isomethyleugenol has been researched along with s-adenosylmethionine in 1292 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 548 (42.41) | 18.7374 |
| 1990's | 215 (16.64) | 18.2507 |
| 2000's | 162 (12.54) | 29.6817 |
| 2010's | 287 (22.21) | 24.3611 |
| 2020's | 80 (6.19) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, S; Lee, HW; Paik, WK | 2 |
| Baldessarini, RJ | 1 |
| Aboul-Enein, HY; Hulsey, BS; Lindsay, RH | 1 |
| Agrup, G; Falck, B; Hansson, C; Rorsman, H; Rosengren, AM; Rosengren, E | 1 |
| Matthysse, S | 1 |
| Axelrod, J; Hirata, F; Strittmatter, WJ | 2 |
| Furuichi, Y; Miura, K | 1 |
| Moss, B; Wei, CM | 2 |
| Abraham, G; Banerjee, AK; Rhodes, DP | 1 |
| Honma, S; Nambara, T | 2 |
| Banerjee, AK; Rhodes, DP | 1 |
| Ghosh, HP; Toneguzzo, F | 1 |
| Furuichi, Y; Shatkin, AJ | 1 |
| Banerjee, AK; Testa, D | 1 |
| Bhattacharya, A; Vonderhaar, BK | 2 |
| Marín-Cao, D; Mato, JM | 1 |
| Arigoni, D | 1 |
| Kredich, NM; Pike, MC; Snyderman, R | 2 |
| Baxter, CS; Byvoet, P; Sayre, DF | 1 |
| Glazer, RI; Peale, AL | 1 |
| Pegg, AE | 2 |
| Debov, SS; Lopatina, NG; Nikol'skaia, II | 1 |
| Cheh, A; Dizikes, LJ; Lakowicz, JR; Rakow, S; Ridley, WP; Wood, JM | 1 |
| Kanduc, D | 1 |
| Furuichi, Y | 2 |
| Mertens, PP; Payne, CC | 1 |
| Bickle, TA; Brack, C; Yuan, R | 1 |
| Benesh, FC; Carl, GF | 1 |
| Lark, C | 1 |
| Adler, J; Goy, MF; Springer, MS; Szmelcman, S | 1 |
| Koshland, DE; Paoni, NF | 1 |
| Adler, J; Hobson, AC; Kleene, SJ | 1 |
| Bidard, JN; Cronenberger, L | 1 |
| Arber, W | 1 |
| Baldessarini, RJ; Lipinski, JF; Stramentinoli, G | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR | 1 |
| Burdon, RH; Cato, AC | 1 |
| Furuichi, Y; Morgan, MA; Shatkin, AJ | 1 |
| Johnston, JM; Kredich, NM | 1 |
| Mozzi, R; Porcellati, G | 1 |
| Basnak'ian, AG; Khodarev, NN; Sokolov, NN; Votrin, II | 1 |
| Cashaw, JL; Davis, VE; McMurtrey, KD; Meyerson, LR | 1 |
| Garrels, JI; Hunter, T | 1 |
| Brown, GE; Desrosiers, RC; Lebleu, B; Lengyel, P; Sen, GC; Shaila, S | 1 |
| Acierno, P; Errera, M; Giudice, G; Pirrone, AM; Spinelli, G | 1 |
| Balemans, MG; Bary, FA; Noordegraaf, EM; van Berlo, MF | 1 |
| Bajszár, G; Molnár, J; Simoncsits, A; Szabó, G | 1 |
| Reilly, MA; Schayer, RW | 1 |
| Liew, CC; Suria, D | 1 |
| Agnoli, A; Andreoli, VM; Fazio, C | 1 |
| Ordonez, LA; Wurtman, RJ | 2 |
| Maffei, F; Stramentinoli, G | 1 |
| Agnoli, A; Casacchia, M; Squitieri, G | 1 |
| Agnoli, A; Carolei, A; Meco, G | 1 |
| Agnoli, A; Arrigoni, E; Benzi, G; Villa, RF | 1 |
| Axelrod, J; Hirata, F | 2 |
| Akesson, B | 2 |
| Caboche, M; Hatzfeld, J | 1 |
| Benesh, FC; Carl, GF; Hudson, JL | 1 |
| Agnoli, A; Andreoli, V; Bonamini, F; Carolei, A; Casacchia, M; Cerbo, R; De Carolis, V; Fazio, C; Pastorino, P; Ruggieri, S | 1 |
| Friedhoff, AJ; Rosengarten, H | 1 |
| Nau, F | 1 |
| Delk, AS; Rabinowitz, JC | 1 |
| Ando, T; Shibata, T | 1 |
| Arnold, HH; Kersten, H; Schmidt, W | 1 |
| Cox, R; Irving, CC | 1 |
| Balis, ME; Maschio, FA; Tscherne, JS; Wainfan, E | 1 |
| Banerjee, AK; Black, LM; MacLeod, R; Reddy, DV; Rhodes, DP | 1 |
| Frère, J | 1 |
| Dizikes, LJ; Ridley, WP; Wood, JM | 1 |
| Nuss, DL; Paoletti, E | 1 |
| Carter, CA | 1 |
| Farris, DA; Levin, KH; Samuel, CE | 1 |
| Kovar, KA; Maslinski, S; Schippert, B; Sewing, KF | 1 |
| Kwok, ML; Lo, CM; Wurtman, RJ | 1 |
| Boarder, MR; Oon, MC; Rodnight, R | 1 |
| Kudriashova, IB; Vaniushin, BF | 1 |
| Furuichi, Y; Morgan, M; Muthukrishnan, S; Shatkin, AJ | 1 |
| Lin, RL; Narasimhachari, N | 3 |
| Groner, Y; Hurwitz, J | 1 |
| Dudock, B; Marcu, K | 1 |
| Chheda, GB; Chu, J; Wainfan, E | 1 |
| Cantoni, GL | 2 |
| de Robichon-Szulmajster, H; Feldmann, H; Fesneau, C; Fradin, A | 1 |
| Hansen, S; Krueger, DH; Presber, W; Rosenthal, HA | 1 |
| Reeves, RH; Roth, JR | 1 |
| Friedhoff, AJ; Meller, E; Rosengarten, H; Silber, R; Stebbins, RD | 1 |
| Schatz, RA; Sellinger, OZ | 1 |
| Randall, PK; Taylor, KM | 1 |
| Huszar, G | 2 |
| Jimenez, C; Municio, AM; Suarez, A | 1 |
| Both, GW; Furuichi, Y; Muthukrishnan, S; Shatkin, AJ | 1 |
| Swann, PF | 1 |
| Fuentes, JA; Neff, NH; Oleshansky, MA | 1 |
| Schayer, RW | 1 |
| Barbier, M; Kerr, SJ; Lederer, E; Tekitek, A | 1 |
| Friedhoff, AJ; Meller, E; Rosengarten, H | 1 |
| Buehring, YS; Poirier, LA; Stokstad, EL | 1 |
| Keating, JN; Kennedy, DG; Kennedy, S; Molloy, AM; Scott, JM; Weir, DG; Young, PB | 1 |
| Demarty, M; Morvan, C; Thoiron, B; Vannier, MP | 1 |
| Koob, M | 1 |
| Kiss, A; Szilák, L; Venetianer, P | 1 |
| Aarbakke, J; Andersen, A; Loennechen, T; Moens, U; Nilsen, IW | 1 |
| Andriamampandry, C; Kanfer, JN; Massarelli, R | 1 |
| Béliveau, R; Gingras, D | 1 |
| Danzitz, MJ; Reich, NO | 1 |
| Finn, KA; Johnson, JA; Siegel, FL | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Tuck, MT | 1 |
| Akino, T; Hashimoto, H; Ohguro, H; Sohma, H | 1 |
| Cobuzzi, RJ; Collins, MA; Matsubara, K; Neafsey, EJ; Rollema, H | 1 |
| Köhler, T; McBride, MJ; Zusman, DR | 1 |
| Collins, MA; Matsubara, K; Neafsey, EJ | 1 |
| Keating, JN; Mulcahy, F; Scott, JM; Trimble, KC; Weir, DG | 1 |
| Ghosh, SK; Kim, SD; Paik, WK; Rawal, N; Syed, SK | 1 |
| Akerman, K; Eloranta, TO; Harvima, RJ; Kajander, EO; Kantola, M; Kärenlampi, SO; Martikainen, H | 1 |
| Dreyfus, H; Ferret, B; Hubsch, A; Massarelli, R | 1 |
| Sellinger, OZ; Wolfson, MF | 1 |
| Otero Losada, ME; Rubio, MC | 1 |
| Miller, JW; Selhub, J | 1 |
| Borot, C; Lawrence, F; Moulay, L; Phelouzat, MA; Robert-Gero, M; Schaeverbeke, J; Schaeverbeke, M | 1 |
| Chagoya de Sánchez, V; Hernández-Muñoz, R; Sánchez, L; Suárez, J; Vidrio, S; Yáñez, L | 1 |
| Aswad, DW; Johnson, BA; Najbauer, J | 1 |
| Clarke, S; Ingrosso, D | 1 |
| Béliveau, R; Gingras, D; Ménard, P | 1 |
| Dai, J; Dhalla, NS; Mesaeli, N; Panagia, V; Vetter, R | 1 |
| Carl, GF; Eto, I; Furman, GM; Krumdieck, CL; Schatz, RA; Smith, ML | 1 |
| Dirheimer, G; Keith, G; Pfohl-Leszkowicz, A | 1 |
| Davis, BA; Durden, DA; Yu, PH | 1 |
| Kanungo, MS; Saran, S | 1 |
| Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW | 2 |
| Hyland, K; Smith, I; Surtees, R | 1 |
| Floss, HG; Ho, DK; Santi, DV; Wu, JC | 1 |
| Friedman, S; Som, S | 2 |
| Isobe, R; Kang, D; Minakami, S; Takeshige, K | 1 |
| Edelstein, SR; Gross, LA; Johnson, MA; Richardson, BC; Scheinbart, LS | 1 |
| Bonkovsky, HL; Chawla, RK; Galambos, JT | 1 |
| Fraher, LJ; McFadden, RG | 1 |
| Clarke, S; Fung, BK; Ota, IM; Yamane, HK | 1 |
| Desrosiers, RR; O'Connor, CM; Romanik, EA | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V; Taira, Y; Tung, S | 1 |
| Cordier, G; Fonlupt, P; Gormand, F; Pacheco, Y; Revillard, JP | 1 |
| Benistant, C; Fonlupt, P; Rey, C | 1 |
| Betts, WH; French, JK; Hurst, NP | 1 |
| Lyn-Cook, B; Poirier, LA; Zapisek, W | 1 |
| Bergerat, A; Guschlbauer, W | 1 |
| Mashiko, M; Takahashi, K; Yamamura, Y; Yamauchi, H | 1 |
| England, RE; Franks, JJ; Sastry, BV; Surber, MJ | 1 |
| Blanche, F; Debussche, L; Thibaut, D | 1 |
| Hughes, P; Kern, R; Kohiyama, M; Landoulsi, A; Malki, A | 1 |
| Bottiglieri, T | 2 |
| Akerman, KK; Harvima, RJ; Kajander, EO; Kärenlampi, SO; Kauppinen, L; Martikainen, H; Pajula, RL | 1 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Lawen, A; Zocher, R | 1 |
| Aswad, DW; Najbauer, J | 1 |
| Dai, J; Dhalla, NS; Panagia, V; Vetter, R | 1 |
| White, RH | 1 |
| Caldwell, DC; Emerson, CP | 1 |
| Bjorndahl, JM; Rutledge, CO | 1 |
| Carney, MW | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 2 |
| Waickus, CM; Young, PR | 1 |
| Vacante, DA; Waickus, CM; Young, PR | 1 |
| Denoya, CD; Dubnau, D | 1 |
| Benyon, RC; Church, MK; Hughes, PJ | 1 |
| Grynspan, F; Young, PR | 1 |
| Daino, L; Feo, F; Garcea, R; Pascale, R; Puddu, M; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Bezstarosti, K; Lamers, JM; Meij, JT; Panagia, V; Paolillo, G; Verdouw, PD | 1 |
| Carotti, D; Lavia, P; Palitti, F; Strom, R | 1 |
| Durbin, RK; Scheidel, LM; Stollar, V | 1 |
| LeBel, CP; Schatz, RA | 1 |
| Nègre, D; Ofengand, J; Weitzmann, C | 1 |
| Aswad, DW | 2 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Bjur, RA; Greenhouse, AH; Mead, DJ; Reitz, RC; Welch, WH | 1 |
| Gharib, A; Greenland, T; Hamidi, J; Khatchadourian, C; Menezo, Y; Sarda, N | 1 |
| Iardino, P; Libondi, T; Manna, C; Nuzzolillo, L | 1 |
| Hammond, DC; Lesnaw, JA | 1 |
| Doolittle, MM; Sirotkin, K | 1 |
| Brasitus, TA; Brown, MD; Dudeja, PK | 1 |
| Banerjee, RV; Dunham, WR; Frasca, V; Matthews, RG; Sands, RH | 1 |
| Ozawa, K; Segawa, T | 2 |
| Aswad, DW; Johnson, BA; Shirokawa, JM | 1 |
| Audubert, F; Bereziat, G; Breton, M; Colard, O | 1 |
| Allen, PT; Hernandez, L; Lijinsky, W; Poirier, LA | 1 |
| Dhalla, NS; Makino, N; Okumura, K; Panagia, V | 1 |
| Neri, G; Zollino, M | 1 |
| Jaffe, JJ; Srivastava, AK | 1 |
| Dubois, M; Fougier, S; Némoz, G; Pacheco, H; Prigent, AF | 1 |
| Pike, MC; Snyderman, R | 2 |
| Boss, GR; Erbe, RW; Levitt, LJ | 1 |
| Marver, D | 1 |
| Brasitus, TA; Dudeja, PK; Foster, ES | 2 |
| Ermil'chenko, GV; Fedorov, NA | 1 |
| Carreau, S; Drosdowsky, MA; Kamtchouing, P; Papadopoulos, V | 1 |
| Bickle, TA; Price, C; Pripfl, T | 1 |
| Freeze, HH; Wolgast, D | 1 |
| Galletti, P; Iardino, P; Ingrosso, D; Manna, C; Pontoni, G; Zappia, V | 1 |
| Bonvini, E; Herberman, RB; Hoffman, T; Varesio, L | 1 |
| Allen, ER; Freese, E; Orrego, C; Wabiko, H | 1 |
| Amidei, K; Barber, M; Byvoet, P; Lowell, N; Trudeau, W | 1 |
| Carl, GF | 1 |
| Fell, D; Steele, RD | 1 |
| Coombs, GH; Sanderson, BE; Thong, KW | 1 |
| Osborne, HB; Papazafiri, P | 1 |
| Siegel, FL; Vincent, PL | 1 |
| Benevenga, NJ; Engstrom, MA | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V; Taira, Y | 1 |
| Piekarowicz, A; Stein, DC; Yuan, R | 1 |
| Dhalla, NS; Ganguly, PK; Okumura, K; Panagia, V | 1 |
| Neal, TL; Siegel, FL; Wright, LS | 1 |
| Aksamit, RR; Backlund, PS | 2 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Bloch, K; Chin, J | 1 |
| Brown, LR; Ferro, AJ; Hughes, JA | 1 |
| Hancock, RL | 3 |
| Snoswell, AM; Xue, GP | 2 |
| Hardy, LW; Santi, DV | 1 |
| Hariyama, H; Moriguchi, K; Sato, H | 1 |
| Ben-Baruch, G; Kloog, Y; Menczer, J; Solomon, R | 1 |
| Philipson, KD; Vemuri, R | 1 |
| Liteplo, RG | 1 |
| Ibrahim, RK; Khouri, HE; Tahara, S | 1 |
| Liteplo, RG; Munro, S | 1 |
| Kramer, CM; Sellinger, OZ | 1 |
| Don, HS; Shiao, MS | 1 |
| Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Gross, P; Minuth, WW; Steckelings, U | 1 |
| Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Bollag, GE; Koshland, DE; Sternberg, DW; Terwilliger, TC | 1 |
| Stipanuk, MH | 1 |
| Santi, DV; Wu, JC | 2 |
| Hoffman, JL; McConnell, KP | 1 |
| Fonlupt, P; Pacheco, H; Rey, C | 3 |
| Rowe, PM; Siegel, FL; Wright, LS | 1 |
| Brasitus, TA; Dudeja, PK | 1 |
| Clarke, S; Ding, L; Ota, IM | 1 |
| Black, MT; Cramer, WA; Meyer, D; Widger, WR | 1 |
| Germain, BJ; O'Connor, CM | 1 |
| Cavaignac, S; Coira, JA; Ugalde, RA | 1 |
| Feldtrauer, JJ; Waldmeier, PC | 1 |
| Baker, DJ; Hardy, TA; Smith, SS | 1 |
| Lakher, MB; Wurtman, RJ | 1 |
| Liu, MS; Yang, Y | 1 |
| Colby, HD; LaCagnin, LB; Lutsie, P | 1 |
| Lakher, M; Wurtman, RJ | 1 |
| Dainous, F; Kanfer, JN | 1 |
| Sulser, F; Zawad, JS | 1 |
| Loo, G; Smith, JT | 1 |
| Crooks, PA; Damani, LA; Godin, CS; Nwosu, C; Shaker, MS | 1 |
| Torsten, U | 1 |
| Marafante, E; Vahter, M | 1 |
| Bechet, JJ; Clauser, H; Drouva, SV; Kordon, C; LaPlante, E; Leblanc, P | 1 |
| Cresteil, D; Lemonnier, A; Lemonnier, F; Ozturk, M | 1 |
| Huszti, Z; Tyihák, E | 1 |
| Egozi, Y; Kloog, Y; Meydan, N | 1 |
| Dellacha, JM; Podestá, EJ; Sánchez, ML; Solano, AR; Turyn, D | 1 |
| Kufe, DW; Shafman, TD; Sherman, ML; Spriggs, DR | 1 |
| Samet, MK | 1 |
| Dellacha, JM; Scacchi, GE; Turyn, D | 1 |
| Bloch, K; Chin, J; Kawasaki, S; Ramgopal, M | 1 |
| Borchardt, RT; Clark, RS; Keller, BT; Pegg, AE | 1 |
| Harvey, SE; Hatch, R; Williams-Ashman, HG | 1 |
| Pastuszko, A; Rafałowska, U | 1 |
| Edwards, RM; Greeley, GH; Mori, M; Pegues, J; Prasad, C; Wilber, JF | 1 |
| Nuske, JH | 1 |
| Bergo, CH; Blake, JW; Flesher, JW; Myers, SR | 1 |
| Crooks, PA; Cundy, KC; Godin, CS | 1 |
| Duerre, JA; Wallwork, JC | 1 |
| Bansal, VS; Kanfer, JN | 1 |
| Bubenshchikova, SN; Burtseva, NN; Gimadutdinov, OA; Vaniushin, BF | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V | 1 |
| Barone, S; de la Lande, IS; Head, RJ; Irvine, RJ; Stitzel, RE | 1 |
| Aswad, DW; Johnson, BA | 2 |
| Buchet, JP; Lauwerys, R | 1 |
| Aswad, DW; Freitag, NE; Johnson, BA | 1 |
| Magruder, JD; Reitz, RC; Waid-Jones, M | 1 |
| Chaffee, S; Greenberg, ML; Hershfield, MS; Kurtzberg, J | 1 |
| Duerre, JA; Fetters, HA; Kelleher, J | 1 |
| van der Westhuyzen, J | 1 |
| Gill, MW; Schatz, RA | 1 |
| Jones, PA; Kautiainen, TL | 1 |
| Young, DL | 1 |
| Baxter, JH; Beaven, MA; Horáková, Z | 1 |
| Laduron, P; Leysen, J | 2 |
| Carnegie, PR; Jones, GM | 1 |
| Barchas, JD; Barchas, R; Ciaranello, RD; Kessler, S | 1 |
| Gonnard, P | 1 |
| Bolt, HM; Kappus, H | 1 |
| Cossins, EA; Lor, KL | 1 |
| Christensen, NJ | 1 |
| Krüger, FW; Rücker, U; Wiessler, M | 1 |
| Blaschke, E; Hertting, G | 2 |
| Cier, JF; Pérés, G; Peyrin, L | 1 |
| Breier, B; Holley, RW | 1 |
| Gallagher, RE; Gallo, RC; Ting, RC | 1 |
| Lee, HW; Morris, HP; Paik, WK | 1 |
| Laduron, P | 3 |
| Burdon, RH; Pearce, CA | 1 |
| Thompson, W; Wong, ER | 1 |
| Granieri, A; Scarano, E; Tosi, L | 1 |
| Kerr, SJ | 1 |
| al-Arif, A; Sporn, MB | 1 |
| Klagsbrun, M | 2 |
| Sharma, OK | 1 |
| Kerr, SJ; Wilkinson, R | 1 |
| Boyer, HW; Dugaiczyk, A; Goodman, HM; Hedgpeth, J | 1 |
| Baxter, CS; Byvoet, P | 2 |
| Banerjee, AK; Moyer, SA; Rhodes, DP | 1 |
| Edgar, DH; Hope, DB | 1 |
| Houser, RM; Olson, RE; Trumpower, BL | 1 |
| Fehler, SW; Light, RJ | 1 |
| Fuller, RW; Roush, BW | 1 |
| Duerre, JA; Lee, CT | 1 |
| Cory, M; Henry, DW; Koskela, KJ; Taylor, DL | 1 |
| Hamada, M; Kumada, Y; Naganawa, H; Takeuchi, T; Umezawa, H | 1 |
| Ceccato, S; Passeri, M | 2 |
| Axelrod, J; Saavedra, JM; Wyatt, RJ | 1 |
| Shatkin, AJ | 1 |
| Mandel, LR; Walker, RW | 1 |
| Parks, LW; Starr, PR | 1 |
| Bronskill, P; Kennedy, TD; Lane, BG | 1 |
| Friedhoff, AJ; Miller, J; Schweitzer, JW | 2 |
| Berdahl, BJ; Borek, E; Low, M; Schein, A | 1 |
| Borek, E; Kerr, SJ | 1 |
| Haberman, A; Heywood, J; Meselson, M | 1 |
| Pegg, AE; Stewart, BW | 1 |
| Chan, TC; Fraser, MJ | 1 |
| Coch, EH; Greene, RC; Hunter, JS | 1 |
| Isaksson, LA | 1 |
| Banerjee, SP; Snyder, SH | 2 |
| Savitskii, IV; Zelenskii, VG | 1 |
| Dudock, B; Michael, M; Roe, B | 1 |
| Balish, E | 1 |
| Agris, PF; Brown, GM; Rajbhandary, UL; Spremulli, LL | 1 |
| Isham, KR; Stulberg, MP | 1 |
| Saavedra, JM | 1 |
| Shugart, L; Stulberg, MP | 1 |
| Kuchino, Y; Nishimura, S | 1 |
| Blanchard, P; Hildesheim, J; Michelot, R | 1 |
| Bayev, AA; Shershneva, LP; Venkstern, TV | 1 |
| Dirheimer, G; Dubois, EG; Weil, JH | 1 |
| Bouche, JP | 1 |
| Axelrod, J; Saavedra, JM | 1 |
| Lornitzo, FA | 1 |
| Fitzgerald, PJ; Marsh, WH; Mizoguchi, M; Parsa, I | 1 |
| Persson, K | 1 |
| Baliga, BS; Phorecky, LA | 1 |
| Müller-Enoch, D; Roth, S; Thomas, H | 1 |
| Stöhrer, G | 1 |
| Pillinger, DJ | 1 |
| Königk, E; Ossikovski, E; Schmidt, G | 1 |
| Eguchi, Y; Kimata, K; Okuda, S; Takagi, M; Uda, F | 1 |
| Jacob, M; Judes, C | 1 |
| Kakimoto, Y; Miyake, M | 1 |
| Liss, M; Morin, AM | 1 |
| Borun, TW; Lee, HW; Paik, WK | 1 |
| Rigoli, A | 1 |
| Dengler, HJ; Gugler, R; Hengstmann, JH | 1 |
| Cohn, CK; Dunner, DL; Weinshilboum, RM; Wyatt, RJ | 1 |
| Cashaw, JL; Collins, AC; Davis, VE | 1 |
| Cushley, RJ; Scott, AI; Townsend, CA | 1 |
| Borchardt, RT | 2 |
| Evans, HH; Evans, TE; Littman, S | 1 |
| McKenzie, GM; White, HL | 1 |
| Degnen, ST; Morris, NR | 1 |
| Collins, MA; Rubenstein, JA | 1 |
| Baldessarini, RJ; Greiner, E | 1 |
| Fujita, T; Suzuoki, Z | 1 |
| Scarano, E; Tosi, L | 1 |
| Adams, RL; Hogarth, C | 1 |
| Betzing, H; LeKim, D; Stoffel, W | 1 |
| Axelrod, J; Kreuz, DS | 1 |
| Acheampong-Mensah, D; Feuer, G | 1 |
| Cocchiara, R; Eremenko, T; Geraci, D; Granieri, A; Scarano, E; Volpe, P | 1 |
| Jensen, LS; Kushwaha, RP | 1 |
| Englert, LF; Gardner, PM; Ho, BT; Walker, KE | 1 |
| Godomski, S; Hancock, RL; McDermott, A | 1 |
| Morris, NR; Pih, KD | 1 |
| Drahovský, D; Morris, NR | 1 |
| Borek, E; Ryan, AM | 1 |
| Kuchino, Y; Nishimura, S; Seno, T | 1 |
| Lane, BG; Nichols, JL | 1 |
| Huang, HH; Johnson, BC; Ma, J | 1 |
| Herrlich, P; Sauerbier, W; Schweiger, M | 1 |
| Taylor, RT; Weissbach, H | 1 |
| Kakimoto, Y | 1 |
| Ball, P; Breuer, H; Haupt, M; Knuppen, R | 2 |
| Roth, S; Thomas, H | 1 |
| Gasbarrini, G; Labò, G; Miglio, F | 1 |
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| Challand, MR; Driesener, RC; Kay, CW; Roach, PL; Salvadori, E; Spencer, J | 1 |
| Laxman, S; Sutter, BM; Tu, BP; Wu, X | 1 |
| Christian, T; Gamper, H; Hou, YM | 1 |
| Dillon, MB; Mowen, KA; Rust, HL; Thompson, PR | 1 |
| Kong, X; Li, L; Li, X; Liang, Z; Lu, J; Luo, C; Ouyang, S; Zhang, R; Zheng, YG; Zhu, K | 1 |
| Cande, WZ; Guan, Q; Hammond, MC; Iavarone, AT; Li, F; Rine, J; Sadhu, MJ; Sales-Lee, J | 1 |
| Arcinas, AJ; Booker, SJ; Landgraf, BJ; Lee, KH | 1 |
| Blum, GJ; Bothwell, IR; Chen, Y; Deng, H; Dong, A; Islam, K; Luo, M; Min, J; Wu, H; Zeng, H; Zheng, W | 1 |
| Garneau-Tsodikova, S; Zolova, OE | 1 |
| Cao, J; Geng, Z; Hu, X; Li, X; Song, X; Wang, S; Wang, Z | 1 |
| Combs, GF; Gabel-Jensen, C; Gammelgaard, B; Jackson, MI; Lunøe, K | 1 |
| Boddy, CN; Carmichael, R; Müller, R; Rachid, S; Stevens, DC; Tan, J; Taylor, RE; Young, J | 1 |
| Blum, G; Chen, Y; Deng, H; Guo, H; Luo, M; Wang, R; Zheng, W | 1 |
| Düttmann, S; Entian, KD; Kötter, P; Sharma, S; Watzinger, P; Yang, J | 1 |
| Laxman, S; Sutter, BM; Tu, BP | 1 |
| Dong, A; Lam, R; Li, Y; Min, J; Schapira, M; Siarheyeva, A; Vedadi, M; Wu, H; Wu, XH; Zeng, H | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Baran, PS; Burns, AC; Collins, MR; Gui, J; Ishihara, Y; Ornelas, MA; Pan, CM; Yabe, Y; Zhou, Q | 1 |
| Moresco, JJ; Rine, J; Sadhu, MJ; Yates, JR; Zimmer, AD | 1 |
| Carrasco, M; Castro, C; Lu, SC; Luka, Z; Martínez-Chantar, ML; Mato, JM; Micó, JA; Murillo-Carretero, M; Ortega-Martínez, S; Rabaneda, LG; Wagner, C; Woodhoo, A | 1 |
| Barroso, M; Blom, HJ; Carlson, BA; Castro, R; de Almeida, IT; Florindo, C; Gladyshev, VN; Handy, DE; Hatfield, DL; Kalwa, H; Loscalzo, J; Michel, T; Silva, Z; Turanov, AA | 1 |
| Caceres, TB; Chen, J; Chen, X; Gong, Q; Hevel, JM; Liu, L; Peng, J; Shi, Y; Teng, M; Wang, C; Wang, J; Wu, J; Zhang, Z; Zhu, Y; Zuo, X | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Levy, D; Liu, X; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V | 1 |
| Meuwly, M; Schmidt, T; Schwede, T | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 1 |
| French, SW; Kharbanda, KK; Orlicky, DJ; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Albasanz, JL; Barrachina, M; Ciruela, F; Díaz-Sánchez, S; Fernández-Dueñas, V; Ferrer, I; Martín, M; Nuñez, F; Taura, J; Villar-Menéndez, I | 1 |
| Armengod, ME; Benítez-Páez, A; Cárdenas-Brito, S; Corredor, M; Villarroya, M | 1 |
| Nandurkar, NS; Singh, S; Thorson, JS | 1 |
| Alzua, BR; Marsh, EN; McClain, AM; Román-Meléndez, GD; Wang, J; Woldring, RP | 1 |
| Benítez-Páez, A; Cárdenas-Brito, S; Corredor, M; Mosquera-Rendón, J; Pineda, JD | 1 |
| Abe, T; Asano, M; Baba, K; Ishikawa, S; Kataoka, R; Kuramata, M; Sakakibara, F; Takagi, K | 1 |
| Crécy-Lagard, Vd; Ikeuchi, Y; Kimura, S; Miyauchi, K; Suzuki, T; Thiaville, PC | 1 |
| Cheng, K; Liu, H; Liu, W; Mao, J; Wang, F; Wang, K; Ye, M; Zhao, ZK; Zhou, YJ; Zou, H | 1 |
| Bing, Y; Guo, T; He, Y; Li, C; Li, T; Liu, Q; Liu, W; Liu, Z; Qi, H; Wang, Y; Yu, G; Yuan, Y; Zhu, S | 1 |
| Sun, GX; Wang, PP; Zhu, YG | 1 |
| Avasarala, S; Bikkavilli, RK; Borowicz, S; Karuppusamy Rathinam, MK; Tauler, J; Van Scoyk, M; Winn, RA | 1 |
| Armstrong, SA; Bradner, JE; Chory, EJ; Dhe-Paganon, S; Federation, AJ; Hadler, M; Marineau, JJ; Qi, J; Smith, WB; Souza, A; St Pierre, R; Varca, AC; Wu, L; Xu, X; Yi, JS | 1 |
| Dahl, HA; Falnes, PØ; Ho, AY; Małecki, J; Moen, A | 1 |
| Chang, J; Geng, Z; Li, X; Song, X; Wang, Z | 1 |
| Drennan, CL; Goldman, PJ; Grell, TA | 1 |
| Jarrett, JT | 2 |
| Abdelwahed, SH; Begley, TP; Cooper, LE; Ealick, SE; Fedoseyenko, D; Jhulki, I; Liu, Y; Mahanta, N; Mehta, AP; Philmus, B | 1 |
| Broderick, JB; Byer, AS; Peters, JW; Shepard, EM | 1 |
| Bauerle, MR; Booker, SJ; Schwalm, EL | 1 |
| Banerjee, R | 1 |
| Nordgren, KK; Skildum, AJ | 1 |
| Kimura, S; Suzuki, T | 1 |
| Bujnicki, JM; Byszewska, M; Purta, E; Śmietański, M | 1 |
| Blanco-González, E; Cinti, M; Fernández de la Campa, MR; Iglesias González, T; Montes-Bayón, M | 1 |
| Chu, Y; Guo, H; Yue, Y | 1 |
| Comstock, LR; Hymbaugh Bergman, SJ | 1 |
| Bandarian, V; Young, AP | 1 |
| Fang, ZP; Liu, RJ; Long, T; Wang, ED; Zhou, M; Zhou, XL | 1 |
| Bertolo, RF; Brunton, JA; Furlong, KR; McBreairty, LE; Robinson, JL | 1 |
| Goto-Ito, S; Hou, YM; Ito, T; Masuda, I; Sekine, S; Suh, SW; Yokoyama, S; Yoshida, K | 1 |
| Blaszczyk, AJ; Booker, SJ; Buller, AR; Grove, TL; Lloyd, EP; Marous, DR; Moshos, KA; Townsend, CA | 1 |
| Hou, YM; Masuda, I | 1 |
| Fujimori, DG; Stojković, V | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Aspichueta, P; Barbier-Torres, L; Beraza, N; Falcon-Perez, JM; Fernandez, ML; Fernández-Ramos, D; Fernandez-Tussy, P; García-Monzón, C; García-Rodríguez, JL; Juan, VG; Lage-Medina, S; Lopitz-Otsoa, F; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Martínez-Uña, M; Mato, JM; Varela-Rey, M; Wagner, C; Woodhoo, A; Zubiete-Franco, I | 1 |
| Ables, G; Bamman, MM; Gómez Padilla, P; Gupta, D; Huang, L; Liu, X; Locasale, JW; Mattocks, D; Mehrmohamadi, M; Mentch, SJ; Nichenametla, SN; Thalacker-Mercer, AE | 1 |
| Andexer, JN; Aschwanden, S; Mordhorst, S; Richter, M; Siegrist, J; Thöny-Meyer, L | 1 |
| Barroso, M; Blom, HJ; Castro, R; Handy, DE; Kao, D; Loscalzo, J; Tavares de Almeida, I | 1 |
| Cheillan, D; Dessein, AF; Dobbelaere, D; Fontaine, M; Joncquel-Chevalier Curt, M; Mention-Mulliez, K; Porchet, N; Soto-Ares, G; Vamecq, J; Voicu, PM | 1 |
| Canard, B; Collet, A; Debart, F; Decroly, E; Grimes, JM; Paesen, GC; Sallamand, C; Vasseur, JJ | 1 |
| Cui, H; Zhao, H; Zheng, C | 1 |
| Hu, G; Hu, H; Huang, Y; Jiang, H; Liang, Z; Luo, C; Patel, VS; Xie, Y; Yu, K; Zhang, J; Zheng, YG; Zhou, R | 1 |
| Battle, SL; Bielas, JH; Blau, CA; Detraux, D; Devi, A; Ericson, NG; Ferreccio, A; Fiehn, O; Fischer, KA; Gu, H; Hawkins, RD; Hesson, J; Hockenbery, D; Margaretha, L; Margineantu, D; Margolin, AA; Mathieu, J; Moon, RT; Raftery, D; Robitaille, AM; Ruohola-Baker, H; Showalter, M; Sperber, H; Valensisi, C; Wang, Y; Ware, CB; Xu, Z | 1 |
| Locasale, JW; Mentch, SJ | 1 |
| Kim, YH; Thanh Mai Pham, L | 1 |
| Albertí, S; Conn, GL; Dammer, EB; Duong, DM; Goldberg, JB; Kuiper, EG; Meisner, J; Owings, JP; Prezioso, SM; Seyfried, NT; Varga, JJ; Zelinskaya, N | 1 |
| Zufferey, R | 1 |
| Basavapathruni, A; Boriack-Sjodin, PA; Copeland, RA; Godbole, A; Gureasko, J; Hermans, W; Leland, PA; Porter Scott, M; Riera, TV; Wigle, TJ | 1 |
| Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y | 1 |
| Gruber, K; Jankowitsch, F; Macheroux, P; Mack, M; Tongsook, C; Uhl, MK | 1 |
| Hou, YM | 1 |
| Bowie, JU; Clarke, SG; Korman, TP; Sherkhanov, S | 1 |
| Deth, R; Hodgson, N; Trivedi, M; Zhang, Y | 1 |
| Hyun, JC; Kunjapur, AM; Prather, KL | 1 |
| Boal, AK; Booker, SJ; Grove, TL; Schwalm, EL | 1 |
| Holbert, M; Hou, W; Matico, RE; McDevitt, PJ; Poulin, MB; Schneck, JL; Schramm, VL | 1 |
| Chen, Y; Chu, Y; Deng, H; Huang, L; Li, W; Liu, D; Liu, ZJ; Ma, J; Ouyang, S; Wang, T; Zhang, Z; Zhu, Y | 1 |
| Doxtader, KA; Nam, Y; Wang, P | 1 |
| Argyrou, A; Burns-Huang, K; Gold, B; Ioerger, TR; Kapilashrami, K; Ling, Y; Little, D; Luo, M; Martinez-Hoyos, M; Meiler, E; Mendoza-Losana, A; Mi, J; Murphy, KC; Nandakumar, M; Nathan, CF; Park, S; Porras-De Francisco, E; Rees, M; Rhee, KY; Roberts, J; Somersan-Karakaya, S; Warrier, T; Zhang, T | 1 |
| Ferguson, SJ | 1 |
| Beom, JY; Kim, DM; Kim, E; Kim, MS; Lee, EY; Nam, SJ; Song, MC; Yoon, YJ | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Chen, Y; McCormick, S; Zou, T | 1 |
| Ebrahimi, M; Fan, X; Jiang, X; Li, X; Niu, L; Qiao, Z; Teng, M; Wang, C; Wang, M; Zhu, Y | 1 |
| Karas Kuželički, N | 1 |
| Clarke, A; Deth, R; Lopez-Toledano, M; Trivedi, M; Zhang, Y | 1 |
| Assaraf, YG; Raz, S; Stark, M | 1 |
| Alkhalaf, LM; Challis, GL; de Los Santos, EL; Zhou, S | 1 |
| Augoustides-Savvopoulou, P; Barić, I; Blom, HJ; Chien, YH; Dobbelaere, D; Grünert, SC; Opladen, T; Petković Ramadža, D; Rakić, B; Staufner, C; Wedell, A | 1 |
| Dong, Y; Gao, Z; Gong, Y; Liu, G; Wang, J; Wang, L; Zhang, H; Zhang, L; Zhao, M | 1 |
| Agrebi, R; Bellows, LE; Collet, JF; Gründling, A; Kaever, V; Zhang, Y | 1 |
| Laurino, P; Tawfik, DS | 1 |
| Fitzsimmons, CM; Fujimori, DG | 1 |
| Benjdia, A; Berteau, O; Chartier, G; Guillot, A; Leprince, J; Parent, A | 1 |
| Blum, G; Bothwell, IR; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, Z | 1 |
| Guo, Y; Xue, X; Yan, Y; Yang, G; Ye, J; Zhu, Y | 1 |
| Chen, F; Deng, Z; Ding, W; Ji, X; Li, Y; Mo, T; Qianzhu, H; Tu, T; Yu, Y; Zhang, Q; Zhao, J | 1 |
| McHardy, SF; Neelakantan, H; Vance, V; Wang, HL; Watowich, SJ | 1 |
| Chen, J; Jiang, X; Li, J; Rosen, BP | 1 |
| Baumgardt, K; Becker, A; Evguenieva-Hackenberg, E; Madhugiri, R; McIntosh, M; Melior, H; Schikora, A; Thalmann, S | 1 |
| Herbst, DA; Maier, T; Storm, PA; Townsend, CA | 1 |
| Angres, IA; Hao, X; Li, H; Zhou, M | 1 |
| Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C | 1 |
| Burley, GA; Humphreys, LD; Sadler, JC; Snajdrova, R | 1 |
| He, MD; Jiang, YL; Li, M; Li, Q; Lu, YH; Mao, L; Wang, X; Yu, ZP; Zhou, Z | 1 |
| Beane, TJ; Koh, CS; Korostelev, AA; Madireddy, R; Zamore, PD | 1 |
| Du, Z; Gao, Y; Luo, Y; Wang, N; Wang, P; Wu, G; Yang, B; Zhang, Y; Zhu, Z | 1 |
| Hu, B; Le, XC; Li, J; Li, XF; Liu, Q; Peng, H; Zhang, H | 1 |
| Chen, B; Conrad, NK; Hunter, OV; Liu, K; Pendleton, KE; Tu, BP; Xie, Y | 1 |
| Deng, X; Pang, P; Wang, Z; Xie, W | 1 |
| Ferreira, AS; Hobley, L; Khomutov, A; Khomutov, M; Kim, SH; Li, B; Michael, AJ; Naidoo, J; Stanley-Wall, NR; Wood, JL | 1 |
| Bratkowski, M; Liu, X; Yang, X | 1 |
| Almabruk, KH; Begley, TP; Ealick, SE; Fenwick, MK; Philmus, B | 1 |
| Eguchi, T; Kim, SY; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| Engler, H; Oliver, P; Porcal, W; Savio, E; Zoppolo, F | 1 |
| Blaszczyk, AJ; Booker, SJ; Ho, JV; Silakov, A; Wang, B | 1 |
| Alegre, S; Kangasjärvi, S; Pascual, J; Rahikainen, M; Trotta, A | 1 |
| Blaszczyk, AJ; Booker, SJ; Wang, RX | 1 |
| Jackman, JE; Krishnamohan, A | 2 |
| Abhishek, S; Nakarakanti, NK; Nivya, MA; Rajakumara, E; Satish, M; Shivani, D; Vani, MV | 1 |
| Badding, ED; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW; Wang, B | 2 |
| Kim, HJ; Liu, HW; Liu, YN; McCarty, RM | 1 |
| Hudson, GA; Mahanta, N; Mitchell, DA; van der Donk, WA; Zhang, Z | 1 |
| Ebina, M; Igarashi, K; Ishigami, Y; Kumagai, S; Matsumoto, M; Muto, A; Ochiai, K; Sato, Y; Shima, H; Suzuki, T | 1 |
| Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF | 1 |
| Cahill, CM; Fava, M; Gao, J; Huang, X; Lamon-Fava, S; Mischoulon, D; Roffman, JL; Rogers, JT | 1 |
| Blaszczyk, AJ; Booker, SJ | 1 |
| Awwad, HM; Eskelund, AR; Geisel, J; Obeid, R; Tillmann, S; Treccani, G; Wegener, G | 1 |
| Lynch, GS; Ryall, JG | 1 |
| Chu, T; Fujimori, DG; Stojković, V; Therizols, G; Weinberg, DE | 1 |
| Bauerle, MR; Booker, SJ; Grove, TL | 1 |
| Kandavelu, P; Packianathan, C; Rosen, BP | 1 |
| Eguchi, T; Hammerschmidt, F; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| McLaughlin, MI; van der Donk, WA | 1 |
| Chang, C; Long, H; Lu, Q; Wang, Z; Zhao, M | 1 |
| Tu, BP; Ye, C | 1 |
| Alberto, JM; Battaglia-Hsu, SF; Coelho, D; Dreumont, N; Gauchotte, G; Ghemrawi, R; Guéant, JL; Hergalant, S; Houlgatte, R; Jung, M; Mosca, P; Ndiongue, M; Paoli, J; Quadros, EV; Robert, A; Sequeira, JM; Umoret, R | 1 |
| Blaesi, EJ; Blaszczyk, AJ; Booker, SJ; Knox, HL; Krebs, C; Wang, B; Wang, RX; Zhou, S | 1 |
| Wang, SC | 1 |
| Begley, TP; Müller, R; Schnell, B; Wang, Y | 1 |
| Domik, D; Kai, M; Lemfack, MC; Magnus, N; Piechulla, B; von Reuss, S; Weise, T | 1 |
| Loring, HS; Thompson, PR | 1 |
| Aebi, M; Bleiziffer, P; Freeman, MF; Imani, AS; Krausbeck, F; Künzler, M; Naismith, JH; Riniker, S; Shiran, SL; Sieber, R; Song, H; van der Velden, NS; Zach, C | 1 |
| Saez, DA; Tuñón, I; Vöhringer-Martinez, E; Zinovjev, K | 1 |
| Bitton, R; Feldman, M; Kublanovsky, M; Levy, D; Morgenstern, D; Shmidov, Y; Weil, LE | 1 |
| Conrad, NK; Doxtader, KA; Nam, Y; Scarborough, AM; Seo, D; Wang, P | 1 |
| Nair, SK; Ongpipattanakul, C | 1 |
| Brown, T; Fulton, MD; Zheng, YG | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Sodeoka, M; Sohtome, Y | 1 |
| Chouhan, BPS; Gade, M; Laurino, P; Maimaiti, S | 1 |
| Booker, SJ; Lamb, AL; McFarlane, JS; Prisinzano, TE; Ronnebaum, TA | 1 |
| Ke, C; Rensing, C; Xiong, H; Yang, S; Zhang, G; Zhang, Z; Zhao, C; Zhao, X | 1 |
| McErlean, M; Overbay, J; Van Lanen, S | 1 |
| Albrecht, LV; Bui, MH; De Robertis, EM | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C; Yu, Y; Zhao, X | 1 |
| Arai, T; Ishiguro, K; Suzuki, T | 1 |
| Christensen, HB; Christensen, U; Du, B; Feist, AM; Hansen, ASL; Herrgård, MJ; Jensen, MK; Keasling, JD; Kristensen, M; Luo, H; Özdemir, E; Palsson, BO; Schneider, K; Yang, L | 1 |
| Dawczynski, C; Gabel, A; Große, I; Henze, A; Hirche, F; Kluge, H; König, B; Lorkowski, S; Schutkowski, A; Schwerdtle, T; Stangl, GI | 1 |
| Al Refaii, A; Barraud, P; Brachet, F; Caillet, J; Dégut, C; Droogmans, L; Feller, A; Larue, V; Roovers, M; Tisné, C | 1 |
| Chen, S; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, J; Wang, Z | 1 |
| Baltissen, MP; Ignatova, VV; Jansen, PWTC; Schneider, R; Vermeulen, M | 1 |
| Booker, SJ; Laremore, TN; Miller, DV; Radle, MI | 1 |
| Blei, F; Fricke, J; Hoffmeister, D; Kargbo, R; Naschberger, A; Orry, A; Rupp, B; Sherwood, A | 1 |
| Gu, B; Song, Y; Tan, X; Yang, L; Zhou, T; Zong, Y | 1 |
| Almarei, M; Bauerle, MR; Boal, AK; Booker, SJ; Corrigan, PS; Gumkowski, JD; Krebs, C; Martinie, RJ; Pan, J; Silakov, A | 1 |
| Bröhm, A; Elsawy, H; Jeltsch, A; Kudithipudi, S; Rathert, P; Schoch, T; Schuhmacher, MK; Weirich, S | 1 |
| Araki, K; Araki, M; Kitagawa, S; Nakagawa, S; Shinoda, S; Suzuki, T; Tomizawa, K; Wei, FY | 1 |
| Jin, WB; Tang, GL; Wu, S; Xu, YF; Yuan, H | 1 |
| Dreumont, N; Leheup, B; Mosca, P | 1 |
| Blaszczyk, AJ; Booker, SJ; Knox, HL | 1 |
| Shelton, SB; Xhemalce, B | 1 |
| An, JH; Goo, E; Hwang, I; Jeong, H; Kang, Y; Kim, H | 1 |
| Chen, C; Han, X; Jia, L; Ma, Y; Taj, A; Wang, C; Yan, Q; Zhao, L | 1 |
| Chen, S; Chi, Z; Jiang, D; Li, W; Wang, D; Wang, Z; Wu, Y; Xu, T; Yang, X; Yu, W; Zhang, K; Zhang, X | 1 |
| Martin, NI; van Haren, MJ; Zhang, Y | 1 |
| Hirata, A; Hori, H; Okada, K; Saijo, S; Shimizu, N; Shiraishi, H; Yonezawa, K; Yoshii, K | 1 |
| Hevel, JM; Price, OM | 1 |
| Brown, JI; Frankel, A; Page, BDG | 1 |
| Bhaskar, B; Carraway, KR; Mansfield, KD; Misra, S; Nance, DJ; Satterwhite, ER | 1 |
| Frankel, A | 1 |
| Bulko, I; Dmytrenko, I; Korda, M; Nechyporuk, V; Pentiuk, L | 1 |
| Cai, H; Gao, Y; Gu, H; Gu, J; Li, A; Li, J; Lu, M; Lu, Y; Ma, Y; Zhou, J | 1 |
| Han, Q; Hoffman, RM | 1 |
| Ahmed-Belkacem, R; Canard, B; Debart, F; Decroly, E; Guiraud, M; Sutto-Ortiz, P; Vasseur, JJ | 1 |
| Elder, K; Ménézo, Y | 1 |
| Atdjian, C; Braud, E; Coelho, D; Ethève-Quelquejeu, M; Iannazzo, L | 1 |
| Bachhawat, AK; Bhatia, M; Chakraborty, R; Laxman, S; Masakapalli, SK; Oniel, R; Pradhan, S; Sengupta, S; Sharma, M; Suyal, S; Thakur, J | 1 |
| Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Kožich, V; Stabler, S | 1 |
| Elango, R | 1 |
| Ghaem Maghami, M; Höbartner, C; Lenz, AK; Scheitl, CPM | 1 |
| Gupta, R; Kadamur, G; Laxman, S; Sreedharan, S; Srinivasan, R; Walvekar, AS | 1 |
| Li, MO; Shyu, A; Xu, K | 1 |
| Blaszczyk, AJ; Booker, SJ; Chen, PY; Drennan, CL; Grove, TL; Knox, HL; Mukherjee, A; Schwalm, EL; Wang, B | 1 |
| Alhanti, B; Cheema, AK; Giczewska, A; Givertz, MM; Handy, DE; Joseph, J; Loscalzo, J; Mann, DL | 1 |
| Muthmann, N; Rentmeister, A; van Dülmen, M | 1 |
| Ali, ES; Asara, JM; Ben-Sahra, I; Gao, P; Helmin, KA; O'Hara, BP; Sahu, U; Singer, BD; Villa, E | 1 |
| Chen, C; Lan, C; Lan, L; Li, X; Lu, C; Meng, L; Mo, L; Tang, S; Wang, Q; Wang, X; Wu, B; Zeng, X; Zhang, N | 1 |
| Chen, KM; Delaney, K; Homolka, D; Mendel, M; Pandey, RR; Pillai, RS; Steiner, FA; Vågbø, CB; Wenda, JM | 1 |
| Hammerschmidt, F; McLaughlin, MI; Pallitsch, K; van der Donk, WA; Wallner, G | 1 |
| Rosen, BP; Rossman, TG; Yoshinaga-Sakurai, K | 1 |
| Chard, R; Foster, IT; Jedrzejczak, R; Joachimiak, A; Kim, Y; Lavens, A; Maltseva, N; Michalska, K; Minasov, G; Rosas-Lemus, M; Saint, N; Satchell, KJF; Sherrell, DA; Shuvalova, L; Wilamowski, M | 1 |
| Arya, S; Chan, SH; Dai, N; Gupta, YK; Martinez-Sobrido, L; Misra, A; Qi, S; Viswanathan, T | 1 |
| Brunzelle, JS; Daczkowski, CM; Hoover, P; Inniss, NL; Mesecar, AD; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Breuker, K; Flemmich, L; Heel, S; Micura, R; Moreno, S | 1 |
| Mansfield, KD; Satterwhite, ER | 1 |
| Alberto, JM; Coelho, D; Dreumont, N; Guéant, JL; Hergalant, S; Kundu, U; Leheup, B; Meyer, M; Mosca, P; Robert, A; Umoret, R | 1 |
| Jiang, M; Luo, M; Seneviranthe, C; Wang, K; Weiss, N | 1 |
| Chapple, BP; Classen, T; Henßen, B; Paschold, B; Pietruszka, J; Schatton, M; Schneider, P; Seebeck, FP | 1 |
| Denkhaus, L; Einsle, O; Fetzner, S; Gerhardt, S; Sartor, P | 1 |
| Bauer, C; Liao, C; Peng, J; Seebeck, FP | 1 |
| Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M | 1 |
| Baabe, D; Bröring, M; Burghaus, O; Gutsmann, T; Hurwitz, R; Kolbe, M; Nehls, C; Wang, C | 1 |
| Falkous, G; Freyer, C; Gorman, GS; Guha, N; Hopton, S; Lam, A; Lewis, D; Moedas, MF; Moore, D; Poulton, J; Pyle, A; Schober, FA; Sergeant, K; Smith, C; Tang, JX; Taylor, RW; Wredenberg, A; Zierz, CM | 1 |
| Benjdia, A; Bernardo-García, N; Berteau, O; Brewee, C; Chavas, LMG; Fradale, L; Fyfe, CD; Grimaldi, S; Guillot, A; Legrand, P | 1 |
| Boal, AK; Booker, SJ; Knox, HL; Sinner, EK; Townsend, CA | 1 |
| Li, M; Ling, H; Liu, C; Lu, L; Shen, Y; Sun, S; Wang, J; Xu, N; Yang, C; Zhang, J; Zhang, W; Zhang, X; Zhao, L | 1 |
| Lin, B; Liu, Q; Tao, Y | 1 |
| Benjdia, A; Berteau, O; Brewee, C; Guillot, A; Guinchard, X; Haumann, M; Kubiak, X; Sabat, N; Soualmia, F | 1 |
| Drennan, CL; Ulrich, EC | 1 |
| Fustin, JM | 1 |
| Fukumoto, K; Fustin, JM; Hayes, A; Ito, K; Okamura, H; Saer, B; Taylor, G; Toriba, Y; Yamano, M; Ye, S | 1 |
| Fang, W; Tong, X; Yang, S; Ye, C; Zhu, Y | 1 |
| Chun, SW; Lao, Y; Narayan, ARH; Skiba, MA; Smith, JL | 1 |
| Alam, M; Hashimoto, S; Igarashi, K; Inada, T; Ishii, Y; Kaneko, MK; Kato, Y; Liu, L; Long, NC; Matsumoto, M; Matsuo, Y; Nobuta, R; Sato, N; Shima, H; Sugiyama, T | 1 |
| Andexer, JN; Friedrich, T; Gagsteiger, J; Gericke, L; Heidinger, L; Jahn, S; Layer, G; Loenarz, C | 1 |
| Deng, WH; Liao, RZ | 1 |
| Idigo, NJ; Voigt, P | 1 |
| Bershtein, S; Diener, J; Huber, P; Niedermayer, C; Richter, M; Roth, S; Simon-Baram, H; Speck, M | 1 |
| Leisinger, F; Leopold, V; Seebeck, FP; Wen, X | 1 |
| Androsiuk, P; Bednarek, PT; Orłowska, R; Zebrowski, J; Zimny, J | 1 |
| Chen, J; Galván, AE; Rosen, BP; Viswanathan, T; Yoshinaga, M | 1 |
| Alarcón, CR; Perez-Pepe, M | 1 |
| Al-Jammal, WK; Barth, SA; Ellerhorst, M; Graça, AP; Lackner, G; Peña-Ortiz, L; Vilotijevic, I | 1 |
| Eguchi, T; Hamano, Y; Hashimoto, J; Kozone, I; Kudo, F; Maruyama, C; Minato, A; Nagano, N; Sato, S; Shin-Ya, K | 1 |
| Fogle, HM; Krupenko, NI; Krupenko, SA; McCormac, JP; Molina, S; Rushing, BR; Sharma, J; Sumner, S; You, M | 1 |
| Breger, K; Brown, JA | 1 |
| Babu, K; Nam, Y; Onolbaatar, O; Raj, R; Roberts, PH; Ruiz-Arroyo, VM | 1 |
| Erba, P; Jarecki, SA; Lashley, A; Miller, R; Provenzano, S; Salim, V | 1 |
| Bobileva, O; Bobrovs, R; Bula, AL; Grinberga, S; Jaudzems, K; Jirgensons, A; Kanepe, I; Patetko, L; Ramata-Stunda, A; Sirma, EE | 1 |
| Fan, PH; Lee, YH; Liu, HW; Ruszczycky, MW; Yeh, YC; Zhong, A | 1 |
| Andexer, JN; Cornelissen, NV; Gagsteiger, J; Gericke, L; Jahn, S; Jessen, HJ; Karst, LC; Kuge, M; Layer, G; Loenarz, C; Mhaindarkar, D; Mohr, MKF; Mordhorst, S; Rentmeister, A; Seebeck, FP; Wen, X | 1 |
| Cornelissen, NV; Hammer, SC; Hoffmann, A; Rentmeister, A; Schülke, KH | 1 |
| Francis, JW; Gozani, O; Lu, J; Narkhede, P; Shao, Z; Song, J; Trinh, AT | 1 |
| Guo, Y; Lu, Y; Pasin, F; San León, D; Sun, Z; Yue, J; Zhao, M | 1 |
| Bartosik, K; Braud, E; Coelho, D; Ethève-Quelquejeu, M; Iannazzo, L; Le Corre, L | 1 |
| Parker, HV; Schaner Tooley, CE; Tooley, JG | 1 |
| Conrad, NK; Flaherty, JN; Hunter, OV; Ruiz, JC | 1 |
| Fujishiro, H; Nakamura, Y; Okamoto, Y; Sumi, D; Taguchi, H | 1 |
| Dobreva, G; Duman, MB; Mathes, A; Neumann, A; Schmidt, T | 1 |
| Perez, MF; Sarkies, P | 1 |
| Bollu, A; Cornelissen, NV; Dieterich, C; Hartstock, K; Hüwel, S; Kueck, NA; Ovcharenko, A; Rentmeister, A; Spacek, P | 1 |
| Dhakal, D; Lee, JC; Poudel, PB; Sohng, JK | 1 |
| Dong, M; Wang, W | 1 |
113 review(s) available for isomethyleugenol and s-adenosylmethionine
| Article | Year |
|---|---|
Formation and metabolism of alkylated nucleosides: possible role in carcinogenesis by nitroso compounds and alkylating agents.
Topics: Alkylating Agents; Animals; Base Sequence; Carcinogens; DNA; DNA Restriction Enzymes; Ethionine; Methylation; Mutation; Nitroso Compounds; Nucleosides; Protein Biosynthesis; RNA; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; tRNA Methyltransferases | 1977 |
Mechanisms for the biomethylation of metals and metalloids.
Topics: Alkylmercury Compounds; Arsenic; Carbazoles; Cell Membrane Permeability; Metals; Methylation; Methylmercury Compounds; Organometallic Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyrenes; S-Adenosylmethionine; Spectrometry, Fluorescence; Tetrahydrofolates; Vitamin B 12 | 1978 |
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
Restriction endonucleases.
Topics: Base Sequence; Chemical Phenomena; Chemistry; Coliphages; DNA Restriction Enzymes; DNA, Bacterial; DNA, Viral; Electrophoresis, Agar Gel; Enzyme Activation; Escherichia coli; Genes, Viral; Methylation; Nucleic Acid Conformation; Plasmids; Protein Biosynthesis; S-Adenosylmethionine | 1978 |
A review of recent studies of the biosynthesis and excretion of hallucinogens formed by methylation of neurotransmitters or related substances.
Topics: Alcohol Oxidoreductases; Bufotenin; Carbolines; Dimethoxyphenylethylamine; Dopamine; Ethylamines; Folic Acid; Hallucinogens; Humans; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Norepinephrine; S-Adenosylmethionine; Schizophrenia; Serotonin; Tryptamines | 1976 |
Ascorbic acid and catecholamines.
Topics: Animals; Ascorbic Acid; Catechol O-Methyltransferase; Catecholamines; Epinephrine; Guinea Pigs; Humans; Liver; Methylation; Rats; S-Adenosylmethionine; Species Specificity | 1976 |
The methylation of tRNA.
Topics: Animals; Base Sequence; Binding Sites; Cations, Monovalent; Cell Differentiation; Embryo, Mammalian; Escherichia coli; Gonadal Steroid Hormones; Humans; Methylation; Neoplasms; Nucleic Acid Conformation; Nucleosides; Polyamines; RNA, Transfer; S-Adenosylmethionine; Species Specificity; Structure-Activity Relationship; tRNA Methyltransferases | 1976 |
Biological methylation: selected aspects.
Topics: Amino Acids; Bacteria; Carbohydrate Metabolism; Fungi; Methylation; Polysaccharides; Proteins; S-Adenosylmethionine; Tetrahydrofolates | 1975 |
The formation of internal 6-methyladenine residues in eucaryotic messenger RNA.
Topics: Adenine; Animals; Eukaryotic Cells; Humans; Methylation; RNA, Messenger; S-Adenosylmethionine | 1992 |
[The importance of methylation reactions in the biochemistry of catecholaminergic and serotoninergic neurons].
Topics: Animals; Brain; Depression; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Methylation; Rats; S-Adenosylmethionine; Serotonin; Sodium | 1991 |
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine | 1992 |
Biochemistry and pharmacology of S-adenosyl-L-methionine and rationale for its use in liver disease.
Topics: Animals; Cell Membrane; Depressive Disorder; Humans; Liver Diseases; Methylation; S-Adenosylmethionine | 1990 |
Physiological methylation in carcinogenesis.
Topics: Animals; Choline Deficiency; DNA; Humans; Liver Neoplasms; Methionine; Methylation; Oxidation-Reduction; S-Adenosylmethionine | 1990 |
Neuropharmacology of S-adenosyl methionine.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Folic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Methionine Adenosyltransferase; Methylation; Nervous System Diseases; Phospholipids; Proteins; Rats; S-Adenosylmethionine; Schizophrenia; Synapses; Synaptic Transmission | 1986 |
Protein carboxyl methylation in eukaryotes.
Topics: Amino Acid Sequence; Animals; Fungal Proteins; Mating Factor; Methylation; Peptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein O-Methyltransferase; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); S-Adenosylmethionine; Substrate Specificity | 1989 |
Models of aldosterone action on sodium transport: emerging concepts.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphate; Aldosterone; Amiloride; Amphotericin B; Animals; Biological Transport, Active; Bufonidae; Cell Membrane Permeability; Citric Acid Cycle; Kidney; Kidney Tubules, Collecting; Methylation; Mice; Models, Biological; Molecular Weight; Potassium; Quinacrine; Rats; S-Adenosylmethionine; Sodium; Sodium-Potassium-Exchanging ATPase; Trypsin; Urinary Bladder; Vasopressins | 1986 |
[Interaction of the cyclase and transmethylase systems].
Topics: Adenosylhomocysteinase; Adenylyl Cyclases; Calcium; Cyclic AMP; Drug Interactions; Hydrolases; Membrane Proteins; Methylation; Protein Binding; Receptors, Cell Surface; S-Adenosylmethionine; Substrate Specificity | 1986 |
Methyl group metabolism in sheep.
Topics: Adaptation, Physiological; Animal Nutritional Physiological Phenomena; Animals; Methylation; S-Adenosylmethionine; Sheep | 1987 |
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
Protein O-carboxylmethylation in relation to male gamete production and function.
Topics: Animals; Cell Differentiation; Humans; Male; Methylation; Protein Biosynthesis; Protein O-Methyltransferase; Proteins; Rats; S-Adenosylmethionine; Sperm Maturation; Sperm Motility; Sperm Transport; Spermatozoa; Testis | 1985 |
[Protein carboxymethylation and its role in the regulation of neurosecretion].
Topics: Adenosine Triphosphate; Endocrine Glands; Hormones; Humans; Methylation; Neurosecretory Systems; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
[Current data on the lateral biochemical effects of dopa].
Topics: Aminobutyrates; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopa Decarboxylase; Melatonin; Metabolism; Methylation; Polyribosomes; Protein Biosynthesis; Pyridoxal Phosphate; S-Adenosylmethionine; Stimulation, Chemical; Tryptophan; Tyrosine 3-Monooxygenase | 1974 |
The tRNA methyltransferases.
Topics: Animals; Bacteriophages; Base Sequence; Binding Sites; Biological Evolution; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Escherichia coli; Genetics, Microbial; Methylation; Methyltransferases; Mice; Mutation; Nucleic Acid Conformation; Organ Specificity; Rats; RNA, Transfer; S-Adenosylmethionine; Virus Replication; Viruses | 1972 |
[S-adenosylmethionine and its biochemical functions].
Topics: Adenosine Triphosphate; Binding Sites; Biochemical Phenomena; Biochemistry; Chemical Phenomena; Chemistry, Organic; Chemistry, Physical; Methylation; Models, Chemical; Organic Chemistry Phenomena; S-Adenosylmethionine; Spectrophotometry; Structure-Activity Relationship | 1972 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Phospholipid methylation and biological signal transmission.
Topics: Adrenal Medulla; Animals; Arachidonic Acids; Calcium; Cell Membrane; Chemotaxis, Leukocyte; Histamine Release; Lymphocyte Activation; Membrane Fluidity; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Receptors, Adrenergic, beta; Receptors, Drug; S-Adenosylmethionine | 1980 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Chemotaxis and methylation in a macrophage cell line.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1983 |
Toxicity-induced aberrant methylation of DNA and its repair.
Topics: Alkylation; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; DNA; DNA Repair; Formaldehyde; Guanine; Hydrazines; Methylation; Methylhydrazines; S-Adenosylmethionine | 1984 |
S-adenosylmethionine levels in psychiatric and neurological disorders: a review.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; AIDS Dementia Complex; Alzheimer Disease; Brain; Catecholamines; Child; Child, Preschool; Depressive Disorder; DNA; Female; Humans; Injections, Intravenous; Liver; Male; Metabolic Diseases; Methylation; Middle Aged; Nervous System Diseases; Phospholipids; RNA; S-Adenosylmethionine; Spinal Cord Diseases | 1994 |
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases | 1994 |
Enzymatic formation of N2,N2-dimethylguanosine in eukaryotic tRNA: importance of the tRNA architecture.
Topics: Guanosine; Methylation; Molecular Structure; Nucleic Acid Conformation; RNA Processing, Post-Transcriptional; RNA, Fungal; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases; Yeasts | 1995 |
Structure and function of DNA methyltransferases.
Topics: Adenine; Amino Acid Sequence; Binding Sites; Catechol O-Methyltransferase; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Methylation; Methyltransferases; Molecular Sequence Data; Protein Conformation; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1995 |
Effects of antagonists of polyamine metabolism on African trypanosomes.
Topics: Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Eflornithine; Methylation; Polyamines; S-Adenosylmethionine; Trypanosoma; Trypanosomiasis, African | 1993 |
Effects of arginine, S-adenosylmethionine and polyamines on nerve regeneration.
Topics: Arginine; Humans; Methylation; Nerve Regeneration; Nerve Tissue; Nerve Tissue Proteins; Polyamines; S-Adenosylmethionine | 1994 |
Binding site revealed of nature's most beautiful cofactor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Escherichia coli; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1994 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
Protein methylation.
Topics: Aging; Amino Acid Sequence; Amino Acids; Animals; Eukaryotic Cells; Methylation; Molecular Sequence Data; Prokaryotic Cells; Protein Methyltransferases; Protein Processing, Post-Translational; Proteins; S-Adenosylmethionine | 1993 |
Folate, alcohol, methionine, and colon cancer risk: is there a unifying theme?
Topics: Alcohol Drinking; Animals; Colonic Neoplasms; DNA; Ethanol; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Risk Factors; S-Adenosylmethionine | 1994 |
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: is DNA methylation involved?
Topics: Animals; Anticarcinogenic Agents; DNA; Gene Expression; Genes, myc; Genes, ras; Liver Neoplasms, Experimental; Methylation; Rats; S-Adenosylmethionine | 1993 |
Prevention of DNA 5-methylcytosine reutilization in human cells.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; DNA; Gene Expression Regulation; Homeostasis; Humans; Methylation; Models, Biological; Plants; S-Adenosylmethionine; Transcription, Genetic | 1995 |
S-Adenosylmethionine and methylation.
Topics: Adenosylhomocysteinase; Animals; DNA; Humans; Hydrolases; Methylation; Phospholipids; Proteins; RNA; S-Adenosylmethionine | 1996 |
Metabolic interference of melanogenesis in pigment cells.
Topics: Animals; Catechol O-Methyltransferase; DNA; Humans; Melanins; Melanocytes; Methylation; S-Adenosylmethionine | 1996 |
"Small is beautiful": major modifications in DNA structure or dynamics by small substituents or ligands.
Topics: Adenine; Base Sequence; Deoxyribose; DNA; Guanine Nucleotides; Guanosine; Ligands; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Polydeoxyribonucleotides; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1996 |
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia | 1997 |
S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation, Enzymologic; Humans; Liver; Liver Diseases; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Species Specificity | 1997 |
The metabolism of homocysteine: pathways and regulation.
Topics: Animals; Homocysteine; Humans; Hydrolysis; Methionine; Methylation; S-Adenosylmethionine | 1998 |
Demyelination and inborn errors of the single carbon transfer pathway.
Topics: Demyelinating Diseases; Humans; Liver; Metabolism, Inborn Errors; Methionine Adenosyltransferase; Methylation; Myelin Basic Protein; One-Carbon Group Transferases; S-Adenosylmethionine | 1998 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Sulfur metabolism in Escherichia coli and related bacteria: facts and fiction.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Biological Transport, Active; Cysteine; Escherichia coli; Genes, Bacterial; Methionine; Methylation; Molecular Sequence Data; Oxidation-Reduction; S-Adenosylmethionine; Selenium; Sulfonic Acids; Sulfur | 2000 |
1-Methyladenine: a starfish oocyte maturation-inducing substance.
Topics: Adenine; Adenosine Triphosphate; Animals; Cell-Free System; DNA, Complementary; Evolution, Molecular; Female; GTP-Binding Proteins; Hormones; Invertebrate Hormones; Meiosis; Methylation; Neuropeptides; Oocytes; Oogenesis; Ovarian Follicle; Phylogeny; Receptors, Neuropeptide; S-Adenosylmethionine; Signal Transduction; Starfish | 2000 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
S-Adenosyl-L-methionine (SAMe): from the bench to the bedside--molecular basis of a pleiotrophic molecule.
Topics: Animals; Depression; Diffusion of Innovation; Humans; Liver Diseases; Methylation; Nervous System Diseases; Osteoarthritis; S-Adenosylmethionine; Tissue Distribution | 2002 |
Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism.
Topics: Biomarkers; Carbon; Diet; DNA Methylation; Folic Acid; Homocysteine; Humans; Methylation; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2003 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Methylation demand and homocysteine metabolism.
Topics: Animals; Homocysteine; Humans; Levodopa; Methionine Adenosyltransferase; Methylation; Methyltransferases; Niacin; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2004 |
Autotoxicity, methylation and a road to the prevention of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine Agents; Humans; Methylation; Niacinamide; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; S-Adenosylmethionine | 2005 |
S-adenosylmethionine and protein methylation.
Topics: Animals; Humans; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylmethionine | 2005 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Amino acids and the regulation of methyl balance in humans.
Topics: Amino Acids; Animals; Creatine; Epigenesis, Genetic; Humans; Liver Diseases; Methionine; Methylation; Mice; Mutation; Neural Tube Defects; Polymorphism, Genetic; S-Adenosylmethionine | 2007 |
S-adenosylmethionine and its products.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glycine N-Methyltransferase; Homocysteine; Humans; Liver; Methionine Adenosyltransferase; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteine.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 2007 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Anaerobic functionalization of unactivated C-H bonds.
Topics: Alkanes; Enzymes; Methylation; Oxygen; S-Adenosylmethionine; Sulfur | 2009 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Glycine N-methyltransferase and regulation of S-adenosylmethionine levels.
Topics: Animals; Gene Expression Regulation, Enzymologic; Glycine N-Methyltransferase; Humans; Methylation; Models, Biological; Protein Structure, Secondary; S-Adenosylmethionine | 2009 |
The logic of the hepatic methionine metabolic cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Glycine N-Methyltransferase; Humans; Liver; Metabolic Networks and Pathways; Methionine; Methionine Adenosyltransferase; Methylation; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2010 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms.
Topics: Arsenic; Gene Frequency; Humans; Methylation; Methyltransferases; Polymorphism, Single Nucleotide; Racial Groups; S-Adenosylmethionine | 2011 |
S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?
Topics: Adenosine; Alkylation; Cyclopropanes; Cytosine; DNA; Histidine; Methylation; Methyltransferases; Nucleosides; RNA; RNA, Ribosomal, 23S; S-Adenosylmethionine | 2011 |
Complex biotransformations catalyzed by radical S-adenosylmethionine enzymes.
Topics: Biochemistry; Biotransformation; Catalysis; Escherichia coli; Free Radicals; Guanosine Triphosphate; Methylation; Models, Chemical; Molybdenum; Ribosomes; S-Adenosylmethionine; Software | 2011 |
Radical-mediated enzymatic methylation: a tale of two SAMS.
Topics: Free Radicals; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2012 |
Autoimmune diseases and polyamines.
Topics: Animals; Autoimmune Diseases; Epigenomics; Humans; Methylation; Polyamines; S-Adenosylmethionine | 2012 |
Resurgence of serine: an often neglected but indispensable amino Acid.
Topics: Animals; Brain; Humans; Methylation; Phosphoenolpyruvate Carboxykinase (ATP); Phosphoenolpyruvate Carboxykinase (GTP); Phosphoglycerate Dehydrogenase; S-Adenosylmethionine; Serine | 2012 |
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; Methyltransferases; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Tumor Necrosis Factor-alpha | 2013 |
Radical SAM enzymes in methylation and methylthiolation.
Topics: Methylation; Models, Molecular; Protein Methyltransferases; S-Adenosylmethionine; Stereoisomerism | 2012 |
S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system.
Topics: Adenosylhomocysteinase; Animals; Humans; Methylation; Models, Biological; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
Radical SAM-mediated methylation reactions.
Topics: Free Radicals; Methylation; RNA; S-Adenosylmethionine; Substrate Specificity; Tryptophan | 2013 |
Recent advances in radical SAM enzymology: new structures and mechanisms.
Topics: Amino Acid Motifs; Archaeal Proteins; Binding Sites; DNA Repair; Enzymes; Escherichia coli Proteins; Iron-Sulfur Proteins; Methylation; Methyltransferases; Proteins; S-Adenosylmethionine; Sulfurtransferases | 2014 |
SPASM and twitch domains in S-adenosylmethionine (SAM) radical enzymes.
Topics: Animals; Coenzymes; Free Radicals; Humans; Iron-Sulfur Proteins; Metalloproteins; Methylation; Molybdenum Cofactors; Protein Methyltransferases; Protein Structure, Tertiary; Pteridines; S-Adenosylmethionine; Sulfatases; Triose-Phosphate Isomerase | 2015 |
The biosynthesis of thiol- and thioether-containing cofactors and secondary metabolites catalyzed by radical S-adenosylmethionine enzymes.
Topics: Animals; Coenzymes; Free Radicals; Humans; Iron-Sulfur Proteins; Methylation; Protein Methyltransferases; S-Adenosylmethionine; Sulfhydryl Compounds; Sulfides | 2015 |
Radical S-adenosylmethionine (SAM) enzymes in cofactor biosynthesis: a treasure trove of complex organic radical rearrangement reactions.
Topics: Animals; Coenzymes; Free Radicals; Heme; Humans; Metalloproteins; Methylation; Molybdenum Cofactors; Protein Methyltransferases; Pteridines; S-Adenosylmethionine; Thiamine; Vitamin K 2 | 2015 |
Radical S-adenosyl-L-methionine chemistry in the synthesis of hydrogenase and nitrogenase metal cofactors.
Topics: Animals; Coenzymes; Free Radicals; Humans; Metals; Methylation; Protein Methyltransferases; S-Adenosylmethionine | 2015 |
Mechanistic diversity of radical S-adenosylmethionine (SAM)-dependent methylation.
Topics: Animals; Free Radicals; Humans; Methylation; Protein Methyltransferases; S-Adenosylmethionine | 2015 |
Introduction to the thematic minireview series on radical S-adenosylmethionine (SAM) enzymes.
Topics: Animals; Free Radicals; Humans; Methylation; Protein Methyltransferases; S-Adenosylmethionine | 2015 |
The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer.
Topics: Acetylation; Acetylglucosamine; Citric Acid Cycle; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glycosylation; Histones; Humans; Methylation; Neoplasms; S-Adenosylmethionine; Uridine Diphosphate | 2015 |
Iron-sulfur proteins responsible for RNA modifications.
Topics: Base Sequence; Humans; Iron-Sulfur Proteins; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 2015 |
RNA methyltransferases involved in 5' cap biosynthesis.
Topics: Animals; Humans; Methylation; Mice; Models, Molecular; RNA Caps; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Protozoan; RNA, Viral; S-Adenosylmethionine; tRNA Methyltransferases; Trypanosoma; Viruses | 2014 |
Creatine biosynthesis and transport in health and disease.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Animals; Biological Transport, Active; Brain Diseases, Metabolic, Inborn; Creatine; Developmental Disabilities; Energy Metabolism; Guanidinoacetate N-Methyltransferase; Gyrate Atrophy; Humans; Hyperammonemia; Intellectual Disability; Language Development Disorders; Mental Retardation, X-Linked; Methylation; Mitochondrial Membrane Transport Proteins; Movement Disorders; Mutation; Nerve Tissue Proteins; Ornithine; Plasma Membrane Neurotransmitter Transport Proteins; Prenatal Diagnosis; S-Adenosylmethionine; Speech Disorders; Urea Cycle Disorders, Inborn | 2015 |
One-carbon metabolism and epigenetics: understanding the specificity.
Topics: Animals; Chromatin; Epigenesis, Genetic; Epigenomics; Folic Acid; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; S-Adenosylmethionine; Substrate Specificity | 2016 |
S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders.
Topics: Animals; Depression; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Mental Disorders; Methylation; S-Adenosylmethionine; Time Factors | 2016 |
Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Methylation; Mice; Neoplasms; Peptide Synthases; Polyglutamic Acid; S-Adenosylmethionine; Signal Transduction | 2016 |
Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis.
Topics: Biological Products; Methylation; Methyltransferases; S-Adenosylmethionine | 2016 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Trans-methylation reactions in plants: focus on the activated methyl cycle.
Topics: Amino Acid Sequence; Arabidopsis; Methylation; Methyltransferases; Models, Biological; Plant Proteins; Plants; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; S-Adenosylmethionine; Signal Transduction | 2018 |
The molecular signature of muscle stem cells is driven by nutrient availability and innate cell metabolism.
Topics: Acetyl Coenzyme A; Acetylation; Chromatin; Diet; Epigenesis, Genetic; Histones; Humans; Ketoglutaric Acids; Methylation; Muscle, Skeletal; Nutritional Status; Protein Processing, Post-Translational; S-Adenosylmethionine; Stem Cells; Transcriptome | 2018 |
Crosstalk between metabolism and epigenetic modifications in autoimmune diseases: a comprehensive overview.
Topics: Acetyl Coenzyme A; Autoimmune Diseases; Chromatin; Epigenomics; Histones; Humans; Methylation; NAD; S-Adenosylmethionine; Sirtuins | 2018 |
Sink into the Epigenome: Histones as Repositories That Influence Cellular Metabolism.
Topics: Acetyl Coenzyme A; Acetylation; Animals; Epigenesis, Genetic; Histones; Humans; Methylation; S-Adenosylmethionine | 2018 |
Cobalamin-dependent radical S-adenosyl-l-methionine enzymes in natural product biosynthesis.
Topics: Adenine; Aminobutyrates; Biological Products; Enzymes; Fosfomycin; Gentamicins; Methylation; S-Adenosylmethionine; Shewanella; Thiostrepton; Vitamin B 12 | 2018 |
Mechanisms and Inhibitors of Histone Arginine Methylation.
Topics: Animals; Arginine; Enzyme Inhibitors; Histones; Humans; Methylation; Protein Isoforms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2018 |
Development of Chaetocin and S-Adenosylmethionine Analogues as Tools for Studying Protein Methylation.
Topics: Animals; Enzyme Inhibitors; Humans; Methylation; Piperazines; Protein Methyltransferases; Proteins; Proteomics; S-Adenosylmethionine | 2018 |
Refining and expanding nonribosomal peptide synthetase function and mechanism.
Topics: Bacteria; Biosynthetic Pathways; Carrier Proteins; Genome, Bacterial; Keto Acids; Methylation; Multigene Family; Oxidation-Reduction; Peptide Synthases; Peptides; S-Adenosylmethionine | 2019 |
Recent advances in HemN-like radical S-adenosyl-l-methionine enzyme-catalyzed reactions.
Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Duocarmycins; Enzymes; Escherichia coli Proteins; Heme; Hydrogen; Methylation; Peptides, Cyclic; Polyketides; Protein Methyltransferases; S-Adenosylmethionine; Thiazoles | 2020 |
Rapid and direct measurement of methyltransferase activity in about 30 min.
Topics: Catalysis; Enzyme Assays; Kinetics; Methylation; Protein-Arginine N-Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Tritium | 2020 |
Oral Methioninase for Covid-19 Methionine-restriction Therapy.
Topics: Administration, Oral; Antiviral Agents; Bacterial Proteins; Betacoronavirus; Carbon-Sulfur Lyases; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Humans; Lymphocyte Activation; Macrophage Activation; Meta-Analysis as Topic; Methionine; Methylation; Pandemics; Pneumonia, Viral; Pseudomonas putida; Recombinant Proteins; RNA Caps; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; T-Lymphocyte Subsets; Virus Replication | 2020 |
Epigenetic remodeling of chromatin in human ART: addressing deficiencies in culture media.
Topics: Amino Acids; Blastocyst; Chromatin; Chromatin Assembly and Disassembly; Congenital Abnormalities; Culture Media; DNA Methylation; DNA Repair; Embryo Culture Techniques; Embryonic Development; Endocrine Disruptors; Female; Genomic Imprinting; Glucose; Humans; Infant, Newborn; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oocytes; Oxidative Stress; Pregnancy; Reproductive Techniques, Assisted; S-Adenosylmethionine | 2020 |
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
RNA methyltransferase METTL16: Targets and function.
Topics: Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA, Long Noncoding; RNA, Messenger; S-Adenosylmethionine | 2022 |
Functional Diversification and Structural Origins of Plant Natural Product Methyltransferases.
Topics: Biological Products; Methylation; Methyltransferases; Plants; S-Adenosylmethionine; Substrate Specificity | 2022 |
[Synthesis and application of the methyl analogues of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine | 2023 |
5 trial(s) available for isomethyleugenol and s-adenosylmethionine
| Article | Year |
|---|---|
[Neuropsychiatric disorders and transmethylation: therapeutic effects of S-adenosyl-L-methionine].
Topics: Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Methylation; S-Adenosylmethionine | 1975 |
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Associations of methyl donor and methylation inhibitor levels during anti-oxidant therapy in heart failure.
Topics: Aged; Allopurinol; Female; Free Radical Scavengers; Heart Failure; Humans; Hyperuricemia; Male; Methylation; Middle Aged; Oxidation-Reduction; Precision Medicine; S-Adenosylhomocysteine; S-Adenosylmethionine; Stroke Volume; Treatment Outcome; Uric Acid; Xanthine Oxidase | 2021 |
1174 other study(ies) available for isomethyleugenol and s-adenosylmethionine
| Article | Year |
|---|---|
Non-enzymatic methylation of proteins with S-adenosyl-L-methionine.
Topics: Egg White; Globulins; Hydrogen-Ion Concentration; Methylation; Proteins; S-Adenosylmethionine; Structure-Activity Relationship; Thermodynamics | 1975 |
On the development and utilization of assays for biological transmethylation involving S-adenosylmethionine.
Topics: Animals; Brain; Humans; Mental Disorders; Methylation; Methyltransferases; Neurotransmitter Agents; S-Adenosylmethionine | 1978 |
Enzymatic S-methylation of 6-n-propyl-2-thiouracil and other antithyroid drugs.
Topics: Animals; Antithyroid Agents; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Male; Methimazole; Methylation; Methyltransferases; Mice; Peroxidases; Propylthiouracil; S-Adenosylmethionine; Sulfhydryl Compounds; Swine; Thiouracil; Thyroid Gland | 1975 |
Metabolism of 5-S-cyteinyldopa by O-methylation.
Topics: Animals; Cysteinyldopa; Dihydroxyphenylalanine; Guinea Pigs; Liver; Liver Extracts; Methylation; Rats; S-Adenosylmethionine | 1977 |
On lowering S-adenosylmethionine.
Topics: Animals; Levodopa; Liver; Methylation; Methyltransferases; Niacinamide; Norepinephrine; Rats; S-Adenosylmethionine | 1978 |
Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes.
Topics: Calcium; Calcium-Transporting ATPases; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Lipids; Methylation; Phospholipids; S-Adenosylmethionine | 1979 |
A blocked structure at the 5' terminus of mRNA from cytoplasmic polyhedrosis virus.
Topics: Adenine Nucleotides; Base Sequence; Electrophoresis, Paper; Guanine Nucleotides; Hydrolysis; Insect Viruses; Methylation; Oligonucleotides; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine | 1975 |
Methylated nucleotides block 5'-terminus of vaccinia virus messenger RNA.
Topics: Adenosine; Alkaline Phosphatase; Base Sequence; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Diphosphates; Electrophoresis; Guanosine; Methylation; Phosphorus Radioisotopes; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Tritium; Vaccinia virus | 1975 |
The 5' terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus.
Topics: Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Paper; Diphosphates; DNA-Directed RNA Polymerases; Electrophoresis, Paper; Guanosine; Guanosine Triphosphate; Methylation; Oligonucleotides; Phosphoric Diester Hydrolases; Pyrophosphatases; Ribonucleases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1975 |
Studies on steroid conjugates. XIV. Participation of glucuronidation in selective O-methylation of catechol estrogen in the rat.
Topics: Animals; Bile; Estrogens; Estrogens, Conjugated (USP); Glucuronates; Liver; Male; Methylation; Rats; S-Adenosylmethionine | 1975 |
5'-terminal sequence of vesicular stomatitis virus mRNA's synthesized in vitro.
Topics: Base Sequence; Cell-Free System; Chromatography, DEAE-Cellulose; Cytosine; DNA-Directed RNA Polymerases; Methylation; Nucleotides; Ribonucleases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1975 |
Characterization and translation of methylated and unmethylated vesicular stomatitis virus mRNA synthesized in vitro by ribonucleoprotein particles from vesicular stomatitis virus-infected L cells.
Topics: Base Sequence; Cell-Free System; Methylation; Peptide Biosynthesis; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus; Viral Proteins | 1976 |
Differential synthesis of blocked and unblocked 5'-termini in reovirus mRNA: effect of pyrophosphate and pyrophosphatase.
Topics: Diphosphates; Guanine Nucleotides; Mammalian orthoreovirus 3; Methylation; Pyrophosphatases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Transcription, Genetic | 1976 |
Two methyltransferase activities in the purified virions of vesicular stomatitis virus.
Topics: Kinetics; Methylation; Methyltransferases; Protein Biosynthesis; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus; Virion | 1977 |
Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes.
Topics: Animals; Erythrocyte Membrane; Erythrocytes; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; S-Adenosylmethionine | 1979 |
Phospholipid methylation stimulates lactogenic binding in mouse mammary gland membranes.
Topics: Animals; Binding Sites; Female; Growth Hormone; Kinetics; Lactation; Mammary Glands, Animal; Membrane Lipids; Methylation; Mice; Phospholipids; Pregnancy; Receptors, Cell Surface; S-Adenosylmethionine | 1979 |
Protein and phospholipid methylation during chemotaxis in Dictyostelium discoideum and its relationship to calcium movements.
Topics: Calcium; Chemoreceptor Cells; Chemotaxis; Cyclic AMP; Dictyostelium; Fungal Proteins; Membrane Lipids; Methylation; Molecular Weight; Phospholipids; S-Adenosylmethionine | 1979 |
Stereochemical studies of enzymic C-methylations.
Topics: Enzymes; Magnetic Resonance Spectroscopy; Methionine; Methylation; S-Adenosylmethionine; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12 | 1977 |
Requirement of S-adenosyl-L-methionine-mediated methylation for human monocyte chemotaxis.
Topics: Adenosine Deaminase Inhibitors; Blood Proteins; Chemotaxis, Leukocyte; Humans; Methylation; Monocytes; Phagocytosis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1978 |
Displacement and aberrant methylation in vitro of H-1 histone in rat liver nuclei after half-saturation of chromatin with polycations.
Topics: Animals; Cations; Cell Nucleus; Chromatin; Histones; Lysine; Methylation; Methyltransferases; Polylysine; Protamines; Rats; S-Adenosylmethionine; Spermidine | 1978 |
Evidence that xylosyladenine affects methylation by inhibition of S-adenosyl-L-methionine synthesis.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Nucleus; Coformycin; Deoxyadenosines; In Vitro Techniques; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; S-Adenosylmethionine; Xylose | 1979 |
[Some peculiarities of phage DDVI-specific methylases].
Topics: Adenine Nucleotides; Coliphages; DNA, Viral; Drug Stability; Enzyme Repression; Escherichia coli; Guanine; Methylation; Methyltransferases; Purines; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
[Specificity of the chemical methylation reaction of transfer RNA by means of dimethylsulfate. I].
Topics: Animals; Escherichia coli; Liver; Methane; Methylation; Rats; S-Adenosylmethionine; Sulfuric Acids; tRNA Methyltransferases; Yeasts | 1978 |
"Pretranscriptional capping" in the biosynthesis of cytoplasmic polyhedrosis virus mRNA.
Topics: Adenylyl Imidodiphosphate; Base Sequence; Guanine Nucleotides; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic | 1978 |
S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Stimulation, Chemical | 1978 |
ATP-induced conformational changes in the restriction endonuclease from Escherichia coli K-12.
Topics: Adenosine Triphosphate; Binding Sites; Coliphages; DNA Restriction Enzymes; DNA, Viral; Escherichia coli; Methylation; Protein Conformation; S-Adenosylmethionine; Substrate Specificity | 1978 |
Methylation-dependent DNA synthesis in Escherichia coli mediated by DNA polymerase I.
Topics: Adenosine Triphosphate; Chloramphenicol; Deoxyribonucleotides; DNA; DNA Polymerase I; DNA-Directed DNA Polymerase; Escherichia coli; Ethionine; Methylation; S-Adenosylmethionine | 1979 |
On the mechanism of sensory transduction in bacterial chemotaxis.
Topics: Carrier Proteins; Chemotaxis; Escherichia coli; Flagella; Membrane Potentials; Membrane Proteins; Methylation; Monosaccharides; Movement; Receptors, Drug; S-Adenosylmethionine | 1979 |
Permeabilization of cells for studies on the biochemistry of bacterial chemotaxis.
Topics: Animals; Aspartic Acid; Bacterial Proteins; Behavior, Animal; Cell Membrane Permeability; Chemotaxis; Escherichia coli; Methylation; Molecular Weight; S-Adenosylmethionine; Salmonella typhimurium; Serine | 1979 |
Attractants and repellents influence methylation and demethylation of methyl-accepting chemotaxis proteins in an extract of Escherichia coli.
Topics: Bacterial Proteins; Cell-Free System; Chemoreceptor Cells; Chemotaxis; Escherichia coli; Kinetics; Methylation; S-Adenosylmethionine | 1979 |
[Fluorimetric assay of 3-o-methyldopamine and 4-0-methyldopamine in rat urine and o-methylation of dopamine].
Topics: Animals; Deoxyepinephrine; Dopamine; Levodopa; Male; Methylation; Rats; S-Adenosylmethionine; Spectrometry, Fluorescence | 1977 |
Methylation hypothesis.
Topics: Adult; Animals; Brain; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Liver; Lung; Male; Methionine; Methylation; Mice; Rabbits; Rats; S-Adenosylmethionine; Tryptamines | 1979 |
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Mammalian DNA methylation and a nuclear S-adenosyl L-methionine-dependent nuclease activity.
Topics: Animals; Cell Cycle; Cell Nucleus; Cells, Cultured; Coliphages; Cricetinae; Deoxyribonucleases; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Methylation; Methyltransferases; Nucleic Acid Conformation; Recombination, Genetic; S-Adenosylmethionine | 1979 |
Synthesis and translation of mRNA containing 5'-terminal 7-ethylguanosine cap.
Topics: DNA-Directed RNA Polymerases; Guanosine; Kinetics; Mammalian orthoreovirus 3; Methylation; Plants; Protein Biosynthesis; RNA Cap Analogs; RNA, Messenger; S-Adenosylmethionine; Transcription, Genetic; Triticum | 1979 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Conversion of phosphatidylethanolamine to phosphatidylcholine in rat brain by the methylation pathway.
Topics: Animals; Brain; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1979 |
[Methylation and degradation of chromatin DNA in isolated rat liver cell nuclei].
Topics: Animals; Cell Nucleus; Chromatin; DNA; Kinetics; Liver; Methylation; Molecular Weight; Rats; S-Adenosylmethionine | 1979 |
Stereoselective enzymatic O-methylation of tetrahydropapaveroline and tetrahydroxyberbine alkaloids.
Topics: Animals; Berberine Alkaloids; Catechol O-Methyltransferase Inhibitors; In Vitro Techniques; Liver; Methylation; Methyltransferases; Papaverine; Proteins; Rats; S-Adenosylmethionine; Stereoisomerism; Tetrahydropapaveroline | 1979 |
Post-translational modification of actins synthesized in vitro.
Topics: Acetyl Coenzyme A; Acetylation; Actins; Animals; Cell Line; Methionine; Methylation; Muscles; Protein Biosynthesis; S-Adenosylmethionine | 1979 |
Impairment of reovirus mRNA methylation in extracts of interferon-treated Ehrilich ascites tumor cells: further characteristics of the phenomenon.
Topics: Animals; Carcinoma, Ehrlich Tumor; Culture Techniques; Humans; Interferons; Methylation; Methyltransferases; Mice; Poly I-C; Reoviridae; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
The RNA of unfertilized sea urchin eggs is "capped".
Topics: Animals; Cell-Free System; Female; Methylation; Ovum; Protein Biosynthesis; RNA; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sea Urchins; Zygote | 1977 |
Estimation of the methylating capacity of the pineal gland. With special reference to indole metabolism.
Topics: Animals; Chromatography, Thin Layer; In Vitro Techniques; Indoles; Methylation; Pineal Gland; Rats; S-Adenosylmethionine | 1978 |
Methylated cap formation by enzymes bound to nuclear informofer particles.
Topics: Animals; Cell Nucleus; Guanosine Triphosphate; In Vitro Techniques; Liver; Methylation; Nucleic Acid Precursors; Nucleoproteins; Nucleotidyltransferases; Oligonucleotides; Rats; Ribonucleoproteins; RNA, Messenger; S-Adenosylmethionine | 1978 |
Effects of various S-adenosylmethionine preparations on histamine methylation in vitro and in vivo.
Topics: Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Methylation; Mice; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1978 |
Assessment of methylation in nonhistone chromosomal proteins.
Topics: Amino Acids; Chromosomal Proteins, Non-Histone; Kidney; Methylation; Protein Methyltransferases; S-Adenosylmethionine | 1978 |
Transmethylations and the central nervous system: introduction.
Topics: Brain; Humans; Methylation; S-Adenosylmethionine; Schizophrenia | 1978 |
Effects of exogenous L-dopa on the metabolism of methionine and S-adenosylmethionine in the brain.
Topics: Animals; Brain; Levodopa; Methionine; Methylation; Rats; S-Adenosylmethionine | 1978 |
S-adenosyl-L-methionine (SAMe) and biogenic amine methylation processes.
Topics: Animals; Biogenic Amines; Brain; Catecholamines; Humans; Methylation; S-Adenosylmethionine | 1978 |
SAMe and histamine.
Topics: Animals; Brain; Histamine; Methylation; S-Adenosylmethionine | 1978 |
S-adenosyl-L-methionine and GABA metabolism in the brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Methylation; S-Adenosylmethionine; Synapses | 1978 |
Effect of acute hyperammonemia on metabolism and cerebral energy state.
Topics: Ammonia; Animals; Brain; Dogs; Energy Metabolism; Female; Glutamates; Glycolysis; Methylation; Motor Cortex; S-Adenosylmethionine | 1978 |
Enzymatic methylation of phosphatidylethanolamine increases erythrocyte membrane fluidity.
Topics: Animals; Cytoplasm; Erythrocyte Membrane; Erythrocytes; Male; Membrane Fluidity; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Temperature | 1978 |
Autoregulation of phospholipid N-methylation by the membrane phosphatidylethanolamine content.
Topics: Animals; Cells, Cultured; Ethanolamines; Liver; Membrane Lipids; Methionine; Methylation; Methyltransferases; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1978 |
Methionine metabolism in BHK cells: preliminary characterization of the physiological effects of cycloleucine, an inhibitor of s-adenosylmethionine biosynthesis.
Topics: Amino Acids; Cell Cycle; Cell Division; Cell Line; Cycloleucine; DNA; Dose-Response Relationship, Drug; Methionine; Methylation; Protein Biosynthesis; RNA; S-Adenosylmethionine | 1978 |
Effect of methionine-loading on methyl group synthesis and activation in rat brain and liver.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Glycine Hydroxymethyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Rats; S-Adenosylmethionine | 1978 |
Biosynthesis of ribosylthymine in the transfer RNA of Streptococcus faecalis: a folate-dependent methylation not involving S-adenosylmethionine.
Topics: Enterococcus faecalis; Folic Acid; Formates; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Thymine | 1975 |
In vitro modification and restriction of phage phi-105c DNA with Bacillus subtilis N cell-free extract.
Topics: Adenosine Triphosphate; Bacillus subtilis; Cell-Free System; Coliphages; DNA, Viral; Endonucleases; Magnesium; Methylation; S-Adenosylmethionine | 1975 |
Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA.
Topics: Adenosine; Bacillus subtilis; Borohydrides; Coenzymes; Escherichia coli; Methionine; Methylation; Methylguanidine; Micrococcus; Ribonucleosides; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Tetrahydrofolates; Uridine | 1975 |
Inhibition of DNA methylation by S-adenosylethionine with the production of methyl-deficient DNA in regenerating rat liver.
Topics: Animals; Carcinogens; DNA; Ethionine; Liver; Liver Regeneration; Male; Methylation; Rats; S-Adenosylmethionine | 1977 |
Time dependence of ethionine-induced changes in rat liver transfer RNA methylation.
Topics: Adenine; Animals; Cytosine; Drug Interactions; Ethionine; Female; Guanine; Liver; Methylation; Rats; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases; Uracil | 1977 |
In vitro synthesis of RNA containing 5'-terminal structure 7nG(5')ppp(5')Apm... by purified wound tumor virus.
Topics: Base Sequence; Cell-Free System; Methylation; Nucleotides; Plant Tumors; Plant Viruses; RNA, Viral; S-Adenosylmethionine | 1977 |
Bacterial tumble regulator may be inactivated by methylation.
Topics: Bacterial Physiological Phenomena; Bacterial Proteins; Chemotaxis; Locomotion; Methylation; Models, Biological; S-Adenosylmethionine | 1977 |
Biomethylation of toxic elements in the environment.
Topics: Arsenic; Biotransformation; Chemical Phenomena; Chemistry; Iron; Lead; Mercury; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Tin; Vitamin B 12 | 1977 |
Methyl group analysis of virion-associated high-molecular-weight RNA synthesized in vitro by purified vaccinia virus.
Topics: Base Sequence; Cell-Free System; HeLa Cells; Methylation; Molecular Weight; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Uracil Nucleotides; Vaccinia virus | 1977 |
Methylation of reovirus oligonucleotides in vivo and in vitro.
Topics: Base Sequence; Guanine Nucleotides; Mammalian orthoreovirus 3; Methylation; Oligonucleotides; Reoviridae; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Uracil Nucleotides | 1977 |
Biosynthesis of reovirus-specified polypeptides. System-dependent effect of reovirus mRNA methylation on translation in vitro catalyzed by ascites tumor and wheat embryo cell-free extracts.
Topics: Cell Line; Cell-Free System; Guanine Nucleotides; Methylation; Protein Biosynthesis; Reoviridae; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Viral Proteins | 1977 |
Methylation of histamine in the gastric mucosa.
Topics: Animals; Cats; Cimetidine; Dogs; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Methylation; Pentagastrin; Prednisolone; Rats; S-Adenosylmethionine; Species Specificity; Swine | 1977 |
O-methylation and decarboxylation of alpha-methyldopa in brain and spinal cord: depletion of S-adenosylmethionine and accumulation of metabolites in catecholaminergic neurones.
Topics: Animals; Brain; Catecholamines; Decarboxylation; Depression, Chemical; Hydroxydopamines; Injections, Intraventricular; Male; Methylation; Methyldopa; Mice; Neurons; Rats; S-Adenosylmethionine; Spinal Cord | 1976 |
Mass spectrometric identification of N-monomethyltryptamine following incubation of tryptamine with brain protein and S-adenosylmethionine or 5-methytetrahydrofolic acid.
Topics: Animals; Brain; Lung; Mass Spectrometry; Methylation; Nerve Tissue Proteins; Proteins; Rabbits; Rats; S-Adenosylmethionine; Tetrahydrofolates; Tryptamines | 1976 |
[In vitro methylation of nuclear DNA from various organs of a rat: Tissue and age differences in acceptor ability of DNA].
Topics: Aging; Animals; Brain; Cell Nucleus; Culture Media; DNA; DNA (Cytosine-5-)-Methyltransferases; In Vitro Techniques; Kidney; Liver; Lung; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Spleen; Tritium | 1976 |
Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.
Topics: Animals; Base Sequence; Borohydrides; Carbon Radioisotopes; Cell-Free System; DNA-Directed RNA Polymerases; Enzyme Precursors; Genotype; Guanosine Triphosphate; Methylation; Mice; Phosphorus Radioisotopes; Protein Biosynthesis; Protein Precursors; Reoviridae; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Transcription, Genetic; Tritium; Viral Proteins | 1975 |
Tetrahydrofolic acid: an inhibitor of the methyltetrahydrofolic acid-mediated methylation of indolethylamines.
Topics: Adenosine; Animals; Binding, Competitive; Bufotenin; Ethylamines; Homocysteine; Indoles; Lung; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Serotonin; Tetrahydrofolates | 1975 |
Synthesis of RNA containing a methylated blocked 5' terminus by HeLa nuclear homogenates.
Topics: Cell Nucleus; Guanine Nucleotides; HeLa Cells; Methylation; Ribonucleases; RNA, Neoplasm; S-Adenosylmethionine | 1975 |
Methylation of TMV RNA.
Topics: Chromatography, Gel; Escherichia coli; Kinetics; Methylation; RNA, Transfer; RNA, Viral; S-Adenosylmethionine; Time Factors; Tobacco Mosaic Virus; tRNA Methyltransferases | 1975 |
Tubercidin and isopropylureidopurine--inhibitors of ribothymidine synthesis in vitro.
Topics: Adenosine; Carbon Radioisotopes; Escherichia coli; Kinetics; Methylation; Purines; Ribonucleosides; RNA, Transfer; S-Adenosylmethionine; Thymidine; Tubercidin | 1975 |
tRNAs undermethylation in a met-regulatory mutant of Saccharomyces cerevisiae.
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Haploidy; Methionine; Methylation; Mutation; Nucleotides; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Tritium; tRNA Methyltransferases | 1975 |
Biological functions of the bacteriophage T3 SAMase gene.
Topics: Coliphages; DNA Viruses; DNA, Viral; Escherichia coli; Genes; Lysogeny; Methylation; Mutation; S-Adenosylmethionine; Transferases; Virus Replication | 1975 |
Transfer ribonucleic acid methylase deficiency found in UGA supressor strains.
Topics: Cell-Free System; Genes, Recessive; Genetic Code; Methylation; Mutation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Salmonella typhimurium; Suppression, Genetic; tRNA Methyltransferases | 1975 |
5-methyltetrahydrofolic acid is not a methyl donor for biogenic amines: enzymatic formation of formaldehyde.
Topics: Animals; Brain; Carbon Radioisotopes; Chromatography, Thin Layer; Dopamine; Formaldehyde; In Vitro Techniques; Isoquinolines; Methane; Methylamines; Methylation; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1975 |
The elevation of cerebral histamine-N-and catechol-O-methyl transferase activities by L-methionine-dl-sulfoximine.
Topics: Animals; Basal Ganglia; Brain; Brain Stem; Catechol O-Methyltransferase; Cerebellum; Cerebral Cortex; Guinea Pigs; Hippocampus; Histamine N-Methyltransferase; Hypothalamus; Kinetics; Male; Mesencephalon; Methionine; Methionine Sulfoximine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Depletion of S-adenosyl-L-methionine in mouse brain by antidepressive drugs.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain Chemistry; Cycloleucine; Depression, Chemical; Histamine N-Methyltransferase; Imipramine; Male; Methylation; Mice; Norepinephrine; S-Adenosylmethionine | 1975 |
Tissue-specific biosynthesis of epsilon-N-monomethyllysine and epsilon-N-trimethyllysine in skeletal and cardiac muscle myosin: a model for the cell-free study of post-translational amino acid modifications in proteins.
Topics: Animals; Chick Embryo; Chickens; Cytosol; Lysine; Methylation; Methyltransferases; Muscles; Myocardium; Myosins; Organ Specificity; Polyribosomes; Protein Biosynthesis; S-Adenosylmethionine | 1975 |
Methylating activity of (methyl-14C)-S-adenosylmethionine by microsomes of the insect Ceratitis capitata.
Topics: Animals; Diptera; Larva; Methylation; Microsomes; Phospholipids; S-Adenosylmethionine | 1975 |
Ribosome binding to reovirus mRNA in protein synthesis requires 5' terminal 7-methylguanosine.
Topics: Aurintricarboxylic Acid; Base Sequence; Binding Sites; Guanosine; Mammalian orthoreovirus 3; Methylation; Polyribosomes; Protein Biosynthesis; Reoviridae; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Subcellular Fractions; Triticum; tRNA Methyltransferases; Viral Proteins | 1975 |
The effect of ethionine on ribonucleic acid synthesis in rat liver.
Topics: Adenosine Triphosphate; Animals; Cycloheximide; Ethionine; Female; HeLa Cells; Inosine; Liver; Liver Neoplasms; Methionine; Methylation; Mitoguazone; Rats; RNA; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1975 |
A sensitive enzymatic assay for dextro- or levo-tranylcypromine in brain.
Topics: Amines; Animals; Brain Chemistry; In Vitro Techniques; Lung; Male; Methods; Methylation; Methyltransferases; Rabbits; Rats; S-Adenosylmethionine; Stereoisomerism; Tranylcypromine | 1975 |
Proceedings: Interaction with histamine metabolism by methyl derivatives of histamine and by commercial S-adenosymethionine.
Topics: Animals; Brain; Guinea Pigs; Histamine; Kidney; Methylation; Mice; Rats; S-Adenosylmethionine | 1975 |
Transfer of the methyl group of methionine to choline and to tRNA in the honeybee Apis mellifica L.
Topics: Animals; Bees; Choline; Cytosine; Fatty Acids; Guanine; Lipids; Methylation; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 1975 |
Synthesis of tetrahydro-beta-carbolines from indoleamines via enzymatic formation of formaldehyde from 5-methyltetrahydrofolic acid.
Topics: Animals; Brain; Carbolines; Chromatography, Thin Layer; Cysteine; Formaldehyde; In Vitro Techniques; Indoles; Lung; Methylation; Rabbits; Rats; S-Adenosylmethionine; Serotonin; Tetrahydrofolates; Tryptamines | 1975 |
Folate deficiency in the livers of diethylnitrosaminetreated rats.
Topics: Animals; Diethylnitrosamine; Folic Acid Deficiency; Glutamates; In Vitro Techniques; Liver; Male; Methionine; Methylation; Nitrosamines; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1976 |
Correlation of the ratio of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine in the brain and cerebrospinal fluid of the pig: implications for the determination of this methylation ratio in human brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Humans; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine | 1992 |
Localization of methyltransferase activities throughout the endomembrane system of flax (Linum usitatissimum L) hypocotyls.
Topics: Acid Anhydride Hydrolases; Adenosine Triphosphatases; Cell Fractionation; Chromatography, Gel; Endoplasmic Reticulum; Glucosyltransferases; Golgi Apparatus; Intracellular Membranes; Membrane Proteins; Methylation; Methyltransferases; Microsomes; NADH Dehydrogenase; Phosphoric Monoester Hydrolases; Plant Cells; Plants; S-Adenosylmethionine; Schizosaccharomyces pombe Proteins; Ultracentrifugation | 1992 |
Conferring new cleavage specificities of restriction endonucleases.
Topics: DNA; DNA Modification Methylases; DNA Restriction Enzymes; Genome; Hydrolysis; Indicators and Reagents; Methylation; Microspheres; S-Adenosylmethionine; Sepharose; Substrate Specificity | 1992 |
Purification and biochemical characterization of the EcaI DNA methyltransferase.
Topics: Adenosine; Base Sequence; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry, Physical; DNA; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; Plasmids; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Temperature | 1992 |
Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin, an indirect inhibitor of methylation?
Topics: Adenosine; Cell Nucleus; DNA; Genes, myc; Humans; Methylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Restriction Mapping; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1992 |
Properties of a partially purified phosphodimethylethanolamine methyltransferase from rat brain cytosol.
Topics: Ammonium Sulfate; Animals; Brain; Calcium; Cytosol; Ethanolamines; Fractional Precipitation; Hydrogen-Ion Concentration; Male; Methylation; Methyltransferases; Phosphorylcholine; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
Guanine nucleotides stimulate carboxyl methylation of kidney cytosolic proteins.
Topics: Animals; Cytosol; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Kidney Cortex; Kinetics; Male; Methylation; Organ Specificity; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Solubility | 1992 |
EcoRI DNA methyltransferase-DNA interactions.
Topics: Base Sequence; Deoxyribonuclease EcoRI; DNA; DNA Modification Methylases; Guanosine; Hot Temperature; Inosine; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; S-Adenosylmethionine; Substrate Specificity | 1992 |
Tissue distribution of enzymic methylation of glutathione S-transferase and its effects on catalytic activity. Methylation of glutathione S-transferase 11-11 inhibits conjugating activity towards 1-chloro-2,4-dinitrobenzene.
Topics: Analysis of Variance; Animals; Brain; Calmodulin; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cytosol; Dinitrochlorobenzene; Glutathione Transferase; Isoenzymes; Kidney; Liver; Lung; Macromolecular Substances; Male; Methylation; Molecular Weight; Myocardium; Organ Specificity; Rats; S-Adenosylmethionine; Testis | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Two gamma-subunits, gamma-I and gamma-II, complex with the same beta-subunits in bovine brain G-proteins (Gi/o).
Topics: Amino Acids; Animals; Brain; Cattle; Chromatography, Ion Exchange; DNA; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Macromolecular Substances; Methylation; Molecular Weight; Protein Binding; S-Adenosylmethionine; Tritium | 1992 |
Indole-N-methylated beta-carbolinium ions as potential brain-bioactivated neurotoxins.
Topics: Adenosine Diphosphate; Animals; Biotransformation; Brain; Carbolines; Corpus Striatum; Female; Methylation; Mitochondria; Molecular Structure; NAD; Oxygen Consumption; PC12 Cells; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1992 |
Methylation of FrzCD, a methyl-accepting taxis protein of Myxococcus xanthus, is correlated with factors affecting cell behavior.
Topics: Bacterial Proteins; Blotting, Western; Cell Movement; Chemotactic Factors; Genes, Bacterial; Genotype; Kinetics; Methylation; Models, Biological; Myxococcus xanthus; Phenotype; S-Adenosylmethionine; Signal Transduction; Tritium | 1992 |
Novel S-adenosylmethionine-dependent indole-N-methylation of beta-carbolines in brain particulate fractions.
Topics: Animals; Brain; Brain Chemistry; Carbolines; Cell Fractionation; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Indoles; Male; Methylation; S-Adenosylmethionine | 1992 |
Evidence of brain methyltransferase inhibition and early brain involvement in HIV-positive patients.
Topics: Adult; Brain; Female; HIV Seropositivity; Humans; Male; Methylation; Methyltransferases; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 1991 |
Enzymic methylation of myelin basic protein in myelin.
Topics: Amino Acids; Animals; Brain; Cattle; Chromatography, Gel; Methylation; Microscopy, Electron; Myelin Basic Protein; Myelin Sheath; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 1991 |
Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells.
Topics: Animals; Cell Line; Cell Survival; DNA Replication; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Methionine; Methionine Adenosyltransferase; Methylation; Models, Biological; Neoplasm Proteins; RNA, Neoplasm; S-Adenosylmethionine; Selenomethionine | 1991 |
Exogenous gangliosides may affect methylation mechanisms in neuronal cell cultures.
Topics: Animals; Brain; Cells, Cultured; Chemical Precipitation; Chick Embryo; Choline; DNA; Ethanolamine; Ethanolamines; Gangliosides; Methionine; Methylation; Molecular Weight; Neurons; Phospholipids; RNA; S-Adenosylmethionine; Sulfur Radioisotopes; Trichloroacetic Acid; Tritium | 1991 |
Carboxylmethylation affects the proteolysis of myelin basic protein by Staphylococcus aureus V8 proteinase.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Chromatography, High Pressure Liquid; Cytosol; Kinetics; Methylation; Molecular Sequence Data; Myelin Basic Protein; Peptide Fragments; Protein O-Methyltransferase; S-Adenosylmethionine; Serine Endopeptidases; Staphylococcus aureus | 1991 |
Leishmania donovani: antagonistic effect of S-adenosyl methionine on ultrastructural changes and growth inhibition induced by sinefungin.
Topics: Adenosine; Animals; Antiprotozoal Agents; Flagella; Golgi Apparatus; Hydrogen-Ion Concentration; Leishmania donovani; Methylation; Microscopy, Electron; Protein O-Methyltransferase; Protozoan Proteins; S-Adenosylmethionine | 1992 |
Twenty-four-hour changes of S-adenosylmethionine, S-adenosylhomocysteine adenosine and their metabolizing enzymes in rat liver; possible physiological significance in phospholipid methylation.
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Liver; Male; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1991 |
Amplification and detection of substrates for protein carboxyl methyltransferases in PC12 cells.
Topics: Adenosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hydrolysis; In Vitro Techniques; Methanol; Methylation; Methyltransferases; Proteins; Rats; S-Adenosylmethionine | 1991 |
Human erythrocyte D-aspartyl/L-isoaspartyl methyltransferases: enzymes that recognize age-damaged proteins.
Topics: Amino Acid Sequence; Aspartic Acid; Blood Proteins; Erythrocyte Aging; Erythrocytes; Isoenzymes; Methylation; Molecular Sequence Data; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylmethionine; Sequence Homology, Nucleic Acid | 1991 |
Protein carboxyl methylation in kidney brush-border membranes.
Topics: Animals; Cell Membrane; Cytosol; Electrophoresis, Polyacrylamide Gel; Gelatin; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Leucine; Male; Methylation; Microvilli; Oligopeptides; Ovalbumin; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1991 |
Role of sulfhydryl groups in phospholipid methylation reactions of cardiac sarcolemma.
Topics: Animals; Cell Fractionation; Dithiothreitol; Heart Ventricles; Kinetics; Male; Membrane Lipids; Methylation; Methyltransferases; Myocardium; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma; Sulfhydryl Compounds | 1991 |
Phenytoin treatment and folate supplementation affect folate concentrations and methylation capacity in rats.
Topics: Animals; Brain; Drug Interactions; Folic Acid; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Phenytoin; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Weight Gain | 1991 |
Effect of cobalamin derivatives on in vitro enzymatic DNA methylation: methylcobalamin can act as a methyl donor.
Topics: Animals; DNA; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spleen; Vitamin B 12 | 1991 |
Enzymatic N-methylation of phenelzine catalyzed by phenylethanolamine N-methyltransferase.
Topics: Adrenal Medulla; Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Hydrazines; Isoelectric Focusing; Liver; Methylation; Phenelzine; Phenylethanolamine N-Methyltransferase; Proteins; Rats; S-Adenosylmethionine | 1991 |
Methylation, acetylation and phosphorylation of the bases of DNA of young and old rats.
Topics: Acetyl Coenzyme A; Acetylation; Adenosine Triphosphate; Aging; Animals; Brain; Cell Nucleus; DNA; Female; Liver; Methylation; Phosphorylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1991 |
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments.
Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin | 1991 |
Identifying the recognition unit for G protein methylation.
Topics: Animals; Cattle; GTP-Binding Proteins; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Structure; Rod Cell Outer Segment; S-Adenosylmethionine; Substrate Specificity; Transducin | 1991 |
Central-nervous-system methyl-group metabolism in children with neurological complications of HIV infection.
Topics: Biopterins; Child, Preschool; Encephalitis; HIV Seropositivity; Humans; Infant; Methionine; Methylation; Neopterin; S-Adenosylmethionine; Tetrahydrofolates | 1990 |
Stereochemical studies of the C-methylation of deoxycytidine catalyzed by HhaI methylase and the N-methylation of deoxyadenosine catalyzed by EcoRI methylase.
Topics: Base Sequence; Deoxyadenosines; Deoxycytidine; DNA; DNA-Cytosine Methylases; Hydrolysis; Methylation; Molecular Sequence Data; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Stereoisomerism; Substrate Specificity | 1991 |
Identification of a highly conserved domain in the EcoRII methyltransferase which can be photolabeled with S-adenosyl-L-[methyl-3H]methionine. Evidence for UV-induced transmethylation of cysteine 186.
Topics: Amino Acid Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Chymotrypsin; Cysteine; DNA-Cytosine Methylases; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Methylation; Molecular Sequence Data; Peptide Mapping; Photochemistry; S-Adenosylmethionine; Trypsin | 1991 |
Evidence that the decarboxylation reaction occurs before the first methylation in ubiquinone biosynthesis in rat liver mitochondria.
Topics: Anaerobiosis; Animals; Chromatography, High Pressure Liquid; Kinetics; Mass Spectrometry; Methylation; Mitochondria, Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Ubiquinone | 1991 |
Procainamide inhibits DNA methyltransferase in a human T cell line.
Topics: Animals; Cell Line; DNA (Cytosine-5-)-Methyltransferases; Methylation; Phospholipids; Procainamide; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; T-Lymphocytes | 1991 |
Inhibitors of membrane transmethylation reactions prevent the lymphocyte chemokinetic response.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Bradykinin; Chemotaxis, Leukocyte; Colchicine; Homocysteine; Humans; Interleukin-16; Leukocytes, Mononuclear; Lymphocytes; Lymphokines; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Second Messenger Systems | 1990 |
The gamma subunit of brain G-proteins is methyl esterified at a C-terminal cysteine.
Topics: Animals; Brain Chemistry; Carboxylic Acids; Cattle; Cell Membrane; Cysteine; Esters; GTP-Binding Proteins; Hydrolysis; Membrane Lipids; Methylation; Protein Binding; S-Adenosylmethionine | 1990 |
Selective carboxyl methylation of structurally altered calmodulins in Xenopus oocytes.
Topics: Animals; Brain; Calcium Chloride; Calmodulin; Cattle; Chickens; Edetic Acid; Escherichia coli; Female; Genetic Variation; Kinetics; Methylation; Oocytes; Recombinant Proteins; S-Adenosylmethionine; Sulfur Radioisotopes; Xenopus | 1990 |
Alterations in phospholipid N-methylation of cardiac subcellular membranes due to experimentally induced diabetes in rats.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardium; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum | 1990 |
Alteration of membrane phospholipid methylation by adenosine analogs does not affect T lymphocyte activation.
Topics: Adenosine; Antigens; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Membrane; Cells, Cultured; Humans; Leukocytes, Mononuclear; Lipids; Lymphocyte Activation; Major Histocompatibility Complex; Methylation; Phospholipids; Receptors, Antigen, T-Cell; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tritium | 1990 |
Increase of GABA-stimulated diazepam binding after lipid methylation in membrane preparations from rat brain.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; Receptors, GABA-A; S-Adenosylmethionine | 1990 |
Phorbol 12-myristate 13-acetate, A23187 and L-adrenaline inhibit phospholipid methylation in human monocytes and lymphocytes. Inhibition is independent of oxyradical production and phospholipid hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Epinephrine; Free Radicals; Humans; Hydrolysis; Isoquinolines; Lymphocytes; Methylation; Monocytes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Piperazines; Protein Kinase Inhibitors; S-Adenosylmethionine; Sodium Fluoride; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli.
Topics: Adenosine; Allosteric Regulation; Base Sequence; Binding Sites; Binding, Competitive; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Sodium Chloride; Temperature; Thermodynamics | 1990 |
[Effect of S-adenosylmethionine on methylation of inorganic arsenic].
Topics: Animals; Arsenic; Arsenic Trioxide; Arsenicals; Cricetinae; Liver; Male; Mesocricetus; Methylation; Oxides; S-Adenosylmethionine | 1990 |
Halothane and isoflurane alter phospholipid transmethylation in rat brain synaptosomes.
Topics: Animals; Brain; Halothane; In Vitro Techniques; Isoflurane; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptosomes | 1990 |
Biosynthesis of vitamin B12: isolation of precorrin-6x, a metal-free precursor of the corrin macrocycle retaining five S-adenosylmethionine-derived peripheral methyl groups.
Topics: Magnetic Resonance Spectroscopy; Methylation; NADP; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1990 |
The E. coli cell surface specifically prevents the initiation of DNA replication at oriC on hemimethylated DNA templates.
Topics: Bacterial Proteins; Cell Membrane; Chromosomes, Bacterial; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Plasmids; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Templates, Genetic | 1990 |
Isocratic high performance liquid chromatographic analysis of S-adenosylmethionine and S-adenosylhomocysteine in animal tissues: the effect of exposure to nitrous oxide.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Liver; Methylation; Nitrous Oxide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 1990 |
Effects of selenomethionine on cell growth and on S-adenosylmethionine metabolism in cultured malignant cells.
Topics: Cell Division; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Nucleotides; S-Adenosylmethionine; Selenium; Selenomethionine; Tumor Cells, Cultured | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described.
Topics: Affinity Labels; Amino Acids; Carbohydrates; Centrifugation, Density Gradient; Cyclosporins; Immunoblotting; Methylation; Mitosporic Fungi; Molecular Weight; Multienzyme Complexes; Pantetheine; Peptide Synthases; Photochemistry; S-Adenosylmethionine; Trichoderma | 1990 |
Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Deoxyadenosines; Electrophoresis, Gel, Two-Dimensional; Methylation; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Pheochromocytoma; Rats; S-Adenosylmethionine; Thionucleosides; Tubercidin; Tumor Cells, Cultured | 1990 |
Alteration of lipid methylation by oleic acid in rat heart sarcolemma.
Topics: Animals; Deoxycholic Acid; Detergents; Dose-Response Relationship, Drug; Heart; Male; Membrane Lipids; Methylation; Methyltransferases; Myocardium; Octoxynol; Oleic Acid; Oleic Acids; Phospholipids; Polyethylene Glycols; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma | 1990 |
Biosynthesis of methanopterin.
Topics: Aniline Compounds; Biopterins; Euryarchaeota; Methionine; Methylation; Neopterin; Organophosphorus Compounds; Pterins; S-Adenosylmethionine | 1990 |
Direct photolabeling of the EcoRII methyltransferase with S-adenosyl-L-methionine.
Topics: Adenosine; Affinity Labels; Azides; Base Sequence; Chemical Precipitation; Dithiothreitol; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Kinetics; Mercaptoethanol; Methylation; Photochemistry; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Trichloroacetic Acid; Ultraviolet Rays | 1990 |
The role of cap methylation in the translational activation of stored maternal histone mRNA in sea urchin embryos.
Topics: Animals; Aphidicolin; Cell Nucleus; Dactinomycin; Diterpenes; Embryo, Nonmammalian; Female; Fertilization; Histones; Methionine; Methylation; Ovum; Protein Biosynthesis; RNA; RNA Caps; RNA, Messenger; S-Adenosylmethionine; Sea Urchins; tRNA Methyltransferases; Zygote | 1985 |
Effects of secretagogues on ATP levels and protein carboxyl methylation in rat brain synaptosomes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Calcimycin; Calcium; Chlorides; Egtazic Acid; Female; In Vitro Techniques; Manganese; Manganese Compounds; Methylation; Ouabain; Potassium; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; Rats; Rats, Inbred Strains; Ruthenium Red; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Cyanide; Synaptosomes; Tritium; Veratridine | 1986 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
Time dependence of the methylation of myelin basic protein from bovine brain; evidence for protein-methylarginine demethylation.
Topics: Animals; Arginine; Brain; Cattle; Kinetics; Methylation; Methyltransferases; Myelin Basic Protein; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 1987 |
Mechanism of the interaction between myelin basic protein and the myelin membrane; the role of arginine methylation.
Topics: Animals; Arginine; Calorimetry; Cattle; Kinetics; Light; Methylation; Myelin Basic Protein; Myelin Sheath; S-Adenosylmethionine; Scattering, Radiation | 1987 |
Site and substrate specificity of the ermC 23S rRNA methyltransferase.
Topics: Bacillus subtilis; Drug Resistance, Microbial; Erythromycin; Kinetics; Methylation; Methyltransferases; Plasmids; RNA, Bacterial; RNA, Ribosomal; S-Adenosylmethionine; Substrate Specificity | 1987 |
Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Methylation; Phospholipids; S-Adenosylmethionine; Theophylline; Tubercidin | 1987 |
Analysis of methylated amino acids by high-performance liquid chromatography: methylation of myelin basic protein.
Topics: Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Histones; Methylation; Myelin Basic Protein; S-Adenosylmethionine | 1987 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.
Topics: Animals; Diethylnitrosamine; Genes, ras; Homocysteine; Immunoblotting; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Discrete interactions between phosphatidylethanolamine-N-methylation and phosphatidylinositolbisphosphate hydrolysis in rat myocardium.
Topics: Adrenergic Agonists; Animals; Cells, Cultured; Hydrolysis; Methylation; Myocardium; Phosphatidylethanolamines; Phosphatidylinositols; Rats; S-Adenosylmethionine; Sarcolemma; Type C Phospholipases | 1989 |
In vitro methylation of CpG-rich islands.
Topics: Base Sequence; Cloning, Molecular; Dinucleoside Phosphates; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; Methylation; Placenta; Pregnancy; S-Adenosylmethionine | 1989 |
SVLM21, a Sindbis virus mutant resistant to methionine deprivation, encodes an altered methyltransferase.
Topics: Animals; Cell Line; Cells, Cultured; Chromatography, Thin Layer; Guanylyl Imidodiphosphate; Kinetics; Methionine; Methylation; Mutation; S-Adenosylmethionine; Sindbis Virus; Temperature; tRNA Methyltransferases; Virus Replication | 1989 |
Effect of toluene on rat synaptosomal phospholipid methylation and membrane fluidity.
Topics: Animals; Brain; Male; Membrane Fluidity; Methionine; Methionine Adenosyltransferase; Methylation; Norepinephrine; Phosphatidylethanolamines; Phospholipids; Propranolol; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Toluene | 1989 |
In vitro methylation of Escherichia coli 16S ribosomal RNA and 30S ribosomes.
Topics: Base Sequence; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Ribonucleosides; Ribosomes; RNA, Ribosomal; RNA, Ribosomal, 16S; S-Adenosylmethionine | 1989 |
Effect of dietary methyl group deficiency on one-carbon metabolism in rats.
Topics: Amino Acids; Animals; Carbon; Choline Deficiency; Diet; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Organ Size; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Weight Gain | 1989 |
Phosphatidylethanolamine N-methyltransferase in human red blood cell membrane preparations. Kinetic mechanism.
Topics: Adult; Erythrocyte Membrane; Humans; Kinetics; Male; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Regulation of S-adenosyl methionine synthesis in the mouse embryo.
Topics: Animals; Binding, Competitive; Blastocyst; Embryo, Mammalian; Ethionine; Homocysteine; Humans; Methionine; Methylation; Mice; Mice, Inbred Strains; Morula; Oocytes; S-Adenosylmethionine | 1989 |
[Enzymatic methyl esterification of the protein in bovine crystalline lens in culture].
Topics: Animals; Cattle; Cell Survival; Eye Proteins; Lens, Crystalline; Methylation; Organ Culture Techniques; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1989 |
Functional analysis of hypomethylation variants of the New Jersey serotype of vesicular stomatitis virus.
Topics: Methylation; Methyltransferases; Mutation; Phenotype; RNA Caps; RNA, Viral; S-Adenosylmethionine; Temperature; Vesiculovirus | 1987 |
Bacteriophage T2 and T4, dam+ and damh and Eco dam+ methylation: preference at different sites.
Topics: Base Sequence; DNA Restriction Enzymes; DNA, Viral; Escherichia coli; Methylation; Mutation; S-Adenosylmethionine; T-Phages | 1988 |
S-adenosyl-L-methionine modulates Na+ + K+-ATPase activity in rat colonic basolateral membranes.
Topics: Animals; Basement Membrane; Benzyl Alcohol; Benzyl Alcohols; Colon; Fluorescence Polarization; Kinetics; Lipid Metabolism; Liposomes; Male; Methanol; Methylation; Phospholipids; Proteins; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase | 1988 |
Cobalamin-dependent methionine synthase from Escherichia coli B: electron paramagnetic resonance spectra of the inactive form and the active methylated form of the enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electron Spin Resonance Spectroscopy; Escherichia coli; Methylation; Methyltransferases; Molecular Weight; Oxidation-Reduction; S-Adenosylmethionine; Vitamin B 12 | 1988 |
Histamine increases phospholipid methylation and H2-receptor-adenylate cyclase coupling in rat brain.
Topics: Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Enzyme Activation; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Histamine H2; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptic Membranes; Tissue Distribution | 1988 |
Deamidation of calmodulin at neutral and alkaline pH: quantitative relationships between ammonia loss and the susceptibility of calmodulin to modification by protein carboxyl methyltransferase.
Topics: Ammonia; Animals; Brain; Calmodulin; Cattle; Hydrogen-Ion Concentration; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Substrate Specificity | 1989 |
Differential methylation patterns in molecular species of phosphatidylethanolamine derivatives in rat liver membranes.
Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Fatty Acids; Female; Intracellular Membranes; Methylation; Microsomes, Liver; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
Topics: Aminopyridines; Animals; Carcinogens; Deoxycytidine; DNA; Homocysteine; Liver; Male; Methapyrilene; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Stimulation of Ca2+-pump in rat heart sarcolemma by phosphatidylethanolamine N-methylation.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Kinetics; Male; Methylation; Methyltransferases; Myocardium; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma | 1986 |
Protective effect of S-adenosylmethionine against the induction of chromosome fragile sites.
Topics: Caffeine; Chromosome Fragile Sites; Chromosome Fragility; DNA Damage; Floxuridine; Humans; Lymphocytes; Methylation; S-Adenosylmethionine | 1987 |
Phosphatidylcholine synthesis in adult Dirofilaria immitis females.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Dirofilaria immitis; Female; Filarioidea; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine | 1985 |
Modulation of the cardiac membrane-bound cyclic nucleotide phosphodiesterase: inhibition due to a contamination of TLC purified S-adenosyl-L-[methyl-3H] methionine by Zn++ ions.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cell Membrane; Chromatography, Thin Layer; Fluorescence; In Vitro Techniques; Male; Methylation; Myocardium; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Zinc | 1985 |
Regulation of mononuclear leukocyte function by transmethylation reactions.
Topics: Animals; Cell Migration Inhibition; Enzyme Activation; Guinea Pigs; Homocysteine; Macrophages; Methylation; Oxygen; Phospholipases; S-Adenosylmethionine; Superoxides | 1985 |
Decreased methylation rates of DNA in SV40-transformed human fibroblasts.
Topics: Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Methionine; Methylation; S-Adenosylmethionine; Simian virus 40 | 1986 |
Regulation of Na+-H+ exchange by transmethylation reactions in rat colonic brush-border membranes.
Topics: Animals; Carrier Proteins; Colon; Fluorescence Polarization; Hydrogen; In Vitro Techniques; Intestinal Mucosa; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Methylation; Microvilli; Phospholipids; Rats; S-Adenosylmethionine; Sodium; Sodium-Hydrogen Exchangers | 1986 |
Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro.
Topics: Animals; Bucladesine; Cell Membrane; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Homocysteine; Leydig Cells; Luteinizing Hormone; Male; Methylation; Rats; Receptors, LH; S-Adenosylhomocysteine; S-Adenosylmethionine; Testosterone | 1987 |
EcoR124 and EcoR124/3: the first members of a new family of type I restriction and modification systems.
Topics: Adenosine Triphosphatases; Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; Genes; Isoenzymes; Macromolecular Substances; Methylation; Plasmids; S-Adenosylmethionine; Transcription, Genetic; Transformation, Genetic | 1987 |
Biosynthesis of methylphosphomannosyl residues in the oligosaccharides of Dictyostelium discoideum glycoproteins. Evidence that the methyl group is derived from methionine.
Topics: Amidohydrolases; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dictyostelium; Glycoproteins; Glycoside Hydrolases; Hexosephosphates; Hydrogen-Ion Concentration; Kinetics; Mannosephosphates; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Methionine; Methylation; Oligosaccharides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phosphorylation; S-Adenosylmethionine | 1986 |
Enzymatic basis for the calcium-induced decrease of membrane protein methyl esterification in intact erythrocytes. Evidence for an impairment of S-adenosylmethionine synthesis.
Topics: Adenosine Triphosphate; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aging; Erythrocyte Membrane; Humans; Membrane Proteins; Methionine Adenosyltransferase; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Protein Processing, Post-Translational; S-Adenosylmethionine | 1986 |
Selective augmentation by recombinant interferon-gamma of the intracellular content of S-adenosylmethionine in murine macrophages.
Topics: Adjuvants, Immunologic; Animals; Cytotoxicity, Immunologic; Female; Interferon-gamma; Intracellular Fluid; Macrophage Activation; Macrophages; Methylation; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phospholipids; Recombinant Proteins; S-Adenosylmethionine | 1986 |
An ethA mutation in Bacillus subtilis 168 permits induction of sporulation by ethionine and increases DNA modification of bacteriophage phi 105.
Topics: Adenosine; Bacillus subtilis; Bacteriophages; DNA, Viral; Ethionine; Methionine; Methylation; Mutation; S-Adenosylmethionine; Spores, Bacterial | 1986 |
Effect of exogenous histone H5 on integration of histone H1 in rat liver chromatin. Correlations with aberrant epsilon-N-methylation of histone H1.
Topics: Animals; Binding Sites; Chickens; Chromatin; Histones; Liver; Lysine; Methylation; Methyltransferases; Nucleosomes; Polylysine; Rats; S-Adenosylmethionine; Salmine | 1986 |
Effect of chronic valproate treatment on folate-dependent methyl biosynthesis in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Liver; Male; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Valproic Acid | 1986 |
Effect of retinol toxicity on hepatic S-adenosylmethionine-dependent transmethylation in rats.
Topics: Amino Acids, Sulfur; Animals; Carbon Dioxide; Diet; Liver; Male; Methylation; Oxidation-Reduction; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Vitamin A | 1987 |
S-adenosylmethionine and transmethylation reactions in trichomonads.
Topics: Animals; Chromatography, High Pressure Liquid; Crithidia; Eukaryota; Leishmania; Leishmania mexicana; Methionine; Methylation; S-Adenosylmethionine; Trichomonas vaginalis; Tritrichomonas; Trypanosomatina | 1987 |
Effect of alpha-difluoromethylornithine on DNA methylation in murine erythroleukaemic cells. Relationship to stimulation of induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; DNA; Eflornithine; Leukemia, Erythroblastic, Acute; Methylation; Mice; S-Adenosylmethionine; Stimulation, Chemical | 1987 |
Carboxylmethylation of calmodulin in cultured pituitary cells.
Topics: Calcium; Calmodulin; Cell Line; Chemical Fractionation; Chromatography, High Pressure Liquid; Cycloheximide; Cytosol; Egtazic Acid; Kinetics; Methionine; Methionine Adenosyltransferase; Methylation; Pituitary Gland; S-Adenosylmethionine | 1987 |
Rates of oxidation of the methionine and S-adenosylmethionine methyl carbons in isolated rat hepatocytes.
Topics: Animals; Carbon Dioxide; Kinetics; Liver; Male; Methionine; Methylation; Oxidation-Reduction; Rats; S-Adenosylmethionine | 1987 |
Increased SR phospholipid N-methylation in skeletal muscle of diabetic rats.
Topics: Adenosine Triphosphate; Animals; Calcium; Calmodulin; Diabetes Mellitus, Experimental; Egtazic Acid; Kinetics; Male; Methylation; Microsomes; Muscles; p-Methoxy-N-methylphenethylamine; Phospholipids; Rats; Rats, Inbred Strains; Reference Values; S-Adenosylmethionine; Sarcoplasmic Reticulum | 1988 |
Neisseria gonorrhoeae M.Ngo AI DNA methyltransferase: physical and catalytic properties of the homogeneous enzyme.
Topics: Bacterial Proteins; DNA, Bacterial; Kinetics; Methylation; Molecular Weight; Neisseria gonorrhoeae; S-Adenosylmethionine; Substrate Specificity | 1988 |
Activation of Ca2+-stimulated ATPase by phospholipid N-methylation in cardiac sarcoplasmic reticulum.
Topics: Animals; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Cell-Free System; Enzyme Activation; Imidoesters; Membrane Lipids; Methylation; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Sarcoplasmic Reticulum | 1985 |
Identification of glutathione S-transferase as a substrate and glutathione as an inhibitor of in vitro calmodulin-stimulated protein methylation in rat liver cytosol.
Topics: Animals; Calmodulin; Cytosol; Glutathione; Glutathione Transferase; Kinetics; Liver; Male; Methylation; Molecular Weight; Proteins; Rats; Reference Values; S-Adenosylmethionine | 1988 |
Guanine nucleotide-dependent carboxyl methylation of mammalian membrane proteins.
Topics: Animals; Brain; Cell Line; Guanosine Triphosphate; Humans; Kinetics; Liver; Membrane Proteins; Methylation; Molecular Weight; Protein Methyltransferases; S-Adenosylmethionine | 1988 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
Phospholipid methylation participates in H2-receptor mediated stimulation of adenylate cyclase in rat brain.
Topics: Adenylyl Cyclases; Animals; Brain; Histamine; Kinetics; Male; Methylation; Mitochondria; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Histamine H2; S-Adenosylmethionine; Signal Transduction; Synaptic Membranes | 1988 |
Phosphatidylcholine synthesis in yeast.
Topics: Choline; Cytidine Diphosphate Choline; Ethionine; Methionine; Methylation; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae | 1988 |
Expression of the cloned coliphage T3 S-adenosylmethionine hydrolase gene inhibits DNA methylation and polyamine biosynthesis in Escherichia coli.
Topics: Cloning, Molecular; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; Escherichia coli; Genes, Viral; Hydrolases; Methylation; S-Adenosylmethionine; Spermidine; T-Phages | 1987 |
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XVIII. Biomethylation and differentiation.
Topics: Animals; Carcinogens; Cell Differentiation; Chromatin; Fetal Proteins; Gene Expression Regulation; Genes, Viral; Humans; Methylation; Models, Biological; S-Adenosylmethionine; tRNA Methyltransferases | 1987 |
Catalytic mechanism and inhibition of tRNA (uracil-5-)methyltransferase: evidence for covalent catalysis.
Topics: Aminobutyrates; Escherichia coli; Fluorouracil; Kinetics; Methylation; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium; tRNA Methyltransferases | 1987 |
S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat.
Topics: Animals; Cell Membrane; Cell Survival; Cytidine Diphosphate Choline; Hippocampus; Ischemic Attack, Transient; Male; Methionine; Methylation; Necrosis; Nerve Degeneration; Neurons; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
High levels of protein carboxyl methyltransferase in well-differentiated human endometrial carcinoma.
Topics: Endometrium; Female; Humans; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Uterine Neoplasms | 1988 |
Protein methylation inhibits Na+-Ca2+ exchange activity in cardiac sarcolemmal vesicles.
Topics: Animals; Calcium; Carrier Proteins; Cell Fractionation; Cholesterol; Dogs; Kinetics; Liposomes; Methylation; Myocardium; S-Adenosylmethionine; Sarcolemma; Sodium-Calcium Exchanger | 1988 |
DNA (cytosine) methylation in murine and human tumor cell lines treated with S-adenosylhomocysteine hydrolase inhibitors.
Topics: Adenosine; Adenosylhomocysteinase; Animals; DNA, Neoplasm; Humans; Hydrolases; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin; Tumor Cells, Cultured | 1988 |
Partial purification, characterization, and kinetic analysis of isoflavone 5-O-methyltransferase from yellow lupin roots.
Topics: Cations, Divalent; Methylation; Methyltransferases; Plant Proteins; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Reagents | 1988 |
DNA methylating capacity in metastatic variants of a human melanoma cell line.
Topics: Cell Line; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Genetic Variation; Humans; Melanoma; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
The carboxylmethylation of membrane-bound proteins in the aging rat brain.
Topics: Aging; Animals; Brain; Kinetics; Male; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptic Membranes | 1988 |
Biosynthesis of mevinolin, a hypocholesterolemic fungal metabolite, in Aspergillus terreus.
Topics: Anticholesteremic Agents; Aspergillus; Butyrates; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Lovastatin; Methionine; Methylation; S-Adenosylmethionine; T-2 Toxin; Tritium | 1987 |
Relative effects of S-adenosylmethionine depletion on nucleic acid methylation and polyamine biosynthesis.
Topics: Aminobutyrates; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Nucleic Acids; Polyamines; S-Adenosylmethionine | 1987 |
Methylation of cytosolic proteins may be a possible biochemical pathway of early aldosterone action in cultured renal collecting duct cells.
Topics: Aldosterone; Animals; Cells, Cultured; Cytosol; Electrophoresis, Polyacrylamide Gel; Kidney Tubules; Kidney Tubules, Collecting; Methylation; Molecular Weight; Proteins; Rabbits; S-Adenosylmethionine; Subcellular Fractions | 1987 |
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets.
Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1986 |
S-methyl glutathione synthesis is catalyzed by the cheR methyltransferase in Escherichia coli.
Topics: Chemotaxis; Escherichia coli; Glutathione; Methylation; Methyltransferases; S-Adenosylmethionine | 1986 |
Kinetic and catalytic mechanism of HhaI methyltransferase.
Topics: Binding Sites; Catalysis; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Kinetics; Methylation; Nucleic Acid Conformation; Polydeoxyribonucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium | 1987 |
Periodate-oxidized adenosine inhibits the formation of dimethylselenide and trimethylselenonium ion in mice treated with selenite.
Topics: Adenosine; Animals; Inactivation, Metabolic; Kinetics; Liver; Methylation; Mice; Organometallic Compounds; Organoselenium Compounds; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenious Acid; Selenium; Selenium Compounds | 1987 |
Comparison of basal and noradrenaline stimulated methylation of chloroform-extractable products in synaptosomal preparations from the rat brain.
Topics: Animals; Brain; Carbon Tetrachloride; Kinetics; Magnesium; Magnesium Chloride; Methylation; Norepinephrine; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Synaptosomes | 1987 |
Calmodulin as an activator and a substrate of methyltransferase enzymes.
Topics: Animals; Calmodulin; Cytosol; Kinetics; Liver; Male; Methylation; Molecular Weight; Organ Specificity; Protein Methyltransferases; Proteins; Rats; S-Adenosylmethionine | 1987 |
Identification and partial characterization of phospholipid methylation in rat small-intestinal brush-border membranes.
Topics: Animals; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Male; Methylation; Microvilli; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1987 |
Methylation at specific altered aspartyl and asparaginyl residues in glucagon by the erythrocyte protein carboxyl methyltransferase.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Brain; Chymotrypsin; Erythrocytes; Glucagon; Humans; Methylation; Peptide Fragments; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Substrate Specificity; Trypsin | 1987 |
Light-regulated methylation of chloroplast proteins.
Topics: Chloroplasts; Kinetics; Light; Methylation; Molecular Weight; Plant Proteins; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1987 |
Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Kinetics; Methionine; Methylation; Molecular Weight; Oocytes; S-Adenosylmethionine; Xenopus laevis | 1987 |
Structure of a polysaccharide containing galactose and galacturonic acid from Rhizobium meliloti. Characterization and partial purification of a 2-O-methyltransferase.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Galactose; Hexuronic Acids; Hydrogen-Ion Concentration; Magnesium; Manganese; Methylation; Methyltransferases; Polysaccharides; Rhizobium; S-Adenosylmethionine; Uronic Acids | 1987 |
On the role of O-methylation in the metabolism of S-adenosylmethionine in rat brain.
Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cerebral Cortex; Corpus Striatum; Cycloheptanes; Dose-Response Relationship, Drug; Female; Methylation; Mice; Psychotropic Drugs; Pyrogallol; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tropolone | 1987 |
Human DNA (cytosine-5)methyltransferase selectively methylates duplex DNA containing mispairs.
Topics: Base Composition; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; Indicators and Reagents; Methylation; Oligodeoxyribonucleotides; Placenta; S-Adenosylmethionine; Tritium | 1987 |
Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Fatty Acids; Male; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1987 |
Phospholipid methylation in canine myocardium: kinetic characteristics and the effect of endotoxin administration.
Topics: Animals; Dogs; Endotoxins; Female; Heart; Hydrogen-Ion Concentration; Kinetics; Male; Methylation; Myocardium; Phospholipids; S-Adenosylmethionine; Shock, Septic | 1987 |
Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Kidney; Kinetics; Lyases; Male; Methylation; Microsomes; Microsomes, Liver; S-Adenosylmethionine; Spironolactone | 1987 |
In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway.
Topics: Animals; Brain; Injections, Intraventricular; Male; Methylation; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Subcellular Fractions | 1987 |
Effect of modification of membrane phospholipid composition on phospholipid methylation in aggregating cell culture.
Topics: Animals; Brain; Cell Aggregation; Cells, Cultured; Deanol; Ethanolamines; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1986 |
S-adenosyl-L-methionine modulates phosphatidylethanolamine methyltransferase response to isoproterenol in brain.
Topics: Animals; Brain; Chromatography, Thin Layer; In Vitro Techniques; Isoproterenol; Male; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1986 |
Effect of pyridoxine deficiency on phospholipid methylation in rat liver microsomes.
Topics: Adenosine; Animals; Carbon Radioisotopes; Kinetics; Male; Methylation; Microsomes, Liver; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1986 |
N-methylation and quaternization of pyridine in vitro by rabbit lung, liver and kidney N-methyltransferases: an S-adenosyl-L-methionine-dependent reaction.
Topics: Animals; Chromatography, High Pressure Liquid; Kidney; Liver; Lung; Male; Methylation; Methyltransferases; Pyridines; Pyridinium Compounds; Rabbits; S-Adenosylmethionine | 1986 |
[DNA-methylation: signal for gene regulation].
Topics: 5-Methylcytosine; Animals; Cytosine; Gene Expression Regulation; Humans; Methylation; S-Adenosylmethionine | 1986 |
The effect of dietary and chemically induced methylation deficiency on the metabolism of arsenate in the rabbit.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Choline Deficiency; Inactivation, Metabolic; Male; Metabolic Clearance Rate; Methylation; Rabbits; S-Adenosylmethionine; Tissue Distribution | 1986 |
Estradiol activates methylating enzyme(s) involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in rat pituitary membranes.
Topics: Animals; Cell Compartmentation; Cell Membrane; Enzyme Activation; Estradiol; Female; Hydrogen-Ion Concentration; Hypothalamo-Hypophyseal System; Kinetics; Magnesium; Methylation; Methyltransferases; Ovariectomy; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Pituitary Gland; Rats; S-Adenosylmethionine; Tissue Distribution | 1986 |
Changes in methionine metabolism induced by D-galactosamine in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Carbon Radioisotopes; Galactosamine; In Vitro Techniques; Liver; Methionine; Methylation; Rats; S-Adenosylmethionine | 1986 |
Quantitative evaluation and regulation of S-adenosylmethionine-dependent transmethylation in sheep tissues.
Topics: Animals; Female; Homeostasis; Hydrolysis; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sheep; Tissue Distribution | 1986 |
Formation of formaldehyde from S-adenosyl-L-[methyl-3H]methionine during enzymic transmethylation of histamine.
Topics: Animals; Formaldehyde; Histamine; Histamine N-Methyltransferase; Kidney; Kinetics; Methylation; Methyltransferases; Rats; S-Adenosylmethionine | 1986 |
Enzymatic protein carboxyl methylation in rat posterior pituitary: neurophysins in rapid-turnover pool determine methyl accepting capacity.
Topics: Animals; Colchicine; Electrophoresis, Polyacrylamide Gel; Male; Methylation; Neurophysins; Pituitary Gland, Posterior; Potassium; Rats; S-Adenosylmethionine; Veratridine | 1987 |
Membrane methylation in isolated rat testis interstitial cells unmasks functional luteinizing hormone receptors.
Topics: Animals; Cell Membrane; Cell Survival; Chorionic Gonadotropin; In Vitro Techniques; Luteinizing Hormone; Male; Membrane Lipids; Methylation; Rats; Receptors, LH; S-Adenosylmethionine; Testis; Testosterone | 1987 |
Inhibition of murine erythroleukemia cell differentiation by 3-deazaadenosine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Differentiation; Cell Line; Deoxyadenosines; Dimethyl Sulfoxide; DNA; Leukemia, Erythroblastic, Acute; Methylation; Mice; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Unmasking of insulin receptors in rat submaxillary gland microsomes: effect of high ionic strength, phospholipase C and S-adenosyl-L-methionine.
Topics: Animals; Female; In Vitro Techniques; Insulin; Kinetics; Male; Methylation; Microsomes; Osmolar Concentration; Phospholipases; Rats; Receptor, Insulin; S-Adenosylmethionine; Submandibular Gland; Type C Phospholipases | 1985 |
Sterol control of the phosphatidylethanolamine-phosphatidylcholine conversion in the yeast mutant GL7.
Topics: Adenosine Triphosphate; Amphotericin B; Cell Membrane; Cholesterol; Ergosterol; Filipin; Methylation; Methyltransferases; Mutation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phosphorylation; S-Adenosylmethionine; Saccharomyces cerevisiae | 1985 |
Purification and characterization of some metabolic effects of S-neplanocylmethionine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Escherichia coli; Kinetics; L Cells; Male; Methionine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylmethionine; Substrate Specificity | 1985 |
Biochemical transmethylation of lipids and neuropeptidergic stimulation of pituitary hormone secretion.
Topics: Animals; Cell Membrane; Gonadotropin-Releasing Hormone; Male; Methylation; Phospholipids; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thyrotropin; Thyrotropin-Releasing Hormone | 1985 |
Stimulation of protein methylase II from Torpedo marmorata by cholinergic effectors.
Topics: Animals; Bungarotoxins; Carbachol; Cell Membrane; Cytosol; Electric Organ; Gallamine Triethiodide; Kinetics; Methylation; Phosphates; Phospholipases A; Phospholipases A2; Protein Methyltransferases; Protein O-Methyltransferase; Receptors, Cholinergic; S-Adenosylmethionine; Torpedo | 1986 |
Synthesis of phosphatidylcholine by two distinct methyltransferases in rat colonic brush-border membranes: evidence for extrinsic and intrinsic membrane activities.
Topics: Adenosine Triphosphate; Animals; Cations, Divalent; Colon; In Vitro Techniques; Intestinal Mucosa; Male; Methylation; Methyltransferases; Microvilli; Octoxynol; Phosphatidylcholines; Phospholipids; Polyethylene Glycols; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Subcellular Fractions; Temperature; Time Factors | 1986 |
Bioalkylation of dibenz[a,b]anthracene in rat liver cytosol.
Topics: Animals; Benz(a)Anthracenes; Biotransformation; Chromatography, High Pressure Liquid; Cytosol; Gas Chromatography-Mass Spectrometry; Liver; Male; Methylation; Oxidation-Reduction; Rats; S-Adenosylmethionine | 1986 |
Stereospecific in vitro N-methylation of nicotine in guinea pig tissues by an S-adenosylmethionine-dependent N-methyltransferase.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Methylation; Methyltransferases; Nicotine; S-Adenosylmethionine; Stereoisomerism | 1985 |
Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver.
Topics: Amino Acids, Sulfur; Animals; Chromatography; DNA; In Vitro Techniques; Liver; Male; Methionine; Methylation; Microsomes, Liver; Perfusion; Phospholipids; Protein Biosynthesis; Rats; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1985 |
Chemical methylation of phosphatidylethanolamine by S-adenosylmethionine.
Topics: Animals; Brain; Hydrogen-Ion Concentration; Methylation; Microsomes; Myelin Sheath; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1985 |
[Determination of DNA methylase activity in animal tissue extracts].
Topics: Adsorption; Animals; Cattle; Cattle Diseases; DNA; DNA (Cytosine-5-)-Methyltransferases; Female; Hydrolysis; In Vitro Techniques; Leukemia; Lymphocytes; Male; Methods; Methylation; Methyltransferases; S-Adenosylmethionine; Spleen; Tissue Extracts; Tritium | 1985 |
Evidence for three catalytic sites in heart sarcolemmal phospholipid N-methylation.
Topics: Animals; Catalysis; Chemical Phenomena; Chemistry; Kinetics; Magnesium; Male; Methylation; Methyltransferases; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma | 1985 |
Nonintracellular, cell-associated O-methylation of isoproterenol in the isolated rabbit thoracic aorta.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium; Catechol O-Methyltransferase; In Vitro Techniques; Isoproterenol; Male; Methylation; Phenoxybenzamine; Rabbits; S-Adenosylmethionine; Stereoisomerism; Tritium | 1985 |
Enzymatic protein carboxyl methylation at physiological pH: cyclic imide formation explains rapid methyl turnover.
Topics: Animals; Cattle; Cerebral Cortex; Hydrogen-Ion Concentration; Imides; Kinetics; Mathematics; Methylation; Models, Biological; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Thermodynamics | 1985 |
Study of inorganic arsenic methylation by rat liver in vitro: relevance for the interpretation of observations in man.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Coenzymes; Cytosol; Enzyme Inhibitors; Glutathione; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1985 |
Protein carboxyl methyltransferase selectively modifies an atypical form of calmodulin. Evidence for methylation at deamidated asparagine residues.
Topics: Animals; Asparagine; Brain; Calmodulin; Cattle; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoenzymes; Kinetics; Methylation; Molecular Weight; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1985 |
Ethanol-induced alterations in rat synaptosomal plasma membrane phospholipids. Relationship to changes in the phospholipid methyltransferases.
Topics: Animals; Ethanol; Humans; Kinetics; Male; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; S-Adenosylmethionine; Substance Withdrawal Syndrome; Synaptosomes | 1985 |
On the mechanism and inhibition of DNA cytosine methyltransferases.
Topics: Base Sequence; Deoxyribonuclease I; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Methylation; Polydeoxyribonucleotides; S-Adenosylmethionine; Thymidylate Synthase; Tritium | 1985 |
Altered regulation of S-adenosylmethionine dependent methylation in adenosine deaminase deficiency.
Topics: Adenosine Deaminase; Animals; Cell Line; Child; Homeostasis; Humans; Kinetics; Methylation; Nucleoside Deaminases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
The role of S-adenosylhomocysteine in the biological utilization of S-adenosylmethionine.
Topics: Alcaligenes; Animals; Dictyostelium; Homocysteine; Humans; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Protein carboxyl methylation-demethylation in rat thymocytes.
Topics: Animals; Carbon Radioisotopes; Kinetics; Methanol; Methionine; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Thymus Gland; Tritium | 1985 |
Methionine metabolism and cancer.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Gene Expression Regulation; Mammals; Methionine; Methylation; Methyltransferases; Models, Biological; Neoplasms; S-Adenosylmethionine | 1985 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
Effects of DNA binding proteins on DNA methylation in vitro.
Topics: Animals; Cell Nucleus; Chromatin; DNA-Binding Proteins; DNA, Neoplasm; Histones; Leukemia L1210; Methylation; Mice; S-Adenosylmethionine; Tritium | 1985 |
Estradiol- and testosterone-induced alterations in phosphatidylcholine and triglyceride synthesis in hepatic endoplasmic reticulum.
Topics: Acyltransferases; Animal Nutritional Physiological Phenomena; Animals; Benzoates; Body Weight; Carbon Isotopes; Castration; Choline; Coenzyme A; Cytosine Nucleotides; Depression, Chemical; Diet; Endoplasmic Reticulum; Estradiol; Female; Glycerides; Injections, Subcutaneous; Lipotropic Agents; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phosphotransferases; Propionates; Rats; S-Adenosylmethionine; Stimulation, Chemical; Testosterone; Triglycerides | 1971 |
Effects of adrenergic agents, theophylline and other drugs on dextran edema and histamine release in rats.
Topics: Animals; Blood Glucose; Bucladesine; Carbon Radioisotopes; Dextrans; Edema; Epinephrine; Female; Histamine; Histamine Release; Hyperglycemia; Isoproterenol; Methylation; Methyltransferases; Norepinephrine; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Rats; S-Adenosylmethionine; Skin; Sympathomimetics; Theophylline; Time Factors | 1974 |
Specificity of enzyme and methyl donor for methylation reactions.
Topics: Animals; Brain; Catechol O-Methyltransferase; Chromatography, DEAE-Cellulose; Chromatography, Gel; Histamine; Indoles; Methylation; Methyltransferases; Phenethylamines; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1973 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Catecholamines: strain differences in biosynthetic enzyme activity in mice.
Topics: Adrenal Glands; Animals; Brain; Carbon Isotopes; Catecholamines; Dihydroxyphenylalanine; Epinephrine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Norepinephrine; Phenylethanolamine N-Methyltransferase; S-Adenosylmethionine; Tyrosine 3-Monooxygenase | 1972 |
Irreversible binding of ethynylestradiol metabolites to protein: lack of methylation by S-adenosyl-methionine.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Catechol O-Methyltransferase; Chromatography, Gel; Cytosol; Ethinyl Estradiol; Glutathione; Isotope Labeling; Liver; Methylation; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rats; Receptors, Drug; S-Adenosylmethionine; Tritium | 1974 |
Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Media; Folic Acid; Formates; Lacticaseibacillus casei; Ligases; Methionine; Methylation; Pediococcus; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Tetrahydrofolates; Transferases | 1972 |
A sensitive assay for the determination of dopamine in plasma.
Topics: Adult; Age Factors; Aged; Aluminum; Ascorbic Acid; Buffers; Carbon Radioisotopes; Catechol O-Methyltransferase; Chromatography, Thin Layer; Dopamine; Edetic Acid; Female; Humans; Hydrogen-Ion Concentration; Ion Exchange; Male; Methods; Methylation; Middle Aged; S-Adenosylmethionine; Sex Factors; Tritium; Tyramine | 1973 |
[Influence of S-adenosylmethionine on the methylation of the RNA by dimethylnitrosamine in vivo].
Topics: Adenine; Animals; Body Weight; Carbon Isotopes; Chromatography, Ion Exchange; Female; Guanine; Hydrochloric Acid; Hydrolysis; Injections, Intravenous; Liver; Male; Methionine; Methylation; Mice; Nitrosamines; Nucleosides; Rats; RNA; S-Adenosylmethionine; Spectrophotometry; Tritium | 1970 |
[Enzymatic methylation of L-ascorbic acid].
Topics: Ascorbic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases | 1970 |
[Research on the enzymatic transmethylation of norepinephrine in the axillary bodies of the small dogfish (Scyliorhinus canicula). I. Study of the methyl donor].
Topics: Adenosine Triphosphate; Animals; Carbon; Carbon Isotopes; Chromaffin System; Epinephrine; In Vitro Techniques; Methionine; Methylation; Norepinephrine; S-Adenosylmethionine; Sharks | 1971 |
Enzymatic methylation of transfer RNA by extracts of polyoma virus-transformed cells.
Topics: Animals; Carbon Isotopes; Cell Line; Cricetinae; Culture Techniques; Escherichia coli; Hydrogen-Ion Concentration; Kidney; Liver; Methylation; Methyltransferases; Mice; Polyomavirus; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Transformation, Genetic | 1970 |
Transfer RNA methylase alterations in polyoma transformed rat embryo culture cells.
Topics: Acetates; Animals; Biological Assay; Cell Transformation, Neoplastic; Culture Techniques; Escherichia coli; Methylation; Polyomavirus; Quaternary Ammonium Compounds; Rats; RNA, Transfer; S-Adenosylmethionine; Transferases; Yeasts | 1971 |
Protein methylases in hepatomas.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Histones; Liver Neoplasms; Methylation; Methyltransferases; Neoplasm Proteins; Neoplasms, Experimental; Rats; S-Adenosylmethionine | 1972 |
N-Methylation of dopamine to epinine in adrenal medulla: a new model for the biosynthesis of adrenaline.
Topics: Adrenal Medulla; Amino Alcohols; Animals; Cattle; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Dopamine; Dopamine beta-Hydroxylase; Epinephrine; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Methylation; Methyltransferases; Models, Biological; Normetanephrine; Phenethylamines; Phosphoric Monoester Hydrolases; S-Adenosylmethionine | 1972 |
Enzymic modification of chromosomal macromolecules. 3. The effect of adenine nucleotides on histone modification in chromatin and a possible influence of steroid hormones.
Topics: Acyltransferases; Adenosine Monophosphate; Adenylyl Cyclases; Androstanes; Animals; Carcinoma, Krebs 2; Cholesterol; Chromatin; Cyclic AMP; Enzyme Activation; Estradiol; Estrone; Histones; Hydrocortisone; Ketosteroids; Methylation; Methyltransferases; Phosphodiesterase Inhibitors; Phosphorus Isotopes; Phosphotransferases; Progesterone; S-Adenosylmethionine; Testosterone; Tritium | 1971 |
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver.
Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium | 1972 |
Enzymatic DNA modifications in isolated nuclei from developing sea urchin embryos.
Topics: Adenine; Aminohydrolases; Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Chromatography, Paper; Cytosine; Cytosine Nucleotides; DNA; Electron Transport Complex IV; Formates; Guanine; Hot Temperature; Methionine; Methylation; Methyltransferases; Proteins; S-Adenosylmethionine; Sea Urchins; Thymidine; Thymine; Tritium | 1972 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |
2'-O-methylation of adenosine, guanosine, uridine, and cytidine in RNA of isolated rat liver nuclei.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Animals; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosine Nucleotides; Guanine Nucleotides; Hydrolysis; Kinetics; Liver; Methyl Ethers; Methylation; Phosphoric Diester Hydrolases; Plants; Polynucleotides; Rats; RNA; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Tritium; Uracil Nucleotides | 1972 |
The contrast between the methylation of transfer ribonucleic acid in vivo and in vitro by normal and SV40 transformed 3T3 cells.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chromatography; Chromatography, DEAE-Cellulose; Clone Cells; Cytoplasm; Electrophoresis; Escherichia coli; Fibroblasts; Methylation; Mice; Mice, Inbred BALB C; Oligonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Simian virus 40; Tritium | 1972 |
Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma.
Topics: Amino Acids; Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Escherichia coli; Female; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Muscles; Mycoplasma; Neoplasms, Experimental; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Spleen | 1973 |
Alteration in tRNA methyltransferase activity in mengovirus infection: host range specificity.
Topics: Animals; Carbon Radioisotopes; Cattle; HeLa Cells; Humans; Kidney; L Cells; Mengovirus; Methylation; Mice; Nucleotides; Oligonucleotides; Phosphorus Radioisotopes; Ribonucleases; RNA, Transfer; RNA, Viral; S-Adenosylmethionine; Species Specificity; Time Factors; tRNA Methyltransferases | 1973 |
Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase.
Topics: Adenosine Monophosphate; Base Sequence; Binding Sites; Chromatography, Paper; Deoxyribonucleases; DNA; DNA, Viral; Electrophoresis, Paper; Endonucleases; Fluoroacetates; Methylation; Methyltransferases; Nucleotides; Oligonucleotides; Phosphorus Radioisotopes; Phosphotransferases; Polynucleotide Ligases; Polynucleotides; S-Adenosylmethionine; Simian virus 40; Structure-Activity Relationship; Tritium | 1974 |
Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.
Topics: Acridines; Adenine; Adenosine; Animals; Arginine; Azo Compounds; Carbon Radioisotopes; Carcinogens; Cytoplasm; Dimethylformamide; Ethidium; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Male; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.
Topics: Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; DNA-Directed RNA Polymerases; Homocysteine; Methylation; Phosphorus Radioisotopes; Ribonucleotides; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Tritium; Uracil Nucleotides; Vesicular stomatitis Indiana virus; Viral Proteins | 1974 |
Neurophysin methylation in extracts of bovine posterior pituitary gland: hormone binding ability.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Cattle; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Lysine; Methylation; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Protein Binding; Receptors, Cell Surface; S-Adenosylmethionine; Vasopressins | 1974 |
Effect of ethionine on the synthesis and transfer of active methyl groups.
Topics: Animals; Bacillus subtilis; Carcinoma, Hepatocellular; Cricetinae; Escherichia coli; Ethionine; Female; Liver; Liver Neoplasms; Male; Methylation; Mice; Quaternary Ammonium Compounds; Rats; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 1972 |
Studies on ubiquinone. Demonstration of the total biosynthesis of ubiquinone-9 in rat liver mitochondria.
Topics: Adenosine Triphosphate; Animals; Benzoates; Carbon Radioisotopes; Coenzyme A; Cyanides; Cytosol; Hydroxylation; Liver; Male; Membranes; Methyl Ethers; Methylation; Microsomes, Liver; Mitochondria, Liver; Models, Chemical; Phenols; Rats; S-Adenosylmethionine; Solubility; Subcellular Fractions; Succinates; Tritium; Ubiquinone; Ultrasonics | 1974 |
Biosynthesis of methylheptadecanes in Anabaena variabilis. In vitro incorporation of S-(methyl- 14 C)adenosylmethionine.
Topics: Adenosine; Alkanes; Bile Acids and Salts; Carbon Isotopes; Cariostatic Agents; Chromatography; Chromatography, Gas; Copper; Cyanobacteria; Dithiothreitol; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Methylation; Muramidase; NADP; Pyridinium Compounds; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Surface-Active Agents; Vibration; Zinc | 1972 |
N-Methyldopamine (epinine), a precursor of adrenaline in the adrenal medulla.
Topics: Adrenal Medulla; Dopa Decarboxylase; Dopamine; Dopamine beta-Hydroxylase; Edetic Acid; Epinephrine; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; S-Adenosylmethionine; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1972 |
5,6-Dihydroxytryptamine is a substrate for catechol O-methyltransferase.
Topics: Animals; Brain; Carbon Radioisotopes; Catechol O-Methyltransferase; Catechols; In Vitro Techniques; Liver; Methylation; Rats; S-Adenosylmethionine; Tryptamines | 1974 |
Changes in histone methylase activity of rat brain and liver with ageing.
Topics: Aging; Animals; Brain; Cell Nucleus; Histones; Liver; Methylation; Methyltransferases; Rats; S-Adenosylmethionine | 1974 |
Inhibitors of histone methylation.
Topics: Animals; Biogenic Amines; Carbon Radioisotopes; Cattle; Deoxyribonucleases; Ethidium; Histones; Kinetics; Methylation; Methyltransferases; Phenethylamines; S-Adenosylmethionine; Spermidine; Spermine; Structure-Activity Relationship; Thymus Gland | 1974 |
Letter: Evidence for O-methylation of catechol estrogen 2-glucuronoside with retention of conjugate in the rat.
Topics: Animals; Carbon Radioisotopes; Catechols; Cattle; Estrogens; Glucuronates; Hydrolysis; In Vitro Techniques; Liver; Male; Methylation; Rats; S-Adenosylmethionine; Tritium | 1974 |
1-(2-(3, 4, 5, 6-Tetrahydropyridyl))-1, 3-pentadiene an N-methyltransferase inhibitor produced by actinomycetes.
Topics: Actinomyces; Alkadienes; Animals; Carbon Isotopes; Culture Media; In Vitro Techniques; Lung; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Methyltransferases; Pyridines; Rabbits; S-Adenosylmethionine; Spectrophotometry, Infrared; Tritium | 1974 |
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa].
Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting | 1972 |
N-methylation of dopamine to epinine in brain tissue using N-methyltetrahydrofolic acid as the methyl donor.
Topics: Animals; Brain; Carbon Isotopes; Coenzymes; Dopamine; Folic Acid; In Vitro Techniques; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1972 |
A dimethyltryptamine-forming enzyme in human blood.
Topics: Adolescent; Adult; Alcoholism; Blood Platelets; Blood Proteins; Carbon Isotopes; Depression; Erythrocytes; Female; Hallucinogens; Humans; Male; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Psychotic Disorders; Renal Dialysis; S-Adenosylmethionine; Schizophrenia; Tryptamines | 1973 |
A possible mechanism for the antischizophrenic action of chlorpromazine: inhibition of the formation of dimethyltryptamine by chlorpromazine metabolites.
Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Hallucinogens; Humans; Imipramine; In Vitro Techniques; Indoles; Lung; Mass Spectrometry; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Schizophrenia; Serotonin; Solvents; Tetrahydrofolates; Time Factors; Tryptamines | 1974 |
Evidence for the absence of amine-N-methylation and O-methylation in indolethylamines with methyltetrahydrofolic acid-dependent N-methyltransferase.
Topics: Animals; Brain; Carbon Radioisotopes; Chromatography, Thin Layer; Hallucinogens; In Vitro Techniques; Lung; Mass Spectrometry; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; Rats; S-Adenosylmethionine; Serotonin; Tetrahydrofolates; Tryptamines | 1974 |
Methylated messenger RNA synthesis in vitro by purified reovirus.
Topics: Chromatography, DEAE-Cellulose; Culture Media; DNA-Directed RNA Polymerases; Kinetics; L Cells; Methylation; Oligonucleotides; Phosphorus Radioisotopes; Reoviridae; RNA, Messenger; S-Adenosylmethionine; Stimulation, Chemical; Tritium; tRNA Methyltransferases; Valine | 1974 |
The biosynthesis of 5-methoxy-N,N-dimethyltryptamine in vitro.
Topics: Animals; Bufotenin; Chickens; Humans; Lung; Methoxydimethyltryptamines; Methylation; Methyltransferases; Organ Specificity; Rabbits; Rats; S-Adenosylmethionine; Tryptamines | 1974 |
Transmethylation of sterols in aerobically adapting Saccharomyces cerevisiae.
Topics: Adaptation, Physiological; Aerobiosis; Anaerobiosis; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Galactose; Glucose; Methionine; Methylation; Oxygen; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sterols; Vitamin D | 1972 |
Cell-free enzymic esterification of 5-carboxymethyluridine residues in bulk yeast transfer RNA.
Topics: Alkaline Phosphatase; Ammonium Sulfate; Carbon Isotopes; Carboxylic Acids; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Electrophoresis; Escherichia coli; Esters; Hydrolysis; Methylation; Plants; Ribonucleases; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Species Specificity; Subcellular Fractions; Triticum; Uridine | 1972 |
Methylation of purified transfer RNA preparations by extracts derived from rat kidney and kidney tumours.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Chemical Precipitation; Enzyme Activation; Escherichia coli; Formates; Glutamates; Kidney; Kidney Neoplasms; Magnesium; Methionine; Methylation; Methyltransferases; Putrescine; Quaternary Ammonium Compounds; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spermidine | 1972 |
Biosynthesis of mescaline and N-acetylmescaline by mammalian liver.
Topics: Acetamides; Acylation; Animals; Carbon Isotopes; Chromatography, Thin Layer; In Vitro Techniques; Liver; Mescaline; Methyl Ethers; Methylation; Rats; S-Adenosylmethionine | 1972 |
Deficiency of the DNA of Micrococcus radiodurans in methyladenine and methylcytosine.
Topics: Adenine Nucleotides; Carbon Isotopes; Cytosine Nucleotides; DNA, Bacterial; Escherichia coli; Methionine; Methylation; Methyltransferases; Micrococcus; RNA, Bacterial; S-Adenosylmethionine; Thymine Nucleotides; Tritium | 1972 |
DNA modification methylase activity of Escherichia coli restriction endonucleases K and P.
Topics: Chromatography, DEAE-Cellulose; Coliphages; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Endonucleases; Escherichia coli; Methylation; Methyltransferases; Phosphorus Isotopes; S-Adenosylmethionine; Tritium | 1972 |
Changes in tRNA methylase activity of rat kidney following administration of the carcinogen, dimethylnitrosamine.
Topics: Animals; Carbon Isotopes; Carcinogens; Escherichia coli; Female; Kidney; Kidney Neoplasms; Methylation; Methyltransferases; Nitrosamines; Protein Deficiency; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Time Factors | 1972 |
Partial purification of a tumor tRNA-guanine methyltransferase.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Escherichia coli; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Methylation; Methyltransferases; Mice; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1972 |
Differences in the methylation of transfer ribonucleic acid in vitro by the mitochondrial and cytoplasmic transfer ribonucleic acid methylases of HeLa cells.
Topics: Adenine Nucleotides; Autoradiography; Carbon Isotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Cytoplasm; Escherichia coli; Guanine Nucleotides; HeLa Cells; Methylation; Methyltransferases; Mitochondria; Nucleotides; Oligonucleotides; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; S-Adenosylmethionine; Tritium | 1973 |
Properties of metK mutants of Escherichia coli K-12.
Topics: Carbon Isotopes; Cell-Free System; Chromatography, Paper; Coliphages; Culture Media; Cystathionine; DNA, Bacterial; Escherichia coli; Fatty Acids; Genes; Hydro-Lyases; L-Serine Dehydratase; Leucine; Methionine; Methylation; Mutation; S-Adenosylmethionine; Sulfur Isotopes; Toluene; Transferases; Vibration | 1973 |
Formation in vitro of 1-methylguanine in 23-s RNA from Escherichia coli. The effects of spermidine and two proteins.
Topics: Bacterial Proteins; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Chromatography, Paper; Enzyme Activation; Enzymes; Escherichia coli; Genetics, Microbial; Guanine Nucleotides; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Methyltransferases; Mutation; Ribosomes; RNA, Bacterial; RNA, Ribosomal; S-Adenosylmethionine; Spermidine; Tromethamine | 1973 |
Methyltetrahydrofolic acid mediates N- and O-methylation of biogenic amines.
Topics: Animals; Biogenic Amines; Brain; Carbon Isotopes; Chickens; Coenzymes; Female; Folic Acid; Hallucinogens; Liver; Lung; Male; Methylamines; Methylation; Methyltransferases; Myocardium; Octopamine; Phenylethanolamine N-Methyltransferase; S-Adenosylmethionine; Serotonin; Tetrahydrofolates; Tryptamines; Tyramine | 1973 |
Function of N2 methylguanine in phenylalanine transfer RNA.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine | 1973 |
S-adenosylmethionine metabolism by members of the genus Candida.
Topics: Candida; Candida albicans; Carbon Radioisotopes; Cell-Free System; Chromatography; Culture Media; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1973 |
Escherichia coli formylmethionine tRNA: methylation of specific guanine and adenine residues catalyzed by HeLa cells tRNA methylases and the effect of these methylations on its biological properties.
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Escherichia coli; HeLa Cells; Humans; Methionine; Methylation; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Ribonucleases; Ribonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Tritium; tRNA Methyltransferases | 1974 |
Modified nucleosides in undermethylated phenylalanine transfer RNA from Escherichia coli.
Topics: Adenosine; Amino Acyl-tRNA Synthetases; Borohydrides; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Methylation; Methyltransferases; Phenylalanine; Ribonucleosides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Tritium | 1974 |
Enzymatic-isotopic method for octopamine at the picogram level.
Topics: Animals; Brain; Brain Chemistry; Ethanolamines; Evaluation Studies as Topic; Female; Guinea Pigs; Humans; Hypothalamus; Male; Methods; Methylation; Octopamine; Phenylethanolamine N-Methyltransferase; Pineal Gland; Pregnancy; Rats; S-Adenosylmethionine; Species Specificity; Spinal Cord; Tritium | 1974 |
Isolation, purification, and methylation of undermethylated tRNA Phe from an RC rel mutant of Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Evaluation Studies as Topic; Leucine; Methods; Methylation; Mutation; Phenylalanine; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; tRNA Methyltransferases; Tyrosine | 1974 |
Methylation of Escherichia coli transfer ribonucleic acids by adenylate residue-specific transfer ribonucleic acid methylase from rat liver.
Topics: Adenine Nucleotides; Amino Acids; Animals; Base Sequence; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Female; Hydrogen-Ion Concentration; Liver; Methylation; Methyltransferases; Nucleotides; Oligonucleotides; Rats; Ribonucleases; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship | 1974 |
A base-pairing hypothesis for t-RNA methylation.
Topics: Base Sequence; Binding Sites; Escherichia coli; Methylation; Nucleic Acid Conformation; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Structure-Activity Relationship; tRNA Methyltransferases | 1974 |
Acceptor activity of hypermethylated E. coli tRNAf-Met.
Topics: Amino Acyl-tRNA Synthetases; Base Sequence; Carbon Radioisotopes; Chromatography, Thin Layer; Escherichia coli; Formates; Isotope Labeling; Methionine; Methylation; Nucleic Acid Conformation; Oligonucleotides; Ribonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
Methylation of newly synthesized viral messenger RNA by an enzyme in vaccinia virus.
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; DNA, Viral; Escherichia coli; Methylation; Nucleotides; RNA, Messenger; RNA, Transfer; RNA, Viral; S-Adenosylmethionine; Saccharomyces cerevisiae; Tritium; tRNA Methyltransferases; Vaccinia virus | 1974 |
Methylation of yeast tRNA Asp by enzymes from cytoplasm, chloroplasts and mitochondria of phaseolus vulgaris.
Topics: Aspartic Acid; Base Sequence; Carbon Radioisotopes; Chloroplasts; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cytoplasm; Electrophoresis, Paper; Methylation; Mitochondria; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Plants; Ribonucleases; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; tRNA Methyltransferases; Urea | 1974 |
Isolation and in vitro restriction of unmethylated DNA from Escherichia coli K.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Gel; DNA Replication; DNA, Bacterial; Endonucleases; Escherichia coli; Isotope Labeling; Mathematics; Methionine; Methylation; Methyltransferases; Molecular Weight; Mutation; Nitrogen Isotopes; S-Adenosylmethionine; Temperature; Thymine; Tritium | 1974 |
Enzymatic-isotopic micromethods for the measurement of biogenic amines in brain tissue and body fluids.
Topics: Biogenic Amines; Blood Platelets; Brain Chemistry; Dopamine; Histamine; Humans; Hypothalamus; Limbic System; Methylation; Methyltransferases; Microchemistry; Norepinephrine; Octopamine; Phenethylamines; S-Adenosylmethionine; Serotonin; Tritium; Tryptamines | 1974 |
A protein-bound phosphorylated product as an intermediate in the biosynthesis of O-methyl glycerol by Mycobacterium tuberculosis.
Topics: Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Cyclization; Ethers; Glycerophosphates; Hydrogen-Ion Concentration; Hydrolysis; Methylation; Mycobacterium tuberculosis; Phosphoric Acids; Phosphotransferases; Protein Binding; S-Adenosylmethionine | 1972 |
Pancreas acinar cell differentiation. VII. Autoradiographic demonstration of intracellular radioactivity with with S-adenosyl-L-(C 3 H 3 ) methionine.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Nucleolus; Cell Nucleus; Culture Media; Cytoplasm; Methylation; Microscopy, Electron; Organ Culture Techniques; Pancreas; Rats; RNA, Ribosomal; S-Adenosylmethionine; Tritium | 1972 |
The metabolism of terbutaline in vitro by rat and human liver O-methyltransferases and monoamine oxidases.
Topics: Amino Alcohols; Animals; Butylamines; Carbon Isotopes; Electrophoresis, Paper; Epinephrine; In Vitro Techniques; Isoproterenol; Liver; Male; Metaproterenol; Methylation; Methyltransferases; Mitochondria, Liver; Monoamine Oxidase; Rats; Resorcinols; S-Adenosylmethionine; Tritium | 1972 |
[SAM-dependent transmethylation in hepatopathies of the aged].
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Creatine Kinase; Female; Humans; L-Lactate Dehydrogenase; Lipoproteins; Liver Diseases; Liver Function Tests; Male; Methylation; Middle Aged; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1972 |
Formation of phenylethanolamine N-methyl transferase complexes as an intermediate of the methylation of norepinephrine.
Topics: Animals; Carbon Isotopes; In Vitro Techniques; Kinetics; Methylation; Methyltransferases; Micropore Filters; Norepinephrine; Phenylethanolamine N-Methyltransferase; Rats; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1972 |
[Demonstration of the p-O-methylation of the catecholamine metabolite, protocatechuic acid, in isolated, perfused rat liver].
Topics: Animals; Benzoates; Carbon Isotopes; Catecholamines; Chromatography; Chromatography, Thin Layer; Hepatectomy; Liver; Male; Methods; Methylation; Perfusion; Rats; S-Adenosylmethionine | 1972 |
Enzymatic O-methylation of N-hydroxyxanthines by a rat kidney enzyme.
Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Drug Stability; Hot Temperature; Kidney; Liver; Methyl Ethers; Methylation; Methyltransferases; Radiation Effects; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Xanthines | 1972 |
Enzymatic methylation of glycine using a cell free supernatant from rat liver.
Topics: Animals; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Glycine; In Vitro Techniques; Liver; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Sarcosine | 1972 |
[Studies on vitamin B 12 -dependent reactions in Ascaris suum].
Topics: Animals; Ascaris; Cobamides; Coenzyme A; Female; Isomerases; Ligands; Malonates; Methylation; Methyltransferases; Ovary; RNA; RNA, Transfer; S-Adenosylmethionine; Vitamin B 12 | 1972 |
The enzymatic formation of 3,4-di-O-methylated dopamine metabolites by mammalian tissues.
Topics: Acetylation; Ammonium Sulfate; Animals; Biotransformation; Brain; Brain Stem; Carbon Radioisotopes; Caudate Nucleus; Cerebellum; Dialysis; Dopamine; Erythrocytes; Female; Humans; In Vitro Techniques; Infant, Newborn; Liver; Male; Mass Spectrometry; Methylation; Methyltransferases; Microsomes, Liver; Phenethylamines; Phenols; Pregnancy; Rats; S-Adenosylmethionine | 1972 |
Biosynthesis of branched chain deoxysugars. V. Biosynthesis of C-methyl branch by transmethylation from S-adenosylmethionine to cytidine diphosphate 4-keto-6-deoxy-D-glucose.
Topics: Azotobacter; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosine Nucleotides; Glucose; Methylation; Nucleoside Diphosphate Sugars; S-Adenosylmethionine; Tritium | 1973 |
Differentiation of chick embryo cerebral hemispheres. 3. Incorporation of ( 3 H-methyl)methionine into 29 S, 18 S and 4 S RNAs.
Topics: Age Factors; Animals; Brain; Cell Differentiation; Chick Embryo; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Time Factors; Tritium; Uridine | 1973 |
Protein methylation by cerebral tissue.
Topics: Acetone; Amino Acids; Ammonium Sulfate; Animals; Arginine; Brain; Carbon Isotopes; Cattle; Chromatography, DEAE-Cellulose; Cytoplasm; Dialysis; Histones; Lysine; Methylation; Nerve Tissue Proteins; Powders; Proteins; Rats; S-Adenosylmethionine; Time Factors | 1973 |
Evidence for a methylated protein intermediate in pituitary methanol formation.
Topics: Animals; Borates; Carbon Isotopes; Hydrogen-Ion Concentration; Methanol; Methylation; Methyltransferases; Pituitary Gland; Proteins; S-Adenosylmethionine | 1973 |
The periodic synthesis of S-adenosylmethionine: protein methyltransferases during the HeLa S-3 cell cycle.
Topics: Amino Acids; Arginine; Carbon Isotopes; Cycloheximide; Cytarabine; Dactinomycin; DNA Replication; DNA, Neoplasm; HeLa Cells; Histones; Humans; Kinetics; Lysine; Methionine; Methylation; Methyltransferases; Mitosis; Neoplasm Proteins; S-Adenosylmethionine; Thymidine | 1973 |
[Biological transmethylations].
Topics: Choline; Creatine; Histamine; Methylation; S-Adenosylmethionine; Tyrosine | 1973 |
[Incidence of catechol-O-methyltransferase in human erythrocytes].
Topics: Catechol O-Methyltransferase; Catecholamines; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Erythrocytes; Humans; Magnesium; Methylation; Methyltransferases; S-Adenosylmethionine | 1973 |
The activity of dopamine-beta-hydroxylase and methionine-activating enzyme in blood of schizophrenic patients.
Topics: Adenosine Triphosphate; Catecholamines; Chronic Disease; Dopamine beta-Hydroxylase; Erythrocytes; Humans; Hydroxylation; Incubators; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia; Transferases; Tritium | 1973 |
Dopamine-derived tetrahydroisoquinoline alkaloids--inhibitors of neuroamine metabolism.
Topics: Alkaloids; Amines; Animals; Carbon Radioisotopes; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, Gas; Dopamine; Dopamine Antagonists; In Vitro Techniques; Isoquinolines; Kinetics; Liver; Male; Methylation; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; S-Adenosylmethionine; Tritium | 1973 |
Stereochemistry of methyl group insertion in corrinoid biosynthesis. Determination of carbon isotope chirality by 13C nuclear magnetic resonance.
Topics: Carbon Isotopes; Magnetic Resonance Spectroscopy; Methylation; Porphyrins; Propionibacterium; S-Adenosylmethionine; Stereoisomerism; Vitamin B 12 | 1973 |
Catechol O-methyltransferase. 2. In vitro inhibition by substituted 8-hydroxyquinolines.
Topics: Animals; Benzoates; Binding Sites; Carbon Isotopes; Catechol O-Methyltransferase Inhibitors; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Iodine; Kinetics; Liver; Magnesium; Male; Methylation; Methyltransferases; Osmolar Concentration; Protein Binding; Quinolines; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1973 |
Catechol O-methyltransferase. 3. Mechanism of pyridoxal 5'-phosphate inhibition.
Topics: Animals; Benzoates; Carbon Isotopes; Catechol O-Methyltransferase Inhibitors; Chemical Phenomena; Chemistry; Isoquinolines; Kinetics; Liver; Magnesium; Male; Methylation; Methyltransferases; Norepinephrine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 1973 |
Methylation of parental and progeny DNA strands in Physarum polycephalum.
Topics: Carbon Isotopes; Cell Division; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine; Deoxycytidine; DNA; Drug Stability; Isotope Labeling; Methylation; Mitosis; Myxomycetes; Phosphorus Isotopes; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
Evidence for the methylation of apomorphine by catechol-O-methyl-transferase in vivo and in vitro.
Topics: Alcohols; Animals; Apomorphine; Brain; Carbon Radioisotopes; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, Paper; Cycloheptanes; Drug Synergism; Humans; Kinetics; Liver; Male; Methylation; Pyrogallol; Quinolines; Rats; S-Adenosylmethionine; Stereotyped Behavior | 1973 |
Deoxyribonucleic acid methylation and development in Caulobacter bacteroides.
Topics: Adenine; Bacteria; Carbon Radioisotopes; Cell-Free System; Chromatography, Thin Layer; Cytosine; DNA, Bacterial; Hydrolysis; Methylation; Methyltransferases; S-Adenosylmethionine | 1973 |
Tetrahydroisoquinolines derived from noradrenaline-aldehyde condensations. Pyrogallol-sensitive O-methylation in rat homogenates.
Topics: Aldehydes; Animals; Brain; Catechol O-Methyltransferase Inhibitors; Catechols; Isoquinolines; Liver; Male; Methylation; Norepinephrine; Pyrogallol; Quinones; Rats; S-Adenosylmethionine; Tritium | 1973 |
Methylation of exogenous 3,4-dihydroxyphenylalanine (,dopa)--effects on methyl group metabolism.
Topics: Animals; Brain; Carbon Radioisotopes; Dihydroxyphenylalanine; In Vitro Techniques; Kidney; Liver; Male; Methionine; Methylation; Muscles; Rats; RNA, Transfer; S-Adenosylmethionine; Time Factors; Yeasts | 1973 |
Inhibition of catechol-O-methyl transferase by catechols and polyphenols.
Topics: Animals; Benserazide; Brain; Catechol O-Methyltransferase Inhibitors; Catechols; Dihydroxyphenylalanine; Kinetics; Liver; Male; Methylation; Myocardium; Norepinephrine; Normetanephrine; Phenols; Polymers; Pyrogallol; Rats; S-Adenosylmethionine; Tritium | 1973 |
Enzymatic studies on the metabolism of the tetrahydrofurfuryl mercaptan moiety of thiamine tetrahydrofurfuryl disulfide. I. Microsomal S-transmethylase.
Topics: Animals; Ascorbic Acid; Benzenesulfonates; Carbon Radioisotopes; Chlorides; Chloromercuribenzoates; Chromatography; Cysteine; Disulfides; Furans; Glutathione; Intestine, Small; Kidney; Liver; Male; Mercury; Methionine; Methylation; Methyltransferases; Microsomes; Organometallic Compounds; Rats; S-Adenosylmethionine; Spectrophotometry, Infrared; Sulfhydryl Compounds; Thiamine; Tritium | 1973 |
Effect of trypsin on DNA methylation in isolated nuclei from developing sea urchin embryos.
Topics: Animals; Cattle; Cell Nucleus; Chromatography, Paper; Cytosine; Deoxyribonucleases; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Activation; Methylation; Methyltransferases; Pancreas; Pronase; Ribonucleases; RNA; S-Adenosylmethionine; Sea Urchins; Spectrophotometry, Ultraviolet; Thymine; Time Factors; Tritium; Trypsin | 1973 |
DNA methylation in isolated nuclei: old and new DNAs are methylated.
Topics: Aminopterin; Animals; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Paper; DNA; Fibroblasts; Kinetics; L Cells; Methionine; Methylation; Mice; S-Adenosylmethionine; Thymidine; Tritium | 1973 |
Studies in vivo and in vitro on the methylation of phosphatidyl-N,N-dimethylethanolamine to phosphatidylcholine in rat liver.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Endoplasmic Reticulum; Isotope Labeling; Liver; Methylation; Methyltransferases; Organ Specificity; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Time Factors; Tritium | 1973 |
Amphetamine in human plasma: a sensitive and specific enzymatic assay.
Topics: Amphetamine; Animals; Clinical Enzyme Tests; Humans; Lung; Methods; Methylation; Methyltransferases; Rabbits; S-Adenosylmethionine; Substance-Related Disorders; Tritium | 1974 |
Relation between the hepatic action of drugs and the synthesis of subcellular structures.
Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Choline; Dactinomycin; Deficiency Diseases; Diet; Drug Interactions; In Vitro Techniques; Liver; Male; Methionine; Methylation; Methyltransferases; Microsomes, Liver; Phenobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats; S-Adenosylmethionine; Subcellular Fractions | 1974 |
Correlation between synthesis and methylation of DNA in HeLa cells.
Topics: Carbon Radioisotopes; Cell Division; Cell Nucleus; Chromatography, Paper; Cytosine; DNA, Neoplasm; HeLa Cells; Isotope Labeling; Methionine; Methylation; S-Adenosylmethionine; Thymidine; Time Factors; Tritium | 1974 |
In vivo and in vitro utilization of labeled precursors for choline synthesis in mature Japanese quail as compared to rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Chickens; Choline; Coturnix; Ethanolamines; Female; In Vitro Techniques; Liver; Methionine; Methylamines; Methylation; Methyltransferases; Nutritional Requirements; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine; Serine; Species Specificity | 1974 |
N-methylation of indolealkylamines in the brain with a new methyl donor.
Topics: Amines; Ammonium Sulfate; Animals; Brain; Carbon Radioisotopes; Catechol O-Methyltransferase; Catecholamines; Catechols; Centrifugation, Density Gradient; Chromatography, Gel; Hydrogen-Ion Concentration; Indoles; Kinetics; Methylation; Methyltransferases; Nitrogen; Oxygen Consumption; Phenethylamines; Rats; S-Adenosylmethionine; Serotonin; Sucrose; Tetrahydrofolates; Tryptamines | 1974 |
N-methyltetrahydrofolic acid: the physiological methyl donor in indoleamine N- and O-methylation.
Topics: Animals; Biogenic Amines; Brain; Carbon Radioisotopes; Chickens; Dialysis; Female; Hallucinogens; In Vitro Techniques; Kinetics; Lung; Male; Methylation; Methyltransferases; Myocardium; Nitrogen; Organ Specificity; Oxygen Consumption; Rabbits; Rats; S-Adenosylmethionine; Serotonin; Species Specificity; Tetrahydrofolates; Tryptamines; Tyramine | 1974 |
Effects of aromatic aldehydes on O-methylation of dopamine and norepinephrine in vitro.
Topics: Aldehydes; Animals; Benzaldehydes; Carbon Radioisotopes; Catechol O-Methyltransferase; Chemical Phenomena; Chemistry; Chromatography; Dopamine; Isoquinolines; Kinetics; Liver; Methylation; Norepinephrine; Normetanephrine; Pyridines; Rats; S-Adenosylmethionine; Schiff Bases; Spectrophotometry, Ultraviolet; Tritium; Tyramine | 1974 |
Methylation of histones by chemicals and embryonic liver enzymes: their ability to repress in vitro RNA synthesis.
Topics: Amino Acids; Animals; Arginine; Carbon Radioisotopes; Cattle; DNA; DNA-Directed RNA Polymerases; Electrophoresis, Paper; Enzyme Repression; Female; Fetus; Histones; Kinetics; Liver; Male; Methylation; Methyltransferases; Pregnancy; Rats; S-Adenosylmethionine; Salmon; Spermatozoa; Thymus Gland; Time Factors; Tritium; Uracil Nucleotides | 1974 |
The preparation of soluble DNA methylase from normal and regenerating rat liver.
Topics: Animals; Cattle; Cell Nucleus; Chromatography; Dactinomycin; DNA; Escherichia coli; Female; Fluorenes; Hepatectomy; Liver; Liver Regeneration; Methods; Methylation; Methyltransferases; Phenylalanine; Rats; S-Adenosylmethionine; Time Factors; Transferases; Tritium | 1971 |
Mechanism of action of rat liver DNA methylase. I. Interaction with double-stranded methyl-acceptor DNA.
Topics: Animals; Cytosine; DNA; DNA, Bacterial; Escherichia coli; Liver; Methylation; Methyltransferases; Molecular Weight; Protein Binding; Rats; S-Adenosylmethionine; Sodium Chloride; Temperature; Transferases; Tritium; Ultracentrifugation; Vibration | 1971 |
Methylation of DNA in ultraviolet-irradiated bacteria.
Topics: Adenine; Carbon Isotopes; Chromatography, Paper; Cytosine; Deoxyribonucleases; DNA; DNA, Bacterial; Escherichia coli; Methionine; Methylation; Methyltransferases; Nucleic Acid Denaturation; Pancreas; Radiation Effects; Ribonucleases; S-Adenosylmethionine; Time Factors; Tritium; Ultraviolet Rays; Uracil | 1971 |
Fragmented E. coli methionine tRNA f as methyl acceptor for rat liver tRNA methylase: alteration of the site of methylation by the conformational change of tRNA structure resulting from fragmentation.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Escherichia coli; Formates; Guanine; Liver; Methionine; Methylation; Methyltransferases; Nucleosides; Nucleotidyltransferases; Pancreas; Paper; Polynucleotides; Rats; Ribonucleases; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Transferases | 1971 |
In vitro O 2 '-methylation of sugars in E. coli RNA. 3. Methylation of E. coli transfer RNA by heterologous methylases in particulate-free extracts of wheat embryo.
Topics: Base Sequence; Carbon Isotopes; Cell-Free System; Embryo, Mammalian; Embryo, Nonmammalian; Escherichia coli; Methylation; Plants; Purines; Pyrimidines; Ribonucleotides; Ribose; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Seeds; Species Specificity; Triticum; Ultracentrifugation | 1969 |
The coding nature of valyl-transfer RNA binding to ribosomes during methionine starvation in E. coli 113-3.
Topics: Carbon Isotopes; Depression, Chemical; Escherichia coli; Genetic Code; Guanine Nucleotides; Liver; Methionine; Methylation; Methyltransferases; Mutation; Polynucleotides; Protein Binding; Ribosomes; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Stimulation, Chemical; Time Factors; Uracil Nucleotides; Valine | 1971 |
Control of gene function in bacteriophage Tr. 3. Preventing the shutoff of early enzyme synthesis.
Topics: Aminohydrolases; Carbon Isotopes; Cell-Free System; Coliphages; Cytosine Nucleotides; Escherichia coli; Genes; Genetics, Microbial; Glucosyltransferases; Lysogeny; Methylation; Muramidase; Mutation; Radiation Effects; S-Adenosylmethionine; Time Factors; Tritium; Ultraviolet Rays | 1971 |
Methylation of arginine and lysine residues of cerebral proteins.
Topics: Amino Acids; Animals; Arginine; Bacteria; Brain; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Enterococcus faecalis; Hydrolysis; Isomerism; Liver; Lysine; Methylation; Nerve Tissue Proteins; Proteins; Rats; S-Adenosylmethionine; Ureohydrolases | 1971 |
Interactions between estrogens and catechol amines. 3. Studies on the methylation of catechol estrogens, catechol amines and other catechols by the ctechol-O-methyltransferases of human liver.
Topics: Adult; Carbon Isotopes; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dopamine; Epinephrine; Estradiol; Estriol; Estrogens; Estrone; Humans; Kinetics; Liver; Magnesium; Male; Mandelic Acids; Methylation; Methyltransferases; Norepinephrine; S-Adenosylmethionine; Time Factors | 1972 |
Kinetic properties of a soluble catechol O-methyltransferase of human liver.
Topics: Allosteric Regulation; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, Paper; Cysteine; Drug Interactions; Estriol; Humans; Hydrogen-Ion Concentration; Hydroxysteroids; Isomerism; Kinetics; Liver; Magnesium; Methyl Ethers; Methylation; Methyltransferases; S-Adenosylmethionine; Spectrum Analysis; Temperature | 1972 |
[The p-O-methylation of the catecholamine metabolite protocatechuic aldehyde in isolated perfused rat liver].
Topics: Aldehydes; Animals; Carbon Isotopes; Catechols; Chromatography, Thin Layer; Flavoring Agents; Hydrazones; In Vitro Techniques; Liver; Male; Methylation; Nitrobenzenes; Perfusion; Rats; S-Adenosylmethionine | 1972 |
[Various effects of SAM dependent transmethylations in hepatology].
Topics: Adenosine; Biopsy; Chronic Disease; Fatty Liver; Hepatitis; Humans; Injections, Intraperitoneal; Lipid Metabolism; Liver Cirrhosis; Liver Diseases; Liver Glycogen; Methionine; Methylation; S-Adenosylmethionine | 1972 |
Identification of N,N-dimethyltryptamine as the product of an in vitro enzymic methylation.
Topics: Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Deuterium; Humans; Lung; Mass Spectrometry; Mathematics; Methods; Methylation; Methyltransferases; S-Adenosylmethionine; Tryptamines | 1972 |
Indoleamine-N-methyl transferase in human lung.
Topics: Adolescent; Adult; Amines; Ammonium Sulfate; Carbon Isotopes; Centrifugation; Chromatography, Gel; Chromatography, Thin Layer; Dialysis; Female; Humans; Indoles; Lung; Male; Methylation; Methyltransferases; Middle Aged; S-Adenosylmethionine; Serotonin; Structure-Activity Relationship; Tryptamines | 1972 |
Pancreas acinar cell differentiation. V. Significance of methyl groups in morphologic and enzymatic development.
Topics: Amylases; Animals; Choline; Chymotrypsin; Culture Media; Cysteine; Cystine; Lipase; Methionine; Methylation; Microscopy, Electron; Organ Culture Techniques; Pancreas; Rats; RNA, Transfer; S-Adenosylmethionine | 1972 |
Biosynthesis of Se-methylselenocysteine and S-methylcysteine in Astragalus bisculcatus. Origin of the selenomethyl and the thiomethyl groups.
Topics: Carbon Isotopes; Chromatography, Paper; Cystathionine; Cysteine; Methionine; Methylation; Plants; Radioisotopes; S-Adenosylmethionine; Selenium | 1972 |
RNA metabolism in HeLa cells at reduced temperature. II. Steps in the processing of transfer RNA.
Topics: Cell Fractionation; Cell Nucleus; Cell-Free System; Cytoplasm; Electrophoresis, Disc; HeLa Cells; Methionine; Methylation; Phosphorus Isotopes; RNA, Transfer; S-Adenosylmethionine; Temperature; Tritium; Uridine | 1972 |
Mutants of bacteriophage T2 gt with altered DNA methylase activity.
Topics: Chromatography, Affinity; Coliphages; DNA, Viral; Enzyme Induction; Hot Temperature; Methylation; Methyltransferases; Mutation; S-Adenosylmethionine; Tritium | 1972 |
Histone methylation during hepatic regeneration in rat.
Topics: Animals; Arginine; Carbon Isotopes; Cytoplasm; DNA; Hepatectomy; Histones; Kinetics; Liver; Liver Regeneration; Lysine; Male; Methylation; Methyltransferases; Orotic Acid; Proteins; Rats; RNA; S-Adenosylmethionine; Thymidine; Tritium | 1972 |
Protein methylation during the development of rat brain.
Topics: Animals; Animals, Newborn; Arginine; Brain; Carbon Isotopes; Carboxylic Acids; Cytoplasm; Ethanol; Fetus; Histones; Lysine; Methionine; Methylation; Methyltransferases; Nerve Tissue Proteins; Proteins; Rats; S-Adenosylmethionine; Solubility; Sulfuric Acids; Transferases; Tritium | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
The deoxyribonucleic acid modification enzyme of bacteriophage P1.
Topics: Ammonium Sulfate; Catalase; Centrifugation, Zonal; Chromatography, DEAE-Cellulose; Coliphages; Dialysis; DNA, Viral; Hydrogen-Ion Concentration; Hydrolysis; Methylation; Methyltransferases; Morpholines; Purines; S-Adenosylmethionine; Sulfonic Acids; Tritium | 1972 |
[Hypercholesterolemic action of S-adenosyl-methionine (SAM)].
Topics: Arteriosclerosis; Chemical Phenomena; Chemistry; Cholesterol; Fatty Acids, Unsaturated; Humans; Hypercholesterolemia; Kaolin; Methylation; Phospholipids; S-Adenosylmethionine | 1972 |
RNA synthesis in isolated rabbit-liver nuclei.
Topics: Animals; Carbon Isotopes; Cations, Monovalent; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; DNA-Directed RNA Polymerases; Liver; Magnesium; Male; Methylation; Nucleoproteins; Pronase; Rabbits; Ribonucleotides; RNA; S-Adenosylmethionine | 1972 |
Protein methylation.
Topics: Actins; Amino Acids; Animals; Arginine; Aspartic Acid; Autoanalysis; Carboxylic Acids; Cats; Cattle; Cell Wall; Chromatography, Paper; Cytochromes; Flagella; Glutamates; Histidine; Histones; Humans; Lysine; Methylation; Methyltransferases; Myosins; Ornithine; Ovalbumin; Proteins; Rabbits; Rats; Ribosomes; S-Adenosylmethionine | 1971 |
Transfer ribonucleic acid methylases during the germination of Neurospora crassa.
Topics: Adenine; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Culture Media; Guanine; Hydrolysis; Methylation; Methyltransferases; Neurospora; Phenols; RNA, Transfer; S-Adenosylmethionine; Spores; Spores, Fungal | 1971 |
Histone methylation. Partial purification of two histone-specific methyltransferases from rat thymus nuclei preferentially methylating histones F2a 1 and F3.
Topics: Acetone; Albumins; Amino Acids; Ammonium Sulfate; Animals; Arginine; Cell Nucleus; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytochromes; Electrophoresis; Hemoglobins; Histidine; Histones; Hydrogen-Ion Concentration; Kinetics; Lysine; Male; Methylation; Methyltransferases; Molecular Weight; Muramidase; Peptides; Protamines; Rats; Rats, Inbred Strains; Ribonucleases; S-Adenosylmethionine; Thymus Gland; Tritium | 1971 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.
Topics: Alkylation; Amino Acids; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Chromatography, Paper; Female; Formaldehyde; Histones; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Methionine; Methylation; Necrosis; Nitrosamines; Rats; S-Adenosylmethionine; Sulfonic Acids; Tritium | 1971 |
Enzymatic methylation of skeletal muscle contractile proteins.
Topics: Actins; Actomyosin; Animals; Animals, Newborn; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Histidine; Kinetics; Lysine; Methionine; Methylation; Muscle Proteins; Muscles; Myofibrils; Myosins; S-Adenosylmethionine; Sarcoplasmic Reticulum; Ultracentrifugation | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Enzymic methylation of L-ascorbic acid by catechol O-methyltransferase.
Topics: Ammonium Sulfate; Animals; Ascorbic Acid; Carbon Isotopes; Carbon Radioisotopes; Catechol O-Methyltransferase; Catechols; Chemical Precipitation; Chromatography, Gel; Chromatography, Paper; Edetic Acid; Enzyme Activation; Ethers; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Magnesium Sulfate; Methyl Ethers; Methylation; Methyltransferases; Rats; S-Adenosylmethionine | 1971 |
Transfer RNA methylases during sea urchin embryogenesis.
Topics: Acetates; Animals; Carbon Isotopes; Chemical Precipitation; Cytosine Nucleotides; Deoxyribonucleases; Ethanol; Female; Guanine; Hydrolysis; Methionine; Methylation; Methyltransferases; Ovum; Phenols; Potassium; Pronase; RNA, Transfer; S-Adenosylmethionine; Sea Urchins; Time Factors; Tritium; Uracil Nucleotides | 1971 |
Studies on the structural requirements of substrate protein for protein methylase II.
Topics: Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Colorimetry; Formates; Glycine max; Hot Temperature; Hydrolysis; Imides; Mercaptoethanol; Methylamines; Methylation; Methyltransferases; Oxidation-Reduction; Pancreas; Pronase; Proteins; Ribonucleases; S-Adenosylmethionine; Thymus Gland; Trypsin; Trypsin Inhibitors | 1971 |
Transfer ribonucleic acid methyltransferases during hormone-induced synthesis of phosvitin.
Topics: Adenine Nucleotides; Animals; Arginine; Carbon Isotopes; Chickens; Chromatography; Cytosine Nucleotides; Depression, Chemical; Diethylstilbestrol; Egg Yolk; Estradiol; Female; Guanine Nucleotides; Hydroxyapatites; Liver; Male; Methylation; Methyltransferases; Phosphoproteins; Phosphoric Acids; Protein Biosynthesis; RNA, Transfer; S-Adenosylmethionine; Stimulation, Chemical | 1971 |
Selective in vitro methylation of rat chromatin associated histone after partial hepatectomy.
Topics: Animals; Autoradiography; Chromatin; Electrophoresis, Disc; Hepatectomy; Histones; Liver Regeneration; Methylation; Rats; S-Adenosylmethionine; Tritium | 1971 |
Catechol O-methyltransferase. The para- and meta-O-methylations of noradrenaline.
Topics: Animals; Carbon Isotopes; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chlorides; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electrophoresis; Electrophoresis, Disc; Hydrogen-Ion Concentration; Isoenzymes; Isomerism; Kinetics; Liver; Magnesium; Methods; Methylation; Methyltransferases; Norepinephrine; Osmolar Concentration; Quaternary Ammonium Compounds; Rats; S-Adenosylmethionine; Solubility; Sulfates; Time Factors; Transferases | 1971 |
O-Methylation of noradrenaline and demethylation in rat blood.
Topics: Animals; Blood; Carbon Isotopes; Catechols; Chromatography, Paper; Dealkylation; Isomerism; Methylation; Methyltransferases; Norepinephrine; Quaternary Ammonium Compounds; Rats; S-Adenosylmethionine; Sulfates; Transferases; Tritium | 1971 |
Enzymic modification of chromosomal macromolecules. I. DNA and protein methylation in mouse tumour cell chromatin.
Topics: Amino Acids; Animals; Arginine; Ascitic Fluid; Catalysis; Cell Nucleus; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography; Chromatography, Paper; Chromosomes; Colorimetry; Cytosine; Deoxyribonucleases; DNA, Neoplasm; Drug Stability; Electrophoresis; Histidine; Histones; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Methylation; Methyltransferases; Mice; Neoplasm Proteins; Neoplasms, Experimental; S-Adenosylmethionine; Temperature; Time Factors; Transferases; Tritium | 1971 |
Inhibition of transmethylations of biogenic amines by S-adenosylhomocysteine. Enhancement of transmethylation by adenosylhomocysteinase.
Topics: Adrenal Glands; Animals; Brain; Carbon Isotopes; Catechols; Epinephrine; Homocysteine; Hydrolases; Indoles; Methylation; Methyltransferases; Nucleosides; Rabbits; Rats; S-Adenosylmethionine | 1971 |
Effect of serum on the synthesis of RNA and of DNA in the cultured lens epithelium of the chick embryo: initiation of lens fiber formation in vitro.
Topics: Adenosine Triphosphate; Animals; Blood; Cattle; Centrifugation, Density Gradient; Cesium; Chick Embryo; Chlorides; Culture Techniques; Dactinomycin; DNA; Electrophoresis; Epithelium; Female; Fetus; Lens, Crystalline; Methionine; Methylation; Nucleosides; RNA; RNA, Ribosomal; S-Adenosylmethionine; Stimulation, Chemical; Sucrose; Tritium | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XII mutational and non-mutational mechanism as subsets of a more general mechanism. Part A--Ethionine.
Topics: alpha-Fetoproteins; Animals; Carcinogens; DNA, Neoplasm; Embryo, Mammalian; Ethionine; Gene Expression Regulation; Humans; Methylation; Neoplasm Proteins; Neoplasms; S-Adenosylmethionine | 1984 |
Stoichiometric methylation of porcine adrenocorticotropin by protein carboxyl methyltransferase requires deamidation of asparagine 25. Evidence for methylation at the alpha-carboxyl group of atypical L-isoaspartyl residues.
Topics: Adrenocorticotropic Hormone; Animals; Asparagine; Cattle; Cerebral Cortex; Hydroxylamine; Hydroxylamines; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Substrate Specificity; Swine | 1984 |
HhaI methylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences.
Topics: Base Sequence; Deoxyribonucleases, Type II Site-Specific; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Haemophilus; Kinetics; Methylation; Methyltransferases; Nucleic Acid Conformation; Plasmids; S-Adenosylmethionine | 1984 |
Preferential cleavage by restriction endonuclease HinfIII.
Topics: Base Sequence; Deoxyribonucleases, Type III Site-Specific; DNA; DNA Restriction Enzymes; DNA, Bacterial; DNA, Superhelical; Methylation; Plasmids; S-Adenosylmethionine; Substrate Specificity | 1984 |
Decrease of noradrenaline O-methylation in rat brain induced by L-dopa. Reversal effect of S-adenosyl-L-methionine.
Topics: Animals; Brain; Levodopa; Male; Methoxyhydroxyphenylglycol; Methylation; Norepinephrine; Rats; S-Adenosylmethionine | 1980 |
The methyl-folate trap and the supply of S-adenosylomethionine.
Topics: Brain; Brain Diseases; Folic Acid; Methionine; Methylation; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1981 |
Methylation and mood.
Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency | 1984 |
Inhibition of nucleic acid methylation by cordycepin. In vivo synthesis of S-3'-DEOXYADENOSYLMETHIONINE BY WI-L2 human lymphoblasts.
Topics: Adenosine Triphosphate; Cell Line; Deoxyadenosines; DNA; Humans; Methionine Adenosyltransferase; Methylation; RNA; S-Adenosylmethionine; Substrate Specificity; Transferases | 1980 |
The methylation in vitro of myelin basic protein by arginine methylase from mouse spinal cord.
Topics: Animals; Methionine; Methylation; Mice; Myelin Basic Protein; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Spinal Cord | 1980 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Concomitant methylation and synthesis in vitro of Semliki Forest virus (SFV) ss RNAs by a fraction from infected cells.
Topics: Animals; Cell Line; Cricetinae; Kinetics; Methylation; Methyltransferases; RNA; RNA Caps; RNA, Viral; S-Adenosylmethionine; Semliki forest virus | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Methyl group transfer from exogenous S-adenosylmethionine on to plasma-membrane phospholipids without cellular uptake in isolated hepatocytes.
Topics: Animals; Cell Membrane; In Vitro Techniques; Liver; Methylation; Nucleotidases; Phospholipids; Rats; RNA; S-Adenosylmethionine; Subcellular Fractions | 1982 |
Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA.
Topics: Chromatography, High Pressure Liquid; HeLa Cells; Homocysteine; Humans; Interferons; Methylation; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1983 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Transmethylation, transsulfuration, and aminopropylation reactions of S-adenosyl-L-methionine in vivo.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Creatinine; DNA; Liver; Male; Methylation; Proteins; Rats; Rats, Inbred Strains; RNA; S-Adenosylmethionine; Sulfur Radioisotopes | 1984 |
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187.
Topics: Adenine; Adenosine; Antibodies, Anti-Idiotypic; Calcimycin; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1984 |
Enzymatic methylation and demethylation of protein-bound lysine residues.
Topics: Amino Acid Sequence; Animals; Carbon Radioisotopes; Histone-Lysine N-Methyltransferase; Kinetics; Methylation; Neurospora crassa; Peptide Fragments; Protein Methyltransferases; Radioisotope Dilution Technique; S-Adenosylmethionine; Substrate Specificity | 1984 |
Regulation of beta-adrenergic receptors by phospholipid methylation.
Topics: Adenylyl Cyclases; Animals; Anura; Cell Membrane; Cyclic AMP; Humans; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipids; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; S-Adenosylmethionine | 1980 |
Effect of phospholipid methylation on beta-adrenergic receptors in the normal and hypertrophied rat myocardium.
Topics: Animals; Aorta, Abdominal; Binding Sites; Cardiomegaly; Constriction; Dihydroalprenolol; Male; Methylation; Phospholipids; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; S-Adenosylmethionine; Time Factors | 1980 |
Modification of calmodulin function by enzymatic carboxylic methylation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Brain; Calcium-Binding Proteins; Calmodulin; Cattle; Enzyme Activation; Kinetics; Methylation; S-Adenosylmethionine | 1981 |
Cleavage and methylation of DNA by the restriction endonuclease HinfIII isolated from Haemophilus influenzae Rf.
Topics: Bacteriophage lambda; DNA Restriction Enzymes; DNA, Superhelical; DNA, Viral; Electrophoresis, Agar Gel; Haemophilus influenzae; Methylation; Protein Binding; S-Adenosylmethionine | 1980 |
Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractions.
Topics: Arginine; Butyrates; Cell Nucleus; HeLa Cells; Histones; Humans; Lysine; Methylation; Nucleoproteins; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; S-Adenosylmethionine | 1981 |
Effects of a methyl-deficient diet on rat liver phosphatidylcholine biosynthesis.
Topics: Animals; Choline Deficiency; Diacylglycerol Cholinephosphotransferase; Diet; Female; Liver; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Membrane modification differentially affects the binding of the lactogenic hormones human growth hormone and ovine prolactin.
Topics: Animals; Cell Membrane; Cells, Cultured; Female; Growth Hormone; Humans; Lactation; Mammary Glands, Animal; Membrane Lipids; Methylation; Mice; Phosphatidylcholines; Pregnancy; Prolactin; Receptors, Cell Surface; S-Adenosylmethionine | 1981 |
Enzymatic methylation of microsomal metabolites of benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Male; Methylation; Microsomes, Liver; Rats; Rats, Inbred F344; S-Adenosylmethionine; Substrate Specificity | 1981 |
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline | 1982 |
Accumulation of spliced avian retrovirus mRNA is inhibited in S-adenosylmethionine-depleted chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cells, Cultured; Chick Embryo; Cycloleucine; Fibroblasts; Kinetics; Methylation; Protein Precursors; RNA Splicing; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Viral Proteins | 1982 |
Isolation and characterization of bacteriophage T3 mutants sensitive to restriction by EcoRI.
Topics: Base Sequence; Chromosome Mapping; DNA Restriction Enzymes; DNA, Viral; Methylation; Mutation; S-Adenosylmethionine; Substrate Specificity; T-Phages | 1982 |
Phospholipid methylation in canine cardiac membranes. Relations to beta-adrenergic receptors and digitalis receptors.
Topics: Animals; Dogs; Hydrogen-Ion Concentration; Membranes; Methylation; Myocardium; Phospholipids; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Drug; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase | 1983 |
Phospholipid methylation increases [3H]diazepam and [3H]GABA binding in membrane preparations of rat cerebellum.
Topics: Animals; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Kinetics; Methylation; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; S-Adenosylmethionine; Synaptic Membranes | 1983 |
Molecular mechanisms in the antiepileptic action of benzodiazepines.
Topics: Animals; Anticonvulsants; Benzodiazepines; Biomechanical Phenomena; Cell Membrane; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Lipids; Methylation; Phospholipids; Rats; Receptors, Cell Surface; Receptors, GABA-A; S-Adenosylmethionine; Synapses | 1983 |
Sites of methyl esterification on the aspartate receptor involved in bacterial chemotaxis.
Topics: Chemotaxis; Chromatography, High Pressure Liquid; DNA; Escherichia coli; Methylation; Plasmids; Receptors, Amino Acid; Receptors, Cell Surface; S-Adenosylmethionine; Salmonella typhimurium; Trypsin | 1983 |
Inhibition of rat brain microsomal Na+,K+-ATPase by S-adenosylmethionine.
Topics: Animals; Brain; Homocysteine; Lipid Metabolism; Methylation; Microsomes; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Tubercidin | 1984 |
Effect of Friend virus infection on the biosynthetic enzymes of phosphatidylcholine biosynthesis in spleen microsomes.
Topics: Animals; Diacylglycerol Cholinephosphotransferase; Friend murine leukemia virus; Leukemia, Experimental; Male; Methylation; Mice; Mice, Inbred BALB C; Microsomes; Phosphatidylcholines; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1984 |
45Ca2+ uptake and phospholipid methylation in isolated rat liver microsomes.
Topics: Animals; Calcium; Calcium Radioisotopes; Epinephrine; Glucagon; Insulin; Male; Methylation; Microsomes; Microsomes, Liver; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Insulin stimulation of phospholipid methylation in isolated rat adipocyte plasma membranes.
Topics: Adipose Tissue; Animals; Cell Membrane; Insulin; Kinetics; Male; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Substrate Specificity | 1984 |
Methylated proteins and amino acids in the ribosomes of Saccharomyces cerevisiae.
Topics: Amino Acids; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Methylation; Ribosomal Proteins; Ribosomes; S-Adenosylmethionine; Saccharomyces cerevisiae | 1984 |
S-adenosylmethionine: protein-carboxyl O-methyltransferase (protein methylase II).
Topics: Amino Acids; Animals; Brain; Carbon Radioisotopes; Cattle; Chromatography, Affinity; Chromatography, Ion Exchange; Drug Stability; Erythrocytes; Humans; Kinetics; Methylation; Molecular Weight; Protein Methyltransferases; Protein O-Methyltransferase; Radioisotope Dilution Technique; S-Adenosylmethionine; Thymus Gland | 1984 |
The protein carboxylmethyltransferase involved in Escherichia coli and Salmonella typhimurium chemotaxis.
Topics: Cell Membrane; Chemotaxis; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Radioisotope Dilution Technique; S-Adenosylmethionine; Salmonella typhimurium; Species Specificity; Tritium | 1984 |
Acetylation and methylation patterns of core histones are modified after heat or arsenite treatment of Drosophila tissue culture cells.
Topics: Acetates; Acetylation; Animals; Arsenic; Arsenites; Cells, Cultured; Drosophila melanogaster; Histones; Hot Temperature; Kinetics; Methylation; S-Adenosylmethionine; Tritium | 1983 |
Chemotaxis of Pseudomonas aeruginosa: involvement of methylation.
Topics: Aminoisobutyric Acids; Arginine; Bacterial Proteins; Chemotaxis; Kinetics; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Methyltransferases; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine | 1983 |
Protein and lipid methylation by methionine and S-adenosylmethionine in Myxococcus xanthus.
Topics: Bacterial Proteins; Biological Transport; Chloramphenicol; Kinetics; Lipid Metabolism; Methionine; Methylation; Molecular Weight; Myxococcales; S-Adenosylmethionine | 1983 |
Carboxyl methylation of cytosolic proteins in intact human erythrocytes. Identification of numerous methyl-accepting proteins including hemoglobin and carbonic anhydrase.
Topics: Blood Proteins; Carbonic Anhydrases; Cytosol; Erythrocytes; Hemoglobins; Humans; Kinetics; Methionine; Methylation; Molecular Weight; S-Adenosylmethionine; Tritium | 1984 |
[Demonstration of a new methylase in cell membranes of rat brain].
Topics: Animals; Brain; Cell Membrane; In Vitro Techniques; Male; Methylation; Methyltransferases; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1984 |
In vitro methylation and demethylation of methyl-accepting chemotaxis proteins in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Cell Membrane; Chemotactic Factors; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Molecular Weight; S-Adenosylmethionine | 1984 |
Membrane protein carboxyl methylation does not appear to be involved in the response of erythrocytes to cytoskeletal stress.
Topics: 2,4-Dinitrophenol; Calcimycin; Calcium; Chlorpromazine; Cytoskeleton; Dinitrophenols; Edetic Acid; Egtazic Acid; Erythrocytes; Humans; Membrane Proteins; Methylation; S-Adenosylmethionine | 1984 |
Methylated lysines and 3-methylhistidine in myosin: tissue and developmental differences.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chick Embryo; Histidine; Lysine; Methylation; Methylhistidines; Muscles; Myocardium; Myosins; Plants; Polyribosomes; Rabbits; Radioisotope Dilution Technique; S-Adenosylmethionine; Triticum; Tritium | 1984 |
Multiple methylation in processing of sensory signals during bacterial chemotaxis.
Topics: Bacterial Proteins; Bacteriophage lambda; Chemotaxis; DNA, Recombinant; Escherichia coli; Hydrolysis; Methylation; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Methylation of newly synthesized ribosomal protein L11 in a DNA-directed in vitro system.
Topics: Bacteriophage lambda; Chromosomes, Bacterial; DNA, Bacterial; DNA, Viral; Escherichia coli; Kinetics; Methylation; Molecular Weight; Ribosomal Proteins; S-Adenosylmethionine; Transduction, Genetic | 1980 |
Increased phospholipid methylation in the myocardium of hyperthyroid rats.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Hyperthyroidism; Male; Methylation; Microsomes; Myocardium; Phospholipids; Rats; S-Adenosylmethionine; Thyroxine | 1980 |
Studies of the identity of the unknown in protein hydrolysates.
Topics: Carbon Radioisotopes; Fungal Proteins; Hydrolysis; Methylamines; Methylation; Neurospora crassa; Proteins; S-Adenosylmethionine | 1980 |
Methylation increases sodium transport into A6 apical membrane vesicles: possible mode of aldosterone action.
Topics: Aldosterone; Amiloride; Amphibians; Animals; Biological Transport, Active; Cell Line; Cell Membrane; Kidney; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium; Tubercidin | 1984 |
Calcium signals and phospholipid methylation in eukaryotic cells.
Topics: Animals; Basophils; Calcium; Cell Communication; Cells; Cells, Cultured; Eukaryotic Cells; Ligands; Lymphocyte Activation; Mast Cells; Methylation; Mice; Mice, Inbred BALB C; Phospholipids; Rats; S-Adenosylmethionine; Thymus Gland | 1984 |
Sarcolemmal phosphatidylethanolamine N-methylation in diabetic cardiomyopathy.
Topics: Animals; Cardiomyopathies; Diabetes Mellitus, Experimental; Kinetics; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcolemma | 1984 |
Fibronectin-induced protein carboxy-O-methylation in aortic endothelial cells.
Topics: Adenosine; Animals; Aorta; Cattle; Cells, Cultured; Chemotaxis; Endothelium; Fibronectins; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; S-Adenosylmethionine; Toyocamycin | 1984 |
Purification and photoaffinity labelling of lipid methyltransferase from rat liver.
Topics: Affinity Labels; Animals; Azides; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Liver; Methylation; Rats; S-Adenosylmethionine | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
A possible model for the methylation of deoxycytidine in DNA.
Topics: Animals; Cytidine; Dimethyl Sulfoxide; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Methylation; Models, Biological; S-Adenosylmethionine; Structure-Activity Relationship | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Methylation of replicating and post-replicated mouse L-cell DNA.
Topics: Animals; Deoxyguanine Nucleotides; DNA; DNA Replication; Kinetics; L Cells; Methylation; Mice; Phosphorus Radioisotopes; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Significance of S-adenosylmethionine pools in the hypomethylation of ribosomal RNA during the propagation of tissue culture cells and oncogenesis.
Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Child; Fibroblasts; HeLa Cells; Humans; Kidney; Kinetics; Liver; Liver Regeneration; Male; Methylation; Osteosarcoma; Rats; Rats, Inbred Strains; RNA, Ribosomal; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Transient changes in phospholipid methylation induced by dexamethasone in lymphoid cells.
Topics: B-Lymphocytes; Cells, Cultured; Dexamethasone; Humans; Kinetics; Leukemia, Lymphoid; Methylation; Methyltransferases; Microsomes; Phospholipids; S-Adenosylmethionine; Tritium | 1983 |
Effect of exogenous S-adenosyl-L-methionine on phosphatidylcholine synthesis by isolated rat hepatocytes.
Topics: Animals; Deoxyadenosines; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Methylation; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1984 |
Induction of increased calcium uptake in liposomes having membrane proteins of chicken erythrocytes by S-adenosylmethionine.
Topics: Animals; Biological Transport; Calcium; Cell Membrane Permeability; Chickens; Erythrocyte Membrane; Erythrocytes; Liposomes; Membrane Proteins; Methylation; Phospholipids; S-Adenosylmethionine | 1983 |
In vitro methylation of histones in sea urchin nuclei during early embryogenesis.
Topics: Animals; Cell Nucleus; Embryo, Nonmammalian; Female; Histones; Kinetics; Methionine; Methylation; Protein Methyltransferases; S-Adenosylmethionine; Sea Urchins; Tritium | 1983 |
Methylation of liver DNA guanine in hamsters given hydrazine.
Topics: Animals; Cricetinae; DNA; Dose-Response Relationship, Drug; Glutathione; Guanine; Hydrazines; Liver; Male; Mesocricetus; Methylation; Monomethylhydrazine; S-Adenosylmethionine; Time Factors | 1983 |
Methylation of phospholipids in microsomes of the rat aorta.
Topics: Animals; Aorta, Thoracic; Chromatography, Thin Layer; Fluorescence Polarization; Homocysteine; Male; Methylation; Microsomes; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypsin; Type C Phospholipases | 1983 |
[Hormonal regulation of the synthesis of phosphatidylcholine by transmethylation].
Topics: Animals; Hormones; Humans; Liver; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1983 |
DNA-methylating activity of mycobacteria.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; DNA, Viral; Kinetics; Methylation; Methyltransferases; Mycobacterium; S-Adenosylmethionine; Thymus Gland | 1983 |
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia | 1983 |
Kinetics of enzymatic O-methylation: its value in assays for catecholamines in plasma.
Topics: Catechol O-Methyltransferase; Catecholamines; Humans; Kinetics; Mathematics; Methylation; S-Adenosylmethionine | 1984 |
Phosphatidylethanolamine methylation in leukocyte membrane preparations from allergic subjects: an unexpected result.
Topics: Adult; Asthma; Cell Membrane; Female; Granulocytes; Humans; Kinetics; Leukocyte Count; Leukocytes; Lymphocytes; Male; Methylation; Methyltransferases; Middle Aged; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; S-Adenosylmethionine | 1984 |
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin.
Topics: Animals; Cell Line; Cricetinae; Diphtheria Toxin; Drug Resistance; Female; Histidine; Methylation; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Protein Processing, Post-Translational; S-Adenosylmethionine | 1984 |
Interaction of DNA methyltransferase with aminofluorene and N-acetylaminofluorene modified poly(dC-dG).
Topics: 2-Acetylaminofluorene; Animals; Cell Nucleus; Circular Dichroism; DNA (Cytosine-5-)-Methyltransferases; Fluorenes; Kinetics; Liver; Methylation; Methyltransferases; Polydeoxyribonucleotides; Rats; S-Adenosylmethionine; Templates, Genetic | 1984 |
Stereochemical course of the transmethylation catalyzed by histamine N-methyltransferase.
Topics: Animals; Catalysis; Guinea Pigs; Histamine N-Methyltransferase; Methylation; Methyltransferases; S-Adenosylmethionine; Stereoisomerism | 1984 |
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet.
Topics: Animals; Cell Nucleus; Choline Deficiency; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Effects of adenosine dialdehyde on S-adenosylhomocysteine hydrolase and S-adenosylmethionine-dependent transmethylations in mouse L929 cells.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Hydrolases; Kinetics; L Cells; Methylation; Methyltransferases; Mice; S-Adenosylmethionine | 1984 |
Methylation of nucleolar RNA in HeLa cells studied by autoradiography.
Topics: Autoradiography; Cell Nucleolus; HeLa Cells; Humans; Methylation; Microscopy, Electron; RNA, Neoplasm; RNA, Ribosomal; S-Adenosylmethionine; Sulfur Radioisotopes | 1984 |
Differential membrane protein carboxyl-methylation of intact human erythrocytes by exogenous methyl donors.
Topics: Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Humans; Hydrolysis; Membrane Proteins; Methionine; Methylation; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
A tryptophan C-methyltransferase involved in streptonigrin biosynthesis in Streptomyces flocculus.
Topics: Chromatography, High Pressure Liquid; Methylation; Methyltransferases; Molecular Conformation; S-Adenosylmethionine; Streptomyces; Streptonigrin; Time Factors | 1984 |
Hypomethylation of DNA in ethionine-fed rats.
Topics: Adenosine; Animals; Deoxycytidine; DNA; Ethionine; Gene Expression Regulation; Liver; Male; Methylation; Rats; Rats, Inbred F344; S-Adenosylmethionine; Time Factors | 1984 |
A carbon-13 nuclear magnetic resonance study of the 3'-terminus of 16S ribosomal RNA of Escherichia coli specifically labeled with carbon-13 in the methylgroups of the m6(2)Am6(2)A sequence.
Topics: Base Sequence; Escherichia coli; Magnetic Resonance Spectroscopy; Methylation; Molecular Weight; Mutation; RNA, Ribosomal; S-Adenosylmethionine | 1982 |
Calmodulin modulates phospholipid methylation in Dictyostelium discoideum.
Topics: Animals; Brain; Calcium-Binding Proteins; Calmodulin; Cattle; Dictyostelium; Egtazic Acid; Kinetics; Methylation; Phospholipids; S-Adenosylmethionine | 1980 |
Enzymatic methylation of calmodulin in rat brain cytosol.
Topics: Animals; Brain; Calcium-Binding Proteins; Calmodulin; Cations; Cytosol; Egtazic Acid; Kinetics; Methylation; Methyltransferases; Molecular Weight; Peptide Fragments; Rats; S-Adenosylmethionine; Substrate Specificity; Sulfhydryl Reagents | 1980 |
Methylation of chemotaxis-specific proteins in Escherichia coli cells permeable to S-adenosylmethionine.
Topics: Aspartic Acid; Bacterial Proteins; Cell Membrane Permeability; Chemotactic Factors; Chemotaxis; Egtazic Acid; Escherichia coli; Ethylene Glycols; Genes; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Serine; Time Factors | 1980 |
Protein methylation in Caldariella acidophila, an extreme thermo-acidophilic archaebacterium.
Topics: Bacteria; Bacterial Proteins; Histone-Lysine N-Methyltransferase; Hot Temperature; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 1981 |
Inhibition of S-adenosylmethionine-linked methylation can lead to neurite extension in neuroblastoma cells.
Topics: Animals; Calcimycin; Clone Cells; Methylation; Mice; Neoplasms, Experimental; Neuroblastoma; Neurons; Phospholipids; Quinacrine; S-Adenosylmethionine | 1982 |
Membrane protein carboxyl methylation increases with human erythrocyte age. Evidence for an increase in the number of methylatable sites.
Topics: Anion Exchange Protein 1, Erythrocyte; Blood Proteins; Centrifugation, Density Gradient; Cytoskeletal Proteins; Erythrocyte Aging; Erythrocyte Membrane; Membrane Proteins; Methylation; Neuropeptides; S-Adenosylmethionine; Time Factors | 1983 |
Protein carboxyl methylation increases in parallel with differentiation of neuroblastoma cells.
Topics: Animals; Cell Differentiation; Cell Line; Clone Cells; Kinetics; Methionine; Methylation; Mice; Neoplasm Proteins; Neuroblastoma; S-Adenosylmethionine | 1983 |
Evidence for the existence of protein inhibitors for S-adenosyl-L-methionine-mediated methylation of phosphatidylethanolamine in rat liver cytosol.
Topics: Animals; Cell Membrane; Cytosol; In Vitro Techniques; Liver; Male; Methylation; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1983 |
Enzymatic properties of phospholipid methylation in rabbit platelets.
Topics: Animals; Blood Platelets; Buffers; Calcium; Cations, Divalent; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rabbits; S-Adenosylmethionine | 1983 |
Norepinephrine stimulation of phospholipid methylation in rat cortical synaptosomes: fact or artifact?
Topics: Animals; Cerebral Cortex; Chromatography, Thin Layer; Male; Methylation; Norepinephrine; Phospholipids; Propranolol; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptosomes | 1983 |
Depression of human sperm motility by inhibition of enzymatic methylation.
Topics: Adult; Humans; Male; Membrane Fluidity; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Sperm Motility; Spermatozoa | 1983 |
Effect of nitrous oxide and methionine treatments on hepatic S-adenosylmethionine and methylation reactions in the rat.
Topics: Animals; Formates; Liver; Male; Methionine; Methylation; Nitrous Oxide; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates | 1983 |
Structural requirements of the phospholipid substrate for phospholipid N-methylation in rat liver.
Topics: Animals; Cells, Cultured; Imidoesters; Indicators and Reagents; Kinetics; Liver; Male; Methylation; Microsomes, Liver; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Structure-Activity Relationship | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
S-adenosylmethionine metabolism and DNA methylation in hydrazine-treated rats.
Topics: Animals; Chromatography, High Pressure Liquid; DNA; Hydrazines; Liver; Male; Methylation; Rats; Rats, Inbred F344; S-Adenosylmethionine; Tritium | 1983 |
Pitfalls and problems in studies on the methylation of phosphatidylethanolamine.
Topics: Chromatography, Ion Exchange; Kinetics; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine | 1983 |
Enniatin synthetase, a novel type of multifunctional enzyme catalyzing depsipeptide synthesis in Fusarium oxysporum.
Topics: Amino Acids; Anti-Bacterial Agents; Fusarium; Iodoacetamide; Methylation; Molecular Weight; Organophosphorus Compounds; Pantetheine; Peptide Synthases; S-Adenosylmethionine; Substrate Specificity; Sulfhydryl Reagents | 1982 |
Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Lymphocytes; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1980 |
Studies on bacterial chemotaxis. VI. Effect of cheX mutation on the methylation of methyl-accepting chemotaxis protein of Escherichia coli.
Topics: Chemotaxis; Escherichia coli; Kinetics; Methylation; Mutation; S-Adenosylmethionine; Sulfates | 1980 |
Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferase.
Topics: Carbon Radioisotopes; Catechol O-Methyltransferase; Deuterium; Methylation; Radioisotope Dilution Technique; S-Adenosylmethionine; Structure-Activity Relationship; Tritium | 1980 |
Inhibition of sterol transmethylation by S-adenosylhomocysteine analogs.
Topics: Adenosine; Ergosterol; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Sterols; Structure-Activity Relationship | 1981 |
tRNA methylation. A rapid and simple method for determination of total radioactivity and methylated base distribution in the same sample.
Topics: Carbon Radioisotopes; Chromatography, Thin Layer; Escherichia coli; Methylation; Radioisotope Dilution Technique; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 1981 |
An in vitro study of the methylation of methyl-accepting chemotaxis protein of Escherichia coli. Construction of the system and effect of mutant proteins on the system.
Topics: Bacterial Proteins; Cell Membrane; Chemoreceptor Cells; Chemotactic Factors; Chemotaxis; Escherichia coli; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Mutation; S-Adenosylmethionine | 1981 |
[Heparin complexes with DNA: formation, properties and methylation in vitro].
Topics: Animals; DNA; DNA (Cytosine-5-)-Methyltransferases; Escherichia coli; Fibrin; Fibrinolysis; Heparin; Kinetics; Methylation; Rats; S-Adenosylmethionine | 1980 |
Multiple sites of methylation in the methyl accepting chemotaxis proteins of Escherichia coli.
Topics: Bacterial Proteins; Chemotactic Factors; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Membrane Proteins; Methionine; Methyl-Accepting Chemotaxis Proteins; Methylation; Peptide Fragments; S-Adenosylmethionine; Tritium | 1981 |
S-adenosyl-L-methionine antagonizes ethynylestradiol-induced bile cholesterol supersaturation in humans without modifying the estrogen plasma kinetics.
Topics: Adult; Bile; Cholesterol; Ethinyl Estradiol; Female; Humans; Kinetics; Lipid Metabolism; Male; Methylation; Middle Aged; S-Adenosylmethionine | 1982 |
Characteristics of protein carboxyl methylation in the rat hypothalamus.
Topics: Animals; Hypothalamus; Kinetics; Male; Methionine; Methylation; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Tritium | 1982 |
The effect of pharmacologic inhibition of phospholipid methylation on human platelet function.
Topics: Adenosine; Adenosylhomocysteinase; Blood Platelets; Humans; Hydrolases; Methylation; Phosphatidylethanolamines; Phospholipids; Platelet Aggregation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1982 |
Phospholipid methylation and noradrenaline exchanges in a synaptosomal preparation from the rat brain.
Topics: Animals; Cerebral Cortex; Intracellular Membranes; Kinetics; Male; Methylation; Methyltransferases; Norepinephrine; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptosomes; Yohimbine | 1982 |
Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase.
Topics: Brain; Catechol O-Methyltransferase; Cell Membrane; Dopamine; Humans; Kinetics; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tropolone | 1982 |
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Repair; Guanine; In Vitro Techniques; Methylation; S-Adenosylmethionine; Scintillation Counting; Spectrophotometry, Ultraviolet | 1982 |
Stimulation of fatty acid methylation in human red cell membranes by phospholipase A2 activation.
Topics: Dose-Response Relationship, Drug; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Humans; Lung; Melitten; Methionine; Methylation; Oleic Acid; Oleic Acids; Phospholipases; Phospholipases A; Phospholipases A2; S-Adenosylmethionine; Substrate Specificity | 1982 |
Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor.
Topics: Animals; Cell Membrane; Electric Organ; Humans; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Receptors, Cholinergic; S-Adenosylmethionine; Torpedo | 1982 |
Role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholine by hepatocytes isolated from choline-deficient rats.
Topics: Animals; Choline; Choline Deficiency; In Vitro Techniques; Lipoproteins; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Triglycerides | 1982 |
Biosynthesis of S-methyl-N-oleoylmercaptoethylamide from oleoyl coenzyme A and S-adenosylmethionine.
Topics: Acyl Coenzyme A; Animals; Cell Membrane; Erythrocytes; Humans; Kinetics; Lung; Male; Mass Spectrometry; Mercaptoethylamines; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Subcellular Fractions; Tissue Distribution; Tritium | 1982 |
Methinin: a peptide inhibitor of methylation.
Topics: Animals; Chemical Phenomena; Chemistry; In Vitro Techniques; Liver; Methylation; Methyltransferases; Peptides; Rabbits; Rats; S-Adenosylmethionine | 1982 |
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.
Topics: Chromatography, High Pressure Liquid; DNA Glycosylases; DNA, Bacterial; Guanine; Methylation; Micrococcus; N-Glycosyl Hydrolases; S-Adenosylmethionine | 1982 |
Role of transmethylation reactions in cellular motility and phagocytosis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adult; Animals; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Guinea Pigs; Humans; In Vitro Techniques; Lactones; Macrophages; Methylation; Models, Biological; Monocytes; Peptides; Phagocytosis; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Methylation of membrane proteins in human erythrocytes. Identification and characterization of polypeptides methylated in lysed cells.
Topics: Chymotrypsin; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methylation; Molecular Weight; Peptide Fragments; Peptides; S-Adenosylmethionine; Trypsin | 1981 |
Biogenesis of endoplasmic reticulum phosphatidylcholine. Translocation of intermediates across the membrane bilayer during methylation of phosphatidylethanolamine.
Topics: Animals; Carbon Radioisotopes; Endoplasmic Reticulum; Kinetics; Lipid Bilayers; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Taurocholic Acid; Trypsin; Type C Phospholipases | 1981 |
Presence of the phospholipid methylation pathway in mammalian cultured cells.
Topics: Animals; Cells, Cultured; Liver; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine | 1981 |
In vitro methylation of DNA with Hpa II methylase.
Topics: Animals; Base Sequence; Deoxyribonucleases; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; DNA, Bacterial; Haemophilus; Methylation; Methyltransferases; Plasmids; S-Adenosylmethionine | 1981 |
Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Male; Methylation; Mice; Nerve Tissue Proteins; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Stereochemical course of the methylation of the polygalacturonic acid carboxyl groups of pectin.
Topics: Methylation; Methyltransferases; Molecular Conformation; Pectins; Plants; S-Adenosylmethionine; Stereoisomerism | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Glucagon and epinephrine-stimulated phospholipid methylation in hepatic microsomes.
Topics: Animals; Epinephrine; Glucagon; Male; Methylation; Methyltransferases; Microsomes, Liver; Phospholipids; Rats; S-Adenosylmethionine | 1981 |
Blood levels of S-adenosylmethionine in unmedicated schizophrenic and depressive patients.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Female; Humans; Male; Methylation; Middle Aged; S-Adenosylmethionine; Schizophrenia | 1981 |
Site of prenylation reaction in synthesis of phylloquinone (vitamin K1) by spinach chloroplasts.
Topics: Cell Membrane; Chloroplasts; Methylation; Naphthols; Phytic Acid; Plants; S-Adenosylmethionine; Vitamin K 1 | 1981 |
Nonpolar lipid methylation. Biosynthesis of fatty acid methyl esters by rat lung membranes using S-adenosylmethionine.
Topics: Animals; Cell Membrane; Fatty Acids; Gas Chromatography-Mass Spectrometry; Intracellular Membranes; Kinetics; Lung; Male; Membrane Lipids; Methylation; Organ Specificity; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Subcellular Fractions | 1981 |
Stimulation of transcription by S-adenosyl-L-homocysteine and virion-encapsidated methyl donor in spring viraemia of carp virus.
Topics: Animals; Capsid; Carps; Homocysteine; Kinetics; Methylation; Rhabdoviridae; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic; Virion | 1981 |
[Possible regulatory role of 5'-methylthioadenosine on enzymatic methyl esterification of membrane protein].
Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein O-Methyltransferase; S-Adenosylmethionine; Thionucleosides | 1981 |
The synthesis of choline plasmalogen by the methylation pathway in rat brain.
Topics: Animals; Brain; Male; Methylation; Microsomes; Phosphatidylcholines; Plasmalogens; Rats; S-Adenosylmethionine | 1981 |
Carboxymethylation of membrane proteins of irreversibly sickled erythrocytes.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methionine; Methylation; Reference Values; S-Adenosylmethionine; Tritium | 1981 |
Reduced erythrocyte membrane protein methylation in sickle cell anemia.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Lipids; Membrane Proteins; Methionine; Methylation; Phospholipids; Reference Values; S-Adenosylmethionine; Tritium | 1981 |
Evidence for two methyltransferase involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in the rat liver.
Topics: Animals; Kinetics; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Subcellular Fractions | 1981 |
Ethanolamine plasmalogen methylation by rabbit myocardial membranes.
Topics: Animals; Kinetics; Male; Methylation; Methyltransferases; Microscopy, Electron; Myocardium; Phosphatidylethanolamines; Phospholipids; Plasmalogens; Rabbits; S-Adenosylmethionine | 1981 |
Changes in phospholipid methyltransferases and membrane microviscosity during induction of rat liver microsomal cytochrome P-450 by phenobarbital and 3-methylcholanthrene.
Topics: Animals; Cell Membrane; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylation; Methylcholanthrene; Methyltransferases; Microsomes, Liver; Phenobarbital; Phospholipids; Rats; S-Adenosylmethionine; Temperature; Tritium; Viscosity | 1981 |
In vivo carboxyl methylation of human eruthrocyte membrane proteins.
Topics: Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methionine; Methylation; Puromycin; S-Adenosylmethionine | 1980 |
Polymethylpolysaccharide synthesis in an ethionine-resistant mutant of Mycobacterium smegmatis.
Topics: Drug Resistance, Microbial; Ethionine; Fatty Acids; Lipids; Methionine Adenosyltransferase; Methylation; Mutation; Mycobacterium; Polysaccharides, Bacterial; S-Adenosylmethionine | 1980 |
The effect of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid on the growth and metabolism of Walker carcinosarcoma in vitro.
Topics: Aminobutyrates; Animals; Carcinoma 256, Walker; Cells, Cultured; DNA, Neoplasm; Methionine; Methylation; Neoplasm Proteins; RNA, Neoplasm; RNA, Transfer; S-Adenosylmethionine | 1980 |
S-adenosylmethionine levels and protein methylation during morphogenesis of Mucor racemosus.
Topics: Fungal Proteins; Methylation; Morphogenesis; Mucor; S-Adenosylmethionine; Spermidine; Spermine | 1980 |
Accumulation of methyl-deficient rat liver messenger ribonucleic acid on ethionine administration.
Topics: Animals; Carcinoma, Ehrlich Tumor; Ethionine; Liver; Male; Methylation; Mice; Rats; RNA Caps; RNA, Messenger; S-Adenosylmethionine; tRNA Methyltransferases; Vaccinia virus | 1980 |
Methylation of erythrocyte membrane phospholipids in patients with myotonic and Duchenne muscular dystrophy.
Topics: Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Lipids; Methylation; Muscular Dystrophies; Phosphatidylcholines; Phospholipids; S-Adenosylmethionine | 1980 |
Transverse asymmetry of the enzymes that catalyse methylation of phosphatidylethanolamine to yield phosphatidylcholine in rat liver microsomal fraction.
Topics: Animals; Lipid Bilayers; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1980 |
Ethynylestradiol-induced impairment of bile secretion in the rat: protective effects of S-adenosyl-L-methionine and its implication in estrogen metabolism.
Topics: Animals; Bile; Cholestasis; Chromatography, Gas; Estrogens; Ethinyl Estradiol; Female; Lipids; Methylation; Rats; S-Adenosylmethionine | 1981 |
Prenylcysteine-directed carboxyl methyltransferase activity in human neutrophil membranes.
Topics: Amino Acid Sequence; Animals; Autoradiography; Brain; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cytosol; Detergents; Electrophoresis, Polyacrylamide Gel; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Methylation; Microsomes; Microsomes, Liver; Molecular Sequence Data; Molecular Weight; Neutrophils; Protein Methyltransferases; Protein Prenylation; ras Proteins; Rats; S-Adenosylmethionine; Sulfur Radioisotopes | 1995 |
Partial restoration of impaired alpha 1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Animals; Fluorescence Polarization; Inositol 1,4,5-Trisphosphate; Male; Membrane Fluidity; Membrane Lipids; Methylation; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Viscosity | 1995 |
NodS is an S-adenosyl-L-methionine-dependent methyltransferase that methylates chitooligosaccharides deacetylated at the non-reducing end.
Topics: Acetylglucosamine; Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Chitin; Escherichia coli; Genes, Bacterial; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Weight; Oligosaccharides; Recombinant Fusion Proteins; Rhizobiaceae; Rhizobium; S-Adenosylmethionine; Substrate Specificity | 1995 |
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine | 1993 |
Structural specificity of substrate for S-adenosylmethionine:protein arginine N-methyltransferases.
Topics: Amino Acid Sequence; Animals; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Methylation; Molecular Sequence Data; Myelin Basic Protein; Oligopeptides; Peptide Fragments; Protein-Arginine N-Methyltransferases; Rats; Ribonucleoproteins; S-Adenosylmethionine; Substrate Specificity; Trypsin | 1995 |
The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor.
Topics: Azacitidine; Base Sequence; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Escherichia coli; Hot Temperature; Methylation; Models, Chemical; Molecular Sequence Data; Oligonucleotides; S-Adenosylmethionine; Sodium Dodecyl Sulfate | 1995 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Thiopurine induced disturbance of DNA methylation in human malignant cells.
Topics: Antimetabolites, Antineoplastic; Cell Death; DNA, Neoplasm; Humans; Mercaptopurine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Thioinosine; Thionucleotides; Tumor Cells, Cultured | 1995 |
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Escherichia coli; Humans; Methylation; Molecular Structure; Mutagenesis; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymine | 1995 |
Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats.
Topics: Animals; Base Sequence; Cytosine; Folic Acid Deficiency; Genes, p53; Liver; Male; Methylation; Molecular Sequence Data; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1995 |
Self-methylation of the M.BspRI methyltransferase.
Topics: Amino Acid Sequence; Cysteine; DNA-Cytosine Methylases; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 1995 |
Sequence-specific binding of DNA by the EcoRV restriction and modification enzymes with nucleic acid and cofactor analogues.
Topics: Adenosine; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA; Escherichia coli; Magnesium; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1995 |
Lack of an effect of Madopar on the disposition of tolcapone and its 3-O-methylated metabolite in rats.
Topics: Animals; Benserazide; Benzophenones; Biotransformation; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Enzyme Inhibitors; Half-Life; Injections, Intravenous; Levodopa; Male; Methylation; Nitrophenols; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tissue Distribution; Tolcapone | 1995 |
S-adenosyl-L-methionine modulates firing rate of dorsal motor nucleus of the vagus neurones in vitro.
Topics: Action Potentials; Alkanesulfonates; Animals; Dose-Response Relationship, Drug; Electrophysiology; Female; Male; Methylation; Motor Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Theobromine; Vagus Nerve; Xanthines | 1994 |
Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme.
Topics: Animals; Base Sequence; Catechol O-Methyltransferase; Cell Membrane; Dopamine; Enzyme Stability; Hot Temperature; Humans; Hydroxybenzoates; Kinetics; Levodopa; Magnesium; Methylation; Models, Molecular; Molecular Sequence Data; Norepinephrine; Rats; Recombinant Proteins; S-Adenosylmethionine | 1995 |
An abnormal methylation ratio induces hypomethylation in vitro in the brain of pig and man, but not in rat.
Topics: Animals; Brain; Death; Female; Humans; Methylation; Methyltransferases; Nitrous Oxide; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Swine; Time Factors; Vitamin B 12 Deficiency | 1995 |
Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Homocysteine; Humans; Hydrolases; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Uremia | 1995 |
S-adenosyl methionine alters the DNA contacts of the EcoKI methyltransferase.
Topics: Base Sequence; DNA; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Sulfuric Acid Esters; Temperature | 1995 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Increased membrane-protein methylation in hereditary spherocytosis. A marker of cytoskeletal disarray.
Topics: Cytoskeleton; Erythrocyte Membrane; Esterification; Humans; Membrane Proteins; Methylation; Protein Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrin; Spherocytosis, Hereditary | 1995 |
HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair.
Topics: Base Sequence; Cytosine; Deamination; Dinucleoside Phosphates; DNA; DNA Glycosylases; DNA Repair; DNA-Cytosine Methylases; Kinetics; Methylation; Molecular Sequence Data; Mutagenesis; N-Glycosyl Hydrolases; Nucleic Acid Heteroduplexes; S-Adenosylmethionine; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 1995 |
M.HhaI binds tightly to substrates containing mismatches at the target base.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Dinucleoside Phosphates; DNA; DNA-Cytosine Methylases; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Heteroduplexes; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Uracil | 1995 |
Abnormal synthesis of N-methylated phospholipids during calcium paradox of the heart.
Topics: Animals; Calcium; Heart; In Vitro Techniques; Kinetics; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardial Contraction; Myocardium; Perfusion; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum | 1995 |
Alteration in the phosphatidylcholine biosynthesis of rat liver microsomes caused by vitamin B6 deficiency.
Topics: Animals; Caseins; Choline; Choline Kinase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diacylglycerol Cholinephosphotransferase; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1995 |
Demonstration of hypomethylation of proteins in the brain of pigs (but not in rats) associated with chronic vitamin B12 inactivation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Female; Methylation; Nitrous Oxide; Proteins; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Vitamin B 12 Deficiency | 1995 |
Reaction in alphavirus mRNA capping: formation of a covalent complex of nonstructural protein nsP1 with 7-methyl-GMP.
Topics: Alphavirus; Cations, Divalent; Cells, Cultured; Diphosphates; Guanosine Triphosphate; Methylation; Methyltransferases; Recombinant Proteins; RNA Cap Analogs; RNA Caps; RNA, Viral; S-Adenosylmethionine; Substrate Specificity | 1995 |
Spontaneous methylation of hemoglobin by S-adenosyl-methionine by a specific and saturable mechanism.
Topics: Hemoglobins; Humans; Methylation; S-Adenosylmethionine | 1994 |
The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Gene Deletion; Genes, Fungal; Methylation; Molecular Sequence Data; Open Reading Frames; S-Adenosylmethionine; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology | 1995 |
Characterization of an Arabidopsis thaliana DNA hypomethylation mutant.
Topics: Arabidopsis; DNA Modification Methylases; DNA, Plant; Genes, Plant; Homozygote; Methylation; Mutation; Phenotype; S-Adenosylmethionine; Substrate Specificity | 1995 |
Methylation in fertilised and parthenogenetic preimplantation mouse embryos.
Topics: Animals; DNA Modification Methylases; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Genomic Imprinting; Homocysteine; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Parthenogenesis; Pregnancy; S-Adenosylmethionine | 1994 |
Activation-dependent carboxyl methylation of neutrophil G-protein gamma subunit.
Topics: Antibodies; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanine Nucleotides; Humans; Immunoblotting; In Vitro Techniques; Iodine Radioisotopes; Macromolecular Substances; Methylation; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; S-Adenosylmethionine; Tritium | 1995 |
A novel Tn10 tetracycline regulon system controlling expression of the bacteriophage T3 gene encoding S-adenosyl-L-methionine hydrolase.
Topics: Antiporters; Bacterial Proteins; Bacteriophage T3; Carrier Proteins; Chlortetracycline; DNA Transposable Elements; Enzyme Induction; Escherichia coli; Hydrolases; Methylation; Plasmids; Promoter Regions, Genetic; Regulon; S-Adenosylmethionine | 1994 |
Interaction of EcoP15I DNA methyltransferase with oligonucleotides containing the asymmetric sequence 5'-CAGCAG-3'.
Topics: Base Sequence; Cations, Divalent; Deoxyribonucleases, Type III Site-Specific; DNA; Escherichia coli; Kinetics; Methylation; Methyltransferases; Molecular Sequence Data; Oligodeoxyribonucleotides; Photochemistry; Protein Binding; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1994 |
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cerebellum; Cysteine; Diterpenes; DNA Primers; GTP-Binding Proteins; Humans; Intracellular Membranes; Kinetics; Methylation; Microsomes; Molecular Sequence Data; Nerve Tissue Proteins; Polymerase Chain Reaction; Protein Prenylation; rab1 GTP-Binding Proteins; rab3 GTP-Binding Proteins; Recombinant Proteins; S-Adenosylmethionine; Structure-Activity Relationship; Tritium | 1994 |
Effects of the disruption of transmethylation in the central nervous system: an animal model.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Cystathionine; Depressive Disorder; Folic Acid Deficiency; Liver; Methylation; Methyltransferases; Plasma; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B Deficiency | 1994 |
Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein.
Topics: Amino Acid Sequence; Base Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Heme; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Sequence Data; NADP; Recombinant Proteins; S-Adenosylmethionine; Uroporphyrinogens; Uroporphyrins | 1994 |
Novel methyltransferase activity modifying the carboxy terminal bis(geranylgeranyl)-Cys-Ala-Cys structure of small GTP-binding proteins.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Cell Membrane; GTP-Binding Proteins; Kinetics; Methylation; Methyltransferases; Molecular Sequence Data; Peptide Fragments; Protein Prenylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Automethylation of protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase, a response to enzyme aging.
Topics: Animals; Cattle; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Erythrocyte Aging; Erythrocytes; Kinetics; Methylation; Molecular Weight; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; S-Adenosylmethionine | 1994 |
Mechanism of resistance to the antibiotic trichothecin in the producing fungi.
Topics: Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Fusarium; Methylation; Mitosporic Fungi; Peptide Biosynthesis; Peptides; Protein Biosynthesis; Ribosomes; S-Adenosylmethionine; Saccharomyces cerevisiae; Trichothecenes | 1994 |
Self-methylation of BspRI DNA-methyltransferase.
Topics: Amino Acid Sequence; Binding, Competitive; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine; DNA; DNA-Cytosine Methylases; Escherichia coli; Methylation; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Reagents; Tritium | 1994 |
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
Topics: Animals; Ethionine; Folic Acid Deficiency; Homocysteine; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1994 |
m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain.
Topics: Animals; Base Sequence; Binding Sites; Binding, Competitive; Cell Nucleus; Cytosol; Dithiothreitol; Ethylmaleimide; Female; Iodoacetates; Iodoacetic Acid; Methylation; Methyltransferases; Molecular Sequence Data; Oocytes; Ribonucleoprotein, U1 Small Nuclear; RNA Caps; RNA, Small Nuclear; S-Adenosylmethionine; Transcription, Genetic; Xenopus | 1994 |
Effects of prolonged aspirin or acetaminophen administration to rats on liver folate content and distribution. Relation to DNA methylation and S-adenosylmethionine.
Topics: Acetaminophen; Animals; Aspirin; DNA; Drug Administration Schedule; Folic Acid; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
S-adenosyl-L-methionine-mediated enzymatic methylations in the rat retinal membranes.
Topics: Animals; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; Retina; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
DNA recognition by the EcoK methyltransferase. The influence of DNA methylation and the cofactor S-adenosyl-L-methionine.
Topics: Allosteric Regulation; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; In Vitro Techniques; Kinetics; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; Osmolar Concentration; Protein Binding; Protein Conformation; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity | 1993 |
S-adenosyl-l-methionine inhibits phosphoinositide metabolism in the rat brain synaptosomal suspensions.
Topics: Analysis of Variance; Animals; Brain; Cyclic AMP; In Vitro Techniques; Inositol Phosphates; Kinetics; Methylation; Norepinephrine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Synaptosomes | 1993 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Kinetic characterization of the EcaI methyltransferase.
Topics: Base Sequence; Deoxyribonucleases, Type II Site-Specific; DNA; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; S-Adenosylmethionine; Substrate Specificity | 1993 |
Enzymatic O-methylation of catechol estrogens in red blood cells: differences in animal species and strains.
Topics: Adult; Animals; Dogs; Erythrocytes; Estradiol; Estrogens, Catechol; Guinea Pigs; Humans; Macaca fascicularis; Methylation; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; S-Adenosylmethionine; Species Specificity | 1993 |
Carboxyl methylation of protein phosphatase 2A from Xenopus eggs is stimulated by cAMP and inhibited by okadaic acid.
Topics: Animals; Calcium; Calmodulin; Caseins; Cattle; Cyclic AMP; Cytosol; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Female; Kinetics; Methylation; Okadaic Acid; Ovum; Phosphoprotein Phosphatases; Protein Phosphatase 2; S-Adenosylmethionine; Second Messenger Systems; Substrate Specificity; Tetradecanoylphorbol Acetate; Xenopus laevis | 1994 |
Diethyldithiocarbamate S-methylation: evidence for catalysis by human liver thiol methyltransferase and thiopurine methyltransferase.
Topics: Aldehyde Dehydrogenase; Catalysis; Cations; Chromatography, Ion Exchange; Cytosol; Ditiocarb; Enzyme Stability; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Methylation; Methyltransferases; Microsomes, Liver; Proteins; S-Adenosylmethionine; Time Factors | 1993 |
Protein phosphatase 2A catalytic subunit is methyl-esterified at its carboxyl terminus by a novel methyltransferase.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Chromatography, DEAE-Cellulose; Kinetics; Macromolecular Substances; Methylation; Molecular Sequence Data; Peptide Fragments; Phosphoprotein Phosphatases; Protein Methyltransferases; Protein Phosphatase 2; S-Adenosylmethionine; Tritium | 1993 |
Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group.
Topics: Bacterial Proteins; Base Sequence; DNA, Single-Stranded; Methylation; Methyltransferases; Molecular Sequence Data; Oxidation-Reduction; Oxygenases; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1993 |
Prenylated protein methyltransferase of rat cerebellum is developmentally co-expressed with its substrates.
Topics: Aging; Animals; Animals, Newborn; Cerebellum; GTP-Binding Proteins; Methylation; Nerve Tissue Proteins; Protein Methyltransferases; Rats; S-Adenosylmethionine; Subcellular Fractions; Synaptosomes | 1993 |
A peptide inhibitor for S-adenosyl-L-methionine-dependent transmethylation reactions. Purification and characterization.
Topics: Amino Acids; Animals; Liver; Methylation; Molecular Weight; Peptides; Rats; S-Adenosylmethionine | 1993 |
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils.
Topics: Cell Membrane; Cytosol; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Methionine; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Methyltransferases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); rap GTP-Binding Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; S-Adenosylmethionine; Signal Transduction; Tritium | 1993 |
Phospholipid methylation in brain membrane preparations: kinetic mechanism.
Topics: Animals; Brain; Erythrocytes; Kinetics; Male; Membranes; Methylation; Methyltransferases; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1993 |
A novel antiviral strategy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; DNA, Viral; HIV; HIV Infections; HIV Seropositivity; Humans; Methylation; Proviruses; S-Adenosylmethionine; Tetrahydrofolates; Virus Replication; Vitamin B 12 | 1993 |
Uptake and metabolism of S-adenosyl-L-methionine by Leishmania mexicana and Leishmania braziliensis promastigotes.
Topics: Amino Acids; Animals; Biological Transport; Carbohydrates; Kinetics; Leishmania braziliensis; Leishmania mexicana; Lipids; Methylation; Morphogenesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1993 |
Kinetic properties of bovine brain protein L-isoaspartyl methyltransferase determined using a synthetic isoaspartyl peptide substrate.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Brain; Cattle; Chromatography, High Pressure Liquid; Kinetics; Methylation; Molecular Sequence Data; Peptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium | 1993 |
Bile acid transformations by Alcaligenes recti.
Topics: Alcaligenes; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Structure; S-Adenosylmethionine; Spectrometry, Mass, Fast Atom Bombardment; Ursodeoxycholic Acid | 1993 |
Presteady state kinetics of an S-adenosylmethionine-dependent enzyme. Evidence for a unique binding orientation requirement for EcoRI DNA methyltransferase.
Topics: Adenine; Base Sequence; Binding Sites; DNA; Escherichia coli; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Conformation; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1993 |
Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure. Evidence for high levels of the natural inhibitor S-adenosylhomocysteine.
Topics: Adolescent; Adult; Aged; Child; Erythrocyte Membrane; Erythrocytes; Esterification; Female; Humans; Kidney Failure, Chronic; Male; Membrane Proteins; Methylation; Middle Aged; Models, Biological; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Urea | 1993 |
Evidence for the existence of independent chloromethane- and S-adenosylmethionine-utilizing systems for methylation in Phanerochaete chrysosporium.
Topics: Acetophenones; Basidiomycota; Hydrogen-Ion Concentration; Kinetics; Methyl Chloride; Methylation; S-Adenosylmethionine | 1993 |
Affinity purification of ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilon N-methyltransferase.
Topics: Chromatography, Affinity; Enzymes, Immobilized; Histone-Lysine N-Methyltransferase; Ligands; Membranes, Artificial; Methylation; Molecular Weight; Pisum sativum; Polyvinyls; S-Adenosylmethionine; Spinacia oleracea; Substrate Specificity | 1995 |
Mutations affecting the biosynthesis of S-adenosylmethionine cause reduction of DNA methylation in Neurospora crassa.
Topics: Amino Acids; Culture Media; DNA, Fungal; Genotype; Methionine; Methylation; Mutation; Neurospora crassa; S-Adenosylmethionine; Temperature | 1995 |
Crithidia luciliae: effect of purine starvation on S-adenosyl-L-methionine uptake and protein methylation.
Topics: Adenosine; Animals; Crithidia; Cycloheximide; Decarboxylation; Methionine; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Purines; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1995 |
DNA binding and methyl transfer catalysed by mouse DNA methyltransferase.
Topics: Animals; Base Composition; Binding, Competitive; DNA; DNA Modification Methylases; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Kinetics; Methylation; Mice; Oligodeoxyribonucleotides; Peptides; S-Adenosylmethionine; Trypsin | 1995 |
Evidence for a covalent intermediate in the S-adenosyl-L-methionine-dependent transmethylation reaction catalysed by sirohaem synthase.
Topics: Catalysis; Circular Dichroism; Escherichia coli; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 1996 |
[Participation of methylcobalamin in DNA methylation in vitro].
Topics: Animals; Cattle; DNA; DNA Modification Methylases; DNA, Bacterial; Liver; Methylation; Micrococcus luteus; Rats; S-Adenosylmethionine; Vitamin B 12 | 1995 |
Mechanism and structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:delta 24(25)-sterol methyl transferase from Saccharomyces cerevisiae.
Topics: Cell Fractionation; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Kinetics; Methylation; Methyltransferases; Microsomes; Models, Biological; S-Adenosylmethionine; Saccharomyces cerevisiae; Solubility; Sterols; Substrate Specificity | 1996 |
N6-methyladenosine inhibits murine erythroleukemia cell maturation by blocking methylation of RNA and memory via conversion to S-(N6-methyl)-adenosylhomocysteine.
Topics: Adenosine; Animals; Cell Differentiation; Cell Division; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1995 |
Mono- and dimethylation of arsenic in rat liver cytosol in vitro.
Topics: Animals; Arsenates; Arsenic; Arsenicals; Arsenites; Cacodylic Acid; Edetic Acid; Egtazic Acid; Glutathione; Liver; Male; Mercuric Chloride; Methylation; Methyltransferases; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Selenite; Vitamin B 12 | 1996 |
Mechanisms for the involvement of DNA methylation in colon carcinogenesis.
Topics: Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Complementary; DNA, Neoplasm; Escherichia coli; Humans; Intestinal Mucosa; Methylation; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine; Uracil-DNA Glycosidase | 1996 |
The type I restriction endonuclease R.EcoR124I: over-production and biochemical properties.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Base Sequence; Chromatography, Gel; Deoxyribonucleases, Type I Site-Specific; DNA; DNA, Circular; DNA, Superhelical; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Magnesium; Methylation; Molecular Sequence Data; Molecular Weight; Plasmids; Promoter Regions, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
Vaccinia virus mRNA (guanine-7-)methyltransferase: mutational effects on cap methylation and AdoHcy-dependent photo-cross-linking of the cap to the methyl acceptor site.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Cross-Linking Reagents; DNA Mutational Analysis; Escherichia coli; Guanine Nucleotides; Kinetics; Magnesium; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotidyltransferases; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; RNA Caps; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Ultraviolet Rays; Vaccinia virus | 1996 |
Low whole-blood S-adenosylmethionine and correlation between 5-methyltetrahydrofolate and homocysteine in coronary artery disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Cohort Studies; Coronary Disease; Erythrocytes; Female; Follow-Up Studies; Homocysteine; Humans; Isoenzymes; Lymphocytes; Male; Methionine Adenosyltransferase; Methylation; Middle Aged; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion.
Topics: Animals; Binding, Competitive; Catalysis; Enzyme Inhibitors; Esterases; Ethers, Cyclic; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lactones; Male; Methylation; Molecular Weight; Okadaic Acid; Peptide Fragments; Phosphoprotein Phosphatases; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1996 |
Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.
Topics: Amino Acid Sequence; Base Sequence; Child, Preschool; Cloning, Molecular; DNA, Complementary; DNA, Neoplasm; Enzyme Stability; Erythrocytes; Gene Frequency; Humans; Kinetics; Male; Mercaptopurine; Methylation; Methyltransferases; Molecular Sequence Data; Point Mutation; Polymorphism, Restriction Fragment Length; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; RNA, Messenger; S-Adenosylmethionine; White People; Yeasts | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
A specific protein carboxyl methylesterase that demethylates phosphoprotein phosphatase 2A in bovine brain.
Topics: Amino Acid Sequence; Animals; Brain; Carboxylic Ester Hydrolases; Cattle; Ethers, Cyclic; Methanol; Methylation; Molecular Sequence Data; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2; S-Adenosylmethionine; Substrate Specificity | 1996 |
Overproduction, purification and characterization of M.EcoHK31I, a bacterial methyltransferase with two polypeptides.
Topics: Amino Acid Sequence; DNA; DNA-Cytosine Methylases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Overlapping; Kinetics; Methylation; Molecular Sequence Data; Molecular Weight; Peptides; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine | 1996 |
Induction of murine erythroleukemia cell differentiation is associated with methylation and differential stability of poly(A)+ RNA transcripts.
Topics: Actins; Adenosine; Animals; Cell Differentiation; Cell Division; Cycloleucine; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Globins; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Proto-Oncogene Proteins c-myc; Ribonucleotides; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1996 |
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.
Topics: Animals; Antimetabolites, Antineoplastic; Base Composition; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Repair; DNA Replication; HeLa Cells; Humans; Methylation; Molecular Sequence Data; S-Adenosylmethionine; Thioguanine | 1996 |
17 beta-Estradiol metabolism by hamster hepatic microsomes. Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens.
Topics: Animals; Ascorbic Acid; Catechol O-Methyltransferase; Cricetinae; Estradiol; Estrogens, Catechol; Glutathione; Inactivation, Metabolic; Magnesium; Male; Mesocricetus; Methylation; Microsomes, Liver; S-Adenosylmethionine; Steroid 16-alpha-Hydroxylase | 1996 |
Effect of hypoxia on hepatic DNA methylation and tRNA methyltransferase in rat: similarities to effects of methyl-deficient diets.
Topics: Animals; Blotting, Northern; DNA; Hypoxia; Liver; Male; Methionine Adenosyltransferase; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; tRNA Methyltransferases | 1996 |
Striatal dopamine depletion, tremors, and hypokinesia following the intracranial injection of S-adenosylmethionine: a possible role of hypermethylation in parkinsonism.
Topics: Animals; Antiparkinson Agents; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Hypokinesia; Injections, Intraventricular; Levodopa; Male; Methylation; Motor Activity; Neostriatum; Parkinson Disease; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tremor | 1995 |
A methyl-accepting protein involved in multiple-sugar chemotaxis by Cellulomonas gelida.
Topics: Bacterial Proteins; Carbohydrate Metabolism; Cell Fractionation; Cell Membrane; Cellobiose; Chemotaxis; Culture Media; Gram-Positive Asporogenous Rods; Membrane Proteins; Methanol; Methionine; Methyl-Accepting Chemotaxis Proteins; Methylation; Mutation; S-Adenosylmethionine | 1996 |
Methylation inhibitors can increase the rate of cytosine deamination by (cytosine-5)-DNA methyltransferase.
Topics: Bacteria; Binding, Competitive; Deamination; DNA; DNA-Cytosine Methylases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Methylation; Protein Binding; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1996 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide.
Topics: Bendroflumethiazide; Diuretics; Erythrocytes; Furosemide; Humans; In Vitro Techniques; Lethal Dose 50; Mercaptopurine; Methylation; Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Trichlormethiazide | 1996 |
Resistance to inhibitors of S-adenosyl-L-homocysteine hydrolase in C1300 murine neuroblastoma tumor cells is associated with increased methionine adenosyltransferase activity.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Hydrolases; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred A; Neuroblastoma; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium; Tumor Cells, Cultured | 1995 |
Down-regulation of S-adenosylhomocysteine hydrolase in the active methyl transfer system in the brain of genetically epileptic El mice.
Topics: Adenosylhomocysteinase; Animals; Brain; Chromatography, High Pressure Liquid; Down-Regulation; Epilepsy; Hydrolases; Methylation; Mice; Mice, Inbred Strains; Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine | 1996 |
The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Protein Conformation; S-Adenosylmethionine; Sequence Homology, Amino Acid; Vitamin B 12 | 1996 |
The essential yeast RNA binding protein Np13p is methylated.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Cattle; DNA Primers; Fungal Proteins; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Polymerase Chain Reaction; Protein-Arginine N-Methyltransferases; Recombinant Proteins; RNA-Binding Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion | 1996 |
Characterization of brain beta-carboline-2-N-methyltransferase, an enzyme that may play a role in idiopathic Parkinson's disease.
Topics: Animals; Brain; Carbolines; Cattle; Cytosol; Enzyme Inhibitors; Harmine; Humans; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Parkinson Disease; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1997 |
Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Female; Fetus; Leucovorin; Liver; Methionine; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Valproic Acid | 1996 |
Influence of osmotic stress on protein methylation in resealed erythrocytes.
Topics: Binding Sites; Biological Transport, Active; Erythrocytes; Humans; In Vitro Techniques; Membrane Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Osmotic Pressure; Ovalbumin; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Proteins; S-Adenosylmethionine | 1997 |
Suppression by phenobarbital of ethionine-induced hepatocellular carcinoma formation and hepatic S-adenosylethionine levels.
Topics: Adenosine; Animals; Body Weight; Ethionine; Liver; Liver Neoplasms; Male; Methylation; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1997 |
Detection and characterization of a protein isoaspartyl methyltransferase which becomes trapped in the extracellular space during blood vessel injury.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Detergents; Endothelium, Vascular; Extracellular Space; Female; Hydrogen-Ion Concentration; Intracellular Fluid; L-Lactate Dehydrogenase; Methylation; Muscle, Smooth; Ovalbumin; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Denaturation; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tissue Extracts; Tritium; Vena Cava, Inferior | 1997 |
Essential arginine residues in isoprenylcysteine protein carboxyl methyltransferase.
Topics: Adenosine; Animals; Arginine; Cell Membrane; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Male; Methylation; Phenylglyoxal; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Identification of a phenolic 3-O-methyltransferase in the lignin-degrading fungus Phanerochaete chrysosporium.
Topics: Basidiomycota; Lignin; Methylation; Methyltransferases; Phenols; S-Adenosylmethionine; Substrate Specificity; Vanillic Acid | 1997 |
Pancreatic exocrine secretion is blocked by inhibitors of methylation.
Topics: Acetylcysteine; Amylases; Animals; Antimetabolites; Cell Line; Enzyme Inhibitors; Ethionine; GTP-Binding Proteins; Male; Methylation; Methyltransferases; Pancreas; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Sincalide | 1997 |
Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.
Topics: Adenosine; Animals; Cell Differentiation; Cell-Free System; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Methionine; Methylation; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Processing, Post-Translational; Rats; S-Adenosylmethionine; Signal Transduction; Tritium | 1997 |
Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.
Topics: 3-O-Methylglucose; Acetylcysteine; Animals; Calcium; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Glucose; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Male; Methylation; Mycophenolic Acid; Peptides; Pertussis Toxin; Potassium; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Virulence Factors, Bordetella; Wasp Venoms | 1997 |
Binding of arsenicals to proteins in an in vitro methylation system.
Topics: Animals; Arsenicals; Arsenites; Chromatography, Gel; Cytosol; Glutathione; In Vitro Techniques; Liver; Male; Methylation; Protein Binding; Proteins; Rats; Rats, Inbred F344; S-Adenosylmethionine; Teratogens; Ultrafiltration | 1997 |
Metabolism of exogenous S-adenosylmethionine in isolated rat hepatocyte suspensions: methylation of plasma-membrane phospholipids without intracellular uptake.
Topics: Adenosine; Animals; Cells, Cultured; Humans; Kinetics; Liver; Liver Diseases; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
Novel evidence for an ecto-phospholipid methyltransferase in isolated rat hepatocytes.
Topics: Animals; Cell Membrane; Extracellular Space; Liver; Male; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine; Type C Phospholipases | 1998 |
Enzymatic methylation of arsenic compounds. V. Arsenite methyltransferase activity in tissues of mice.
Topics: Animals; Arsenicals; Arsenites; Biotransformation; Chromatography, Ion Exchange; Cytosol; Kidney; Liver; Lung; Male; Methylation; Methyltransferases; Mice; Organ Size; S-Adenosylmethionine; Sodium Compounds; Testis; Water Supply | 1998 |
Methionine synthase exists in two distinct conformations that differ in reactivity toward methyltetrahydrofolate, adenosylmethionine, and flavodoxin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkyl and Aryl Transferases; Binding, Competitive; Flavodoxin; Glycine; Histidine; Hydrolysis; Methylation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1998 |
Evidence for disturbed S-adenosylmethionine : S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?
Topics: Adult; Aged; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Models, Biological; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats.
Topics: Adenine; Animals; Body Weight; Cholesterol; Dietary Proteins; Fatty Acids; Linoleic Acid; Lipids; Liver; Male; Methionine; Methylation; Organ Size; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Wistar; S-Adenosylmethionine | 1998 |
Exogenous S-adenosyl-methionine methylates phospholipids located on the outer cell surface of isolated rat hepatocytes.
Topics: Adenosylhomocysteinase; Animals; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Hydrolases; Kinetics; Liver; Membrane Lipids; Methionine; Methylation; Phospholipids; Rats; S-Adenosylmethionine | 1998 |
S-adenosyl-L-methionine: role in phosphatidylcholine synthesis and in vitro effects on the ethanol-induced alterations of lipid metabolism.
Topics: Acetates; Carbon Radioisotopes; Esterification; Ethanol; Glycerol; Humans; Lipid Metabolism; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Triglycerides; Tritium; Tumor Cells, Cultured | 1998 |
Thiopurine S-methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate.
Topics: Alleles; Chromatography, High Pressure Liquid; Erythrocytes; Female; Genetic Variation; Heterozygote; Homozygote; Humans; Kinetics; Male; Methylation; Methyltransferases; Reproducibility of Results; S-Adenosylmethionine; Substrate Specificity; Thioguanine | 1998 |
The mechanism of adenosylmethionine-dependent activation of methionine synthase: a rapid kinetic analysis of intermediates in reductive methylation of Cob(II)alamin enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Aspartic Acid; Cobalt; Electron Transport; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1998 |
Transmethylation reactions and autoradiographic distribution of vitamin B12: effects of clioquinol treatment in mice.
Topics: Animals; Anti-Infective Agents, Local; Autoradiography; Brain; Chloroform; Clioquinol; Cobalt Radioisotopes; Kidney; Liver; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Scintillation Counting; Solubility; Tissue Distribution; Vitamin B 12; Water | 1998 |
Comparison in vitro of a high- and a low-abundance chemoreceptor of Escherichia coli: similar kinase activation but different methyl-accepting activities.
Topics: Bacterial Proteins; Chemoreceptor Cells; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Protein Kinases; Receptors, Cell Surface; S-Adenosylmethionine | 1998 |
Two intertwined methylation activities of the MmeI restriction-modification class-IIS system from Methylophilus methylotrophus.
Topics: Adenosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA, Bacterial; Gram-Negative Aerobic Bacteria; Methylation; Methyltransferases; S-Adenosylmethionine | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
S-Adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase.
Topics: Amino Acid Sequence; Cloning, Molecular; Humans; Methylation; Methyltransferases; Molecular Sequence Data; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid | 1999 |
Kinetics of S-adenosylmethionine cellular transport and protein methylation in Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
Topics: Animals; Biological Transport; Chromatography, High Pressure Liquid; Cytosol; Methylation; Proteins; S-Adenosylmethionine; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1999 |
Methylation of tea catechins by rat liver homogenates.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Liver; Magnetic Resonance Spectroscopy; Male; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Spectrometry, Mass, Fast Atom Bombardment; Tea | 1999 |
Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.
Topics: 5-Methylcytosine; Cloning, Molecular; Cytosine; Endoribonucleases; Escherichia coli; Gene Deletion; Hydroxymethyl and Formyl Transferases; Methylation; Methyltransferases; Ribonuclease T1; RNA, Ribosomal, 16S; S-Adenosylmethionine; Single-Strand Specific DNA and RNA Endonucleases; Substrate Specificity | 1999 |
Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat.
Topics: Animals; Carcinogens; Cell Division; DNA; Gene Expression; Isoenzymes; Liver; Male; Methionine Adenosyltransferase; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Thioacetamide | 1999 |
Modulation of tumor necrosis factor-alpha-mediated cytotoxicity by changes of the cellular methylation state: mechanism and in vivo relevance.
Topics: Animals; Cytotoxicity, Immunologic; Female; Membrane Potentials; Methylation; Methyltransferases; Mice; Mice, Nude; Mitochondria; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
New routes for lignin biosynthesis defined by biochemical characterization of recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent monooxygenase.
Topics: Arabidopsis; Arabidopsis Proteins; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Hydroxylation; Kinetics; Lignin; Methylation; Microsomes; Mixed Function Oxygenases; Plant Proteins; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Substrate Specificity | 1999 |
Biochemical analysis of myelin lipids and proteins in a model of methyl donor pathway deficit: effect of S-adenosylmethionine.
Topics: Animals; Animals, Suckling; Blotting, Western; Brain Chemistry; Butanes; Cycloleucine; Densitometry; Galactolipids; Glycolipids; Injections, Intraperitoneal; Methylation; Molecular Weight; Myelin Basic Protein; Myelin Sheath; Rats; S-Adenosylmethionine; Sciatic Nerve; Sphingomyelins; Sulfonic Acids | 1999 |
Methylation of cortical brain proteins from patients with HIV infection.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Encephalitis, Viral; HIV Infections; Humans; Male; Methylation; Middle Aged; Protein Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1999 |
What is SAMe? S-Adenosylmethionine.
Topics: Arthritis; Chronic Disease; Depression; Dietary Supplements; Health Education; Humans; Liver Diseases; Methylation; Nonprescription Drugs; S-Adenosylmethionine; United States | 1999 |
Rotavirus open cores catalyze 5'-capping and methylation of exogenous RNA: evidence that VP3 is a methyltransferase.
Topics: Acid Anhydride Hydrolases; Catalysis; Dinucleoside Phosphates; DNA-Directed RNA Polymerases; Guanosine Triphosphate; Methylation; Methyltransferases; Molecular Weight; RNA Caps; RNA, Viral; Rotavirus; S-Adenosylmethionine; Single-Strand Specific DNA and RNA Endonucleases; Ultraviolet Rays; Uridine Triphosphate; Viral Proteins | 1999 |
The biosynthesis of methylated amino acids in the active site region of methyl-coenzyme M reductase.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography, High Pressure Liquid; Chymotrypsin; Glutamine; Mass Spectrometry; Metalloporphyrins; Methane; Methanobacterium; Methionine; Methylation; Molecular Sequence Data; Molecular Structure; Oxidoreductases; Peptide Fragments; Protein Processing, Post-Translational; S-Adenosylmethionine; Sequence Analysis | 2000 |
PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells.
Topics: Animals; Arginine; Methylation; Mice; Mice, Mutant Strains; Oxidoreductases Acting on CH-NH Group Donors; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Rats; S-Adenosylmethionine | 2000 |
High-dose folic acid supplementation in rats: effects on gestation and the methionine cycle.
Topics: Animals; Dietary Supplements; Female; Fetal Weight; Folic Acid; Methionine; Methylation; Nutritional Status; Pregnancy; Pregnancy Outcome; Rats; Rats, Wistar; S-Adenosylmethionine | 2000 |
Methylation increases the open probability of the epithelial sodium channel in A6 epithelia.
Topics: Cell Line; Epithelial Cells; Epithelial Sodium Channels; Guanosine Triphosphate; Methylation; Methyltransferases; Mineralocorticoid Receptor Antagonists; S-Adenosylmethionine; Sodium Channels; Tubercidin | 2000 |
Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Consensus Sequence; Crystallography, X-Ray; Glycine; Glycine N-Methyltransferase; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 2000 |
An endogenous proteinacious inhibitor in porcine liver for S-adenosyl-L-methionine dependent methylation reactions: identification as oligosaccharide-linked acyl carrier protein.
Topics: Acyl Carrier Protein; Animals; Enzyme Inhibitors; Kinetics; Liver; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Weight; Oligosaccharides; Peptide Fragments; Protein Methyltransferases; Rats; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Transferases (Other Substituted Phosphate Groups) | 2000 |
Kinetics of methionine transport and metabolism by Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
Topics: Allosteric Regulation; Animals; Biological Transport; Cytosol; Humans; Kinetics; Methionine; Methylation; Protein Biosynthesis; Proteins; S-Adenosylmethionine; Sulfur; Thermodynamics; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2000 |
"Methylation-coupled" transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA.
Topics: DNA-Directed RNA Polymerases; Methylation; Reoviridae; RNA, Double-Stranded; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Transcription, Genetic | 1974 |
Identification of a methyltransferase from Mycobacterium smegmatis involved in glycopeptidolipid synthesis.
Topics: Amino Acid Sequence; Cell Wall; Conserved Sequence; Glycoconjugates; Methylation; Methyltransferases; Molecular Sequence Data; Multigene Family; Mycobacterium smegmatis; Open Reading Frames; Rhamnose; S-Adenosylmethionine; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
Effects of L-dopa treatment on methylation in mouse brain: implications for the side effects of L-dopa.
Topics: Animals; Antiparkinson Agents; Brain Chemistry; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Methionine Adenosyltransferase; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 2000 |
Alzheimer's disease revisited.
Topics: Aged; Aluminum; Alzheimer Disease; Biological Transport; Cell Membrane Permeability; Fatty Acids, Essential; Female; Humans; Male; Methylation; S-Adenosylmethionine | 2000 |
Analysis of isoaspartate in peptides and proteins without the use of radioisotopes.
Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Delta Sleep-Inducing Peptide; Methylation; Peptides; Protein Methyltransferases; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Time Factors | 2000 |
Increased methyl esterification of altered aspartyl residues in erythrocyte membrane proteins in response to oxidative stress.
Topics: Anion Exchange Protein 1, Erythrocyte; Ankyrins; Antioxidants; Ascorbic Acid; Aspartic Acid; Blood Proteins; Cell Membrane; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Hydrogen Peroxide; Malondialdehyde; Membrane Proteins; Methemoglobin; Methylation; Models, Biological; Neuropeptides; Oxidants; Oxidative Stress; Oxyhemoglobins; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; tert-Butylhydroperoxide; Time Factors; Vitamin E | 2000 |
Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase.
Topics: Animals; Cattle; Cytochrome c Group; Galactose; Genetic Complementation Test; Histones; Humans; Methylation; Methyltransferases; Mutagenesis; Myelin Basic Protein; Phenotype; Plasmids; Point Mutation; Precipitin Tests; Protein Kinases; Protein Methyltransferases; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays | 2000 |
Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, Gel; Cysteine; Freeze Drying; Male; Methylation; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Stereotyped Behavior; Sympathectomy, Chemical; Tremor | 2000 |
RNA methylation under heat shock control.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Bacterial Proteins; Caenorhabditis elegans; Crystallography, X-Ray; Escherichia coli; Heat-Shock Proteins; Humans; Methanococcus; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Protein Structure, Secondary; Recombinant Proteins; Ribosomes; RNA, Ribosomal, 23S; S-Adenosylmethionine; Schizosaccharomyces; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
Characterization of the AdoMet-dependent guanylyltransferase activity that is associated with the N terminus of bamboo mosaic virus replicase.
Topics: Amino Acid Sequence; Chromatography, Thin Layer; Guanosine Triphosphate; Methylation; Methyltransferases; Molecular Sequence Data; Nucleotidyltransferases; Plasmids; Poaceae; Potexvirus; Recombinant Proteins; RNA Caps; RNA-Dependent RNA Polymerase; S-Adenosylmethionine; Saccharomyces cerevisiae | 2001 |
Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer.
Topics: Animals; Cells, Cultured; Enzyme Inhibitors; Hepatocytes; Humans; Hydroxamic Acids; Isoenzymes; Liver Neoplasms; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; Rats; RNA, Messenger; S-Adenosylmethionine | 2001 |
Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110.
Topics: Bradyrhizobium; Chromatography, Thin Layer; Cyclization; Deuterium; Gas Chromatography-Mass Spectrometry; Lyases; Magnetic Resonance Spectroscopy; Methionine; Methylation; Phylogeny; Polyisoprenyl Phosphates; Rhodopseudomonas; S-Adenosylmethionine; Symbiosis; Triterpenes | 2001 |
Bacteria mediate methylation of iodine in marine and terrestrial environments.
Topics: Bacteria; Environmental Microbiology; Fresh Water; Hydrocarbons, Iodinated; Iodides; Iodine; Marine Biology; Methylation; Rhizobium; S-Adenosylmethionine; Water Microbiology | 2001 |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor.
Topics: Acetylation; Amino Acid Sequence; Animals; Arginine; Binding Sites; Cell Nucleus; HeLa Cells; Histones; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Methyltransferases; Molecular Sequence Data; Mutation; Oocytes; Protein-Arginine N-Methyltransferases; Receptors, Androgen; Recombinant Proteins; S-Adenosylmethionine; Transcriptional Activation; Xenopus | 2001 |
S-Adenosyl-L-methionine-dependent O-methylation of 2-hydroxy-3-alkylpyrazine in wine grapes: a putative final step of methoxypyrazine biosynthesis.
Topics: Chromatography, High Pressure Liquid; Fruit; Gas Chromatography-Mass Spectrometry; Methylation; Pyrazines; Rosales; S-Adenosylmethionine | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins.
Topics: Arginine; Binding Sites; HeLa Cells; Humans; Methylation; Models, Molecular; Myelin Basic Protein; Protein Conformation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; Recombinant Proteins; S-Adenosylmethionine | 2001 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine | 2001 |
Retinoid compounds activate and induce hepatic glycine N-methyltransferase in rats.
Topics: Animals; Enzyme Activation; Enzyme Induction; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tretinoin | 2001 |
Ca2+-antagonists inhibit the N-methyltransferase-dependent synthesis of phosphatidylcholine in the heart.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Dose-Response Relationship, Drug; Heart; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardium; Organ Culture Techniques; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Verapamil | 2001 |
Methylation is involved in the Ustilago maydis mating response.
Topics: Cyclic AMP; Ethionine; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Pheromones; Plants; Reproduction; S-Adenosylmethionine; Signal Transduction; Ustilago | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Activity of G gamma prenylcysteine carboxyl methyltransferase.
Topics: Animals; Cell Membrane; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Golgi Apparatus; Heterotrimeric GTP-Binding Proteins; Humans; Methylation; Protein Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Transfection | 2002 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; Arabidopsis; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydrolases; Methylation; Mutation; Pectins; Phenotype; Plants, Genetically Modified; S-Adenosylhomocysteine; S-Adenosylmethionine; Seeds | 2002 |
Enzymatic synthesis of [3'-O-methyl-(3)H]malvidin-3-glucoside from petunidin-3-glucoside.
Topics: Anthocyanins; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Glucosides; Isotope Labeling; Methylation; S-Adenosylmethionine; Tritium; Wine | 2002 |
Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.
Topics: Amino Acid Motifs; Autoantigens; Cell Nucleolus; Cold Temperature; Evolution, Molecular; Guanosine; Hydro-Lyases; Methylation; Methyltransferases; Microtubule-Associated Proteins; Nuclear Proteins; Phenotype; Protein Structure, Tertiary; Recombinant Fusion Proteins; Ribonucleoproteins, Small Nuclear; Ribonucleoproteins, Small Nucleolar; RNA Cap Analogs; RNA Caps; RNA Splicing; RNA-Binding Proteins; RNA, Fungal; RNA, Small Nuclear; RNA, Small Nucleolar; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Two-Hybrid System Techniques | 2002 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
Mutational analysis of conserved residues in HhaI DNA methyltransferase.
Topics: Binding Sites; Catalysis; Conserved Sequence; DNA; DNA Mutational Analysis; DNA-Cytosine Methylases; Enzyme Stability; Kinetics; Methylation; Models, Molecular; Mutagenesis, Site-Directed; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2002 |
Development of a strong cation-exchange high-performance liquid chromatography method for analysis of isoaspartate in proteins.
Topics: Cation Exchange Resins; Chromatography, High Pressure Liquid; Humans; Isoaspartic Acid; Methanol; Methylation; Peptide Fragments; Protein D-Aspartate-L-Isoaspartate Methyltransferase; S-Adenosylmethionine | 2002 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Topics: Animals; Cell Line; Cytoplasm; Deoxyribonucleotides; DNA; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Methylation; S-Adenosylmethionine; Tetrahydrofolates; Thymidine Monophosphate | 2002 |
Characterization of human soluble high and low activity catechol-O-methyltransferase catalyzed catechol estrogen methylation.
Topics: Base Sequence; Breast; Catalysis; Catechol O-Methyltransferase; Cloning, Molecular; Cytosol; DNA Primers; Epithelial Cells; Escherichia coli; Estrogens, Catechol; Female; Humans; Kinetics; Methylation; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Substrate Specificity | 2002 |
An essential role of s-adenosyl-L-methionine:L-methionine s-methyltransferase in selenium volatilization by plants. Methylation of selenomethionine to selenium-methyl-L-selenium- methionine, the precursor of volatile selenium.
Topics: Adaptation, Physiological; Arabidopsis; Base Sequence; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methylation; Methyltransferases; Molecular Sequence Data; Mutation; S-Adenosylmethionine; Selenium; Selenium Radioisotopes; Selenomethionine; Volatilization | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation.
Topics: Calorimetry; Escherichia coli; Humans; Indicators and Reagents; Kinetics; Methylation; Methyltransferases; Plasmids; Polylysine; Recombinant Proteins; S-Adenosylmethionine; Stereoisomerism; Sulfhydryl Compounds; Trinitrobenzenes | 2002 |
Cork taint of wines: role of the filamentous fungi isolated from cork in the formation of 2,4,6-trichloroanisole by o methylation of 2,4,6-trichlorophenol.
Topics: Anisoles; Biotransformation; Chlorophenols; Fungi; Methylation; Methyltransferases; Quercus; S-Adenosylmethionine; Trichoderma; Wine | 2002 |
Dose-dependent biotransformation of arsenite in rats--not S-adenosylmethionine depletion impairs arsenic methylation at high dose.
Topics: Adenosine Triphosphate; Animals; Arsenites; Bile; Biotransformation; Cacodylic Acid; Dose-Response Relationship, Drug; Glutathione; Kidney; Liver; Male; Methylation; Myocardium; Organometallic Compounds; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Functional analysis of BamHI DNA cytosine-N4 methyltransferase.
Topics: Catalytic Domain; Cytosine; DNA-Cytosine Methylases; Kinetics; Macromolecular Substances; Methylation; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity | 2003 |
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet.
Topics: Amino Acid Sequence; Animals; Binding Sites; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sequence Alignment | 2003 |
A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Topics: Amino Acid Sequence; Animals; Binding Sites; Dimerization; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutagenesis; Paramecium; Phycodnaviridae; Protein Conformation; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Homology, Amino Acid; Structural Homology, Protein; Substrate Specificity; Viral Proteins | 2003 |
Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio.
Topics: Amino Acids; Arabidopsis; Methylation; Methyltransferases; Mutagenesis, Insertional; S-Adenosylhomocysteine; S-Adenosylmethionine; Seeds; Sulfhydryl Compounds; Sulfur; Vitamin U; Zea mays | 2003 |
Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Crystallization; Crystallography, X-Ray; Drug Resistance, Bacterial; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Homology, Amino Acid; Streptomyces | 2003 |
Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols.
Topics: Binding, Competitive; Catalysis; Chromatography, Gel; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine max; Hydrocarbons; Kinetics; Methane; Methylation; Models, Chemical; Phenol; Phytosterols; S-Adenosylmethionine; Substrate Specificity; Time Factors; Triterpenes | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chlorocebus aethiops; Computational Biology; Conserved Sequence; COS Cells; DNA Primers; Homocysteine; Humans; Hydrolysis; Methylation; Methyltransferases; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylethanolamine N-Methyltransferase; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine; Transfection | 2003 |
L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients.
Topics: Adenosine Diphosphate; Aged; Arylsulfotransferase; Biotransformation; Blood Platelets; Carbidopa; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Drug Combinations; Erythrocytes; Female; Humans; Levodopa; Male; Methylation; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Sulfates | 2003 |
Enzymatic O-methylation of N-acetylserotonin to melatonin.
Topics: Acetylserotonin O-Methyltransferase; Melatonin; Methionine; Methylation; Pineal Gland; S-Adenosylmethionine; Serotonin; Transferases | 1960 |
[Enzymatic methylation of 2-hydroxy-estradiol-(17 beta) by a S-adenosylmethionine: acceptor-O-methyltransferase of rat liver].
Topics: Animals; Biochemical Phenomena; Estradiol; Liver; Methionine; Methylation; Methyltransferases; Nucleosides; Nucleotides; Rats; S-Adenosylmethionine; Transferases | 1962 |
Metabolism of thiopyrimidines and thiopurines. S-Methylation with S-adenosylmethionine transmethylase and catabolism in mammalian tissues.
Topics: Animals; Methylation; Methyltransferases; Purine Nucleosides; Purines; Pyrimidines; S-Adenosylmethionine; Transferases | 1963 |
Regulation of methylbenzoate emission after pollination in snapdragon and petunia flowers.
Topics: Antirrhinum; Benzoates; Benzoic Acid; DNA, Complementary; Ethylenes; Flowers; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methylation; Methyltransferases; Molecular Sequence Data; Odorants; Petunia; Plant Proteins; Reproduction; S-Adenosylmethionine; Sequence Analysis, DNA | 2003 |
Inhibition mechanism of S-adenosylmethionine-induced movement deficits by prenylcysteine analogs.
Topics: Amphetamine; Animals; Body Temperature; Central Nervous System Stimulants; Cystine; Drug Synergism; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Hyperkinesis; In Vitro Techniques; Male; Methylation; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Structure-Activity Relationship; Triazoles | 2003 |
Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Conserved Sequence; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phosphoprotein Phosphatases; Protein Folding; Protein Methyltransferases; Protein Phosphatase 2; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity | 2004 |
Critical residues for GTP methylation and formation of the covalent m7GMP-enzyme intermediate in the capping enzyme domain of bamboo mosaic virus.
Topics: Amino Acid Sequence; Guanosine Triphosphate; Methylation; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotidyltransferases; Potexvirus; RNA Cap Analogs; RNA Caps; RNA-Dependent RNA Polymerase; RNA, Viral; S-Adenosylmethionine; Sasa; Structure-Activity Relationship; Virus Replication | 2004 |
Structure and mechanism of mRNA cap (guanine-N7) methyltransferase.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Encephalitozoon cuniculi; Ligands; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Point Mutation; Protein Structure, Secondary; Protozoan Proteins; RNA Cap Analogs; RNA Caps; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Homology, Amino Acid; Static Electricity; Structure-Activity Relationship; Substrate Specificity | 2004 |
Rapid screening for S-adenosylmethionine-dependent methylation products by enzyme-transferred isotope patterns analysis.
Topics: Deuterium; Escherichia coli; Humans; Isotope Labeling; Methylation; Methyltransferases; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex | 2004 |
Influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line, Tumor; Cyclophilins; DNA Methylation; Down-Regulation; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methylation; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2004 |
Small molecule regulators of protein arginine methyltransferases.
Topics: Arginine; Binding Sites; Cell Line, Tumor; Cell Nucleus; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epitopes; Genes, Reporter; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Light; Luciferases; Luminescent Proteins; Lysine; Methylation; Models, Chemical; Nitrogen; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Transport; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Transfection; Ultraviolet Rays | 2004 |
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus.
Topics: Acyltransferases; Animals; Blotting, Western; Brain; Calbindin 2; Choline; Chromatography, High Pressure Liquid; Diet; DNA; Embryo, Mammalian; Female; Gene Deletion; Gene Expression Regulation, Developmental; Hippocampus; Histones; Liver; Male; Methylation; Methyltransferases; Mice; Mice, Knockout; Mitosis; Neurons; Phosphatidylethanolamine N-Methyltransferase; Pregnancy; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; S100 Calcium Binding Protein G; Stem Cells | 2004 |
O-Methylation of benzaldehyde derivatives by "lignin specific" caffeic acid 3-O-methyltransferase.
Topics: Amino Acid Substitution; Benzaldehydes; Carbon Radioisotopes; Down-Regulation; Hydroxybenzoates; Kinetics; Lignin; Medicago sativa; Methylation; Methyltransferases; Phenols; Plant Stems; Plants, Genetically Modified; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity | 2004 |
The inhibitory role of methylation on the binding characteristics of dopamine receptors and transporter.
Topics: Analysis of Variance; Animals; Benzamides; Benzazepines; Binding, Competitive; Brain; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methylation; Nerve Tissue Proteins; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; S-Adenosylmethionine; Tissue Distribution; Tritium | 2004 |
An origin for arsenobetaine involving bacterial formation of an arsenic-carbon bond.
Topics: Acetates; Arsenic; Arsenicals; Carbon; Methylation; Pseudomonas; S-Adenosylmethionine | 2004 |
Techniques in protein methylation.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; DNA-Binding Proteins; Enzyme Inhibitors; Glutathione Transferase; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Poly(A)-Binding Protein I; Precipitin Tests; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; RNA-Binding Proteins; S-Adenosylmethionine; Signal Transduction; Substrate Specificity | 2004 |
N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.
Topics: Amino Acid Sequence; Archaea; Calorimetry, Differential Scanning; Catalysis; Catalytic Domain; Chromatography, Gel; Databases as Topic; DNA Methylation; Electrophoresis, Polyacrylamide Gel; Eukaryotic Cells; Guanosine; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; RNA; RNA, Transfer; S-Adenosylmethionine; Sequence Homology, Amino Acid; Temperature; Time Factors; tRNA Methyltransferases | 2004 |
The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro.
Topics: Biochemical Phenomena; Biochemistry; Catalysis; Gene Deletion; In Vitro Techniques; Methylation; Methyltransferases; Models, Biological; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Time Factors | 2004 |
Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine.
Topics: Adult; Aged; Case-Control Studies; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 2004 |
Structural and thermodynamic evidence for a stabilizing role of Nop5p in S-adenosyl-L-methionine binding to fibrillarin.
Topics: Archaeal Proteins; Archaeoglobales; Binding Sites; Calorimetry; Chromosomal Proteins, Non-Histone; Crystallography, X-Ray; Hydrogen Bonding; Methylation; Nuclear Proteins; Protein Binding; Ribonucleoproteins; S-Adenosylmethionine; Thermodynamics | 2004 |
DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cloning, Molecular; Humans; Lung Neoplasms; Membrane Proteins; Methylation; Microfilament Proteins; Protein-Arginine N-Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Tumor Suppressor Proteins | 2004 |
Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes.
Topics: Anti-Bacterial Agents; Methylation; S-Adenosylmethionine; Streptomycetaceae | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).
Topics: Chromatography, Thin Layer; Dithiothreitol; DNA Methylation; DNA, Complementary; Dose-Response Relationship, Drug; Guanine; Guanosine; Guanosine Diphosphate; Methylation; Methyltransferases; Protein Binding; Recombinant Proteins; RNA; RNA, Small Nucleolar; S-Adenosylmethionine; Schizosaccharomyces; Time Factors | 2005 |
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid | 2005 |
Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.
Topics: Adenosine; Animals; Binding Sites; Crystallization; Encephalitozoon cuniculi; Enzyme Inhibitors; Guanosine Triphosphate; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Models, Molecular; Molecular Structure; Mutagenesis; Mutation, Missense; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2005 |
Saturation transfer difference measurements with SU(VAR)3-9 and S-adenosyl-L-methionine.
Topics: Animals; Binding Sites; Drosophila melanogaster; Drosophila Proteins; In Vitro Techniques; Kinetics; Methylation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Repressor Proteins; S-Adenosylmethionine | 2005 |
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase.
Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Ligands; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Conformation; Protein Footprinting; RNA-Binding Proteins; RNA, Transfer, Leu; S-Adenosylmethionine; Sequence Alignment; Thermotoga maritima; tRNA Methyltransferases | 2005 |
Regulation of trehalose metabolism by Adox and AdoMet in Saccharomyces cerevisiae.
Topics: Adenosine; Glucosyltransferases; Methylation; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trehalase; Trehalose | 2005 |
The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Dopamine; Lysophosphatidylcholines; Methylation; MPTP Poisoning; PC12 Cells; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
S-adenosylhomocysteine metabolism in different cell lines: effect of hypoxia and cell density.
Topics: Adenosylhomocysteinase; Anaerobiosis; Cell Count; Cell Hypoxia; Cell Line; Cell Survival; Energy Metabolism; Humans; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Cell Membrane; Cell-Free System; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Hydrolysis; Leptospira interrogans; Lipid A; Lipids; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Phosphates; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Methyltransferases; Protein Structure, Tertiary; Receptors, Cell Surface; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors | 2005 |
o-nitrobenzenesulfonamides in nucleoside synthesis: efficient 5'-aziridination of adenosine.
Topics: Adenosine; Aziridines; DNA Nucleotidylexotransferase; Methylation; Methyltransferases; Molecular Mimicry; Mustard Plant; Nitrobenzenes; Nucleosides; S-Adenosylmethionine; Spectrum Analysis; Sulfonamides | 2005 |
Effect of fasting on methionine adenosyltransferase expression and the methionine cycle in the mouse liver.
Topics: Animals; DNA Methylation; Fasting; Gene Expression; Glutathione; Kinetics; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Mice; RNA, Messenger; S-Adenosylmethionine | 2005 |
The transmethylation cycle in the brain of Alzheimer patients.
Topics: Aged; Alzheimer Disease; Brain; Chromatography, High Pressure Liquid; Female; Humans; Male; Mass Spectrometry; Membrane Proteins; Methylation; Middle Aged; Presenilin-1; Promoter Regions, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 2005 |
In nucleo enzymatic assays for the identification and characterization of histone modifying activities.
Topics: Acetyl Coenzyme A; Acetylation; Adenosine Triphosphate; Animals; Cell Fractionation; Cell Line; Cell Nucleus; Clinical Laboratory Techniques; Enzymes; Histones; Humans; Methylation; Phosphorylation; Protein Processing, Post-Translational; Radioisotopes; S-Adenosylmethionine; Yeasts | 2005 |
Inhibitory effect of Epimedium extract on S-adenosyl-L-homocysteine hydrolase and biomethylation.
Topics: Adenosylhomocysteinase; Algorithms; Cell Line, Tumor; Enzyme Inhibitors; Epimedium; Flavones; Glutathione; Humans; Liver; Methylation; Plant Extracts; Recombinant Proteins; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Catalysis; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Kinetics; Methylation; Mice; Peptide Fragments; Phosphorylation; Protein Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 2005 |
In vitro and in vivo analysis of the major type I protein arginine methyltransferase from Trypanosoma brucei.
Topics: Amino Acid Sequence; Animals; Methylation; Molecular Sequence Data; Protein-Arginine N-Methyltransferases; Protozoan Proteins; RNA; RNA-Binding Proteins; RNA, Mitochondrial; RNA, Protozoan; S-Adenosylmethionine; Sequence Alignment; Substrate Specificity; Trypanosoma brucei brucei | 2005 |
A deficiency in S-adenosylmethionine synthetase interrupts assembly of the septal ring in Escherichia coli K-12.
Topics: Anti-Bacterial Agents; Aztreonam; Cell Cycle Proteins; Cell Division; Cytoskeleton; Escherichia coli K12; Escherichia coli Proteins; Membrane Proteins; Methionine Adenosyltransferase; Methylation; Recombinant Fusion Proteins; S-Adenosylmethionine | 2005 |
Is it time to reevaluate methyl balance in humans?
Topics: Animals; Creatine; Creatinine; Diet; Humans; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2006 |
Chemical expansion of cofactor activity.
Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates | 2006 |
Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase.
Topics: Arsenic; Arsenicals; Arsenites; Cloning, Molecular; Drug Resistance; Escherichia coli; Gene Expression Regulation, Bacterial; Inactivation, Metabolic; Methylation; Methyltransferases; Rhodopseudomonas; S-Adenosylmethionine; Transcription, Genetic; Volatilization | 2006 |
Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Catalytic Domain; Cell Line; Chromatin; Coenzymes; Dose-Response Relationship, Drug; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Methyltransferases; Models, Biological; Molecular Sequence Data; Peptides; Protein Methyltransferases; Recombinant Proteins; Repressor Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Spodoptera; Substrate Specificity; Time Factors | 2006 |
S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.
Topics: Adenosine; Antiviral Agents; Betaine; Cell Line; DNA; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Methylation; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; STAT1 Transcription Factor; Virus Replication | 2006 |
Phospholipid methylation in skeletal muscle membranes.
Topics: Animals; Cell Membrane; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Drug Interactions; Male; Methylation; Muscle, Skeletal; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phospholipids; Rats; Rats, Sprague-Dawley; Reaction Time; S-Adenosylmethionine; Subcellular Fractions; Tritium | 1985 |
Crystal structures of BchU, a methyltransferase involved in bacteriochlorophyll c biosynthesis, and its complex with S-adenosylhomocysteine: implications for reaction mechanism.
Topics: Amino Acid Sequence; Bacterial Proteins; Bacteriochlorophylls; Binding Sites; Chlorobium; Crystallography, X-Ray; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Alignment; Substrate Specificity; Tetrapyrroles; Zinc | 2006 |
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.
Topics: Adolescent; Autistic Disorder; Catechol O-Methyltransferase; Child; Child, Preschool; DNA Primers; Female; Gene Frequency; Glutathione Transferase; Humans; Male; Membrane Transport Proteins; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Reduced Folate Carrier Protein; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosylhomocysteinase; Apoptosis; Caspase Inhibitors; Caspases; Dipyridamole; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Humans; Methylation; Nucleoside Transport Proteins; Oligonucleotide Array Sequence Analysis; Pentostatin; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Topics: Amino Acid Sequence; Binding Sites; Biological Evolution; Biotransformation; Crystallography, X-Ray; Immunity, Innate; Medicago truncatula; Methylation; Methyltransferases; Molecular Sequence Data; Phenols; Plant Diseases; Plant Proteins; Protein Structure, Secondary; Pterocarpans; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2006 |
Methyl balance and transmethylation fluxes in humans.
Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2007 |
Crystal structures of CbiL, a methyltransferase involved in anaerobic vitamin B biosynthesis, and CbiL in complex with S-adenosylhomocysteine--implications for the reaction mechanism.
Topics: Amino Acid Sequence; Bacterial Proteins; Chlorobium; Cobalt; Crystallography, X-Ray; Methylation; Methyltransferases; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity; Vitamin B Complex | 2007 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Abnormal folate metabolism in foetuses affected by neural tube defects.
Topics: Anencephaly; Animals; Antimetabolites; Deoxyuridine; Female; Ferredoxin-NADP Reductase; Fetal Diseases; Fetus; Fibroblasts; Folic Acid; Genotype; Humans; Methylation; Mice; Neural Tube Defects; NIH 3T3 Cells; Polymorphism, Genetic; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Dysraphism | 2007 |
Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.
Topics: Adenine Nucleotides; Adenosine; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Chelating Agents; Culture Media; Edetic Acid; Humans; Inosine; Kinetics; Liver Neoplasms; Methylation; S-Adenosylmethionine; Time Factors; Trypsin | 2007 |
Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs.
Topics: Archaeal Proteins; Archaeoglobus fulgidus; Catalytic Domain; Chromosomal Proteins, Non-Histone; Crystallography, X-Ray; Methylation; Nuclear Proteins; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrococcus furiosus; Ribonucleoproteins; RNA; S-Adenosylmethionine | 2007 |
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Enzyme Activation; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Temperature; Thermotoga maritima; Vitamin B 12 | 2007 |
S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase.
Topics: Animals; Catechol O-Methyltransferase; Cytosol; Methylation; Mice; Organ Specificity; Protein Processing, Post-Translational; Recombinant Proteins; S-Adenosylmethionine; Swine; Tyrphostins | 2007 |
The import of S-adenosylmethionine into the Golgi apparatus is required for the methylation of homogalacturonan.
Topics: Biological Transport; Golgi Apparatus; Methylation; Pectins; Pisum sativum; S-Adenosylmethionine; Time Factors | 2007 |
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cytidine; Dimerization; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Methylation; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrococcus horikoshii; Recombinant Proteins; RNA, Archaeal; RNA, Transfer; S-Adenosylmethionine; Sequence Homology, Amino Acid; tRNA Methyltransferases | 2008 |
Continuous enzymatic assay for histone lysine methyltransferases.
Topics: Biological Assay; Histone-Lysine N-Methyltransferase; Kinetics; Methylation; Neurospora crassa; Peptides; Reproducibility of Results; S-Adenosylmethionine | 2007 |
Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Catalysis; Ethanolamines; Genetic Complementation Test; Humans; Malaria, Falciparum; Methylation; Methyltransferases; Mutation, Missense; Phosphatidylcholines; Plasmodium falciparum; Protozoan Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae | 2008 |
Metabolic labeling of prenyl and carboxyl-methyl groups.
Topics: Animals; Cells, Cultured; Humans; Indicators and Reagents; Isotope Labeling; Methionine; Methylation; Mevalonic Acid; Protein O-Methyltransferase; Protein Prenylation; Protein Processing, Post-Translational; Proteins; S-Adenosylmethionine; Tritium | 2001 |
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc | 2008 |
A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism.
Topics: Arginine; Humans; Kinetics; Methylation; Nuclear Proteins; Peptides; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 2008 |
Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice.
Topics: Acetylation; Animals; Carcinogens; Cell Fractionation; Cell Nucleus; Disease Models, Animal; Drug Antagonism; Drug Combinations; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hepatocytes; Histones; Liver; Male; Methylation; Mice; Mice, Inbred C3H; Oligonucleotide Array Sequence Analysis; Proteins; RNA, Messenger; S-Adenosylmethionine | 2008 |
West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism.
Topics: Binding Sites; Crystallography, X-Ray; Guanosine Triphosphate; Methylation; Methyltransferases; RNA Caps; S-Adenosylmethionine; West Nile virus | 2008 |
Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases.
Topics: Chromatin; Histone-Lysine N-Methyltransferase; Lysine; Methylation; Models, Molecular; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation.
Topics: Animals; Chromatin; DNA Primers; Gene Expression; Histones; Lipopolysaccharides; Male; Methylation; Mice; Mice, Inbred C57BL; Monocytes; Polymerase Chain Reaction; RNA; S-Adenosylmethionine; Transfection; Tumor Necrosis Factor-alpha | 2008 |
S-Adenosyl-l-methionine activates the cardiac ryanodine receptor.
Topics: Adenosine Triphosphate; Animals; Heart; Methylation; Ryanodine; Ryanodine Receptor Calcium Release Channel; S-Adenosylmethionine | 2008 |
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.
Topics: Actinobacteria; Amino Acid Sequence; Camphanes; Conserved Sequence; Cyclization; Diphosphates; Diterpenes; Escherichia coli; Genes, Bacterial; Intramolecular Lyases; Markov Chains; Methylation; Methyltransferases; Molecular Sequence Data; Phylogeny; Recombinant Proteins; S-Adenosylmethionine; Sequence Alignment; Sequence Analysis, Protein; Terpenes | 2008 |
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
Topics: Catalysis; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Quantum Theory; S-Adenosylhomocysteine; S-Adenosylmethionine; Static Electricity; Substrate Specificity | 2008 |
Reduced brain choline in homocystinuria due to remethylation defects.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Chemistry; Child; Child, Preschool; Choline; Choline Deficiency; Creatine; Female; Homocysteine S-Methyltransferase; Homocystinuria; Humans; Magnetic Resonance Spectroscopy; Male; Methylation; S-Adenosylmethionine | 2008 |
Maternal global methylation status and risk of congenital heart diseases.
Topics: Adult; Biomarkers; Case-Control Studies; Child; Down Syndrome; Female; Heart; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Linear Models; Methylation; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Topics: Animals; Diet; DNA-Binding Proteins; Food; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Methionine; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; S-Adenosylmethionine; Transcription Factors | 2008 |
Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Survival; Corpus Striatum; Formaldehyde; Formates; Male; Methanol; Methylation; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tyrosine 3-Monooxygenase | 2008 |
The divergent eukaryote Trichomonas vaginalis has an m7G cap methyltransferase capable of a single N2 methylation.
Topics: Animals; Giardia lamblia; Guanine Nucleotides; Methylation; Methyltransferases; Models, Molecular; Protozoan Proteins; RNA Cap Analogs; S-Adenosylmethionine; Substrate Specificity; Trichomonas vaginalis | 2008 |
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.
Topics: Cell Line; Cells, Cultured; Disulfides; Epithelial Cells; Humans; Lung; Metabolic Networks and Pathways; Methionine; Methylation; Methyltransferases; Models, Biological; Oxidation-Reduction; Oxidative Stress; Peroxides; Respiratory Mucosa; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.
Topics: Autistic Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Glutathione; Humans; Leucovorin; Male; Methylation; Nutritional Status; Oxidation-Reduction; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
Scintillation proximity assay for measurement of RNA methylation.
Topics: Centrifugation; Enzyme Inhibitors; Kinetics; Methylation; Methyltransferases; Ribosome Subunits, Small, Bacterial; RNA; S-Adenosylmethionine; Scintillation Counting | 2009 |
Analysis of the Arabidopsis floral proteome: detection of over 2 000 proteins and evidence for posttranslational modifications.
Topics: Arabidopsis; Arabidopsis Proteins; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Flowers; Mass Spectrometry; Methylation; Phylogeny; Protein Processing, Post-Translational; Proteome; RNA, Messenger; S-Adenosylmethionine | 2009 |
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.
Topics: Analysis of Variance; Animal Feed; Animals; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Female; Homocystine; Hyperhomocysteinemia; Kidney; Liver; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Statistics, Nonparametric; Tissue Distribution | 2009 |
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4.
Topics: Carbon Dioxide; Catalytic Domain; Mass Spectrometry; Methylation; Models, Molecular; Nucleosides; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Protein Structure, Tertiary; RNA, Transfer, Phe; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; tRNA Methyltransferases | 2009 |
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Humans; Methylation; Methyltransferases; Models, Molecular; Peptide Fragments; Protein Binding; Protein Conformation; Protein Structure, Tertiary; RNA Cap Analogs; RNA Caps; RNA Processing, Post-Transcriptional; S-Adenosylmethionine | 2009 |
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA.
Topics: Amino Acid Sequence; Bacteria; Bacterial Proteins; Base Sequence; Biocatalysis; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guanine; Kinetics; Mass Spectrometry; Methylation; Microbial Viability; Models, Biological; Molecular Sequence Data; Mutant Proteins; Nucleic Acid Conformation; Recombinant Proteins; RNA, Messenger; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 2009 |
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.
Topics: Animals; Antioxidants; Cysteine; Gas Chromatography-Mass Spectrometry; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Thioctic Acid | 2009 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Sources of S-adenosyl-L-homocysteine background in measuring protein arginine N-methyltransferase activity using tandem mass spectrometry.
Topics: Artifacts; Chromatography, Liquid; Enzyme Assays; Humans; Mass Spectrometry; Methylation; Protein-Arginine N-Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2010 |
A fast and efficient method for quantitative measurement of S-adenosyl-L-methionine-dependent methyltransferase activity with protein substrates.
Topics: Enzyme Assays; Humans; Kinetics; Methylation; Methyltransferases; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Proteins; S-Adenosylmethionine; Time Factors; Tritium | 2010 |
Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n).
Topics: Dengue Virus; Enzyme Inhibitors; Kinetics; Methylation; Methyltransferases; Models, Molecular; Oligonucleotides; Protein Structure, Tertiary; RNA Caps; S-Adenosylmethionine; Viral Nonstructural Proteins | 2010 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Biochemical control of CARM1 enzymatic activity by phosphorylation.
Topics: Animals; Binding Sites; Cell Line; Crystallography, X-Ray; Histones; Humans; Hydrogen Bonding; Methylation; Mice; Mitosis; p300-CBP Transcription Factors; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2009 |
Inhibition of STAT1 methylation is involved in the resistance of hepatitis B virus to Interferon alpha.
Topics: Cell Line; Hepatitis B virus; Hepatocytes; Humans; Immunoprecipitation; Interferon-alpha; Methylation; Phosphorylation; Protein Binding; Protein Inhibitors of Activated STAT; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; STAT1 Transcription Factor | 2010 |
Biocatalytic Friedel-Crafts alkylation using non-natural cofactors.
Topics: Alkylation; Catalysis; Green Chemistry Technology; Methylation; Methyltransferases; Organic Chemistry Phenomena; S-Adenosylmethionine | 2009 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
S-adenosyl-L-methionine restores photoreceptor function following acute retinal ischemia.
Topics: Acute Disease; Administration, Oral; Animals; Blindness; Creatine; Electroretinography; Female; Humans; Injections, Intraocular; Intraocular Pressure; Ischemia; Membrane Transport Proteins; Methylation; Photoreceptor Cells, Vertebrate; Rats; Reperfusion Injury; Retinal Vessels; S-Adenosylmethionine; Time Factors | 2009 |
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.
Topics: Amino Acid Sequence; Bacterial Proteins; Drug Resistance, Bacterial; Evolution, Molecular; Ligands; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phylogeny; RNA, Ribosomal, 23S; S-Adenosylmethionine; Sequence Homology, Amino Acid | 2010 |
Impaired methylation as a novel mechanism for proteasome suppression in liver cells.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chymotrypsin; Ethanol; Humans; Liver; Methylation; Mice; Mice, Inbred C57BL; Proteasome Endopeptidase Complex; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 2010 |
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Topics: 3' Untranslated Regions; Animals; Antigens, Surface; Binding Sites; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; ELAV Proteins; ELAV-Like Protein 1; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Glycine N-Methyltransferase; Half-Life; Hepatocytes; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; RNA Interference; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transfection | 2010 |
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Calorimetry; Catalytic Domain; Conserved Sequence; Drug Resistance, Bacterial; Methylation; Methyltransferases; Micromonospora; Models, Molecular; Molecular Sequence Data; Ribosome Subunits, Small, Bacterial; RNA, Ribosomal, 16S; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Homology, Amino Acid | 2010 |
Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.
Topics: Histone-Lysine N-Methyltransferase; Humans; Inhibitory Concentration 50; Methylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Substrate Specificity | 2010 |
The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.
Topics: Animal Nutritional Physiological Phenomena; Animals; Disease Models, Animal; Ethanol; Gene Expression; Histones; Liver; Liver Diseases, Alcoholic; Male; Methylation; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; S-Adenosylmethionine | 2010 |
Regulation of homocysteine metabolism and methylation in human and mouse tissues.
Topics: Animals; Computational Biology; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus.
Topics: Adenosine; Animals; Dengue Virus; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Methylation; Methyltransferases; RNA; S-Adenosylmethionine; Viral Proteins | 2010 |
S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet.
Topics: Animals; Diet; Dietary Supplements; Erythrocytes; Glutathione; Glutathione Transferase; Homocysteine; Lipid Peroxidation; Methylation; Mice; Oxidative Stress; S-Adenosylmethionine; Superoxide Dismutase; Vitamin B Deficiency | 2010 |
Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain.
Topics: Amino Acid Sequence; Animals; Brain; Catalysis; Eukaryotic Initiation Factors; Humans; Isoaspartic Acid; Mechanistic Target of Rapamycin Complex 1; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Multiprotein Complexes; Protein Binding; Protein Biosynthesis; Proteins; Recombinant Proteins; S-Adenosylmethionine; TOR Serine-Threonine Kinases; Transcription Factors | 2010 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2011 |
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.
Topics: Animals; Carbon; DNA-Binding Proteins; Female; Fibroblasts; Folic Acid; Folic Acid Deficiency; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Mutant Strains; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine Monophosphate; Transcription Factors | 2010 |
New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT).
Topics: Arsenites; Disulfides; Glutathione; Humans; Kinetics; Methylation; Methyltransferases; S-Adenosylmethionine; Spectrum Analysis | 2010 |
Possible regulation of trehalose metabolism by methylation in Saccharomyces cerevisiae.
Topics: Adenosine; Cell Proliferation; Gene Expression Regulation, Fungal; Hydrogen-Ion Concentration; Methylation; Protein Processing, Post-Translational; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Trehalose | 2011 |
Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis.
Topics: Amino Acid Sequence; Binding, Competitive; Drug Evaluation, Preclinical; Electrophoresis, Capillary; Enzyme Assays; Histone Demethylases; Histone-Lysine N-Methyltransferase; Kinetics; Methylation; Microfluidic Analytical Techniques; Molecular Sequence Data; Peptides; S-Adenosylmethionine; Small Molecule Libraries | 2010 |
Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.
Topics: Bioengineering; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Crystallography, X-Ray; Dipeptides; Esterification; Fosfomycin; Kinetics; Mass Spectrometry; Methylation; Methyltransferases; Molecular Structure; Organophosphonates; S-Adenosylmethionine; Streptomyces; Substrate Specificity | 2010 |
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.
Topics: Base Sequence; Cell Nucleolus; Dimerization; Fetal Growth Retardation; Humans; Methanococcales; Methylation; Methyltransferases; Molecular Sequence Data; Nuclear Proteins; Point Mutation; Pseudouridine; Psychomotor Disorders; Ribosomal Proteins; Ribosomes; RNA, Ribosomal, 18S; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2011 |
Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.
Topics: Catalysis; Catalytic Domain; Methanococcus; Methylation; Models, Biological; Models, Molecular; Molecular Conformation; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2010 |
Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases.
Topics: Archaea; Methylation; Methyltransferases; Pyrococcus abyssi; Recombinant Proteins; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Uridine | 2011 |
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Topics: Adenine; Base Sequence; Escherichia coli; Escherichia coli Proteins; Humans; Kanamycin Resistance; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Footprinting; Ribosome Subunits, Small, Bacterial; RNA, Ribosomal, 16S; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
O-carboxyl- and N-methyltransferases active on plant aquaporins.
Topics: Amino Acid Sequence; Aquaporins; Arabidopsis; Arabidopsis Proteins; Biological Transport; Methylation; Molecular Sequence Data; Peptides; Phylogeny; Plants, Genetically Modified; Protein Methyltransferases; Protein O-Methyltransferase; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity | 2010 |
An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.
Topics: Binding Sites; DNA-Binding Proteins; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunoprecipitation; Lysine; Methylation; Methyltransferases; Models, Biological; Mutation; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Protein Binding; Protein Multimerization; RNA Interference; S-Adenosylmethionine; Substrate Specificity; Transcription Factors | 2010 |
QM/MM free energy simulations of salicylic acid methyltransferase: effects of stabilization of TS-like structures on substrate specificity.
Topics: Binding Sites; Catalysis; Clarkia; Computer Simulation; Methylation; Methyltransferases; Models, Molecular; Parabens; Plant Immunity; Plant Proteins; Protein Binding; Protein Engineering; S-Adenosylmethionine; Salicylates; Salicylic Acid; Substrate Specificity; Thermodynamics | 2011 |
Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome.
Topics: Adolescent; Carrier Proteins; Cell Line, Transformed; Child; Child, Preschool; Cytosol; Down Syndrome; Glutathione; Humans; Infant; Methylation; Mitochondria; S-Adenosylmethionine | 2011 |
Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.
Topics: Amino Acid Sequence; Catalytic Domain; Clostridium thermocellum; Crystallography, X-Ray; DNA Primers; Manganese; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Recombinant Proteins; Ribose; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity | 2011 |
S-adenosyl-L-methionine induces compaction of nascent peptide chain inside the ribosomal exit tunnel upon translation arrest in the Arabidopsis CGS1 gene.
Topics: Amino Acid Sequence; Arabidopsis Proteins; Genes, Plant; Methylation; Peptides; Protein Biosynthesis; Ribosomes; RNA, Messenger; S-Adenosylmethionine | 2011 |
RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift.
Topics: Alkenes; Base Sequence; Chromatography, High Pressure Liquid; DNA Primers; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Polymerase Chain Reaction; RNA, Bacterial; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization | 2011 |
The C. elegans PRMT-3 possesses a type III protein arginine methyltransferase activity.
Topics: Animals; Biocatalysis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Histones; Humans; Methylation; Methyltransferases; omega-N-Methylarginine; Phylogeny; Protein Binding; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Sequence Homology, Amino Acid | 2011 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.
Topics: Adenosine; Bacterial Proteins; Biocatalysis; Carbon; Chemical Phenomena; Cysteine; Escherichia coli; Escherichia coli Proteins; Hydrogen; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus | 2011 |
Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.
Topics: Amino Acid Substitution; Animals; Base Sequence; Catalytic Domain; Cysteine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Humans; In Vitro Techniques; Kinetics; Methylation; Mice; Models, Molecular; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 2011 |
Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase.
Topics: Amides; Binding Sites; Carrier Proteins; Coenzymes; Cyclization; Cyclosporine; Enzyme Inhibitors; Hydrogen Bonding; Methylation; Methyltransferases; Models, Molecular; Multienzyme Complexes; Peptide Synthases; Protein Binding; Protein Structure, Tertiary; S-Adenosylmethionine; Substrate Specificity | 2011 |
High bone concentrations of homocysteine are associated with altered bone morphology in humans.
Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Collagen; Extracellular Matrix; Female; Femur; Hip; Homocysteine; Humans; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Structural basis for methyl transfer by a radical SAM enzyme.
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Hydrogen Bonding; Methylation; Methyltransferases; Models, Molecular; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine | 2011 |
Biochemistry. The two faces of SAM.
Topics: Adenine; Adenosine; Bacterial Proteins; Biocatalysis; Catalytic Domain; Chemical Phenomena; Cysteine; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus | 2011 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Modeling a new water channel that allows SET9 to dimethylate p53.
Topics: Catalysis; Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Tumor Suppressor Protein p53; Water | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors.
Topics: Coenzymes; High-Throughput Screening Assays; Humans; Luminescent Measurements; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2011 |
Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus.
Topics: Bacterial Proteins; Bacteroides; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Bacterial; Humans; Intestines; Methylation; Methyltransferases; Protein Folding; Protein Structure, Secondary; S-Adenosylhomocysteine; S-Adenosylmethionine; Ubiquinone | 2011 |
Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast.
Topics: Amino Acid Substitution; Basic-Leucine Zipper Transcription Factors; Cell Membrane; Gene Expression Profiling; Gene Expression Regulation, Fungal; Gene Knockout Techniques; Methionine; Methylation; Mutation; Myo-Inositol-1-Phosphate Synthase; Nuclear Proteins; Phospholipids; Polymorphism, Single Nucleotide; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Transcription, Genetic | 2011 |
Dual role of S-adenosylmethionine (SAM+) in the methylation of sp2-hybridized electrophilic carbons.
Topics: Chemistry, Organic; Methylation; S-Adenosylmethionine | 2011 |
Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.
Topics: Arginine; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Epigenesis, Genetic; Escherichia coli; Humans; Methylation; Models, Molecular; Molecular Weight; Plasmids; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; Repressor Proteins; S-Adenosylmethionine; Substrate Specificity; Transformation, Bacterial | 2011 |
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Topics: Crystallography, X-Ray; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; RNA Cap Analogs; RNA Caps; RNA, Viral; S-Adenosylmethionine; Severe acute respiratory syndrome-related coronavirus; Viral Nonstructural Proteins | 2011 |
Synthesis of an azide-bearing N-mustard analogue of S-adenosyl-L-methionine.
Topics: Alkylation; Azides; Chemistry Techniques, Synthetic; Deoxyadenosines; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Humans; Methylation; Molecular Probes; Mustard Compounds; Ribose; S-Adenosylmethionine | 2011 |
Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies.
Topics: Animals; Catechin; Catechol O-Methyltransferase; Computer Simulation; Cytosol; Female; Humans; Liver; Methylation; Models, Molecular; Molecular Structure; Placenta; Pregnancy; Pregnancy Proteins; Proanthocyanidins; Rats; Rats, Wistar; S-Adenosylmethionine; Species Specificity; Substrate Specificity | 2012 |
RAM/Fam103a1 is required for mRNA cap methylation.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Cell Survival; Conserved Sequence; Gene Expression Regulation; Guanosine; HEK293 Cells; Humans; Immunoprecipitation; Methylation; Methyltransferases; Molecular Sequence Data; Nuclear Proteins; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; RNA Caps; RNA-Binding Proteins; S-Adenosylmethionine; Sequence Alignment | 2011 |
Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.
Topics: Cell Membrane; Crystallography, X-Ray; Cytosol; Lipid Metabolism; Methanosarcina; Methylation; Models, Molecular; Mutation; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2011 |
The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus.
Topics: Hydroxybenzoates; Lipid Metabolism; Methylation; Methyltransferases; Phenols; Recombinant Proteins; S-Adenosylmethionine; Streptomyces griseus; Streptomyces lividans; Substrate Specificity | 2012 |
Methylation of nuclear proteins of Novikoff hepatoma.
Topics: Animals; Cell Nucleus; Histones; Kinetics; Liver; Liver Neoplasms, Experimental; Lysine; Male; Methylation; Nuclear Proteins; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1980 |
High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus).
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Crystallography, X-Ray; Deoxyadenosines; Hydrolases; Lupinus; Methylation; Models, Molecular; Molecular Conformation; Protein Binding; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine.
Topics: Azides; Click Chemistry; Coenzymes; HEK293 Cells; Humans; Methylation; Protein Methyltransferases; Proteome; Reproducibility of Results; S-Adenosylmethionine; Sequence Homology, Amino Acid | 2012 |
Structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor and implications for the mechanism of isoprenoid modification.
Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Diphosphates; Diterpenes; Methylation; Methyltransferases; Protein Conformation; S-Adenosylmethionine; Streptomyces coelicolor | 2012 |
Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Hepatitis, Alcoholic; Hepatocytes; Histones; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Lysine; Mallory Bodies; Methylation; Mice; Microscopy, Electron; Polycomb Repressive Complex 2; Proliferating Cell Nuclear Antigen; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Transcription Factors | 2012 |
The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures.
Topics: Aged; Bone Density; Female; Homocysteine; Humans; Incidence; Linear Models; Methylation; Middle Aged; Netherlands; Osteoporotic Fractures; Proportional Hazards Models; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult | 2012 |
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Crystallization; Crystallography, X-Ray; Cytidine; Dimerization; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Recombinant Proteins; RNA, Ribosomal, 16S; S-Adenosylmethionine; Scattering, Small Angle; Solutions; X-Ray Diffraction | 2012 |
Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.
Topics: Amino Acid Sequence; Animals; Arsenicals; Arsenites; Base Sequence; Cloning, Molecular; Female; Male; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Recombinant Proteins; RNA, Messenger; S-Adenosylmethionine; Sequence Alignment; Sequence Analysis, DNA; Sodium Selenite; Zebrafish | 2012 |
Identification and characterization of the Thermus thermophilus 5-methylcytidine (m5C) methyltransferase modifying 23 S ribosomal RNA (rRNA) base C1942.
Topics: Bacterial Proteins; Coenzymes; Crystallography, X-Ray; Methylation; Methyltransferases; Ribosome Subunits, Large, Bacterial; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Thermus thermophilus | 2012 |
Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.
Topics: Antibiotics, Antineoplastic; Coumarins; Glycosides; Methylation; Methyltransferases; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine; Streptomyces | 2012 |
Binding of DNA methyltransferase M.Ecl18kI [corrected] to operator-promoter region decreases its methylating activity.
Topics: Bacterial Proteins; DNA; DNA-Cytosine Methylases; Kinetics; Methylation; Operator Regions, Genetic; Promoter Regions, Genetic; S-Adenosylmethionine | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione.
Topics: Animals; Arsenicals; Arsenites; Glutathione; Humans; Methylation; Methyltransferases; Phosphines; Polymorphism, Genetic; Rats; S-Adenosylmethionine; Thioredoxin-Disulfide Reductase | 2012 |
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult | 2012 |
S-adenosylmethionine-dependent protein methylation is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes.
Topics: Adenosylhomocysteinase; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gluconeogenesis; Glucose-6-Phosphate; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Phosphoenolpyruvate Carboxykinase (GTP); Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Selenoprotein P | 2012 |
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides.
Topics: Amino Acid Sequence; Animals; Ion Channels; Marine Toxins; Metagenome; Methylation; Molecular Sequence Data; Protein Biosynthesis; Protein Processing, Post-Translational; Proteins; Ribosomes; S-Adenosylmethionine; Theonella | 2012 |
Radical SAM-dependent carbon insertion into the nitrogenase M-cluster.
Topics: Bacterial Proteins; Carbon; Catalytic Domain; Deuterium Exchange Measurement; Methylation; Methyltransferases; Nitrogenase; RNA; S-Adenosylmethionine | 2012 |
S-adenosyl-L-methionine usage during climacteric ripening of tomato in relation to ethylene and polyamine biosynthesis and transmethylation capacity.
Topics: Adenosine Kinase; Adenosylmethionine Decarboxylase; Cyclopropanes; Ethylenes; Fruit; Gene Expression Regulation, Plant; Metabolic Networks and Pathways; Methylation; Plant Growth Regulators; Plant Proteins; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Solanum lycopersicum; Up-Regulation | 2013 |
Lupus autoimmunity altered by cellular methylation metabolism.
Topics: Animals; Autoimmunity; B-Lymphocytes; Cell Proliferation; Cytokines; Female; Humans; Lupus Erythematosus, Systemic; Lymphocyte Activation; Methylation; Mice; Mice, Inbred MRL lpr; Mice, Transgenic; S-Adenosylmethionine; T-Lymphocytes; Th1 Cells; Th2 Cells | 2013 |
Methyl group balance in brain and liver: role of choline on increased S-adenosyl methionine (SAM) demand by chronic arsenic exposure.
Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Choline; Female; Immunohistochemistry; Liver; Male; Methylation; Phosphatidylcholines; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Triglycerides | 2012 |
Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation.
Topics: Amino Acid Sequence; Binding Sites; Cations, Divalent; Crystallography, X-Ray; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Polyisoprenyl Phosphates; Protein Conformation; Protein Multimerization; S-Adenosylmethionine; Sequence Alignment; Streptomyces; Substrate Specificity | 2012 |
Structural characterization of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Deoxyribonucleases, Type I Site-Specific; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Subunits; S-Adenosylmethionine; Sequence Alignment; Vibrio vulnificus | 2012 |
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1).
Topics: Bacteria; Bacterial Proteins; Crystallography, X-Ray; Methylation; Oxidoreductases; Protein Structure, Tertiary; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Sequence Homology, Amino Acid; tRNA Methyltransferases | 2012 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Culture Media; Embryonic Stem Cells; Epigenesis, Genetic; Fibroblasts; Glycine; Histones; Induced Pluripotent Stem Cells; Metabolic Networks and Pathways; Methylation; Mice; Pluripotent Stem Cells; S-Adenosylmethionine; Threonine; Transcription Factors | 2013 |
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.
Topics: Adenine; Methylation; Methyltransferases; Mutation; Nuclear Proteins; Protein O-Methyltransferase; Ribonucleoproteins, Small Nucleolar; Ribosome Subunits, Large, Eukaryotic; RNA, Ribosomal; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Sequence Deletion | 2013 |
Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems.
Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Survival; Cytochromes c; Disulfides; Glutaredoxins; Glutathione; Humans; Intracellular Space; Methanol; Methylation; Organoselenium Compounds; Oxidation-Reduction; Protein Binding; S-Adenosylmethionine; Selenium Compounds; Superoxides; Thioredoxin-Disulfide Reductase; Thioredoxins | 2012 |
Triple shifts and thioether assistance in rearrangements associated with an unusual biomethylation of the sterol side chain.
Topics: Methylation; Molecular Structure; Quantum Theory; S-Adenosylmethionine; Sterols; Sulfides | 2013 |
The mechanisms of radical SAM/cobalamin methylations: an evolving working hypothesis.
Topics: Anti-Bacterial Agents; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiostrepton; Tryptophan; Vitamin B 12 | 2013 |
Production of a novel O-methyl-isoflavone by regioselective sequential hydroxylation and O-methylation reactions in Streptomyces avermitilis host system.
Topics: Amino Acid Sequence; Bacterial Proteins; Biotechnology; Gas Chromatography-Mass Spectrometry; Hydroxylation; Isoflavones; Methionine Adenosyltransferase; Methylation; Methyltransferases; Molecular Sequence Data; Phylogeny; S-Adenosylmethionine; Sequence Alignment; Stereoisomerism; Streptomyces | 2013 |
Methylation metabolites in amniotic fluid depend on gestational age.
Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2013 |
A tandem chemoenzymatic methylation by S-adenosyl-L-methionine.
Topics: Actinomycetales; Methylation; Methyltransferases; Micromonosporaceae; Models, Molecular; S-Adenosylmethionine | 2013 |
Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine.
Topics: Amino Acid Sequence; Azides; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Mass Spectrometry; Methylation; Molecular Sequence Data; Mutation; Proteins; Proteome; S-Adenosylmethionine; Staining and Labeling | 2013 |
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
Topics: Biocatalysis; Free Radicals; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2013 |
Functional evaluation of Asp76, 84, 102 and 150 in human arsenic(III) methyltransferase (hAS3MT) interacting with S-adenosylmethionine.
Topics: Amino Acid Substitution; Arsenic; Catalytic Domain; Circular Dichroism; Humans; Hydrogen Bonding; Kinetics; Methylation; Methyltransferases; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Secondary; S-Adenosylmethionine; Spectroscopy, Fourier Transform Infrared | 2013 |
Cysteine methylation controls radical generation in the Cfr radical AdoMet rRNA methyltransferase.
Topics: Cysteine; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Free Radicals; Ligands; Methylation; Methyltransferases; Protein Binding; Recombinant Proteins; S-Adenosylmethionine | 2013 |
Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A.
Topics: Autophagy; Intracellular Signaling Peptides and Proteins; Methionine; Methylation; Protein Methyltransferases; Protein Phosphatase 2; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
Conservation of structure and mechanism by Trm5 enzymes.
Topics: Archaeal Proteins; Catalysis; Catalytic Domain; Humans; Kinetics; Methanococcus; Methylation; Models, Molecular; Protein Conformation; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2013 |
Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity.
Topics: Catalysis; HeLa Cells; Humans; Lysine; Membrane Proteins; Methylation; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2013 |
Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1.
Topics: Animals; Arginine; Biocatalysis; Methylation; Models, Molecular; Molecular Dynamics Simulation; Protein Structure, Secondary; Protein-Arginine N-Methyltransferases; Protons; Quantum Theory; Rats; S-Adenosylmethionine; Static Electricity; Thermodynamics | 2013 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
Identification of an intermediate methyl carrier in the radical S-adenosylmethionine methylthiotransferases RimO and MiaB.
Topics: Bacterial Proteins; Biocatalysis; Free Radicals; Methylation; Molecular Structure; S-Adenosylmethionine; Sulfhydryl Compounds; Thermotoga maritima | 2013 |
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.
Topics: HEK293 Cells; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Signaling Peptides and Proteins; Methylation; Neoplasm Proteins; Neoplasms; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 2013 |
KtzJ-dependent serine activation and O-methylation by KtzH for kutznerides biosynthesis.
Topics: Actinobacteria; Anti-Infective Agents; Antifungal Agents; Depsipeptides; Methylation; Methyltransferases; S-Adenosylmethionine; Serine; Substrate Specificity | 2014 |
Residues in human arsenic (+3 oxidation state) methyltransferase forming potential hydrogen bond network around S-adenosylmethionine.
Topics: Amino Acids; Arsenic; Binding Sites; Catalysis; Gene Expression; Humans; Hydrogen Bonding; Kinetics; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity | 2013 |
Metabolism of selenite to selenosugar and trimethylselenonium in vivo: tissue dependency and requirement for S-adenosylmethionine-dependent methylation.
Topics: Adenosine; Animals; Dietary Supplements; Erythrocytes; Kidney; Liver; Male; Methylation; Molecular Weight; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenious Acid; Selenium; Selenium Compounds; Selenoproteins | 2013 |
Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations.
Topics: Acyltransferases; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Escherichia coli; Fatty Acids, Monounsaturated; Methylation; Methyltransferases; Molecular Structure; Multienzyme Complexes; Multigene Family; Myxococcales; Phylogeny; Polyketide Synthases; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Analysis | 2013 |
Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues.
Topics: Amino Acid Sequence; Binding Sites; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Sequence Alignment; Substrate Specificity | 2014 |
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.
Topics: Gene Deletion; Methylation; Methyltransferases; Nuclear Proteins; RNA, Ribosomal; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Uridine | 2014 |
Methionine is a signal of amino acid sufficiency that inhibits autophagy through the methylation of PP2A.
Topics: Animals; Autophagy; Methionine; Methylation; Protein Phosphatase 2; S-Adenosylmethionine | 2014 |
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Molecular Docking Simulation; Molecular Sequence Data; Mutation; S-Adenosylmethionine; Substrate Specificity; Zinc | 2013 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
C-H methylation of heteroarenes inspired by radical SAM methyl transferase.
Topics: Hydrocarbons, Aromatic; Methylation; Organometallic Compounds; S-Adenosylmethionine; Sulfinic Acids; Transferases; Zinc | 2014 |
Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae.
Topics: Basic-Leucine Zipper Transcription Factors; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Green Fluorescent Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitination | 2014 |
Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Cognition; Cyclin E; Fibroblast Growth Factor 2; Gene Expression Regulation; Glycine N-Methyltransferase; Hippocampus; MAP Kinase Signaling System; Maze Learning; Memory Disorders; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; Rotarod Performance Test; S-Adenosylmethionine | 2014 |
Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.
Topics: Cell Adhesion; Endothelial Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Leukocytes; Methylation; Methyltransferases; Oxidative Stress; RNA, Transfer, Amino Acyl; RNA, Transfer, Ser; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium; Selenoproteins | 2014 |
Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Topics: Amino Acid Sequence; Arginine; Catalytic Domain; Crystallography, X-Ray; Guanidine; Histones; Methylation; Models, Molecular; Molecular Sequence Data; Protein Multimerization; Protein-Arginine N-Methyltransferases; Protozoan Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypanosoma brucei brucei | 2014 |
Interaction of plasma glutathione redox and folate deficiency on arsenic methylation capacity in Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Glutathione; Glutathione Disulfide; Humans; Male; Methylation; Methyltransferases; Middle Aged; Oxidation-Reduction; S-Adenosylmethionine | 2014 |
Computational analysis of methyl transfer reactions in dengue virus methyltransferase.
Topics: Dengue; Dengue Virus; Humans; Methylation; Methyltransferases; Models, Molecular; S-Adenosylmethionine; Thermodynamics | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Increased methylation demand exacerbates ethanol-induced liver injury.
Topics: Alcohol Drinking; Amidinotransferases; Animals; Chemical and Drug Induced Liver Injury; Diet; Ethanol; Fatty Liver, Alcoholic; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2014 |
Striatal adenosine A2A receptor expression is controlled by S-adenosyl-L-methionine-mediated methylation.
Topics: Animals; Corpus Striatum; Methylation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; S-Adenosylmethionine | 2014 |
Impairing methylations at ribosome RNA, a point mutation-dependent strategy for aminoglycoside resistance: the rsmG case.
Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Catalytic Domain; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Phylogeny; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Ribosomal Protein S9; Ribosomal Proteins; RNA Processing, Post-Transcriptional; RNA, Bacterial; RNA, Ribosomal, 16S; S-Adenosylmethionine; Sequence Alignment; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology, Amino Acid; Streptomycin | 2014 |
Characterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6.
Topics: Bacteria; Hydroxylation; Kinetics; Methylation; Methyltransferases; Models, Molecular; Polyketide Synthases; Protein Structure, Tertiary; Resorcinols; S-Adenosylmethionine; Streptomyces; Substrate Specificity | 2014 |
Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases.
Topics: Amino Acid Sequence; Bacteria; Bacterial Proteins; Base Sequence; Epigenesis, Genetic; Evolution, Molecular; Genome, Bacterial; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Phylogeny; RNA Processing, Post-Transcriptional; RNA, Untranslated; S-Adenosylmethionine; Sequence Alignment | 2014 |
Arsenic biotransformation by Streptomyces sp. isolated from rice rhizosphere.
Topics: Amino Acid Sequence; Arsenic; Arsenicals; Arsenites; Bacteria; Base Sequence; Biotransformation; Cacodylic Acid; Methylation; Methyltransferases; Molecular Sequence Data; Oryza; Plant Roots; Rhizosphere; RNA, Ribosomal, 16S; S-Adenosylmethionine; Soil; Soil Microbiology; Soil Pollutants; Streptomyces | 2015 |
Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs.
Topics: Adenosine; Binding Sites; Codon; Escherichia coli Proteins; HeLa Cells; Humans; Methylation; Proteins; RNA, Transfer, Ser; RNA, Transfer, Thr; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2014 |
Proteomic analysis of protein methylation in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Isotope Labeling; Methylation; Molecular Sequence Data; Protein Methyltransferases; Protein Processing, Post-Translational; Proteome; Proteomics; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tandem Mass Spectrometry | 2015 |
Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells.
Topics: Antiviral Agents; Cell Line; Cell Line, Tumor; Dexamethasone; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression; Glucocorticoids; Hep G2 Cells; Hepatitis B virus; Humans; Immunoblotting; Interferon-alpha; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Signal Transduction; STAT1 Transcription Factor | 2014 |
Identification and characterization of arsenite methyltransferase from an archaeon, Methanosarcina acetivorans C2A.
Topics: Arsenic; Biotransformation; Cloning, Molecular; Conserved Sequence; Cysteine; Escherichia coli; Genes, Archaeal; Glutathione; Inactivation, Metabolic; Methanosarcina; Methylation; Methyltransferases; S-Adenosylmethionine; Sulfhydryl Compounds; Volatilization | 2014 |
In vitro methylation assay to study protein arginine methylation.
Topics: Arginine; Carrier Proteins; DNA Helicases; Humans; Methylation; Poly-ADP-Ribose Binding Proteins; Protein-Arginine N-Methyltransferases; RNA Helicases; RNA Recognition Motif Proteins; S-Adenosylmethionine | 2014 |
Structure-guided DOT1L probe optimization by label-free ligand displacement.
Topics: Adenosine; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Neoplastic; High-Throughput Screening Assays; Histone-Lysine N-Methyltransferase; Histones; Humans; Ligands; Methylation; Methyltransferases; Models, Molecular; Phenylurea Compounds; Recombinant Fusion Proteins; S-Adenosylmethionine; Small Molecule Libraries; Structure-Activity Relationship | 2015 |
Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity.
Topics: Acyl-CoA Dehydrogenases; Amino Acid Sequence; Electron-Transferring Flavoproteins; Escherichia coli; Gene Expression; Glutaryl-CoA Dehydrogenase; HEK293 Cells; HeLa Cells; Humans; Lysine; Methylation; Methyltransferases; Mitochondria; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; S-Adenosylmethionine; Sequence Alignment | 2015 |
Mutational analysis of residues in human arsenic (III) methyltransferase (hAS3MT) belonging to 5 Å around S-adenosylmethionine (SAM).
Topics: Alanine; Amino Acid Substitution; Binding Sites; Circular Dichroism; Humans; Kinetics; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Conformation; S-Adenosylmethionine; Spectroscopy, Fourier Transform Infrared | 2014 |
Reversed phase and cation exchange liquid chromatography with spectrophotometric and elemental/molecular mass spectrometric detection for S-adenosyl methionine/S-adenosyl homocysteine ratios as methylation index in cell cultures of ovarian cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Reverse-Phase; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Female; Homocysteine; Humans; Methylation; Molecular Weight; Ovarian Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Computational Study of Symmetric Methylation on Histone Arginine Catalyzed by Protein Arginine Methyltransferase PRMT5 through QM/MM MD and Free Energy Simulations.
Topics: Arginine; Biocatalysis; Histones; Humans; Kinetics; Methylation; Molecular Dynamics Simulation; Protein-Arginine N-Methyltransferases; Protons; Quantum Theory; S-Adenosylmethionine; Substrate Specificity; Thermodynamics | 2015 |
N-mustard analogs of S-adenosyl-L-methionine as biochemical probes of protein arginine methylation.
Topics: Alkynes; Amino Acid Sequence; Arginine; Azides; Biotinylation; Chromatography, High Pressure Liquid; Click Chemistry; Humans; Methylation; Molecular Sequence Data; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization | 2015 |
Mechanistic Studies of the Radical S-Adenosyl-L-methionine Enzyme 4-Demethylwyosine Synthase Reveal the Site of Hydrogen Atom Abstraction.
Topics: Archaeal Proteins; Biocatalysis; Carbon Radioisotopes; Carboxy-Lyases; Catalytic Domain; Deuterium; Free Radicals; Guanosine; Iron-Sulfur Proteins; Methanococcus; Methylation; Models, Molecular; Pyruvic Acid; RNA, Archaeal; RNA, Transfer, Phe; S-Adenosylmethionine; Stereoisomerism | 2015 |
Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2'-O-methyltransferase.
Topics: Alkenes; Anticodon; Base Sequence; Binding Sites; Biocatalysis; Codon; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Multimerization; Pyrimidines; RNA, Transfer, Leu; S-Adenosylmethionine; Substrate Specificity | 2015 |
Guanidinoacetate is more effective than creatine at enhancing tissue creatine stores while consequently limiting methionine availability in Yucatan miniature pigs.
Topics: Animals; Body Weight; Creatine; Diet; Dietary Supplements; Glycine; Liver; Methionine; Methylation; Muscles; S-Adenosylmethionine; Swine; Swine, Miniature; Tissue Distribution | 2015 |
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Binding Sites; Biocatalysis; Crystallography, X-Ray; Escherichia coli Proteins; Guanine; Haemophilus influenzae; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; RNA, Transfer; S-Adenosylmethionine; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; tRNA Methyltransferases | 2015 |
Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Catalysis; Cephalosporins; Chromatography, Liquid; Cloning, Molecular; DNA Methylation; Drug Design; Escherichia coli; Fermentation; Methylation; Penicillins; S-Adenosylmethionine; Streptomyces; Tandem Mass Spectrometry; Thienamycins; Vitamin B 12 | 2015 |
Kinetic Analysis of tRNA Methyltransferases.
Topics: Catalysis; Escherichia coli Proteins; Humans; Kinetics; Methylation; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2015 |
Radical SAM-Mediated Methylation of Ribosomal RNA.
Topics: Adenosine; Catalysis; Escherichia coli Proteins; Methylation; Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Ribosomal; S-Adenosylmethionine; tRNA Methyltransferases | 2015 |
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Topics: Animals; Autophagy; Cell Culture Techniques; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Methionine; Methylation; Mice; Protein Phosphatase 2; S-Adenosylmethionine | 2016 |
Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.
Topics: Animals; Carbon; Chromatin; Epigenesis, Genetic; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver; Methionine; Methylation; Mice; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Regiocomplementary O-Methylation of Catechols by Using Three-Enzyme Cascades.
Topics: Animals; Archaea; Archaeal Proteins; Catechol O-Methyltransferase; Catechols; Chromatography, High Pressure Liquid; Methionine; Methionine Adenosyltransferase; Methylation; N-Glycosyl Hydrolases; Oxygen; Rats; S-Adenosylmethionine; Spectrophotometry; Stereoisomerism | 2015 |
S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation.
Topics: Cell Line; Endothelial Cells; Enhancer of Zeste Homolog 2 Protein; Humans; Inflammation; Methylation; Methyltransferases; NF-kappa B; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
X-ray structure and activities of an essential Mononegavirales L-protein domain.
Topics: Animals; Binding Sites; Chromatography, Thin Layer; Crystallization; Crystallography, X-Ray; Metapneumovirus; Methylation; Mononegavirales; Protein Structure, Tertiary; RNA; RNA Caps; RNA-Dependent RNA Polymerase; S-Adenosylmethionine; Sf9 Cells; Spodoptera; Viral Proteins | 2015 |
Identification and Analysis of the SET-Domain Family in Silkworm, Bombyx mori.
Topics: Amino Acid Sequence; Animals; Bombyx; Insect Proteins; Methylation; Methyltransferases; Molecular Sequence Data; Phylogeny; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Alignment | 2015 |
Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity.
Topics: Allosteric Regulation; Biological Assay; Conserved Sequence; Dimerization; Electrophoresis, Gel, Two-Dimensional; Fluorescence; Methylation; Models, Molecular; Molecular Dynamics Simulation; Protein Structure, Secondary; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2015 |
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Human Embryonic Stem Cells; Humans; Lysine; Mass Spectrometry; Metabolome; Metabolomics; Methylation; Mice; Niacinamide; Nicotinamide N-Methyltransferase; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Signal Transduction | 2015 |
Discovery and characterization of new O-methyltransferase from the genome of the lignin-degrading fungus Phanerochaete chrysosporium for enhanced lignin degradation.
Topics: Biodegradation, Environmental; Cloning, Molecular; Coriolaceae; DNA, Fungal; Escherichia coli; Fungal Proteins; Genes, Fungal; Lignin; Methylation; Methyltransferases; Models, Molecular; Phanerochaete; Phenols; Protein Conformation; Recombinant Fusion Proteins; S-Adenosylmethionine; Species Specificity; Substrate Specificity | 2016 |
Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Computational Biology; Enzyme Stability; Isoenzymes; Lysine; Methylation; Models, Molecular; Mutation; Peptide Elongation Factor Tu; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Unfolding; Pseudomonas aeruginosa; Recombinant Fusion Proteins; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity; Temperature | 2016 |
In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity.
Topics: Animals; In Vitro Techniques; Leishmania; Methylation; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine; Tritium | 2016 |
Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP.
Topics: Histone-Lysine N-Methyltransferase; Histones; Humans; Mass Spectrometry; Methylation; Multiprotein Complexes; Protein Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Substrate Specificity; Transcription Factors | 2016 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 2016 |
Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin.
Topics: Anti-Bacterial Agents; Binding Sites; Catalysis; Crystallography, X-Ray; Kinetics; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Riboflavin; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptomyces | 2016 |
Single-Turnover Kinetics of Methyl Transfer to tRNA by Methyltransferases.
Topics: Denaturing Gradient Gel Electrophoresis; Enzyme Assays; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; Transcription, Genetic; tRNA Methyltransferases | 2016 |
Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme.
Topics: Animals; Biofuels; Drosophila melanogaster; Drosophila Proteins; Enzyme Assays; Escherichia coli; Fatty Acids; Industrial Microbiology; Metabolic Engineering; Methylation; Methyltransferases; Reproducibility of Results; S-Adenosylmethionine | 2016 |
Neuregulin 1 Promotes Glutathione-Dependent Neuronal Cobalamin Metabolism by Stimulating Cysteine Uptake.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Androstadienes; Cell Line, Tumor; Cysteine; Excitatory Amino Acid Transporter 3; Glutathione; Humans; Low Density Lipoprotein Receptor-Related Protein-2; Methylation; Neuregulin-1; Neurons; Real-Time Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Vitamin B 12; Wortmannin | 2016 |
Deregulation of S-adenosylmethionine biosynthesis and regeneration improves methylation in the E. coli de novo vanillin biosynthesis pathway.
Topics: Benzaldehydes; Escherichia coli; Gene Expression Regulation, Bacterial; Metabolic Engineering; Metabolic Networks and Pathways; Methylation; Methyltransferases; Organisms, Genetically Modified; S-Adenosylmethionine | 2016 |
Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Topics: Adenosine; Alanine; Amino Acid Substitution; Anticodon; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli Proteins; Methylation; Methyltransferases; Nucleic Acid Conformation; Protein Structure, Tertiary; RNA, Bacterial; RNA, Transfer, Glu; S-Adenosylmethionine | 2016 |
Nucleosome Binding Alters the Substrate Bonding Environment of Histone H3 Lysine 36 Methyltransferase NSD2.
Topics: Binding Sites; Computational Biology; Histone-Lysine N-Methyltransferase; Humans; Methylation; Models, Molecular; Models, Theoretical; Nucleosomes; Protein Binding; Repressor Proteins; S-Adenosylmethionine | 2016 |
aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism.
Topics: Archaeal Proteins; Crystallography, X-Ray; Gene Deletion; Gene Expression Regulation, Archaeal; Lysine; Mass Spectrometry; Methylation; Models, Molecular; Protein Methyltransferases; Protein Structure, Secondary; Proteomics; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfolobus | 2016 |
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Topics: Adenosine; Allosteric Regulation; Binding Sites; Catalytic Domain; HEK293 Cells; Humans; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Conformation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 2016 |
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Benzimidazoles; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Methylation; Methyltransferases; Models, Molecular; Molecular Structure; Mutation; Mycobacterium tuberculosis; Protein Domains; Repressor Proteins; S-Adenosylmethionine | 2016 |
SAM - a helping hand in many places.
Topics: Enzymes; Free Radicals; Histones; Methylation; Mycobacterium tuberculosis; S-Adenosylmethionine | 2016 |
Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin.
Topics: Anti-Bacterial Agents; Hexoses; Leucomycins; Methylation; Methyltransferases; Molecular Structure; Mutation; S-Adenosylmethionine; Streptomyces; Tylosin | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
S-Adenosylmethionine Synthetase 3 Is Important for Pollen Tube Growth.
Topics: Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Histones; Metabolomics; Methionine; Methionine Adenosyltransferase; Methylation; Microscopy, Fluorescence; Mutation; Plants, Genetically Modified; Pollen; Pollen Tube; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Seeds | 2016 |
Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Topics: Amino Acid Motifs; Binding Sites; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Gene Expression; Holoenzymes; Methylation; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Transfer, Met; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; tRNA Methyltransferases | 2016 |
Differential neurogenic effects of casein-derived opioid peptides on neuronal stem cells: implications for redox-based epigenetic changes.
Topics: Analgesics, Opioid; Animals; Apoptosis; Astrocytes; Caseins; Cattle; Cell Proliferation; Cells, Cultured; DNA Methylation; Endorphins; Epigenesis, Genetic; Glutathione; Humans; Methylation; Morphine; Neural Stem Cells; Neurogenesis; Opioid Peptides; Oxidation-Reduction; Peptide Fragments; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI.
Topics: Amino Acid Sequence; Catalytic Domain; Escherichia coli Proteins; Methylation; Methyltransferases; Molecular Docking Simulation; Protein Multimerization; Protein Structure, Quaternary; RNA, Ribosomal, 16S; S-Adenosylmethionine | 2016 |
Evolutionary Adaptation of the Essential tRNA Methyltransferase TrmD to the Signaling Molecule 3',5'-cAMP in Bacteria.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Escherichia coli; Evolution, Molecular; Humans; Kinetics; Methylation; Models, Molecular; Phylogeny; Protein Conformation; S-Adenosylmethionine; Sequence Homology, Amino Acid; Staphylococcus aureus; Substrate Specificity; tRNA Methyltransferases | 2017 |
Spontaneous Emergence of S-Adenosylmethionine and the Evolution of Methylation.
Topics: Adenosine; Adenosine Triphosphate; Methylation; Methyltransferases; Nucleic Acid Conformation; S-Adenosylmethionine | 2017 |
Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN.
Topics: Methylation; Methyltransferases; Point Mutation; Protein Binding; RNA, Transfer; S-Adenosylmethionine; Transcription, Genetic | 2016 |
The B
Topics: Biocatalysis; Free Radicals; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Molecular Conformation; Proteins; S-Adenosylmethionine; Vitamin B 12 | 2016 |
Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.
Topics: Binding, Competitive; Catalysis; Cell Cycle; Computer Simulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Isotopes; Kinetics; Lysine; Methylation; Models, Molecular; Models, Theoretical; Neoplasm Metastasis; Peptides; Protein Structure, Secondary; S-Adenosylmethionine; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2016 |
Arsenic methylation by an arsenite S-adenosylmethionine methyltransferase from Spirulina platensis.
Topics: Arsenic; Hazardous Substances; Methylation; Methyltransferases; S-Adenosylmethionine; Spirulina | 2016 |
The Catalytic Mechanism of the Class C Radical S-Adenosylmethionine Methyltransferase NosN.
Topics: Anti-Bacterial Agents; Catalysis; Free Radicals; Methylation; Methyltransferases; Molecular Structure; S-Adenosylmethionine; Thiazoles | 2017 |
Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity.
Topics: Apoenzymes; Biocatalysis; Calibration; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Limit of Detection; Methylation; Models, Molecular; Nicotinamide N-Methyltransferase; Protein Conformation; Protein Refolding; Quinolinium Compounds; Recombinant Proteins; Reproducibility of Results; S-Adenosylmethionine; Spectrometry, Fluorescence | 2017 |
Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus.
Topics: Arsenic; Arsenicals; Arsenites; Aspergillus fumigatus; Conserved Sequence; Cysteine; Escherichia coli; Fungal Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 2017 |
RNase E and RNase J are needed for S-adenosylmethionine homeostasis in Sinorhizobium meliloti.
Topics: ATP-Binding Cassette Transporters; Bacterial Proteins; Endoribonucleases; Flagellin; Gene Expression Regulation, Bacterial; Methylation; Methyltransferases; Quorum Sensing; RNA, Messenger; S-Adenosylmethionine; Sinorhizobium meliloti | 2017 |
Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin.
Topics: Binding Sites; Catalytic Domain; Chromatography, High Pressure Liquid; Citrinin; Cloning, Molecular; Crystallography, X-Ray; Fungi; Methylation; Molecular Docking Simulation; Monascus; Phylogeny; Polyketide Synthases; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2017 |
Novel immunoassays to detect methionine adenosyltransferase activity and quantify S-adenosylmethionine.
Topics: Active Transport, Cell Nucleus; Animals; Antibody Specificity; Cell Line; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cytoplasm; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hep G2 Cells; Hepatocytes; Humans; Methionine Adenosyltransferase; Methylation; Mice; Microscopy, Fluorescence; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
A Metabolic Function for Phospholipid and Histone Methylation.
Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic | 2017 |
A Tandem Enzymatic sp
Topics: Alkylation; Aquatic Organisms; Bacteria; Biocatalysis; Heterocyclic Compounds, Fused-Ring; Hydrocarbons, Aromatic; Isotope Labeling; Methylation; Methyltransferases; S-Adenosylmethionine | 2017 |
Nicotinamide N-Methyltransferase Suppression Participates in Nickel-Induced Histone H3 Lysine9 Dimethylation in BEAS-2B Cells.
Topics: Cell Line; Histones; Humans; Intercellular Signaling Peptides and Proteins; MAP Kinase Kinase 3; Methylation; Nickel; Nicotinamide N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine.
Topics: Adenosine; Binding Sites; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Pseudouridine; RNA, Ribosomal, 23S; S-Adenosylmethionine; Substrate Specificity | 2017 |
Metabolic perturbation of epigenome by inhibiting S-adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells.
Topics: Adenosine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Proliferation; Cellular Senescence; Chromatin; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Epigenomics; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 2017 |
Methylated Phenylarsenical Metabolites Discovered in Chicken Liver.
Topics: Animal Feed; Animals; Arsenicals; Chickens; Food Additives; Inhibitory Concentration 50; Liver; Methylation; Methyltransferases; Oxidation-Reduction; S-Adenosylmethionine | 2017 |
The U6 snRNA m
Topics: Animals; Base Sequence; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Introns; Inverted Repeat Sequences; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA Splicing; S-Adenosylmethionine; Schizosaccharomyces | 2017 |
Structural and biochemical insights into the 2'-O-methylation of pyrimidines 34 in tRNA.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Deoxyadenosines; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Pyrimidines; RNA, Transfer, Leu; S-Adenosylmethionine; Substrate Specificity; Thermus thermophilus; Thionucleosides; tRNA Methyltransferases | 2017 |
Spermidine promotes
Topics: Adenosylmethionine Decarboxylase; Bacillus subtilis; Bacterial Proteins; Biofilms; Cadaverine; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Methionine; Methylation; Nitrogen Cycle; Operon; Polysaccharides, Bacterial; Purines; S-Adenosylmethionine; Single-Cell Analysis; Spermidine; Transcription Factors | 2017 |
Polycomb repressive complex 2 in an autoinhibited state.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Apoenzymes; Chaetomium; Coenzymes; Conserved Sequence; Enhancer of Zeste Homolog 2 Protein; Fungal Proteins; Histones; Lysine; Methylation; Models, Molecular; Mutation; Peptide Fragments; Polycomb Repressive Complex 2; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Recombinant Fusion Proteins; S-Adenosylmethionine; Xenopus laevis; Xenopus Proteins | 2017 |
Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.
Topics: Bacterial Proteins; Binding Sites; Burkholderia; Catalytic Domain; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Methylation; Methyltransferases; Models, Molecular; Multigene Family; Oxidation-Reduction; Phylogeny; Protein Conformation; Pyrimidinones; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Stereoisomerism; Triazines | 2017 |
Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis.
Topics: Biosynthetic Pathways; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Streptomyces; Substrate Specificity; Vitamin B 12 | 2017 |
Automated One-pot Radiosynthesis of [11C]S-adenosyl Methionine.
Topics: Automation; Carbon Radioisotopes; Isotope Labeling; Methylation; Radiochemistry; Radiopharmaceuticals; S-Adenosylmethionine | 2017 |
Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical
Topics: Bacterial Proteins; Biocatalysis; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Kinetics; Methylation; Methyltransferases; Molecular Structure; Recombinant Fusion Proteins; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry; Staphylococcus; Substrate Specificity; Thiostrepton; Tryptophan; Vitamin B 12 | 2017 |
TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.
Topics: Bacterial Proteins; Biocatalysis; Coenzymes; Cysteine; Escherichia coli; Iron-Sulfur Proteins; Methylation; Methyltransferases; Protein Binding; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; Tryptophan; Vitamin B 12 | 2017 |
Mechanistic features of the atypical tRNA m1G9 SPOUT methyltransferase, Trm10.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Biocatalysis; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Methylation; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Recombinant Proteins; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; tRNA Methyltransferases | 2017 |
Computational characterization of substrate and product specificities, and functionality of S-adenosylmethionine binding pocket in histone lysine methyltransferases from Arabidopsis, rice and maize.
Topics: Arabidopsis; Binding Sites; Catalysis; Databases, Protein; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Models, Chemical; Molecular Structure; Oryza; Plant Proteins; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Sequence Analysis, Protein; Substrate Specificity; Zea mays | 2018 |
NosN, a Radical S-Adenosylmethionine Methylase, Catalyzes Both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide.
Topics: Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles | 2017 |
Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.
Topics: Biosynthetic Pathways; Catalytic Domain; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2017 |
Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.
Topics: Anti-Bacterial Agents; Deoxyadenosines; Hydrogen; Methylation; Methyltransferases; Peptides, Cyclic; Protons; S-Adenosylhomocysteine; S-Adenosylmethionine; Solvents; Thiazoles | 2017 |
S-Adenosylmethionine Synthesis Is Regulated by Selective N
Topics: 3' Untranslated Regions; Animals; HEK293 Cells; HeLa Cells; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; Mice; Nerve Tissue Proteins; RNA Processing, Post-Transcriptional; RNA Splicing Factors; RNA Stability; RNA, Messenger; S-Adenosylmethionine | 2017 |
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming | 2018 |
A (Re)Discovery of the Fom3 Substrate.
Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Escherichia coli; Fosfomycin; Genes, Bacterial; Methylation; Methyltransferases; Phosphoenolpyruvate; S-Adenosylmethionine; Streptomyces; Substrate Specificity | 2018 |
Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium longum; Biomarkers; Depression; Dopamine; Dopamine Antagonists; Freeze Drying; Hippocampus; Homocysteine; Lactobacillus helveticus; Liver; Male; Methylation; Neurons; Norepinephrine; Prefrontal Cortex; Probiotics; Random Allocation; Rats, Mutant Strains; S-Adenosylmethionine | 2018 |
miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes.
Topics: Adenosine; Cysteine; Escherichia coli; Escherichia coli Proteins; Immunoprecipitation; Methylation; Methyltransferases; Mutation; RNA; S-Adenosylmethionine; Sequence Analysis, RNA; Substrate Specificity | 2018 |
Investigation of Solvent Hydron Exchange in the Reaction Catalyzed by the Antibiotic Resistance Protein Cfr.
Topics: Biocatalysis; Cysteine; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Methylation; Methyltransferases; RNA, Ribosomal, 23S; S-Adenosylmethionine; Water | 2018 |
The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.
Topics: Arsenic; Binding Sites; Crystallography, X-Ray; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Rhodophyta; S-Adenosylmethionine | 2018 |
C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-adenosyl-l-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Liquid; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Stereospecific Radical-Mediated B
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Free Radicals; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Topics: Animals; Biological Transport; Brain; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cell Nucleus; ELAV-Like Protein 1; Endoplasmic Reticulum Stress; Exportin 1 Protein; Humans; Karyopherins; Metabolic Diseases; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; Receptors, Cytoplasmic and Nuclear; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Sirtuin 1; Vitamin B 12 | 2018 |
Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase.
Topics: Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B
Topics: Anisoles; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Enzyme Assays; Esters; Free Radicals; Methylation; Methyltransferases; Myxococcales; Nitro Compounds; Recombinant Proteins; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide.
Topics: Bacterial Proteins; Biosynthetic Pathways; Enzyme Assays; Methylation; Methyltransferases; Peptides; Recombinant Proteins; S-Adenosylmethionine; Streptomyces; Thiazoles | 2018 |
Sodorifen Biosynthesis in the Rhizobacterium Serratia plymuthica Involves Methylation and Cyclization of MEP-Derived Farnesyl Pyrophosphate by a SAM-Dependent C-Methyltransferase.
Topics: Bridged Bicyclo Compounds; Cyclization; Erythritol; Methylation; Methyltransferases; Molecular Structure; Octanes; Polyisoprenyl Phosphates; S-Adenosylmethionine; Serratia; Sesquiterpenes; Sugar Phosphates | 2018 |
Kinetic Mechanism of Nicotinamide N-Methyltransferase.
Topics: Humans; Kinetics; Methylation; NAD; Niacinamide; Nicotinamide N-Methyltransferase; S-Adenosylmethionine | 2018 |
A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds.
Topics: Amides; Catalysis; Crystallography, X-Ray; Electrons; Methylation; Methyltransferases; Nitrogen; Peptide Fragments; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Catalytic Reaction Mechanism in Native and Mutant Catechol- O-methyltransferase from the Adaptive String Method and Mean Reaction Force Analysis.
Topics: Catalysis; Catalytic Domain; Catechol O-Methyltransferase; Dopamine; Humans; Methylation; Mutation; S-Adenosylmethionine; Thermodynamics; Water | 2018 |
Oligomerization and Auto-methylation of the Human Lysine Methyltransferase SETD6.
Topics: Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Lysine; Methylation; Models, Molecular; Molecular Weight; Oxidative Stress; Point Mutation; Protein Conformation; Protein Methyltransferases; Protein Multimerization; S-Adenosylmethionine | 2018 |
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Topics: 3' Untranslated Regions; Adenosine; Binding Sites; HEK293 Cells; Homeostasis; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2018 |
Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis.
Topics: Agaricales; Amino Acid Sequence; Catalytic Domain; Fungal Proteins; Methylation; Methyltransferases; Models, Chemical; Mutation; Peptides; Protein Binding; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 2018 |
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission | 2019 |
Rossmann-Fold Methyltransferases: Taking a "β-Turn" around Their Cofactor, S-Adenosylmethionine.
Topics: Alanine; Binding Sites; Coenzymes; Computer Simulation; Flavin-Adenine Dinucleotide; Glycine; Methylation; Methyltransferases; Mutagenesis; NAD; Protein Conformation; Protein Folding; S-Adenosylmethionine | 2019 |
A Family Divided: Distinct Structural and Mechanistic Features of the SpoU-TrmD (SPOUT) Methyltransferase Superfamily.
Topics: Catalytic Domain; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Substrate Specificity; tRNA Methyltransferases | 2019 |
Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis.
Topics: Bacterial Proteins; Catalysis; Catechol O-Methyltransferase; Escherichia coli; Kinetics; Methanocaldococcus; Methionine Adenosyltransferase; Methylation; Methyltransferases; Peptide Synthases; Phenols; Protein Domains; Pseudomonas aeruginosa; S-Adenosylmethionine; Thiazoles | 2019 |
Expression and purification of an ArsM-elastin-like polypeptide fusion and its enzymatic properties.
Topics: Arsenic; Biodegradation, Environmental; Elastin; Escherichia coli; Genetic Engineering; Methylation; Methyltransferases; Peptides; Recombinant Fusion Proteins; S-Adenosylmethionine; Temperature | 2019 |
Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation.
Topics: Carbon; Endosomes; Glycogen Synthase Kinase 3 beta; HEK293 Cells; HeLa Cells; Humans; Lysosomes; Methionine; Methotrexate; Methylation; Niacinamide; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Wnt Signaling Pathway | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Demethylation of the Protein Phosphatase PP2A Promotes Demethylation of Histones to Enable Their Function as a Methyl Group Sink.
Topics: Chromatin; Dealkylation; DNA Methylation; Gene Expression Regulation, Fungal; Histone Demethylases; Histones; Methylation; Mutation; Protein Binding; Protein Phosphatase 2; Protein Processing, Post-Translational; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Depletion of S-adenosylmethionine impacts on ribosome biogenesis through hypomodification of a single rRNA methylation.
Topics: Cell Cycle Proteins; Escherichia coli; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Methylation; Methyltransferases; Organelle Biogenesis; Ribosomes; RNA, Ribosomal; RNA, Ribosomal, 23S; RNA, Transfer; S-Adenosylmethionine | 2019 |
Coupling S-adenosylmethionine-dependent methylation to growth: Design and uses.
Topics: Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Methylation; Methyltransferases; Nitriles; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tolcapone | 2019 |
Metabolic footprint and intestinal microbial changes in response to dietary proteins in a pig model.
Topics: Acetylation; Amino Acids; Animals; Blood Glucose; Body Weight; Caseins; Dietary Proteins; Feces; Female; Gastrointestinal Microbiome; Histones; Lipids; Liver; Methylation; Red Meat; S-Adenosylhomocysteine; S-Adenosylmethionine; Seed Storage Proteins; Swine | 2019 |
Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Topics: Anticodon; Bacillus subtilis; Catalytic Domain; Crystallography, X-Ray; Methylation; Protein Conformation; RNA Recognition Motif Proteins; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2019 |
Substrate-Differentiated Transition States of SET7/9-Catalyzed Lysine Methylation.
Topics: Catalysis; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 2019 |
The interactome of a family of potential methyltransferases in HeLa cells.
Topics: Amino Acid Sequence; Binding Sites; HeLa Cells; Humans; Methylation; Methyltransferases; Multigene Family; Protein Binding; S-Adenosylmethionine; Substrate Specificity | 2019 |
Methanogenesis marker protein 10 (Mmp10) from
Topics: Archaeal Proteins; Biocatalysis; Chromatography, High Pressure Liquid; Kinetics; Matrix Metalloproteinase 10; Methanosarcina; Methylation; Peptides; Recombinant Proteins; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Vitamin B 12 | 2019 |
Enzymatic Route toward 6-Methylated Baeocystin and Psilocybin.
Topics: Alkaloids; Bacterial Proteins; Fungal Proteins; Indoles; Methylation; Methyltransferases; Molecular Docking Simulation; Molecular Structure; Organophosphates; Protein Binding; Psilocybe; Psilocybin; S-Adenosylmethionine; Salmonella enterica; Tryptophan Synthase | 2019 |
Arsenic inhibited cholesterol efflux of THP-1 macrophages via ROS-mediated ABCA1 hypermethylation.
Topics: Acetylcysteine; Antioxidants; Arsenic; ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; Macrophages; Methylation; Oxidative Stress; Reactive Oxygen Species; S-Adenosylmethionine | 2019 |
Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical
Topics: Amino Acid Sequence; Clostridioides difficile; Iron; Methylation; Phylogeny; Protein Binding; RNA; S-Adenosylmethionine | 2019 |
Somatic Cancer Mutations in the SUV420H1 Protein Lysine Methyltransferase Modulate Its Catalytic Activity.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; DNA Repair; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neoplasms; Nucleosomes; S-Adenosylmethionine | 2019 |
Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs.
Topics: 5-Methylcytosine; Animals; CRISPR-Cas Systems; Fibroblasts; Gene Editing; Gene Knockout Techniques; HEK293 Cells; HeLa Cells; Humans; Methylation; Methyltransferases; Mice; Mice, Knockout; Mitochondria; Nucleic Acid Conformation; Oxidative Phosphorylation; Primary Cell Culture; Protein Transport; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Mitochondrial; RNA, Transfer; S-Adenosylmethionine | 2019 |
Nutrigenomics and RNA methylation: Role of micronutrients.
Topics: Animals; Epigenesis, Genetic; Humans; Methylation; Micronutrients; Nutrigenomics; RNA, Transfer; S-Adenosylmethionine | 2019 |
Understanding the role of electron donors in the reaction catalyzed by Tsrm, a cobalamin-dependent radical S-adenosylmethionine methylase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Dithiothreitol; Escherichia coli; Hydroxocobalamin; Iron-Sulfur Proteins; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2019 |
Antibody-Free Assay for RNA Methyltransferase Activity Analysis.
Topics: Enzyme Assays; Humans; Methylation; Methyltransferases; RNA; S-Adenosylmethionine | 2019 |
Unraveling the role of quorum sensing-dependent metabolic homeostasis of the activated methyl cycle in a cooperative population of Burkholderia glumae.
Topics: Adenosylhomocysteinase; Bacterial Proteins; Burkholderia; Homeostasis; Ligases; Methylation; Methyltransferases; Mutation; Quorum Sensing; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Surprise! A hidden B
Topics: Biocatalysis; Matrix Metalloproteinase 10; Methylation; Oxidoreductases; Peptides; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2019 |
The Inhibitory Effect of GlmU Acetyltransferase Inhibitor TPSA on
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Binding Sites; Gene Expression; Kinetics; Methylation; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Multienzyme Complexes; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Proteome; Pyrimidines; RAW 264.7 Cells; S-Adenosylmethionine; Thiophenes; Transcriptome | 2019 |
One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages.
Topics: Adenosine Triphosphate; Adult; Animals; Female; Histones; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages, Peritoneal; Male; Methylation; Mice; S-Adenosylmethionine | 2019 |
Peptidic transition state analogues as PRMT inhibitors.
Topics: Arginine; Catalytic Domain; Enzyme Inhibitors; Histones; Inhibitory Concentration 50; Methylation; Peptides; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 2020 |
Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
Topics: Catalytic Domain; Hydrogen Bonding; Methylation; Models, Molecular; Mutant Proteins; Protein Binding; Protein Subunits; Pyrimidines; Recombinant Proteins; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; tRNA Methyltransferases; Vesicular Transport Proteins | 2019 |
The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1.
Topics: Arginine; Calorimetry, Differential Scanning; Catalysis; Coenzymes; Dimerization; Enzyme Assays; Fluorescent Dyes; Fluorometry; Gene Expression; Kinetics; Methylation; Protein Conformation, alpha-Helical; Protein-Arginine N-Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Temperature | 2020 |
Characterization of METTL16 as a cytoplasmic RNA binding protein.
Topics: Adenosine; Cytoplasm; HEK293 Cells; HeLa Cells; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; Nuclear Proteins; RNA Splicing; RNA Stability; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2020 |
Biological and chemical approaches to understanding protein arginine methylation.
Topics: Animals; Arginine; Enzymes; Epigenomics; Kinetics; Mass Spectrometry; Methylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; S-Adenosylmethionine; Yeasts | 2020 |
The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats.
Topics: Animals; Homocysteine; Humans; Hypothyroidism; Liver; Methylation; Rats; S-Adenosylmethionine; Vitamin B Complex | 2020 |
Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Exoribonucleases; Gene Expression; Guanine; Immunity, Innate; Interferon Lambda; Interferon Type I; Interferons; Methylation; Mutation; Porcine epidemic diarrhea virus; RNA Caps; RNA, Viral; S-Adenosylmethionine; Swine; Vero Cells; Viral Nonstructural Proteins; Virus Replication | 2020 |
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
Topics: Adenine; Betacoronavirus; Coronavirus Infections; COVID-19; Exoribonucleases; Humans; Methylation; Methyltransferases; Molecular Docking Simulation; Nucleosides; Pandemics; Pneumonia, Viral; RNA Caps; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2020 |
Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups.
Topics: Adenosine; Humans; Methylation; Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Adenosylmethionine; Triazoles | 2020 |
Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism.
Topics: Adenosine Triphosphate; Allosteric Regulation; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2020 |
High-resolution structures of the SARS-CoV-2 2'-
Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins | 2020 |
Site-specific RNA methylation by a methyltransferase ribozyme.
Topics: Adenosine; Base Sequence; Biocatalysis; Guanine; Methylation; Methyltransferases; Plasmids; RNA, Catalytic; RNA, Transfer; S-Adenosylmethionine | 2020 |
Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program.
Topics: Anabolic Agents; Basic-Leucine Zipper Transcription Factors; Methylation; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2020 |
A Tug-of-War Over Methionine.
Topics: Histones; Methionine; Methylation; Neoplasms; S-Adenosylmethionine; T-Lymphocytes | 2020 |
Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Topics: Arginine; Catalysis; Coenzymes; Iron-Sulfur Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomycetaceae; Thiostrepton; Tryptophan; Vitamin B 12; X-Ray Diffraction | 2021 |
Chemo-Enzymatic Modification of the 5' Cap Maintains Translation and Increases Immunogenic Properties of mRNA.
Topics: Chromatography, High Pressure Liquid; COVID-19; Genes, Reporter; HEK293 Cells; Humans; Mass Spectrometry; Methylation; Methyltransferases; Protein Biosynthesis; Protein Domains; RNA Caps; RNA, Messenger; S-Adenosylmethionine; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2021 |
mTORC1 stimulates cell growth through SAM synthesis and m
Topics: Adenosine; Animals; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Proliferation; Female; HEK293 Cells; HeLa Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Methionine Adenosyltransferase; Methylation; Mice, Nude; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; RNA Splicing Factors; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic | 2021 |
Taurine Antagonizes Macrophages M1 Polarization by Mitophagy-Glycolysis Switch Blockage
Topics: Gene Expression; Glycolysis; Humans; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Potential, Mitochondrial; Membrane Transport Proteins; Methylation; Mitophagy; Protein Kinases; Protein Phosphatase 2; S-Adenosylmethionine; Taurine; THP-1 Cells; Voltage-Dependent Anion Channel 1 | 2021 |
Splice site m
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Conserved Sequence; Diet; HeLa Cells; Humans; Introns; Methionine Adenosyltransferase; Methylation; Methyltransferases; Mice; Mutation; Nucleic Acid Conformation; Protein Binding; RNA Precursors; RNA Splice Sites; RNA Splicing; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine; Splicing Factor U2AF; Transcriptome | 2021 |
Overall Retention of Methyl Stereochemistry during B
Topics: Bacterial Proteins; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2021 |
Regulation of arsenic methylation: identification of the transcriptional region of the human AS3MT gene.
Topics: Arsenic; Endothelial Cells; Humans; Leukocytes, Mononuclear; Methylation; Methyltransferases; S-Adenosylmethionine; Transcription Factors | 2022 |
2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
Topics: Crystallography; Methylation; Methyltransferases; Multiprotein Complexes; RNA Cap Analogs; RNA Caps; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Synchrotrons; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2021 |
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2'-O methylation of its first nucleotide.
Topics: Amino Acid Sequence; Binding Sites; Biocatalysis; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression Regulation, Viral; Humans; Magnesium; Methylation; Methyltransferases; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; RNA Caps; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2021 |
Mn
Topics: Amino Acid Sequence; Catalytic Domain; COVID-19; Crystallography, X-Ray; Humans; Manganese; Methylation; Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Recombinant Proteins; RNA Caps; RNA Stability; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Signal Transduction; Substrate Specificity; Viral Nonstructural Proteins | 2021 |
A natural riboswitch scaffold with self-methylation activity.
Topics: Aptamers, Nucleotide; Base Sequence; Kinetics; Methylation; Molecular Structure; Nucleic Acid Conformation; Nucleoside Q; Riboswitch; RNA; S-Adenosylmethionine | 2021 |
Vitamin B
Topics: Adenosine; Animals; Fibroblasts; Gene Expression Regulation; Methylation; Mice, Knockout; Protein Kinase C-alpha; Receptors, Cell Surface; Recombinant Fusion Proteins; RNA, Messenger; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 Deficiency | 2021 |
Profiling and Validation of Live-Cell Protein Methylation with Engineered Enzymes and Methionine Analogues.
Topics: Humans; Methionine; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Proteome; Repressor Proteins; S-Adenosylmethionine | 2021 |
Biocatalytic C3-Indole Methylation-A Useful Tool for the Natural-Product-Inspired Stereoselective Synthesis of Pyrroloindoles.
Topics: Biocatalysis; Indoles; Kinetics; Methylation; Methyltransferases; Pyrroles; S-Adenosylmethionine; Stereoisomerism; Streptomyces | 2021 |
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Hydroxyquinolines; Methylation; Methyltransferases; Models, Chemical; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Conformation; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity | 2021 |
Fluorinated S-Adenosylmethionine as a Reagent for Enzyme-Catalyzed Fluoromethylation.
Topics: Bacteria; Bacterial Proteins; Halogenation; Hydrocarbons, Fluorinated; Indicators and Reagents; Methylation; Methyltransferases; S-Adenosylmethionine | 2021 |
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1.
Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element | 2021 |
Flagellin lysine methyltransferase FliB catalyzes a [4Fe-4S] mediated methyl transfer reaction.
Topics: Bacterial Proteins; Flagellin; Iron-Sulfur Proteins; Lysine; Methylation; Methyltransferases; S-Adenosylmethionine; Salmonella typhi | 2021 |
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease.
Topics: Animals; Methylation; Mice; Mitochondria; Mitochondrial Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
Crystallographic snapshots of a B
Topics: Archaeal Proteins; Electron Spin Resonance Spectroscopy; Methanosarcina; Methylation; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Structure of a B
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Biocatalysis; Carbapenems; Coenzymes; Crystallography, X-Ray; Kinetics; Methylation; Methyltransferases; Models, Molecular; Protein Binding; Protein Domains; S-Adenosylmethionine; Streptomyces; Thienamycins; Vitamin B 12 | 2022 |
Glycine increased ferroptosis via SAM-mediated GPX4 promoter methylation in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Ferroptosis; Fibroblasts; Glycine; Methylation; Mice; S-Adenosylmethionine; Synovial Membrane; Synoviocytes | 2022 |
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine | 2022 |
Exploring the Biosynthetic Potential of TsrM, a B
Topics: Methylation; Methyltransferases; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2022 |
The Atypical Cobalamin-Dependent
Topics: Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Methyl Metabolism and the Clock: An Ancient Story With New Perspectives.
Topics: Animals; Circadian Rhythm; Folic Acid; Humans; Mammals; Methionine; Methylation; S-Adenosylmethionine | 2022 |
Excess S-adenosylmethionine inhibits methylation via catabolism to adenine.
Topics: Adenine; Dietary Supplements; Liver; Methylation; S-Adenosylmethionine | 2022 |
Reciprocal regulation of phosphatidylcholine synthesis and H3K36 methylation programs metabolic adaptation.
Topics: Histones; Methylation; Phosphatidylcholines; Phospholipids; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2022 |
Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent
Topics: Catalytic Domain; Methylation; Methyltransferases; Polyketide Synthases; Protein Domains; S-Adenosylmethionine | 2022 |
mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine.
Topics: Animals; Humans; Mammals; Mechanistic Target of Rapamycin Complex 1; Methionine; Methionine Adenosyltransferase; Methylation; RNA, Messenger; S-Adenosylmethionine | 2022 |
A Cobalamin-Dependent Radical SAM Enzyme Catalyzes the Unique C
Topics: Glutamine; Methane; Methylation; Methyltransferases; Oxidoreductases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Computational study revealed a "pull-push" radical transfer mechanism of Mmp10-catalyzed C
Topics: Arginine; Catalysis; Methylation; Protein Processing, Post-Translational; S-Adenosylmethionine | 2022 |
Detection and Quantification of Histone Methyltransferase Activity In Vitro.
Topics: Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Methylation; Protein Processing, Post-Translational; S-Adenosylmethionine | 2022 |
A High-Throughput Continuous Spectroscopic Assay to Measure the Activity of Natural Product Methyltransferases.
Topics: Biological Products; High-Throughput Screening Assays; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
Synthetic Reagents for Enzyme-Catalyzed Methylation.
Topics: Biocatalysis; Indicators and Reagents; Methylation; Methyltransferases; Pharmaceutical Preparations; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfates; Toluene | 2022 |
S-Adenosyl-L-Methionine and Cu(II) Impact Green Plant Regeneration Efficiency.
Topics: Amplified Fragment Length Polymorphism Analysis; Methionine; Methylation; S-Adenosylmethionine; Triticale | 2022 |
Selective Methylation by an ArsM
Topics: Anti-Bacterial Agents; Arsenic; Arsenicals; Arsenites; Burkholderia gladioli; Escherichia coli; Methylation; Methyltransferases; S-Adenosylmethionine | 2022 |
An RNA link for METTL16 and DNA repair in PDAC.
Topics: DNA Repair; Methylation; RNA; S-Adenosylmethionine | 2022 |
Topics: Bacterial Proteins; Ethanol; Glucose; Methylation; Methyltransferases; Mycobacterium tuberculosis; Oxidation-Reduction; S-Adenosylmethionine | 2022 |
Mechanism of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions.
Topics: Aldehyde Dehydrogenase 1 Family; Folic Acid; Glycine; Humans; Metabolomics; Methylation; Neoplasms; Retinal Dehydrogenase; S-Adenosylmethionine | 2022 |
Elucidating the Kinetic Mechanism of Human METTL16.
Topics: Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; Nucleic Acid Conformation; RNA Splicing; RNA, Long Noncoding; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2023 |
Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Topics: Biocatalysis; Catalytic Domain; Cryoelectron Microscopy; Crystallography, X-Ray; GTP-Binding Proteins; Humans; Methylation; Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 2023 |
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors.
Topics: Antiviral Agents; Methylation; Methyltransferases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2023 |
Changing Fates of the Substrate Radicals Generated in the Active Sites of the B
Topics: Catalysis; Catalytic Domain; Free Radicals; Methylation; Methyltransferases; S-Adenosylmethionine | 2023 |
Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes.
Topics: Alkylation; Biocatalysis; Biomimetics; Methylation; Methyltransferases; S-Adenosylmethionine | 2023 |
Comparative
Topics: Alkylation; Biocatalysis; Methionine Adenosyltransferase; Methylation; Methyltransferases; S-Adenosylmethionine | 2023 |
The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation.
Topics: Crystallography, X-Ray; Humans; Lysine; Methylation; Methyltransferases; Models, Molecular; Peptide Elongation Factor 2; Point Mutation; Protein Domains; Protein Structure, Tertiary; S-Adenosylmethionine; Substrate Specificity | 2023 |
Methyltransferase-like (METTL) homologues participate in
Topics: Antiviral Agents; Humans; Methylation; Methyltransferases; Nicotiana; S-Adenosylmethionine | 2023 |
Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition-Metal-Catalyzed Reactions.
Topics: Catalysis; Methylation; Methyltransferases; RNA; S-Adenosylmethionine | 2023 |
Optimizing purification and activity assays of N-terminal methyltransferase complexes.
Topics: Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity | 2023 |
Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of
Topics: 3' Untranslated Regions; Adenosine; Chromosomal Proteins, Non-Histone; Gene Expression Regulation; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA, Messenger; S-Adenosylmethionine | 2023 |
Effects of methylation of arginine residue 83 on the enzymatic activity of human arsenic (+3 oxidation state) methyltransferase.
Topics: Arginine; Arsenic; HEK293 Cells; Humans; Methylation; Methyltransferases; S-Adenosylmethionine | 2023 |
S-adenosylmethionine treatment affects histone methylation in prostate cancer cells.
Topics: DNA Methylation; Histones; Humans; Male; Methylation; Prostatic Neoplasms; Protein Processing, Post-Translational; S-Adenosylmethionine | 2024 |
Histone methyltransferase activity affects metabolism in human cells independently of transcriptional regulation.
Topics: Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Neoplasms; Protein Processing, Post-Translational; S-Adenosylmethionine | 2023 |
MePMe-seq: antibody-free simultaneous m
Topics: Antibodies; Methylation; RNA; RNA, Messenger; S-Adenosylmethionine | 2023 |
Functional characterization of a naphthalene-O-methyltransferase from Nocardia sp. CS682.
Topics: Escherichia coli; Methylation; Methyltransferases; Naphthalenes; Nocardia; S-Adenosylmethionine | 2024 |