Page last updated: 2024-08-18

isomethyleugenol and troleandomycin

isomethyleugenol has been researched along with troleandomycin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Juvonen, RO; Kojo, A; Komulainen, H; Liesivuori, J; Pasanen, M; Pennanen, S1
Huang, SL; Wang, JS; Wang, W; Xie, HG; Zhou, HH1
Shimada, T; Yamazaki, H2
Huang, SL; Ou-Yang, DS; Wu, ZL; Xie, HG; Xu, ZH; Zhou, HH1
Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P1
Di Marco, A; Laufer, R; Yao, D1

Trials

1 trial(s) available for isomethyleugenol and troleandomycin

ArticleYear
Effect of troleandomycin on the pharmacokinetics of imipramine in Chinese: the role of CYP3A.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; China; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Imipramine; Male; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating; Reference Values; Troleandomycin

1997

Other Studies

6 other study(ies) available for isomethyleugenol and troleandomycin

ArticleYear
CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: Aged; Animals; Antibodies, Monoclonal; Caproates; Cytochrome P-450 Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Male; Methylation; Metyrapone; Mice; Microsomes, Liver; Middle Aged; NADPH-Ferrihemoprotein Reductase; Occupational Exposure; Proadifen; Quinidine; Rats; Rats, Wistar; Troleandomycin

1996
Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:11

    Topics: Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythromycin; Humans; Hydroxylation; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Recombinant Proteins; Roxithromycin; Steroid Hydroxylases; Troleandomycin

1998
Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Iron; Male; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Roxithromycin; Testosterone; Troleandomycin

1998
Clomipramine N-demethylation metabolism in human liver microsomes.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Adult; Clomipramine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; In Vitro Techniques; Mephenytoin; Methylation; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Troleandomycin

1998
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured

2000
Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
    European journal of biochemistry, 2003, Volume: 270, Issue:18

    Topics: Animals; Benzoflavones; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Hepatocytes; Inhibitory Concentration 50; Kinetics; Male; Methylation; Microsomes, Liver; Oxidoreductases, O-Demethylating; Protein Binding; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Troleandomycin

2003