isoniazid and azathioprine

isoniazid has been researched along with azathioprine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199015 (44.12)18.7374
1990's1 (2.94)18.2507
2000's4 (11.76)29.6817
2010's13 (38.24)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Knoblauch, M1
Buselmaier, W; Herbold, B1
Kvapilová, M; Mison, P; Trnka, L1
Bellendir, EN; Nakonechnyĭ, GD; Peschanskaia, IN; Salmagambetov, IU1
Bloedner, CD1
Askari, H; Hafiz, S; Hashmi, A; Hussain, I; Hussain, M; Hussain, Z; Naqvi, SA; Rizvi, SA; Yazdani, I1
Hudgel, DW; Neff, TA1
Lakshiminarayan, S; Sahn, SA1
Houde, M; Laplante, L1
Falcao, H; Galdabini, J; Gould, DB1
Gaines, JD; Griepp, RB; Remington, JS; Shumway, NE1
Campbell, GS; Flanigan, WJ; Williams, GD1
Dormont, J; Schwarzenberg, L1
Carey, TB; Goltz, RW; Park, RK1
Bueno, R; Celma, ML; Jiménez del Cerro, L; Marcén, R; Matesanz, R; Ortuño, J; Quereda, C; Teruel, JL1
Kern, F; Mallory, A1
Fisch, P; Handgretinger, R; Schaefer, HE1
Chan, TM; Lau, CS; Lo, Y; Mok, MY; Wong, WS1
Dolianitis, C; Howard, A; Rudd, A; Varigos, G1
Franzen, D; Greutmann, M; Kolios, A; Liebscher, F; Pfammatter, T1
Borekci, S; Celik, AF; Esatoglu, SN; Fresko, I; Hacioglu, A; Hamuryudan, V; Hatemi, G; Hatemi, I; Melikoglu, M; Ongen, HG; Ozdogan, H; Ozguler, Y; Seyahi, E; Ugurlu, S; Yurdakul, S1

Reviews

4 review(s) available for isoniazid and azathioprine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Drug induced liver disease (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9

    Topics: Azathioprine; Bile Acids and Salts; Bilirubin; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Collagen; Contraceptives, Oral, Hormonal; Enzyme Induction; Female; Humans; Isoniazid; Male; Pharmaceutical Preparations

1978
Drug-induced pancreatitis: a critical review.
    Gastroenterology, 1980, Volume: 78, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Cholestyramine Resin; Cimetidine; Cyproheptadine; Dextropropoxyphene; Diazoxide; Diuretics; Estrogens; Ethacrynic Acid; Furosemide; Histamine; Humans; Hypercalcemia; Indomethacin; Isoniazid; Mercaptopurine; Narcotics; Pancreatitis; Phenformin; Procainamide; Rifampin; Salicylates; Sodium Chloride Symporter Inhibitors; Sulfonamides; Tetracycline

1980
Pure red cell aplasia.
    British journal of haematology, 2000, Volume: 111, Issue:4

    Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Azathioprine; Bone Marrow Cells; Fanconi Anemia; Female; Humans; Immunosuppressive Agents; Infant; Isoniazid; Killer Cells, Natural; Leukemia, Lymphoid; Male; Parvovirus B19, Human; Phenytoin; Pregnancy; Pregnancy Complications, Hematologic; Red-Cell Aplasia, Pure; T-Lymphocytes

2000

Other Studies

30 other study(ies) available for isoniazid and azathioprine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Induction of point mutations by different chemical mechanisms in the liver microsomal assay.
    Mutation research, 1976, Volume: 40, Issue:2

    Topics: Animals; Azathioprine; Biotransformation; Captan; Cyclophosphamide; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Genetic Code; Hydrazines; Isoniazid; Male; Mercaptopurine; Methotrexate; Methylnitronitrosoguanidine; Mice; Microsomes, Liver; Mutagens; Protein Biosynthesis; Salmonella typhimurium

1976
Influence of immunosuppression on the action of antimycobacterial drugs in experimental tuberculosis. I. Effects of isoniazid, rifampicin and streptomycin on the survival of tuberculous mice immunosuppressed by azathioprine (Imuran).
    Chemotherapy, 1976, Volume: 22, Issue:6

    Topics: Animals; Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Immunosuppression Therapy; Isoniazid; Mice; Rifampin; Streptomycin; Tuberculosis, Pulmonary

1976
[Effect of several immunoactive agents on the course of kidney tuberculosis].
    Problemy tuberkuleza, 1976, Issue:12

    Topics: Animals; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Etimizol; Imidazoles; Isoniazid; Rabbits; Tuberculosis, Renal; Uracil

1976
[Therapy of pulmonary sarcoidosis].
    Deutsche medizinische Wochenschrift (1946), 1976, Jan-16, Volume: 101, Issue:3

    Topics: Acute Disease; Azathioprine; Chronic Disease; Humans; Isoniazid; Lung Diseases; Prednisone; Sarcoidosis

1976
Is there a place for prophylaxis against tuberculosis following renal transplantation?
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Child; Cyclosporine; Female; Follow-Up Studies; Humans; Isoniazid; Kidney Transplantation; Male; Retrospective Studies; Steroids; Tuberculosis

1992
Miliary tuberculosis in a renal transplant recipient.
    The American review of respiratory disease, 1973, Volume: 108, Issue:3

    Topics: Adult; Azathioprine; Drug Resistance, Microbial; Humans; Immunosuppression Therapy; Isoniazid; Kidney Transplantation; Male; Mycobacterium tuberculosis; Prednisone; Transplantation, Homologous; Tuberculosis, Miliary

1973
Tuberculosis in a patient after renal transplantation.
    Tubercle, 1973, Volume: 54, Issue:1

    Topics: Adult; Azathioprine; Bacteriuria; Ethambutol; Humans; Isoniazid; Kidney Transplantation; Male; Mycobacterium tuberculosis; Postoperative Complications; Prednisone; Rifampin; Sputum; Transplantation, Homologous; Tuberculin Test; Tuberculosis, Pulmonary

1973
[Meningitis due to Listeria monocytogenes. Presentation of a case and literature review].
    L'union medicale du Canada, 1973, Volume: 103, Issue:8

    Topics: Adult; Amphotericin B; Ampicillin; Azathioprine; Cephaloridine; Cyclophosphamide; Female; Humans; Isoniazid; Listeria monocytogenes; Lupus Erythematosus, Systemic; Meningitis, Listeria; Prednisone; Streptomycin

1973
Letter: Isoniazid hepatotoxicity.
    Annals of internal medicine, 1973, Volume: 79, Issue:6

    Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Glomerulonephritis; Humans; Isoniazid; Kidney Transplantation; Liver; Male; Transplantation, Homologous; Tuberculosis

1973
Further experience with infection after cardiac transplantation.
    Transplantation proceedings, 1972, Volume: 4, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Antilymphocyte Serum; Azathioprine; Cyclophosphamide; Echocardiography; Electrocardiography; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppression Therapy; Infection Control; Infections; Isoniazid; Lung Diseases; Male; Methylprednisolone; Middle Aged; Nystatin; Positive-Pressure Respiration; Radiography, Thoracic; Skin Tests; Tuberculin Test; Urinary Tract Infections; Ventilators, Mechanical

1972
Surgical management of localized thoracic infections in immunosuppressed patients.
    The Annals of thoracic surgery, 1971, Volume: 12, Issue:5

    Topics: Adult; Aspergillosis; Azathioprine; Coccidioidomycosis; Corynebacterium Infections; Female; Glomerulonephritis; Graft Rejection; Histoplasmosis; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Lung Diseases, Fungal; Male; Nephritis; Postoperative Complications; Prednisone; Transplantation, Homologous

1971
[Immunosuppressive treatment for heterologous cardiac transplantation. Its possible efficacy in a rejection crisis].
    Archives des maladies du coeur et des vaisseaux, 1969, Volume: 62, Issue:6

    Topics: Animals; Azathioprine; Betamethasone; Dexamethasone; Glucocorticoids; Graft Rejection; Heart Transplantation; Histocompatibility; Horses; Humans; Hydrocortisone; Isoniazid; Prednisolone; Serum Globulins; Sheep; Thrombocytopenia; Transplantation Immunology; Transplantation, Homologous; Tuberculosis, Pulmonary

1969
Unusual cutaneous infections associated with immunosuppressive therapy.
    Archives of dermatology, 1967, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Azathioprine; Chickenpox; Child; Female; Herpes Simplex; Histoplasmosis; Humans; Immunosuppressive Agents; Isoniazid; Kidneys, Artificial; Male; Oxacillin; Prednisone; Skin Diseases; Transplantation, Homologous

1967
[Hepatopathy in kidney transplant patients: incidence, etiology and clinical forms of presentation].
    Medicina clinica, 1984, May-12, Volume: 82, Issue:18

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cytomegalovirus Infections; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Liver Diseases; Postoperative Complications

1984
Tuberculosis in systemic lupus erythematosus in an endemic area and the role of isoniazid prophylaxis during corticosteroid therapy.
    The Journal of rheumatology, 2005, Volume: 32, Issue:4

    Topics: Adult; Antibiotic Prophylaxis; Antitubercular Agents; Azathioprine; Endemic Diseases; Female; Glucocorticoids; Hong Kong; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; Mycobacterium tuberculosis; Prednisolone; Recurrence; Tuberculosis

2005
A case of multicentric reticulohistiocytosis responsive to azathioprine in a patient with no underlying malignancy.
    The Australasian journal of dermatology, 2011, Volume: 52, Issue:4

    Topics: Antitubercular Agents; Azathioprine; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Isoniazid; Latent Tuberculosis; Male; Middle Aged; Recurrence

2011
Takayasu's Arteritis with Isolated Pulmonary Artery Involvement in a Middle-Aged Asian Woman with Hepatitis B and Latent Tuberculosis Infection.
    Respiration; international review of thoracic diseases, 2017, Volume: 93, Issue:3

    Topics: Angiography, Digital Subtraction; Antitubercular Agents; Antiviral Agents; Azathioprine; Female; Fluorodeoxyglucose F18; Glucocorticoids; Guanine; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Isoniazid; Latent Tuberculosis; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Positron-Emission Tomography; Pulmonary Artery; Radiopharmaceuticals; Recurrence; Stenosis, Pulmonary Artery; Takayasu Arteritis

2017
Screening for latent tuberculosis before starting TNF-alpha inhibitors in a population with high BCG vaccination rates.
    Rheumatology international, 2022, Volume: 42, Issue:8

    Topics: Adult; Azathioprine; BCG Vaccine; Humans; Isoniazid; Latent Tuberculosis; Male; Prednisolone; Reproducibility of Results; Tuberculin Test; Tumor Necrosis Factor Inhibitors; Vaccination

2022