Page last updated: 2024-08-18

isomethyleugenol and proadifen

isomethyleugenol has been researched along with proadifen in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199018 (85.71)18.7374
1990's2 (9.52)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Powis, G1
Hollingworth, RM; Hsu, WH; Smith, BE1
DeMarco, GJ; Howard, PC; McCoy, GD1
Bickel, MH; Willi, P1
Bickel, MH; Gigon, PL1
Ackermann, E1
Feuer, G1
Clark, B; Thompson, JW; Widdrington, G1
Hildebrandt, AG1
Englert, LF; Estevez, VS; Ho, BT1
Chiga, M; Garry, VF; Lopez-Corella, E; Plapp, FV1
Horie, T; Kitada, M; Kitagawa, H1
DiAugustine, RP; Eling, TE1
Aebi, H; Baggiolini, M; Dewald, B1
Nakazawa, K1
Eade, NR; Renton, KW1
Bickel, MH; Weder, HJ1
Juvonen, RO; Kojo, A; Komulainen, H; Liesivuori, J; Pasanen, M; Pennanen, S1
Kim, DH; Lee, DH1
NETTER, KJ1
Tsai, PL; Tsai, TH1

Reviews

1 review(s) available for isomethyleugenol and proadifen

ArticleYear
The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Ethylamines; Hydrogen-Ion Concentration; In Vitro Techniques; Isocitrate Dehydrogenase; Methylation; Metyrapone; Microsomes, Liver; Morphinans; Oxidation-Reduction; Phenobarbital; Proadifen; Pseudomonas; Rats; Spectrum Analysis

1972

Other Studies

20 other study(ies) available for isomethyleugenol and proadifen

ArticleYear
Effect of a single oral dose of methanol, ethanol and propan-2-ol on the hepatic microsomal metabolism of foreign compounds in the rat.
    The Biochemical journal, 1975, Volume: 148, Issue:2

    Topics: 1-Propanol; Acetone; Administration, Oral; Aminopyrine; Aniline Compounds; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport Complex IV; Ethanol; Hydroxylation; Male; Methanol; Methylation; Microsomes, Liver; Proadifen; Rats

1975
The bradycardic and mydriatic effects of chlordimeform and its demethylated analogs in the rat: antagonism by idazoxan but not by prazosin.
    Life sciences, 1988, Volume: 43, Issue:23

    Topics: Amidines; Animals; Chlorphenamidine; Dioxanes; Dioxins; Heart Rate; Idazoxan; Insecticides; Male; Methylation; Prazosin; Proadifen; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1988
Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Cotinine; Cricetinae; Cyanides; Cysteamine; Male; Mesocricetus; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nicotine; Oxidation-Reduction; Papain; Peptide Hydrolases; Proadifen

1986
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. II. N,N-dimethylaniline.
    Archives of biochemistry and biophysics, 1973, Volume: 156, Issue:2

    Topics: Acetates; Aniline Compounds; Animals; Calcium; Depression, Chemical; Edetic Acid; Formaldehyde; Glycols; Kinetics; Magnesium; Male; Methylation; Microsomes, Liver; NADP; Niacinamide; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Species Specificity; Stimulation, Chemical; Sulfhydryl Reagents; Swine

1973
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Feb-08, Volume: 10, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation

1971
[Demethylation of aminophenazone and codeine in human liver. An investigation of microsomal electron transport].
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Aminopyrine; Animals; Codeine; Cyanides; Cytochromes; Dealkylation; Electron Spin Resonance Spectroscopy; Electron Transport; Female; Glucosephosphate Dehydrogenase; Half-Life; Humans; Kinetics; Lysosomes; Male; Mathematics; Methylation; Microsomes, Liver; Middle Aged; Mitochondria, Liver; NADP; Niacinamide; Oxidoreductases; Pentosephosphates; Phosphogluconate Dehydrogenase; Proadifen; Rats; Sex Factors; Species Specificity; Spectrophotometry

1970
3-Hydroxylation of coumarin or 4-methylcoumarin by rat-liver microsomes and its induction by 4-methylcoumarin given orally.
    Chemico-biological interactions, 1970, Volume: 2, Issue:3

    Topics: Animals; Coumarins; Dactinomycin; Enzyme Induction; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; NAD; NADP; Phospholipases; Proadifen; Proteins; Rats; Surface-Active Agents

1970
Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man.
    British journal of pharmacology, 1972, Volume: 44, Issue:1

    Topics: Amphetamine; Animals; Chlorpromazine; Desipramine; Drug Interactions; Histamine; Hydrazines; Hydrocortisone; Imipramine; Iproniazid; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nialamide; Opipramol; Phenothiazines; Phenylhydrazines; Prednisolone; Proadifen; Promazine; Rats; Transferases

1972
A new methylated metabolite of (-)-11-hydroxy-delta 8-tetrahydrocannabinol in rats.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:3

    Topics: Animals; Brain; Cannabis; Chromatography, Thin Layer; Dronabinol; Hydrolysis; Liver; Male; Methyl Ethers; Methylation; Proadifen; Rats; Tritium

1973
Different effects of pretreatment with 2-diethylaminoethyl-2,2-diphenylvalerate on the mouse liver polysomal disaggregation by dimethylnitrosamine and lasiocarpine.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 3, Issue:1

    Topics: Adhesiveness; Alkaloids; Animals; Biotransformation; Centrifugation, Density Gradient; Dealkylation; Drug Interactions; Heterocyclic Compounds; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Nitrosamines; Proadifen; Pyrrolizidine Alkaloids; Ribosomes

1972
Studies on drug metabolism. 13. Possible role of liver microsomal cytochrome P-450 in the oxidative N-demethylation of p-substituted dimethylaniline, N-methyl-N-alkylaniline and N-methyl-N-acylaniline derivatives.
    Chemical & pharmaceutical bulletin, 1972, Volume: 20, Issue:4

    Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Male; Methylation; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains

1972
A role for phospholipids in the binding and metabolism of drugs by hepatic microsomes. Use of the fluorescent hydrophobic probe 1-anilinonaphthalene-8-sulphonate.
    The Biochemical journal, 1971, Volume: 123, Issue:4

    Topics: Aniline Compounds; Animals; Benzphetamine; Ethylamines; Fluorescence; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Naphthalenes; Pharmaceutical Preparations; Phosphatidylcholines; Phospholipases; Phospholipids; Proadifen; Rats; Receptors, Drug; Spectrophotometry; Sulfonic Acids; Trypsin; Warfarin

1971
N-demethylation of p-(N1-methylhydrazion methyl)-N-isopropyl benzamide (procarbazine), a cytostatically active methylhydrazine derivative, in the intact rat and in the isolated perfused rat liver.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Benzoates; Carbon Dioxide; Carbon Isotopes; Hydrazines; Liver; Male; Methylation; Methylcholanthrene; Oxidation-Reduction; Perfusion; Phenobarbital; Proadifen; Rats

1969
Studies on the demethylation, hydroxylation and N-oxidation of imipramine in rat liver.
    Biochemical pharmacology, 1970, Volume: 19, Issue:4

    Topics: Amino Alcohols; Animals; Carbon Isotopes; Chlorides; Chromatography, Paper; Dealkylation; Desipramine; Ethylamines; Imipramine; Liver; Magnesium; Male; Metabolism; Methylation; Oxidation-Reduction; Oxides; Phenobarbital; Proadifen; Rats; Valerates

1970
Effect of monoamine oxidase inhibitors on the N-demethylation and hydrolysis of meperidine.
    Biochemical pharmacology, 1970, Volume: 19, Issue:7

    Topics: Amphetamine; Animals; Dealkylation; Dextroamphetamine; Ethanol; Hydrolysis; In Vitro Techniques; Iproniazid; Kinetics; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Proadifen; Rats; Statistics as Topic; Stereoisomerism; Tranylcypromine

1970
Demethylation of imipramine in the rat as influenced by SKF 525-A and by different routes of administration.
    Life sciences, 1968, Nov-01, Volume: 7, Issue:21

    Topics: Animals; Brain Chemistry; Female; Imipramine; In Vitro Techniques; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Methylation; Proadifen; Rats

1968
CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: Aged; Animals; Antibodies, Monoclonal; Caproates; Cytochrome P-450 Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Male; Methylation; Metyrapone; Mice; Microsomes, Liver; Middle Aged; NADPH-Ferrihemoprotein Reductase; Occupational Exposure; Proadifen; Quinidine; Rats; Rats, Wistar; Troleandomycin

1996
S-methylation of 2-mercaptopyrazine in rat liver microsomes and cytosol.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:9

    Topics: Aniline Compounds; Animals; Benzylamines; Chlorobenzoates; Cytosol; Enzyme Inhibitors; Male; Methylation; Methyltransferases; Microsomes, Liver; Proadifen; Pyrazines; Rats; Rats, Sprague-Dawley; Vanillic Acid

1999
[A method for the direct measurement of O-demethylation in liver microsomes and its use in studying microsome inhibition by SKF-525-A].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1960, Volume: 238

    Topics: Fatty Acids; Humans; Liver; Methylation; Microsomes; Microsomes, Liver; Proadifen

1960
Hepatobiliary excretion of berberine.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Berberine; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glucuronides; Half-Life; Injections, Intravenous; Liver; Male; Methylation; Microdialysis; Organic Cation Transport Proteins; Proadifen; Probenecid; Quinidine; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Time Factors

2004