isoniazid has been researched along with acetylcysteine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Lathan, SR; McLean, RL; Ramirez, J; Williams, JD | 1 |
| Ramirez, J | 2 |
| Heathcote, J; Wanless, IR | 1 |
| Attri, S; Goel, RC; Katyal, R; Nain, CK; Rana, SV; Singh, K; Sodhi, CP; Vaiphei, K | 1 |
| Attri, S; Kanwar, S; Katyal, R; Rana, SV; Singh, K; Sodhi, CP; Vaiphie, K | 1 |
| Jankowska, R; Krecicki, T; Skrzydlewska-Kaczmarek, B; Zalesska-Krecicka, M; Zatonski, T | 1 |
| Meng, Q; Shen, C; Zhang, G; Zhang, H | 1 |
| Aerry, R; Coleman, MD; Khan, NB; Lambert, PA; Rathbone, DL; Wanogho, E | 1 |
| Baniasadi, S; Eftekhari, P; Fahimi, F; Masjedi, MR; Raoufy, MR; Tabarsi, P; Velayati, AA | 1 |
| Amarapurkar, DN; Gupta, VH; Rai, G; Sasi, P; Singh, M; Wangikar, PP | 1 |
| Babaei, H; Eghbal, MA; Heidari, R | 1 |
| Amani, A; Fazly Bazzaz, BS; Khameneh, B; Rostami, J; Vahdati-Mashhadian, N | 1 |
| Kishida, K; Maeda, S; Miwa, Y; Sasabe, T; Sugiyama, T; Yamano, M | 1 |
| Jacobs, WR; Vilchèze, C | 1 |
3 review(s) available for isoniazid and acetylcysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Hepatotoxicity: newer aspects of pathogenesis and treatment.
Topics: Acetaminophen; Acetylcysteine; Adenoma, Liver Cell; Adult; Amoxicillin; Anabolic Agents; Beverages; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Contraceptives, Oral; Female; Humans; Isoniazid; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Male; Nonprescription Drugs; Propylthiouracil; Rifampin | 1995 |
The Isoniazid Paradigm of Killing, Resistance, and Persistence in Mycobacterium tuberculosis.
Topics: Acetylcysteine; Animals; Ascorbic Acid; Bacterial Proteins; Catalase; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy; Gene Transfer, Horizontal; Humans; Isoniazid; Mycobacteriophages; Mycobacterium tuberculosis; Oxidoreductases; Tuberculosis | 2019 |
1 trial(s) available for isoniazid and acetylcysteine
| Article | Year |
|---|---|
Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Free Radical Scavengers; Humans; Isoniazid; Liver; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2010 |
19 other study(ies) available for isoniazid and acetylcysteine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Pulmonary alveolar proteinosis. Treatment of a case complicated by tuberculosis.
Topics: Acetylcysteine; Adult; Aminosalicylic Acids; Female; Heparin; Humans; Isoniazid; Oxygen; Oxygen Inhalation Therapy; Pulmonary Alveolar Proteinosis; Remission, Spontaneous; Streptomycin; Therapeutic Irrigation; Tuberculosis, Pulmonary | 1971 |
Alveolar proteinosis: importance of pulmonary lavage.
Topics: Acetylcysteine; Adult; Aerosols; Heparin; Humans; Hypoxia; Isoniazid; L-Lactate Dehydrogenase; Male; Middle Aged; Oxygen; Prednisone; Pulmonary Alveolar Proteinosis; Radiography; Therapeutic Irrigation; Trypsin | 1971 |
Pulmonary alveolar proteinosis. Treatment in a case complicated by tuberculosis.
Topics: Acetylcysteine; Aminosalicylic Acids; Cycloserine; Ethionamide; Heparin; Humans; Isoniazid; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Pulmonary Alveolar Proteinosis; Pyrazinamide; Radiography, Thoracic; Respiratory Function Tests; Therapeutic Irrigation; Tuberculosis, Pulmonary | 1967 |
Isoniazid- and rifampicin-induced oxidative hepatic injury--protection by N-acetylcysteine.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Injections, Intraperitoneal; Isoniazid; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Rifampin; Superoxide Dismutase | 2000 |
Protective effect of N-acetylcysteine in isoniazid induced hepatic injury in growing rats.
Topics: Acetylcysteine; Animals; Antioxidants; Free Radical Scavengers; Glutathione; Isoniazid; Liver; Male; Oxidants; Rats; Rats, Wistar | 2001 |
Laryngeal tuberculosis.
Topics: Acetylcysteine; Adult; Antitubercular Agents; Epiglottis; Ethambutol; Female; Granuloma, Laryngeal; Humans; Isoniazid; Mycobacterium; Rifampin; Tuberculosis, Laryngeal | 2004 |
Isoniazid-induced hepatotoxicity in rat hepatocytes of gel entrapment culture.
Topics: Acetylcysteine; Animals; Antidotes; Antitubercular Agents; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Ditiocarb; Female; Glutathione; Glycyrrhiza; Glycyrrhizic Acid; Hepatocytes; Isoniazid; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin | 2006 |
Effects of glutathione and N-acetyl cysteine on the antimycobacterial efficacy of isoniazid on Mycobacterium fortuitum in vitro.
Topics: Acetylcysteine; Antioxidants; Drug Interactions; Glutathione; Isoniazid; Microbial Sensitivity Tests; Mycobacterium fortuitum; Sulfhydryl Compounds; Thioctic Acid | 2006 |
Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model.
Topics: Acetylcysteine; Antitubercular Agents; Cell Cycle; Cell Survival; Chemical and Drug Induced Liver Injury; Curcumin; Hep G2 Cells; Humans; Isoniazid; Membrane Potential, Mitochondrial; Protective Agents; Pyrazinamide; Silymarin | 2012 |
Cytoprotective effects of taurine against toxicity induced by isoniazid and hydrazine in isolated rat hepatocytes.
Topics: Acetylcysteine; Animals; Cytoprotection; Hepatocytes; Hydrazines; In Vitro Techniques; Isoniazid; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Taurine | 2013 |
Combination of anti-tuberculosis drugs with vitamin C or NAC against different Staphylococcus aureus and Mycobacterium tuberculosis strains.
Topics: Acetylcysteine; Antitubercular Agents; Ascorbic Acid; Drug Synergism; Drug Therapy, Combination; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Tuberculosis | 2016 |
The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells.
Topics: Acetylcysteine; beta-Naphthoflavone; Carbonic Anhydrase Inhibitors; Cell Line; Chromatography, High Pressure Liquid; Cysteine; Cytochrome P-450 Enzyme System; Dexamethasone; Glaucoma; Glucuronides; Humans; Isoniazid; Keratinocytes; Lyases; Methazolamide; Methimazole; Oxidation-Reduction; Oxygenases; Stevens-Johnson Syndrome; Sulfenic Acids; Sulfonic Acids; Tandem Mass Spectrometry | 2017 |