isomethyleugenol has been researched along with quercetin in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.70) | 18.7374 |
| 1990's | 7 (12.96) | 18.2507 |
| 2000's | 17 (31.48) | 29.6817 |
| 2010's | 25 (46.30) | 24.3611 |
| 2020's | 3 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Berry, DL; Bracken, WM; Fischer, SM; Miller, DR; Slaga, TJ; Viaje, A | 1 |
| Hamada, J; Hosokawa, M; Ishikawa, M; Kobayashi, H; Okada, F | 1 |
| Das, NP; Kuppusamy, UR | 1 |
| Basnet, P; Hase, K; Kadota, S; Namba, T | 1 |
| Liehr, JG; Zhu, BT | 2 |
| Ezell, EL; Liehr, JG; Zhu, BT | 1 |
| Gauthier, A; Gulick, PJ; Ibrahim, RK | 1 |
| Crespy, V; Demigné, C; Manach, C; Morand, C; Régérat, F; Rémésy, C; Texier, O | 1 |
| Crespy, V; Manach, C; Morand, C; Remesy, C | 1 |
| Dhar, K; Hosny, M; Rosazza, JP | 1 |
| Bennett, RN; DuPont, MS; Mellon, FA; Williamson, G | 1 |
| Azuma, K; Higashio, H; Ippoushi, K; Ito, H; Terao, J | 1 |
| Aura, AM; Bailey, M; Nuutila, AM; O'Leary, KA; Ojala, M; Oksman-Caldentey, KM; Poutanen, K; Puupponen-Pimiä, R; Williamson, G | 1 |
| De Santi, C; Mosca, F; Pacifici, GM; Pietrabissa, A | 1 |
| Cogolludo, AL; Duarte, J; Ibarra, M; López-López, G; Moreno, L; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá-Arnáez, F | 1 |
| Kuhnle, GG; Rice-Evans, C; Spencer, JP; Williams, RJ | 1 |
| Baldwin, IT; Oldham, NJ; Roda, AL; Svatos, A | 1 |
| Kiehlmann, E; Slade, PW | 1 |
| Boersma, MG; Gliszczyńska-Swigło, A; Lemańska, K; Rietjens, IM; Szymusiak, H; Tyrakowska, B; van der Woude, H | 1 |
| Ahn, JH; Hur, HG; Kim, BG; Lee, Y; Lim, Y; Shin, KH | 1 |
| Ahn, JH; Hur, HG; Jung, BR; Kim, BG; Lee, Y; Lim, Y | 1 |
| Alink, GM; Boersma, MG; Rietjens, IM; van der Woude, H; Vervoort, J | 1 |
| Andriantsitohaina, R; Chaabi, M; Freund-Michel, V; Frossard, N; Lobstein, A; Randriantsoa, A | 1 |
| Charro, N; Florencio, MH; Justino, GC; Mira, L; Rodríguez-Gómez, MJ; Santos, MR | 1 |
| Chumanevich, AA; Kopycki, JG; Neumann, P; Rauh, D; Stubbs, MT; Vogt, T | 1 |
| Dueñas, M; González-Manzano, S; González-Paramás, A; Santos-Buelga, C | 1 |
| Duan, JA; Guo, J; Qian, D; Shang, EX; Tang, Y; Xue, C | 1 |
| Ichikawa, S; Ishisaka, A; Ito, M; Kato, Y; Kawai, Y; Miyamoto, K; Nakamura, T; Piskula, MK; Sakakibara, H; Terao, J; Tsuji, A | 1 |
| Cabello, J; Dueñas, M; Gómez-Orte, E; González-Manzano, S; González-Paramás, AM; Santos-Buelga, C; Surco-Laos, F | 1 |
| Heber, D; Henning, SM; Wang, P | 2 |
| Duarte, J; Perez-Vizcaino, F; Santos-Buelga, C | 1 |
| Duan, JA; Li, NG; Shi, ZH; Tang, YP; Yang, JP | 1 |
| Chow, LM; Jiang, T; Liu, T; Wan Sheng, B; Wang, SW; Wen, BJ; Wong, IL; Yuan, J | 1 |
| Benkhaled, M; Haba, H; Laraoui, H; Long, C | 1 |
| Bowles, DJ; Brown, GD; Brown, N; Drummond, RA; Kaye, PM; Lim, EK; Mitchell, PJ | 1 |
| Bae, JS; Hong, M; Jee, JG; Jeong, TC; Lee, MY; Lee, S; Lee, YM; Song, M | 1 |
| Fujikura, Y; Kawamura, T; Matsui, N; Minekawa, S; Mukai, R; Murota, K; Nemoto, H; Terao, J; Uehara, M | 1 |
| Chen, Z; Lin, Z; Lu, M; Lv, H; Ma, C; Shi, J; Zhang, X | 1 |
| Eibl, G; Go, VL; Lu, QY; Zhang, L | 1 |
| Cao, Y; Chen, JZ; Chen, ZJ; Jiang, HD | 1 |
| Duan, JA; Fu, HA; Li, NG; Li, W; Shi, QP; Shi, ZH; Tang, H; Tang, YP; Zhang, X | 1 |
| Ikeda, T; Iwai, K; Nishijima, T; Saito, Y; Takida, Y | 1 |
| Gao, W; Guo, C; Meng, B; Pu, L; Tang, Z; Wei, J | 1 |
| Escribano-Ferrer, E; Lamuela-Raventos, RM; Martínez-Huélamo, M; Orrego-Lagarón, N; Quifer-Rada, P | 1 |
| Barber, D; Cubells-Baeza, N; Díaz-Perales, A; Garrido-Arandia, M; Gómez-Casado, C; Melendi, PG; Pacios, LF; Pozo, JC; Ramírez-Castillejo, C; Silva-Navas, J | 1 |
| Alamdar, A; Eqani, SAMAS; Huang, Q; Shen, H; Tian, M; Xi, G | 1 |
| Bhoo, SH; Cho, MH; Lee, D; Lee, SW; Park, HL | 1 |
| Hara, H; Ikushiro, S; Nishikawa, M; Oyama, M; Tanaka, S | 1 |
| Araki, M; Fujitaka, Y; Hamada, H; Hamadad, H; Ishihara, K; Kubota, N; Nakayama, N; Onishi, T; Shimoda, K; Tanigawa, M | 1 |
| Magar, RT; Sohng, JK | 1 |
| Baiseitova, A; Kim, JH; Kim, JY; Lee, G; Lee, KW; Park, KH; Shah, AB; Zhumanova, K | 1 |
| Bielak-Zmijewska, A; Dudkowska, M; Figiel, I; Gadecka, A; Krzystyniak, A; Mosieniak, G; Petrazzo, G; Sikora, E; Wesierska, M; Wlodarczyk, J | 1 |
1 review(s) available for isomethyleugenol and quercetin
| Article | Year |
|---|---|
A Review on Structure, Modifications and Structure-Activity Relation of Quercetin and Its Derivatives.
Topics: Biotransformation; Escherichia coli; Glycosylation; Glycosyltransferases; Metabolic Engineering; Methylation; Quercetin; Structure-Activity Relationship | 2020 |
1 trial(s) available for isomethyleugenol and quercetin
| Article | Year |
|---|---|
Simultaneous ingestion of high-methoxy pectin from apple can enhance absorption of quercetin in human subjects.
Topics: Adult; Antioxidants; Beverages; Cross-Over Studies; Dietary Supplements; Disaccharides; Fruit; Gastrointestinal Agents; Humans; Hydrolysis; Intestinal Absorption; Male; Malus; Methylation; Pectins; Quercetin; Renal Elimination; Up-Regulation; Viscosity | 2015 |
52 other study(ies) available for isomethyleugenol and quercetin
| Article | Year |
|---|---|
Lack of involvement of 6-hydroxymethylation in benzo[a]pyrene skin tumor initiation in mice.
Topics: Animals; Benzimidazoles; Benzopyrenes; Biotransformation; Female; Flavonoids; Hydroxylation; Methylation; Mice; Neoplasms, Experimental; Papilloma; Quercetin; Skin Neoplasms | 1978 |
Changes in the tumorigenic and metastatic properties of tumor cells treated with quercetin or 5-azacytidine.
Topics: Animals; Azacitidine; Cell Line; DNA; Fibrosarcoma; Flavonoids; Methylation; Mice; Mice, Inbred C57BL; Mutagens; Neoplasm Metastasis; Neoplasm Transplantation; Phenotype; Quercetin | 1987 |
Potentiation of beta-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Flavonoids; Flavonols; Lipolysis; Male; Methylation; Phospholipids; Phosphoric Diester Hydrolases; Quercetin; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1994 |
Matteuorienate A and B, two new and potent aldose reductase inhibitors from Matteuccia orientalis (Hook.) Trev.
Topics: Aldehyde Reductase; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Flavanones; Flavonoids; Lens, Crystalline; Magnetic Resonance Spectroscopy; Methylation; Plant Extracts; Quercetin; Rats; Structure-Activity Relationship | 1994 |
Quercetin increases the severity of estradiol-induced tumorigenesis in hamster kidney.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Catechol O-Methyltransferase; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Drug Synergism; Estradiol; Estrogens, Catechol; Flavonoids; Kidney; Kidney Neoplasms; Male; Mesocricetus; Methylation; Microsomes, Liver; NADP; Oxidation-Reduction; Quercetin; Steroid Hydroxylases | 1994 |
Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo.
Topics: Animals; Biotransformation; Catalysis; Catechol O-Methyltransferase; Catecholamines; Cricetinae; Estrogens; Kinetics; Male; Methylation; Mutagens; Quercetin; S-Adenosylhomocysteine | 1994 |
Inhibition of catechol O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estradiol-induced tumorigenesis.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Cricetinae; Enzyme Inhibitors; Estradiol; Estrogens, Catechol; Flavonoids; Flavonols; Hesperidin; Kidney; Kidney Neoplasms; Kinetics; Male; Mesocricetus; Methylation; Oxidation-Reduction; Quercetin; S-Adenosylhomocysteine | 1996 |
cDNA cloning and characterization of a 3'/5'-O-methyltransferase for partially methylated flavonols from Chrysosplenium americanum.
Topics: Amino Acid Sequence; Blotting, Southern; Caffeic Acids; Catechol O-Methyltransferase; Cloning, Molecular; DNA Primers; DNA, Complementary; Flavonoids; Flavonols; Gene Library; Genes, Plant; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Weight; Plant Proteins; Plants; Polymerase Chain Reaction; Quercetin; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity | 1996 |
Comparison of the bioavailability of quercetin and catechin in rats.
Topics: Animals; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Diet; Glucuronides; Liver; Male; Methylation; Quercetin; Rats; Rats, Wistar; Sulfates | 1999 |
Respective bioavailability of quercetin aglycone and its glycosides in a rat model.
Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Flavonols; Glucuronidase; Glycosides; Glycosylation; Intestinal Absorption; Male; Methylation; Quercetin; Rats; Rats, Wistar; Rhamnose; Rutin; Sulfatases | 2000 |
Hydroxylations and methylations of quercetin, fisetin, and catechin by Streptomyces griseus.
Topics: Catechin; Flavonoids; Flavonols; Hydroxylation; Methylation; Quercetin; Spectrum Analysis; Streptomyces | 2001 |
Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans.
Topics: Absorption; Adult; Alcoholic Beverages; Caffeic Acids; Chromatography, High Pressure Liquid; Female; Flavonoids; Hippurates; Humans; Male; Malus; Methylation; Phenols; Phloretin; Polymers; Quercetin | 2002 |
Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats.
Topics: Animals; Ethanol; Excipients; Glycerol; Hydrolysis; Intestinal Absorption; Kinetics; Lipids; Male; Methylation; Phosphatidylcholines; Polymers; Quercetin; Rats; Rats, Wistar; Solubility; Solutions; Soybean Oil; Sucrose; Taurocholic Acid; Water | 2002 |
Quercetin derivatives are deconjugated and converted to hydroxyphenylacetic acids but not methylated by human fecal flora in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anaerobiosis; Chromatography, High Pressure Liquid; Feces; Fermentation; Humans; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Methylation; Quercetin; Rutin | 2002 |
Methylation of quercetin and fisetin, flavonoids widely distributed in edible vegetables, fruits and wine, by human liver.
Topics: Adult; Aged; Female; Flavonoids; Flavonols; Fruit; Humans; In Vitro Techniques; Kinetics; Liver; Male; Methylation; Middle Aged; Quercetin; Vegetables; Wine | 2002 |
Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries.
Topics: Animals; Aorta; Arteries; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Male; Mesenteric Arteries; Methylation; Muscle Relaxation; Muscle, Smooth, Vascular; Permeability; Potassium Channel Blockers; Quercetin; Rats; Rats, Wistar; Vascular Resistance; Vasodilator Agents | 2002 |
Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites.
Topics: Chromatography, Liquid; Fibroblasts; Humans; Mass Spectrometry; Methylation; Oxidative Stress; Quercetin | 2003 |
Allometric analysis of the induced flavonols on the leaf surface of wild tobacco (Nicotiana attenuata).
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Cyclopentanes; Host-Parasite Interactions; Manduca; Methylation; Nicotiana; Oxylipins; Plant Leaves; Quercetin; Regression Analysis; Spectrometry, Mass, Electrospray Ionization; Stress, Mechanical; Ultraviolet Rays | 2003 |
Methylation of dihydroquercetin acetates: synthesis of 5-O-methyldihydroquercetin.
Topics: Acetates; Flavonols; Indicators and Reagents; Methylation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quercetin; Stereoisomerism | 2003 |
The effect of catechol O-methylation on radical scavenging characteristics of quercetin and luteolin--a mechanistic insight.
Topics: Antioxidants; Apigenin; Catechols; Flavonoids; Free Radical Scavengers; Hydrogen; Hydrogen-Ion Concentration; Kaempferols; Luteolin; Methylation; Molecular Structure; Quercetin | 2004 |
Multiple regiospecific methylations of a flavonoid by plant O-methyltransferases expressed in E. coli.
Topics: Biotransformation; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavonoids; Flavonols; Gene Expression; Genetic Vectors; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Structure; Oryza; Plant Proteins; Quercetin; Transformation, Genetic | 2005 |
Regiospecific flavonoid 7-O-methylation with Streptomyces avermitilis O-methyltransferase expressed in Escherichia coli.
Topics: Amino Acid Sequence; Escherichia coli; Flavanones; Flavonoids; Gene Expression; Genistein; Isoflavones; Kaempferols; Methylation; Methyltransferases; Molecular Sequence Data; Quercetin; Sequence Alignment; Streptomyces | 2006 |
Consequences of quercetin methylation for its covalent glutathione and DNA adduct formation.
Topics: Animals; Antioxidants; DNA Adducts; Glutathione; Horseradish Peroxidase; Methylation; Oxidation-Reduction; Quercetin; Quinones; Rats; Structure-Activity Relationship | 2006 |
Anti-proliferative effect of Euphorbia stenoclada in human airway smooth muscle cells in culture.
Topics: Anti-Asthmatic Agents; Bronchi; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Euphorbia; Glycosylation; Humans; Interleukin-1beta; Madagascar; Mass Spectrometry; Methylation; Muscle, Smooth; Plant Extracts; Quercetin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts | 2007 |
Influence of the metabolic profile on the in vivo antioxidant activity of quercetin under a low dosage oral regimen in rats.
Topics: Animals; Antioxidants; Benzothiazoles; Chromatography, High Pressure Liquid; Glucuronides; Male; Methylation; Quercetin; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfates; Sulfonic Acids; Thiazoles | 2008 |
Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases.
Topics: Acyl Coenzyme A; Amino Acid Sequence; Binding Sites; Caffeic Acids; Catalysis; Chromones; Crystallography, X-Ray; Flavones; Glucose; Glucosides; Magnesium; Mesembryanthemum; Methylation; Molecular Sequence Data; Plant Proteins; Protein Conformation; Protein O-Methyltransferase; Quercetin; Substrate Specificity | 2008 |
Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin.
Topics: Antioxidants; Catechin; Ferric Compounds; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Oxidation-Reduction; Quercetin; Reference Standards | 2010 |
Identification of hyperoside metabolites in rat using ultra performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Glucuronides; Male; Mass Spectrometry; Methylation; Quercetin; Rats; Rats, Sprague-Dawley; Software; Sulfates | 2011 |
Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood-Brain Barrier; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Electrochemical Techniques; Endothelial Cells; Endothelium, Vascular; Glucuronidase; Humans; Male; Methylation; Neurodegenerative Diseases; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Sulfotransferases; Tandem Mass Spectrometry; Tissue Extracts | 2011 |
Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans.
Topics: Animals; Body Temperature Regulation; Caenorhabditis elegans; Disaccharides; Flavonols; Longevity; Methylation; Oxidative Stress; Quercetin | 2011 |
Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo.
Topics: Animals; Biological Availability; Catechin; Catechol O-Methyltransferase; Cell Line, Tumor; Down-Regulation; Humans; Male; Methylation; Mice; Mice, SCID; Neoplasms; Polyphenols; Quercetin; Tea; Up-Regulation | 2012 |
Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells.
Topics: Androgens; Anticarcinogenic Agents; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Male; Methylation; Prostatic Neoplasms; Quercetin; Tea | 2012 |
The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids.
Topics: Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Biological Transport; Blood Vessels; Humans; Hydrolysis; Metabolic Detoxication, Phase II; Methylation; Neuroprotective Agents; Phytotherapy; Plant Extracts; Quercetin; Vasodilator Agents | 2012 |
Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors.
Topics: Animals; Anticoagulants; Blood Coagulation Tests; Chemistry Techniques, Synthetic; Fibrinogen; Male; Methylation; Molecular Docking Simulation; Oxygen; Protein Conformation; Quercetin; Rabbits; Structure-Activity Relationship; Thrombin | 2012 |
Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Resistance, Multiple; Humans; Methylation; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Quercetin | 2012 |
New methylated flavonol glucosides from Fumana montana Pomel.
Topics: Cistaceae; Glucosides; Kaempferols; Methylation; Quercetin | 2013 |
Regiospecific methylation of a dietary flavonoid scaffold selectively enhances IL-1β production following Toll-like receptor 2 stimulation in THP-1 monocytes.
Topics: Caspase 1; Cell Line; Cycloheximide; Drug Synergism; Flavonoids; Gene Expression Regulation; Humans; Interleukin-1beta; Lipopeptides; Methylation; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Phosphorylation; Quercetin; RNA, Messenger; Stereoisomerism; Toll-Like Receptor 2; Transcription, Genetic | 2013 |
Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
Topics: Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Discovery; Enzyme Inhibitors; Galactosides; Herb-Drug Interactions; Humans; Isoenzymes; Kinetics; Methylation; Microsomes, Liver; Oenanthe; Quercetin; Recombinant Proteins | 2013 |
Prenylation enhances quercetin uptake and reduces efflux in Caco-2 cells and enhances tissue accumulation in mice fed long-term.
Topics: Animals; Area Under Curve; Biological Availability; Biological Transport; Caco-2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Intestinal Mucosa; Kidney; Liver; Lymph; Methylation; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Prenylation; Quercetin; Rats; Rats, Wistar | 2013 |
Identification of regioisomers of methylated kaempferol and quercetin by ultra high performance liquid chromatography quadrupole time-of-flight (UHPLC-QTOF) tandem mass spectrometry combined with diagnostic fragmentation pattern analysis.
Topics: Camellia sinensis; Chromatography, High Pressure Liquid; Cycloaddition Reaction; Kaempferols; Methane; Methylation; Methyltransferases; Quercetin; Stereoisomerism; Tandem Mass Spectrometry | 2013 |
Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase.
Topics: Animals; Chromatography, High Pressure Liquid; Dietary Supplements; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glucaric Acid; Glucuronidase; Glucuronides; Glycoproteins; Humans; Lactones; Liver; Liver Neoplasms; Methylation; Mice; Pancreas; Quercetin; Xenograft Model Antitumor Assays | 2014 |
Computational studies of the regioselectivities of COMT-catalyzed meta-/para-O methylations of luteolin and quercetin.
Topics: Binding Sites; Biocatalysis; Catechol O-Methyltransferase; Flavonoids; Humans; Luteolin; Magnesium; Methylation; Molecular Dynamics Simulation; Protein Structure, Tertiary; Quantum Theory; Quercetin; Recombinant Proteins; Stereoisomerism; Thermodynamics | 2014 |
Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Methylation; Molecular Structure; Neoplasms; Quercetin; Structure-Activity Relationship | 2014 |
Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet.
Topics: Animals; Case-Control Studies; Gene Expression; Homocysteine; Male; Metabolic Networks and Pathways; Methionine; Methylation; Quercetin; Rats; Rats, Wistar | 2015 |
Absorption and disposition of naringenin and quercetin after simultaneous administration via intestinal perfusion in mice.
Topics: Algorithms; Animals; Antioxidants; Bile; Dietary Supplements; Flavanones; Glucuronides; Hepatobiliary Elimination; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Kinetics; Methylation; Mice; Models, Biological; Molecular Structure; Perfusion; Quercetin; Solubility; Sulfides | 2016 |
Characterisation of a flavonoid ligand of the fungal protein Alt a 1.
Topics: Allergens; Arabidopsis; Catechols; Flavonoids; Fungal Proteins; Hydrogen-Ion Concentration; Ligands; Methylation; Molecular Docking Simulation; Plant Roots; Quercetin; Spores, Fungal | 2016 |
Arsenic activates the expression of 3β-HSD in mouse Leydig cells through repression of histone H3K9 methylation.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Arsenites; Cell Line; Cell Survival; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Enzyme Inhibitors; Epigenesis, Genetic; Histone Demethylases; Histones; Inhibitory Concentration 50; Leydig Cells; Male; Methylation; Mice; Progesterone; Promoter Regions, Genetic; Quercetin; RNA, Messenger; Sodium Compounds; Testosterone | 2017 |
Biotechnological Production of Dimethoxyflavonoids Using a Fusion Flavonoid O-Methyltransferase Possessing Both 3'- and 7-O-Methyltransferase Activities.
Topics: Escherichia coli; Flavanones; Flavonoids; Luteolin; Methylation; Methyltransferases; Molecular Structure; Quercetin | 2017 |
Simultaneous collection of the portal and superior vena cava blood in conscious rats defined that intestinal epithelium is the major site of glucuronidation, but not sulfation and methylation, of quercetin.
Topics: Administration, Oral; Animals; Blood Specimen Collection; Glucuronides; Glycosides; Intestinal Mucosa; Male; Methylation; Portal Vein; Quercetin; Rats, Wistar; Sulfates; Vena Cava, Superior | 2018 |
Glycosylation and Methylation of Quercetin and Myricetin by Cultured Cells of Phytolacca americana.
Topics: Biotransformation; Cells, Cultured; Flavonoids; Glycosylation; Methylation; Molecular Structure; Phytolacca americana; Quercetin | 2017 |
Inhibitory mechanism of O-methylated quercetins, highly potent β-secretase inhibitors isolated from Caragana balchaschensis (Kom.) Pojark.
Topics: Amyloid Precursor Protein Secretases; Caragana; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Kinetics; Methylation; Molecular Docking Simulation; Plant Components, Aerial; Plant Extracts; Protein Binding; Quercetin; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tandem Mass Spectrometry | 2021 |
Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile.
Topics: Aging; Animals; Cellular Senescence; Cognition; Dasatinib; Hippocampus; Histones; Inflammation; Male; Methylation; Mice; Neuronal Plasticity; Quercetin; Rats; Rats, Wistar | 2022 |