isoniazid and 3-methylcholanthrene

isoniazid has been researched along with 3-methylcholanthrene in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's3 (17.65)18.2507
2000's4 (23.53)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Bishai, WR; Guo, H; Kozikowski, AP; Lun, S; Merenbloom, B; Onajole, OK; Stec, J; Vistoli, G1
Connor, TH; Forti, GC; Legator, MS; Sitra, P1
Gillette, JR; Mitchell, JR; Snodgrass, WR1
Gelboin, HV; Huang, Q; Ji, C; Mirvish, SS; Park, SS; Wang, S1
Dich, J; Grunnet, N; Vind, C1
Gregus, Z; Klaassen, CD; Madhu, C1
Chung, EB; Rapp, HJ; Zbar, B1
Inoue, S; Singer, M1
Aniya, Y; Naito, A; Shimoji, M1
Jacqueson, A; Nicod, L; Regnier, A; Richert, L; Viollon, C1
Hurh, E; Kim, S; Kim, Y; Lee, A; Lee, E; Lee, M1
ARFFMANN, E1
Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ1
Lee, JH; Lee, MG; Yang, KH1
Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH1
CHALKLEY, HW; DANIEL, GE1

Other Studies

17 other study(ies) available for isoniazid and 3-methylcholanthrene

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection.
    Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Disease Models, Animal; Drug Design; Female; Humans; Indoles; Membrane Transport Proteins; Mice, Inbred BALB C; Microbial Sensitivity Tests; Models, Molecular; Molecular Docking Simulation; Molecular Targeted Therapy; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant

2016
Bile as a source of mutagenic metabolites produced in vivo and detected by Salmonella typhimurium.
    Environmental mutagenesis, 1979, Volume: 1, Issue:3

    Topics: Acetaminophen; Animals; Bile; Biotransformation; Cyclophosphamide; Diethylstilbestrol; Dimethylnitrosamine; Ethylene Dichlorides; Hycanthone; Isoniazid; Male; Methyl Methanesulfonate; Methylcholanthrene; Mutagens; Rats; Salmonella typhimurium; Serum Albumin, Bovine

1979
The role of biotransformation in chemical-induced liver injury.
    Environmental health perspectives, 1976, Volume: 15

    Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cricetinae; Furosemide; Glutathione; Guinea Pigs; Humans; In Vitro Techniques; Iproniazid; Isoniazid; Liver Diseases; Methylcholanthrene; Mice; Phenobarbital; Rats

1976
Positional specificity for methyl-n-amylnitrosamine hydroxylation by cytochrome P-450 isozymes determined with monoclonal antibodies.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aroclors; Carcinogens; Cytochrome P-450 Enzyme System; Hydroxylation; Isoenzymes; Isoniazid; Liver; Male; Methylcholanthrene; Microsomes; Nitrosamines; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Sex Factors; Substrate Specificity

1991
Effects of cytochrome P450-inducing agents on the monooxygenation of testosterone in long-term cultures of hepatocytes from male and female rats.
    Archives of biochemistry and biophysics, 1989, Nov-15, Volume: 275, Issue:1

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Glucagon; Hydroxylation; Insulin; Isoniazid; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Species Specificity; Steroid 16-alpha-Hydroxylase; Testosterone

1989
Inducibility of glutathione S-transferases in hamsters.
    Cancer letters, 1989, Volume: 44, Issue:2

    Topics: Animals; Butylated Hydroxyanisole; Cats; Cricetinae; Dexamethasone; Dogs; Enzyme Induction; Ethanol; Glutathione Transferase; Guinea Pigs; Isoniazid; Liver; Male; Mesocricetus; Methylcholanthrene; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Quail; Rabbits; Rats; Species Specificity; Stilbenes; Trout

1989
Tumor regression mediated by Mycobacterium bovis (strain BCG). Effects of isonicotinic acid hydrazide, cortisone acetate, and antithymocyte serum.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:1

    Topics: Animals; Antibodies, Bacterial; Antilymphocyte Serum; Cortisone; Hypersensitivity, Delayed; Isoniazid; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Mycobacterium bovis; Neoplasm Transplantation; Remission, Spontaneous; Sarcoma, Experimental; T-Lymphocytes; Time Factors; Transplantation, Homologous; Tuberculin Test

1973
Experiments on a spontaneously orginated visceral tumor in the newt, Triturus pyrrhogaster.
    Annals of the New York Academy of Sciences, 1970, Oct-30, Volume: 174, Issue:2

    Topics: Animals; Anura; Autoradiography; Cytoplasm; Gastrointestinal Neoplasms; Isoniazid; Liver; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Methylcholanthrene; Mycobacterium; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Organoids; Spleen; Streptomycin; Transplantation, Heterologous; Transplantation, Homologous; Urodela

1970
Increase in liver microsomal glutathione S-transferase activity by phenobarbital treatment of rats. Possible involvement of oxidative activation via cytochrome P450.
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Amitrole; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Ethylmaleimide; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Isoniazid; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley

1993
Rifampicin and isoniazid increase acetaminophen and isoniazid cytotoxicity in human HepG2 hepatoma cells.
    Human & experimental toxicology, 1997, Volume: 16, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitubercular Agents; Carcinoma, Hepatocellular; Cell Survival; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Humans; Isoniazid; Liver Neoplasms; Methylcholanthrene; Rifampin; Tumor Cells, Cultured

1997
Effects of enzyme inducers or inhibitors on the pharmacokinetics of intravenous parathion in rats.
    Biopharmaceutics & drug disposition, 2000, Volume: 21, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Insecticides; Isoenzymes; Isoniazid; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Paraoxon; Parathion; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Tissue Distribution

2000
STUDIES ON THE NEWT TEST FOR CARCINOGENICITY. 4. SUPPLEMENTARY EXPERIMENTS ON SPECIFICITY.
    Acta pathologica et microbiologica Scandinavica, 1964, Volume: 60

    Topics: Animals; Anthracenes; Arsenic; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Hydrocarbons; Isoniazid; Methylcholanthrene; Nitrosamines; Nitroso Compounds; Pathology; Phenanthrenes; Research; Salamandridae; Skin Neoplasms; Toxicology; Urodela

1964
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes

2005
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1

    Topics: Animals; Area Under Curve; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activators; Half-Life; Infusions, Intravenous; Isoniazid; Metabolic Clearance Rate; Methylcholanthrene; Orphenadrine; Phosphodiesterase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Theophylline; Uric Acid; Weight Gain

2008
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:1

    Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System; Diuretics; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Furosemide; Half-Life; Infusions, Intravenous; Injections, Intravenous; Isoniazid; Male; Methylcholanthrene; Orphenadrine; Proadifen; Quinine; Rats; Rats, Sprague-Dawley; Troleandomycin; Weight Gain

2009
Secondary photosensitization of Hydra fusca after exposure to methylcholanthrene.
    Federation proceedings, 1947, Volume: 6, Issue:1 Pt 2

    Topics: Animals; Dermatitis, Phototoxic; Hydra; Light; Methylcholanthrene; Photobiology; Photosensitivity Disorders

1947