isomethyleugenol has been researched along with vitamin b 12 in 292 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (37.67) | 18.7374 |
| 1990's | 59 (20.21) | 18.2507 |
| 2000's | 50 (17.12) | 29.6817 |
| 2010's | 57 (19.52) | 24.3611 |
| 2020's | 16 (5.48) | 2.80 |
| Authors | Studies |
|---|---|
| Curtius, HC; Zagalak, B | 1 |
| Arigoni, D | 1 |
| Cheh, A; Dizikes, LJ; Lakowicz, JR; Rakow, S; Ridley, WP; Wood, JM | 1 |
| Grate, JH; Katz, RN; Schrauzer, GN | 1 |
| Bukin, IuV; Krasnova, TP; Orlova, NV | 1 |
| Battersby, AR; Golding, BT; Ihara, M; McDonald, E; Redfern, JR | 1 |
| Battersby, AR; Hollenstein, R; Ihara, M; McDonald, E; Satoh, F; Williams, DC | 1 |
| Imura, N; Pan, SK; Shimizu, M; Tonomura, K; Ukita, T | 1 |
| Fanchiang, YT; Ridley, WP; Wood, JM | 1 |
| Fendler, JH; Nome, F; Robinson, GC | 1 |
| Dizikes, LJ; Ridley, WP; Wood, JM | 1 |
| Hanna, ML; Taylor, RT | 4 |
| Andersson, S; Nylander, B | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH | 1 |
| Hamdy, MK; Noyes, OR | 1 |
| Metz, J | 1 |
| Hidaka, T; Imai, S; Kamigiri, K; Kuzuyama, T; Seto, H | 1 |
| Munder, M; Renz, P; Vogler, B; Vogt, JR | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Drummond, JT; Ludwig, ML; Luschinsky, CL; Matthews, RG | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Blanche, F; Cameron, B; Crouzet, J; Debussche, L; Famechon, A; Thibaut, D | 1 |
| Dirheimer, G; Keith, G; Pfohl-Leszkowicz, A | 1 |
| Cao, XJ; Krzycki, JA | 1 |
| Binková, B; Fojtíková, I; Srám, RJ; Topinka, J | 1 |
| Blanche, F; Debussche, L; Thibaut, D | 1 |
| Battersby, AR; Blanche, F; Debussche, L; Leeper, FJ; Thibaut, D | 1 |
| Smith, JT; Zorn, NE | 1 |
| Roessner, CA; Santander, PJ; Scott, AI; Sowa, BA; Stolowich, NJ; Warren, MJ | 1 |
| Chanarin, I; Deacon, R; Green, R; Lumb, M; Perry, J; Purkiss, P | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Feinberg, BA; Harder, SR; Lu, WP; Ragsdale, SW | 1 |
| Banerjee, RV; Dunham, WR; Frasca, V; Matthews, RG; Sands, RH | 1 |
| Bratt, GT; Hogenkamp, HP; Sun, SZ | 1 |
| Bykhovskiĭ, VIa; Dmitrovskiĭ, AA; Liudkovskaia, IV; Podlepa, EM | 1 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Renz, P; Vogt, JR | 1 |
| Scott, AI | 1 |
| Leeper, FJ | 1 |
| Shane, B; Stokstad, EL | 1 |
| Buchet, JP; Lauwerys, R | 1 |
| Taylor, CD; Wolfe, RS | 1 |
| Valencia, R | 1 |
| Babior, BM; Brown, DG; Law, PY; Lien, EL; Wood, JM | 1 |
| Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
| Friedrich, W; Nordmeyer, JP | 2 |
| Friedrich, W; Messerschmidt, R | 1 |
| Friedrich, W; Moskophidis, M | 1 |
| Kühnle, HF; Renz, P | 1 |
| Friedrich, W; Moskophidis, M; Pohl, CM | 1 |
| Mulherkar, L; Telang, NT | 1 |
| Smith, DA; Whitehouse, JM | 1 |
| Obata, N | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Bukin, VN; Pantskhava, ES | 1 |
| Königk, E; Ossikovski, E; Schmidt, G | 1 |
| Bouveng, R | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Thayer, JS | 1 |
| Charbonneau, L; DeSimone, RE; Hill, HA; Penley, MW; Pratt, JM; Ridsdale, S; Smith, SG; Williams, RJ; Wood, JM | 1 |
| Ghambeer, RK; Ljungdahl, LG; Schulman, M; Wood, HG | 1 |
| Cushley, RJ; Scott, AI; Townsend, CA | 1 |
| Sharma, DC | 1 |
| Kass, L | 1 |
| Taylor, RT; Weissbach, H | 4 |
| Jaenicke, L; Stavrianopoulos, J | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Taylor, RT | 3 |
| Bertilsson, L; Neujahr, HY | 1 |
| Rüdiger, H | 1 |
| Fenrych, W; Huang, HH; Johnson, BC; Pawelkiewicz, J | 1 |
| Calhoun, DH; Feary, TW | 1 |
| Alworth, WL; Lu, SH | 1 |
| Fukui, S; Isemura, Y; Kondo, M; Toraya, T | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH; Shih, VE; Uhlendorf, BW | 1 |
| Kajiwara, M; Okada, K; Scott, AI; Townsend, CA; Whitman, PJ | 1 |
| Penley, MW; Wood, JM | 1 |
| Barness, LA; Morrow, G | 1 |
| Woodward, RB | 1 |
| Bradbeer, C | 1 |
| Agnes, G; Hill, HA; Kennedy, FS; Pratt, JM; Ridsdale, SC; Williams, RJ | 1 |
| Ghambeer, RK; Ljungdahl, L; Schulman, M; Wood, HG | 1 |
| Curri, SB | 1 |
| Fukui, S; Shimizu, S; Sugimoto, Y; Tamao, Y; Toraya, T | 1 |
| Mahoney, MJ; Mudd, SH; Rosenberg, LE; Uhlendorf, BW | 1 |
| Járai, M | 1 |
| Sangiuolo, F | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 1 |
| Fujii, K; Fukui, S | 1 |
| Imura, N; Kim, JY; Kwan, T; Nagao, K; Pan, SK; Sukegawa, E; Ukita, T | 1 |
| Demain, AL; White, RF | 1 |
| Sovik, O | 1 |
| Blaylock, BA | 1 |
| Kennedy, FS; Rosen, CG; Wood, JM | 1 |
| Easley, LW | 1 |
| Burton, EG; Sakami, W | 1 |
| Agatov, PA; Galanina, LA | 1 |
| Carney, MW; Reynolds, EH; Toone, BK | 1 |
| van der Drift, C; van der Lest, C; van der Meijden, P; Vogels, GD | 1 |
| Imura, N; Pan-Hou, HS | 1 |
| Bratt, GT; Fanchiang, YT; Hogenkamp, HP | 1 |
| Bartha, R; Compeau, G | 1 |
| Kliasheva, RI | 2 |
| Deacon, R; Lumb, MJ; Perry, J | 1 |
| Chanarin, I | 1 |
| Deguchi, T; Marumo, H; Okumura, S | 1 |
| Hosono, M; Imura, N; Pan-Hou, HS | 1 |
| Harii, K; Iwamori, M; Kitano, Y; Nakahara, M; Takaoka, T | 1 |
| Gottfries, CG; Johansson, BV; Regland, B | 1 |
| Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Scott, JM; Weir, DG | 1 |
| Gärtner, P; Thauer, RK; Weiss, DS | 1 |
| Kreft, JU; Schink, B | 1 |
| Stubbe, J | 1 |
| Drennan, CL; Drummond, JT; Huang, S; Ludwig, ML; Matthews, RG | 1 |
| Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM | 1 |
| Drummond, JT; Matthews, RG | 1 |
| Battersby, AR | 1 |
| Rees, MM; Rodgers, GM | 1 |
| Chen, C; Hedstrom, O; Whanger, PD | 1 |
| Barkhof, F; Braam, M; Frequin, ST; Hommes, OR; Wevers, RA | 1 |
| Cao, X; Kremer, JD; Krzycki, J | 1 |
| Min, C; Ozaki, SI; Roessner, CA; Scott, AI; Spencer, JB; Stolowich, NJ | 1 |
| Surtees, R | 1 |
| Bartha, R; Choi, SC | 1 |
| May, BA | 1 |
| Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E | 1 |
| Church, GM; Kieffer-Higgins, S; Lawrence, JG; Roth, JR; Rubenfield, M | 1 |
| Belozerova, EV; Iurkevich, AM; Kliasheva, RI; Nikol'skaia, II; Sharkova, EV | 1 |
| Allen, RH; Buring, JE; Gaziano, JM; Hennekens, CH; Kok, FJ; Reynolds, RD; Stabler, SP; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Delnomdedieu, M; Styblo, M; Thomas, DJ | 1 |
| Dixon, MM; Huang, S; Ludwig, M; Matthews, RG | 1 |
| Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH | 1 |
| Bottiglieri, T | 1 |
| Goulding, CW; Matthews, RG; Postigo, D | 1 |
| Boiocchi, M; Corona, G; Donada, C; Fabris, M; Toffoli, G; Viel, A; Zarrelli, A | 1 |
| Fiskerstrand, T; Refsum, H; Ueland, PM | 1 |
| Holderman, MT; Roessner, CA; Santander, PJ; Scott, AI; Stolowich, NJ | 1 |
| George, SE; Hall, LL; Kohan, MJ; Styblo, M; Thomas, DJ | 1 |
| Goulding, CW; Matthews, RG | 2 |
| Huang, S; Jarrett, JT; Matthews, RG | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Boddie, AM; Dembure, PP; Elsas, LJ; Fisher, AJ; Macmahon, W; Saxe, D; Steen, MT; Sullivan, KM | 1 |
| Hoover, DM; Jarrett, JT; Ludwig, ML; Matthews, RG | 1 |
| Ekblom, J; Löfberg, C; Oreland, L; Yassin, MS | 1 |
| Aposhian, HV; Zakharyan, RA | 1 |
| Cattaneo, M | 1 |
| Albanes, D; Hartman, TJ; Nieto, FJ; Rautalahti, M; Sehlub, J; Stolzenberg-Solomon, RZ; Tangrea, JA; Taylor, PR; Virtamo, J | 1 |
| Menon, S; Ragsdale, SW | 1 |
| Dudman, NP; Elsworth, GR; Guo, XW; Kelly, FD; Li, D; Mann, NJ; Sinclair, AJ; Wilson, AK | 1 |
| Scott, JM; Weir, DG | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| Briddon, A; Patel, N | 1 |
| Krzycki, JA; Paul, L; Tallant, TC | 1 |
| Bandarian, V; Matthews, RG | 1 |
| Naidu, D; Ragsdale, SW | 1 |
| Di Rocco, A; Simpson, DM | 1 |
| Maeda, Y; Momoshima, N; Osaki, S; Song, LX | 1 |
| Daskalakis, I; Hinkins, M; Lucock, M; Yates, Z | 1 |
| Cimmino, A; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Romano, M; Satta, E; Zappia, V | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K | 1 |
| Brand, U; Rombach, M; Seebacher, J; Vahrenkamp, H | 1 |
| Bottiglieri, T; Di Rocco, A; Geraci, A; Godbold, J; Morgello, S; Simpson, D; Werner, P | 1 |
| Díaz, M; Freixas, E; Schiel, A; Trimarchi, H | 1 |
| Hoffer, LJ | 1 |
| Allawi, J; Horrobin, DF; Loder, C | 1 |
| Ellern, A; Espenson, JH; Shan, X | 1 |
| Zhu, BT | 1 |
| Beilin, LJ; Burke, V; Croft, KD; Hodgson, JM; Puddey, IB | 1 |
| Banerjee, R; Oltean, S | 1 |
| Gastaldo, L; Marinelli, F | 1 |
| Bandarian, V; Ludwig, ML; Matthews, RG | 1 |
| KRATZER, FH | 1 |
| FATTERPAKER, P; MARFATIA, U; SREENIVASAN, A | 1 |
| OERIU, S; TANASE, I | 2 |
| Chow, BF; Ranke, B; Ranke, E | 1 |
| Bailey, LB | 1 |
| GILLIS, MB; NORRIS, LC | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Galezowski, W | 1 |
| Roessner, CA; Scott, AI; Williams, HJ | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| Celo, V; Lean, DR; Scott, SL | 1 |
| Pichon-Santander, C; Santander, PJ; Scott, AI | 1 |
| Loscalzo, J | 1 |
| Toohey, JI | 1 |
| Botha, J; Erasmus, RT; Haug, P; Hendricks, M; Hon, D; Kotze, MJ; Kuyler, J; Matsha, T; Potocnik, FC; van Rensburg, SJ | 1 |
| Roessner, CA; Scott, AI | 1 |
| Eichmüller, C; Fasching, M; Gschösser, S; Kräutler, B; Perschinka, H | 1 |
| Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R | 1 |
| Burke, V; Hodgson, JM; Puddey, IB; van Bockxmeer, FM | 1 |
| Bendini, MG; Cozzari, L; De Cristofaro, R; Farina, SM; Giordano, A; Giordano, G; Lanza, GA; Leggio, M; Mazza, A; Menichini, G; Moriconi, E | 1 |
| Ahsan, H; Baron, JA; Chen, Y; Gamble, MV; Graziano, JH; Heck, JE; Howe, GR; Parvez, F; Slavkovich, V | 1 |
| Dosch, HM; Fish, EN; Galligan, C; Mastronardi, FG; Moscarello, MA; Selvanantham, T; Tsui, H; Winer, S; Wood, DD | 1 |
| Brunold, TC; Fleischhacker, AS; Liptak, MD; Matthews, RG | 1 |
| Brindley, AA; Brocklehurst, K; Deery, E; Frank, S; Heathcote, P; Lawrence, A; Leech, HK; Pickersgill, RW; Rigby, SE; Schubert, HL; Warren, MJ | 1 |
| Dougherty, WG; Eckert, NA; Riordan, CG; Yap, GP | 1 |
| Huang, S; Lesley, SA; Ludwig, M; Matthews, RG; Pattridge, K; Romanchuk, G; Wilson, IA | 1 |
| Iida, K; Kajiwara, M | 1 |
| Fanghänel, J; Gedrange, T; Maile, S; Proff, P; Weingärtner, J | 1 |
| Bomer, TM; Koutmos, M; Ludwig, ML; Matthews, RG; Pejchal, R; Smith, JL | 1 |
| Ekstrom, EB; Morel, FM | 1 |
| Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Llanos, M; Montequin, MJ; Pinardi, G; Ronco, AM | 1 |
| Fuchs, G; Gaylor, DW; Hubanks, A; James, SJ; Jernigan, S; Melnyk, S; Pavliv, O; Reid, T | 1 |
| de Jonge, R; de Vries, JH; Eijkemans, MJ; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Meurs, JB | 1 |
| Hisaeda, Y; Masuko, T; Pan, L; Shimakoshi, H | 1 |
| Brustolin, S; Félix, TM; Giugliani, R | 1 |
| Kuroda, Y; Moritomo, H; Murase, T; Okada, K; Okamoto, M; Tanaka, H; Temporin, K; Yoshikawa, H | 1 |
| Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S | 1 |
| Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN | 1 |
| de Jonge, R; Helbing, WA; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; Wildhagen, MF | 1 |
| El-Saden, S; Hathout, L | 1 |
| Babeluk, R; Gerner, C; Jakobsen, LH; Kondrup, J; Roth, E; Umlauf, E; Volf, I; Zellner, M | 1 |
| Alvarez, RD; Badiga, S; Chen, M; Edberg, JC; Johanning, GL; Macaluso, M; Partridge, EE; Piyathilake, CJ; Siddiqui, NR | 1 |
| Böhlke, M; Broersen, LM; Hageman, RJ; Kamphuis, PJ; Maher, TJ; van Wijk, N; Watkins, CJ; Wurtman, RJ | 1 |
| Diaz-Bone, RA; Hensel, R; Huber, B; Schmitz, RA; Thomas, F; Weidenbach, K; Wuerfel, O | 1 |
| Liu, W; van der Donk, WA; Zhang, Q | 1 |
| Ando, N; Bender, G; Blasiak, LC; Doukov, TI; Drennan, CL; Kung, Y; Ragsdale, SW; Seravalli, J | 1 |
| Alberto, JM; Blaise, S; Bressenot, A; Bronowicki, JP; Daval, JL; Giudicelli, J; Guéant, JL; Guéant-Rodriguez, RM; Gueguen, N; Jeannesson, E; Malthiery, Y; Moreno Garcia, M; Nicolas, B; Peyrin-Biroulet, L; Pooya, S | 1 |
| Morris, MS | 1 |
| Banasiuk, R; Banecka-Majkutewicz, Z; Banecki, B; Grabowski, M; Kędzierska, B; Lica, J; Węgrzyn, A | 1 |
| Greule, M; Jochmann, MA; Keppler, F; Schmidt, TC; Wuerfel, O | 1 |
| Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L | 1 |
| Anand, P; Devi, S; Dwarkanath, P; Hsu, JW; Jahoor, F; Kurpad, AV; Mhaskar, R; Thomas, A; Thomas, T | 1 |
| Chan, KK; O'Hagan, D; Thompson, S | 1 |
| Kim, HJ; LeVieux, J; Liu, HW; Liu, YN; Mansoorabadi, SO; McCarty, RM; Ogasawara, Y | 1 |
| Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM | 1 |
| Benoist, JF; Blom, HJ; Imbard, A | 1 |
| Allen, KD; Wang, SC | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM | 1 |
| Brachet, P; Comte, B; Deval, C; Jousse, C; Martinez, E; Mazur, A | 1 |
| Augoustides-Savvopoulou, P; Baumgartner, MR; Blair, E; Brennerova, K; Broomfield, A; Bürer, C; De Meirleir, L; Fowler, B; Gökcay, G; Hennermann, J; Huemer, M; Jardine, P; Ješina, P; Koch, J; Kožich, V; Landolt, MA; Lorenzl, S; Lotz-Havla, AS; Noss, J; Parini, R; Peters, H; Plecko, B; Ramos, FJ; Schlune, A; Suormala, T; Tsiakas, K; Zerjav Tansek, M | 1 |
| Kroutil, W; Richter, N; Zepeck, F | 1 |
| Giedyk, M; Goliszewska, K; Gryko, D | 1 |
| Blaszczyk, AJ; Booker, SJ; Buller, AR; Grove, TL; Lloyd, EP; Marous, DR; Moshos, KA; Townsend, CA | 1 |
| Ding, W; Ji, X; Jia, Y; Li, Q; Qianzhu, H; Zhang, Q | 1 |
| Deth, R; Hodgson, N; Trivedi, M; Zhang, Y | 1 |
| Blanco, R; Colombo, A; Pardo, R; Suazo, J | 1 |
| Bandeira, A; Baumgartner, MR; Benoist, JF; Blom, H; Burlina, A; Cerone, R; Couce, ML; Diodato, D; Dionisi-Vici, C; Garcia-Cazorla, A; Huemer, M; Kožich, V; la Marca, G; Pasquini, E; Schiff, M; Schwahn, B; Vilarinho, L; Weisfeld-Adams, JD | 1 |
| Benjdia, A; Berteau, O; Chartier, G; Guillot, A; Leprince, J; Parent, A | 1 |
| Eguchi, T; Kim, SY; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Couce, ML; Llarena, M; López-Suárez, O | 1 |
| Blaszczyk, AJ; Booker, SJ; Ho, JV; Silakov, A; Wang, B | 1 |
| Blaszczyk, AJ; Booker, SJ; Wang, RX | 1 |
| Kim, HJ; Liu, HW; Liu, YN; McCarty, RM | 1 |
| Eguchi, T; Hammerschmidt, F; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| McLaughlin, MI; van der Donk, WA | 1 |
| Alberto, JM; Battaglia-Hsu, SF; Coelho, D; Dreumont, N; Gauchotte, G; Ghemrawi, R; Guéant, JL; Hergalant, S; Houlgatte, R; Jung, M; Mosca, P; Ndiongue, M; Paoli, J; Quadros, EV; Robert, A; Sequeira, JM; Umoret, R | 1 |
| Blaesi, EJ; Blaszczyk, AJ; Booker, SJ; Knox, HL; Krebs, C; Wang, B; Wang, RX; Zhou, S | 1 |
| Fry, RC; Gamble, MV; Garcia-Vargas, G; Herring, AH; Ilievski, V; Laine, JE; Richardson, DB; Rubio-Andrade, M; Stýblo, M | 1 |
| Wang, SC | 1 |
| Begley, TP; Müller, R; Schnell, B; Wang, Y | 1 |
| Baethmann, M; Ballhausen, D; Baumgartner, MR; Blasco-Alonso, J; Blom, H; Boy, N; Bueno, M; Burgos Peláez, R; Cerone, R; Chabrol, B; Chapman, KA; Couce, ML; Crushell, E; Dalmau Serra, J; Diodato, D; Diogo, L; Dionisi-Vici, C; Ficicioglu, C; Froese, DS; García Jimenez, MC; García Silva, MT; Gaspar, AM; Gautschi, M; Gleich, F; González-Lamuño, D; Gouveia, S; Grünewald, S; Hendriksz, C; Huemer, M; Janssen, MCH; Jesina, P; Koch, J; Kölker, S; Konstantopoulou, V; Kožich, V; Lavigne, C; Lund, AM; Martin, CA; Martinelli, D; Martins, EG; Meavilla Olivas, S; Mention, K; Mochel, F; Morris, AA; Mundy, H; Murphy, E; Olivieri, G; Paquay, S; Pedrón-Giner, C; Ruiz Gómez, MA; Santra, S; Schiff, M; Scholl-Bürgi, S; Schwartz, IV; Seifert, B; Servais, A; Skouma, A; Tran, C; Vives Piñera, I; Walter, J; Weisfeld-Adams, J | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R | 1 |
| Booker, SJ; Laremore, TN; Miller, DV; Radle, MI | 1 |
| Belardo, A; Gevi, F; Zolla, L | 1 |
| Blaszczyk, AJ; Booker, SJ; Knox, HL | 1 |
| Jarrett, JT | 1 |
| DiNicolantonio, JJ; McCarty, MF; O'Keefe, JH | 1 |
| Ao, PL; Chung, CJ; Hsieh, RL; Hsueh, YM; Huang, PT; Huang, SR; Huang, YL; Lin, MI; Lin, YC; Mu, SC; Shiue, HS; Su, CT; Wu, MY | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Julien, A; Pourié, G; Robert, A; Saber Cherif, L; Umoret, R | 1 |
| Li, R; Lichstrahl, MS; Marous, DR; Sinner, EK; Townsend, CA | 1 |
| Browne, RW; Desai, G; Kordas, K; Mañay, N; Millen, AE; Peregalli, F; Queirolo, EI; Vahter, M; Yu, J | 2 |
| Elías-Arnanz, M | 1 |
| Adrian, L; Deobald, D; Hanna, R; Layer, G; Shahryari, S | 1 |
| Bouvier, D; Brailova, M; Minet-Quinard, R; Regnier, A; Sapin, V; Szymanowski, M | 1 |
| Blaszczyk, AJ; Booker, SJ; Chen, PY; Drennan, CL; Grove, TL; Knox, HL; Mukherjee, A; Schwalm, EL; Wang, B | 1 |
| Edwards, S; Ghosh, AP; Jaroszynska-Wolinska, J; Kozlowski, PM; Malinowski, S | 1 |
| Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
| Hammerschmidt, F; McLaughlin, MI; Pallitsch, K; van der Donk, WA; Wallner, G | 1 |
| Benjdia, A; Bernardo-García, N; Berteau, O; Brewee, C; Chavas, LMG; Fradale, L; Fyfe, CD; Grimaldi, S; Guillot, A; Legrand, P | 1 |
| Boal, AK; Booker, SJ; Knox, HL; Sinner, EK; Townsend, CA | 1 |
| Benjdia, A; Berteau, O; Brewee, C; Guillot, A; Guinchard, X; Haumann, M; Kubiak, X; Sabat, N; Soualmia, F | 1 |
| Drennan, CL; Ulrich, EC | 1 |
| Andexer, JN; Friedrich, T; Gagsteiger, J; Gericke, L; Heidinger, L; Jahn, S; Layer, G; Loenarz, C | 1 |
| Bommarito, P; Clark, J; Fry, RC; Gamble, MV; García-Vargas, GG; Rubio-Andrade, M; Stýblo, M | 1 |
| Eguchi, T; Hamano, Y; Hashimoto, J; Kozone, I; Kudo, F; Maruyama, C; Minato, A; Nagano, N; Sato, S; Shin-Ya, K | 1 |
37 review(s) available for isomethyleugenol and vitamin b 12
| Article | Year |
|---|---|
Mechanisms for the biomethylation of metals and metalloids.
Topics: Alkylmercury Compounds; Arsenic; Carbazoles; Cell Membrane Permeability; Metals; Methylation; Methylmercury Compounds; Organometallic Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyrenes; S-Adenosylmethionine; Spectrometry, Fluorescence; Tetrahydrofolates; Vitamin B 12 | 1978 |
Cobalamin deficiency and the pathogenesis of nervous system disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Humans; Methylation; Methylmalonyl-CoA Mutase; Nervous System Diseases; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
The biosynthesis of porphyrins, chlorophylls, and vitamin B12.
Topics: 5-Aminolevulinate Synthetase; Animals; Bacteriochlorophylls; Biotransformation; Chlorophyll; Coproporphyrinogen Oxidase; Cytochromes; Ferrochelatase; Heme; Hydroxymethylbilane Synthase; Magnesium; Magnetic Resonance Spectroscopy; Methylation; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Plants; Porphobilinogen Synthase; Porphyrins; Protoporphyrinogen Oxidase; Pyrroles; Uroporphyrinogen Decarboxylase; Vinyl Compounds; Vitamin B 12 | 1985 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
[Control of cellular division by vitamin B 12 and folates].
Topics: Anemia, Macrocytic; Anemia, Pernicious; Animals; Cell Division; Euglena gracilis; Folic Acid; Folic Acid Deficiency; Humans; Leukemia; Methylation; Nucleic Acids; Nucleotides; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Mechanisms for synthesis of organic mercury found in fish.
Topics: Animals; Biotransformation; Chlorides; Fishes; Humans; Mercury; Mercury Poisoning; Methionine; Methylation; Methylmercury Compounds; Neurospora crassa; Organometallic Compounds; Vitamin B 12 | 1972 |
[Total synthesis of vitamin B12].
Topics: Alkylation; Amides; Chemical Phenomena; Chemistry; Choline; Methylation; Photochemistry; Porphyrins; Vitamin B 12 | 1974 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Vitamin B12, folate and nitrous oxide.
Topics: Anemia, Megaloblastic; Animals; Deoxyuridine; Folic Acid; Formates; Hematopoiesis; Humans; Methylation; Nitrous Oxide; Vitamin B 12 | 1982 |
Nitrous oxide and the cobalamins.
Topics: Anesthesia, Inhalation; Animals; Chemical Phenomena; Chemistry; Coenzymes; Deoxyuridine; Folic Acid; Humans; Liver; Methylation; Nervous System; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Vitamin B 12 | 1980 |
Binding site revealed of nature's most beautiful cofactor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Escherichia coli; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1994 |
How nature builds the pigments of life: the conquest of vitamin B12.
Topics: Cobalt; Genes, Bacterial; Methylation; Oxidation-Reduction; Propionibacterium; Uroporphyrins; Vitamin B 12 | 1994 |
Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Blood Coagulation Factors; Blood Platelets; Child; Cystathionine beta-Synthase; Endothelium, Vascular; Fibrinolytic Agents; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Penicillamine; Risk Factors; Thrombosis; Vascular Diseases; Vitamin B 12; Vitamin B 6 Deficiency; Vitamins | 1993 |
Biochemical pathogenesis of subacute combined degeneration of the spinal cord and brain.
Topics: Brain Diseases; Demyelinating Diseases; Humans; Metabolism, Inborn Errors; Methylation; Nerve Degeneration; Spinal Cord Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Folate, vitamin B12, and neuropsychiatric disorders.
Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Enzyme-catalyzed methyl transfers to thiols: the role of zinc.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Archaea; Catalysis; Dimethylallyltranstransferase; Homocysteine; Methylation; Sulfhydryl Compounds; Vitamin B 12; Zinc | 1997 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
AIDS-associated vacuolar myelopathy.
Topics: Diagnosis, Differential; Disease Progression; HIV Infections; Humans; Male; Methylation; Muscular Atrophy, Spinal; Parasympatholytics; Physical Therapy Modalities; Vitamin B 12 | 1998 |
Metabolic consequences of hyperhomocysteinemia in uremia.
Topics: Cardiovascular Diseases; Female; Glomerular Filtration Rate; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylation; Renal Dialysis; Risk Factors; Sex Factors; Uremia; Vitamin B 12; Vitamin B 6 | 2001 |
Methods for measuring sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Methionine; Methylation; Models, Biological; Radioisotope Dilution Technique; Vitamin B 12 | 2002 |
Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations.
Topics: Adenoma; Alcohol Drinking; Colonic Neoplasms; Folic Acid; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Neoplasms; Nutrition Policy; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12 | 2003 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Fine-tuning our knowledge of the anaerobic route to cobalamin (vitamin B12).
Topics: Amidohydrolases; Anaerobiosis; Bacteria; Bacterial Proteins; Carboxy-Lyases; Cobalt; Methylation; Methyltransferases; Uroporphyrins; Vitamin B 12 | 2006 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
Nitrous oxide-induced B₁₂ deficiency myelopathy: Perspectives on the clinical biochemistry of vitamin B₁₂.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cobamides; Cytokines; Folic Acid; Gait Ataxia; Humans; Illicit Drugs; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Imaging; Male; Methylation; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Models, Animal; Models, Biological; Nitrous Oxide; Postgastrectomy Syndromes; Pyramidal Tracts; Spinal Cord; Subacute Combined Degeneration; Substance-Related Disorders; Vitamin B 12; Young Adult | 2011 |
Radical-mediated enzymatic methylation: a tale of two SAMS.
Topics: Free Radicals; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2012 |
The role of B vitamins in preventing and treating cognitive impairment and decline.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Role of heat-shock proteins and cobalamine in maintaining methionine synthase activity.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Heat-Shock Proteins; Homocysteine; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; Plaque, Atherosclerotic; Vitamin B 12 | 2012 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
Vitamin B12 catalysed reactions.
Topics: Alkenes; Catalysis; Cobalt; Hydrogenation; Methylation; Models, Molecular; Oxidation-Reduction; Vitamin B 12 | 2015 |
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis.
Topics: Biomarkers; Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Vitamin B 12 | 2016 |
Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency.
Topics: Animals; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Proto-Oncogene Proteins c-cbl; Vitamin B 12 | 2017 |
Cobalamin-dependent radical S-adenosyl-l-methionine enzymes in natural product biosynthesis.
Topics: Adenine; Aminobutyrates; Biological Products; Enzymes; Fosfomycin; Gentamicins; Methylation; S-Adenosylmethionine; Shewanella; Thiostrepton; Vitamin B 12 | 2018 |
6 trial(s) available for isomethyleugenol and vitamin b 12
| Article | Year |
|---|---|
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Randomized trial of methylcobalamin and folate effects on homocysteine in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2002 |
Treatment of multiple sclerosis with lofepramine, L-phenylalanine and vitamin B(12): mechanism of action and clinical importance: roles of the locus coeruleus and central noradrenergic systems.
Topics: Adrenergic Fibers; Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Fatigue Syndrome, Chronic; Humans; Locus Coeruleus; Lofepramine; Methylation; Multiple Sclerosis; Norepinephrine; Pain; Phenylalanine; Severity of Illness Index; Stroke; Stroke Rehabilitation; Tegmentum Mesencephali; Treatment Outcome; Vitamin B 12 | 2002 |
Can black tea influence plasma total homocysteine concentrations?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cholesterol; Cross-Over Studies; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Lipids; Male; Methylation; Middle Aged; Phenols; Polymers; Polyphenols; Tea; Vitamin B 12; Vitamin B 6 | 2003 |
A proteomics study reveals a predominant change in MaoB expression in platelets of healthy volunteers after high protein meat diet: relationship to the methylation cycle.
Topics: Adult; Blood Platelets; Cognition; Electrophoresis, Gel, Two-Dimensional; Fasting; Food, Fortified; Homocysteine; Humans; Male; Methylation; Monoamine Oxidase; Neuropsychological Tests; Proteins; Proteomics; Psychomotor Performance; Reaction Time; Single-Blind Method; Statistics as Topic; Statistics, Nonparametric; Up-Regulation; Vitamin B 12; Young Adult | 2011 |
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine.
Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
249 other study(ies) available for isomethyleugenol and vitamin b 12
| Article | Year |
|---|---|
Methylation by diastereoisomers of methylcobalamin.
Topics: Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Kinetics; Methylation; Methylmercury Compounds; Salts; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12 | 1976 |
Stereochemical studies of enzymic C-methylations.
Topics: Enzymes; Magnetic Resonance Spectroscopy; Methionine; Methylation; S-Adenosylmethionine; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12 | 1977 |
Coenzyme M and methylcobalamin in methane biosynthesis: results of model studies.
Topics: Bacteria; Mercaptoethanol; Mesna; Methane; Methylation; Oxidation-Reduction; Oximes; Structure-Activity Relationship; Vitamin B 12 | 1978 |
[Role of the components in the methylation system in the cobalamin-dependent gentamycin biosynthesis by a Micromonospora purpurea culture].
Topics: Cobalt; Culture Media; Dose-Response Relationship, Drug; Gentamicins; Methionine; Methylation; Micromonospora; Vitamin B 12 | 1979 |
Biosynthesis of porphyrins and related macrocycles. Part 9. Biosynthesis of the corrin macrocycle of vitamin B12 including the sterochemistry of C-methylation in ring.
Topics: Methylation; Porphyrins; Propionibacterium; Stereoisomerism; Vitamin B 12 | 1977 |
Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfer
Topics: Methylation; Porphyrinogens; Porphyrins; Propionibacterium; Uroporphyrinogens; Vitamin B 12 | 1977 |
Formation and accumulation of methylmercury in organisms.
Topics: Animals; Bacteria; Fishes; Methylation; Methylmercury Compounds; Vitamin B 12 | 1977 |
The biochemistry of toxic elements.
Topics: Biotransformation; Humans; Lead; Metals; Methylation; Organometallic Compounds; Platinum; Tin; Vitamin B 12 | 1978 |
Effects of surfactants on cobalamin dependent methyl transfer. Influence of aqueous and reversed micelles on the interaction of mercuric ion with methylcobalamin.
Topics: Mathematics; Mercury; Methylation; Solvents; Surface-Active Agents; Vitamin B 12; Water | 1977 |
Biomethylation of toxic elements in the environment.
Topics: Arsenic; Biotransformation; Chemical Phenomena; Chemistry; Iron; Lead; Mercury; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Tin; Vitamin B 12 | 1977 |
Methylation of chloroplatinate by methylcobalamin.
Topics: Indicators and Reagents; Magnetic Resonance Spectroscopy; Methylation; Platinum; Vitamin B 12 | 1976 |
Gastric secretory inhibition by two 16-methylated analogs of prostaglandin E2 given intragastrically to patients with duodenal ulcer disease.
Topics: Adult; Cobalt Radioisotopes; Depression, Chemical; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Juice; Humans; Male; Methylation; Middle Aged; Pepsin A; Prostaglandins; Secretory Rate; Stimulation, Chemical; Vitamin B 12 | 1975 |
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1975 |
Formation of methyl mercury by bacteria.
Topics: Bacillus; Bacteria; Enterobacter; Escherichia; Homocysteine; Mercury; Methylation; Oxygen; R Factors; Soil Microbiology; Staphylococcus; Stereoisomerism; Streptococcus; Vitamin B 12; Water Microbiology | 1975 |
Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin.
Topics: Fosfomycin; Methylation; Molecular Structure; Proteus; Streptomyces; Vitamin B 12 | 1992 |
Biosynthesis of vitamin B12 in anaerobic bacteria. Experiments with Eubacterium limosum on the incorporation of D-[1-13C]erythrose and [13C]formate into the 5,6-dimethylbenzimidazole moiety.
Topics: Benzimidazoles; Carbon Isotopes; Eubacterium; Formates; Magnetic Resonance Spectroscopy; Methylation; Tetroses; Vitamin B 12 | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Crystallization and preliminary X-ray diffraction studies of the cobalamin-binding domain of methionine synthase from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Crystallization; Escherichia coli; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Vitamin B 12; X-Ray Diffraction | 1992 |
Methylation of DNA in megaloblastic anaemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Blotting, Southern; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Probes; Humans; Methylation; Vitamin B 12 | 1990 |
Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product.
Topics: Amino Acid Sequence; Bacterial Proteins; Decarboxylation; Genes, Bacterial; Methylation; Molecular Sequence Data; Pseudomonas; Uroporphyrins; Vitamin B 12 | 1992 |
Effect of cobalamin derivatives on in vitro enzymatic DNA methylation: methylcobalamin can act as a methyl donor.
Topics: Animals; DNA; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spleen; Vitamin B 12 | 1991 |
Acetate-dependent methylation of two corrinoid proteins in extracts of Methanosarcina barkeri.
Topics: Acetates; Chromatography, Gas; Chromatography, High Pressure Liquid; Corrinoids; Electrophoresis, Polyacrylamide Gel; Euryarchaeota; Methylation; Spectrophotometry, Ultraviolet; Vitamin B 12 | 1991 |
DNA-repair capacity and lipid peroxidation in chronic alcoholics.
Topics: Adult; Alcoholism; Ascorbic Acid; Cells, Cultured; DNA; DNA Repair; Humans; Lipid Peroxidation; Male; Methylation; Methylnitrosourea; Middle Aged; Regression Analysis; Vitamin A; Vitamin B 12; Vitamin E | 1991 |
Biosynthesis of vitamin B12: isolation of precorrin-6x, a metal-free precursor of the corrin macrocycle retaining five S-adenosylmethionine-derived peripheral methyl groups.
Topics: Magnetic Resonance Spectroscopy; Methylation; NADP; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1990 |
Biosynthesis of vitamin B12: structure of precorrin-6x octamethyl ester.
Topics: Cell-Free System; Esters; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Pseudomonas; Uroporphyrins; Vitamin B 12 | 1990 |
A relationship between vitamin B12, folic acid, ascorbic acid, and mercury uptake and methylation.
Topics: Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Eating; Folic Acid; Guinea Pigs; Mercury; Methylation; Nutritional Requirements; Organ Specificity; Pilot Projects; Rats; Vitamin B 12 | 1990 |
Enzymatic synthesis of dihydrosirohydrochlorin (precorrin-2) and of a novel pyrrocorphin by uroporphyrinogen III methylase.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Escherichia coli; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Structure; Porphyrins; Spectrophotometry; Uroporphyrins; Vitamin B 12 | 1990 |
Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.
Topics: Animals; Arginine; Brain Diseases; Chiroptera; Cycloleucine; Disease Models, Animal; Liver; Methylation; Myelin Basic Protein; Rats; Rats, Inbred Strains; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Spectroelectrochemical studies of the corrinoid/iron-sulfur protein involved in acetyl coenzyme A synthesis by Clostridium thermoaceticum.
Topics: Acetyl Coenzyme A; Clostridium; Cobalt; Corrinoids; Electrochemistry; Iron-Sulfur Proteins; Metalloproteins; Methylation; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Vitamin B 12 | 1989 |
Cobalamin-dependent methionine synthase from Escherichia coli B: electron paramagnetic resonance spectra of the inactive form and the active methylated form of the enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electron Spin Resonance Spectroscopy; Escherichia coli; Methylation; Methyltransferases; Molecular Weight; Oxidation-Reduction; S-Adenosylmethionine; Vitamin B 12 | 1988 |
Methyl transfer from methylcobalamin to thiols. A reinvestigation.
Topics: Anaerobiosis; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methylation; Spectrophotometry; Sulfhydryl Compounds; Vitamin B 12 | 1985 |
[Effect of vitamin B12 on carnitine synthesis in the body of rats].
Topics: Aging; Animals; Carnitine; Liver; Male; Methylation; Rats; Vitamin B 12 | 1988 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
Biosynthesis of vitamin B-12 in anaerobic bacteria. Experiments with Eubacterium limosum on the origin of the amide groups of the corrin ring and of N-3 of the 5,6-dimethylbenzimidazole part.
Topics: Amides; Anaerobiosis; Benzimidazoles; Corrinoids; Eubacterium; Fermentation; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Vitamin B 12 | 1988 |
NMR studies of biosynthetic pathways.
Topics: Bacteria; Binding Sites; Carbon Isotopes; Chlorophyll; Clostridium; Corrinoids; Enzymes; Freezing; Heme; Magnetic Resonance Spectroscopy; Methylation; Propionibacterium; Protein Binding; Vitamin B 12 | 1986 |
Study of inorganic arsenic methylation by rat liver in vitro: relevance for the interpretation of observations in man.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Coenzymes; Cytosol; Enzyme Inhibitors; Glutathione; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1985 |
A simplified assay for coenzyme M (HSCH2CH2SO3). Resolution of methylcobalamin-coenzyme M methyltransferase and use of sodium borohydride.
Topics: Bacteria; Borohydrides; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Coenzymes; Electrophoresis, Paper; Kinetics; Manganese; Methylation; Methyltransferases; NADP; Oxidation-Reduction; Spectrophotometry; Sulfhydryl Compounds; Sulfonic Acids; Time Factors; Vitamin B 12 | 1974 |
Escherichia coli B cobalamin methyltransferase: ability of diaphorases and lipoamide dehydrogenases to function as reducing agents.
Topics: Alcohols; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Iodoacetates; Methionine; Methylation; Myocardium; NAD; Spectrophotometry; Sulfhydryl Compounds; Swine; Transferases; Vitamin B 12 | 1970 |
Synthesis and catalytic activity of spin-labeled cobinamide coenzymes.
Topics: Acetaldehyde; Amino Alcohols; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Circular Dichroism; Coenzymes; Cyclic N-Oxides; Deoxyadenosines; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Methylation; Models, Structural; Photolysis; Piperidines; Quaternary Ammonium Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 1971 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
[On the coordination isomerism of Co-methylcobalamin].
Topics: Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Hydrogen-Ion Concentration; Methylation; Stereoisomerism; Vitamin B 12 | 1968 |
[On the coordination isomerism (a-b isomerism) of Co-alkyl corrinoids. Partial synthesis and some properties of Co-methyl-cobalamin a].
Topics: Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Cyanides; Electrophoresis; Hydrogen-Ion Concentration; Iodides; Methylation; Stereoisomerism; Vitamin B 12 | 1969 |
[Coordination isomery of cobalt-methyl derivatives of cobyric acid and cobinamide-monocarbonic acids].
Topics: Carbonates; Methylation; Vitamin B 12 | 1970 |
[Coordination-isomery of cobalt-methyl-factor I b and cobalt-methyl-cobalamine].
Topics: Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cobalt; Methylation; Spectrum Analysis; Stereoisomerism; Vitamin B 12; Water | 1970 |
Biosynthesis of 5,6-dimethylbenzimidazole. Precursor-function of 6,7-dimethyl-8-ribityllumazine.
Topics: Aerobiosis; Anaerobiosis; Benzimidazoles; Carbon; Carbon Isotopes; Hydrolysis; Methylation; Propionibacterium; Pteridines; Riboflavin; Ribose; Vitamin B 12 | 1971 |
[The reduction of the B 12 -vitamins by carbon monoxide].
Topics: Benzimidazoles; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Kinetics; Lactams; Methanol; Methylation; Oxidation-Reduction; Spectrophotometry; Vitamin B 12 | 1972 |
In vitro studies on the effect of hydrazine on the morphogenesis of chick embryos and the mechanism of its action.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Brain; Chick Embryo; Culture Techniques; Folic Acid; Heart; Hydrazines; Methylation; Morphogenesis; Vitamin B 12 | 1974 |
Methionine and vitamin B 12 repression and precursor induction in the regulation of homocysteine methylation in Salmonella typhimurium.
Topics: Apoproteins; Chloramphenicol; Enzyme Induction; Enzyme Precursors; Genes, Regulator; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Oxidoreductases; Salmonella typhimurium; Tetrahydrofolates; Vitamin B 12 | 1973 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: circular dichroism of the methylated and propylated holoenzymes.
Topics: 1-Propanol; Alcohols; Benzyl Compounds; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Circular Dichroism; Escherichia coli; Ethanol; Hydrogen-Ion Concentration; Methionine; Methylation; Methyltransferases; Protein Binding; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Vitamin B 12 | 1973 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
[Effect of ATP, ADP and AMP on the formation of methane from methylcobalamin by cell-free extracts of Methanobacillus kuzneceovii].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacteria; Cell-Free System; Methane; Methylation; Vitamin B 12 | 1972 |
[Studies on vitamin B 12 -dependent reactions in Ascaris suum].
Topics: Animals; Ascaris; Cobamides; Coenzyme A; Female; Isomerases; Ligands; Malonates; Methylation; Methyltransferases; Ovary; RNA; RNA, Transfer; S-Adenosylmethionine; Vitamin B 12 | 1972 |
Schildt B, Sörbo B,+SORBO B:Studies on the biosynthesis and transfer of labile methyl groups in experimental burns.
Topics: Animals; Burns; Choline; Folic Acid; Liver; Methionine; Methylation; Mice; Vitamin B 12 | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Biological methylation. Its nature and scope.
Topics: Bacteria; Half-Life; Mercury; Methylation; Methylmercury Compounds; Organometallic Compounds; Vitamin B 12 | 1973 |
The kinetics and mechanism of cobalamin-dependent methyl and ethyl transfer to mercuric ion.
Topics: Acetates; Alkylation; Chemical Phenomena; Chemistry; Cobamides; Coenzymes; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mercury; Methylation; Spectrophotometry; Tritium; Vitamin B 12 | 1973 |
Total synthesis of acetate from CO2. VII. Evidence with Clostridium thermoaceticum that the carboxyl of acetate is derived from the carboxyl of pyruvate by transcarboxylation and not by fixation of CO2.
Topics: Acetates; Butyrates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Clostridium; Ferredoxins; Isotope Labeling; Keto Acids; Kinetics; Methylation; Oxidation-Reduction; Oxidoreductases; Pyruvates; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1973 |
Stereochemistry of methyl group insertion in corrinoid biosynthesis. Determination of carbon isotope chirality by 13C nuclear magnetic resonance.
Topics: Carbon Isotopes; Magnetic Resonance Spectroscopy; Methylation; Porphyrins; Propionibacterium; S-Adenosylmethionine; Stereoisomerism; Vitamin B 12 | 1973 |
Histidine catabolism in iron-deficient rats.
Topics: Anemia, Hypochromic; Animals; Blood Proteins; FIGLU Test; Hemoglobins; Histidine; Homocysteine; Iron; Liver; Male; Methylation; Rats; Transferases; Vitamin B 12 | 1973 |
Acetylation and methylation of histones in pernicious anemia.
Topics: Acetylation; Amino Acids; Anemia, Pernicious; Bone Marrow Examination; Electrophoresis, Paper; Erythropoiesis; Histones; Humans; Lysine; Methionine; Methylation; Tritium; Vitamin B 12 | 1974 |
Enzymic synthesis of methionine: formation of a radioactive cobamide enzyme with N5-methyl-14C-tetrahydrofolate.
Topics: Carbon Isotopes; Catalysis; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Kinetics; Methionine; Methylation; Transferases; Vitamin B 12 | 1967 |
[Reaction rate of methionine synthesis in Escherichia coli].
Topics: Binding Sites; Carbon Isotopes; Cellulose; Centrifugation, Zonal; Chemical Precipitation; Chromatography, Gel; Coenzymes; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Ligases; Methionine; Methylation; Models, Biological; Molecular Weight; Protein Binding; Radiation Effects; Tritium; Vitamin B 12 | 1967 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine methyltransferase: sequential formation of bound methylcobalamin with S-adenosyl-L-methionine and N5-methyltetrahydrofolate.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Light; Methionine; Methylation; Nucleosides; Temperature; Time Factors; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: activation with S-adenosyl-L-methionine and the mechanism for methyl group transfer.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Models, Biological; Nucleosides; Time Factors; Transferases; Vitamin B 12 | 1969 |
On the role of S-adenoxylmethionine in the vitamin B12 dependent methionine biosynthesis.
Topics: Alcohols; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxyapatites; Kinetics; Methionine; Methods; Methylation; Nucleosides; Spectrophotometry; Sulfur; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: resolution and reconstitution of holoenzyme.
Topics: Alcohols; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Darkness; Escherichia coli; Homocysteine; Light; Methionine; Methylation; Nucleosides; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Sulfur; Tetroses; Transferases; Tritium; Ultracentrifugation; Urea; Vibration; Vitamin B 12 | 1970 |
Spectrophotometric evidence for the formation of an Escherichia coli B B-12s methyltransferase.
Topics: Alcohols; Carbon Isotopes; Escherichia coli; Folic Acid; Free Radicals; Homocysteine; Hydrogen-Ion Concentration; Iodides; Ligases; Methionine; Methylation; Oxidation-Reduction; Spectrophotometry; Sulfur; Transferases; Ultraviolet Rays; Vitamin B 12 | 1970 |
Methylation of mercury compounds by methylcobalamin.
Topics: Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gas; Escherichia coli; Homocysteine; Hydroxides; Hydroxocobalamin; Kinetics; Mercaptoethanol; Mercury; Mercury Poisoning; Methylation; Organometallic Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 1971 |
The vitamin B12-dependent methionine synthetase. The cycle of transmethylation.
Topics: Enzyme Induction; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; Nucleosides; Oxidation-Reduction; Spectrophotometry; Transferases; Vitamin B 12 | 1971 |
Synthesis of specific transfer ribonucleic acids during methionine starvation in Escherichia coli 113-3.
Topics: Carbon Isotopes; Chromatography; Escherichia coli; Ligases; Methionine; Methylation; Mutation; Protein Biosynthesis; RNA, Bacterial; RNA, Transfer; Tritium; Valine; Vitamin B 12 | 1971 |
Methylcobalamin as a substrate at a separate site on Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase.
Topics: Alkylation; Binding Sites; Carbon Isotopes; Catalysis; Coenzymes; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Temperature; Tritium; Urea; Vitamin B 12 | 1971 |
Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.
Topics: Alkylation; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dithiothreitol; Drug Stability; Escherichia coli; Folic Acid; Homocysteine; Hydroxocobalamin; Macromolecular Substances; Mathematics; Methylation; Methyltransferases; Molecular Weight; Tritium; Urea; Vitamin B 12 | 1971 |
Transductional analysis of Pseudomonas aeruginosa methionineless auxotrophs.
Topics: Cysteine; Genetics, Microbial; Homocysteine; Methionine; Methylation; Mutation; Pseudomonas aeruginosa; Transduction, Genetic; Vitamin B 12 | 1969 |
Biosynthesis of 5,6-dimethylbenzimidazole from (1'- 14 C,5- 15 N)6,7-dimethyl-8-ribityllumazine.
Topics: Aerobiosis; Benzimidazoles; Carbon Isotopes; Chromatography, Gas; Isotope Labeling; Mass Spectrometry; Methylation; Nitrogen Isotopes; Propionibacterium; Pteridines; Vitamin B 12 | 1972 |
Coenzyme B 12 dependent propanediol dehydratase system. Nature of cobalamin binding and some properties of apoenzyme-coenzyme B 12 analog complexes.
Topics: Apoproteins; Chloromercuribenzoates; Chromatography, Gel; Cobamides; Coenzymes; Cyanides; Dithiothreitol; Drug Stability; Enterobacter; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxocobalamin; Methylation; Potassium; Propylene Glycols; Protein Binding; Spectrophotometry; Urea; Vitamin B 12 | 1972 |
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Carbon Isotopes; Coenzymes; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Methionine; Methylation; Methyltransferases; Oxidoreductases; Vitamin B 12 | 1972 |
Biosynthesis of corrinoids. Concerning ithe origin of the methyl groups in vitamin B 12 .
Topics: Carbon Isotopes; Methylation; Propionibacterium; Vitamin B 12 | 1972 |
Mass spectrometry studies of substituted methanes formed from deutero- and fluoromethylcobalamins.
Topics: Bacteria; Chromatography, Gas; Cobamides; Coenzymes; Deuterium; Kinetics; Mass Spectrometry; Methane; Methylation; Photolysis; Tritium; Vitamin B 12 | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |
Recent advances in the chemistry of natural products.
Topics: Cobalt; Ethers, Cyclic; Methods; Methylation; Stereoisomerism; Vitamin B 12 | 1971 |
Transport of vitamin B 12 in Ochromonas malhamensis.
Topics: Binding Sites; Biological Transport; Biological Transport, Active; Calcium Chloride; Chlorides; Cobalt Isotopes; Coenzymes; Cyanides; Dinitrophenols; Eukaryota; Fluorides; Hydrogen-Ion Concentration; Kinetics; Mercury; Methylation; Potassium; Sodium; Temperature; Vitamin B 12 | 1971 |
Methyl transfer from methyl vitamin B 12 .
Topics: Air; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Hydroxocobalamin; Kinetics; Mathematics; Mercaptoethanol; Methylation; Nitrogen; Oxidation-Reduction; Oxygen; Spectrophotometry; Vitamin B 12 | 1971 |
Total synthesis of acetate from CO2. 3. Inhibition by alkylhalides of the synthesis from CO2, methyltetrahydrofolate, and methyl-B12 by Clostridium thermoaceticum.
Topics: Acetates; Alkylation; Butyrates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Chloroform; Clostridium; Coenzymes; Darkness; Depression, Chemical; Enzyme Activation; Fermentation; Folic Acid; Glucose; Hydrocarbons, Halogenated; Iodine; Iron; Keto Acids; Kinetics; Light; Methylation; Photolysis; Pyruvates; Quaternary Ammonium Compounds; Radiation Effects; Sulfates; Time Factors; Vitamin B 12 | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Propanediol dehydratase system. Role of monovalent cations in binding of vitamin B 12 coenzyme or its analogs to apoenzyme.
Topics: Binding Sites; Cesium; Chemical Phenomena; Chemistry, Physical; Chloromercuribenzoates; Chromatography, Gel; Coenzymes; Deoxyadenosines; Enterobacter; Enzyme Activation; Ethylamines; Hydro-Lyases; Hydroxocobalamin; Kinetics; Lithium; Mathematics; Methylamines; Methylation; Models, Biological; Oxygen; Phosphates; Potassium Chloride; Propylene Glycols; Protein Binding; Quaternary Ammonium Compounds; Rubidium; Sodium; Spectrophotometry; Tromethamine; Vitamin B 12 | 1971 |
Defective metabolism of vitamin B 12 in fibroblasts from children with methylmalonicaciduria.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cobalt Isotopes; Deoxyadenosines; Enzyme Activation; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Malonates; Metabolism, Inborn Errors; Methylation; Methyltransferases; Vitamin B 12 | 1971 |
Biochemical studies on Streptomyces aureofaciens. V. The role of cobalamins and methionine in methylation reactions in tetracycline biosynthesis.
Topics: Adenine; Carbon Isotopes; Cobalt; Glycine; Methionine; Methylation; Serine; Streptomyces; Tetracycline; Vitamin B 12 | 1969 |
[The coenzyme of vit. B 12. Biochemical and physiopathological significance].
Topics: Coenzymes; Methylation; Protein Biosynthesis; Vitamin B 12 | 1969 |
Methylcobalamin as an intermediate in mammalian methionine biosynthesis.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Electrophoresis; Ethanol; Folic Acid; Homocysteine; Kidney; Methionine; Methylation; Nucleosides; Photochemistry; Solubility; Swine; Transferases; Vitamin B 12 | 1970 |
Hydrocarbon-utilizing microorganism. Relationship of fatty acid composition and biosynthesis to hydrocarbon substrate and to vitamin B 12 level in Corynebacterium simplex.
Topics: Alkanes; Carbon Isotopes; Cobalt; Corynebacterium; Culture Media; Fatty Acids; Folic Acid; Homocysteine; Methionine; Methylation; Nucleosides; Spectrum Analysis; Transferases; Vitamin B 12 | 1970 |
Chemical methylation of inorganic mercury with methylcobalamin, a vitamin B12 analog.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Mercury; Methylation; Vitamin B 12; Water Pollution, Chemical | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
[The role of vitamin B12 in metabolism].
Topics: Animals; Coenzymes; Folic Acid; Homocysteine; Humans; Isomerases; Methylation; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Cobamide-dependent methanol-cyanocob(I)alamin methyltransferase of Methanosarcina barkeri.
Topics: Carbon Isotopes; Catalysis; Cellulose; Chromatography, Ion Exchange; Drug Stability; Ferredoxins; Hydrogen-Ion Concentration; Methane; Methanol; Methylation; Sarcina; Transferases; Vitamin B 12 | 1968 |
Synthesis of methyl-mercury compounds by extracts of a methanogenic bacterium.
Topics: Animals; Bacteria; Birds; Cobalt; Coenzymes; Industrial Waste; Japan; Legislation as Topic; Mercury; Mercury Poisoning; Methane; Methylation; Organometallic Compounds; Sewage; Sweden; Vitamin B 12; Water Pollution | 1968 |
Modification of protein synthesis by vitamin B12 in the marine algal flagellate Neochloris pseudoalveolaris.
Topics: Carbon Isotopes; Chloroplasts; DNA; Electrophoresis; Eukaryota; Leucine; Methionine; Methylation; Protein Biosynthesis; RNA; Tritium; Vitamin B 12 | 1969 |
The formation of methionine from the monoglutamate form of methyltetrahydrofolate by higher plants.
Topics: Acyltransferases; Carbon Isotopes; Chromatography, Gel; Folic Acid; Glutamates; Kinetics; Methionine; Methylation; Nucleosides; Plants; Vitamin B 12 | 1969 |
[The effect of conditions instrumental in the process of methylation on the biosynthesis of streptomycin by the Act. streptomycini LS-1 strain].
Topics: Betaine; Creatinine; Methionine; Methylation; Streptomyces; Streptomycin; Vitamin B 12; Vitamin B Complex | 1966 |
Methylation and mood.
Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency | 1984 |
Reductive activation of methanol: 5-hydroxybenzimidazolylcobamide methyltransferase of Methanosarcina barkeri.
Topics: Corrinoids; Enzyme Activation; Euryarchaeota; Ferredoxins; Hydrogenase; Methylation; Methyltransferases; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Vitamin B 12 | 1984 |
Involvement of mercury methylation in microbial mercury detoxication.
Topics: Clostridium; Inactivation, Metabolic; Mercuric Chloride; Mercury; Methylation; Methylmercury Compounds; Vitamin B 12 | 1982 |
Methyl transfer from methylcobalamin to diaquocobinamide.
Topics: Cobamides; Hydrogen-Ion Concentration; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Methylation; Vitamin B 12 | 1984 |
Effects of sea salt anions on the formation and stability of methylmercury.
Topics: Bicarbonates; Chlorides; Drug Stability; Methylation; Methylmercury Compounds; Seawater; Sulfides; Vitamin B 12 | 1983 |
[Effect of vitamin B12 on liver and kidney DNA methylation in guinea pigs in the presence of methionine and ATP].
Topics: 5-Methylcytosine; Adenosine Triphosphate; Animals; Cytosine; DNA; Drug Interactions; Guinea Pigs; Kidney; Liver; Male; Methionine; Methylation; Vitamin B 12 | 1983 |
[Changes in DNA methylation in guinea pig liver and kidney during vitamin B12 administration].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Guinea Pigs; Kidney; Liver; Male; Methylation; Vitamin B 12 | 1981 |
Biosynthetic incorporation of methyl groups into fortimicins.
Topics: Aminoglycosides; Anti-Bacterial Agents; Methionine; Methylation; Micromonospora; Vitamin B 12 | 1981 |
Plasmid-controlled mercury biotransformation by Clostridium cochlearium T-2.
Topics: Biotransformation; Clostridium; Hydrogen Sulfide; Mercury; Methylation; Methylmercury Compounds; Plasmids; Vitamin B 12 | 1980 |
Enhancement of adhesive property of epithelial cell line Mm2T by culture in the presence of methylated vitamin B12.
Topics: Animals; Cell Adhesion; Cell Communication; Cell Line; Epithelium; Methylation; Microscopy, Electron; Microscopy, Electron, Scanning; Vitamin B 12 | 1995 |
Homocysteinemia and schizophrenia as a case of methylation deficiency.
Topics: Adult; Female; Homocysteine; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1994 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
The energetics and sodium-ion dependence of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase studied with cob(I)alamin as methyl acceptor and methylcob(III)alamin as methyl donor.
Topics: Energy Metabolism; Methanobacterium; Methylation; Methyltransferases; Pterins; Sodium; Thermodynamics; Vitamin B 12 | 1994 |
O-demethylation by the homoacetogenic anaerobe Holophaga foetida studied by a new photometric methylation assay using electrochemically produced cob(I)alamin.
Topics: Anisoles; Electrochemistry; Gram-Negative Anaerobic Bacteria; Kinetics; Methylation; Oxidation-Reduction; Photometry; Tetrahydrofolates; Vanillic Acid; Vitamin B 12 | 1994 |
How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Isomerases; Amino Acid Sequence; Benzimidazoles; Catalysis; Computer Graphics; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Escherichia coli; Histidine; Intramolecular Transferases; Ligands; Methylation; Methylmalonyl-CoA Mutase; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Protein Structure, Secondary; Vitamin B 12 | 1994 |
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1994 |
Nitrous oxide degradation by cobalamin-dependent methionine synthase: characterization of the reactants and products in the inactivation reaction.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electrochemistry; Enzyme Activation; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Methionine; Methylation; Nitrous Oxide; Oxidation-Reduction; Oxygen; Spectrophotometry; Vitamin B 12 | 1994 |
Effect of vitamin B12 on performance and tissue selenium content in rats fed sub-toxic levels of selenite.
Topics: Animals; Diet; Intestinal Absorption; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; Selenium; Sodium Selenite; Tissue Distribution; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intravenous; Male; Methylation; Methylprednisolone Hemisuccinate; Middle Aged; Multiple Sclerosis; Myelin Sheath; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Isolation of two novel corrinoid proteins from acetate-grown Methanosarcina barkeri.
Topics: Acetates; Bacterial Proteins; Corrinoids; Electrophoresis, Polyacrylamide Gel; Iron; Methanosarcina barkeri; Methylation; Photolysis; Spectrophotometry; Vitamin B 12 | 1993 |
Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group.
Topics: Bacterial Proteins; Base Sequence; DNA, Single-Stranded; Methylation; Methyltransferases; Molecular Sequence Data; Oxidation-Reduction; Oxygenases; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1993 |
Cobalamin-mediated mercury methylation by Desulfovibrio desulfuricans LS.
Topics: Corrinoids; Culture Media; Desulfovibrio; Mercuric Chloride; Mercury; Methylation; Methylmercury Compounds; Vitamin B 12 | 1993 |
A novel antiviral strategy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; DNA, Viral; HIV; HIV Infections; HIV Seropositivity; Humans; Methylation; Proviruses; S-Adenosylmethionine; Tetrahydrofolates; Virus Replication; Vitamin B 12 | 1993 |
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12 | 1993 |
Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium.
Topics: Amino Acid Sequence; Base Sequence; Biological Evolution; Chromosome Mapping; Cobamides; Conserved Sequence; Gene Expression Regulation, Bacterial; Genes, Bacterial; Methylation; Methyltransferases; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Protein Biosynthesis; Salmonella typhimurium; Sequence Homology, Amino Acid; Vitamin B 12 | 1993 |
[Participation of methylcobalamin in DNA methylation in vitro].
Topics: Animals; Cattle; DNA; DNA Modification Methylases; DNA, Bacterial; Liver; Methylation; Micrococcus luteus; Rats; S-Adenosylmethionine; Vitamin B 12 | 1995 |
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate.
Topics: Case-Control Studies; Diet; Diet Surveys; Fasting; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methionine; Methylation; Middle Aged; Myocardial Infarction; Odds Ratio; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Mono- and dimethylation of arsenic in rat liver cytosol in vitro.
Topics: Animals; Arsenates; Arsenic; Arsenicals; Arsenites; Cacodylic Acid; Edetic Acid; Egtazic Acid; Glutathione; Liver; Male; Mercuric Chloride; Methylation; Methyltransferases; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Selenite; Vitamin B 12 | 1996 |
The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Protein Conformation; S-Adenosylmethionine; Sequence Homology, Amino Acid; Vitamin B 12 | 1996 |
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12 | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Homocysteine accumulation in human ovarian carcinoma ascitic/cystic fluids possibly caused by metabolic alteration of the methionine cycle in ovarian carcinoma cells.
Topics: Adult; Aged; Ascitic Fluid; Cysteine; Female; Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Middle Aged; Ovarian Neoplasms; Vitamin B 12 | 1997 |
Folate depletion induced by methotrexate affects methionine synthase activity and its susceptibility to inactivation by nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anesthetics, Inhalation; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methotrexate; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1997 |
How corrinoids are synthesized without oxygen: nature's first pathway to vitamin B12.
Topics: Anaerobiosis; Cobalt; Corrinoids; Methylation; Methyltransferases; Molecular Conformation; Oxygen; Porphyrins; Pseudomonas; Subcellular Fractions; Uroporphyrins; Vitamin B 12 | 1997 |
In vitro methylation of inorganic arsenic in mouse intestinal cecum.
Topics: Animals; Arsenic Poisoning; Arsenicals; Cecum; Chromatography, Thin Layer; Glutathione; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methionine; Methylation; Mice; Sodium Selenite; Sulfhydryl Compounds; Vitamin B 12 | 1997 |
Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Edetic Acid; Escherichia coli; Homocysteine; Methyl Methanesulfonate; Methylation; Mutagenesis; Protein Binding; Protons; Recombinant Proteins; Spectrophotometry; Spectrum Analysis; Tetrahydrofolates; Vitamin B 12; Zinc | 1997 |
Methionine synthase exists in two distinct conformations that differ in reactivity toward methyltetrahydrofolate, adenosylmethionine, and flavodoxin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkyl and Aryl Transferases; Binding, Competitive; Flavodoxin; Glycine; Histidine; Hydrolysis; Methylation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1998 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
The mechanism of adenosylmethionine-dependent activation of methionine synthase: a rapid kinetic analysis of intermediates in reductive methylation of Cob(II)alamin enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Aspartic Acid; Cobalt; Electron Transport; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1998 |
Transmethylation reactions and autoradiographic distribution of vitamin B12: effects of clioquinol treatment in mice.
Topics: Animals; Anti-Infective Agents, Local; Autoradiography; Brain; Chloroform; Clioquinol; Cobalt Radioisotopes; Kidney; Liver; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Scintillation Counting; Solubility; Tissue Distribution; Vitamin B 12; Water | 1998 |
Arsenite methylation by methylvitamin B12 and glutathione does not require an enzyme.
Topics: Arsenicals; Arsenites; Cacodylic Acid; Cytosol; Drug Synergism; Enzymes; Glutathione; Humans; Liver; Methylation; Reducing Agents; Sodium Selenite; Teratogens; Unithiol; Vitamin B 12 | 1999 |
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Folic Acid; Fruit; Homocysteine; Humans; Logistic Models; Male; Methylation; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Pyridoxine; Risk; Smoking; Vegetables; Vitamin B 12 | 1999 |
The role of an iron-sulfur cluster in an enzymatic methylation reaction. Methylation of CO dehydrogenase/acetyl-CoA synthase by the methylated corrinoid iron-sulfur protein.
Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Aldehyde Oxidoreductases; Bacterial Proteins; Catalysis; Iron-Sulfur Proteins; Kinetics; Methylation; Multienzyme Complexes; Oxidation-Reduction; Vitamin B 12 | 1999 |
The effect of diet on plasma homocysteine concentrations in healthy male subjects.
Topics: Adult; Cross-Sectional Studies; Diet; Diet, Vegetarian; Fasting; Folic Acid; Homocysteine; Humans; Male; Meat; Methionine; Methylation; Middle Aged; Vitamin B 12 | 1999 |
Moderately low vitamin B12 does not compromise transmethylation in adults on a free diet: implications for assessment of vitamin B12 status.
Topics: Analysis of Variance; Creatine; Dietary Proteins; Homocysteine; Humans; Methionine; Methylation; Reference Values; Statistics as Topic; Vitamin B 12 | 2000 |
The MtsA subunit of the methylthiol:coenzyme M methyltransferase of Methanosarcina barkeri catalyses both half-reactions of corrinoid-dependent dimethylsulfide: coenzyme M methyl transfer.
Topics: Archaeal Proteins; Base Sequence; Catalysis; DNA Primers; Kinetics; Methanosarcina barkeri; Methylation; Methyltransferases; Sulfides; Vitamin B 12 | 2001 |
Quantitation of rate enhancements attained by the binding of cobalamin to methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Activation; Escherichia coli; Genetic Vectors; Homocysteine; Kinetics; Methylation; Mutagenesis, Insertional; Peptide Fragments; Recombinant Proteins; Substrate Specificity; Vitamin B 12 | 2001 |
Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica.
Topics: Amino Acid Sequence; Anaerobiosis; Bacterial Proteins; Clostridium; Dicamba; Gram-Positive Rods; Hydroxocobalamin; Kinetics; Methylation; Methyltransferases; Molecular Sequence Data; Oxidoreductases, O-Demethylating; Tetrahydrofolates; Vanillic Acid; Vitamin B 12 | 2001 |
Formation and emission of volatile polonium compound by microbial activity and polonium methylation with methylcobalamin.
Topics: Air Pollutants; Environmental Monitoring; Geologic Sediments; Methylation; Polonium; Vitamin B 12; Volatilization; Water Microbiology | 2001 |
An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy.
Topics: Adult; Alleles; England; Erythrocytes; Female; Folic Acid; Gene Frequency; Humans; Methionine; Methylation; Mutation; Polyglutamic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Pregnancy; Pteroylpolyglutamic Acids; Spinal Dysraphism; Vitamin B 12 | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
Functional modeling of cobalamine-independent methionine synthase with pyrazolylborate-zinc-thiolate complexes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkylation; Borates; Catalysis; Crystallography, X-Ray; Kinetics; Methylation; Models, Chemical; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Pyrazoles; Spectrophotometry, Infrared; Sulfhydryl Compounds; Sulfuric Acid Esters; Vitamin B 12; Zinc | 2001 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
Methyl transfer from rhenium to coordinated thiolate groups.
Topics: Methylation; Molecular Mimicry; Molecular Structure; Rhenium; Sulfides; Vitamin B 12 | 2002 |
Medical hypothesis: hyperhomocysteinemia is a risk factor for estrogen-induced hormonal cancer.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Estradiol; Estrogens; Estrogens, Catechol; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kinetics; Methylation; Models, Biological; Mutagenicity Tests; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Risk Factors; S-Adenosylhomocysteine; Uterine Neoplasms; Vitamin B 12; Vitamin B 6 | 2003 |
Nutritional modulation of gene expression and homocysteine utilization by vitamin B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Animals; Carcinoma, Hepatocellular; COS Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Kidney; Liver Neoplasms; Methylation; Nucleic Acid Conformation; Nutritional Physiological Phenomena; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured; Vitamin B 12 | 2003 |
Changes in GE2270 antibiotic production in Planobispora rosea through modulation of methylation metabolism.
Topics: Actinomycetales; Adenosine; Anti-Bacterial Agents; Culture Media; Drug Interactions; Fermentation; Methionine; Methylation; Molecular Structure; Peptides; Peptides, Cyclic; Thiazoles; Vitamin B 12 | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
The relation of vitamin B12 to the methylation of homocystine in poults.
Topics: Animals; Corrinoids; Cystine; Formularies as Topic; Homocystine; Methylation; Turkeys; Vitamin B 12; Vitamin B 12 Deficiency | 1953 |
Rôle of folic acid and vitamin B12 in transmethylations. III. An influence of folic acid on the methylation of nicotinamide.
Topics: Folic Acid; Humans; Methylation; Niacin; Niacinamide; Nicotinic Acids; Vitamin B 12; Vitamin B Complex | 1955 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
Methylation of nicotinamide in vitamin B12- and vitamin B6-deficient rats.
Topics: Animals; Methylation; Niacin; Niacinamide; Nicotinic Acids; Rats; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 1962 |
Methylation of homocystine by chicks deficient in vitamin B12.
Topics: Animals; Chickens; Corrinoids; Cystine; Hematinics; Homocystine; Methylation; Vitamin B 12 | 1951 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Methyl transfer reactivity of five-coordinate CH3CoIIIPc.
Topics: Indoles; Kinetics; Methylation; Models, Chemical; Molecular Structure; Organometallic Compounds; Vitamin B 12 | 2005 |
Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin.
Topics: Amides; Bacterial Proteins; Cell Proliferation; Cobamides; Escherichia coli; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Engineering; Methylation; Models, Chemical; Models, Molecular; Plasmids; Porphyrinogens; Propionibacterium; Salmonella typhimurium; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Abiotic methylation of mercury in the aquatic environment.
Topics: Bacteria; Chlorides; Hydrocarbons, Iodinated; Hydrogen-Ion Concentration; Mercury; Methylation; Methylmercury Compounds; Organotin Compounds; Temperature; Vitamin B 12; Water Pollutants, Chemical | 2006 |
Synthesis of substrate analogs of methyltransferases in the vitamin B(12) biosynthetic pathway and characterization of their enzymatic products.
Topics: Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Structure; Porphyrinogens; Porphyrins; Reference Standards; Sensitivity and Specificity; Stereoisomerism; Substrate Specificity; Vitamin B 12 | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Iron and the folate-vitamin B12-methylation pathway in multiple sclerosis.
Topics: Adult; Anti-Inflammatory Agents; Black People; Dietary Fats; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Interferons; Iron; Magnetic Resonance Imaging; Male; Methylation; Multiple Sclerosis; Nutritional Status; Patient Compliance; Pilot Projects; Prednisone; Vitamin B 12; White People | 2006 |
Enhancing the methyl-donor activity of methylcobalamin by covalent attachment of DNA.
Topics: DNA; Methylation; Molecular Structure; Vitamin B 12 | 2005 |
Folate and methylation status in relation to phosphorylated tau protein(181P) and beta-amyloid(1-42) in cerebrospinal fluid.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amyloid beta-Peptides; Biomarkers; Cysteine; Female; Folic Acid; Humans; Male; Methylation; Middle Aged; Nervous System Diseases; Neurodegenerative Diseases; Peptide Fragments; Phosphorylation; S-Adenosylhomocysteine; tau Proteins; Vitamin B 12 | 2007 |
Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects.
Topics: Aged; Biomarkers; Caffeine; Cross-Over Studies; Drinking; Eating; Fasting; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Phenols; Polyphenols; Tea; Vitamin B 12 | 2007 |
Consumption of folate-related nutrients and metabolism of arsenic in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Choline; Cysteine; Dietary Proteins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Niacin; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
Synergy between paclitaxel plus an exogenous methyl donor in the suppression of murine demyelinating diseases.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autoimmune Diseases; Demyelinating Diseases; Drug Synergism; Gliosis; Methylation; Mice; Mice, Inbred Strains; Mice, Transgenic; Myelin Basic Protein; Nerve Fibers, Myelinated; Nerve Regeneration; Paclitaxel; STAT1 Transcription Factor; T-Lymphocytes; Vitamin B 12; Vitamin B Complex | 2007 |
Probing the role of the histidine 759 ligand in cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Chromatography, Liquid; Circular Dichroism; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Histamine; Ligands; Methylation; Molecular Probes; Vitamin B 12 | 2007 |
Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.
Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Ligands; Methanobacteriaceae; Methylation; Methyltransferases; Protein Conformation; Substrate Specificity; Vitamin B 12 | 2007 |
Methyl transfer from methylcobaloxime to (triphos)Ni(PPh(3)): relevance to the mechanism of acetyl coenzyme A synthase.
Topics: Acetate-CoA Ligase; Binding Sites; Catalysis; Magnetic Resonance Spectroscopy; Methylation; Nickel; Organometallic Compounds; Phosphates; Time Factors; Vitamin B 12 | 2007 |
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Enzyme Activation; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Temperature; Thermotoga maritima; Vitamin B 12 | 2007 |
Metabolic pathways leading from amino acids to vitamin B12 in Propionibacterium shermanii, and the sources of the seven methyl carbons.
Topics: Amino Acids; Carbon; Magnetic Resonance Spectroscopy; Methylation; Propionibacterium; Vitamin B 12 | 2007 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Crystallography, X-Ray; Elasticity; Homocysteine; Metals; Methylation; Methyltransferases; Protein Conformation; Thermotoga maritima; Vitamin B 12; Zinc | 2008 |
Cobalt limitation of growth and mercury methylation in sulfate-reducing bacteria.
Topics: Cobalt; Mercury; Methylation; Methylmercury Compounds; Sulfates; Sulfides; Sulfur-Reducing Bacteria; Vitamin B 12 | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.
Topics: Autistic Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Glutathione; Humans; Leucovorin; Male; Methylation; Nutritional Status; Oxidation-Reduction; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Vitamin B(12) model complex catalyzed methyl transfer reaction to alkylthiol under electrochemical conditions with sacrificial electrode.
Topics: Benzenesulfonates; Catalysis; Cobalt; Electrodes; Methylation; Oxidation-Reduction; Sulfhydryl Compounds; Vitamin B 12; Zinc | 2009 |
Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model.
Topics: Action Potentials; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Ganglia, Spinal; In Situ Nick-End Labeling; Methylation; Motor Activity; Muscle, Skeletal; Nerve Regeneration; Neurites; Neurons; Oncogene Protein v-akt; Rats; Rats, Wistar; Recovery of Function; Sciatic Neuropathy; Sensation; Tubulin; Vitamin B 12 | 2010 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2011 |
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12 | 2011 |
Congenital heart defects and biomarkers of methylation in children: a case-control study.
Topics: Biomarkers; Case-Control Studies; Child, Preschool; Down Syndrome; Female; Folic Acid; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Male; Methylation; Netherlands; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Vitamin B 12 | 2011 |
A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia.
Topics: Adult; Biomarkers; Carbon; Case-Control Studies; Cervix Uteri; Confidence Intervals; Deoxyribonuclease I; DNA Methylation; Epigenomics; Female; Folic Acid; Follow-Up Studies; Humans; Leukocytes, Mononuclear; Logistic Models; Methylation; Middle Aged; Odds Ratio; Papillomavirus Infections; Premenopause; Promoter Regions, Genetic; Prospective Studies; Risk Factors; Surveys and Questionnaires; Uterine Cervical Dysplasia; Vitamin B 12; Vitamin B Complex; Young Adult | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Connection between multimetal(loid) methylation in methanoarchaea and central intermediates of methanogenesis.
Topics: ATP-Binding Cassette Transporters; Bacterial Proteins; Mesna; Metals; Methanosarcina; Methylation; Methyltransferases; Recombinant Proteins; Vitamin B 12 | 2011 |
Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Topics: Binding Sites; Biocatalysis; Corrinoids; Crystallography, X-Ray; Folic Acid; Iron-Sulfur Proteins; Methylation; Methyltransferases; Models, Biological; Models, Molecular; Moorella; Protein Multimerization; Protein Structure, Tertiary; Vitamin B 12 | 2012 |
Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver.
Topics: Animals; Electron Transport; Endoplasmic Reticulum Stress; Energy Metabolism; ERRalpha Estrogen-Related Receptor; Estrogen Receptor alpha; Fatty Acids; Fatty Liver; Folic Acid; Hepatocyte Nuclear Factor 4; Liver; Methylation; Oxidation-Reduction; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; Receptors, Estrogen; RNA-Binding Proteins; Transcription Factors; Vitamin B 12 | 2012 |
Position-specific isotope analysis of the methyl group carbon in methylcobalamin for the investigation of biomethylation processes.
Topics: Arsenicals; Carbon; Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Glutathione; Methylation; Vitamin B 12 | 2013 |
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex | 2013 |
Whole body methionine kinetics, transmethylation, transulfuration and remethylation during pregnancy.
Topics: Adult; Anthropometry; Carbon Isotopes; Cohort Studies; Dietary Proteins; Feeding Behavior; Female; Humans; India; Methionine; Methylation; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2014 |
The mechanisms of radical SAM/cobalamin methylations: an evolving working hypothesis.
Topics: Anti-Bacterial Agents; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiostrepton; Tryptophan; Vitamin B 12 | 2013 |
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
Topics: Biocatalysis; Free Radicals; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2013 |
Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis.
Topics: Dithionite; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; Protein Refolding; Streptomyces; Vitamin B 12 | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12 | 2014 |
Methyl donor deficiency in H9c2 cardiomyoblasts induces ER stress as an important part of the proteome response.
Topics: Animals; Biomarkers; Blotting, Western; Cell Line; Cell Size; Cell Survival; Densitometry; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Stress; Folic Acid; Gene Ontology; Gene Regulatory Networks; Intracellular Space; Methylation; Myocytes, Cardiac; Proteasome Endopeptidase Complex; Proteome; Proteomics; Rats; RNA, Messenger; Time Factors; Ubiquitin; Vitamin B 12 | 2015 |
Clinical onset and course, response to treatment and outcome in 24 patients with the cblE or cblG remethylation defect complemented by genetic and in vitro enzyme study data.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Age of Onset; Amino Acid Metabolism, Inborn Errors; Cells, Cultured; Child; Child, Preschool; Disease Progression; Female; Ferredoxin-NADP Reductase; Humans; Infant; Infant, Newborn; Male; Methylation; Pregnancy; Retrospective Studies; Treatment Outcome; Vitamin B 12; Young Adult | 2015 |
Cobalamin-dependent enzymatic O-, N-, and S-demethylation.
Topics: Biotechnology; Methylation; Methyltransferases; Vitamin B 12 | 2015 |
Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Catalysis; Cephalosporins; Chromatography, Liquid; Cloning, Molecular; DNA Methylation; Drug Design; Escherichia coli; Fermentation; Methylation; Penicillins; S-Adenosylmethionine; Streptomyces; Tandem Mass Spectrometry; Thienamycins; Vitamin B 12 | 2015 |
Emerging Diversity of the Cobalamin-Dependent Methyltransferases Involving Radical-Based Mechanisms.
Topics: Anti-Bacterial Agents; Methylation; Methyltransferases; Models, Chemical; Thienamycins; Thiostrepton; Vitamin B 12 | 2016 |
Neuregulin 1 Promotes Glutathione-Dependent Neuronal Cobalamin Metabolism by Stimulating Cysteine Uptake.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Androstadienes; Cell Line, Tumor; Cysteine; Excitatory Amino Acid Transporter 3; Glutathione; Humans; Low Density Lipoprotein Receptor-Related Protein-2; Methylation; Neuregulin-1; Neurons; Real-Time Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Vitamin B 12; Wortmannin | 2016 |
The B
Topics: Biocatalysis; Free Radicals; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Molecular Conformation; Proteins; S-Adenosylmethionine; Vitamin B 12 | 2016 |
Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis.
Topics: Biosynthetic Pathways; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Streptomyces; Substrate Specificity; Vitamin B 12 | 2017 |
Influence of phenylketonuria's diet on dimethylated arginines and methylation cycle.
Topics: Arginine; Biomarkers; Child; Chromatography, High Pressure Liquid; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Mass Spectrometry; Methylation; Patient Compliance; Phenylketonurias; Severity of Illness Index; Vitamin B 12 | 2017 |
Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical
Topics: Bacterial Proteins; Biocatalysis; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Kinetics; Methylation; Methyltransferases; Molecular Structure; Recombinant Fusion Proteins; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry; Staphylococcus; Substrate Specificity; Thiostrepton; Tryptophan; Vitamin B 12 | 2017 |
TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.
Topics: Bacterial Proteins; Biocatalysis; Coenzymes; Cysteine; Escherichia coli; Iron-Sulfur Proteins; Methylation; Methyltransferases; Protein Binding; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; Tryptophan; Vitamin B 12 | 2017 |
Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.
Topics: Biosynthetic Pathways; Catalytic Domain; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2017 |
C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-adenosyl-l-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Liquid; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Stereospecific Radical-Mediated B
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Free Radicals; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Topics: Animals; Biological Transport; Brain; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cell Nucleus; ELAV-Like Protein 1; Endoplasmic Reticulum Stress; Exportin 1 Protein; Humans; Karyopherins; Metabolic Diseases; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; Receptors, Cytoplasmic and Nuclear; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Sirtuin 1; Vitamin B 12 | 2018 |
Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase.
Topics: Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.
Topics: Adult; Arsenic; Biomarkers; Cohort Studies; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylation; Mexico; Pregnancy; Pregnant Women; Regression Analysis; Vitamin B 12; Young Adult | 2018 |
Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B
Topics: Anisoles; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Enzyme Assays; Esters; Free Radicals; Methylation; Methyltransferases; Myxococcales; Nitro Compounds; Recombinant Proteins; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: Data from the E-HOD registry.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cross-Sectional Studies; Disease Progression; Europe; Female; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Muscle Spasticity; Phenotype; Pregnancy; Psychotic Disorders; Registries; Retrospective Studies; Vitamin B 12; Young Adult | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
Methanogenesis marker protein 10 (Mmp10) from
Topics: Archaeal Proteins; Biocatalysis; Chromatography, High Pressure Liquid; Kinetics; Matrix Metalloproteinase 10; Methanosarcina; Methylation; Peptides; Recombinant Proteins; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Vitamin B 12 | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
Understanding the role of electron donors in the reaction catalyzed by Tsrm, a cobalamin-dependent radical S-adenosylmethionine methylase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Dithiothreitol; Escherichia coli; Hydroxocobalamin; Iron-Sulfur Proteins; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2019 |
Surprise! A hidden B
Topics: Biocatalysis; Matrix Metalloproteinase 10; Methylation; Oxidoreductases; Peptides; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2019 |
A diet rich in taurine, cysteine, folate, B
Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; Humans; Hydrogen Sulfide; Methylation; Risk; Taurine; Vitamin B 12 | 2019 |
Association of plasma folate, vitamin B12 levels, and arsenic methylation capacity with developmental delay in preschool children in Taiwan.
Topics: Arsenates; Arsenicals; Arsenites; Cacodylic Acid; Case-Control Studies; Child, Preschool; Developmental Disabilities; Female; Folic Acid; Humans; Male; Methylation; Odds Ratio; Taiwan; Vitamin B 12 | 2019 |
Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus.
Topics: Animals; Appetite Depressants; Energy Metabolism; Feeding Behavior; Female; Folic Acid; Gene Expression Regulation; Ghrelin; Hypothalamus; Insulin; Lactation; Leptin; Methylation; Peptide YY; Pregnancy; Pro-Opiomelanocortin; Rats; RNA, Messenger; Vitamin B 12 | 2019 |
Methylations in complex carbapenem biosynthesis are catalyzed by a single cobalamin-dependent radical S-adenosylmethionine enzyme.
Topics: Anti-Bacterial Agents; Carbapenems; Catalysis; Methionine Adenosyltransferase; Methylation; Vitamin B 12 | 2019 |
Vitamin B-6 Intake Is Modestly Associated with Arsenic Methylation in Uruguayan Children with Low-Level Arsenic Exposure.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Child; Cross-Sectional Studies; Diet; Energy Intake; Environmental Exposure; Female; Humans; Inactivation, Metabolic; Male; Methylation; Niacin; Riboflavin; Thiamine; Uruguay; Vitamin B 12; Vitamin B 6; Water | 2020 |
Anaerobic bacteria need their vitamin B
Topics: Androgens; Bacteria; Bacteria, Anaerobic; Estrogens; Methylation; Vitamin B 12; Vitamins | 2020 |
Identification and characterization of a bacterial core methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Chloroflexi; Dehalococcoides; Escherichia coli; Genome, Bacterial; Homocysteine; Methionine; Methylation; Phylogeny; Vitamin B 12 | 2020 |
Associations of dietary intakes and serum levels of folate and vitamin B-12 with methylation of inorganic arsenic in Uruguayan children: Comparison of findings and implications for future research.
Topics: Arsenic; Arsenicals; Child; Eating; Environmental Exposure; Folic Acid; Humans; Methylation; Research; Uruguay; Vitamin B 12; Vitamins | 2020 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Topics: Arginine; Catalysis; Coenzymes; Iron-Sulfur Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomycetaceae; Thiostrepton; Tryptophan; Vitamin B 12; X-Ray Diffraction | 2021 |
Methyl transfer reactions catalyzed by cobalamin-dependent enzymes: Insight from molecular docking.
Topics: Catalysis; Methylation; Methyltransferases; Molecular Docking Simulation; Vitamin B 12 | 2021 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
Overall Retention of Methyl Stereochemistry during B
Topics: Bacterial Proteins; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2021 |
Crystallographic snapshots of a B
Topics: Archaeal Proteins; Electron Spin Resonance Spectroscopy; Methanosarcina; Methylation; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Structure of a B
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Biocatalysis; Carbapenems; Coenzymes; Crystallography, X-Ray; Kinetics; Methylation; Methyltransferases; Models, Molecular; Protein Binding; Protein Domains; S-Adenosylmethionine; Streptomyces; Thienamycins; Vitamin B 12 | 2022 |
Exploring the Biosynthetic Potential of TsrM, a B
Topics: Methylation; Methyltransferases; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2022 |
The Atypical Cobalamin-Dependent
Topics: Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
A Cobalamin-Dependent Radical SAM Enzyme Catalyzes the Unique C
Topics: Glutamine; Methane; Methylation; Methyltransferases; Oxidoreductases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Topics: Adult; Arsenic; Arsenicals; Biomarkers; Birth Weight; Carbon; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2022 |
Mechanism of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine; Vitamin B 12 | 2022 |