isoniazid has been researched along with mercaptopurine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Buselmaier, W; Herbold, B | 1 |
| Katsambas, A; Stratigos, JD | 1 |
| Boudreaux, D; Gabor, EP; Kuberski, TT | 1 |
| Glogner, P | 1 |
| Gault, MH; Hebert, MA; Singh, HP | 1 |
| Kern, F; Mallory, A | 1 |
| Hiratsuka, M | 1 |
| CAFARO, C | 1 |
3 review(s) available for isoniazid and mercaptopurine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug-induced pancreatitis: a critical review.
Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Cholestyramine Resin; Cimetidine; Cyproheptadine; Dextropropoxyphene; Diazoxide; Diuretics; Estrogens; Ethacrynic Acid; Furosemide; Histamine; Humans; Hypercalcemia; Indomethacin; Isoniazid; Mercaptopurine; Narcotics; Pancreatitis; Phenformin; Procainamide; Rifampin; Salicylates; Sodium Chloride Symporter Inhibitors; Sulfonamides; Tetracycline | 1980 |
[Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications].
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Arylamine N-Acetyltransferase; Biotransformation; Cytochrome P-450 Enzyme System; DNA, Mitochondrial; Genotype; Humans; Isoniazid; Male; Mercaptopurine; Methyltransferases; Pharmacogenetics; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Tolbutamide | 2002 |
18 other study(ies) available for isoniazid and mercaptopurine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Induction of point mutations by different chemical mechanisms in the liver microsomal assay.
Topics: Animals; Azathioprine; Biotransformation; Captan; Cyclophosphamide; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Genetic Code; Hydrazines; Isoniazid; Male; Mercaptopurine; Methotrexate; Methylnitronitrosoguanidine; Mice; Microsomes, Liver; Mutagens; Protein Biosynthesis; Salmonella typhimurium | 1976 |
Pellagra: a still existing disease.
Topics: Alcoholism; Diet; Fluorouracil; Humans; Intestinal Absorption; Isoniazid; Mercaptopurine; Nicotinic Acids; Pellagra; Tryptophan | 1977 |
Disseminated strongyloidiasis. A complication of the immunosuppressed host.
Topics: Acute Disease; Adult; Animals; Female; Humans; Immunosuppression Therapy; Immunotherapy; Isoniazid; Jejunum; Leukemia, Lymphoid; Mercaptopurine; Prednisone; Radiography, Abdominal; Radiography, Thoracic; Strongyloides; Strongyloidiasis; Vincristine | 1975 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Ephedrine; Humans; Hypertension; Hypotension; Isoniazid; Mercaptopurine; Methamphetamine; Microsomes, Liver; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Phenytoin; Reserpine; Stimulation, Chemical; Thiazines; Thiopental; Tyramine | 1970 |
Effect of some drugs on clinical laboratory values as determined by the Technicon SMA 12-60.
Topics: Acetaminophen; Alkaline Phosphatase; Aminosalicylic Acids; Ascorbic Acid; Aspartate Aminotransferases; Autoanalysis; Bilirubin; Blood Chemical Analysis; Blood Glucose; Chemical Phenomena; Chemistry; Cholesterol; Clinical Laboratory Techniques; Dihydroxyphenylalanine; Evaluation Studies as Topic; Humans; Isoniazid; L-Lactate Dehydrogenase; Mercaptopurine; Methyldopa; Pharmaceutical Preparations; Spectrophotometry; Sulfathiazoles; Uric Acid | 1972 |
[ALTERATIONS OF THE CENTRAL NERVOUS SYSTEM IN ACUTE LEUKEMIAS].
Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Blood Transfusion; Bone Marrow Examination; Central Nervous System Diseases; Child; Dextrans; Hematoma; Hematoma, Subdural; Humans; Isoniazid; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Norepinephrine; Oleandomycin; Paraplegia; Prednisone; Streptomycin; Tetracycline | 1964 |