Page last updated: 2024-08-18

isomethyleugenol and theophylline

isomethyleugenol has been researched along with theophylline in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199025 (64.10)18.7374
1990's8 (20.51)18.2507
2000's3 (7.69)29.6817
2010's3 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boutroy, MJ; Monin, P; Royer, RJ; Royer-Morrot, MJ; Vert, P1
Aldridge, A; Aranda, JV; Haber, R; Louridas, AT; Thom, P; Vitullo, BB1
Ido, T; Iwata, R; Kasida, Y; Saji, H; Suzuki, K; Tamate, K; Yoshikawa, K1
Kihlman, BA; Sturelid, S1
Bailey, DG; Davis, HL; Johnson, GE1
Dusci, LJ; Hackett, LP; McDonald, IA1
Battula, N; Doehmer, J; Fuhr, U; Keita, Y; Kudla, C; Staib, AH; Wölfel, C1
Benyon, RC; Church, MK; Hughes, PJ1
Carvounis, CP; Carvounis, G; Wilk, BJ1
Fisher, D; Giese, RW; Joppich, M; Nazareth, A; Panthani, A1
Baxter, JH; Beaven, MA; Horáková, Z1
Buneaux, JJ; Gounelle, JC; Raoul, Y1
Jenne, JW; Nagasawa, HT; Thompson, RD1
Fujii, T; Nishimura, H1
Cornish, HH; Khanna, KL; Rao, GS1
Campiglio, A1
de Bree, PK; Haverkamp, J; van der Heiden, C; van Gennip, AH; Vliegenthart, JF; Wadman, SK1
Lafitte, P; Macquet, V; Rogeaux, Y1
Kalsner, S1
Gräfe, G; Haller, R; Kleine, KH1
Staub, MS; Symchowicz, S; Tabachnick, II; Wong, KK1
Robinette, CD1
Axelrod, JA; Hirata, F; Ishizaka, K; Ishizaka, T; Sterk, AR1
Pike, MC; Snyderman, R1
Haley, TJ1
Brazier, JL; Desage, M; Renaud, H; Ribon, B; Salle, B1
Kaminsky, LS; Zhang, ZY1
Jang, IJ; Kim, SW; Lee, KH; Lee, SH; Lee, SW; Oh, SJ; Shin, SG; Yim, DS1
Camborde, F; Caussade, F; Cloarec, A; Güngör, T; Hertz, F; Malabre, P; Meignen, J; Teulon, JM; Virone-Oddos, A1
Brøsen, K; Rasmussen, BB1
Jones, BC; Smith, DA; Tyman, CA1
Huang, SL; Ou-Yang, DS; Wu, ZL; Xie, HG; Xu, ZH; Zhou, HH1
Iakovlev, SV; Iakovlev, VP1
Choo, EF; Mayo, G; Shyr, Y; Sofowora, GG; Wilkinson, GR1
Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y1
Pawlukojc, A; Prager, M; Wischnewski, A; Wuttke, J1
Fujino, H; Hosaka, S; Iwasaki, K; Murayama, N; Onose, Y; Shimizu, M; Uno, Y; Utoh, M; Yamazaki, H1
da Silva, JF; Gonçalves, JF; Kiyota, E; Mayer, JL; Mazzafera, P; Schimpl, FC1
Aravind, UK; Aravindakumar, CT; Pramod, G; Saha, A; Sunil Paul, MM1

Reviews

2 review(s) available for isomethyleugenol and theophylline

ArticleYear
Metabolism and pharmacokinetics of theophylline in human neonates, children, and adults.
    Drug metabolism reviews, 1983, Volume: 14, Issue:2

    Topics: Adult; Age Factors; Apnea; Asthma; Biotransformation; Bradycardia; Caffeine; Child; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kinetics; Male; Methylation; Pulmonary Edema; Theophylline; Tissue Distribution

1983
[Pharmacokinetic interactions between fluoroquinolones and methylxanthines].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1999, Volume: 44, Issue:3

    Topics: Anti-Infective Agents; Caffeine; Drug Interactions; Fluoroquinolones; Humans; Methylation; Theophylline; Xanthines

1999

Other Studies

37 other study(ies) available for isomethyleugenol and theophylline

ArticleYear
Methylation of theophylline to caffeine in premature infants.
    Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120

    Topics: Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Methylation; Theophylline; Xanthines

1979
Metabolism of theophylline to caffeine in human fetal liver.
    Science (New York, N.Y.), 1979, Dec-14, Volume: 206, Issue:4424

    Topics: Apnea; Biotransformation; Caffeine; Cells, Cultured; Gestational Age; Humans; Infant, Newborn; Liver; Methylation; Theophylline

1979
[Caffeine-11C, ephedrine-11C and methylephedrine-11C: Synthesis and distribution in mice (author's transl)].
    Radioisotopes, 1978, Volume: 27, Issue:8

    Topics: Animals; Caffeine; Carbon Radioisotopes; Ephedrine; Isotope Labeling; Male; Methylation; Mice; Phenylpropanolamine; Theophylline; Time Factors; Tissue Distribution

1978
Enhancement by methylated oxypurines of the frequency of induced chromosomal aberrations.
    Hereditas, 1975, Volume: 79, Issue:1

    Topics: Animals; Caffeine; Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cricetinae; Drug Synergism; Methylation; Mutation; Plants; Purines; Theobromine; Theophylline; Thiotepa; Uric Acid

1975
Improved theophylline serum analysis by an appropriate internal standard for gas chromatography.
    Journal of chromatography, 1976, Jun-23, Volume: 121, Issue:2

    Topics: Chromatography, Gas; Humans; Methylation; Solvents; Theophylline; Xanthines

1976
Gas-liquid chromatographic determination of theophylline in human plasma.
    Journal of chromatography, 1975, Jan-29, Volume: 104, Issue:1

    Topics: Caffeine; Chromatography, Gas; Hot Temperature; Humans; Methods; Methylation; Microchemistry; Theophylline

1975
Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Biotransformation; Caffeine; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Genetic Engineering; Humans; Hydroxylation; Methylation; Mice; Rats; Species Specificity; Theophylline; Xanthines

1992
Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Methylation; Phospholipids; S-Adenosylmethionine; Theophylline; Tubercidin

1987
Importance of amino acids on vasopressin-stimulated water flow.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:2

    Topics: Amino Acids; Animals; Bufonidae; Cyclic AMP; Diuresis; Drug Synergism; Female; Glutamates; Glutamic Acid; Histidine; Lysine; Methylation; Structure-Activity Relationship; Theophylline; Urinary Bladder; Vasopressins; Zinc

1985
Alkylation with dialkylsulfate and diisopropylethylamine.
    Journal of chromatography, 1985, Feb-20, Volume: 319, Issue:3

    Topics: Alkylation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Ethylamines; Methylation; Sulfuric Acid Esters; Sulfuric Acids; Theophylline

1985
Effects of adrenergic agents, theophylline and other drugs on dextran edema and histamine release in rats.
    Biochemical pharmacology, 1974, Apr-01, Volume: 23, Issue:7

    Topics: Animals; Blood Glucose; Bucladesine; Carbon Radioisotopes; Dextrans; Edema; Epinephrine; Female; Histamine; Histamine Release; Hyperglycemia; Isoproterenol; Methylation; Methyltransferases; Norepinephrine; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Rats; S-Adenosylmethionine; Skin; Sympathomimetics; Theophylline; Time Factors

1974
[Messenger role of 3'5' adenosine monophosphoric acid (cyclic AMP) in the action of somatotropic hormone on the uptake of 14C glucose by the diaphragm of hypophysectomized rats].
    Journal de physiologie, 1972, Volume: 65

    Topics: Adenylyl Cyclases; Animals; Carbon Isotopes; Cyclic AMP; Diaphragm; Glucose; Growth Hormone; Hypophysectomy; Imidazoles; Methylation; Phosphoric Diester Hydrolases; Rats; Theophylline

1972
Determination of theophylline and its metabolites in human urine and serum by high-pressure liquid chromatography.
    The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:4

    Topics: Administration, Oral; Aminophylline; Caffeine; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Ion Exchange; Humans; Hypoxanthines; Methylation; Pressure; Theophylline; Uric Acid; Xanthines

1974
Fetal hypoproteinemia associated with generalized edema caused by administration of methyl xanthines to the rat during late pregnancy.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:6

    Topics: Animals; Blood Proteins; Body Water; Body Weight; Caffeine; Edema; Female; Fetal Diseases; Fetus; Gestational Age; Hypoproteinemia; Methylation; Pregnancy; Rats; Theobromine; Theophylline; Xanthines

1973
Mass spectrometric identification of methylxanthines and methyluric acids, the possible metabolites of caffeine.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:11

    Topics: Caffeine; Chromatography, Gas; Mass Spectrometry; Methods; Methylation; Theobromine; Theophylline; Uric Acid; Xanthines

1972
[Determination of the N-methyl group in organic substances on the micro and decimomilligram scale].
    Il Farmaco; edizione scientifica, 1973, Volume: 28, Issue:1

    Topics: Acetanilides; Aminopyrine; Antipyrine; Caffeine; Diphenhydramine; Ephedrine; Indicators and Reagents; Methylation; Microchemistry; Theobromine; Theophylline

1973
Urinary excretion of 3 -methylxanthine and related compounds in children.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Apr-30, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Cacao; Caffeine; Child; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Paper; Coffee; Diet; Humans; Infant; Intellectual Disability; Mass Spectrometry; Methylation; Neuromuscular Diseases; Spectrophotometry, Ultraviolet; Stereoisomerism; Tea; Theobromine; Theophylline; Xanthines

1973
[Use of an S-carboxy-methyl-cysteine and theophylline combination in the treatment of chronic bronchitis].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1973, Volume: 18, Issue:9

    Topics: Bronchitis; Carboxylic Acids; Chronic Disease; Cysteine; Drug Combinations; Expectorants; Humans; Methylation; Theophylline

1973
Mechanism of potentiation of contractor responses to catecholamines by methylxanthines in aortic strips.
    British journal of pharmacology, 1971, Volume: 43, Issue:2

    Topics: Animals; Aorta; Caffeine; Catecholamines; Cycloparaffins; Drug Synergism; Epinephrine; In Vitro Techniques; Ketones; Methoxamine; Methylation; Muscle Contraction; Muscle, Smooth; Norepinephrine; Normetanephrine; Phenylephrine; Propiophenones; Pyrogallol; Rabbits; Reserpine; Synephrine; Theophylline; Xanthines

1971
[Synthesis of substituted bis-xanthines].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:11

    Topics: Amines; Chemistry, Pharmaceutical; Ethers, Cyclic; Methylation; Theobromine; Theophylline; Xanthines

1969
The in vitro effect of catecholamines, diazoxide and theophylline on insulin release.
    Life sciences, 1967, Nov-01, Volume: 6, Issue:21

    Topics: Animals; Catecholamines; Diazoxide; Immunoassay; In Vitro Techniques; Insulin; Insulin Secretion; Male; Methylation; Pancreas; Rabbits; Theophylline

1967
Methylated xanthines and pancreatic cancer.
    Lancet (London, England), 1981, Oct-03, Volume: 2, Issue:8249

    Topics: Bronchodilator Agents; Coffee; Humans; Male; Methylation; Pancreatic Neoplasms; Theophylline; Xanthines

1981
Bridging of IgE receptors activates phospholipid methylation and adenylate cyclase in mast cell plasma membranes.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:11

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Immunoglobulin E; Immunoglobulin Fab Fragments; Kinetics; Mast Cells; Methylation; Propranolol; Rats; Rats, Inbred Strains; Receptors, IgE; Receptors, Immunologic; Theophylline

1981
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
    Cell, 1982, Volume: 28, Issue:1

    Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline

1982
In vivo N7 methylation of theophylline to caffeine in premature infants. Studies with use of stable isotopes.
    Developmental pharmacology and therapeutics, 1981, Volume: 2, Issue:3

    Topics: Caffeine; Carbon Isotopes; Humans; Infant, Newborn; Infant, Premature; Methylation; Nitrogen Isotopes; Phenobarbital; Theophylline; Time Factors

1981
Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation.
    Biochemical pharmacology, 1995, Jul-17, Volume: 50, Issue:2

    Topics: Cell Line; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Isoenzymes; Kinetics; Methylation; Microsomes, Liver; Oxidoreductases; Theophylline; Transfection; Uric Acid

1995
CYP1A2 activity as a risk factor for bladder cancer.
    Journal of Korean medical science, 1994, Volume: 9, Issue:6

    Topics: Acetylation; Adult; Aged; Amines; Carcinoma, Transitional Cell; Case-Control Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Disease Susceptibility; Enzyme Induction; Female; Humans; Isoniazid; Korea; Logistic Models; Male; Methylation; Metoprolol; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Smoking; Theophylline; Uric Acid; Urinary Bladder Neoplasms

1994
N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents.
    Journal of medicinal chemistry, 1994, Dec-09, Volume: 37, Issue:25

    Topics: Adenosine; Analgesia; Analgesics; Animals; Indoles; Methylation; Mice; Molecular Structure; Nitrogen; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline

1994
Theophylline has no advantages over caffeine as a putative model drug for assessing CYPIA2 activity in humans.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:3

    Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Male; Metabolic Clearance Rate; Methylation; Microsomes, Liver; Phosphodiesterase Inhibitors; Theophylline

1997
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:10

    Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline

1997
Clomipramine N-demethylation metabolism in human liver microsomes.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Adult; Clomipramine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; In Vitro Techniques; Mephenytoin; Methylation; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Troleandomycin

1998
In vivo inhibition of human CYP1A2 activity by oltipraz.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6

    Topics: Adult; Antineoplastic Agents; Caffeine; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Female; Humans; Male; Methylation; Pyrazines; Theophylline; Thiones; Thiophenes

2001
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2

    Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines

2002
Inelastic neutron scattering study of methyl groups rotation in some methylxanthines.
    The Journal of chemical physics, 2007, Dec-07, Volume: 127, Issue:21

    Topics: Caffeine; Methylation; Models, Chemical; Models, Molecular; Neutron Diffraction; Rotation; Spectrum Analysis; Theobromine; Theophylline; Thermodynamics; Xanthines

2007
Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:12

    Topics: Animals; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Haplorhini; Humans; Hydroxylation; Liver; Metabolic Networks and Pathways; Methylation; Microsomes, Liver; Molecular Docking Simulation; Oxidation-Reduction; Recombinant Proteins; Theophylline

2013
Molecular and biochemical characterization of caffeine synthase and purine alkaloid concentration in guarana fruit.
    Phytochemistry, 2014, Volume: 105

    Topics: Alkaloids; Amino Acid Sequence; Base Sequence; Caffeine; Fruit; Methylation; Methyltransferases; Molecular Structure; Paullinia; Plant Leaves; Purines; Seeds; Theobromine; Theophylline; Xanthines

2014
Hydroxyl radical induced oxidation of theophylline in water: a kinetic and mechanistic study.
    Organic & biomolecular chemistry, 2014, Aug-14, Volume: 12, Issue:30

    Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Light; Mass Spectrometry; Methylation; Oxidation-Reduction; Pulse Radiolysis; Spectrum Analysis; Theophylline; Uric Acid; Water; Xanthine

2014