Page last updated: 2024-08-18

isomethyleugenol and nortriptyline

isomethyleugenol has been researched along with nortriptyline in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's6 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coppen, A; Rao, VA1
Horn, AS; Trace, RC1
Borgå, O; Garle, M1
von Bahr, C1
Ahtee, L; Paasonen, MK1
Bertilsson, L; Sjöqvist, F1
Ettigi, P; Friedel, RO; Joseph, A; Narasimhachari, N; Saady, JJ1
Robins, E; Rudorfer, MV1
Morita, S; Noguchi, T; Ozeki, Y; Shibasaki, M; Shimoda, K; Someya, T; Takahashi, S1
Wahba, WW; Winek, CL; Zaveri, NR1
Breyer-Pfaff, U; Nill, K1
Jenkins, AJ; Jufer, R; Levine, B; Queen, M; Smialek, JE1
Ellis, SW; Ghahramani, P; Lennard, MS; Ramsay, LE; Tucker, GT1
Linnet, K; Olesen, OV1

Reviews

1 review(s) available for isomethyleugenol and nortriptyline

ArticleYear
Clinical pharmacology of antidepressant drugs: pharmacogenetics.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Depressive Disorder; Female; Genetic Variation; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Methylation; Middle Aged; Nortriptyline; Pharmacogenetics; Pregnancy; Twins, Dizygotic; Twins, Monozygotic

1984

Other Studies

13 other study(ies) available for isomethyleugenol and nortriptyline

ArticleYear
Amitriptyline and its demethylation-rate.
    Lancet (London, England), 1979, Jan-06, Volume: 1, Issue:8106

    Topics: Amitriptyline; Biological Availability; Dose-Response Relationship, Drug; Humans; Methylation; Nortriptyline

1979
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes

1974
A gas chromatographic method for the quantitative determination of notriptyline and some of its metabolites in human plasma and urine.
    Journal of chromatography, 1972, May-31, Volume: 68, Issue:1

    Topics: Anhydrides; Chromatography, Gas; Cyclization; Humans; Hydrolysis; Hydroxylation; Indicators and Reagents; Methods; Methylation; Nortriptyline; Solvents

1972
Binding and oxidation of amitriptyline and a series of its oxidized metabolites in liver microsomes from untreated and phenobarbital-treated rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:3

    Topics: Amitriptyline; Animals; Chromatography, Gas; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Male; Mass Spectrometry; Methylation; Microsomes, Liver; Nortriptyline; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Stimulation, Chemical; Structure-Activity Relationship; Time Factors

1972
Potentiation of 5-hydroxytryptamine release from platelets by desmethylation of chlorpromazine and related agents.
    Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:3

    Topics: Amitriptyline; Animals; Blood Platelets; Chlorpromazine; Drug Synergism; Imipramine; Methylation; Nortriptyline; Rabbits; Serotonin

1968
Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amitriptyline; Biotransformation; Depressive Disorder; Desipramine; Humans; Imipramine; Methylation; Nortriptyline

1982
Fatal nortriptyline overdose, plasma levels, and in vivo methylation of tricyclic antidepressants.
    The American journal of psychiatry, 1981, Volume: 138, Issue:7

    Topics: Adult; Amitriptyline; Biotransformation; Chromatography, Gas; Female; Humans; Mass Spectrometry; Methylation; Nortriptyline; Suicide

1981
Interindividual variations of desmethylation and hydroxylation of amitriptyline in a Japanese psychiatric population.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Adult; Aged; Amitriptyline; Biotransformation; Dose-Response Relationship, Drug; Female; Humans; Hydroxylation; Japan; Male; Mental Disorders; Methylation; Middle Aged; Nortriptyline

1995
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
    Forensic science international, 1993, Volume: 61, Issue:2-3

    Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation Studies as Topic; Forensic Medicine; Formaldehyde; Humans; Imipramine; Liver; Methylation; Nortriptyline; Poisoning; Temperature; Time Factors

1993
Stereoselective reversible ketone formation from 10-hydroxylated nortriptyline metabolites in human liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:12

    Topics: Adult; Aged; Biotransformation; Child; Cytosol; Female; Humans; Hydroxylation; Kinetics; Liver; Male; Methylation; Microsomes, Liver; Middle Aged; NADP; Nortriptyline; Oxidation-Reduction; Stereoisomerism

1995
Distribution of venlafaxine in three postmortem cases.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:6

    Topics: Acetaminophen; Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Bile; Chlordiazepoxide; Chromatography, Gas; Cyclohexanols; Diphenhydramine; Humans; Kidney; Liver; Male; Methylation; Middle Aged; Nortriptyline; Reference Standards; Selective Serotonin Reuptake Inhibitors; Suicide; Venlafaxine Hydrochloride

1996
Cytochromes P450 mediating the N-demethylation of amitriptyline.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:2

    Topics: Amitriptyline; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Methylation; Microsomes, Liver; Nortriptyline

1997
Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isozymes.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Isoenzymes; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nortriptyline

1997