isoniazid and linezolid

isoniazid has been researched along with linezolid in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (20.00)	29.6817
2010's	29 (52.73)	24.3611
2020's	15 (27.27)	2.80

Authors

Authors	Studies
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Biswas, K; Crick, DC; Dhiman, R; Kurosu, M; Narayanasamy, P	1
Barbachyn, MR; Brickner, SJ; Hutchinson, DK; Manninen, PR	1
Lombardo, F; Obach, RS; Waters, NJ	1
Amirthaganesan, S; Aridoss, G; Jeong, YT; Kabilan, S; Kim, JT; Kumar, NA; Lim, KT	1
Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z	1
Angulo-Barturen, I; Beltrán, M; Cáceres, N; Cardona, PJ; García, JI; García-Bustos, JF; Rullas, J	1
Bishai, WR; Grosset, JH; Nuermberger, EL; Zhang, T	1
Baulard, AR; Crauste, C; Déprez, B; Flipo, M; Villemagne, B; Willand, N	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Ang, W; Deng, Y; Liu, Y; Luo, Y; Sang, Z; Wei, Y; Yang, T; Ye, W	1
Achar, V; Ambady, A; Awasthy, D; Bandodkar, B; Bellale, E; Chatterji, M; Guptha, S; Kaur, P; McLaughlin, R; Morayya, S; Naik, M; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, V; Ravishankar, S; Sharma, S; V B, V; Vachaspati, P; Whiteaker, J	1
Biava, M; Cocozza, M; Consalvi, S; Poce, G	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Mahajan, SS; Saharan, VD	1
Chang, L; Feng, LS; Gao, C; Lv, ZS; Ren, QC; Xu, Z; Zhang, S	1
Bonnet, M; Cooper, CB; Denny, WA; Franzblau, SG; Lee, HH; Thompson, AM; Wan, B; Wong, GS	1
Eslamimehr, S; Franzblau, SG; Kong, Y; Kurosu, M; Lemieux, MR; Mitachi, K; Park, F; Pressly, JD; Siricilla, S; Wang, Y; Yang, D	1
Eswaran, S; Narayanan, S; Shivarudraiah, P; Shruthi, TG; Subramanian, S	1
Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K	1
Mabhula, A; Singh, V	1
Barreca, ML; Bojarski, AJ; Cecchetti, V; Cook, GM; Desantis, J; Felicetti, T; Franzblau, SG; Handzlik, J; Hards, K; Kolář, MH; Latacz, G; Manfroni, G; Massari, S; Mazzarella, MA; Nakatani, Y; Nizi, MG; Rushton-Green, R; Sabatini, S; Satała, G; Shetye, G; Tabarrini, O	1
Fu, L; Huang, H; Li, G; Li, Y; Liu, Y; Lu, H; Lu, Y; Ma, C; Sheng, L; Wang, B; Zhang, B; Zhang, D; Zhao, H	1
Aldrich, CC; Baughn, AD; Boshoff, HIM; Dartois, V; Hegde, PV; Howe, MD; Jia, Z; Pan, Y; Remache, B; Sharma, S; Zimmerman, MD	1
Castagnolo, D; Denny, WA; Dos Santos, JL; Fernandes, GFS; Thompson, AM	1
González-Lahoz, JM; Laguna, F; Moreno, V; Valencia, ME	1
Cynamon, MH; DeStefano, MS; Monica, BJ; Shoen, CM; Sklaney, MR; Slee, AM	1
Rao, M; Rattan, A; Singhal, S; Sood, R	1
Boom, WH; Debanne, SM; Dietze, R; Eisenach, K; Hadad, DJ; Johnson, DF; Johnson, JL; Maciel, EL; McGee, B; Molino, LP; Palaci, M; Peloquin, CA	1
Bilgin, K; Coban, AY; Durupinar, B; Uzun, M	1
Alffenaar, JW; de Neeling, H; Simons, S; van de Kasteele, PJ; van der Laan, T; van der Werf, TS; van Soolingen, D	1
Barbedo, J; Centis, R; D'Ambrosio, L; Diogo, N; Fernandes, L; Lange, C; Migliori, GB; Raymundo, E; Sotgiu, G; Villar, M	1
Chang, KC; Leung, CC; Tam, CM; Yew, WW	1
Fu, L; Guo, Z; Li, P; Liu, S; Mu, X; Wang, B; Zhao, W; Zheng, M	1
Blackmore, T; McNaughton, A; McNaughton, H	1
Mendel, C; Murray, S; Spigelman, M	1
Caminero, JA; Migliori, GB; Piubello, A; Scardigli, A	1
An, J; Bai, X; Cai, H; Chu, N; Gao, M; Huang, C; Huang, H; Li, B; Li, L; Pang, Y; Xu, H; Zhang, F; Zhang, X	1
Baldin, VP; Caleffi-Ferracioli, KR; Campanerut-Sá, PAZ; Cardoso, RF; de Almeida, AL; Nakamura de Vasconcelos, SS; Santos, NCS; Scodro, RBL; Siqueira, VLD	1
Ader, F; Bernard-Barret, F; Dumitrescu, O; Genestet, C; Ginevra, C; Goutelle, S; Hodille, E; Lina, G	1
Ahmad, J; Rana, P; Roy, V	1
Ahn, H; Cho, YJ; Choi, HS; Choi, SM; Hahn, S; Han, J; Heo, EY; Hwang, YR; Jeong, I; Jo, YS; Joh, JS; Ki, J; Kim, DK; Kim, H; Kim, HS; Kim, J; Kim, SJ; Kwak, N; Lee, CH; Lee, J; Lee, JH; Lee, JK; Lee, JY; Lee, M; Lee, SH; Lee, SM; Lee, YJ; Lim, JN; Park, JH; Park, JS; Park, SS; Park, YS; Song, T; Yim, JJ; Yoon, HI	1
Bang, H; Barry, CE; Dartois, V; Eum, S; Fox, WS; Gupta, SV; Lee, M; Savic, RM; Shim, T; Strydom, N; Via, LE; Zimmerman, M	1
Burger, DA; Dawson, R; De Jager, VR; Diacon, AH; Everitt, D; Mendel, CM; Narunsky, K; Nedelman, J; Pappas, F; Vanker, N	1
Caleffi-Ferracioli, KR; Cardoso, RF; Costacurta, GF; da Silva, LA; de Almeida, AL; de Pádua, RA; do Prado, SM; Ghiraldi Lopes, LD; Ieque, AL; Leal, DC; Micheletti, DF; Sampiron, EG; Santos, NCS; Scodro, RBL; Siqueira, VL	1
Andersson, B; Das, J; Kalsum, S; Lerm, M; Schön, T	1
Baluku, JB; Bongomin, F; Katuramu, R; Kizito, E; Nabwana, M; Naloka, J	1
Bremond-Gignac, D; Lortholary, O; Nguyen, DT; Orssaud, C; Pavie, J; Pinot, J; Robert, MP; Rouzaud, C	1
Chen, X; Ding, Y; Fu, L; Guo, S; Liu, H; Lu, Y; Wang, B; Wang, N; Zhang, W; Zhu, H	1
Kamoshita, F; Karaushi, H; Mitsutake, K; Miyawaki, Y; Seki, M; Watanabe, N	1
Avihingsanon, A; Balanag, VM; Burhan, E; Chew, KL; Cousins, C; Crook, AM; Dalay, VB; Djaharuddin, I; Kusmiati, T; Lee, SL; Lu, Q; Nunn, AJ; Papineni, P; Paton, NI; Pokharkar, Y; Ruslami, R; Sarin, R; Sekaggya-Wiltshire, C; Sugiri, JJR; Suresh, C; Veto, RS	1
Alffenaar, JW; Aryal, S; Boorgula, GD; Dheda, K; Gumbo, T; Malinga, L; Raj, P; Shankar, P; Singh, S; Srivastava, S; Thomas, TA	1
Aalhoul, F; Cotton, F; Fage, D	1
Adeel, A; Ahmad, A; Ahmad, I; Aslam, H; Mushtaq, F; Raza, SM; Saleem, S	1

Reviews

10 review(s) available for isoniazid and linezolid

Article	Year
Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones	2008
Tuberculosis: the drug development pipeline at a glance. European journal of medicinal chemistry, 2012, Volume: 51 Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Drug Discovery; Humans; Tuberculosis	2012
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development. European journal of medicinal chemistry, 2014, Oct-30, Volume: 86 Topics: Animals; Antitubercular Agents; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant	2014
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Triazole derivatives and their anti-tubercular activity. European journal of medicinal chemistry, 2017, Sep-29, Volume: 138 Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Tuberculosis	2017
Recent advancements in mechanistic studies and structure activity relationship of F European journal of medicinal chemistry, 2019, Nov-15, Volume: 182 Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship	2019
Drug-resistance in MedChemComm, 2019, Aug-01, Volume: 10, Issue:8 Topics:	2019
Tuberculosis Drug Discovery: Challenges and New Horizons. Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11 Topics: Antitubercular Agents; COVID-19 Drug Treatment; Drug Discovery; Humans; Mycobacterium tuberculosis; Tuberculosis	2022
WHO group 5 drugs and difficult multidrug-resistant tuberculosis: a systematic review with cohort analysis and meta-analysis. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Acetamides; Adult; Antitubercular Agents; beta-Lactams; Clofazimine; Cohort Studies; Databases, Bibliographic; Female; Fluoroquinolones; Humans; Isoniazid; Linezolid; Macrolides; Male; Oxazolidinones; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2013
[Screening and prevention of toxic optic neuropathies due to anti-mycobacterium therapies: proposal of recommendations]. Journal francais d'ophtalmologie, 2022, Volume: 45, Issue:5 Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Linezolid; Toxic Optic Neuropathy	2022

Trials

5 trial(s) available for isoniazid and linezolid

Article	Year
Short-course treatment regimen to identify potential antituberculous agents in a murine model of tuberculosis. The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:4 Topics: Acetamides; Animals; Antitubercular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Fluoroquinolones; Gatifloxacin; Isoniazid; Linezolid; Mice; Mice, Inbred C57BL; Oxazolidinones; Rifampin; Time Factors; Tuberculosis	2004
Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis. American journal of respiratory and critical care medicine, 2008, Dec-01, Volume: 178, Issue:11 Topics: Acetamides; Adult; Antibiotics, Antitubercular; Colony Count, Microbial; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Linezolid; Male; Middle Aged; Oxazolidinones; Sputum; Tuberculosis, Pulmonary; Young Adult	2008
Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: a prospective, multicentre, randomised, open-label, phase 2 trial. The Lancet. Infectious diseases, 2019, Volume: 19, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Substitution; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Linezolid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult	2019
Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis. Antimicrobial agents and chemotherapy, 2020, 03-24, Volume: 64, Issue:4 Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Linezolid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; South Africa; Sputum; Tuberculosis, Pulmonary	2020
Treatment Strategy for Rifampin-Susceptible Tuberculosis. The New England journal of medicine, 2023, Mar-09, Volume: 388, Issue:10 Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Linezolid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2023

Other Studies

40 other study(ies) available for isoniazid and linezolid

Article	Year
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens. Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17 Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Benzophenones; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; Mycobacterium; Naphthols; Staphylococcus aureus; Staphylococcus epidermidis	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives. Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24 Topics: Anti-Bacterial Agents; Antitubercular Agents; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drug Resistance, Microbial; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Chemical; Models, Molecular; Piperidines; Piperidones; Pyridines; Rifampin	2008
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins	2009
Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Acetamides; Animals; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Discovery; Ethambutol; Fluoroquinolones; Immunocompetence; Inhalation Exposure; Isoniazid; Linezolid; Mice; Mice, Inbred C57BL; Moxifloxacin; Oxazolidinones; Pyrazinamide; Quinolines; Reproducibility of Results; Rifampin; Tuberculosis, Pulmonary	2010
Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Anti-Bacterial Agents; Erythromycin; Luminescent Proteins; Microbial Sensitivity Tests; Models, Genetic; Mycobacterium ulcerans; Reserpine; Tetracycline	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents. Bioorganic & medicinal chemistry letters, 2014, Mar-15, Volume: 24, Issue:6 Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Drug Evaluation, Preclinical; Escherichia coli; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Oxazolidinones; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Vero Cells	2014
Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; High-Throughput Screening Assays; Humans; Mice; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Polymorphism, Single Nucleotide; Protein Kinases; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles	2014
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis. Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4 Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis	2017
Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid. ACS medicinal chemistry letters, 2017, Dec-14, Volume: 8, Issue:12 Topics:	2017
An antimycobacterial pleuromutilin analogue effective against dormant bacilli. Bioorganic & medicinal chemistry, 2018, 09-15, Volume: 26, Issue:17 Topics: Administration, Oral; Animals; Antitubercular Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Diterpenes; Female; Half-Life; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pleuromutilins; Polycyclic Compounds	2018
Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 1,2,4-oxadiazole moiety. Bioorganic & medicinal chemistry letters, 2019, 01-01, Volume: 29, Issue:1 Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Quinolines; Structure-Activity Relationship	2019
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. European journal of medicinal chemistry, 2020, Sep-01, Volume: 201 Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Synergism; Enzyme Inhibitors; HEK293 Cells; Humans; Microsomes, Liver; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADH Dehydrogenase; Organoselenium Compounds; Parasitic Sensitivity Tests; Phenothiazines; Protein Binding; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Vero Cells	2020
Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis. Journal of medicinal chemistry, 2020, 09-10, Volume: 63, Issue:17 Topics: Animals; Chlorocebus aethiops; Drug Design; Female; Hep G2 Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Oxazolidinones; Safety; Tuberculosis, Multidrug-Resistant; Vero Cells	2020
Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS). European journal of medicinal chemistry, 2022, Mar-15, Volume: 232 Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Biological Availability; Mice; Prodrugs; Tuberculosis; Tuberculosis, Multidrug-Resistant	2022
[Multiresistant tuberculosis caused by Mycobacterium bovis and human immunodeficiency virus infection. Are there new therapeutic possibilities?]. Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:1 Topics: Acetamides; Adult; AIDS-Related Opportunistic Infections; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Clavulanic Acid; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Isoniazid; Linezolid; Mycobacterium bovis; Oxazolidinones; Thioacetazone; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2001
Activity of RBx 7644 and RBx 8700, new investigational oxazolidinones, against Mycobacterium tuberculosis infected murine macrophages. International journal of antimicrobial agents, 2005, Volume: 25, Issue:6 Topics: Acetamides; Animals; Antitubercular Agents; Cell Line; Drug Antagonism; Furans; Isoniazid; Linezolid; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Rifampin	2005
[Effect of linezolid in combination with isoniazid and rifampicin against multidrug resistant Mycobacterium tuberculosis clinical isolates]. Mikrobiyoloji bulteni, 2009, Volume: 43, Issue:2 Topics: Acetamides; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Rifampin; Tuberculosis, Multidrug-Resistant	2009
Susceptibility of clinical Mycobacterium tuberculosis isolates to a potentially less toxic derivate of linezolid, PNU-100480. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3 Topics: Acetamides; Antitubercular Agents; Ethambutol; Isoniazid; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant	2011
Linezolid safety, tolerability and efficacy to treat multidrug- and extensively drug-resistant tuberculosis. The European respiratory journal, 2011, Volume: 38, Issue:3 Topics: Acetamides; Adult; Amikacin; Antitubercular Agents; Capreomycin; Drug-Related Side Effects and Adverse Reactions; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Humans; Infectious Disease Medicine; Isoniazid; Kanamycin; Linezolid; Male; Middle Aged; Oxazolidinones; Rifampin	2011
Interactions of linezolid and second-line anti-tuberculosis agents against multidrug-resistant Mycobacterium tuberculosis in vitro and in vivo. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2016, Volume: 52 Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Capreomycin; Drug Combinations; Drug Interactions; Humans; Isoniazid; Linezolid; Male; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant	2016
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand. The European respiratory journal, 2016, Volume: 48, Issue:4 Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Clofazimine; Depression; Drug Costs; Emigrants and Immigrants; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Health Care Costs; Humans; India; Isoniazid; Linezolid; Male; Mediastinum; Microbial Sensitivity Tests; Moxifloxacin; New Zealand; Pyrazinamide; Radiography, Thoracic; Rifampin; Schizophrenia, Paranoid; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pleural; Tuberculosis, Pulmonary	2016
TB Alliance regimen development for multidrug-resistant tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, 12-01, Volume: 20, Issue:12 Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Dose-Response Relationship, Drug; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Linezolid; Moxifloxacin; Nitroimidazoles; Pyrazinamide; Randomized Controlled Trials as Topic; Research Design; Rifampin; Tuberculosis, Multidrug-Resistant	2016
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases. The European respiratory journal, 2017, Volume: 50, Issue:1 Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Isoniazid; Linezolid; Mycobacterium tuberculosis; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization	2017
Antituberculosis drug prescribing for inpatients in a national tuberculosis hospital in China, 2011-2015. Journal of global antimicrobial resistance, 2018, Volume: 14 Topics: Antitubercular Agents; China; Drug Prescriptions; Extensively Drug-Resistant Tuberculosis; Hospitals, Chronic Disease; Humans; Inpatients; Isoniazid; Linezolid; Medical Records; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Retrospective Studies; Rifampin	2018
Combinatory activity of linezolid and levofloxacin with antituberculosis drugs in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland), 2018, Volume: 111 Topics: Antitubercular Agents; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Isoniazid; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin	2018
Antituberculous drugs modulate bacterial phagolysosome avoidance and autophagy in Mycobacterium tuberculosis-infected macrophages. Tuberculosis (Edinburgh, Scotland), 2018, Volume: 111 Topics: Antitubercular Agents; Autophagy; Diarylquinolines; Host-Pathogen Interactions; Humans; Isoniazid; Linezolid; Macrophages; Mycobacterium tuberculosis; Phagosomes; Rifampin; Tuberculosis; U937 Cells	2018
Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis. Journal of basic and clinical physiology and pharmacology, 2018, Dec-19, Volume: 30, Issue:1 Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Isoniazid; Linezolid; Male; Optic Neuritis; Tuberculosis, Pulmonary	2018
Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization. PLoS medicine, 2019, Volume: 16, Issue:4 Topics: Adult; Antitubercular Agents; Decision Support Techniques; Disease Progression; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Linezolid; Lung; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tissue Distribution; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult	2019
Determination of minimum bactericidal concentration, in single or combination drugs, against Future microbiology, 2020, Volume: 15 Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Isoniazid; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Tuberculosis	2020
A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes. BMC microbiology, 2021, 06-05, Volume: 21, Issue:1 Topics: Antitubercular Agents; Automation; High-Throughput Screening Assays; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Microscopy; Mycobacterium tuberculosis; Phenotype; Rifampin; Tuberculosis	2021
Multidisciplinary management of difficult-to-treat drug resistant tuberculosis: a review of cases presented to the national consilium in Uganda. BMC pulmonary medicine, 2021, Jul-10, Volume: 21, Issue:1 Topics: Adolescent; Adult; Antitubercular Agents; Diarylquinolines; Female; Humans; Interdisciplinary Communication; Isoniazid; Linezolid; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Uganda; Young Adult	2021
Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Isoniazid; Linezolid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant	2022
A Mycobacterium tuberculosis-Infected Patient Who Could Not Tolerate Oral Intake Successfully Treated Using an Intravenous Tedizolid-Containing Regimen. The American journal of case reports, 2022, Oct-10, Volume: 23 Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Cutaneous Fistula; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Male; Meropenem; Micafungin; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Rifampin; Streptomycin; Teicoplanin; Tetrazoles; Tuberculosis	2022
Meropenem-vaborbactam restoration of first-line drug efficacy and comparison of meropenem-vaborbactam-moxifloxacin versus BPaL MDR-TB regimen. International journal of antimicrobial agents, 2023, Volume: 62, Issue:6 Topics: Antitubercular Agents; beta-Lactamase Inhibitors; Humans; Isoniazid; Linezolid; Meropenem; Moxifloxacin; Mycobacterium tuberculosis; Rifampin; Tuberculosis, Multidrug-Resistant	2023
Protein binding investigation of first-line and second-line antituberculosis drugs. International journal of antimicrobial agents, 2023, Volume: 62, Issue:6 Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Moxifloxacin; Protein Binding; Pyrazinamide; Rifampin; Tuberculosis	2023
Antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure. PloS one, 2023, Volume: 18, Issue:10 Topics: Amikacin; Antitubercular Agents; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Verapamil	2023