Compounds > isoniazid

isoniazid and btz 043

isoniazid has been researched along with btz 043 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (95.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Baulard, AR; Crauste, C; Déprez, B; Flipo, M; Villemagne, B; Willand, N1
Alling, T; Bailey, M; Boshoff, H; Cramer, J; Hipskind, PA; Markley, LD; Miller, MJ; Moraski, GC; Ollinger, J; Parish, T1
Ambady, A; Guptha, S; Hegde, N; Hosagrahara, VP; Humnabadkar, V; Kaur, P; Mahadevaswamy, J; Nagalapur, K; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, S; Ramachandran, V; Rudrapatna, SS; Sambandamurthy, VK; Sharma, S; Shirude, PS1
Achar, V; Ambady, A; Awasthy, D; Bathula, C; Binda, C; Chatterji, M; Chiarelli, LR; Dhar, N; Dinesh, N; Ghorpade, SR; Gorai, G; Guptha, S; Hegde, N; Hosagrahara, V; Humnabadkar, V; Iyer, PS; Jatheendranath, S; Jena, LK; Kaur, P; Kavanagh, S; Koushik, K; Madhavapeddi, P; Mahadevaswamy, J; Manjrekar, P; Manjunatha, MR; McKinney, JD; McLaughlin, B; Naik, M; Narayan, A; Narayan, C; Narayanan, S; Neres, J; Panda, M; Panduga, V; Pasca, MR; Prabhakar, K; Ramachandran, V; Ravishankar, S; Reddy, J; Riccardi, G; Rudrapatna, S; Sambandamurthy, VK; Saralaya, R; Shanbhag, G; Shandil, R; Sharma, S; Signorino-Gelo, F; Tantry, SJ; Tommasi, R; Whiteaker, J1
Ambady, A; Butler, S; Chatterji, M; Cooper, CB; Humnabadkar, V; Iyer, PS; Jena, LK; Manjunatha, MR; McLaughlin, RE; Mdluli, K; Nanduri, R; Narayanan, S; Panda, M; Panduga, V; Prabhakar, KR; Ravishankar, S; Reddy, J; Sadler, C; Sambandamurthy, VK; Saralaya, R; Shandil, RK; Sharma, S; Shirude, PS; Srivastava, A; Suresh, RS; Whiteaker, J1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P1
Biava, M; Cocozza, M; Consalvi, S; Poce, G1
Cho, S; Franzblau, SG; Miller, MJ; Miller, PA; Tiwari, R1
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J1
Arkile, MA; Asgaonkar, KD; Chitre, TS; Dharme, AB; Jha, PC; Khedkar, VM; Miniyar, PB; Sarkar, D; Yeware, A1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K1
Barmade, MA; Chikhale, RV; Murumkar, PR; Yadav, MR1
Batt, SM; Besra, GS; Huang, H; Li, G; Li, P; Lin, Z; Lu, Y; Ma, C; Wang, B; Zhang, D; Zhang, T; Zhang, X1
Argyrou, A; Augustyns, K; Balabon, O; Ballell, L; Barros, D; Bates, RH; Blanco-Ruano, D; Cacho, M; Cunningham, F; Huss, S; Lopez-Roman, EM; Pitta, E; Rogacki, MK; Van der Veken, P; Vande Velde, CML1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K1
Ambady, A; Butler, S; Chatterji, M; Cooper, C; Guptha, S; Iyer, PS; Kumar, N; Mahadevaswamy, J; Mallya, M; Mdluli, K; Narayan, A; Narayanan, S; Panda, M; Panduga, V; R, MM; Ramachandran, V; Sadler, C; Sambandamurthy, VK; Shandil, R; Sharma, S; Shirude, PS; Sreenivasaiah, M; Tommasi, R1
Castagnolo, D; Denny, WA; Dos Santos, JL; Fernandes, GFS; Thompson, AM1
Gao, C; Peng, CT; Wang, NY; Wei, Y; Xia, Y; Xiong, Y; Xu, Y; Ye, TH; You, XY; Yu, LT; Zeng, XX; Zhang, LD; Zuo, WQ1
Alam, MS; Kalia, NP; Khan, IA; Mir, F; Mulakayala, C; Mulakayala, N; Rajput, VS; Shafi, S; Zaman, MS1
Balakrishnan, G; Bhat, J; Chatterji, M; Dinesh, N; Ghorpade, S; Gorai, G; Guptha, S; Humnabadkar, V; Iyer, PS; Jena, LK; Kaur, P; Khadtare, P; Naik, M; Nandishaiah, R; Narayan, A; Naviri, LK; Panda, M; Ramachandran, V; Sharma, S1

Reviews

3 review(s) available for isoniazid and btz 043

ArticleYear
Tuberculosis: the drug development pipeline at a glance.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Drug Discovery; Humans; Tuberculosis

2012
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Animals; Antitubercular Agents; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant

2014
Tuberculosis Drug Discovery: Challenges and New Horizons.
    Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11

    Topics: Antitubercular Agents; COVID-19 Drug Treatment; Drug Discovery; Humans; Mycobacterium tuberculosis; Tuberculosis

2022

Other Studies

17 other study(ies) available for isoniazid and btz 043

ArticleYear
Advancement of Imidazo[1,2-
    ACS medicinal chemistry letters, 2013, Jul-11, Volume: 4, Issue:7

    Topics:

2013
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pyrazoles; Pyridones; Structure-Activity Relationship

2014
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Alcohol Oxidoreductases; Amides; Animals; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Cell Line, Tumor; Drug Resistance, Bacterial; Genome, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Piperidines; Protein Binding; Quinolones; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship

2014
Lead optimization of 1,4-azaindoles as antimycobacterial agents.
    Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13

    Topics: Alcohol Oxidoreductases; Animals; Antitubercular Agents; Bacterial Proteins; Cyclic Nucleotide Phosphodiesterases, Type 6; Disease Models, Animal; Humans; Indoles; Mice; Mycobacterium tuberculosis; Oxidoreductases; Rats; Structure-Activity Relationship

2014
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043.
    ACS medicinal chemistry letters, 2015, Feb-12, Volume: 6, Issue:2

    Topics:

2015
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles

2016
Synthesis and docking studies of pyrazine-thiazolidinone hybrid scaffold targeting dormant tuberculosis.
    Bioorganic & medicinal chemistry letters, 2016, May-01, Volume: 26, Issue:9

    Topics: Antitubercular Agents; Molecular Docking Simulation; Pyrazines; Thiazolidines

2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles

2017
Overview of the Development of DprE1 Inhibitors for Combating the Menace of Tuberculosis.
    Journal of medicinal chemistry, 2018, 10-11, Volume: 61, Issue:19

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Drug Development; Humans; Mycobacterium tuberculosis; Tuberculosis

2018
Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.
    European journal of medicinal chemistry, 2018, Dec-05, Volume: 160

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Dose-Response Relationship, Drug; Female; HEK293 Cells; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazines; Vero Cells

2018
Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors.
    Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24

    Topics: Actinobacteria; Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Drug Stability; Enzyme Inhibitors; Hep G2 Cells; High-Throughput Screening Assays; Humans; Hydantoins; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Reproducibility of Results; Structure-Activity Relationship; Tuberculosis

2018
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles

2019
Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity.
    ACS medicinal chemistry letters, 2019, Oct-10, Volume: 10, Issue:10

    Topics:

2019
Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Humans; Mycobacterium tuberculosis; Rats; Rats, Sprague-Dawley; Spiro Compounds; Structure-Activity Relationship; Thiazines; Tuberculosis; Vero Cells

2013
Sulfur rich 2-mercaptobenzothiazole and 1,2,3-triazole conjugates as novel antitubercular agents.
    European journal of medicinal chemistry, 2014, Apr-09, Volume: 76

    Topics: Antitubercular Agents; Benzothiazoles; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Spectrometry, Mass, Electrospray Ionization; Sulfur

2014
2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.
    ACS medicinal chemistry letters, 2014, Sep-11, Volume: 5, Issue:9

    Topics:

2014
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