:3 Topics: Anticoagulants; Benzopyrenes; Biotransformation; Cytochrome P-450 Enzyme System; Epoxy Compounds; Ethanol; Humans; Hydroxylation; Iproniazid; Isoniazid; Liver; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Phenobarbital	1978
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants. Epilepsia, 1978, Volume: 19, Issue:4 Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency	1978
Interactions of antiepileptic drugs. Epilepsia, 1975, Volume: 16, Issue:2 Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines	1975
Central GABA receptor agonists: comparison of muscimol and baclofen. Neuropharmacology, 1976, Volume: 15, Issue:8 Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P	1976
Effect of diphenylhydantoin on the apposition of dentin. An experimental study in the rat. Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1977, Volume: 73, Issue:4-6 Suppl Topics: Alkaline Phosphatase; Animals; Body Weight; Calcium; Cholecalciferol; Connective Tissue; Dentinogenesis; Female; Isoniazid; Liver; Male; Microsomes, Liver; Odontogenesis; Organ Size; Phenobarbital; Phenytoin; Phosphates; Rats; Sex Factors	1977
Drug-induced changes in serum alkaline phosphatase and alanine aminotransferase activities not related to hepatic injuries. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1978, Issue:1 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Cefazolin; Dogs; Enzyme Induction; Female; Isoniazid; Male; Phenobarbital; Rats	1978
[Enzymatic induction during isoniazid therapy (author's transl)]. Pathologie-biologie, 1979, Volume: 27, Issue:8 Topics: Acetylation; Enzyme Induction; Glucaric Acid; Humans; Isoniazid; Oxidoreductases; Phenobarbital; Phenotype	1979
New in vitro dissolution test apparatus. Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:2 Topics: Aspirin; Chemistry, Pharmaceutical; Isoniazid; Phenobarbital; Piperazines; Solubility; Sulfadiazine; Tablets	1979
Isoniazid as an inhibitor of primidone metabolism. Neurology, 1975, Volume: 25, Issue:12 Topics: Depression, Chemical; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Isoniazid; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Pyridoxine; Tuberculosis, Miliary	1975
Convulsions induced by hyperbaric oxygen: inhibition by phenobarbital, diazepam and baclofen. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1 Topics: Aminobutyrates; Animals; Baclofen; Diazepam; Female; gamma-Aminobutyric Acid; Glycine; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Phenobarbital; Rats; Seizures; Strychnine	1977
Drug interactions with isoniazid metabolism in rats. Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:9 Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspirin; Drug Interactions; Ethambutol; Ethanol; Injections, Intravenous; Isoniazid; Male; Phenobarbital; Rats; Rifampin; Time Factors; Tissue Distribution	1977
Effect of methotrexate on drug absorption from the rat small intestine in situ and in vitro. Acta pharmacologica et toxicologica, 1976, Volume: 38, Issue:5 Topics: Animals; Female; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Isoniazid; Mecamylamine; Methotrexate; Phenobarbital; Quinidine; Rats; Sulfisoxazole; Time Factors	1976
Drug absorption from the small intestine of the triparanol-treated rat in situ. Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:3 Topics: Animals; Female; Injections, Intravenous; Intestinal Absorption; Intestine, Small; Isoniazid; Mecamylamine; Phenobarbital; Quinidine; Rats; Sulfisoxazole; Triparanol	1976
The role of biotransformation in chemical-induced liver injury. Environmental health perspectives, 1976, Volume: 15 Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cricetinae; Furosemide; Glutathione; Guinea Pigs; Humans; In Vitro Techniques; Iproniazid; Isoniazid; Liver Diseases; Methylcholanthrene; Mice; Phenobarbital; Rats	1976
Drug absorption from the irradiated rat small intestine in situ. Arzneimittel-Forschung, 1976, Volume: 26, Issue:10 Topics: Animals; Female; Gamma Rays; Intestinal Absorption; Intestine, Small; Isoniazid; Kinetics; Mecamylamine; Phenobarbital; Quinidine; Rats; Sulfisoxazole; Time Factors	1976
Letter: Epanutin and isoniazid interaction. British medical journal, 1975, Jan-18, Volume: 1, Issue:5950 Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin	1975
[The effect of tetrahydrofuran on the microsomal monooxygenase system in vitro and in vivo]. Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:12 Topics: Acetone; Animals; Enzyme Induction; Furans; Isoniazid; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Wistar	1992
Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. The Journal of clinical investigation, 1992, Volume: 90, Issue:6 Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Indomethacin; Isoniazid; Lipid Peroxides; Male; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Thioacetamide	1992
Effect of isoniazid or phenobarbital pretreatment on the metabolism of dihalomethanes to carbon monoxide. Polish journal of occupational medicine and environmental health, 1992, Volume: 5, Issue:3 Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Hydrocarbons, Brominated; Hydrocarbons, Halogenated; Isoniazid; Male; Methylene Chloride; Phenobarbital; Rats; Rats, Wistar	1992
Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2 Topics: Animals; Apoproteins; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Blotting, Western; Cells, Cultured; Clofibrate; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dexamethasone; Enzyme Induction; Isoenzymes; Isoniazid; Liver; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases	1991
Effect of phenobarbitone pretreatment on isoniazid-induced lipid changes in plasma, liver and adipose tissue in the rabbit. Pharmacological research, 1991, Volume: 24, Issue:3 Topics: Adipose Tissue; Analysis of Variance; Animals; Cholesterol; Drug Interactions; Fatty Acids; Female; Isoniazid; Lipid Metabolism; Lipids; Liver; Male; Phenobarbital; Rabbits; Triglycerides	1991
Positional specificity for methyl-n-amylnitrosamine hydroxylation by cytochrome P-450 isozymes determined with monoclonal antibodies. Cancer research, 1991, Feb-15, Volume: 51, Issue:4 Topics: Animals; Antibodies, Monoclonal; Aroclors; Carcinogens; Cytochrome P-450 Enzyme System; Hydroxylation; Isoenzymes; Isoniazid; Liver; Male; Methylcholanthrene; Microsomes; Nitrosamines; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Sex Factors; Substrate Specificity	1991
Hepatic catecholestrogen synthases: differential effect of sex, inducers of cytochromes P-450 and of antibody to the glucocorticoid inducible cytochrome P-450 on NADPH-dependent estrogen-2-hydroxylase and on organic hydroperoxide-dependent estrogen-2/4-hy The Journal of steroid biochemistry and molecular biology, 1990, Volume: 37, Issue:2 Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Estradiol; Estrogens, Catechol; Female; Isoniazid; Kinetics; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors	1990
Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it. Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Fomepizole; Glutathione; Isoniazid; Liver; Male; Phenobarbital; Pyrazoles; Rats; Rats, Inbred F344	1990
A comparison of a short half-life marker (low-dose isoniazid), a long half-life pharmacological indicator (low-dose phenobarbitone) and measurements of a controlled release 'therapeutic drug' (metoprolol, Metoros) in reflecting incomplete compliance by vo British journal of clinical pharmacology, 1990, Volume: 30, Issue:3 Topics: Administration, Oral; Adult; Delayed-Action Preparations; Female; Half-Life; Humans; Isoniazid; Male; Metoprolol; Phenobarbital	1990
The in vivo induction of rat hepatic cytochrome P450-dependent enzyme activities and their maintenance in culture. Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Isoniazid; Liver; Male; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains	1990
Effects of cytochrome P450-inducing agents on the monooxygenation of testosterone in long-term cultures of hepatocytes from male and female rats. Archives of biochemistry and biophysics, 1989, Nov-15, Volume: 275, Issue:1 Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Glucagon; Hydroxylation; Insulin; Isoniazid; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Species Specificity; Steroid 16-alpha-Hydroxylase; Testosterone	1989
Inducibility of glutathione S-transferases in hamsters. Cancer letters, 1989, Volume: 44, Issue:2 Topics: Animals; Butylated Hydroxyanisole; Cats; Cricetinae; Dexamethasone; Dogs; Enzyme Induction; Ethanol; Glutathione Transferase; Guinea Pigs; Isoniazid; Liver; Male; Mesocricetus; Methylcholanthrene; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Quail; Rabbits; Rats; Species Specificity; Stilbenes; Trout	1989
Emergency department management of children with acute isoniazid poisoning. Pediatric emergency care, 1986, Volume: 2, Issue:2 Topics: Adolescent; Child; Diazepam; Emergencies; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Isoniazid; Male; Phenobarbital; Suicide, Attempted	1986
Effects of treatment with phenobarbitone or isoniazid on hepatotoxicity due to prolonged subanaesthetic halothane inhalation. Pharmacology & toxicology, 1988, Volume: 62, Issue:2 Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Halothane; Isoniazid; Liver; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Time Factors	1988
Inhibition of CCl4 metabolism by oxygen varies between isoenzymes of cytochrome P-450. Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3 Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Isoenzymes; Isoniazid; Male; Microsomes, Liver; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains	1988
Effect of rifampin, phenobarbital pretreatment, and acetylator phenotype on acetylisoniazid metabolism in the rabbit. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:3 Topics: Acetylation; Animals; Isoniazid; Kinetics; Liver; Male; Phenobarbital; Phenotype; Protein Binding; Rabbits; Rifampin; Tissue Distribution	1987
Characterization of the cytochrome P-450 monooxygenase system of hamster liver microsomes. Effects of prior treatment with ethanol and other xenobiotics. Biochemical pharmacology, 1987, Nov-01, Volume: 36, Issue:21 Topics: Animals; Benzoflavones; Benzphetamine; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Ethanol; Isoniazid; Male; Mesocricetus; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Oxygenases; Phenobarbital; Species Specificity	1987
Oxidation of hydrazine metabolites formed from isoniazid. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:5 Topics: Acetylation; Adult; Carbon Dioxide; Carbon Radioisotopes; Female; Humans; Hydrazines; Isoniazid; Liver; Male; Oxidation-Reduction; Phenobarbital	1985
Effects of rifampicin and phenobarbital on the fate of isoniazid and hydrazine in vivo in rats. Toxicology letters, 1985, Volume: 25, Issue:3 Topics: Acetylation; Animals; Drug Interactions; Hydrazines; Isoniazid; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Rifampin	1985
Possible role of gamma-aminobutyric acid in paraoxon-induced convulsions. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:12 Topics: Aminobutyrates; Animals; Brain Chemistry; Insecticides; Isoniazid; Male; Paraoxon; Phenobarbital; Rats; Seizures	1972
Psychiatric side effects of nonpsychiatric drugs. Seminars in psychiatry, 1971, Volume: 3, Issue:4 Topics: Aminophylline; Analgesics; Anti-Anxiety Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; Antihypertensive Agents; Central Nervous System Stimulants; Chlordiazepoxide; Diazepam; Diuretics; Drug-Related Side Effects and Adverse Reactions; Furosemide; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Insulin; Isoniazid; Mental Disorders; Methyldopa; Phenobarbital; Prednisone	1971
Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice. Pharmacological research communications, 1974, Volume: 6, Issue:4 Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Brain Chemistry; DDT; Drug Synergism; gamma-Aminobutyric Acid; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures	1974
[Algodystrophy of chemotherapeutic origin. Pseudorheumatism due to isoniazid, ethionamide, phenobarbital and radioactive iodine]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1967, Oct-14, Volume: 43, Issue:42 Topics: Adult; Aged; Ethionamide; Female; Humans; Iodine Isotopes; Isoniazid; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystrophy; Tuberculosis	1967
[Differences between the protein binding of newborns and adults and their importance for pharmacological action]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental	1968
[The studies on "nonspecific transport effect" of insulin]. Roczniki Akademii Medycznej im. Juliana Marchlewskiego w Bialymstoku. Suplement, 1968, Volume: 20 Topics: Adenosine Triphosphatases; Animals; Biological Transport; Brain Chemistry; Cell Membrane Permeability; Chlorpromazine; Diabetes Mellitus, Experimental; Drug Synergism; Hydroxyzine; Insulin; Isoniazid; Phenobarbital; Rats; Reserpine	1968
[Apropos of a case of Gayet-Wernicke's encephalopathy in a latent epileptic. Centrophenoxine and thiamine. Electro-clinical contraindications]. Annales medico-psychologiques, 1968, Volume: 1, Issue:1 Topics: Acetates; Adult; Central Nervous System Stimulants; Epilepsy, Tonic-Clonic; Humans; Hydroxocobalamin; Injections, Intravenous; Isoniazid; Male; Meclofenoxate; Phenobarbital; Pyridoxine; Substance Withdrawal Syndrome; Thiamine; Tuberculosis, Pulmonary; Vitamin B Deficiency; Wernicke Encephalopathy	1968
The effect of isoniazid and some anticonvulsant drugs on the gamma-aminobutyric acid content of mouse brain in insulin hypoglycaemia. The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5 Topics: Aminobutyrates; Animals; Barbiturates; Brain; Brain Chemistry; Cerebral Cortex; Hypoglycemia; Insulin Antagonists; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures	1970
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction. Biochemical pharmacology, 1970, Volume: 19, Issue:3 Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature	1970
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice. European journal of pharmacology, 1972, Volume: 17, Issue:3 Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical	1972
Microsomal enzymes and potentiation of tyramine pressor response. Biochemical pharmacology, 1972, May-15, Volume: 21, Issue:10 Topics: Animals; Blood Pressure; Drug Synergism; Enzyme Induction; In Vitro Techniques; Isoniazid; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Phenelzine; Phenobarbital; Proadifen; Rats; Subcellular Fractions; Time Factors; Tyramine	1972
Estimation of mean potency and content uniformity of tablets: a new approach. Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:2 Topics: Atropine; Caffeine; Chemistry, Pharmaceutical; Computers; Diethylstilbestrol; Drug Compounding; Drug Tolerance; Isoniazid; Mestranol; Methyltestosterone; Models, Theoretical; Paramethasone; Pharmaceutical Preparations; Phenobarbital; Sulfates; Tablets	1970
Encephalopathy following accidental isoniazid poisoning. Clinical pediatrics, 1971, Volume: 10, Issue:6 Topics: Brain Chemistry; Brain Diseases; Child, Preschool; Humans; Isoniazid; Male; Phenobarbital; Pyridoxine; Seizures	1971
[On acute isoniazid poisoning on the basis of 2 successfully treated cases]. Archiv fur Toxikologie, 1967, Volume: 22, Issue:4 Topics: Adult; Alcoholism; Blood Transfusion; Brain; Brain Edema; Gastric Lavage; Glucose; Glutamates; Humans; Isoniazid; Kidney; Male; Nervous System; Phenobarbital; Pyridoxine; Seizures; Suicide; Tuberculosis, Male Genital; Tuberculosis, Pulmonary	1967
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase. Canadian journal of biochemistry, 1968, Volume: 46, Issue:4 Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione	1968
[Acute isoniazid poisoning. Points of onset in the macro-organism, symptoms and measures of treatment]. Beitrage zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten, 1965, Dec-30, Volume: 131, Issue:5 Topics: Amino Acids; Ammonia; Animals; Barbiturates; Biochemical Phenomena; Biochemistry; Blood; Hexobarbital; Humans; Isoniazid; Mice; Phenobarbital; Prognosis; Pyridoxine; Rabbits; Rats; Seizures; Vitamins	1965
Variability of uniformity of weight test as an indicator of the amount of active ingredient in tablets. Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:2 Topics: Chemical Phenomena; Chemistry; Isoniazid; Phenobarbital; Phenylbutazone; Promazine; Tablets; Tolbutamide	1967
[Effects of drug interaction in infancy (author's transl)]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1980, Volume: 128, Issue:10 Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid	1980
Ethanol and isoniazid induce a hepatic microsomal cytochrome P-450-dependent activity with similar properties towards substrate and inhibitors and different properties from those induced by classical inducers. Biochemical pharmacology, 1984, Oct-01, Volume: 33, Issue:19 Topics: Animals; Cytochrome P-450 Enzyme System; Dioxolanes; Enzyme Induction; Ethanol; Imidazoles; Isoniazid; Male; Metyrapone; Microsomes, Liver; Oxidoreductases, O-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry	1984
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2 Topics: Acetylation; Amidohydrolases; Animals; Biotransformation; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Cobalt; Hydrolysis; Isoniazid; Liver; Male; Microsomes, Liver; Nitrophenols; Organophosphorus Compounds; Phenobarbital; Protein Binding; Rats	1980
Epidemiological studies of medically used drugs. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 3 Topics: 2-Naphthylamine; Brain Neoplasms; Epidemiologic Methods; Female; Humans; Isoniazid; Liver Neoplasms; Male; Naphthalenes; Neoplasms; Nitrogen Mustard Compounds; Phenobarbital; Thorium Dioxide; Urinary Bladder Neoplasms	1980
[Metabolic disorders in acute poisoning and their correction by sodium succinate]. Vrachebnoe delo, 1981, Issue:8 Topics: Animals; Antitubercular Agents; Ethionamide; Guinea Pigs; Isoniazid; Phenobarbital; Poisoning; Rifampin; Succinates	1981
Acetylhydrazine hepatotoxicity. Toxicology and applied pharmacology, 1981, Sep-30, Volume: 60, Issue:3 Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Rifampin	1981
Factors affecting acetylhydrazine hepatotoxicity. Advances in experimental medicine and biology, 1981, Volume: 136 Pt B Topics: Animals; Cytochrome P-450 Enzyme System; Hydrazines; Isoniazid; Liver; Male; Necrosis; Phenobarbital; Rats; Rats, Inbred Strains	1981
Investigation of the mechanism of defluorination of enflurane in rat liver microsomes with specifically deuterated derivatives. Biochemical pharmacology, 1980, Jun-01, Volume: 29, Issue:11 Topics: Animals; Biotransformation; Deuterium; Enflurane; In Vitro Techniques; Isoniazid; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Time Factors	1980
[Fulminating hepatitis caused by administration of isoniazid and rifampicin in a patient under chronic treatment with barbiturates]. Nederlands tijdschrift voor geneeskunde, 1980, Jun-21, Volume: 124, Issue:25 Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsy; Female; Hepatic Encephalopathy; Humans; Isoniazid; Phenobarbital; Rifampin; Tuberculosis, Miliary	1980
Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo. Archives of toxicology, 1994, Volume: 68, Issue:6 Topics: Acetone; Adenosine Triphosphate; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Sprague-Dawley; Triglycerides	1994
Increase in liver microsomal glutathione S-transferase activity by phenobarbital treatment of rats. Possible involvement of oxidative activation via cytochrome P450. Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10 Topics: Amitrole; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Ethylmaleimide; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Isoniazid; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley	1993
Popliteal lymph node response to procainamide and isoniazid. Role of beta-naphthoflavone, phenobarbitone and S9-mix pretreatment. Toxicology letters, 1993, Volume: 66, Issue:1 Topics: Animals; Autoimmune Diseases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Drug Evaluation, Preclinical; Enzyme Induction; Female; Isoniazid; Knee; Liver Extracts; Lymph Nodes; Male; Models, Biological; Phenobarbital; Procainamide; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Time Factors	1993
Inhibitory effects of propofol on cytochrome P450 activities in rat hepatic microsomes. Anesthesia and analgesia, 1993, Volume: 76, Issue:4 Topics: Aniline Compounds; Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enflurane; Hydroxylation; Isoniazid; Male; Methylation; Microsomes, Liver; Phenobarbital; Propofol; Rats; Rats, Sprague-Dawley; Toluene	1993
Contrasting effects of 1,1,1-trichloroethane on [14C]vinyl chloride metabolism and activation in hepatic microsomes from phenobarbital- and isoniazid-treated rats. Toxicology and applied pharmacology, 1993, Volume: 119, Issue:1 Topics: Animals; Binding Sites; Biotransformation; Catalase; Cytochrome P-450 Enzyme System; DNA; Drug Interactions; Isoenzymes; Isoniazid; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Sprague-Dawley; Trichloroethanes; Vinyl Chloride	1993
Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver. Archives of toxicology, 1993, Volume: 67, Issue:2 Topics: Animals; Antihypertensive Agents; Benzoflavones; beta-Naphthoflavone; Biotransformation; Clofibrate; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Guinea Pigs; Isoniazid; Liver; Male; Mesocricetus; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar; Species Specificity	1993
The influence of aging on dimethylnitrosamine-demethylase enzyme kinetics in rat liver microsomes. Mechanisms of ageing and development, 1995, Aug-08, Volume: 82, Issue:2-3 Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Glutathione Transferase; Isoniazid; Liver Neoplasms; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred BN	1995
Demonstration of halothane-induced hepatic lipid peroxidation in rats by quantification of F2-isoprostanes. Anesthesiology, 1996, Volume: 84, Issue:4 Topics: Anesthetics, Inhalation; Animals; Dinoprost; Halothane; Isoniazid; Lipid Peroxidation; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley	1996
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:11 Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin	1996
Chlorodibromomethane metabolism to bromide and carbon monoxide in rats. Archives of toxicology, 1997, Volume: 71, Issue:4 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bromides; Carboxyhemoglobin; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Glutathione; Hydrocarbons, Halogenated; Isoniazid; Leucyl Aminopeptidase; Liver; Male; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases; Tissue Distribution; Trihalomethanes; Xylenes	1997
Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes. Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2 Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biomarkers; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Ethylmorphine-N-Demethylase; Female; Isoniazid; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sex Factors	1998
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3 Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics	1999
CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:8 Topics: Animals; beta-Naphthoflavone; Clofenapate; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Glucocorticoids; Glucuronic Acid; Isoenzymes; Isoniazid; Kinetics; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substrate Specificity; Sulfates	2000
Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats. Biopharmaceutics & drug disposition, 2000, Volume: 21, Issue:4 Topics: Amines; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Phenobarbital; Proadifen; Pyrazines; Rats; Rats, Sprague-Dawley	2000
Effects of enzyme inducers or inhibitors on the pharmacokinetics of intravenous parathion in rats. Biopharmaceutics & drug disposition, 2000, Volume: 21, Issue:5 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Insecticides; Isoenzymes; Isoniazid; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Paraoxon; Parathion; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Tissue Distribution	2000
Optimization of an exogenous metabolic activation system for FETAX. I. Post-isolation rat liver microsome mixtures. Drug and chemical toxicology, 2001, Volume: 24, Issue:2 Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); Coumarins; Cyclophosphamide; Embryo, Mammalian; Embryo, Nonmammalian; Isoniazid; Microsomes, Liver; Phenobarbital; Rats; Toxicity Tests; Trichloroethylene; Xenopus laevis	2001
Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation. Drug and chemical toxicology, 2001, Volume: 24, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; beta-Naphthoflavone; Biotransformation; Carbon Tetrachloride; Chloroform; Coculture Techniques; Embryo, Mammalian; Embryo, Nonmammalian; Isoniazid; Microsomes, Liver; Parathion; Phenacetin; Phenobarbital; Rats; Toxicity Tests; Urethane; Xenopus laevis	2001
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:4 Topics: Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hepatocytes; Humans; Isoniazid; Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Rifampin	2003
[ACCIDENTAL INH POISONING IN A 2-YEAR-OLD GIRL]. Pediatria polska, 1964, Volume: 39 Topics: Drug-Related Side Effects and Adverse Reactions; Infant; Isoniazid; Phenobarbital; Seizures; Toxicology	1964
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE. Acta pharmacologica et toxicologica, 1964, Volume: 21 Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology	1964
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats. The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4 Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes	2005
Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium. Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:1 Topics: Animals; Blotting, Western; Cell Survival; Chlorzoxazone; Culture Media; Culture Media, Serum-Free; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; Isoenzymes; Isoniazid; Liver; Male; Microsomes, Liver; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley	2007
Tuberculosis in a patient on temozolomide: a case report. Journal of neuro-oncology, 2009, Volume: 92, Issue:1 Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary	2009