isoniazid and phenelzine

isoniazid has been researched along with phenelzine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199025 (69.44)18.7374
1990's1 (2.78)18.2507
2000's4 (11.11)29.6817
2010's6 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Drayer, DE; Reidenberg, MM1
Besson, S; Catau, G; Notter, D1
Gershbein, LL; Rao, KC1
Clark, DW1
Hovding, G1
Bowman, Z; Cooper, CM; Stanton, HC1
Kupfer, DJ; Robinson, DS; Scott, J; Snyder, F; Wyatt, RJ1
Keiser, H; Lovenberg, W; Robinson, DS; Sjoerdsma, A1
Dal Piaz, V; La Porta, E; Pinzauti, S1
Ishimoto, M; Kagotani, K; Kondo, H; Oshima, M1
Holmes, J; Sapeika, N; Zwarenstein, H1
Hansen, S; Perry, TL1
Evans, DA4
Kalow, W1
Eade, NR; Renton, KW1
Adnitt, PI1
Hargreaves, T1
Schwartz, A; Stanton, HC1
Curran, NM; Lovering, EG; Matsui, F; Robertson, DL; Sears, RW1
BURKARD, W; GEY, KF; PLETSCHER, A1
KOBAYASHI, Y; OTSUKA, S1
KLINE, NS1
HOPPE, E; MEYTHALER, C; SCHMID, E; ZICHA, L1
Elliot, DJ; Gillam, EM; Lewis, BC; Miners, JO; Polasek, TM; Somogyi, AA1

Reviews

5 review(s) available for isoniazid and phenelzine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Genetically determined variability in acetylation and oxidation. Therapeutic implications.
    Drugs, 1985, Volume: 29, Issue:4

    Topics: Acetylation; Anticonvulsants; Antidepressive Agents, Tricyclic; Debrisoquin; Disease; Drug Interactions; Genetic Variation; Humans; Hydralazine; Isoniazid; Oxidation-Reduction; Pharmaceutical Preparations; Phenelzine; Phenotype; Procainamide; Racial Groups; Sparteine; Sulfasalazine

1985
Genetic factors in drug therapy.
    The Scientific basis of medicine annual reviews, 1969

    Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; Hydralazine; Isoniazid; Liver; Male; Myocardial Infarction; Pharmaceutical Preparations; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenytoin; Polymorphism, Genetic; Polyneuropathies; Streptomycin; Sulfamethazine; Tuberculosis, Pulmonary

1969
Topics in pharmacogenetics.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Acyltransferases; Anesthetics; Drug Hypersensitivity; Fever; Gene Frequency; Genetics, Medical; Humans; Isoniazid; Liver; Muscular Diseases; Pharmacogenetics; Phenelzine; Sulfonamides; Tuberculosis

1971

Other Studies

31 other study(ies) available for isoniazid and phenelzine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Clinical consequences of polymorphic acetylation of basic drugs.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3

    Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Pharmaceutical Preparations; Phenelzine; Phenotype; Polymorphism, Genetic; Procainamide; Sulfasalazine

1977
[Effect of an MAO inhibitor, phenelzine, on acetylation of isoniazid by isolated perfused rat liver].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1978, Volume: 172, Issue:3

    Topics: Acetylation; Animals; In Vitro Techniques; Isoniazid; Liver; Male; Perfusion; Phenelzine; Rats

1978
Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats.
    Oncology research, 1992, Volume: 4, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Hydralazine; Injections, Subcutaneous; Isoniazid; Male; Phenelzine; Rats; Rats, Inbred Strains

1992
Occupational dermatitis from hydrazine hydrate used in boiler protection. Cross sensitization to apresoline, isoniazid and phenelzine.
    Acta dermato-venereologica, 1967, Volume: 47, Issue:5

    Topics: Adult; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Humans; Hydralazine; Hydrazines; Isoniazid; Male; Phenelzine; Skin Tests

1967
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine

1970
Longitudinal studies of the effect of monoamine oxidase inhibitors on sleep in man.
    Psychopharmacologia, 1969, Volume: 15, Issue:3

    Topics: Blood Platelets; Depression; Female; Humans; Hydrazines; Isocarboxazid; Isoniazid; Male; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Placebos; Sleep; Sleep Stages; Sleep, REM; Tryptamines

1969
Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo.
    Biochemical pharmacology, 1968, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amines; Animals; Benzene Derivatives; Blood Platelets; Carbon Isotopes; Cyanides; Female; Furazolidone; Humans; Hydrazines; In Vitro Techniques; Iproniazid; Isocarboxazid; Isoniazid; Kinetics; Male; Middle Aged; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Plasma; Rats; Tranylcypromine; Tryptamines

1968
Chloramine-T as titrimetric reagent in potentiometric determination of isoniazid, phenelzine, and dihydralazine.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:9

    Topics: Chloramines; Chromatography, Thin Layer; Hydralazine; Indicators and Reagents; Isoniazid; Oxidation-Reduction; Phenelzine; Potentiometry; Temperature

1974
Purification and some properties of taurine dehydrogenase from a bacterium.
    Journal of biochemistry, 1973, Volume: 73, Issue:6

    Topics: Ammonium Sulfate; Bacteria; Chloromercuribenzoates; Chromatography, Gel; Isoniazid; Japan; Oxidoreductases; Phenelzine; Taurine; Water Microbiology

1973
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts

1973
Sustained drug-induced elevation of brain GABA in the rat.
    Journal of neurochemistry, 1973, Volume: 21, Issue:5

    Topics: Acetates; Administration, Oral; Alanine; Aminobutyrates; Animals; Brain; Brain Chemistry; Dipeptides; Histidine; Hydroxylamines; Isoniazid; Phenelzine; Rats

1973
Microsomal enzymes and potentiation of tyramine pressor response.
    Biochemical pharmacology, 1972, May-15, Volume: 21, Issue:10

    Topics: Animals; Blood Pressure; Drug Synergism; Enzyme Induction; In Vitro Techniques; Isoniazid; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Phenelzine; Phenobarbital; Proadifen; Rats; Subcellular Fractions; Time Factors; Tyramine

1972
Monoamineoxidase inhibition and insulin sensitivity.
    The Journal of endocrinology, 1968, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Drug Synergism; Feeding and Eating Disorders; Growth Hormone; Humans; Hydrazines; Hypoglycemia; Insulin; Isoniazid; Liver; Male; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Rats; Tranylcypromine

1968
Pharmacogenetics.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Aged; Cortisone; Enzyme Induction; Female; Glaucoma; Humans; Hydralazine; Intraocular Pressure; Isoniazid; Male; Nortriptyline; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenylbutazone; Polymorphism, Genetic; Pregnancy; Sulfamethazine; Twins

1970
The effect of monoamine oxidase inhibitors on conjugation.
    Experientia, 1968, Feb-15, Volume: 24, Issue:2

    Topics: Animals; Bilirubin; Endoplasmic Reticulum; Glucosyltransferases; Glucuronates; In Vitro Techniques; Iproniazid; Isocarboxazid; Isoniazid; Jaundice; Liver; Nialamide; Phenelzine; Phenols; Rabbits; Rats

1968
Effects of a hydrazine monoamine oxidase inhibitor (phenelzine) on isoproterenol-induced myocardiopathies in the rat.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:3

    Topics: Animals; Blood Pressure; Female; Heart Diseases; Heart Rate; Iproniazid; Isoniazid; Isoproterenol; Mitochondria; Myocardium; Nucleic Acids; Phenelzine; Rats; Water-Electrolyte Balance

1967
Hydrazine levels in formulations of hydralazine, isoniazid, and phenelzine over a 2-year period.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:8

    Topics: Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Phenelzine; Solutions; Tablets; Time Factors

1983
Effect of inhibitors of monoamine oxidase on various enzymes and on the storage of monoamines.
    Annals of the New York Academy of Sciences, 1963, Jul-08, Volume: 107

    Topics: Amines; Carboxy-Lyases; Humans; Hydrazines; Iproniazid; Isoniazid; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Oxidoreductases; Phenelzine; Tranylcypromine

1963
ENZYMES AND DRUG SENSITIVITY. ACETYLATION POLYMORPHISMS.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acetylation; Aminosalicylic Acid; Aminosalicylic Acids; Biomedical Research; Genetics, Medical; Hydralazine; Isoniazid; Liver; Metabolism; Monoamine Oxidase Inhibitors; Phenelzine; Toxicology

1964
RADIOISOTOPIC ASSAY FOR MONOAMINE OXIDASE DETERMINATIONS IN HUMAN PLASMA.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Amine Oxidase (Copper-Containing); Azides; Blood Chemical Analysis; Carbon Isotopes; Edetic Acid; Guanidines; Humans; Hydrazines; Iproniazid; Isoniazid; Monoamine Oxidase; Phenelzine; Radioisotopes; Radionuclide Imaging; Solvents; Tranylcypromine; Tyramine

1964
THE PRACTICAL MANAGEMENT OF DEPRESSION.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: Amitriptyline; Antidepressive Agents; Benzoates; Classification; Depression; Depressive Disorder; Drug Therapy; Electroconvulsive Therapy; Imipramine; Isocarboxazid; Isoniazid; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Phentolamine; Psychopharmacology; Psychotherapy; Reserpine; Sulfates; Toxicology; Tranylcypromine; Vitamin B 12

1964
[THIN LAYER CHROMATOGRAPHIC SEPARATION OF PSYCHOPHARMACOLOGICAL AGENTS WITH ANTIDEPRESSIVE ACTION].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Amitriptyline; Antidepressive Agents; Chromatography; Chromatography, Thin Layer; Desipramine; Hydrazines; Imipramine; Iproniazid; Isocarboxazid; Isoniazid; Nialamide; Phenelzine; Research; Tranylcypromine

1963
CONJOINT CLINIC ON DRUGS AND GENES.
    Journal of chronic diseases, 1965, Volume: 18

    Topics: Acetates; Aminosalicylic Acid; Aminosalicylic Acids; Coenzyme A; Diabetes Mellitus; Genetics, Medical; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Hydralazine; Insulin; Isoniazid; Kidney; Liver; Metabolism; Neuritis; Pharmacology; Phenelzine; Sulfamethazine; Toxicology

1965
An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:5

    Topics: Aryl Hydrocarbon Hydroxylases; Clorgyline; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isoniazid; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Phenelzine; Tissue Culture Techniques; Ultrafiltration

2006