Page last updated: 2024-08-18

isomethyleugenol and warfarin

isomethyleugenol has been researched along with warfarin in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199020 (31.75)18.7374
1990's5 (7.94)18.2507
2000's13 (20.63)29.6817
2010's23 (36.51)24.3611
2020's2 (3.17)2.80

Authors

AuthorsStudies
Solomonraj, G; Thomas, BH; Wong, LT1
Anke, H; Zähner, H1
Cooper, JK; Hubbard, JW; McGilveray, IJ; Midha, KK1
Novikov, KN; Sumbalova, Z; Timofeev, KN1
Fujita, T; Hashimoto, K; Sato, T; Satoh, T; Shimada, K; Tadano, K; Yuzuriha, T1
De Vries, JX; Harenberg, J; Simon, M; Zimmermann, R1
Ciavatta, L; Dall'Acqua, F; Marciani, S; Rodighiero, G1
Feuer, G1
Cooper, JK; McGilveray, IJ; Midha, KK1
Agrawal, AK; Brumleve, SJ; Gupta, ML; Parmar, SS1
Chang, CC; Chu, FS; Noh, I1
Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G; Miller, DR1
Adams, RW; Elmore, DT; Jameson, GW; Kyle, WS; Roberts, DV1
Kobayashi, G; Matsuda, Y; Natsuki, R; Tominaga, Y1
Bubeva-Ivanova, L; Erhardt, P; Mahandru, MM; Soine, TO; Zheleva, A1
Deckert, FW2
Deckert, FW; Remmer, HK1
DiAugustine, RP; Eling, TE1
LaFollette, JW; Sanders, RA; Watkins, JB1
Amemiya, M; Ishizuka, M; Kumagai, H; Naganawa, H; Sawa, T; Takeuchi, T1
Jones, BC; Smith, DA; Tyman, CA1
Fang, X; Halpert, JR; Kobayashi, Y1
Hussain, M; Malik, A; Riaz, M; Sadhozai, SK; Ullah, N1
Anzellotti, D; Huner, NP; Ibrahim, RK; NDong, C; Sarhan, F1
Hu, S; Pacholec, M; Tao, J; Walsh, CT1
SHIMAZONO, H1
FINKLE, BJ; MASRI, MS1
Gupta, G; Gupta, RK; Kumar, A; Kumar, P; Kumari, R; Raj, HG; Tyagi, YK; Vohra, P1
Bulfer, S; Collazo, E; Couture, JF; Trievel, RC1
Burkart, MD; Mercer, AC1
Ahn, JH; Hur, HG; Kim, BG; Lee, Y; Lim, Y1
Fukui, M; Hoshikawa, A; Nakazawa, T; Ohsawa, K; Yasuda, T1
Commandeur, JN; De Graaf, C; Keizers, PH; Van Dijk, BR; Van Vugt-Lussenburg, BM; Vermeulen, NP1
Hüttel, W; Müller, M1
Bendig, J; Geissler, D; Hagen, V; Schmidt, R1
Brown, SA1
Dharmaratne, HR; Marasinghe, GP1
Downey, TE; O'Doherty, GA; Rohr, J; Tibrewal, N; Ul Sharif, E; Van Lanen, SG1
Fukushi, Y; Hüner, NP; Ibrahim, RK; Kane, K; Moheb, A; Roy, R; Sarhan, F1
Cattopadhyay, K; Recio, A; Tunge, JA1
Jin, L; Liu, L; Liu, Y; Qin, C; Qiu, Z; Xie, S; Yu, H; Zhou, B; Zhu, F1
Belov, VN; Bierwagen, J; Bottanelli, F; Hell, SW; Nizamov, S; Schill, H1
Bollot, G; Houk, KN; Osuna, S; Parker, MF; Schafmeister, CE; Vaddypally, S; Zdilla, MJ1
Chi, H; Ito, A; Kato, T; Nishino, N; Nsiama, TK; Takemoto, Y; Yoshida, M1
Cigáň, M; Danko, M; Donovalová, J; Gáplovský, A; Gašpar, J; Hrdlovič, P; Stankovičová, H1
Chen, JM; Horn, J; Leggas, M; Rohr, J; Shepherd, MD1
Bracke, ME; Firuzi, O; Khakdan, F; Mathur, D; Miri, R; Nejati, M; Parmar, VS; Parshad, B; Prasad, AK; Saso, L; Sharma, SK1
Cheng, AX; Gao, S; Li, DD; Lou, HX; Xu, RX; Zhang, YY; Zhao, Y1
Duan, C; Huang, P; Li, Y; Zhang, X1
Chen, XY; Huang, XJ; Li, L; Peng, JL; Zhang, CF; Zheng, MY; Zhong, DF1
Qiu, Z; Wang, J; Zheng, G; Zhou, B1
Wang, JQ; Zhang, MZ; Zhang, WH; Zhang, Y1
Burley, GA; Chung, CH; Humphreys, LD; Mosley, JE; Sadler, JC1
Gonzalez, FJ; Li, F; Li, XM; Liu, HN; Zhao, Q1
Gruber-Khadjawi, M; Gutmann, A; Nidetzky, B; Schiller, M1
Fu, W; Ji, B; Wang, Z; Xu, C; Zhu, M1
Bednar, D; Damborsky, J; Dockalova, V; Kokkonen, P; Prokop, Z1
Abadía, J; Álvarez-Fernández, A; Baijot, A; Boutry, M; Cornet, T; Fourmeau, J; Lefèvre, F; Pottier, M1
Huang, C; Kong, L; Sui, Z; Wang, N; Zeng, Z; Zhao, Y1
Romanchikova, N; Trapencieris, P1
Bujalska-Zadrożny, M; Głuch-Lutwin, M; Jeleniewicz, P; Karczyńska, U; Leśniak, A; Mordyl, B; Ostrowska, K; Sacharczuk, M; Siwek, A; Trzaskowski, B1
Bai, P; Liu, T; Zhang, Y; Zhuang, Y1

Other Studies

63 other study(ies) available for isomethyleugenol and warfarin

ArticleYear
Analysis of warfarin in plasma by high-pressure liquid chromatography.
    Journal of chromatography, 1977, May-11, Volume: 135, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Methylation; Warfarin

1977
Metabolic products of microorganisms. 170. On the antibiotic activity of cladosporin.
    Archives of microbiology, 1978, Volume: 116, Issue:3

    Topics: Antifungal Agents; Ascomycota; Bacteria; Chemical Phenomena; Chemistry; Coumarins; Fermentation; Fungi; Isocoumarins; Methylation; Pyrans; Species Specificity; Spores, Fungal

1978
GLC determination of plasma concentrations of phenprocoumon.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:3

    Topics: Alkylating Agents; Aniline Compounds; Animals; Chromatography, Gas; Coumarins; Dogs; Drug Stability; Humans; In Vitro Techniques; Methods; Methylation; Phenprocoumon; Phenytoin; Time Factors

1976
[The effect of lysolecithin on rat liver microsome monooxygenase activity after induction by xenobiotics of the methylcholanthrene type].
    Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:12

    Topics: Animals; Anisoles; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Coumarins; Enzyme Induction; Hydroxylation; Intracellular Membranes; Lysophosphatidylcholines; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Polychlorinated Biphenyls; Rats; Substrate Specificity

1992
Identification of menaquinone-4 metabolites in the rat.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:10

    Topics: Animals; Bile; Chemical Phenomena; Chemistry, Physical; Gas Chromatography-Mass Spectrometry; Hydrolysis; Liver; Male; Methylation; Rats; Rats, Inbred Strains; Scintillation Counting; Vitamin K; Vitamin K 2; Warfarin

1989
Identification of phenprocoumon metabolites in human urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
    Journal of chromatography, 1985, Mar-22, Volume: 338, Issue:2

    Topics: 4-Hydroxycoumarins; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Methylation; Phenprocoumon; Warfarin

1985
Formation of inter-strand cross-linkings in the photoreactions between furocoumarins and DNA.
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1971, Volume: 26, Issue:6

    Topics: Animals; Binding Sites; Carbon Isotopes; Cattle; Coumarins; DNA; Fluorometry; Methylation; Photochemistry; Pyrimidines; Spectrophotometry

1971
3-Hydroxylation of coumarin or 4-methylcoumarin by rat-liver microsomes and its induction by 4-methylcoumarin given orally.
    Chemico-biological interactions, 1970, Volume: 2, Issue:3

    Topics: Animals; Coumarins; Dactinomycin; Enzyme Induction; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; NAD; NADP; Phospholipases; Proadifen; Proteins; Rats; Surface-Active Agents

1970
GLC determination of plasma levels of warfarin.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:11

    Topics: Chromatography, Gas; Diazonium Compounds; Humans; Indicators and Reagents; Male; Mass Spectrometry; Methods; Methylation; Phenylbutazone; Spectrophotometry, Ultraviolet; Warfarin

1974
Antiestrogenic activity of substituted coumarins.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:3

    Topics: Animals; Coumarins; Diethylstilbestrol; Estrogen Antagonists; Female; Lethal Dose 50; Methylation; Muscle Contraction; Organ Size; Rats; Uterus

1974
Structural requirements for ochratoxin intoxication.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, May-15, Volume: 11, Issue:10

    Topics: Animals; Chickens; Chromatography, Gel; Coumarins; Hydroxylation; Lethal Dose 50; Methylation; Mycotoxins; Ochratoxins; Phenols; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1972
The influence of methyl groups on toxicity and drug metabolism.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:1

    Topics: Administration, Oral; Amphetamine; Animals; Carbon Isotopes; Coumarins; Enzyme Induction; Female; Humans; Mephobarbital; Methylation; Microscopy, Electron; Microsomes, Liver; Nicotine; Phenobarbital; Phenols; Phospholipids; Pyrazoles; Rats; Structure-Activity Relationship; Tritium

1973
Determination of the operational molarity of solutions of bovine alpha-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration.
    The Biochemical journal, 1973, Volume: 131, Issue:1

    Topics: Animals; Benzoates; Cattle; Chymotrypsin; Cinnamates; Coumarins; Esters; Factor X; Guanidines; Methylation; Naphthols; Quaternary Ammonium Compounds; Spectrometry, Fluorescence; Subtilisins; Thrombin; Time Factors; Trypsin

1973
[Studies on coumarin derivatives. I. Synthesis of 3-cyano-7-hydroxy-4-methylthiocoumarin].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1973, Volume: 93, Issue:7

    Topics: Coumarins; Cyanates; Methylation

1973
Natural coumarins. VII. Isolation and structure of a new coumarin, peuruthenicin, from Peucedanum ruthenicum M.B.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:11

    Topics: Carboxylic Acids; Coumarins; Decarboxylation; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methods; Methylation; Plants; Spectrophotometry, Ultraviolet; Umbelliferones

1973
Gas-liquid chromatography of coumarin anticoagulants and their trimethylsilyl ethers.
    Journal of chromatography, 1972, Feb-02, Volume: 64, Issue:2

    Topics: Anticoagulants; Chromatography, Gas; Coumarins; Ethers; Hydroxylation; Methylation; Plant Extracts; Silicon

1972
Gas-liquid chromatography of coumarin anticoagulants, their trimethylsilyl ethers, acetates, trichloroacetates, and trifluoroacetates.
    Journal of chromatography, 1972, Jun-28, Volume: 69, Issue:1

    Topics: Acetates; Anticoagulants; Benzyl Compounds; Chlorides; Chromatography, Gas; Coumarins; Esters; Ethers; Fluoroacetates; Hydroxylation; Methylation; Silicon; Temperature; Warfarin

1972
In vitro inhibition of rat and human liver microsomal enzymes by 4-hydroxycoumarin anticoagulants and related compounds.
    Chemico-biological interactions, 1972, Volume: 5, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Anticoagulants; Binding Sites; Coumarins; Humans; Kinetics; Methylation; Microsomes, Liver; Oxidoreductases; Rats; Salicylates; Species Specificity; Spectrum Analysis; Warfarin

1972
A role for phospholipids in the binding and metabolism of drugs by hepatic microsomes. Use of the fluorescent hydrophobic probe 1-anilinonaphthalene-8-sulphonate.
    The Biochemical journal, 1971, Volume: 123, Issue:4

    Topics: Aniline Compounds; Animals; Benzphetamine; Ethylamines; Fluorescence; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Naphthalenes; Pharmaceutical Preparations; Phosphatidylcholines; Phospholipases; Phospholipids; Proadifen; Rats; Receptors, Drug; Spectrophotometry; Sulfonic Acids; Trypsin; Warfarin

1971
Biotransformation in Egyptian spiny mouse Acomys cahirinus.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 110, Issue:1

    Topics: 2-Naphthylamine; Animals; Benzo(a)pyrene; Benzphetamine; Biotransformation; Coumarins; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Epoxide Hydrolases; Epoxy Compounds; Ethacrynic Acid; Female; Fluorenes; Glucuronosyltransferase; Glutathione Transferase; Intestines; Kidney; Liver; Male; Methylation; Muridae; Naphthols; Oxazines; Oxygenases; Sex Factors

1995
Biosynthesis of antitumor antibiotic, cytogenin.
    The Journal of antibiotics, 1994, Volume: 47, Issue:4

    Topics: Acetates; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Coumarins; Culture Media; Hydroxylation; Isocoumarins; Magnetic Resonance Spectroscopy; Methionine; Methylation; Prodrugs; Spectrophotometry, Ultraviolet; Streptomycetaceae

1994
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:10

    Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline

1997
Stoichiometry of 7-ethoxycoumarin metabolism by cytochrome P450 2B1 wild-type and five active-site mutants.
    FEBS letters, 1997, Oct-13, Volume: 416, Issue:1

    Topics: Binding Sites; Coumarins; Cytochrome P-450 CYP2B1; Hydrogen Peroxide; Methylation; Mutation; NADP; Recombinant Proteins; Water

1997
Daphwazirin, biscoumarin glycopyranoside from Daphne oleoides.
    Natural product letters, 2001, Volume: 15, Issue:6

    Topics: Chromatography; Coumarins; Glycosides; Hydrolysis; Medicine, Traditional; Methylation; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pakistan; Plant Roots; Plants, Medicinal; Stereoisomerism; Thymelaeaceae

2001
Daphnetin methylation by a novel O-methyltransferase is associated with cold acclimation and photosystem II excitation pressure in rye.
    The Journal of biological chemistry, 2003, Feb-28, Volume: 278, Issue:9

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Caffeic Acids; Cell Division; Chromatography, Thin Layer; Cold Temperature; Coumaric Acids; Coumarins; DNA, Complementary; Gene Library; Lignin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Methyltransferases; Molecular Sequence Data; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Phylogeny; Protons; Recombinant Proteins; Secale; Sequence Homology, Amino Acid; Spectrophotometry; Temperature; Ultraviolet Rays; Umbelliferones

2003
Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway.
    Organic letters, 2003, Sep-04, Volume: 5, Issue:18

    Topics: Anti-Bacterial Agents; Catalysis; Coumarins; Cyclization; Endopeptidases; Esterases; Keto Acids; Kinetics; Lipase; Methylation; Molecular Structure; Oxidation-Reduction; Stereoisomerism

2003
Investigations on lignins and lignification. XXI. Identification of phenolic esters in the culture medium of Lentinus lepideus and the O-methylation of methyl P-coumarate to methyl P-methoxycinnamate in vivo.
    Archives of biochemistry and biophysics, 1959, Volume: 83, Issue:1

    Topics: Cinnamates; Coumarins; Esters; Fungi; Lentinula; Lignin; Methylation

1959
METHYLATION OF POLYHYDROXYAROMATIC COMPOUNDS BY PAMPAS GRASS O-METHYLTRANSFERASE.
    Biochimica et biophysica acta, 1964, Apr-06, Volume: 85

    Topics: Benzoates; Carbon Isotopes; Chromatography; Cinnamates; Coumarins; Flavonoids; Gallic Acid; Metabolism; Methylation; Methyltransferases; Poaceae; Pyrogallol; Research; Transferases

1964
Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity.
    European journal of medicinal chemistry, 2005, Volume: 40, Issue:4

    Topics: Acetylation; Amination; Animals; Antioxidants; Coumarins; Inhibitory Concentration 50; Lipid Peroxidation; Liver; Male; Methylation; Molecular Structure; NADP; Rats; Rats, Wistar; Structure-Activity Relationship

2005
A coupled fluorescent assay for histone methyltransferases.
    Analytical biochemistry, 2005, Jul-01, Volume: 342, Issue:1

    Topics: Adenosylhomocysteinase; Coumarins; Fluorescent Dyes; Fluorometry; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homocysteine; Kinetics; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Schizosaccharomyces; Sulfolobus solfataricus

2005
Chemical expansion of cofactor activity.
    Nature chemical biology, 2006, Volume: 2, Issue:1

    Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates

2006
Production of three O-methhylated esculetins with Escherichia coli expressing O-methyltransferase from poplar.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:5

    Topics: Biotransformation; Chromatography, High Pressure Liquid; Coumarins; Escherichia coli; Industrial Microbiology; Methylation; Plant Proteins; Populus; Protein O-Methyltransferase; Scopoletin; Umbelliferones

2006
Metabolic fate of fraxin administered orally to rats.
    Journal of natural products, 2006, Volume: 69, Issue:5

    Topics: Animals; Coumarins; Feces; Intestines; Liver; Male; Methylation; Molecular Structure; Rats; Rats, Sprague-Dawley

2006
Metabolism of N-substituted 7-methoxy-4-(aminomethyl) -coumarins by cytochrome P450 2D6 mutants and the indication of additional substrate interaction points.
    Xenobiotica; the fate of foreign compounds in biological systems, 2006, Volume: 36, Issue:9

    Topics: Alkylation; Binding Sites; Catalysis; Coumarins; Cytochrome P-450 CYP2D6; Humans; Hydrophobic and Hydrophilic Interactions; Methylation; Models, Molecular; Mutant Proteins; Mutation; Substrate Specificity

2006
Regio- and stereoselective intermolecular oxidative phenol coupling in kotanin biosynthesis by Aspergillus niger.
    Chembiochem : a European journal of chemical biology, 2007, Mar-26, Volume: 8, Issue:5

    Topics: Aspergillus niger; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Circular Dichroism; Coumarins; Magnetic Resonance Spectroscopy; Methylation; Models, Chemical; Oxygen; Phenol; Stereoisomerism; Umbelliferones

2007
Mechanism of photocleavage of (coumarin-4-yl)methyl esters.
    The journal of physical chemistry. A, 2007, Jul-05, Volume: 111, Issue:26

    Topics: Acids; Alcohols; Coumarins; Cyclic AMP; Esters; Methylation; Molecular Structure; Photolysis

2007
Dr. Stewart A. Brown (PSNA phytochemistry pioneer).
    Phytochemistry, 2007, Volume: 68, Issue:14

    Topics: Awards and Prizes; Biochemistry; Canada; Coumarins; History, 20th Century; Lignin; Methylation; Nicotine; Plants; Societies, Scientific

2007
New methylethers of cordatolides from Calophyllum cordato-oblongum and their synthesis.
    Natural product research, 2009, Volume: 23, Issue:10

    Topics: Anti-HIV Agents; Calophyllum; Coumarins; Magnetic Resonance Spectroscopy; Methyl Ethers; Methylation; Molecular Structure; Plant Extracts; Sitosterols; Triterpenes

2009
Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.
    Journal of the American Chemical Society, 2012, Aug-01, Volume: 134, Issue:30

    Topics: Antibiotics, Antineoplastic; Coumarins; Glycosides; Methylation; Methyltransferases; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine; Streptomyces

2012
Daphnetin methylation stabilizes the activity of phosphoribulokinase in wheat during cold acclimation.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2012, Volume: 90, Issue:5

    Topics: Acclimatization; Cold Temperature; Coumarins; Mass Spectrometry; Methylation; Phosphotransferases (Alcohol Group Acceptor); Ribulosephosphates; RNA, Messenger; Triticum; Umbelliferones

2012
Palladium-catalyzed, pyrrolidine-mediated arylmethylation of ketones and aldehydes with coumarinyl(methyl) acetates.
    Organic & biomolecular chemistry, 2012, Sep-14, Volume: 10, Issue:34

    Topics: Acetates; Aldehydes; Catalysis; Coumarins; Ketones; Methylation; Palladium; Pyrrolidines

2012
In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Colon; Coumarins; Ellagic Acid; Enterobacteriaceae; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lipid Peroxidation; MAP Kinase Signaling System; Methylation; Neoplasm Proteins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Reactive Oxygen Species; Urinary Bladder Neoplasms

2013
4-Trifluoromethyl-substituted coumarins with large Stokes shifts: synthesis, bioconjugates, and their use in super-resolution fluorescence microscopy.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Dec-02, Volume: 19, Issue:49

    Topics: Coumarins; Fluorescent Dyes; Halogenation; HeLa Cells; Humans; Methylation; Microscopy, Fluorescence

2013
Acceleration of an aromatic Claisen rearrangement via a designed spiroligozyme catalyst that mimics the ketosteroid isomerase catalytic dyad.
    Journal of the American Chemical Society, 2014, Mar-12, Volume: 136, Issue:10

    Topics: Biomimetic Materials; Catalysis; Coumarins; Hydrogen Bonding; Methylation; Models, Molecular; Steroid Isomerases

2014
Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors.
    Bioorganic & medicinal chemistry, 2014, Feb-15, Volume: 22, Issue:4

    Topics: Amino Acid Sequence; Coumarins; Drug Design; Enzyme Activation; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Methylation; Peptides; Substrate Specificity; Transcription, Genetic

2014
3-(7-Dimethylamino)coumarin N-phenylsemicarbazones in solution and polymer matrices: Tuning their fluorescence via para-phenyl substitution.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, May-21, Volume: 126

    Topics: Amination; Coumarins; Fluorescence; Fluorescent Dyes; Hydrogen Bonding; Methylation; Polymers; Semicarbazones; Solvents; Spectrometry, Fluorescence

2014
Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent.
    Chembiochem : a European journal of chemical biology, 2014, Dec-15, Volume: 15, Issue:18

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coumarins; Glycosides; Humans; Methylation; Neoplasms; Streptomyces; Structure-Activity Relationship

2014
Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents.
    Pharmaceutical biology, 2016, Volume: 54, Issue:1

    Topics: Antineoplastic Agents; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; K562 Cells; MCF-7 Cells; Methylation; Molecular Structure; Neoplasms; Structure-Activity Relationship

2016
Functional characterization of a plastidal cation-dependent O-methyltransferase from the liverwort Plagiochasma appendiculatum.
    Phytochemistry, 2015, Volume: 118

    Topics: Anthocyanins; Cations; Coumarins; DNA, Complementary; Flavonoids; Hepatophyta; Methylation; Methyltransferases; Phenylpropionates; Phylogeny

2015
A mild and fast continuous-flow trifluoromethylation of coumarins with the CF3 radical derived from CF3SO2Na and TBHP.
    Organic & biomolecular chemistry, 2015, Nov-28, Volume: 13, Issue:44

    Topics: Catalysis; Chemistry Techniques, Synthetic; Copper; Coumarins; Equipment Design; Halogenation; Indicators and Reagents; Methylation; tert-Butylhydroperoxide

2015
Wedelolactone metabolism in rats through regioselective glucuronidation catalyzed by uridine diphosphate-glucuronosyltransferases 1As (UGT1As).
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Apr-15, Volume: 23, Issue:4

    Topics: Animals; Asteraceae; Biological Availability; Coumarins; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Intestinal Mucosa; Kidney; Liver; Male; Mass Spectrometry; Methylation; Microsomes; Molecular Docking Simulation; Plant Extracts; Protein Isoforms; Rats; UDP-Glucuronosyltransferase 1A9; Uridine Diphosphate

2016
Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 97

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Blotting, Western; Cell Proliferation; Coumarins; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 1-alpha; Humans; Lymphoid Enhancer-Binding Factor 1; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2016
Design, Synthesis and Antifungal Activity of Coumarin Ring-Opening Derivatives.
    Molecules (Basel, Switzerland), 2016, Oct-17, Volume: 21, Issue:10

    Topics: Antifungal Agents; Botrytis; Coumarins; Hydrolysis; Methylation; Molecular Structure; Structure-Activity Relationship

2016
Structural and Functional Basis of C-Methylation of Coumarin Scaffolds by NovO.
    ACS chemical biology, 2017, 02-17, Volume: 12, Issue:2

    Topics: Catalysis; Coumarins; Crystallography, X-Ray; Methylation; Methyltransferases; Molecular Structure; Novobiocin; Streptomyces; Substrate Specificity

2017
Metabolic map of osthole and its effect on lipids.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:3

    Topics: Administration, Oral; Animals; Chromatography, Liquid; Coumarins; Hydrogenation; Hydroxylation; Inactivation, Metabolic; Lipids; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolomics; Methylation; Mice; Microsomes, Liver; Molecular Structure; Peritoneal Absorption; Spectrometry, Mass, Electrospray Ionization

2018
An ortho C-methylation/O-glycosylation motif on a hydroxy-coumarin scaffold, selectively installed by biocatalysis.
    Organic & biomolecular chemistry, 2017, Sep-26, Volume: 15, Issue:37

    Topics: Biocatalysis; Coumarins; Glycosylation; Glycosyltransferases; Hydroxides; Malus; Methylation; Methyltransferases; Molecular Structure; Streptomyces

2017
Visible-light-mediated direct difluoromethylation of alkynoates: synthesis of 3-difluoromethylated coumarins.
    Organic & biomolecular chemistry, 2017, Nov-07, Volume: 15, Issue:43

    Topics: Alkynes; Chemistry Techniques, Synthetic; Coumarins; Cyclization; Fluorine; Light; Methylation; Models, Molecular; Photochemical Processes

2017
Conformational changes allow processing of bulky substrates by a haloalkane dehalogenase with a small and buried active site.
    The Journal of biological chemistry, 2018, 07-20, Volume: 293, Issue:29

    Topics: Catalytic Domain; Coumarins; Crystallography, X-Ray; Ethylene Dichlorides; Halogenation; Hydrolases; Kinetics; Methylation; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Conformation; Substrate Specificity; Xanthobacter

2018
The Nicotiana tabacum ABC transporter NtPDR3 secretes O-methylated coumarins in response to iron deficiency.
    Journal of experimental botany, 2018, 08-14, Volume: 69, Issue:18

    Topics: ATP-Binding Cassette Transporters; Coumarins; Gene Expression Regulation, Plant; Iron Deficiencies; Methylation; Nicotiana; Oxygen; Plant Cells; Plant Proteins; Plant Roots; Rhizosphere

2018
The Molecular and Structural Basis of
    International journal of molecular sciences, 2019, Mar-27, Volume: 20, Issue:7

    Topics: Amino Acid Sequence; Apiaceae; Biosynthetic Pathways; Coumarins; Data Mining; Evolution, Molecular; Furocoumarins; Gene Duplication; Heterozygote; Methylation; Methyltransferases; Molecular Docking Simulation; Phytochemicals; S-Adenosylhomocysteine; Sequence Analysis, RNA; Substrate Specificity; Transcriptome; Umbelliferones

2019
Wedelolactone Targets EZH2-mediated Histone H3K27 Methylation in Mantle Cell Lymphoma.
    Anticancer research, 2019, Volume: 39, Issue:8

    Topics: Cell Line, Tumor; Cell Proliferation; Coumarins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histone Code; Histone Methyltransferases; Histones; Humans; Lymphoma, Mantle-Cell; Methylation; Polycomb Repressive Complex 2

2019
6-Acetyl-5-hydroxy-4,7-dimethylcoumarin derivatives: Design, synthesis, modeling studies, 5-HT
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Acetylation; Animals; CHO Cells; Coumarins; Cricetulus; Drug Design; Drug Discovery; Humans; Male; Methylation; Mice, Inbred BALB C; Molecular Docking Simulation; Piperazine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Antagonists

2020
Two
    Journal of natural products, 2022, 08-26, Volume: 85, Issue:8

    Topics: Cnidium; Coumarins; Methylation; Methyltransferases; Plants, Medicinal

2022