isoniazid and nadp

isoniazid has been researched along with nadp in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199018 (66.67)18.7374
1990's2 (7.41)18.2507
2000's6 (22.22)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corcoran, GB; Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA1
Valla, D1
Bui, QD; Weisz, J; Wrighton, SA1
Levin, W; Oldfield, N; Ryan, DE; Thomas, PE1
Shah, NS1
Martin, SP; Shah, NS1
Collins, P; Winder, F1
Bartmann, K; Coper, H; Jütte, R1
Eady, RR; Large, PJ1
Collins, P; Winder, FG1
Baldry, CW; Bucke, C; Coombs, J1
Kutt, H; Verebely, K1
Bernard, S; Le Cam, M; Madec, Y1
Turner, JM; Willetts, AJ1
Heard, JT; Tritz, GJ1
Bidlack, WR; Muakkassah, SF; Yang, WC1
Albano, E; French, SW; Hagbjork, AL; Ingelman-Sundberg, M; Jui, L; Wong, K1
Backman, JT; Neuvonen, PJ; Wang, JS; Wen, X1
Choi, D; Kim, YC; Leininger-Muller, B; Leroy, P; Siest, G; Wellman, M1
SEKI, S1
MAAYAN, ML1
Bernadou, J; Cohen-Gonsaud, M; Daffé, M; Ducasse-Cabanot, S; Labesse, G; Marrakchi, H; Nguyen, M; Quémard, A; Zerbib, D1
Aladegbami, B; Argyrou, A; Blanchard, JS; Vetting, MW1
Bernadou, J; Bernardes-Génisson, V; Delaine, T; Meunier, B1
Argyrou, A; Blanchard, JS; Vetting, MW1
French, NS; Maggs, JL; Meng, X; Naisbitt, DJ; Park, BK; Usui, T; Whitaker, P1
Baquer, NZ; Hornbruch, A; McLean, P; Wolpert, L1

Other Studies

27 other study(ies) available for isoniazid and nadp

ArticleYear
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat.
    Science (New York, N.Y.), 1976, Sep-03, Volume: 193, Issue:4256

    Topics: Animals; Chemical and Drug Induced Liver Injury; Humans; Hydrazines; Iproniazid; Isoniazid; Microsomes, Liver; NADP; Rats; Structure-Activity Relationship

1976
[Hepatic metabolism of foreign substances. Enzymatic hydroxylation system of hepatic microsomes and of cytochrome P-450].
    Medecine & chirurgie digestives, 1978, Volume: 7, Issue:3

    Topics: Anticoagulants; Benzopyrenes; Biotransformation; Cytochrome P-450 Enzyme System; Epoxy Compounds; Ethanol; Humans; Hydroxylation; Iproniazid; Isoniazid; Liver; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Phenobarbital

1978
Hepatic catecholestrogen synthases: differential effect of sex, inducers of cytochromes P-450 and of antibody to the glucocorticoid inducible cytochrome P-450 on NADPH-dependent estrogen-2-hydroxylase and on organic hydroperoxide-dependent estrogen-2/4-hy
    The Journal of steroid biochemistry and molecular biology, 1990, Volume: 37, Issue:2

    Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Estradiol; Estrogens, Catechol; Female; Isoniazid; Kinetics; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors

1990
N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: isozyme specificity and role of cytochrome b5.
    Archives of biochemistry and biophysics, 1986, Volume: 248, Issue:1

    Topics: Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Dimethylnitrosamine; Ethanol; Formaldehyde; Hydrogen-Ion Concentration; Isoenzymes; Isoniazid; Kinetics; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Rats

1986
Isocitric dehydrogenase and nicotinamide adenine dinucleotidase in experimental tuberculosis: influence of isoniazid on metabolic damage.
    The American review of respiratory disease, 1967, Volume: 95, Issue:2

    Topics: Animals; Guinea Pigs; Isocitrate Dehydrogenase; Isoniazid; Kidney; Male; NAD; NADP; Nucleotidases; Tuberculosis

1967
Further studies with isocitric dehydrogenase in experimental tuberculosis: influence of isoniazid on metabolic damage.
    The American review of respiratory disease, 1967, Volume: 95, Issue:6

    Topics: Animals; Azoles; Colorimetry; Guinea Pigs; Iproniazid; Isocitrate Dehydrogenase; Isoniazid; Kidney; Male; Mycobacterium tuberculosis; NAD; NADP; Nicotinic Acids; Phenazines; Spectrophotometry; Tuberculosis, Renal

1967
The effect of isoniazid on nicotinamide nucleotide levels in Mycobacterium bovis, strain BCG.
    The American review of respiratory disease, 1968, Volume: 97, Issue:4

    Topics: Isoniazid; Mycobacterium bovis; NAD; NADP

1968
[NAD(P)-glycohydrolase in tuberculosis bacteria. A contribution to the mechanism of action INH].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Isoniazid; Isonicotinic Acids; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; NADP

1967
Purification and properties of an amine dehydrogenase from Pseudomonas AM1 and its role in growth on methylamine.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Amines; Amino Alcohols; Chloromercuribenzoates; Chromatography, Gel; Coloring Agents; Cytochromes; Electron Transport; Ferricyanides; Flavins; Histamine; Hydrogen-Ion Concentration; Isoniazid; Kinetics; NAD; NADP; Oxidoreductases; Oxygen; Phenazines; Pseudomonas; Quinacrine; Semicarbazides; Spectrophotometry; Succinates; Temperature; Vitamin K

1968
The effect of isoniazid on nicotinamide nucleotide concentrations in tubercle bacilli. A correction and further observations.
    The American review of respiratory disease, 1969, Volume: 100, Issue:1

    Topics: Isoniazid; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; NAD; NADP; Time Factors

1969
Light-phosphoenolpyruvate dependent carbodioxide fixation by isolated sugar cane chloroplasts.
    Biochemical and biophysical research communications, 1969, Nov-20, Volume: 37, Issue:5

    Topics: Amides; Aspartate Aminotransferases; Benzoates; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chloroplasts; Edetic Acid; Glycerophosphates; Isoniazid; Kinetics; Light; Malonates; NADP; Oxaloacetates; Phenanthrolines; Phosphates; Pyruvates; Ultracentrifugation; Urea

1969
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature

1970
[Metabolic behavior of Mycobacterium tuberculosis strain H37 Ra under action of rifampicin, comparison with isoniazid].
    Annales de l'Institut Pasteur, 1971, Volume: 120, Issue:2

    Topics: Adenosine Triphosphate; Fructose-Bisphosphate Aldolase; Glycolysis; Isoniazid; Mycobacterium tuberculosis; NAD; NADP; Pyruvate Kinase; Rifampin; Transaminases

1971
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
    Biochimica et biophysica acta, 1971, Volume: 252, Issue:1

    Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases

1971
Isoniazid perturbation of the pyridine nucleotide cycle of Escherichia coli.
    Microbios, 1982, Volume: 35, Issue:141-142

    Topics: Escherichia coli; Isoniazid; Mutation; NAD; NADP; Niacin; Niacinamide; Nicotinamide Mononucleotide

1982
Mechanism of the inhibitory action of isoniazid on microsomal drug metabolism.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoniazid; Male; Microsomes, Liver; NADP; Oxygen Consumption; Rats

1981
Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis.
    Experimental and molecular pathology, 1993, Volume: 58, Issue:1

    Topics: Aldehydes; Animals; Blood Proteins; Cytochrome P-450 Enzyme System; Dietary Fats; Dose-Response Relationship, Drug; Ethanol; Isoniazid; Lipid Metabolism; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Microscopy, Electron; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Transaminases

1993
Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    European journal of clinical pharmacology, 2002, Volume: 57, Issue:11

    Topics: Antitubercular Agents; Aryl Hydrocarbon Hydroxylases; Biomarkers; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Isoenzymes; Isoniazid; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP

2002
Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging ability of isoniazid.
    Free radical research, 2002, Volume: 36, Issue:8

    Topics: Animals; Cell Line; Cells, Cultured; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Free Radicals; Humans; Isoniazid; Lipopolysaccharides; Liver; Male; Microsomes; NADP; Oxygen; Protease Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transfection

2002
EFFECTS OF NICOTINAMIDE, ISONICOTINIC ACID HYDRAZIDE, AND 3-ACETYLPYRIDINE ON THE GROWTH AND NICOTINAMIDE ADENINE DINUCLEOTIDE CONTENT OF L CELLS.
    Acta medicinae Okayama, 1963, Volume: 17

    Topics: Alcohol Oxidoreductases; Cell Division; Isoniazid; NAD; NADP; Niacin; Niacinamide; Pharmacology; Pyridines; Research; Research Design; Tissue Culture Techniques

1963
NAD+-GLYCOHYDROLASE OF THYROID HOMOGENATES.
    Nature, 1964, Dec-19, Volume: 204

    Topics: Animals; Biochemical Phenomena; Biochemistry; Diiodotyrosine; Isoniazid; Metabolism; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; NADP; Niacin; Niacinamide; Rats; Research; Spectrophotometry; Swine; Thyroid Gland

1964
In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:1

    Topics: Acyl Carrier Protein; Antitubercular Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crystallography, X-Ray; Fatty Acids; Isoniazid; Models, Molecular; Mycobacterium tuberculosis; NADP; Protein Conformation; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization

2004
Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid.
    Nature structural & molecular biology, 2006, Volume: 13, Issue:5

    Topics: Cell Proliferation; Cloning, Molecular; Crystallography, X-Ray; Folic Acid Antagonists; Gene Expression; Isoniazid; Models, Molecular; Mycobacterium tuberculosis; NADP; Prodrugs; Protein Binding; Protein Structure, Tertiary; Tetrahydrofolate Dehydrogenase

2006
Synthesis of the isonicotinoylnicotinamide scaffolds of the naturally occurring isoniazid-NAD(P) adducts.
    The Journal of organic chemistry, 2007, Jan-19, Volume: 72, Issue:2

    Topics: Isoniazid; Molecular Structure; NADP

2007
New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP.
    Journal of the American Chemical Society, 2007, Aug-08, Volume: 129, Issue:31

    Topics: Bacterial Proteins; Drug Resistance, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Hydrazines; Isoniazid; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; NADP; Niacin; Oxidoreductases

2007
Auto-oxidation of Isoniazid Leads to Isonicotinic-Lysine Adducts on Human Serum Albumin.
    Chemical research in toxicology, 2015, Jan-20, Volume: 28, Issue:1

    Topics: Adult; Aged, 80 and over; Female; Humans; Isoniazid; Lysine; Male; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Protein Binding; Serum Albumin

2015
Positional information and pattern regulation in hydra: enzyme profiles.
    Journal of embryology and experimental morphology, 1975, Volume: 33, Issue:4

    Topics: Alanine Transaminase; Animals; Brain; Carbon Dioxide; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; Hydra; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Mammary Glands, Animal; NAD; NADP; Oligomycins

1975