isoniazid and hydralazine

isoniazid has been researched along with hydralazine in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	70 (72.92)	18.7374
1990's	9 (9.38)	18.2507
2000's	10 (10.42)	29.6817
2010's	7 (7.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Coskun, E; Dizdaroglu, M; Donley, N; Jaruga, P; Lloyd, RS; McCullough, AK	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Boufadi, MY; Dufrasne, F; Furtmüller, PG; Gelbcke, M; Meyer, F; Nève, J; Obinger, C; Soubhye, J; Van Antwerpen, P; Zouaoui Boudjeltia, K	1
Drayer, DE; Reidenberg, MM	1
Gladkikh, SP; Piruzian, LA; Podymov, VK	2
Buxman, MM	1
Bach, JF; Dandavino, R	1
Schwarz, JA	1
Mumenthaler, M	1
Boman, G; Hassler, L; Sjöqvist, F; Strandberg, I	1
Alarcon-Segovia, D; Fishbein, E	1
Cohmen, G	1
Katsutani, N; Shionoya, H	2
Gershbein, LL; Rao, KC	1
Vidrio, H	1
Gatenby, PA	1
Sim, E	1
Biarese, V; Cargnino, M; Lerda, R; Lovisetto, P; Mairano, D; Marchi, L	1
Clark, DW	1
Günzler, V; Hanauske-Abel, HM; Schopf, RE; Schulte-Wissermann, H; Tschank, G	1
Jiang, M	1
Franke, G; Hüller, H; Schröder, L; Siegmund, W; Zschiesche, M	1
Messner, RP; Thomas, TJ	1
Kale, SA	1
Cush, JJ; Goldings, EA	1
Schifferli, JA	1
Beever, IA; Blair, IA; Brodie, MJ; Clare, RA; Dollery, CT; Mansilla Tinoco, R; Timbrell, JA	1
de Sèze, S; Dorfmann, H; Kahn, MF	2
Estes, D; Peltier, AP	1
Harpey, JP	1
McEwen, J	1
Losada, M; Meruane, J	1
Hovding, G	1
Maas, D	1
Eldredge, NT; Jiller, JJ; van Robertson, WB	1
Greengard, P; Quinn, GP; Reid, MB	1
Johansson, B	1
Dal Piaz, V; La Porta, E; Pinzauti, S	1
Feltkamp, TE; ten Veen, JH	1
ten Veen, JH	1
Gordon, GR; Peters, JH; Shafizadeh, AG	1
Holmes, J; Sapeika, N; Zwarenstein, H	1
Blomgren, SE	1
Galea, G; Geavlete, A	1
Alarcón-Segovia, D	1
Evans, DA	4
Cohen, SN; Steinberg, MS; Weber, WW	1
Nilsson, BS; Ripe, E	1
Cannat, A; Seligmann, M	1
Alarcón-Segovia, D; Betancourt, VM; Fishbein, E	1
Lee, SL; Peress, NS; Siegel, M	1
Skakun, NP	1
Preisig, R	1
DeSwarte, RD	1
Gill, EW; Sim, E; Sim, RB	1
Reidenberg, MM	1
Sinha, BK	1
Lovering, EG; Matsui, F; Robertson, DL	1
Curran, NM; Lovering, EG; Matsui, F; Robertson, DL; Sears, RW	1
Harmon, CE; Portanova, JP	1
Weinstein, A	1
Ahmad, RA; Rogers, HJ; Vandenburg, M; Wright, P	1
Hara, S; Kitagawa, H; Numata, Y; Satoh, T	1
Parker, CW	1
Berkenboom, G; Fontaine, J; Unger, P	1
Jiang, X; Khursigara, G; Rubin, RL	1
de los Angeles Sánchez-Salvatori, M; Ríos, C; Vidrio, H	1
Fernández, G; Vidrio, H	1
Campos, AE; Fernandez, G; Lorenzana-Jimenez, M; Medina, M; Vidrio, H	1
FROST, J; HJORTH, N	1
MALTEN, KE	1
EVANS, DA; WHITE, TA	1
MEILMAN, E; RAPOPORT, C; URIVETSKY, M	1
Medina, M; Vidrio, H	2
Del Giglio, M; Girolomoni, G; Schena, D; Vedove, CD	1
Crosti, C; Marzano, AV; Vezzoli, P	1
Akahoshi, T; Takemoto, T; Wada, T	1
Aklillu, E; Altman, RB; Boukouvala, S; Hein, DW; Klein, TE; McDonagh, EM	1

Reviews

22 review(s) available for isoniazid and hydralazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The role of complement in the aetiopathogenesis of systemic lupus erythematosus. Autoimmunity, 1991, Volume: 11, Issue:1 Topics: Antigen-Antibody Complex; Complement Pathway, Classical; Complement System Proteins; HLA Antigens; Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Major Histocompatibility Complex; Penicillamine	1991
Drug-induced immune-complex disease. Complement and inflammation, 1989, Volume: 6, Issue:2 Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Practolol; Procainamide	1989
[Drug-induced lupus]. Recenti progressi in medicina, 1985, Volume: 76, Issue:2 Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; Diagnosis, Differential; HLA Antigens; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Penicillamine; Procainamide; Sulfasalazine; T-Lymphocytes, Regulatory	1985
Genetically determined variability in acetylation and oxidation. Therapeutic implications. Drugs, 1985, Volume: 29, Issue:4 Topics: Acetylation; Anticonvulsants; Antidepressive Agents, Tricyclic; Debrisoquin; Disease; Drug Interactions; Genetic Variation; Humans; Hydralazine; Isoniazid; Oxidation-Reduction; Pharmaceutical Preparations; Phenelzine; Phenotype; Procainamide; Racial Groups; Sparteine; Sulfasalazine	1985
Drug-induced systemic lupus erythematosus. Differentiating it from the real thing. Postgraduate medicine, 1985, Feb-15, Volume: 77, Issue:3 Topics: Diagnosis, Differential; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Procainamide; Risk	1985
Drug-induced lupus: clinical spectrum and pathogenesis. The American journal of the medical sciences, 1985, Volume: 290, Issue:1 Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black People; Brain; Chlorpromazine; Female; Heart; Humans; Hydralazine; Isoniazid; Kidney; Liver; Lung; Lupus Erythematosus, Systemic; Male; Methyldopa; Muscles; Phenotype; Procainamide	1985
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus]. La Nouvelle presse medicale, 1972, Dec-09, Volume: 1, Issue:44 Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NZB; Neutrophils; Nucleic Acid Denaturation; Procainamide	1972
Antinuclear antibodies. Pathobiology annual, 1972, Volume: 2 Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Autoantigens; Cytotoxicity Tests, Immunologic; DNA; Fluorescent Antibody Technique; Humans; Hydralazine; Immune Adherence Reaction; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nephritis; Neutrophils; Nucleoproteins; Procainamide; Sjogren's Syndrome	1972
Lupus-like syndromes induced by drugs. Annals of allergy, 1974, Volume: 33, Issue:5 Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis	1974
[Generalized lupus erythematosus caused by methyl-phenyl-ethyl-hydantoin]. Revista medica de Chile, 1967, Volume: 95, Issue:7 Topics: Adult; Autoimmune Diseases; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Mephenytoin; Procainamide	1967
[Antinuclear factors. Demonstration and clinico-diagnostic significance]. Medizinische Klinik, 1969, Jul-18, Volume: 64, Issue:29 Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Chronic Disease; Dermatomyositis; Fluorescent Antibody Technique; Hepatitis; Humans; Hydantoins; Hydralazine; Isoniazid; Latex Fixation Tests; Lupus Erythematosus, Systemic; Methods; Neutrophils; Polyarteritis Nodosa; Scleroderma, Systemic; Sjogren's Syndrome; Thymus Neoplasms	1969
[Side effects of drugs. 4. Drug induced polyneuropathies and myopathies]. Lakartidningen, 1969, Dec-15, Volume: 66 Topics: Adrenocorticotropic Hormone; Chloroquine; Glucocorticoids; Humans; Hydralazine; Isoniazid; Muscular Diseases; Neurons, Afferent; Nitrofurans; Peripheral Nervous System Diseases; Thalidomide; Vincristine	1969
Drug-induced lupus syndromes. Mayo Clinic proceedings, 1969, Volume: 44, Issue:9 Topics: Antibodies, Antinuclear; Anticonvulsants; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1969
Genetic factors in drug therapy. The Scientific basis of medicine annual reviews, 1969 Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; Hydralazine; Isoniazid; Liver; Male; Myocardial Infarction; Pharmaceutical Preparations; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenytoin; Polymorphism, Genetic; Polyneuropathies; Streptomycin; Sulfamethazine; Tuberculosis, Pulmonary	1969
[Pharmacokinetics of drug preparations metabolized by N-acetyltransferase]. Klinicheskaia meditsina, 1982, Volume: 60, Issue:1 Topics: Acetylation; Acetyltransferases; Dapsone; Humans; Hydralazine; Inactivation, Metabolic; Isoniazid; Kinetics; Liver; Pharmaceutical Preparations; Phenotype; Procainamide; Sulfamethazine; Sulfasalazine	1982
Drug-induced lupus: clinical and serological studies. Clinics in rheumatic diseases, 1982, Volume: 8, Issue:1 Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cross Reactions; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Hydralazine; Hypertension; Isoniazid; Joint Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged; Pain; Pleural Effusion; Pleurisy; Procainamide; T-Lymphocytes	1982
Drug-induced systemic lupus erythematosus. Progress in clinical immunology, 1980, Volume: 4 Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1980
Drug-induced lupus erythematosus. Archives of dermatological research, 2009, Volume: 301, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antibodies; Antifungal Agents; Antihypertensive Agents; Antitubercular Agents; Arthritis; Calcium Channel Blockers; Exanthema; Humans; Hydralazine; Interferons; Isoniazid; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Naphthalenes; Procainamide; Serositis; Sodium Chloride Symporter Inhibitors; Terbinafine; Tumor Necrosis Factor-alpha	2009
Drug-induced lupus: an update on its dermatologic aspects. Lupus, 2009, Volume: 18, Issue:11 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoantibodies; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Minocycline; Procainamide; Skin Diseases	2009
[Fever induced by various drugs]. Rinsho byori. The Japanese journal of clinical pathology, 2009, Volume: Suppl 143 Topics: Amphetamine; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Body Temperature Regulation; Chlorpromazine; Contraindications; Dextromethorphan; Fever; Histamine Antagonists; Homeostasis; Humans; Hydralazine; Hypothalamus; Isoniazid; Lupus Erythematosus, Systemic; Sympathetic Nervous System	2009
PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. Pharmacogenetics and genomics, 2014, Volume: 24, Issue:8 Topics: Alleles; Arylamine N-Acetyltransferase; Caffeine; Gene Expression Profiling; Genomics; Genotype; Humans; Hydralazine; Isoenzymes; Isoniazid; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Sulfamethoxazole; Sulfasalazine; Xenobiotics	2014

Other Studies

74 other study(ies) available for isoniazid and hydralazine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1). ACS chemical biology, 2015, Oct-16, Volume: 10, Issue:10 Topics: Antineoplastic Agents; DNA Glycosylases; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrazines; Inhibitory Concentration 50; Small Molecule Libraries	2015
From Dynamic Combinatorial Chemistry to ACS medicinal chemistry letters, 2017, Feb-09, Volume: 8, Issue:2 Topics:	2017
Clinical consequences of polymorphic acetylation of basic drugs. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3 Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Pharmaceutical Preparations; Phenelzine; Phenotype; Polymorphism, Genetic; Procainamide; Sulfasalazine	1977
[Molecular aspects of disorders in fibrillogenesis of connective tissue caused by medicinal ligands]. Doklady Akademii nauk SSSR, 1979, Jun-11, Volume: 246, Issue:5 Topics: Animals; Connective Tissue; Humans; Hydralazine; Isoniazid; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase	1979
The role of enzymatic coupling of drugs to proteins in induction of drug specific antibodies. The Journal of investigative dermatology, 1979, Volume: 73, Issue:3 Topics: Animals; Antibodies; Antibody Specificity; Blood Proteins; Carrier Proteins; Drug Hypersensitivity; gamma-Glutamyltransferase; Hydralazine; Immunoenzyme Techniques; Isoniazid; Nucleoproteins; Rabbits; Skin	1979
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands]. Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:5 Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; Isoniazid; Ligands; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase	1979
[Disseminated lupus erythematosus: etiopathogenic factors]. Annales de medecine interne, 1977, Volume: 128, Issue:1 Topics: Animals; Antibodies; Autoantibodies; B-Lymphocytes; Female; Humans; Hydantoins; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Mice; Mice, Inbred NZB; Mice, Inbred Strains; Procainamide; Sunlight; T-Lymphocytes; Virus Diseases	1977
[Drug-induced disorders of lupus erythematosus type (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:96 Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Procainamide; Rats	1977
[Exotoxin-induced polyneuropathies]. Wiener medizinische Wochenschrift (1946), 1975, Apr-25, Volume: 125, Issue:17 Topics: Acrylamides; Carbon Tetrachloride Poisoning; DDT; Disulfiram; Ethanol; Humans; Hydralazine; Isoniazid; Lead Poisoning; Meprobamate; Mercury Poisoning; Methaqualone; Oxyquinoline; Polyneuropathies; Sulfur Dioxide; Thalidomide; Thallium	1975
Acetylator phenotype in patients with hydralazine-induced lupoid syndrome. Acta medica Scandinavica, 1976, Volume: 200, Issue:5 Topics: Acetylation; Administration, Oral; Adult; Age Factors; Aged; Female; Half-Life; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; Phenotype; Sex Factors; Time Factors	1976
Patterns of antinuclear antibodies and lupus-activating drugs. The Journal of rheumatology, 1975, Volume: 2, Issue:2 Topics: Antibodies, Antinuclear; Anticonvulsants; Antigens; Chlorpromazine; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Nucleoproteins; Solubility; Tuberculosis, Pulmonary	1975
[Drug-induced lupus erythematosus-like syndromes]. Medizinische Klinik, 1976, May-07, Volume: 71, Issue:19 Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydantoins; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Lymphocytes; Male; Middle Aged; Procainamide	1976
Drug-specific immune responses induced by immunization with drugs in guinea pigs and mice. The Journal of toxicological sciences, 1992, Volume: 17, Issue:4 Topics: Animals; Antibodies; Antibody Specificity; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Feasibility Studies; Female; Freund's Adjuvant; Guinea Pigs; Hydralazine; Isoniazid; Male; Mice; Mice, Inbred BALB C; Penicillin G; Rats; Rats, Sprague-Dawley	1992
Drug-specific immune responses induced by procainamide, hydralazine and isoniazid in guinea-pigs. International journal of immunopharmacology, 1992, Volume: 14, Issue:4 Topics: Animals; Antibodies; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Hydralazine; Isoniazid; Ovalbumin; Penicillins; Procainamide; Serum Albumin, Bovine	1992
Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats. Oncology research, 1992, Volume: 4, Issue:3 Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Hydralazine; Injections, Subcutaneous; Isoniazid; Male; Phenelzine; Rats; Rats, Inbred Strains	1992
Interaction with pyridoxal as a possible mechanism of hydralazine hypotension. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1 Topics: Anesthesia; Animals; Blood Pressure; Cinnarizine; Dose-Response Relationship, Drug; Hydralazine; Injections, Intraperitoneal; Isoniazid; Male; Pyridoxal; Pyridoxine; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil	1990
Effects of hydrazyl group containing drugs on leucocyte functions: an immunoregulatory model for the hydralazine-induced lupus-like syndrome. Journal of immunopharmacology, 1985, Volume: 7, Issue:4 Topics: Concanavalin A; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Leukocytes; Luminescent Measurements; Lupus Erythematosus, Systemic; Lymphocyte Activation; Models, Biological; Syndrome; Transglutaminases	1985
[Primary investigation of drug-induced lupus]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1988, Volume: 10, Issue:5 Topics: Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Phenytoin	1988
[Pharmacokinetic interactions between dihydralazine and INH in rabbits]. Die Pharmazie, 1988, Volume: 43, Issue:1 Topics: Animals; Dihydralazine; Drug Interactions; Hydralazine; Isoniazid; Rabbits	1988
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. Arthritis and rheumatism, 1986, Volume: 29, Issue:5 Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic Acid Conformation; Penicillamine; Polydeoxyribonucleotides; Procainamide	1986
Hydralazine and isoniazid reduce the formation of soluble immune complexes by complement. Immunology letters, 1985, Volume: 9, Issue:5 Topics: Antigen-Antibody Complex; Complement C3; Complement C4; Complement System Proteins; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Lupus Erythematosus, Systemic	1985
Plasma hydrazine concentrations in man after isoniazid and hydralazine administration. Human toxicology, 1985, Volume: 4, Issue:2 Topics: Acetylation; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydralazine; Hydrazines; Hypertension; Isoniazid; Male; Phenotype	1985
Letter: Aetiology of systemic lupus erythematosus. Lancet (London, England), 1974, Dec-28, Volume: 2, Issue:7896 Topics: Acetylation; Antibody Formation; DNA; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1974
Occupational dermatitis from hydrazine hydrate used in boiler protection. Cross sensitization to apresoline, isoniazid and phenelzine. Acta dermato-venereologica, 1967, Volume: 47, Issue:5 Topics: Adult; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Humans; Hydralazine; Hydrazines; Isoniazid; Male; Phenelzine; Skin Tests	1967
The interaction of lupus-inducing drugs with deoxyribonucleic acid. Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2 Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity	1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Chloramine-T as titrimetric reagent in potentiometric determination of isoniazid, phenelzine, and dihydralazine. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:9 Topics: Chloramines; Chromatography, Thin Layer; Hydralazine; Indicators and Reagents; Isoniazid; Oxidation-Reduction; Phenelzine; Potentiometry; Temperature	1974
[Iatrogenic lupus: current status of the question. I. Clinical study and main drugs responsible]. La Nouvelle presse medicale, 1972, Dec-02, Volume: 1, Issue:43 Topics: Antibodies, Antinuclear; Contraceptives, Oral; Diagnosis, Differential; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Procainamide; Sulfonamides	1972
Medical grand rounds--from the Medical College of Virginia. Drug-induced lupus erythematosus. Virginia medical monthly, 1974, Volume: 101, Issue:4 Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Disease Susceptibility; DNA; DNA, Single-Stranded; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Tuberculosis, Pulmonary	1974
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA). Clinical and experimental immunology, 1972, Volume: 11, Issue:2 Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs Test; DNA; Female; Fluorescent Antibody Technique; Genetics; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Methyldopa; Mice; Mice, Inbred Strains; Procainamide; Sex Factors	1972
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies. Clinical and experimental immunology, 1973, Volume: 15, Issue:3 Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Technique; Hydralazine; Isoniazid; Liver; Lupus Erythematosus, Systemic; Lymphocytes; Methyldopa; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscle, Smooth; Muscles; Procainamide	1973
Polymorphic acetylation of drugs in rabbits. Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:3 Topics: Acetylation; Aminobenzoates; Aminosalicylic Acids; Animals; Body Temperature; Chromatography, Thin Layer; Dapsone; Female; Genotype; Half-Life; Hydralazine; Intestine, Small; Isoniazid; Lethal Dose 50; Liver; Male; Methemoglobinemia; Phenotype; Polymorphism, Genetic; Rabbits; Structure-Activity Relationship; Sulfamethazine; Sulfanilamides; Time Factors	1973
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2 Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts	1973
Drug-induced lupus erythematosus. Seminars in hematology, 1973, Volume: 10, Issue:4 Topics: Antibodies; Cell Membrane; DNA; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Prednisone; Procainamide	1973
[Medicaments as iatrogenic factors in the onset of lupoid syndromes]. Medicina interna, 1974, Volume: 26, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Phenytoin; Procainamide	1974
Drug-induced lupus syndrome. The Medical letter on drugs and therapeutics, 1974, Apr-12, Volume: 16, Issue:8 Topics: Acetylation; Anticonvulsants; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Procainamide	1974
Purification and properties of N-acetyltransferase from mammalian liver. Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2 Topics: Aminosalicylic Acids; Aniline Compounds; Animals; Coenzyme A; Haplorhini; Humans; Hydralazine; Isoniazid; Kinetics; Liver; Rabbits; Rats; Species Specificity; Sulfamethazine; Sulfanilamides; Transferases	1968
Pulmonary infiltrations during dihydralazine treatment in a slow isoniazid-inactivator. Scandinavian journal of respiratory diseases, 1972, Volume: 53, Issue:1 Topics: Diagnosis, Differential; Half-Life; Humans; Hydralazine; Hypertension; Isoniazid; Lung; Lung Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged; Pleural Effusion; Serologic Tests; Skin Tests; Spirometry	1972
Induction by isoniazid and hydrallazine of antinuclear factors in mice. Clinical and experimental immunology, 1968, Volume: 3, Issue:1 Topics: Age Factors; Animals; Antibodies, Antinuclear; Autoantibodies; Female; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Mice; Sex Factors	1968
Antibodies to nucleoprotein and to hydrazide-altered soluble nucleoprotein in tuberculous patients receiving isoniazid. Clinical and experimental immunology, 1969, Volume: 5, Issue:4 Topics: Adult; Age Factors; Animals; Antigens; Autoantibodies; Cattle; Child; Complement Fixation Tests; DNA; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Nucleoproteins; Sex Factors; Thymus Gland; Tuberculosis	1969
Drug-induced lupus syndromes. British medical journal, 1970, Apr-25, Volume: 2, Issue:5703 Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1970
Pharmacogenetics. Transactions of the Medical Society of London, 1970, Volume: 86 Topics: Aged; Cortisone; Enzyme Induction; Female; Glaucoma; Humans; Hydralazine; Intraocular Pressure; Isoniazid; Male; Nortriptyline; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenylbutazone; Polymorphism, Genetic; Pregnancy; Sulfamethazine; Twins	1970
The epidemiology of drug-induced systemic lupus erythematosus. Arthritis and rheumatism, 1967, Volume: 10, Issue:5 Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; New York City; Phenytoin; Procainamide	1967
[Pharmacogenetics: light in the darkness of drug toxicity]. Schweizerische medizinische Wochenschrift, 1982, Jul-24, Volume: 112, Issue:30 Topics: Acetylation; Biological Availability; Drug Combinations; Glucosamine; Humans; Hydralazine; Hydroxylation; Isoniazid; Liver; Pharmacogenetics; Receptors, Drug; Sulfasalazine	1982
Drug allergy--problems and strategies. The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 1 Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Encephalomyelitis, Acute Disseminated; Exanthema; Humans; Hydralazine; Immunity, Cellular; Isoniazid; Kidney Diseases; Liver Diseases; Lupus Erythematosus, Systemic; Lymphoid Tissue; Methyldopa; Nephritis, Interstitial; Penicillins; Phenytoin; Procainamide; Respiratory Hypersensitivity; Vasculitis, Leukocytoclastic, Cutaneous	1984
Drugs that induce systemic lupus erythematosus inhibit complement component C4. Lancet (London, England), 1984, Aug-25, Volume: 2, Issue:8400 Topics: Acetylation; Complement C4; Complement Pathway, Classical; Humans; Hydralazine; Iproniazid; Isoniazid; Lupus Erythematosus, Systemic; Phenylhydrazines	1984
Complement C4 and drug-induced SLE. Lancet (London, England), 1984, Aug-25, Volume: 2, Issue:8400 Topics: Complement C4; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic	1984
The chemical induction of systemic lupus erythematosus and lupus-like illnesses. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Lymphocytes; Phenotype; Procainamide; Time Factors	1981
Enzymatic activation of hydrazine derivatives. A spin-trapping study. The Journal of biological chemistry, 1983, Jan-25, Volume: 258, Issue:2 Topics: Electron Spin Resonance Spectroscopy; Hydralazine; Hydrazines; Hydrogen-Ion Concentration; Iproniazid; Isoniazid; Phenylhydrazines	1983
Determination of hydrazine in pharmaceuticals III: hydralazine and isoniazid using GLC. Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:8 Topics: Chemistry, Pharmaceutical; Chromatography, Gas; Drug Combinations; Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Solutions; Tablets	1983
Hydrazine levels in formulations of hydralazine, isoniazid, and phenelzine over a 2-year period. Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:8 Topics: Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Phenelzine; Solutions; Tablets; Time Factors	1983
Effects of concurrent administration of other substrates of N-acetyltransferase on dapsone acetylation. British journal of clinical pharmacology, 1981, Volume: 12, Issue:1 Topics: Acetylation; Acetyltransferases; Animals; Dapsone; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Rats; Sulfamethazine	1981
Potentiation of hydralazine-induced convulsion by isoniazid in rats. Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Hydralazine; Isoniazid; Male; Rats; Seizures	1981
Hapten immunology and allergic reactions in humans. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Animals; Autoimmune Diseases; Carrier Proteins; Drug Hypersensitivity; Environmental Health; Haptens; HLA Antigens; Humans; Hydralazine; Immunization, Passive; Isoniazid; Lupus Erythematosus, Systemic; Macromolecular Substances; Methyldopa; Nitrobenzenes; Nucleic Acids; Penicillins; Procainamide	1981
Interaction between hydralazine and nitrovasodilators in vascular smooth muscle. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:3 Topics: Animals; Aorta, Thoracic; Drug Interactions; Drug Tolerance; Hydralazine; In Vitro Techniques; Isoniazid; Male; Molsidomine; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Rats; Rats, Wistar; Vasodilator Agents	1993
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils. Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186 Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydrogen Peroxide; Isoniazid; Lupus Erythematosus, Systemic; Mice; Neutrophil Activation; Neutrophils; Peroxidase; Procainamide; Propylthiouracil; Quinidine; Tumor Cells, Cultured	1994
Interaction between isoniazid and diverse vasodilators: role of decreased cerebral GABA. Cardiovascular research, 1998, Volume: 37, Issue:3 Topics: Animals; Blood Pressure; Captopril; Dipyridamole; Drug Synergism; gamma-Aminobutyric Acid; Guanidines; Heart Rate; Hydralazine; Hypothalamus; Isoniazid; Male; Minoxidil; Pinacidil; Pons; Prazosin; Rats; Rats, Wistar; Vasodilator Agents	1998
Potentiation by isoniazid of relaxation induced by nitrovasodilators in rat aorta. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:3 Topics: Animals; Aorta; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Hydralazine; Isoniazid; Male; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents	1998
Enhancement of hydralazine hypotension by low doses of isoniazid. Possible role of semicarbazide-sensitive amine oxidase inhibition. General pharmacology, 2000, Volume: 35, Issue:4 Topics: Amine Oxidase (Copper-Containing); Animals; Blood Pressure; Brain Chemistry; Drug Synergism; Enzyme Inhibitors; gamma-Aminobutyric Acid; Heart Rate; Hydralazine; In Vitro Techniques; Isoniazid; Male; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents	2000
Contact dermatitis from hydrazine hydrochloride in soldering flux; cross sensitization to apresoline and isoniazid. Acta dermato-venereologica, 1959, Volume: 39 Topics: Dermatitis, Contact; Humans; Hydralazine; Hydrazines; Isoniazid; Salts; Zinc Compounds	1959
[Contact dermatitis caused by industrial use of hydrazine derivatives with group hypersensitivity to hydralazine (Apresoline) and isoniazid (INH)]. Nederlands tijdschrift voor geneeskunde, 1962, Nov-03, Volume: 106 Topics: Dermatitis, Contact; Dermatitis, Occupational; Humans; Hydralazine; Hydrazines; Hypersensitivity; Isoniazid	1962
HUMAN ACETYLATION POLYMORPHISM. The Journal of laboratory and clinical medicine, 1964, Volume: 63 Topics: 4-Aminobenzoic Acid; Acetylation; Acyltransferases; Adenine Nucleotides; Adenosine Triphosphate; Coenzyme A; Humans; Hydralazine; Isoniazid; Liver; Metabolism; NAD; Sulfamethazine; Sulfanilamide; Sulfanilamides; Transferases; Urine	1964
ENZYMES AND DRUG SENSITIVITY. ACETYLATION POLYMORPHISMS. Proceedings of the Royal Society of Medicine, 1964, Volume: 57 Topics: Acetylation; Aminosalicylic Acid; Aminosalicylic Acids; Biomedical Research; Genetics, Medical; Hydralazine; Isoniazid; Liver; Metabolism; Monoamine Oxidase Inhibitors; Phenelzine; Toxicology	1964
CONJOINT CLINIC ON DRUGS AND GENES. Journal of chronic diseases, 1965, Volume: 18 Topics: Acetates; Aminosalicylic Acid; Aminosalicylic Acids; Coenzyme A; Diabetes Mellitus; Genetics, Medical; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Hydralazine; Insulin; Isoniazid; Kidney; Liver; Metabolism; Neuritis; Pharmacology; Phenelzine; Sulfamethazine; Toxicology	1965
THE EFFECT OF HYDRALAZINE (APRESOLINE) ON COLLAGEN SYNTHESIS IN CARRAGEENIN GRANULOMAS. Arthritis and rheumatism, 1965, Volume: 8 Topics: Carrageenan; Collagen; Granuloma; Guinea Pigs; Hydralazine; Isoniazid; Pharmacology; Phenytoin; Polysaccharides; Proteins; Research; Toxicology	1965
2-bromoethylamine, a suicide inhibitor of semicarbazide-sensitive amine oxidase, increases hydralazine hypotension in rats. Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:3 Topics: Amine Oxidase (Copper-Containing); Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ethylamines; Heart Rate; Hydralazine; Isoniazid; Male; Rats; Rats, Wistar; Semicarbazides; Verapamil	2005
Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor. Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:6 Topics: Amine Oxidase (Copper-Containing); Animals; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydralazine; Hydroxylamine; Hypotension; Injections, Intravenous; Isoniazid; Male; Methylamines; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents	2007