Compounds > isoniazid

isoniazid and cyclosporine

isoniazid has been researched along with cyclosporine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.00)18.2507
2000's5 (20.00)29.6817
2010's15 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Askari, H; Hafiz, S; Hashmi, A; Hussain, I; Hussain, M; Hussain, Z; Naqvi, SA; Rizvi, SA; Yazdani, I1
Zylber-Katz, E1
Chen, CH; Hsieh, H; Lai, MK1
Ernst, W; Gossmann, J; Kachel, HG; Peschke, B; Scheuermann, EH; Schoeppe, W1
Cho, WH; Joo, I; Kim, HC; Park, CH; Park, SB; Park, YI; Suk, J1
Garg, SK; Gupta, KL; Jha, V; Kohli, HS; Muthukumar, T; Sakhuja, V; Singh, B; Sud, K1
de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA1
Eguchi, K; Ida, H; Imanishi, D; Kawakami, A; Motomura, M; Nakamura, H; Okada, A; Yamasaki, S1
D'Addio, SM; Einck, L; Liu, Y; Prud'homme, RK; Reddy, VM; Sinko, PJ1
Fujita, T; Fukushima, N; Fukushima, S; Kobayashi, J; Kumai, Y; Kuroda, K; Matsuda, S; Matsumoto, Y; Nakajima, S; Seguchi, O; Shionoiri, A; Wada, K; Wakamiya, A; Yanase, M1

Reviews

1 review(s) available for isoniazid and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for isoniazid and cyclosporine

ArticleYear
Isoniazid does not affect bioavailability of cyclosporine in renal transplant recipients.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8

    Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Antitubercular Agents; Area Under Curve; Biological Availability; Cyclosporine; Drug Interactions; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Metabolic Clearance Rate; Middle Aged; Tuberculosis

2000

Other Studies

23 other study(ies) available for isoniazid and cyclosporine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Is there a place for prophylaxis against tuberculosis following renal transplantation?
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Child; Cyclosporine; Female; Follow-Up Studies; Humans; Isoniazid; Kidney Transplantation; Male; Retrospective Studies; Steroids; Tuberculosis

1992
Multiple drug interactions with cyclosporine in a heart transplant patient.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:2

    Topics: Cyclosporine; Drug Interactions; Drug Monitoring; Erythromycin; Heart Transplantation; Humans; Immunosuppression Therapy; Isoniazid; Male; Middle Aged; Rifampin

1995
Pulmonary tuberculosis or MOTT infection in kidney transplant recipients.
    Transplantation proceedings, 1994, Volume: 26, Issue:4

    Topics: Adult; Cyclosporine; Ethambutol; Humans; Isoniazid; Kidney Transplantation; Mycobacterium Infections; Prednisolone; Streptomycin; Tuberculosis, Pulmonary

1994
Antituberculous drugs in kidney transplant recipients treated with cyclosporine.
    Transplantation, 1993, Volume: 56, Issue:1

    Topics: Aged; Antitubercular Agents; Cyclosporine; Drug Interactions; Ethambutol; Humans; Isoniazid; Kidney Transplantation; Male; Middle Aged; Rifampin; Tuberculosis, Pulmonary

1993
Clinical manifestations of tuberculosis in renal transplant patients.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Adult; Antitubercular Agents; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Incidence; Isoniazid; Kidney Transplantation; Male; Middle Aged; Mycobacterium tuberculosis; Polymerase Chain Reaction; Postoperative Complications; Retrospective Studies; Time Factors; Tuberculosis; Tuberculosis, Pulmonary

1996
Tuberculosis in a patient on temozolomide: a case report.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary

2009
Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.
    Rheumatology international, 2010, Volume: 30, Issue:12

    Topics: Antitubercular Agents; Cyclosporine; Drug Therapy, Combination; Erythroblasts; Female; Humans; Immunosuppressive Agents; Iron; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Myasthenia Gravis; Red-Cell Aplasia, Pure; Reticulocyte Count; Reticulocytes; Treatment Outcome

2010
Antitubercular Nanocarrier Combination Therapy: Formulation Strategies and in Vitro Efficacy for Rifampicin and SQ641.
    Molecular pharmaceutics, 2015, May-04, Volume: 12, Issue:5

    Topics: Antitubercular Agents; Cyclosporine; Isoniazid; Macrophages; Mycobacterium tuberculosis; Nanoparticles; Rifampin; Vitamin E

2015
Paradoxical Reaction of Tuberculosis in a Heart Transplant Recipient During Antituberculosis Therapy: A Case Report.
    Transplantation proceedings, 2018, Volume: 50, Issue:3

    Topics: Antitubercular Agents; Cyclosporine; Heart Transplantation; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoniazid; Male; Middle Aged; Postoperative Complications; Tuberculosis, Miliary

2018