Page last updated: 2024-08-18

isomethyleugenol and tamoxifen

isomethyleugenol has been researched along with tamoxifen in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.79)18.7374
1990's6 (20.69)18.2507
2000's3 (10.34)29.6817
2010's9 (31.03)24.3611
2020's7 (24.14)2.80

Authors

AuthorsStudies
Beaune, P; Berthou, F; Dreano, Y; Jacolot, F; Riche, C; Simon, I1
Davidson, NE; Gelmann, EP; Kasid, A; Lippman, ME1
Chambon, P; Kumar, V1
Glenn, EM; Ludens, JH; Rohloff, NA; Skulnick, HI; Smith, RJ; Wendling, MG; Wierenga, W1
Eppenberger, U; Löser, R; Seibel, K1
Davies, AM; Jones, RM; Lim, CK; Martin, EA; Smith, LL; White, IN1
Dwivedy, I; Katzenellenbogen, JA; O'Neil, JP; Ray, S; Tandon, A; Wilson, SR1
Hemminki, K; Mäntylä, E; Rajaniemi, H1
Cattaneo, M1
Carmichael, PL; Cole, KJ; Davis, W; Hewer, A; Horton, MN; Osborne, MR; Phillips, DH1
Ho, SM; LaSpina, M; Lau, KM; Long, J1
Boek-Dohalská, L; Hodek, P; Stiborová, M; Sulc, M1
Agouridas, V; Blazejewski, JC; Cleeren, A; Kizilian, E; Laïos, I; Leclercq, G; Magnier, E1
Chen, T; Fang, Q; Kadam, S; Labow, M; Lei, H; Lewis, T; Li, E; Lohmann, F; Loureiro, J; Su, H; Yang, Y1
Flockhart, DA; Huang, TH; Huang, Y; Li, L; Liu, Y; Nephew, KP; Shen, C; Skaar, TC; Teng, M; Wang, G; Wang, Y; Wang, Z; Yan, P; Zhao, Y1
He, J; Nguyen, AT; Taranova, O; Zhang, Y1
Kang, KW; Kim, SK; Kwak, HC; Lee, JY; Oh, SJ; Phuong, NT; Ryu, CS1
Csabai, K; Fenyvesi, É; Malanga, M; Szemán, J; Szente, L1
Lawrence, HR; Lawrence, NJ; Mahajan, K; Mahajan, NP1
He, W; Liu, R; Yang, SH; Yuan, F1
Floer, M; Gjidoda, A; McAndrew, MJ; Tagore, M1
Agger, K; Helin, K; Johansen, JV; Kooistra, SM; Miyagi, S; Pedersen, MT1
Kim, SS; Lee, MH; Lee, MO1
Chan, YC; Chen, DR; Chen, Y; Hsu, KW; Liu, YE; Wang, YF; Wu, HT1
Bade, D; Dai, X; Gonzalez, G; Huang, M; Li, L; Liu, X; Miao, W; Sun, Y; Wang, Y; Yuan, J1
Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; Arshad, A; Charles, S; Madhavan, T; Mala, K; Munusamy-Ramanujam, G; Saraswathi, NT; Singh, P1
Emami Razavi, A; Jahangiri, R; Jamialahmadi, K; Mosaffa, F; Teimoori-Toolabi, L1
Hamada, Y; Inada, E; Iseki, M; Katsuda, Y; Kondo, T; Kuzumaki, N; Matsufuji, M; Mori, T; Narita, M; Sato, D; Takeshima, H; Tanaka, K; Ushijima, T; Yamabe, Y; Yamaguchi, K1
Hu, C; Hu, M; Li, Z; Ma, S; Wang, M; Xiao, W; Yang, B; Zhou, M; Zhou, Q1

Reviews

1 review(s) available for isomethyleugenol and tamoxifen

ArticleYear
Hyperhomocysteinemia, atherosclerosis and thrombosis.
    Thrombosis and haemostasis, 1999, Volume: 81, Issue:2

    Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12

1999

Other Studies

28 other study(ies) available for isomethyleugenol and tamoxifen

ArticleYear
Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Immunoblotting; Kinetics; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating; Oxygenases; Rabbits; Tamoxifen; Testosterone

1991
Transcriptional control of thymidine kinase gene expression by estrogen and antiestrogens in MCF-7 human breast cancer cells.
    The Journal of biological chemistry, 1986, Apr-25, Volume: 261, Issue:12

    Topics: Amanitins; Breast Neoplasms; Cell Cycle; Cell Line; DNA; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation; Humans; Methylation; Pyrrolidines; RNA; RNA, Messenger; Tamoxifen; Thiophenes; Thymidine; Thymidine Kinase; Time Factors

1986
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer.
    Cell, 1988, Oct-07, Volume: 55, Issue:1

    Topics: Binding Sites; Cell Line; Chromosome Deletion; DNA; DNA Probes; Estradiol; Humans; Ligands; Macromolecular Substances; Methylation; Receptors, Estrogen; Tamoxifen

1988
Pyrimidinones. 3. N-substituted 6-phenylpyrimidinones and pyrimidinediones with diuretic/hypotensive and antiinflammatory activity.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Arthritis; Diuresis; Dose-Response Relationship, Drug; Female; Furosemide; Guanethidine; Heart; Hydrochlorothiazide; Hypotension; Male; Methylation; Natriuresis; Phenylacetates; Potassium; Pyrimidinones; Rats; Rats, Inbred Strains; Stilbenes; Structure-Activity Relationship; Tamoxifen

1986
No loss of estrogenic or anti-estrogenic activity after demethylation of droloxifene (3-OH-tamoxifen).
    International journal of cancer, 1985, Dec-15, Volume: 36, Issue:6

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Estrogen Antagonists; Female; Humans; Methylation; Rats; Receptors, Estrogen; Tamoxifen; Uterus

1985
Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: Animals; Biotransformation; Cattle; DNA Adducts; DNA Damage; Horseradish Peroxidase; Methylation; Protein Binding; Serum Albumin, Bovine; Tamoxifen; Toremifene

1995
An X-ray crystallographic study of the nonsteroidal contraceptive agent centchroman.
    Journal of medicinal chemistry, 1994, Mar-04, Volume: 37, Issue:5

    Topics: Centchroman; Crystallization; Crystallography, X-Ray; Estradiol; Iodides; Methylation; Molecular Conformation; Molecular Structure; Nafoxidine; Receptors, Estrogen; Stereoisomerism; Tamoxifen

1994
DNA adduct formation by tamoxifen and structurally-related compounds in rat liver.
    Chemico-biological interactions, 1998, May-15, Volume: 113, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Liver; Methylation; Phosphates; Rats; Rats, Sprague-Dawley; Tamoxifen

1998
N-demethylation accompanies alpha-hydroxylation in the metabolic activation of tamoxifen in rat liver cells.
    Carcinogenesis, 1999, Volume: 20, Issue:10

    Topics: Animals; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Hydroxylation; Liver; Methylation; Oxidation-Reduction; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Tamoxifen

1999
Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Cell Culture Techniques; Cell Division; Cells, Cultured; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Fulvestrant; Humans; Male; Methylation; Oligonucleotides, Antisense; Prostate; Prostatic Neoplasms; Protein Biosynthesis; Proteins; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

2000
alpha-Naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6.
    Chemico-biological interactions, 2001, Oct-25, Volume: 138, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Estradiol; Hydroxylation; Male; Methylation; Microsomes, Liver; Rabbits; Recombinant Proteins; Tamoxifen

2001
Loss of antagonistic activity of tamoxifen by replacement of one N-methyl of its side chain by fluorinated residues.
    Bioorganic & medicinal chemistry, 2006, Nov-15, Volume: 14, Issue:22

    Topics: Cell Line, Tumor; Cell Proliferation; Estrogen Antagonists; Fluorine; Humans; Methylation; Molecular Structure; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Transcription Factor AP-1; Transcription, Genetic

2006
KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation.
    Stem cells (Dayton, Ohio), 2010, Volume: 28, Issue:2

    Topics: Animals; Cell Differentiation; Cells, Cultured; Chromatin Immunoprecipitation; Embryonic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Immunoblotting; Methylation; Mice; Oligonucleotide Array Sequence Analysis; Protein Methyltransferases; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen

2010
A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer.
    BMC systems biology, 2011, May-09, Volume: 5

    Topics: Bayes Theorem; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epigenesis, Genetic; Estrogen Receptor alpha; Gene Regulatory Networks; Genomics; Histones; Humans; Lysine; Methylation; Models, Genetic; Reproducibility of Results; RNA Polymerase II; Tamoxifen; Time Factors

2011
Essential role of DOT1L in maintaining normal adult hematopoiesis.
    Cell research, 2011, Volume: 21, Issue:9

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Estrogen Antagonists; Hematopoiesis; Histone-Lysine N-Methyltransferase; Histones; Methylation; Methyltransferases; Mice; Mice, Knockout; Recombination, Genetic; Tamoxifen

2011
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
    Biochemical pharmacology, 2013, Jan-15, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation

2013
Methyl-beta-cyclodextrins: the role of number and types of substituents in solubilizing power.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:5

    Topics: Amiodarone; beta-Cyclodextrins; Cholesterol; Chromatography, High Pressure Liquid; Fatty Acids; Furosemide; Isomerism; Magnetic Resonance Spectroscopy; Methylation; Solubility; Tamoxifen

2014
ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1.
    The Journal of biological chemistry, 2014, Oct-10, Volume: 289, Issue:41

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Jumonji Domain-Containing Histone Demethylases; Luciferases; Mammary Glands, Human; Methylation; Models, Molecular; Molecular Sequence Data; Neuregulin-1; Protein Binding; Protein-Tyrosine Kinases; Pyrimidines; Receptor, ErbB-2; Signal Transduction; Tamoxifen; Thiazoles; Transcription, Genetic

2014
Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electron Transport Complex I; Glioma; Humans; Male; Methylation; Mitochondria; Promoter Regions, Genetic; Rats, Sprague-Dawley; Tamoxifen; Temozolomide; Tumor Suppressor Proteins

2015
The Lineage-Specific Transcription Factor PU.1 Prevents Polycomb-Mediated Heterochromatin Formation at Macrophage-Specific Genes.
    Molecular and cellular biology, 2015, Volume: 35, Issue:15

    Topics: Animals; Cell Differentiation; Cell Line; Female; Heterochromatin; Histones; Interleukin-12 Subunit p40; Interleukin-1alpha; Lipopolysaccharides; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Nucleosomes; Pluripotent Stem Cells; Polycomb Repressive Complex 2; Protein Binding; Proto-Oncogene Proteins; Receptors, Estrogen; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Tamoxifen; Trans-Activators; Transcription, Genetic

2015
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.
    Genes & development, 2016, 06-01, Volume: 30, Issue:11

    Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Interleukin-3 Receptor alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Knockout; Protein Binding; Tamoxifen

2016
Histone methyltransferases regulate the transcriptional expression of ERα and the proliferation of tamoxifen-resistant breast cancer cells.
    Breast cancer research and treatment, 2020, Volume: 180, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Humans; Methylation; RNA, Small Interfering; Tamoxifen

2020
MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway.
    The American journal of Chinese medicine, 2020, Volume: 48, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Luteolin; Methylation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; Tamoxifen; TOR Serine-Threonine Kinases

2020
Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m
    Molecular therapy : the journal of the American Society of Gene Therapy, 2020, 12-02, Volume: 28, Issue:12

    Topics: Adenosine; Adenylate Kinase; Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; MCF-7 Cells; Methylation; Methyltransferases; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tamoxifen; Transfection

2020
Pharmacologic downregulation of protein arginine methyltransferase1 expression by adenosine dialdehyde increases cell senescence in breast cancer.
    European journal of pharmacology, 2021, Jan-15, Volume: 891

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Betaine-Homocysteine S-Methyltransferase; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Molecular Docking Simulation; Oxidative Stress; Phosphatidylethanolamine N-Methyltransferase; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Repressor Proteins; Signal Transduction; Tamoxifen

2021
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:2

    Topics: Breast Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; Female; Humans; Methylation; Neoplasm Recurrence, Local; Nuclear Receptor Coactivator 3; PAX2 Transcription Factor; Promoter Regions, Genetic; Tamoxifen

2022
Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery.
    Molecular brain, 2021, 09-20, Volume: 14, Issue:1

    Topics: Animals; Annexins; Benzazepines; Cornified Envelope Proline-Rich Proteins; Disease Models, Animal; Electrocoagulation; Female; Foot Injuries; Gene Expression Regulation; Gene Knock-In Techniques; Genes, fos; Genes, Reporter; Histone Code; Histones; Hyperalgesia; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuralgia; Neurons; Pain, Postoperative; Pyrimidines; RNA, Messenger; Spinal Cord; Tamoxifen

2021
Genistein induces endocrine resistance in human breast cancer by suppressing H3K27 trimethylation.
    Endocrine-related cancer, 2023, Feb-01, Volume: 30, Issue:2

    Topics: Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estrogens; Female; Genistein; Histones; Humans; Interleukin-6; Interleukin-8; Methylation; Receptor, ErbB-2; Tamoxifen

2023