isomethyleugenol has been researched along with homocysteine in 461 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 164 (35.57) | 18.7374 |
| 1990's | 65 (14.10) | 18.2507 |
| 2000's | 139 (30.15) | 29.6817 |
| 2010's | 77 (16.70) | 24.3611 |
| 2020's | 16 (3.47) | 2.80 |
| Authors | Studies |
|---|---|
| Brock, ML; Lodish, HF; Rose, JK | 1 |
| Huppert, J; Jacquemont, B | 1 |
| Lawrence, F; Pierré, A; Richou, M; Robert-Géro, M; Vigier, P | 1 |
| Hershfield, MS; Kredich, NM | 2 |
| Furuichi, Y | 1 |
| Mertens, PP; Payne, CC | 1 |
| Benesh, FC; Carl, GF | 1 |
| Mudd, SH | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR | 1 |
| Johnston, JM; Kredich, NM | 1 |
| Labadie, P | 1 |
| Coward, JK; Lesko, N; Michelot, RJ; Stout, RW | 1 |
| Gaull, GE; Niemann, WH; Sturman, JA | 1 |
| Cox, R; Irving, CC; Prescott, C | 1 |
| Lin, RL; Narasimhachari, N | 1 |
| Beaton, JM | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH | 1 |
| Jaszewski, B; Skupin, J; Warchalewski, J | 1 |
| Hamdy, MK; Noyes, OR | 1 |
| Chang, CD; Coward, JK | 2 |
| Fujishima, Y; Ozawa, K; Segawa, T | 1 |
| Miller, JW; Selhub, J | 1 |
| Carney, DF; Papadimitriou, JC; Shin, ML | 1 |
| Fraher, LJ; McFadden, RG | 1 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Baker, DH; Czarnecki, GL | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 2 |
| Lefort, J; Randon, J; Vargaftig, BB | 1 |
| Szpirer, C; Vanhamme, L | 1 |
| Daino, L; Feo, F; Garcea, R; Pascale, R; Puddu, M; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Gharib, A; Greenland, T; Hamidi, J; Khatchadourian, C; Menezo, Y; Sarda, N | 1 |
| Vance, DE; Yao, ZM | 1 |
| Borchardt, RT; Hasobe, M; McKee, JG | 1 |
| Allen, PT; Hernandez, L; Lijinsky, W; Poirier, LA | 1 |
| Pike, MC; Snyderman, R | 3 |
| Fronko, GE; Henderson, EE; Lindemeyer, RG; Long, WK; Wu, B | 1 |
| Carreau, S; Drosdowsky, MA; Kamtchouing, P; Papadopoulos, V | 1 |
| Agostini, S; Cantoni, GL; Kafri, T; Levine, A; Razin, A | 1 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Deussen, A; Lloyd, HG; Schrader, J; Wuppermann, H | 1 |
| Ariyoshi, S; Ichida, S; Okazaki, Y; Sobue, K; Tanaka, T; Yoshioka, K | 1 |
| Bardin, CW; Miller, RL; Tezon, J | 1 |
| Stipanuk, MH | 1 |
| Ghag, S; Kiechle, FL; Sykes, E | 1 |
| Ichida, S | 1 |
| Clarke, S; Lou, LL | 1 |
| Silverstein, SC; Sung, SJ | 1 |
| Samet, MK | 1 |
| Carson, DA; Iizasa, T | 1 |
| Brovold, AB; Hetland, O; Prydz, H | 1 |
| Salama, AI; Saller, CF | 1 |
| Lechner, J; Sumper, M; Wieland, F | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 2 |
| Hirayama, T; Kato, I; Matsuda, F; Noda, M | 1 |
| Cantoni, GL | 1 |
| Gill, MW; Schatz, RA | 1 |
| Carnegie, PR; Jones, GM | 1 |
| Lin, JK; Miller, EC; Miller, JA | 1 |
| Nath, MC; Nath, N | 1 |
| Kerr, SJ | 1 |
| Baxter, CS; Byvoet, P | 2 |
| Banerjee, AK; Moyer, SA; Rhodes, DP | 1 |
| Freeman, JM; Mudd, SH | 1 |
| Bradley, PB; Briggs, I | 1 |
| Grabow, WO | 1 |
| Rüdiger, H | 2 |
| Smith, DA; Whitehouse, JM | 1 |
| Blanchard, P; Farrugia, G; Hildesheim, J; Hildesheim, R; Michelot, R | 1 |
| Balish, E | 1 |
| Finkelstein, JD | 2 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Foster, MA; Salem, AR | 1 |
| Baudry, M; Chast, F; Schwartz, JC | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Sharma, DC | 1 |
| Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL | 1 |
| Taylor, RT; Weissbach, H | 4 |
| Burton, E; Sakami, W; Selhub, J | 1 |
| Schlenk, F; Zappia, V; Zydek-Cwick, R | 1 |
| Childs, JD; Smith, DA | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Taylor, RT | 3 |
| Hanna, ML; Taylor, RT | 1 |
| Landner, L | 1 |
| Bertilsson, L; Neujahr, HY | 1 |
| Lombardini, JB; Talalay, P | 1 |
| Smith, DA | 1 |
| Calhoun, DH; Feary, TW | 1 |
| Akamatsu, Y; Law, JH | 1 |
| Coward, JK; Sweet, WD | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH; Shih, VE; Uhlendorf, BW | 1 |
| Draper, MW; Mangum, JH; North, JA | 1 |
| Coward, JK; D'Urso-Scott, M; Sweet, WD | 1 |
| Breitmaier, E; Flohé, L; Günzler, WA; Jung, G; Voelter, W | 1 |
| Barness, LA; Morrow, G | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 2 |
| McBride, BC; Wolfe, RS | 1 |
| Hochberg, A; Rahat, M | 1 |
| Giec, A; Jankowska, E; Jaszewski, B; Skupin, J | 1 |
| Schlenk, F; Zydek-Cwick, CR | 1 |
| Mahoney, MJ; Mudd, SH; Rosenberg, LE; Uhlendorf, BW | 1 |
| Kjellin-Stråby, K | 1 |
| Foster, MA; Salem, AR; Wilson, RH | 1 |
| Fujii, K; Fukui, S | 1 |
| Barchas, J; Deguchi, T | 1 |
| Demain, AL; White, RF | 1 |
| Sovik, O | 1 |
| Pittoni, A; Rubaltelli, FF; Sussi, PL | 1 |
| Botsford, JL; Parks, LW | 1 |
| Romstedt, K | 1 |
| Ebert, MH; Mudd, SH; Scriver, CR | 1 |
| Glazer, RI; Hartman, KD | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Ahl, R | 1 |
| Baglioni, C; de Ferra, F | 1 |
| Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM | 1 |
| Dev, VG; Mixon, JC | 1 |
| Albers, RJ; Camper, SA; Coward, JK; Rottman, FM | 1 |
| Hoffman, RM | 1 |
| Bardin, CW; Gagnon, C | 1 |
| Robert-Géro, M; Vedel, M | 1 |
| Tisdale, MJ | 2 |
| Mizel, D; Pick, E | 1 |
| Hattori, H; Kanfer, JN | 1 |
| Barak, AJ; Tuma, DJ | 1 |
| Best, L; Garcia-Morales, P; Herchuelz, A; Hubinont, C; Juvent, M; Lebrun, P; Malaisse, WJ; Malaisse-Lagae, F; Saceda, M; Valverde, I | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Rutledge, CO; Samet, MK | 1 |
| Barber, JR; Clarke, S | 1 |
| Awad, WM; Mangum, JH; Skiba, WE; Wells, MS; Whitney, PL | 1 |
| Jaiswal, RK; Landon, EJ; Sastry, BV | 1 |
| Chignard, M; Dray, F; Lecompte, T; Randon, J; Vargaftig, BB | 1 |
| Gregor, P; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE | 1 |
| Chignard, M; Jacquemin, C; Touqui, L; Vargaftig, BB; Wal, F | 1 |
| Chignard, M; Dray, F; Lecompte, T; Marlas, G; Randon, J; Siess, W; Vargaftig, BB | 1 |
| Chignard, M; Marlas, G; Randon, J; Vargaftig, BB | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Tatter, SB | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Barak, AJ; Kemmy, RJ; Tuma, DJ | 1 |
| Fowler, B | 1 |
| Schanche, JS; Schanche, T; Ueland, PM | 1 |
| Meizel, S | 1 |
| Schatz, RA; Sellinger, OZ; Wilens, TE | 2 |
| Gupta, KC; Roy, P | 1 |
| Bynum, JW | 1 |
| Hoffman, JL | 1 |
| Ubbink, JB | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 2 |
| Gottfries, CG; Johansson, BV; Regland, B | 1 |
| Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Scott, JM; Weir, DG | 1 |
| Boers, GH; Janssen, MJ; Stehouwer, CD; van den Berg, M | 1 |
| Croteau, S; Menezo, Y | 1 |
| Bergmann, S; Lehmann, V; Ratter, F; Schiemann, S; Schulze-Osthoff, K; Shatrov, V | 1 |
| Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM | 1 |
| Christensen, B; Chu, RC; Rosenblatt, DS; Ueland, PM | 1 |
| Miller, JW; Nadeau, MR; Selhub, J; Smith, D; Smith, J | 1 |
| Drummond, JT; Matthews, RG | 1 |
| Rees, MM; Rodgers, GM | 1 |
| Christensen, B; Ueland, PM | 1 |
| Abell, C; Alefounder, PR; Battersby, AR; Hädener, A; Louie, GV; Malashkevich, VN; Matzinger, PK; Oliver, P; Pitt, AR; Wood, SP | 1 |
| Jakubowski, H | 1 |
| Ganther, HE; Goeger, DE | 1 |
| Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G | 1 |
| González-Fernández, M; Rey de Viñas, JL; Sandoval, MC | 1 |
| Allen, RH; Buring, JE; Gaziano, JM; Hennekens, CH; Kok, FJ; Reynolds, RD; Stabler, SP; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Jordan, PP; Loehrer, FM; Ritz, R | 1 |
| Blom, HJ; Bökkerink, JP; De Abreu, RA; Keuzenkamp-Jansen, CW; Trijbels, JM | 1 |
| Connell, A; Lobley, GE; Revell, D | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Girgis, S; Jolivet, J; Stover, PJ; Suh, JR | 1 |
| Bottiglieri, T | 2 |
| Goulding, CW; Matthews, RG; Postigo, D | 1 |
| Aletta, JM; Cimato, TR; Ettinger, MJ; Zhou, X | 1 |
| Boiocchi, M; Corona, G; Donada, C; Fabris, M; Toffoli, G; Viel, A; Zarrelli, A | 1 |
| Haber, E; Lai, K; Lee, ME; Perrella, MA; Tsai, JC; Wang, H; Yoshizumi, M | 1 |
| Fiskerstrand, T; Refsum, H; Ueland, PM | 1 |
| Brosnan, JT; Brosnan, ME; House, JD | 2 |
| Bottiglieri, T; Lowenthal, D; Parnetti, L | 1 |
| De Santo, NG; Ingrosso, D; Perna, AF | 1 |
| Goulding, CW; Matthews, RG | 2 |
| Brunone, M; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Aubard, Y; Baudet, JH; Chinchilla, AM; Piver, P | 1 |
| Angst, CP; Brunner, FP; Fowler, B; Haefeli, WE; Loehrer, FM | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Eskes, TK | 1 |
| Boddie, AM; Dembure, PP; Elsas, LJ; Fisher, AJ; Macmahon, W; Saxe, D; Steen, MT; Sullivan, KM | 1 |
| Tam, JP; Yu, Q | 1 |
| Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
| Cattaneo, M; Lecchi, A; Lombardi, R; Zighetti, ML | 1 |
| Cattaneo, M | 1 |
| Achón, M; Alonso-Aperte, E; Pérez-Miguelsanz, J; Ubeda, N; Varela-Moreiras, G | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Albanes, D; Hartman, TJ; Nieto, FJ; Rautalahti, M; Sehlub, J; Stolzenberg-Solomon, RZ; Tangrea, JA; Taylor, PR; Virtamo, J | 1 |
| Berger, R; De Meer, K; Dijkstra, DA; Donker, AJ; Jakobs, C; Kulik, W; Reijngoud, DJ; Stehouwer, CD; van Guldener, C | 1 |
| Brosnan, JT; Brosnan, ME; House, JD; Jacobs, RL; Stead, LM | 1 |
| Mills, JL | 1 |
| Cornelis, R; De Kimpe, J; Vanholder, R | 1 |
| Dudman, NP; Elsworth, GR; Guo, XW; Kelly, FD; Li, D; Mann, NJ; Sinclair, AJ; Wilson, AK | 1 |
| Ashizawa, K; Miyamoto, M; Tsuzuki, Y | 1 |
| Ron, A; Sasson, SB; Wolfe, J | 1 |
| de Meer, K; Jakobs, C; Kok, RM; Kulik, W | 1 |
| Cuskelly, GJ; Gregory, JF; Martinez, M; Toth, JP; Williamson, J | 1 |
| Ebenstein, D; Fukagawa, NK; Martin, JM; O'Rourke, B; Prue, AH; Wurthmann, A | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| Law, MR; Wald, NJ | 1 |
| Rozen, R | 1 |
| Briddon, A; Patel, N | 1 |
| Cook, RJ | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Shane, B; Stacpoole, PW; Toth, JP | 1 |
| Castaldo, P; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF | 1 |
| Stam, F; Stehouwer, CD; van Guldener, C | 1 |
| Eilders, LL; Patel, BP; Sims, M; Waddell, TG | 1 |
| Bandarian, V; Matthews, RG | 1 |
| Castaldo, P; Cimmino, A; De Santo, NG; di Carlo, E; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Ashihara, H; Crozier, A; Kato, A; Koshiishi, C; Yama, S | 1 |
| Amores-Sánchez, MI; Medina, M; Urdiales, JL | 1 |
| Fischer, JA; McCann, MP; Snetselaar, KM | 1 |
| Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Herrmann, W | 1 |
| Au, KP; Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM | 1 |
| Fohr, I; Pietrzik, K; Prinz-Langenohl, R | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Stacpoole, PW; Williamson, J | 1 |
| Bagley, PJ; Jacques, PF; Kalmbach, R; Rogers, G; Rosenberg, IH; Russo, GT; Selhub, J; Wilson, PW | 1 |
| Bottiglieri, T; Di Rocco, A; Geraci, A; Godbold, J; Morgello, S; Simpson, D; Werner, P | 1 |
| Arroo, RR; Baguet, E; Garlick, AP; Girard, S; Lebreton, J; Mesnard, F; Ratcliffe, G; Robins, RJ; Roscher, A | 1 |
| Stock, JB; Vafai, SB | 1 |
| Díaz, M; Freixas, E; Schiel, A; Trimarchi, H | 1 |
| Chiang, EP; Herbig, K; Hills, J; Lee, LR; Shane, B; Stover, PJ | 1 |
| Hoffer, LJ | 2 |
| Coetzee, GA; Laird, PW; Ong, CN; Trinh, BN; Yu, MC | 1 |
| de Meer, K; Finglas, P; Smulders, Y; Stam, F; Stehouwer, CD; van den Akker, JT | 1 |
| Barbaux, S; Doolin, MT; Hoess, K; McDonnell, M; Mitchell, LE; Whitehead, AS | 1 |
| Junker, E; Lauterburg, BH; Russmann, S | 1 |
| Brosnan, JT; Brosnan, ME; Noga, AA; Stead, LM; Vance, DE; Zhao, Y | 1 |
| Loscalzo, J | 2 |
| Blom, HJ; Kluijtmans, LA; Lievers, KJ | 1 |
| Mattson, MP; Shea, TB | 1 |
| Ball, RO; Cole, DE; Di Buono, M; Pencharz, PB; Wykes, LJ | 1 |
| Mason, JB | 1 |
| Beilin, LJ; Burke, V; Croft, KD; Hodgson, JM; Puddey, IB | 1 |
| Lökk, J | 1 |
| Banerjee, R; Oltean, S | 1 |
| Ji, C; Kaplowitz, N | 1 |
| Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G | 1 |
| Bandarian, V; Ludwig, ML; Matthews, RG | 1 |
| Agellon, LB; Altarejos, JY; Shields, DJ; Vance, DE; Wang, X | 1 |
| Bagley, PJ; Lathrop Stern, L; Nadeau, M; Selhub, J; Shane, B; Shih, V | 1 |
| SAKAMI, W; UKSTINS, I | 1 |
| GOLD, M; HURWITZ, J | 1 |
| Bailey, LB; Coats, BS; Davis, SR; Gregory, JF; Kick, LS; Quinlivan, EP; Shane, B; Stacpoole, PW; Williamson, J | 1 |
| Blacquire, KD; Leanza, CM; Miller, RR; Phillips, EE | 1 |
| Davis, SR; Gregory, JF; Mackey, AD; Townsend, JH | 1 |
| Garber, M; Hai, CM; Harrington, EO; Hirase, T; Lu, Q; Newton, J; Rounds, S | 1 |
| Di Rocco, A; Werner, P | 1 |
| Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM | 2 |
| de Meer, K; Jakobs, C; Kulik, W; Smith, DE; Stam, F; Stehouwer, CD; ter Wee, PM; van Guldener, C | 1 |
| Barve, S; Chen, T; Kang, YJ; McClain, CJ; Song, Z; Uriarte, S; Wang, L; Zhou, Z | 1 |
| Benner, J; Chin, HG; Estève, PO; Jacobsen, SE; Patnaik, D; Pradhan, S | 1 |
| Pilgeram, L | 1 |
| De Vriese, AS; Taes, YE | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| de Meer, K; Jakobs, C; Stam, F; Stehouwer, CD; Ter Wee, PM; van Guldener, C | 1 |
| Alberto, JM; Ayav, A; Barbe, F; Brunaud, L; Gerard, P; Gueant, JL; Merten, M | 1 |
| Cacciapuoti, G; Concilio, L; Forte, S; Graziano, G; Merlino, A; Moretti, MA; Porcelli, M | 1 |
| de Meer, K; Jakobs, C; Smulders, YM; Stam, F; Stehouwer, CD; van Guldener, C | 1 |
| de Meer, K; Jakobs, C; Kenemans, P; Kulik, W; Smolders, RG; van der Mooren, MJ | 1 |
| da Costa, KA; Fischer, LM; Gaffney, CE; Zeisel, SH | 1 |
| Chen, J; Handy, DE; Huang, P; Loscalzo, J; Scolaro, J | 1 |
| Coats, BS; Davis, SR; Gregory, JF; Quinlivan, EP; Scheer, JB; Stacpoole, PW | 1 |
| Choi, SW; Corrocher, R; Friso, S; Girelli, D; Guarini, P; Olivieri, O; Pignatti, PF; Trabetti, E | 1 |
| Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C | 1 |
| Charlton, CG; Chen, H; Lee, ES; Soliman, KF | 1 |
| Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
| Bulfer, S; Collazo, E; Couture, JF; Trievel, RC | 1 |
| Brosnan, JT; Brosnan, ME; Devlin, C; Jacobs, RL; Stead, LM; Tabas, I; Vance, DE | 1 |
| Blasco, C; Caballería, J; Deulofeu, R; Gual, A; Lligoña, A; Lluis, JM; Parés, A; Rodés, J | 1 |
| Afman, LA; Blom, HJ; Brouns, MR; Drittij, MJ; van Straaten, HW | 1 |
| Bapteste, E; Biran, D; Doolittle, WF; Gophna, U; Ron, EZ | 1 |
| Smulders, YM; Stehouwer, CD | 1 |
| Blom, HJ; den Heijer, M; Gellekink, H; Heil, SG | 1 |
| Stehouwer, CD; van Guldener, C | 1 |
| Afman, LA; Brouns, MR; Hekking, JW; Köhler, ES; van Straaten, HW; Vanhauten, BA | 1 |
| Coracina, A; Garibotto, G; Kiwanuka, E; Tessari, P; Valerio, A; Vedovato, M; Vettore, M; Zaramella, M | 1 |
| Acanfora, F; Capasso, R; Ingrosso, D; Lombardi, C; Perna, AF; Satta, E | 1 |
| Herrmann, W; Obeid, R | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I | 1 |
| Beers, KW; Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Lawson-Yuen, A; Levy, HL | 1 |
| Toohey, JI | 1 |
| Bald, E; Turski, WA | 1 |
| Ingenbleek, Y | 1 |
| Maloney, CA; Rees, WD; Wilson, FA | 1 |
| Botha, J; Erasmus, RT; Haug, P; Hendricks, M; Hon, D; Kotze, MJ; Kuyler, J; Matsha, T; Potocnik, FC; van Rensburg, SJ | 1 |
| Hasegawa, H; Hashimoto, T; Ogawa, K; Shinohara, Y; Tagoku, K | 1 |
| Molloy, AM | 1 |
| Blom, HJ; den Heijer, M; Finnell, RH; Shaw, GM | 1 |
| Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Blom, HJ; Borm, GF; den Heijer, M; Hermus, AR; Keijzer, MB; Ueland, PM; Vollset, SE | 1 |
| Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Blouet, C; Daré, S; Hammiche, A; Huneau, JF; Mariotti, F; Tomé, D | 1 |
| Hartz, CS; Schalinske, KL | 1 |
| Ahsan, H; Chen, Y; Factor-Litvak, P; Gamble, MV; Graziano, JH; Ilievski, V; Levy, D; Liu, X; Parvez, F; Pilsner, JR; Slavkovich, V | 1 |
| Hermes, M; Kloor, D; Osswald, H | 1 |
| Badaloo, A; Forrester, T; Jahoor, F; Reid, M | 1 |
| Colombatto, S; Grillo, MA | 1 |
| Burrin, DG; Chacko, S; Riedijk, MA; Schierbeek, H; Stoll, B; Sunehag, AL; van Goudoever, JB | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Diaz-Arrastia, R; Lentz, SR; Nunbhakdi-Craig, V; Ogris, E; Sontag, E; Sontag, JM | 1 |
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| Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN | 1 |
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| de Jonge, R; de Vries, JH; Looman, CW; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; Vujkovic, M; Wildhagen, MF | 1 |
| Alberto, JM; Brachet, P; Garcia, MM; Guéant, JL; Guéant-Rodriguez, RM; Gueguen, N; Herrmann, M; Jeannesson, E; Juillière, Y; Lacolley, P; Malthiery, Y; Marie, PY; Maskali, F; Pooya, S | 1 |
| Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K | 1 |
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| Gong, XJ; Guo, M; Jing, LX; Li, D; Lun, YZ; Sun, SX; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS | 1 |
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| Buset-Ríos, N; García-Bello, MA; Hernández-Trujillo, Y; Hernández-Velázquez, E; Rodríguez-Esparragón, F; Rodríguez-Pérez, JC; Serna-Gómez, JA | 1 |
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| Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ | 1 |
| Banasiuk, R; Banecka-Majkutewicz, Z; Banecki, B; Grabowski, M; Kędzierska, B; Lica, J; Węgrzyn, A | 1 |
| Beck, B; Bossenmeyer-Pourié, C; Guéant, JL; Helle, D; Jeannesson, E; Koziel, V; Pourié, G | 1 |
| Gong, T; Jia, SJ; Lai, YQ; Zhang, BK; Zhao, M | 1 |
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| Alberto, JM; Daval, JL; El Hajj Chehadeh, S; Guéant, JL; Leininger-Muller, B; Martin, N; Pourié, G | 1 |
| Blom, HJ; Castro, R; Davids, M; Esse, R; Florindo, C; Gupta, S; Imbard, A; Kruger, WD; Quinlivan, EP; Tavares de Almeida, I; Teerlink, T | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Barroso, M; Blom, HJ; Carlson, BA; Castro, R; de Almeida, IT; Florindo, C; Gladyshev, VN; Handy, DE; Hatfield, DL; Kalwa, H; Loscalzo, J; Michel, T; Silva, Z; Turanov, AA | 1 |
| French, SW; Kharbanda, KK; Orlicky, DJ; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Ostojic, SM | 2 |
| Chen, J; Gao, J; Xu, L; Yang, P; Yu, H | 1 |
| Blanco-González, E; Cinti, M; Fernández de la Campa, MR; Iglesias González, T; Montes-Bayón, M | 1 |
| Cirino, G; Di Minno, A; Di Minno, G; Franchini, M; Lupoli, R; Sorrentino, R; Spadarella, G | 1 |
| Hou, FF; Lei, W; Li, S; Liu, Z; Long, Y; Nie, J; Zhu, F | 1 |
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| Gao, W; Guo, C; Meng, B; Pu, L; Tang, Z; Wei, J | 1 |
| Dudiki, T; Ferrara, JK; Kadunganattil, S; Kline, DW; Vijayaraghavan, S | 1 |
| Deming, TJ; Gharakhanian, EG | 1 |
| Wang, L; Wang, X; Yang, Z; Zhang, W; Zhou, S | 1 |
| Blanco, R; Colombo, A; Pardo, R; Suazo, J | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y | 1 |
| Karas Kuželički, N | 1 |
| Augoustides-Savvopoulou, P; Barić, I; Blom, HJ; Chien, YH; Dobbelaere, D; Grünert, SC; Opladen, T; Petković Ramadža, D; Rakić, B; Staufner, C; Wedell, A | 1 |
| Bandeira, A; Baumgartner, MR; Benoist, JF; Blom, H; Burlina, A; Cerone, R; Couce, ML; Diodato, D; Dionisi-Vici, C; Garcia-Cazorla, A; Huemer, M; Kožich, V; la Marca, G; Pasquini, E; Schiff, M; Schwahn, B; Vilarinho, L; Weisfeld-Adams, JD | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Couce, ML; Llarena, M; López-Suárez, O | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Feng, J; Tang, H; Wang, N; Wang, W; Wang, X | 1 |
| Koloshko, O; Korda, М; Melnyk, A; Nechiporuk, V; Zaichko, N | 1 |
| Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF | 1 |
| Ahmed, A; Ahsan, H; Finnell, RH; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Kibriya, MG; Levy, D; Liu, X; Navas-Acien, A; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V; Zhu, H | 1 |
| Awwad, HM; Eskelund, AR; Geisel, J; Obeid, R; Tillmann, S; Treccani, G; Wegener, G | 1 |
| Borowczyk, K; Jakubowski, H; Suliburska, J | 1 |
| Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T | 1 |
| Fry, RC; Gamble, MV; Garcia-Vargas, G; Herring, AH; Ilievski, V; Laine, JE; Richardson, DB; Rubio-Andrade, M; Stýblo, M | 1 |
| Chakraborty, A; Chang, CC; Chang, YS; Chen, TW; Chen, YT; Cheng, ML; Chien, KY; Hsieh, YJ; Huang, SC; Lee, YH; Lin, TY; Lin, WC; Lin, YT; Liu, JL; Luo, JD; Pai, LM; Shiao, MS; Sung, LY; Tang, HY; Tung, CS; Wang, PY; Yeh, CT; Yu, JS | 1 |
| Chiang, AJ; Gugiu, GB; Hu, W; Kalkum, M; Morra, CN; Röth, D; Versalovic, J | 1 |
| Drozdov, VN; Kruchinina, TV; Makhova, AA; Shikh, EV | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R | 1 |
| Belardo, A; Gevi, F; Zolla, L | 1 |
| Jadavji, NM; Murray, LK | 1 |
| Choi, ET; Cueto, R; Fang, P; Fu, H; Gao, C; Liu, L; Shao, Y; Shen, W; Wang, H; Wu, Q; Yang, WY; Yang, X | 1 |
| Adrian, L; Deobald, D; Hanna, R; Layer, G; Shahryari, S | 1 |
| Bulko, I; Dmytrenko, I; Korda, M; Nechyporuk, V; Pentiuk, L | 1 |
| Chen, X; Huang, X; Li, D; Ren, B; Shi, F; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q; Zheng, C | 1 |
| Asamoah, A; De Biase, I; Gherasim, C; La'ulu, SL; Longo, N; Yuzyuk, T | 1 |
| Chen, J; Chen, Y; Fan, S; Huang, B; Huang, Z; Liu, J; Shan, Z; Wei, X; Xie, Z; Zhang, X; Zhao, F; Zheng, Z | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
| Kožich, V; Stabler, S | 1 |
| Elango, R | 1 |
| Bouvier, D; Brailova, M; Minet-Quinard, R; Regnier, A; Sapin, V; Szymanowski, M | 1 |
| Brzezinski, K | 1 |
| Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M | 1 |
| Lin, B; Liu, Q; Tao, Y | 1 |
| Broz, P; Racek, J; Rajdl, D; Stehlík, P; Trefil, L | 1 |
| Bommarito, P; Clark, J; Fry, RC; Gamble, MV; García-Vargas, GG; Rubio-Andrade, M; Stýblo, M | 1 |
86 review(s) available for isomethyleugenol and homocysteine
| Article | Year |
|---|---|
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
Diseases of sulphur metabolism: implications for the methionine-homocysteine cycle, and vitamin responsiveness.
Topics: Adolescent; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Metabolism, Inborn Errors; Methionine; Methylation; Pyridoxine; Sulfur | 1979 |
Methylation & schizophrenia.
Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihydroxyphenylalanine; Drug Tolerance; Hallucinogens; Homocysteine; Humans; Indoles; Methionine; Methylation; Mice; Schizophrenia; Serine; Taurine | 1975 |
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine | 1992 |
DNA hypomethylation and differentiation of Friend erythroleukemia cells.
Topics: 5-Methylcytosine; Acetamides; Cell Differentiation; Cell Line; Cytosine; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Homocysteine; Leukemia, Erythroblastic, Acute; Methylation | 1988 |
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
Methionine metabolism in mammals: the biochemical basis for homocystinuria.
Topics: Alcohol Oxidoreductases; Cell-Free System; Cystathionine; Fibroblasts; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Liver; Methionine; Methylation; Methyltransferases; Protein Biosynthesis; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 1974 |
Formation, functions and regulatory importance of S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Alkanes; Alkenes; Alkynes; Amino Acids; Animals; Antineoplastic Agents; Binding Sites; Carbon Isotopes; Carboxylic Acids; Cyclopentanes; Escherichia coli; Homocysteine; Homoserine; Kinetics; Liver; Methionine; Methylation; Mice; Neoplasms, Experimental; Rats; Spleen; Transferases; Tritium; Yeasts | 1970 |
S-amino acid metabolism and its regulation in Escherichia coli and Salmonella typhimurium.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Cysteine; Escherichia coli; Feedback; Genes; Genes, Regulator; Homocysteine; Methionine; Methylation; Salmonella; Salmonella typhimurium; Serine; Sulfates; Transduction, Genetic | 1971 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
The possible role of protein-carboxyl methylation in sperm motility and capacitation.
Topics: Adenine; Adenosine; Animals; Dyneins; Homocysteine; Humans; Infertility, Male; Male; Methylation; Mitochondria; Protein Methyltransferases; Protein O-Methyltransferase; Sperm Capacitation; Sperm Motility; Spermatogenesis; Spermatozoa; Testis | 1982 |
Betaine, metabolic by-product or vital methylating agent?
Topics: Alcohol Oxidoreductases; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Diet; Ethanol; Homocysteine; Humans; Liver; Methionine; Methotrexate; Methylation; Methyltransferases; Oxidation-Reduction; Rats; Tetrahydrofolates | 1983 |
Is an elevated circulating maternal homocysteine concentration a risk factor for neural tube defects?
Topics: Biomarkers; Female; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pregnancy; Risk Factors | 1995 |
Hyperhomocysteinaemia: a role in the accelerated atherogenesis of chronic renal failure?
Topics: Adult; Age Factors; Arteriosclerosis; Cystathionine beta-Synthase; Cysteine; Female; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Humans; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Sex Factors | 1995 |
Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Blood Coagulation Factors; Blood Platelets; Child; Cystathionine beta-Synthase; Endothelium, Vascular; Fibrinolytic Agents; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Penicillamine; Risk Factors; Thrombosis; Vascular Diseases; Vitamin B 12; Vitamin B 6 Deficiency; Vitamins | 1993 |
Membrane protein damage and methylation reactions in chronic renal failure.
Topics: Homocysteine; Humans; Kidney Failure, Chronic; Membrane Proteins; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; S-Adenosylhomocysteine; Substrate Specificity | 1996 |
Folate, vitamin B12, and neuropsychiatric disorders.
Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Role of homocysteine in age-related vascular and non-vascular diseases.
Topics: Aged; Aging; Alcoholism; Central Nervous System; Cerebrovascular Disorders; Cognition; Coronary Disease; Depression; Estrogens; Female; Folic Acid Deficiency; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Peripheral Vascular Diseases; Renal Replacement Therapy; Vascular Diseases; Vitamin B 12 Deficiency | 1997 |
Adverse effects of hyperhomocysteinemia and their management by folic acid.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Methylation; Risk Factors; Uremia | 1997 |
[Folates and the neural tube. Review of the literature].
Topics: Animals; Europe; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methionine; Methylation; Neural Crest; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care; Prevalence; Risk Factors | 1997 |
The metabolism of homocysteine: pathways and regulation.
Topics: Animals; Homocysteine; Humans; Hydrolysis; Methionine; Methylation; S-Adenosylmethionine | 1998 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Neural tube defects, vitamins and homocysteine.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Rats; Spinal Dysraphism | 1998 |
Enzyme-catalyzed methyl transfers to thiols: the role of zinc.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Archaea; Catalysis; Dimethylallyltranstransferase; Homocysteine; Methylation; Sulfhydryl Compounds; Vitamin B 12; Zinc | 1997 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
Folate and oral clefts: where do we go from here? New directions in oral clefts research.
Topics: Cleft Lip; Cleft Palate; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Infant, Newborn; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 1999 |
Homocysteine and ischaemic heart disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies | 1999 |
Genetic modulation of homocysteinemia.
Topics: Amino Acid Substitution; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Sulfur; Tetrahydrofolates | 2000 |
Homocysteine and transmethylations in uremia.
Topics: Acylation; Amino Acids; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Nitroso Compounds; Oxidation-Reduction; Proteins; Uremia | 2001 |
Homocysteine metabolism in renal failure.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases | 2001 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly.
Topics: Aged; Biomarkers; Folic Acid Deficiency; Geriatric Assessment; Homocysteine; Humans; Mental Disorders; Methylation; Neuropsychological Tests; Severity of Illness Index; Vitamin B 12 Deficiency | 2001 |
The importance of hyperhomocysteinemia as a risk factor for diseases: an overview.
Topics: Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Methylation; Models, Biological; Models, Chemical; Pregnancy; Risk Factors; Vascular Diseases; Vitamin B 12 Deficiency | 2001 |
Beneficial role for folate in the prevention of colorectal and breast cancer.
Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Methylation; Prospective Studies; Risk Factors | 2001 |
Methods for measuring sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Methionine; Methylation; Models, Biological; Radioisotope Dilution Technique; Vitamin B 12 | 2002 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Genetics of hyperhomocysteinaemia in cardiovascular disease.
Topics: Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Polymorphism, Genetic | 2003 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism.
Topics: Biomarkers; Carbon; Diet; DNA Methylation; Folic Acid; Homocysteine; Humans; Methylation; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2003 |
News and views on folate and elderly persons.
Topics: Aged; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mental Disorders; Methylation; Neoplasms; Risk Factors; Vitamin B 12 Deficiency | 2003 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Methylation demand: a key determinant of homocysteine metabolism.
Topics: Animals; Creatine; Guanidinoacetate N-Methyltransferase; Homocysteine; Humans; Levodopa; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats | 2004 |
Homocysteine remethylation and trans-sulfuration.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Sulfur | 2004 |
Methylation demand and homocysteine metabolism.
Topics: Animals; Homocysteine; Humans; Levodopa; Methionine Adenosyltransferase; Methylation; Methyltransferases; Niacin; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2004 |
Folate metabolism and cardiovascular disease.
Topics: Biomarkers; Cardiovascular Diseases; DNA; Folic Acid; Homocysteine; Humans; Methylation; Risk Factors | 2005 |
Genetic determinants of plasma total homocysteine.
Topics: Cardiovascular Diseases; Genetic Markers; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors | 2005 |
Homocysteine and methionine metabolism in renal failure.
Topics: Biomarkers; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Failure, Chronic; Methionine; Methylation | 2005 |
Homocysteine and folate metabolism in depression.
Topics: Animals; Depression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Neurotransmitter Agents; Vitamin B 12 Deficiency | 2005 |
Hyperhomocysteinemia and macromolecule modifications in uremic patients.
Topics: Animals; DNA; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Uremia | 2005 |
Hyperhomocysteinemia and response of methionine cycle intermediates to vitamin treatment in renal patients.
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Methionine; Methylation; Vitamins | 2005 |
The use of betaine in the treatment of elevated homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation | 2006 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
[Molecular mechanisms of biotoxicity of homocysteine--facts and hypotheses].
Topics: Animals; Arginine; Atherosclerosis; Homocysteine; Humans; Hydrolysis; Methylation; Nitric Oxide; Oxidative Stress | 2005 |
The nutritional relationship linking sulfur to nitrogen in living organisms.
Topics: Aging; Animals; Body Composition; Diet; Homeostasis; Homocysteine; Humans; Methionine; Methylation; Nitrates; Nitrogen; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Prealbumin; Protein Deficiency; Stress, Physiological; Sulfates; Sulfur | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Neural tube defects and folate: case far from closed.
Topics: Animals; Central Nervous System; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects | 2006 |
Phosphatidylethanolamine N-methyltransferase and regulation of homocysteine.
Topics: Homocysteine; Humans; Methylation; Phosphatidylethanolamine N-Methyltransferase | 2006 |
S-adenosylmethionine and its products.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glycine N-Methyltransferase; Homocysteine; Humans; Liver; Methionine Adenosyltransferase; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Mechanisms of homocysteine-induced glomerular injury and sclerosis.
Topics: Animals; Endoplasmic Reticulum; Homocysteine; Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Kidney Glomerulus; Methylation; Mitochondria; Models, Biological; Oxidative Stress; Oxygen; Reactive Oxygen Species; Sclerosis | 2008 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Folic acid, methylation and neural tube closure in humans.
Topics: Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Metabolic Networks and Pathways; Methylation; Methyltransferases; Models, Biological; Neural Tube; Neural Tube Defects; Pregnancy | 2009 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
[The role of methylation processes in etiology and pathogenesis of schizophrenia].
Topics: DNA; Genetic Predisposition to Disease; Homocysteine; Humans; Methylation; Receptors, Dopamine; Schizophrenia | 2009 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
Hypohomocysteinemia: a potentially treatable cause of peripheral neuropathology?
Topics: Aged; Female; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Peripheral Nervous System Diseases | 2012 |
Effects of decreased availability of sulfur amino acids in severe childhood undernutrition.
Topics: Amino Acids, Sulfur; Biological Availability; Child; Child Nutrition Disorders; Child, Preschool; Edema; Glutathione; Homocysteine; Humans; Methionine; Methylation; Protein-Energy Malnutrition | 2012 |
Homocysteine imbalance: a pathological metabolic marker.
Topics: Biomarkers; Epigenesis, Genetic; Health; Homocysteine; Humans; Hyperhomocysteinemia; Methylation | 2012 |
The role of B vitamins in preventing and treating cognitive impairment and decline.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Role of heat-shock proteins and cobalamine in maintaining methionine synthase activity.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Heat-Shock Proteins; Homocysteine; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; Plaque, Atherosclerotic; Vitamin B 12 | 2012 |
Defective homocysteine metabolism: potential implications for skeletal muscle malfunction.
Topics: Endoplasmic Reticulum Stress; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Muscle, Skeletal; Nitric Oxide; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Signal Transduction | 2013 |
Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology.
Topics: Cardiovascular Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Oxidation-Reduction; Randomized Controlled Trials as Topic; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 2013 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
Methylation reactions, the redox balance and atherothrombosis: the search for a link with hydrogen sulfide.
Topics: Animals; Aspirin; Atherosclerosis; Folic Acid; Gasotransmitters; Homocysteine; Humans; Hydrogen Sulfide; Methionine; Methylation; Oxidation-Reduction; Thrombosis | 2015 |
Homocysteine in Chronic Kidney Disease.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Oxidation-Reduction; Oxidative Stress | 2015 |
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis.
Topics: Biomarkers; Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Vitamin B 12 | 2016 |
S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders.
Topics: Animals; Depression; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Mental Disorders; Methylation; S-Adenosylmethionine; Time Factors | 2016 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency.
Topics: Animals; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Proto-Oncogene Proteins c-cbl; Vitamin B 12 | 2017 |
[S-methylmethionin (vitamin U): experimental studies and clinical perspective].
Topics: Adipocytes; Animals; Antioxidants; Gastrointestinal Agents; Homocysteine; Humans; Methylation; Vitamin U | 2018 |
The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms.
Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex | 2019 |
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Amino Acid Motifs; Animals; Crystallography, X-Ray; Databases, Protein; Homocysteine; Humans; Ligands; Methylation; Molecular Conformation; NAD; Nucleotides; Protein Binding; Protein Domains; Protein Folding; Software | 2020 |
Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?
Topics: Aged; Animals; Creatine; Dietary Supplements; Energy Metabolism; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Risk Assessment | 2021 |
17 trial(s) available for isomethyleugenol and homocysteine
| Article | Year |
|---|---|
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Deficiencies of folate and vitamin B(6) exert distinct effects on homocysteine, serine, and methionine kinetics.
Topics: Adult; Amino Acids; Diet; Folic Acid Deficiency; Homocysteine; Humans; Leucine; Male; Methionine; Methylation; Nutritional Physiological Phenomena; Nutritional Status; Polymorphism, Genetic; Serine; Vitamin B 6 Deficiency | 2001 |
Randomized trial of methylcobalamin and folate effects on homocysteine in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2002 |
Regulation of sulfur amino acid metabolism in men in response to changes in sulfur amino acid intakes.
Topics: Adult; Amino Acids, Sulfur; Carbon Isotopes; Cross-Over Studies; Cysteine; Deuterium; Diet; Dietary Proteins; Homocysteine; Humans; Kinetics; Male; Methionine; Methylation; Nutritional Requirements | 2003 |
Can black tea influence plasma total homocysteine concentrations?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cholesterol; Cross-Over Studies; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Lipids; Male; Methylation; Middle Aged; Phenols; Polymers; Polyphenols; Tea; Vitamin B 12; Vitamin B 6 | 2003 |
Oral estradiol decreases plasma homocysteine, vitamin B6, and albumin in postmenopausal women but does not change the whole-body homocysteine remethylation and transmethylation flux.
Topics: Aged; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylation; Middle Aged; Postmenopause; Serum Albumin; Vitamin B 6 | 2005 |
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.
Topics: Adult; Analysis of Variance; Animals; Choline; Choline Deficiency; Cross-Over Studies; Homocysteine; Humans; Lipotropic Agents; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Middle Aged; Nutritional Status; Pilot Projects | 2005 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine.
Topics: Animals; Betaine; Chickens; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Creatine; Creatinine; Dietary Supplements; Double-Blind Method; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Skin Neoplasms; Urinary Bladder Neoplasms; Vitamin B Complex; Water Pollutants, Chemical | 2006 |
Folic acid supplementation lowers blood arsenic.
Topics: Arsenic; Arsenicals; Bangladesh; Dietary Supplements; Double-Blind Method; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
A proteomics study reveals a predominant change in MaoB expression in platelets of healthy volunteers after high protein meat diet: relationship to the methylation cycle.
Topics: Adult; Blood Platelets; Cognition; Electrophoresis, Gel, Two-Dimensional; Fasting; Food, Fortified; Homocysteine; Humans; Male; Methylation; Monoamine Oxidase; Neuropsychological Tests; Proteins; Proteomics; Psychomotor Performance; Reaction Time; Single-Blind Method; Statistics as Topic; Statistics, Nonparametric; Up-Regulation; Vitamin B 12; Young Adult | 2011 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
358 other study(ies) available for isomethyleugenol and homocysteine
| Article | Year |
|---|---|
Giant heterogeneous polyadenylic acid on vesicular stomatitis virus mRNA synthesized in vitro in the presence of S-adenosylhomocysteine.
Topics: Cell-Free System; Homocysteine; Methylation; Poly A; RNA-Dependent RNA Polymerase; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; Transcription, Genetic; Vesicular stomatitis Indiana virus | 1977 |
Inhibition of viral RNA methylation in herpes simplex virus type 1-infected cells by 5' S-isobutyl-adenosine.
Topics: Cell Line; Homocysteine; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; Simplexvirus; Viral Proteins; Virus Replication | 1977 |
Decreased rate of S-adenosyl-L-homocysteine metabolism: an early event related to transformation in cells infected with Rous sarcoma virus.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Oxidoreductases; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Homocysteine; Hydrolases; Methylation; Neoplasm Proteins; Proteins; S-Adenosylhomocysteine; Tumor Virus Infections | 1977 |
S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Division; Cell Line; Homocysteine; Humans; Lactones; Lymphocytes; Methylation; Phosphotransferases; S-Adenosylhomocysteine | 1979 |
"Pretranscriptional capping" in the biosynthesis of cytoplasmic polyhedrosis virus mRNA.
Topics: Adenylyl Imidodiphosphate; Base Sequence; Guanine Nucleotides; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic | 1978 |
S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Stimulation, Chemical | 1978 |
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
[Methyls of biological importance].
Topics: Betaine; Carnitine; Choline; Dealkylation; Homocysteine; Humans; Lipid Metabolism; Methane; Methionine; Methylation; Phosphatidylcholines | 1979 |
Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on catecholamine methylation in neuroblastoma cells.
Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cells, Cultured; Dopamine; Homocysteine; Methylation; Mice; Neuroblastoma; S-Adenosylhomocysteine | 1977 |
Activities of some enzymes involved in homocysteine methylation in brain, liver and kidney of the developing rhesus monkey.
Topics: Age Factors; Animals; Brain; Haplorhini; Homocysteine; Kidney; Liver; Macaca mulatta; Methylation; Methyltransferases | 1976 |
The effect of S-adenosylhomocysteine on DNA methylation in isolated rat liver nuclei.
Topics: Animals; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Homocysteine; Liver; Liver Regeneration; Male; Methylation; Rats; S-Adenosylhomocysteine | 1977 |
Tetrahydrofolic acid: an inhibitor of the methyltetrahydrofolic acid-mediated methylation of indolethylamines.
Topics: Adenosine; Animals; Binding, Competitive; Bufotenin; Ethylamines; Homocysteine; Indoles; Lung; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Serotonin; Tetrahydrofolates | 1975 |
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1975 |
The effect of intrinsic factor proteins on the methylating activity of CH3-B12 coenzyme.
Topics: Animals; Cobamides; Homocysteine; Intrinsic Factor; Methionine; Methylation | 1975 |
Formation of methyl mercury by bacteria.
Topics: Bacillus; Bacteria; Enterobacter; Escherichia; Homocysteine; Mercury; Methylation; Oxygen; R Factors; Soil Microbiology; Staphylococcus; Stereoisomerism; Streptococcus; Vitamin B 12; Water Microbiology | 1975 |
Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on transfer ribonucleic acid methylation in phytohemagglutinin-stimulated lymphocytes.
Topics: Animals; DNA; Homocysteine; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methylation; Rats; Rats, Inbred Strains; RNA, Transfer; S-Adenosylhomocysteine; Tubercidin | 1975 |
Analogues of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis of analogues with modifications at the 5'-thioether linkage.
Topics: Alkylation; Catechol O-Methyltransferase Inhibitors; Homocysteine; Methylation; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1976 |
Histamine H2-receptor in atrium: signal transduction and response.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Homocysteine; Methylation; Myocardium; Phospholipids; Receptors, Histamine H2; Signal Transduction; Stimulation, Chemical | 1991 |
Inhibitors of membrane lipid metabolism enhance complement-mediated nucleated cell killing through distinct mechanisms.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Complement C9; Complement Membrane Attack Complex; Complement System Proteins; Cytotoxicity, Immunologic; Flow Cytometry; Homocysteine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Membrane Lipids; Methylation; Mice; Thimerosal | 1991 |
Inhibitors of membrane transmethylation reactions prevent the lymphocyte chemokinetic response.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Bradykinin; Chemotaxis, Leukocyte; Colchicine; Homocysteine; Humans; Interleukin-16; Leukocytes, Mononuclear; Lymphocytes; Lymphokines; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Second Messenger Systems | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
Transmethylation of homocysteine to methionine: efficiency in the rat and chick.
Topics: Animals; Betaine; Body Weight; Chickens; Choline; Diet; Homocysteine; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Sarcosine; Tetrahydrofolates | 1985 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
Blockade by methylation inhibitors of the anaphylactic response of guinea-pig lung strips.
Topics: Adenosine; Airway Resistance; Anaphylaxis; Animals; Female; Guinea Pigs; Histamine Release; Homocysteine; In Vitro Techniques; Lung; Male; Methylation; Ovalbumin; Thromboxane B2; Tubercidin | 1987 |
IgE-dependent activation of human lung mast cells is not associated with increased phospholipid methylation.
Topics: Antibodies, Anti-Idiotypic; Calcimycin; Cyclic AMP; Histamine Release; Homocysteine; Humans; Immunoglobulin E; Lung; Mast Cells; Methylation; Phospholipids; Tubercidin | 1988 |
Spontaneous and 5-azacytidine-induced revertants of methionine-dependent tumor-derived and H-ras-1-transformed cells.
Topics: Animals; Azacitidine; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Culture Media; Ethyl Methanesulfonate; Homocysteine; Methionine; Methylation; Oncogenes; Tumor Cells, Cultured | 1989 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.
Topics: Animals; Diethylnitrosamine; Genes, ras; Homocysteine; Immunoblotting; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Regulation of S-adenosyl methionine synthesis in the mouse embryo.
Topics: Animals; Binding, Competitive; Blastocyst; Embryo, Mammalian; Ethionine; Homocysteine; Humans; Methionine; Methylation; Mice; Mice, Inbred Strains; Morula; Oocytes; S-Adenosylmethionine | 1989 |
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.
Topics: Animals; Apolipoproteins; Betaine; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Deanol; Ethanolamine; Ethanolamines; Homocysteine; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Triglycerides | 1989 |
Relationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Cell Division; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; L Cells; Methylation; Mice; S-Adenosylhomocysteine; Time Factors; Vaccinia virus; Virus Replication | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
Topics: Aminopyridines; Animals; Carcinogens; Deoxycytidine; DNA; Homocysteine; Liver; Male; Methapyrilene; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Regulation of mononuclear leukocyte function by transmethylation reactions.
Topics: Animals; Cell Migration Inhibition; Enzyme Activation; Guinea Pigs; Homocysteine; Macrophages; Methylation; Oxygen; Phospholipases; S-Adenosylmethionine; Superoxides | 1985 |
Effects of S-adenosylhomocysteine and analogs on Epstein-Barr virus-induced transformation, expression of the Epstein-Barr virus capsid antigen, and methylation of Epstein-Barr virus DNA.
Topics: Capsid; Cell Line; Cell Transformation, Viral; DNA, Viral; Herpesvirus 4, Human; Homocysteine; Humans; Lymphocytes; Methylation; S-Adenosylhomocysteine; Structure-Activity Relationship | 1987 |
Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro.
Topics: Animals; Bucladesine; Cell Membrane; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Homocysteine; Leydig Cells; Luteinizing Hormone; Male; Methylation; Rats; Receptors, LH; S-Adenosylhomocysteine; S-Adenosylmethionine; Testosterone | 1987 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
The transmethylation pathway as a source for adenosine in the isolated guinea-pig heart.
Topics: Adenosine; Animals; Guinea Pigs; Homocysteine; In Vitro Techniques; Methylation; Myocardium; Oxygen; Perfusion; S-Adenosylhomocysteine | 1988 |
General characteristics of the superprecipitation reaction of rat crude uterine myosin B: effects of L-methionine and/or transmethylation blockers on the reaction.
Topics: Animals; Chemical Precipitation; Chickens; Electrophoresis, Polyacrylamide Gel; Female; Homocysteine; Methionine; Methylation; Myosins; Rats; Rats, Inbred Strains; Tubercidin; Uterus | 1987 |
Phospholipid methylation in starfish spermatozoa is linked to sperm chemoattraction.
Topics: Animals; Chemotaxis; Female; Homocysteine; Male; Membrane Lipids; Methylation; Methyltransferases; Ovum; Phospholipids; Sperm-Ovum Interactions; Spermatozoa; Starfish; Tubercidin | 1986 |
Effect of S-adenosylhomocysteine on insulin-independent release of pyruvate dehydrogenase activator from rat adipocyte plasma membranes.
Topics: Adipose Tissue; Animals; Cell Membrane; Homocysteine; In Vitro Techniques; Insulin; Male; Methylation; Phospholipids; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1987 |
L-methionine enhances the contractile responses of rat uterine smooth muscle to acetylcholine and high KCl.
Topics: Acetylcholine; Animals; Calcium Chloride; Female; Homocysteine; In Vitro Techniques; Methionine; Methylation; Phospholipids; Potassium Chloride; Proteins; Rats; Rats, Inbred Strains; Tubercidin; Uterine Contraction | 1986 |
Carboxyl methylation of human erythrocyte band 3 in intact cells. Relation to anion transport activity.
Topics: Adenosine; Anion Exchange Protein 1, Erythrocyte; Anions; Biological Transport; Cycloleucine; Erythrocytes; Homocysteine; Humans; Methylation; Phosphates | 1986 |
Inhibition of macrophage phagocytosis by methylation inhibitors. Lack of correlation of protein carboxymethylation and phospholipid methylation with phagocytosis.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Deoxyadenosines; Homocysteine; Kinetics; Macrophages; Methylation; Mice; Phagocytosis; Phospholipids; Proteins; Vidarabine | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Differential regulation of polyamine synthesis and transmethylation reactions in methylthioadenosine phosphorylase deficient mammalian cells.
Topics: Adenosine; Animals; B-Lymphocytes; Cell Division; Cell Line; Deoxyadenosines; Fibroblasts; Homocysteine; Humans; Kinetics; Methylation; Mice; Pentosyltransferases; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; T-Lymphocytes; Thionucleosides | 1985 |
Inhibitory effect of 3-deazaadenosine on the thromboplastin response of stimulated human monocytes.
Topics: Dose-Response Relationship, Drug; Homocysteine; Humans; In Vitro Techniques; Methylation; Monocytes; Phytohemagglutinins; Ribonucleosides; Thromboplastin; Tubercidin | 1985 |
Inhibition of protein carboxylmethylation and dopamine autoreceptor functioning.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Homocysteine; Male; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sulpiride; Synaptosomes | 1985 |
Transient methylation of dolichyl oligosaccharides is an obligatory step in halobacterial sulfated glycoprotein biosynthesis.
Topics: 3-O-Methylglucose; Adenosine; Bacterial Proteins; Clusterin; Glycoproteins; Halobacterium; Homocysteine; Methylation; Methylglucosides; Molecular Chaperones; Polyisoprenyl Phosphate Oligosaccharides; Polyisoprenyl Phosphate Sugars | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
An early effect of the S component of staphylococcal leukocidin on methylation of phospholipid in various leukocytes.
Topics: Adenine; Adenosine; Animals; Cell Survival; Enzyme Activation; Homocysteine; Leukocidins; Membrane Lipids; Methylation; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Rabbits; Staphylococcus | 1985 |
The role of S-adenosylhomocysteine in the biological utilization of S-adenosylmethionine.
Topics: Alcaligenes; Animals; Dictyostelium; Homocysteine; Humans; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene. II. Identity of synthetic 3-(homocystein-S-yl)-N-methyl-4-aminoazobenzene with the major polar dye P2b.
Topics: Animals; Azo Compounds; Carcinogens; Cellulose; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, Thin Layer; Coloring Agents; Elements; Homocysteine; Indicators and Reagents; Infrared Rays; Iodine; Liver; Magnetic Resonance Spectroscopy; Male; Methylation; Oxidation-Reduction; Rats; Silicon Dioxide; Spectrophotometry | 1968 |
Effect of ketone bodies and ACTH on the transmethylation reaction (S-adenosyl methionine independent system) in rats. I.
Topics: Acetoacetates; Adrenocorticotropic Hormone; Animals; Betaine; Depression, Chemical; Drug Synergism; Homocysteine; Hydroxybutyrates; In Vitro Techniques; Male; Methylation; Rats; Transferases; Vitamin B 12 Deficiency | 1969 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |
Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.
Topics: Acridines; Adenine; Adenosine; Animals; Arginine; Azo Compounds; Carbon Radioisotopes; Carcinogens; Cytoplasm; Dimethylformamide; Ethidium; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Male; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.
Topics: Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; DNA-Directed RNA Polymerases; Homocysteine; Methylation; Phosphorus Radioisotopes; Ribonucleotides; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Tritium; Uracil Nucleotides; Vesicular stomatitis Indiana virus; Viral Proteins | 1974 |
N-5,10-methylenetetrahydrofolate reductase deficiency and schizophrenia: a working hypothesis.
Topics: Adolescent; Dopamine; Female; Fibroblasts; Folic Acid; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Oxidoreductases; Schizophrenia; Tetrahydrofolates | 1974 |
Actions of serotonin and related substances on single neurons in the brain.
Topics: Acetylcholine; Action Potentials; Aminobutyrates; Animals; Behavior; Brain; Brain Stem; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Hallucinogens; Homocysteine; Iontophoresis; Lysergic Acid Diethylamide; Methylation; Methysergide; N,N-Dimethyltryptamine; Neurons; Norepinephrine; Rats; Serotonin; Serotonin Antagonists; Tryptamines | 1974 |
Transductional analysis of methionine genes in Proteus mirabilis.
Topics: Aminocaproates; Drug Resistance, Microbial; Ethionine; Genes; Genes, Regulator; Genetic Linkage; Homocysteine; Methionine; Methylation; Mutation; Phenotype; Proteus; Proteus mirabilis; Transduction, Genetic | 1972 |
[Regulatory aspects in methionine biosynthesis].
Topics: Escherichia coli; Homocysteine; Methionine; Methylation | 1972 |
Methionine and vitamin B 12 repression and precursor induction in the regulation of homocysteine methylation in Salmonella typhimurium.
Topics: Apoproteins; Chloramphenicol; Enzyme Induction; Enzyme Precursors; Genes, Regulator; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Oxidoreductases; Salmonella typhimurium; Tetrahydrofolates; Vitamin B 12 | 1973 |
Studies on synthetic inhibitors of t-RNA methyl transferases: analogs of S-adenosyl homocysteine.
Topics: Adenosine; Animals; Cysteamine; Cysteine; Escherichia coli; Homocysteine; Kinetics; Liver; Methylation; Propionates; Propylene Glycols; Rabbits; RNA, Transfer; tRNA Methyltransferases | 1973 |
S-adenosylmethionine metabolism by members of the genus Candida.
Topics: Candida; Candida albicans; Carbon Radioisotopes; Cell-Free System; Chromatography; Culture Media; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1973 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
The microbial biosynthesis of methionine.
Topics: Bacillus megaterium; Basidiomycota; Candida; Carbon Isotopes; Catalase; Escherichia coli; Homocysteine; Methionine; Methylation; Methyltransferases; Serine; Tetrahydrofolate Dehydrogenase | 1972 |
Studies on S-adenosylhomocysteine inhibition of histamine transmethylation in brain.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Fluorometry; Guinea Pigs; Histamine; Homocysteine; Hot Temperature; Kinetics; Methylation; Methyltransferases; Protein Denaturation; Proteins; Pyrogallol; Time Factors; Tritium | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Histidine catabolism in iron-deficient rats.
Topics: Anemia, Hypochromic; Animals; Blood Proteins; FIGLU Test; Hemoglobins; Histidine; Homocysteine; Iron; Liver; Male; Methylation; Rats; Transferases; Vitamin B 12 | 1973 |
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
Enzymic synthesis of methionine: formation of a radioactive cobamide enzyme with N5-methyl-14C-tetrahydrofolate.
Topics: Carbon Isotopes; Catalysis; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Kinetics; Methionine; Methylation; Transferases; Vitamin B 12 | 1967 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine methyltransferase: sequential formation of bound methylcobalamin with S-adenosyl-L-methionine and N5-methyltetrahydrofolate.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Light; Methionine; Methylation; Nucleosides; Temperature; Time Factors; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: activation with S-adenosyl-L-methionine and the mechanism for methyl group transfer.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Models, Biological; Nucleosides; Time Factors; Transferases; Vitamin B 12 | 1969 |
The substrate specificity of 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase.
Topics: Escherichia coli; Folic Acid; Glutamates; Homocysteine; Methionine; Methylation; Neurospora; Saccharomyces; Transferases | 1969 |
The specificity of S-adenosylmethionine derivatives in methyl transfer reactions.
Topics: Animals; Aspergillus; Binding Sites; Brain; Butyrates; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Escherichia coli; Feedback; Guinea Pigs; Histamine; Homocysteine; Isomerases; Methionine; Methylation; Nucleosides; Saccharomyces; Serotonin; Spectrophotometry; Transferases; Ultraviolet Rays | 1969 |
New methionine structural gene in Salmonella typhimurium.
Topics: Chromosome Mapping; Genetics, Microbial; Homocysteine; Methionine; Methylation; Molecular Biology; Mutation; Salmonella typhimurium; Temperature; Transduction, Genetic | 1969 |
On the role of S-adenoxylmethionine in the vitamin B12 dependent methionine biosynthesis.
Topics: Alcohols; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxyapatites; Kinetics; Methionine; Methods; Methylation; Nucleosides; Spectrophotometry; Sulfur; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: resolution and reconstitution of holoenzyme.
Topics: Alcohols; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Darkness; Escherichia coli; Homocysteine; Light; Methionine; Methylation; Nucleosides; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Sulfur; Tetroses; Transferases; Tritium; Ultracentrifugation; Urea; Vibration; Vitamin B 12 | 1970 |
Spectrophotometric evidence for the formation of an Escherichia coli B B-12s methyltransferase.
Topics: Alcohols; Carbon Isotopes; Escherichia coli; Folic Acid; Free Radicals; Homocysteine; Hydrogen-Ion Concentration; Iodides; Ligases; Methionine; Methylation; Oxidation-Reduction; Spectrophotometry; Sulfur; Transferases; Ultraviolet Rays; Vitamin B 12 | 1970 |
Biochemical model for the biological methylation of mercury suggested from methylation studies in vivo with Neurospora crassa.
Topics: Chromatography, Gas; Culture Media; Cysteine; Homocysteine; Mercury; Methylation; Models, Chemical; Mutation; Neurospora | 1971 |
Methylation of mercury compounds by methylcobalamin.
Topics: Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gas; Escherichia coli; Homocysteine; Hydroxides; Hydroxocobalamin; Kinetics; Mercaptoethanol; Mercury; Mercury Poisoning; Methylation; Organometallic Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 1971 |
The vitamin B12-dependent methionine synthetase. The cycle of transmethylation.
Topics: Enzyme Induction; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; Nucleosides; Oxidation-Reduction; Spectrophotometry; Transferases; Vitamin B 12 | 1971 |
Methylcobalamin as a substrate at a separate site on Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase.
Topics: Alkylation; Binding Sites; Carbon Isotopes; Catalysis; Coenzymes; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Temperature; Tritium; Urea; Vitamin B 12 | 1971 |
Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.
Topics: Alkylation; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dithiothreitol; Drug Stability; Escherichia coli; Folic Acid; Homocysteine; Hydroxocobalamin; Macromolecular Substances; Mathematics; Methylation; Methyltransferases; Molecular Weight; Tritium; Urea; Vitamin B 12 | 1971 |
Transductional analysis of Pseudomonas aeruginosa methionineless auxotrophs.
Topics: Cysteine; Genetics, Microbial; Homocysteine; Methionine; Methylation; Mutation; Pseudomonas aeruginosa; Transduction, Genetic; Vitamin B 12 | 1969 |
The enzymatic synthesis of fatty acid methyl esters by carboxyl group alkylation.
Topics: Acetone; Calcium; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Enzyme Inhibitors; Enzymes; Esters; Fatty Acids; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Lipase; Methionine; Methylation; Mycobacterium; Nucleosides; Oleic Acids; Phospholipids; Solubility | 1970 |
Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis and biological activity of homocysteine derivatives bridged to adenine.
Topics: Adenine; Adenosine; Catechol O-Methyltransferase Inhibitors; Chromatography, Ion Exchange; Chromatography, Thin Layer; Homocysteine; Methylation; Spectrum Analysis; Structure-Activity Relationship; Ultraviolet Rays | 1972 |
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Carbon Isotopes; Coenzymes; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Methionine; Methylation; Methyltransferases; Oxidoreductases; Vitamin B 12 | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
Inhibition of catechol-O-methyltransferase by S-adenosylhomocysteine and S-adenosylhomocysteine sulfoxide, a potential transition-state analog.
Topics: Adenosine; Animals; Carbon Isotopes; Catechol O-Methyltransferase Inhibitors; Chemical Phenomena; Chemistry; Homocysteine; Kinetics; Liver; Methylation; Methyltransferases; Rats; Structure-Activity Relationship; Sulfoxides | 1972 |
[Dissociation behavior of cysteine and related SH-compounds. A 13 C-NMR spectroscopic study on pH dependence of charge distribution].
Topics: Amines; Butyrates; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteamine; Cysteine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Penicillamine; Propionates; Sulfhydryl Compounds; Tritium; Valine | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
Biosynthesis of dimethylarsine by Methanobacterium.
Topics: Anaerobiosis; Arsenic; Arsenicals; Autoradiography; Bacteria; Carbon Isotopes; Cells, Cultured; Chromatography, Thin Layer; Desulfovibrio; Electrophoresis; Homocysteine; Light; Methane; Methylation; Radioisotopes; Selenium; Spectrum Analysis; Tellurium; Ultraviolet Rays | 1971 |
Ethionine and methionine metabolism by the chrysomonad flagellate Prymnesium parvum.
Topics: Animals; Carbon Isotopes; Chromatography, Paper; Culture Media; Cysteine; Ethionine; Eukaryota; Homocysteine; Methionine; Methods; Methylation; Nitrogen; Oxidation-Reduction; Sulfones; Sulfoxides; Time Factors | 1971 |
Participation of pangamic acid (vitamin B 15 ) in synthesis of methyl group of methionine and biosynthesis of corrinoids.
Topics: Animals; Culture Media; Homocysteine; Liver; Methionine; Methylation; Propionibacterium; Rats; Vitamin B Complex | 1971 |
The action of adenosine thioethers, and its analytical application. ANL-7535.
Topics: Aminohydrolases; Ethers; Homocysteine; Methionine; Methylation; Spectrophotometry; Transferases | 1968 |
Defective metabolism of vitamin B 12 in fibroblasts from children with methylmalonicaciduria.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cobalt Isotopes; Deoxyadenosines; Enzyme Activation; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Malonates; Metabolism, Inborn Errors; Methylation; Methyltransferases; Vitamin B 12 | 1971 |
Influence of methionine pool composition on the formation of methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Culture Media; Homocysteine; Methionine; Methylation; Mutation; RNA, Transfer; Saccharomyces | 1969 |
Methylcobalamin as an intermediate in mammalian methionine biosynthesis.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Electrophoresis; Ethanol; Folic Acid; Homocysteine; Kidney; Methionine; Methylation; Nucleosides; Photochemistry; Solubility; Swine; Transferases; Vitamin B 12 | 1970 |
Methylation of homocysteine in Coprinus lagopus.
Topics: Basidiomycota; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Transferases | 1970 |
Hydrocarbon-utilizing microorganism. Relationship of fatty acid composition and biosynthesis to hydrocarbon substrate and to vitamin B 12 level in Corynebacterium simplex.
Topics: Alkanes; Carbon Isotopes; Cobalt; Corynebacterium; Culture Media; Fatty Acids; Folic Acid; Homocysteine; Methionine; Methylation; Nucleosides; Spectrum Analysis; Transferases; Vitamin B 12 | 1970 |
Inhibition of transmethylations of biogenic amines by S-adenosylhomocysteine. Enhancement of transmethylation by adenosylhomocysteinase.
Topics: Adrenal Glands; Animals; Brain; Carbon Isotopes; Catechols; Epinephrine; Homocysteine; Hydrolases; Indoles; Methylation; Methyltransferases; Nucleosides; Rabbits; Rats; S-Adenosylmethionine | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
[The role of vitamin B12 in metabolism].
Topics: Animals; Coenzymes; Folic Acid; Homocysteine; Humans; Isomerases; Methylation; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Ethionine and methionine biosynthesis in rat liver.
Topics: Animals; Betaine; Ethionine; Homocysteine; Liver; Male; Methionine; Methylation; Rats; Stereoisomerism; Stimulation, Chemical; Transferases | 1969 |
Serine transhydroxymethylase in methionine biosynthesis in Saccharomyces cerevisiae.
Topics: Cell-Free System; Enzyme Repression; Glycine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Methylation; Saccharomyces; Serine; Transferases | 1969 |
3-Deazaadenosine and L-homocysteine inhibit human platelet activation induced by arachidonic acid, U46619 and phospholipase C.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Homocysteine; Humans; Isomerism; Methylation; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Ribonucleosides; Thrombin; Tubercidin; Type C Phospholipases | 1984 |
Labile methyl group balances in the human: the role of sarcosine.
Topics: Adolescent; Child; Choline; Cystine; Diet; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Nitrogen; Phosphatidylcholines; Sarcosine | 1980 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA.
Topics: Chromatography, High Pressure Liquid; HeLa Cells; Homocysteine; Humans; Interferons; Methylation; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1983 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin | 1983 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Methotrexate hepatotoxicity.
Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides | 1984 |
Effect of undermethylation on mRNA cytoplasmic appearance and half-life.
Topics: Chromatography, High Pressure Liquid; Half-Life; HeLa Cells; Homocysteine; Humans; Kinetics; Methylation; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; S-Adenosylhomocysteine | 1984 |
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro.
Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine | 1981 |
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline | 1982 |
Potentiation of the growth inhibitory effects of adenosine 3',5'-monophosphate analogues by homocysteine.
Topics: Animals; Bucladesine; Carcinoma 256, Walker; Drug Synergism; Homocysteine; Methylation; S-Adenosylhomocysteine | 1982 |
Role of transmethylation in the elicitation of an oxidative burst in macrophages.
Topics: Adenosine; Animals; Concanavalin A; Depression, Chemical; Guinea Pigs; Homocysteine; Lectins; Macrophage Activation; Macrophages; Methylation; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tubercidin; Wheat Germ Agglutinins | 1982 |
Inhibition of rat brain microsomal Na+,K+-ATPase by S-adenosylmethionine.
Topics: Animals; Brain; Homocysteine; Lipid Metabolism; Methylation; Microsomes; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Tubercidin | 1984 |
Impairment of insulin release by methylation inhibitors.
Topics: Animals; Calcium; Homocysteine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipid Metabolism; Methylation; Oxidation-Reduction; Phosphatidylinositols; Proteins; Rats; Ribonucleosides; Tubercidin | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Correlations between phospholipid methylation and neuronal catecholamine transport.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cerebral Cortex; Cytosol; Homocysteine; Kinetics; Male; Membrane Lipids; Methylation; Norepinephrine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Evidence for direct methyl transfer in betaine: homocysteine S-methyl-transferase.
Topics: Betaine-Homocysteine S-Methyltransferase; Butyrates; Butyric Acid; Homocysteine; Humans; Kinetics; Liver; Methylation; Methyltransferases; Substrate Specificity | 1983 |
Methylation of phospholipids in microsomes of the rat aorta.
Topics: Animals; Aorta, Thoracic; Chromatography, Thin Layer; Fluorescence Polarization; Homocysteine; Male; Methylation; Microsomes; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypsin; Type C Phospholipases | 1983 |
Methylation inhibitors impair collagen-induced activation of human platelets.
Topics: Homocysteine; Humans; In Vitro Techniques; Isomerism; Methylation; Platelet Aggregation; Ribonucleosides; Tubercidin | 1983 |
Possible role of increased brain methylation in methionine sulfoximine epileptogenesis: effects of administration of adenosine and homocysteine thiolactone.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Histamine; Homocysteine; Methionine Sulfoximine; Methylation; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phospholipids; Reaction Time; Seizures | 1983 |
Dissociation between inhibition of phospholipid methylation and production of PAF-acether by rabbit platelets.
Topics: Animals; Blood Platelets; Crotalid Venoms; Homocysteine; Kinetics; Lectins, C-Type; Methylation; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Tubercidin | 1984 |
Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
Topics: Adenine; Adenosine; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Chemoreceptor Cells; Chemotaxis, Leukocyte; Homocysteine; Humans; Kinetics; Lipid Metabolism; Methylation; Monocytes | 1981 |
Dissociation of platelet activation from transmethylation of their membrane phospholipids.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Collagen; Crotalid Venoms; Homocysteine; Immunoglobulin E; Kinetics; Lectins, C-Type; Male; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Aggregation; Rats; Rats, Inbred Strains; Tubercidin | 1981 |
3 Deazaadenosine and L-homocysteine inhibit platelet aggregation induced by collagen and convulxin through a phospholipase A2 independent mechanism.
Topics: Animals; Calcimycin; Collagen; Crotalid Venoms; Homocysteine; Lectins, C-Type; Male; Methylation; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Aggregation; Rats; Ribonucleosides; Tubercidin | 1982 |
Biosynthesis of polyamines in mouse brain: effects of methionine sulfoximine and adenosylhomocysteine.
Topics: Animals; Brain; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Polyamines; Putrescine; S-Adenosylhomocysteine; Spermidine; Spermine | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
The effect of methotrexate on homocysteine methylating agents in rat liver.
Topics: Animals; Betaine; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Inbred Strains; Tetrahydrofolates; Time Factors | 1982 |
Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Lymphocytes; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1980 |
Transsulphuration and methylation of homocysteine in control and mutant human fibroblasts.
Topics: Cell Line; Cells, Cultured; Cystathionine beta-Synthase; Cysteine; Fibroblasts; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Mutation; Skin; Sulfur Radioisotopes | 1982 |
Inhibition of phospholipid methylation in isolated rat hepatocytes by analogues of adenosine and S-adenosylhomocysteine.
Topics: Adenosine; Animals; Homocysteine; In Vitro Techniques; Liver; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; S-Adenosylhomocysteine | 1982 |
Inhibition of the hamster sperm acrosome reaction by transmethylation inhibitors.
Topics: Acrosome; Animals; Cricetinae; Homocysteine; In Vitro Techniques; Male; Mesocricetus; Methylation; Ribonucleosides; Sperm Capacitation; Sperm Motility; Spermatozoa; Tubercidin | 1981 |
Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Male; Methylation; Mice; Nerve Tissue Proteins; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Stimulation of transcription by S-adenosyl-L-homocysteine and virion-encapsidated methyl donor in spring viraemia of carp virus.
Topics: Animals; Capsid; Carps; Homocysteine; Kinetics; Methylation; Rhabdoviridae; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic; Virion | 1981 |
Characterization of adenosine-induced cytostasis in melanoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Count; Cell Division; Cell Line; Guanosine; Homocysteine; Melanoma; Methylation; Mice; Neoplasms, Experimental; Pyrimidines; RNA, Neoplasm; Uridine | 1980 |
Effect of methionine deprivation on methylation and synthesis of macromolecules.
Topics: Animals; Cell Line; DNA, Neoplasm; Homocysteine; Humans; Macromolecular Substances; Methionine; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm | 1980 |
The rate of transmethylation in mouse liver as measured by trapping S-adenosylhomocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Homocysteine; Hydrolases; Liver; Methylation; Mice; S-Adenosylhomocysteine | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Homocysteine; Humans; Hydrolases; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Uremia | 1995 |
Homocysteinemia and schizophrenia as a case of methylation deficiency.
Topics: Adult; Female; Homocysteine; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1994 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
Methylation in fertilised and parthenogenetic preimplantation mouse embryos.
Topics: Animals; DNA Modification Methylases; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Genomic Imprinting; Homocysteine; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Parthenogenesis; Pregnancy; S-Adenosylmethionine | 1994 |
Adenosine and homocysteine together enhance TNF-mediated cytotoxicity but do not alter activation of nuclear factor-kappa B in L929 cells.
Topics: Adenosine; Cell Line; Cell Survival; Drug Synergism; Homocysteine; In Vitro Techniques; Methylation; NF-kappa B; Reactive Oxygen Species; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha | 1994 |
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1994 |
Effect of methionine and nitrous oxide on homocysteine export and remethylation in fibroblasts from cystathionine synthase-deficient, cb1G, and cb1E patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Biological Transport, Active; Cell Line; Culture Media; Cystathionine beta-Synthase; Fibroblasts; Homocysteine; Homocystinuria; Humans; Kinetics; Methionine; Methylation; Mutation; Nitrous Oxide | 1994 |
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
Topics: Animals; Ethionine; Folic Acid Deficiency; Homocysteine; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1994 |
Nitrous oxide degradation by cobalamin-dependent methionine synthase: characterization of the reactants and products in the inactivation reaction.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electrochemistry; Enzyme Activation; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Methionine; Methylation; Nitrous Oxide; Oxidation-Reduction; Oxygen; Spectrophotometry; Vitamin B 12 | 1994 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli.
Topics: Amino Acids; Crystallization; Escherichia coli; Fourier Analysis; Homocysteine; Hydroxymethylbilane Synthase; Kinetics; Mass Spectrometry; Methylation; Molecular Structure; Mutagenesis; Selenomethionine; Transformation, Bacterial; X-Ray Diffraction | 1993 |
Proofreading and the evolution of a methyl donor function. Cyclization of methionine to S-methyl homocysteine thiolactone by Escherichia coli methionyl-tRNA synthetase.
Topics: Acylation; Amino Acid Sequence; Amino Acids; Biological Evolution; Chromatography, Thin Layer; Cyclization; Escherichia coli; Homocysteine; Kinetics; Methionine; Methionine-tRNA Ligase; Methylation; Molecular Sequence Data; Oxidation-Reduction; RNA, Transfer, Met; Safrole; Sequence Homology, Amino Acid | 1993 |
Homocysteine-dependent demethylation of trimethylselenonium ion and selenobetaine with methionine formation.
Topics: Animals; Betaine; Binding, Competitive; Cytosol; Homocysteine; Homocysteine S-Methyltransferase; Kinetics; Liver; Male; Methionine; Methylation; Methyltransferases; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenium Compounds | 1993 |
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats.
Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar | 1995 |
Liver DNA and RNA metabolism in rats fed diets lacking methionine plus cysteine with or without restricted energy.
Topics: Animal Feed; Animals; Body Weight; Cell Nucleus; Cell Size; Cystathionine; Cysteine; Deoxyribonucleases; Diet; DNA; Eating; Energy Metabolism; Homocysteine; Liver; Male; Methionine; Methylation; Organ Size; Proteins; Rats; Rats, Wistar; Ribonucleases; RNA; Solubility | 1995 |
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate.
Topics: Case-Control Studies; Diet; Diet Surveys; Fasting; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methionine; Methylation; Middle Aged; Myocardial Infarction; Odds Ratio; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Low whole-blood S-adenosylmethionine and correlation between 5-methyltetrahydrofolate and homocysteine in coronary artery disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Cohort Studies; Coronary Disease; Erythrocytes; Female; Follow-Up Studies; Homocysteine; Humans; Isoenzymes; Lymphocytes; Male; Methionine Adenosyltransferase; Methylation; Middle Aged; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
The importance of transmethylation reactions to methionine metabolism in sheep: effects of supplementation with creatine and choline.
Topics: Animals; Choline; Creatine; Homocysteine; Methionine; Methylation; Sheep; Wool | 1996 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
5-Formyltetrahydrofolate regulates homocysteine remethylation in human neuroblastoma.
Topics: Antidotes; Gene Expression; Homocysteine; Humans; Leucovorin; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Neuroblastoma; Tumor Cells, Cultured | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.
Topics: Adenosine; Animals; Cell Differentiation; Cell-Free System; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Methionine; Methylation; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Processing, Post-Translational; Rats; S-Adenosylmethionine; Signal Transduction; Tritium | 1997 |
Homocysteine accumulation in human ovarian carcinoma ascitic/cystic fluids possibly caused by metabolic alteration of the methionine cycle in ovarian carcinoma cells.
Topics: Adult; Aged; Ascitic Fluid; Cysteine; Female; Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Middle Aged; Ovarian Neoplasms; Vitamin B 12 | 1997 |
Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Membrane; Cells, Cultured; Cysteine; DNA; Endothelium, Vascular; Flow Cytometry; G1 Phase; Guanosine Diphosphate; Guanosine Triphosphate; Homocysteine; Humans; Kinetics; Methylation; Muscle, Smooth, Vascular; Proto-Oncogene Proteins p21(ras); S-Adenosylhomocysteine; Time Factors; Umbilical Veins | 1997 |
Folate depletion induced by methotrexate affects methionine synthase activity and its susceptibility to inactivation by nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anesthetics, Inhalation; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methotrexate; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1997 |
Characterization of homocysteine metabolism in the rat kidney.
Topics: Animals; Chemical Fractionation; Cystathionine beta-Synthase; Homocysteine; Kidney Cortex; Kidney Tubules; Kidney Tubules, Proximal; Lyases; Male; Methylation; Rats; Rats, Sprague-Dawley; Serine; Sulfur | 1997 |
Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Edetic Acid; Escherichia coli; Homocysteine; Methyl Methanesulfonate; Methylation; Mutagenesis; Protein Binding; Protons; Recombinant Proteins; Spectrophotometry; Spectrum Analysis; Tetrahydrofolates; Vitamin B 12; Zinc | 1997 |
Evidence for disturbed S-adenosylmethionine : S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?
Topics: Adult; Aged; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Models, Biological; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
Methionine ligation strategy in the biomimetic synthesis of parathyroid hormones.
Topics: Amides; Chromatography, High Pressure Liquid; Esterification; Homocysteine; Mass Spectrometry; Methionine; Methylation; Parathyroid Hormone; Peptides; Protein Engineering; Protein Splicing | 1998 |
Renal uptake and excretion of homocysteine in rats with acute hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acute Disease; Animals; Hemodynamics; Homocysteine; Kidney; Male; Methylation; Rats; Rats, Sprague-Dawley | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Is the oral methionine loading test insensitive to the remethylation pathway of homocysteine?
Topics: Artifacts; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Reproducibility of Results; Risk Factors; Thrombophilia | 1999 |
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation.
Topics: Analysis of Variance; Animals; Female; Folic Acid; Gestational Age; Homocysteine; Methionine; Methylation; Rats; Rats, Wistar; Valproic Acid | 1999 |
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Folic Acid; Fruit; Homocysteine; Humans; Logistic Models; Male; Methylation; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Pyridoxine; Risk; Smoking; Vegetables; Vitamin B 12 | 1999 |
Homocysteine and methionine metabolism in ESRD: A stable isotope study.
Topics: Adult; Aged; Carbon Isotopes; Cardiovascular Diseases; Case-Control Studies; Deuterium; Female; Homocysteine; Humans; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Risk Factors | 1999 |
Regulation of homocysteine metabolism.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Homocysteine; Humans; In Vitro Techniques; Insulin; Kidney; Kidney Diseases; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; Sulfur; Tissue Distribution | 1999 |
In vitro methylation of arsenite by rabbit liver cytosol: effect of metal ions, metal chelating agents, methyltransferase inhibitors and uremic toxins.
Topics: Animals; Arsenites; Cresols; Cytosol; Edetic Acid; Enzyme Inhibitors; Homocysteine; Hypoxanthine; In Vitro Techniques; Inositol; Liver; Male; Metals, Heavy; Methylation; Oxalates; Pyrogallol; Rabbits; Radioisotopes; S-Adenosylhomocysteine; Substrate Specificity; Uremia | 1999 |
The effect of diet on plasma homocysteine concentrations in healthy male subjects.
Topics: Adult; Cross-Sectional Studies; Diet; Diet, Vegetarian; Fasting; Folic Acid; Homocysteine; Humans; Male; Meat; Methionine; Methylation; Middle Aged; Vitamin B 12 | 1999 |
The possible role of protein-carboxyl methylation in the regulation of flagellar movement of fowl spermatozoa.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Chloride; Chickens; Enzyme Inhibitors; Homocysteine; Luminescent Measurements; Male; Marine Toxins; Methylation; Oxazoles; Proteins; Semen; Sperm Motility; Sperm Tail; Tubercidin | 2000 |
Cell pairing and methylation in Tetrahymena thermophila are altered by exogenous homocysteine.
Topics: Animals; Cell Communication; Homocysteine; Methylation; Tetrahymena thermophila | 1999 |
Determination of isotopic enrichments of [1-13C]homocysteine, [1-13C]methionine and [2H3-methyl-1-13C]methionine in human plasma by gas chromatography-negative chemical ionization mass spectrometry.
Topics: Carbon Isotopes; Deuterium; Drug Stability; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Kinetics; Methionine; Methylation; Quality Control; Sensitivity and Specificity | 2000 |
Vitamin B-6 deficiency in rats reduces hepatic serine hydroxymethyltransferase and cystathionine beta-synthase activities and rates of in vivo protein turnover, homocysteine remethylation and transsulfuration.
Topics: Animals; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Diet; Glycine Hydroxymethyltransferase; Homocysteine; Liver; Male; Methylation; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Serine; Sulfurtransferases; Vitamin B 6 Deficiency | 2000 |
Sex-related differences in methionine metabolism and plasma homocysteine concentrations.
Topics: Absorptiometry, Photon; Adult; Breath Tests; Cardiovascular Diseases; Female; Homocysteine; Humans; Male; Methionine; Methylation; Premenopause; Reference Values; Sex Characteristics | 2000 |
Moderately low vitamin B12 does not compromise transmethylation in adults on a free diet: implications for assessment of vitamin B12 status.
Topics: Analysis of Variance; Creatine; Dietary Proteins; Homocysteine; Humans; Methionine; Methylation; Reference Values; Statistics as Topic; Vitamin B 12 | 2000 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.
Topics: Adult; Amino Acids; Cytosol; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Methylation; Mitochondria; Nutritional Status; Pilot Projects; Serine | 2000 |
Prebiotic methylation and the evolution of methyl transfer reactions in living cells.
Topics: Betaine; Biological Evolution; Ethanolamine; Evolution, Chemical; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Methylation; Methyltransferases; Origin of Life; Sulfonium Compounds | 2000 |
Quantitation of rate enhancements attained by the binding of cobalamin to methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Activation; Escherichia coli; Genetic Vectors; Homocysteine; Kinetics; Methylation; Mutagenesis, Insertional; Peptide Fragments; Recombinant Proteins; Substrate Specificity; Vitamin B 12 | 2001 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine | 2001 |
Methylation is involved in the Ustilago maydis mating response.
Topics: Cyclic AMP; Ethionine; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Pheromones; Plants; Reproduction; S-Adenosylmethionine; Signal Transduction; Ustilago | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine Nucleotides; Amidinotransferases; Animals; Creatine; Diet; Glycine; Hepatocytes; Homocysteine; Kidney; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Muscle, Skeletal; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley | 2001 |
The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.
Topics: Cohort Studies; Cross-Sectional Studies; Fasting; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin | 2002 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
Evidence for the involvement of tetrahydrofolate in the demethylation of nicotine by Nicotiana plumbaginifolia cell-suspension cultures.
Topics: Carbon Radioisotopes; Cells, Cultured; Cysteine; Homocysteine; Magnetic Resonance Spectroscopy; Methionine; Methylation; Models, Chemical; Nicotiana; Nicotine; Plant Extracts; Serine; Tetrahydrofolates | 2002 |
Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease.
Topics: Alzheimer Disease; Homocysteine; Humans; Methylation; Models, Biological; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Risk Factors; tau Proteins | 2002 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Topics: Animals; Cell Line; Cytoplasm; Deoxyribonucleotides; DNA; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Methylation; S-Adenosylmethionine; Tetrahydrofolates; Thymidine Monophosphate | 2002 |
Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
Topics: Cohort Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Thymidylate Synthase | 2002 |
Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Algorithms; Computational Biology; Ferredoxin-NADP Reductase; Homocysteine; Linear Models; Methylation; Polymorphism, Single Nucleotide; Risk Factors; Spinal Dysraphism | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
Plasma homocysteine is regulated by phospholipid methylation.
Topics: Animals; Hepatocytes; Homocysteine; Liver Neoplasms, Experimental; Male; Methylation; Methyltransferases; Mice; Mice, Knockout; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Rats, Mutant Strains; Recombinant Proteins; Reference Values; Transfection | 2003 |
Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?
Topics: Animals; Apolipoproteins E; Arginine; Arteriosclerosis; Catalysis; Dietary Supplements; Endothelium, Vascular; Homocysteine; Methylation; Methyltransferases; Mice; Mice, Mutant Strains; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Substrate Specificity | 2003 |
Nutritional modulation of gene expression and homocysteine utilization by vitamin B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Animals; Carcinoma, Hepatocellular; COS Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Kidney; Liver Neoplasms; Methylation; Nucleic Acid Conformation; Nutritional Physiological Phenomena; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured; Vitamin B 12 | 2003 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chlorocebus aethiops; Computational Biology; Conserved Sequence; COS Cells; DNA Primers; Homocysteine; Humans; Hydrolysis; Methylation; Methyltransferases; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylethanolamine N-Methyltransferase; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine; Transfection | 2003 |
Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.
Topics: Cell Transformation, Viral; Cells, Cultured; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Lymphocytes; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin; Tetrahydrofolates | 2003 |
Enzymatic methylation of homocysteine by a synthetic tetrahydrofolate derivative.
Topics: Cysteine; Folic Acid; Homocysteine; Humans; Methylation; Tetrahydrofolates | 1961 |
THE ENZYMATIC METHYLATION OF RIBONUCLEIC ACID AND DEOXYRIBONUCLEIC ACID. V. PURIFICATION AND PROPERTIES OF THE DEOXYRIBONUCLEIC ACID-METHYLATING ACTIVITY OF ESCHERICHIA COLI.
Topics: Alkylation; Carbon Isotopes; Chromatography; Cytosine; DNA; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Homocysteine; Methionine; Methylation; Purines; Research; RNA; RNA, Bacterial; Spectrophotometry | 1964 |
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine | 2004 |
Homocysteine-induced changes in brain membrane composition correlate with increased brain caspase-3 activities and reduced chick embryo viability.
Topics: Animals; Apoptosis; Brain; Caspase 3; Caspases; Chick Embryo; Fatty Acids; Homocysteine; Methylation; Neural Tube Defects; Phospholipids | 2003 |
Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation.
Topics: Amino Acids; Caco-2 Cells; Culture Media; Epithelial Cells; Folic Acid Deficiency; Homocysteine; Humans; Intestinal Mucosa; Intestines; Kinetics; Methionine; Methylation; Serine | 2004 |
Isoprenylcysteine carboxyl methyltransferase modulates endothelial monolayer permeability: involvement of RhoA carboxyl methylation.
Topics: Adenosine; Adherens Junctions; Animals; Cattle; Cell Membrane Permeability; Cells, Cultured; Cysteine; Diterpenes; Electrophoresis, Gel, Two-Dimensional; Endothelial Cells; Green Fluorescent Proteins; Homocysteine; Luminescent Proteins; Methylation; Protein Methyltransferases; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; rhoA GTP-Binding Protein | 2004 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex | 2004 |
Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine.
Topics: Adult; Aged; Case-Control Studies; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 2004 |
S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cell Line, Tumor; Hepatocytes; Homocysteine; Humans; Liver Diseases, Alcoholic; Methylation; Mice; Mice, Inbred C57BL; NF-kappa B; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha | 2004 |
Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.
Topics: Alanine; Animals; Baculoviridae; Binding, Competitive; Catalysis; Cell Line; Dimerization; Dose-Response Relationship, Drug; Genetic Vectors; Genome; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homocysteine; Hydrogen-Ion Concentration; Insecta; Kinetics; Lysine; Mass Spectrometry; Methylation; Mice; Models, Chemical; Models, Genetic; Peptides; Phosphorylation; Protein Isoforms; Protein Methyltransferases; Recombinant Proteins; Substrate Specificity; Temperature; Time Factors | 2004 |
History of emerging vascular disease risk factors.
Topics: Animals; Arteriosclerosis; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Methionine; Methylation; Review Literature as Topic; Risk Factors | 2004 |
Analytical and biochemical aspects associated with supraphysiological creatine intake.
Topics: Animals; Creatine; Dietary Supplements; Homocysteine; Humans; Kidney Function Tests; Methylation | 2005 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis | 2005 |
Defective remethylation of homocysteine is related to decreased synthesis of coenzymes B2 in thyroidectomized rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cystathionine beta-Synthase; Diet; Enzymes; Erythrocytes; Glutathione; Glutathione Reductase; Homocysteine; Hypothyroidism; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Inbred F344; Regression Analysis; Riboflavin; Thyroidectomy; Vitamin B 12 Deficiency | 2005 |
S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling.
Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Catalysis; Cloning, Molecular; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hot Temperature; Kinetics; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrococcus; Pyrococcus furiosus; Recombinant Proteins; Sequence Homology, Amino Acid; Sulfolobus solfataricus; Temperature; Threonine | 2005 |
Folic acid treatment increases homocysteine remethylation and methionine transmethylation in healthy subjects.
Topics: Adult; Amino Acids; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; Vitamins | 2005 |
L-arginine increases plasma homocysteine in apoE-/-/iNOS-/- double knockout mice.
Topics: Animals; Apolipoproteins E; Arginine; Arteriosclerosis; Cell Line; Dietary Supplements; Dose-Response Relationship, Drug; Glycine; Homocysteine; Methionine; Methylation; Mice; Mice, Knockout; Models, Biological; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Risk Factors; Time Factors | 2004 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes.
Topics: Computers; DNA; Epidemiologic Studies; Folic Acid; Genotype; Homocysteine; Humans; Italy; Lymphocytes; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2005 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Effects of homocysteine on the dopaminergic system and behavior in rodents.
Topics: Adenosine; Animals; Behavior, Animal; Brain Chemistry; Catheterization; Chromatography, High Pressure Liquid; Dopamine; Homocysteine; Immunohistochemistry; Injections, Intraventricular; Male; Methylation; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine; Tyrosine 3-Monooxygenase | 2005 |
A coupled fluorescent assay for histone methyltransferases.
Topics: Adenosylhomocysteinase; Coumarins; Fluorescent Dyes; Fluorometry; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homocysteine; Kinetics; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Schizosaccharomyces; Sulfolobus solfataricus | 2005 |
Physiological regulation of phospholipid methylation alters plasma homocysteine in mice.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cell Membrane; Cytidine Diphosphate Choline; Cytosol; Hepatocytes; Homocysteine; Liver; Methionine Adenosyltransferase; Methylation; Methyltransferases; Mice; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 2005 |
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Avitaminosis; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Methylation; Middle Aged; Prevalence | 2005 |
Inhibition of transmethylation disturbs neurulation in chick embryos.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Embryonic Development; Homocysteine; Methylation; Models, Biological; Nervous System; Organogenesis; S-Adenosylhomocysteine; Time Factors; Tubercidin | 2005 |
Evolutionary plasticity of methionine biosynthesis.
Topics: Arabidopsis; Archaea; Bacteria; Evolution, Molecular; Homocysteine; Homoserine; Methionine; Methylation; Models, Biological; Saccharomyces; Schizosaccharomyces | 2005 |
Morphogenetic movements during cranial neural tube closure in the chick embryo and the effect of homocysteine.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Movement; Central Nervous System; Chick Embryo; Homocysteine; Methylation; Neural Tube Defects; Skull | 2005 |
Effects of insulin on methionine and homocysteine kinetics in type 2 diabetes with nephropathy.
Topics: Blood Glucose; Carbon Dioxide; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fasting; Food; Glucose Clamp Technique; Glycated Hemoglobin; Heterozygote; Homocysteine; Homozygote; Humans; Insulin; Kinetics; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Sulfur | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Iron and the folate-vitamin B12-methylation pathway in multiple sclerosis.
Topics: Adult; Anti-Inflammatory Agents; Black People; Dietary Fats; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Interferons; Iron; Magnetic Resonance Imaging; Male; Methylation; Multiple Sclerosis; Nutritional Status; Patient Compliance; Pilot Projects; Prednisone; Vitamin B 12; White People | 2006 |
Distinct effects of folate and choline deficiency on plasma kinetics of methionine and homocysteine in rats.
Topics: Animals; Choline Deficiency; Folic Acid Deficiency; Homocysteine; Kinetics; Male; Methionine; Methylation; Rats; Rats, Sprague-Dawley | 2006 |
Nutrition and metabolism.
Topics: Animals; Homocysteine; Humans; Liver; Methylation; Nutritional Physiological Phenomena; Phosphatidylcholines | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Low fasting methionine concentration as a novel risk factor for recurrent venous thrombosis.
Topics: Adult; Aged; Case-Control Studies; Cysteine; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Odds Ratio; Recurrence; Risk Assessment; Risk Factors; Venous Thrombosis | 2006 |
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors | 2006 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosylhomocysteinase; Apoptosis; Caspase Inhibitors; Caspases; Dipyridamole; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Humans; Methylation; Nucleoside Transport Proteins; Oligonucleotide Array Sequence Analysis; Pentostatin; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Sulfur amino acid metabolism in children with severe childhood undernutrition: methionine kinetics.
Topics: Amino Acids, Sulfur; Carbon Isotopes; Case-Control Studies; Edema; Female; Glutathione; Homocysteine; Humans; Infant; Infant Nutrition Disorders; Infections; Kwashiorkor; Male; Methionine; Methylation; Protein Biosynthesis; Protein-Energy Malnutrition; Proteins | 2006 |
Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract.
Topics: Animals; Carbon Isotopes; Cystathionine beta-Synthase; DNA Primers; Gastrointestinal Tract; Homocysteine; Methionine; Methylation; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Sulfur Compounds; Sus scrofa; Tritium | 2007 |
Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Line, Tumor; Homocysteine; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NIH 3T3 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 2; tau Proteins | 2007 |
Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects.
Topics: Aged; Biomarkers; Caffeine; Cross-Over Studies; Drinking; Eating; Fasting; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Phenols; Polyphenols; Tea; Vitamin B 12 | 2007 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Mice deficient in cystathionine beta synthase display altered homocysteine remethylation pathway.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; Homocysteine; Homocystinuria; Methylation; Mice; MicroRNAs | 2007 |
[Demethylation in the promoter region of MTHFR gene and its mRNA expression in cultured human vascular smooth muscle cells induced by homocysteine].
Topics: Cells, Cultured; Homocysteine; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Muscle, Smooth, Vascular; Promoter Regions, Genetic; RNA, Messenger; Umbilical Arteries | 2007 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc | 2008 |
Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Crystallography, X-Ray; Elasticity; Homocysteine; Metals; Methylation; Methyltransferases; Protein Conformation; Thermotoga maritima; Vitamin B 12; Zinc | 2008 |
The arginine-creatine pathway is disturbed in children and adolescents with renal transplants.
Topics: Adolescent; Arginine; Cardiovascular Diseases; Case-Control Studies; Child; Creatine; Creatinine; Female; Glycine; Homocysteine; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Methylation; Risk Factors | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis.
Topics: Adenosylhomocysteinase; Atherosclerosis; Down-Regulation; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homeostasis; Homocysteine; Humans; Membrane Proteins; Methylation; Myo-Inositol-1-Phosphate Synthase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Repressor Proteins; Risk Factors; S-Adenosylhomocysteine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triglycerides | 2008 |
Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.
Topics: Animals; Disease Susceptibility; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylation; Mice; Mice, Transgenic; Mutation; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
On the methylation of ethanol amine, dimethyl ethanol amine, guanidine acetic acid and homocysteine.
Topics: Acetates; Acetic Acid; Amines; Ethanol; Ethanolamines; Guanidine; Guanidines; Homocysteine; Methylation | 1947 |
Homocysteine is not associated with global motor or cognitive measures in nondemented older Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Cognition; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Inactivation, Metabolic; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Motor Skills; Neuropsychological Tests; Parkinson Disease; Severity of Illness Index; Vitamin B Complex | 2009 |
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
Topics: Animals; Animals, Genetically Modified; Biomarkers; DNA; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Homocysteine; Methylation; Mice; Thymidine Monophosphate; Uracil | 2009 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs.
Topics: Amino Acids, Sulfur; Animals; Animals, Newborn; Cell Division; Cysteine; Enteral Nutrition; Epithelial Cells; Female; Glutathione; Goblet Cells; Homocysteine; Intestinal Mucosa; Iodine Radioisotopes; Methionine; Methionine Adenosyltransferase; Methylation; Models, Biological; Nitrogen Isotopes; Organ Size; Oxidation-Reduction; Sus scrofa; Tritium; Up-Regulation | 2009 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Synergistic effects of homocysteine, S-adenosylhomocysteine and adenosine on apoptosis in BV-2 murine microglial cells.
Topics: Adenosine; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line; Cell Survival; Drug Synergism; Homocysteine; Methylation; Mice; Microglia; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; S-Adenosylhomocysteine | 2008 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Methionine metabolism in human pregnancy.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Homocysteine; Humans; Methionine; Methylation; Pregnancy; Statistics, Nonparametric; Young Adult | 2010 |
Hepatic acyl-coenzyme a:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia.
Topics: Acyl Coenzyme A; Animals; Cholesterol Esters; CpG Islands; Cystathionine beta-Synthase; Diet; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oleic Acid; RNA, Messenger; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2 | 2010 |
Chronic pancreatitis is associated with hyperhomocysteinemia and derangements in transsulfuration and transmethylation pathways.
Topics: Adult; Creatinine; Cysteine; Erythrocytes; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Regression Analysis; Signal Transduction; Sulfates; Sulfur; Young Adult | 2010 |
Regulation of homocysteine metabolism and methylation in human and mouse tissues.
Topics: Animals; Computational Biology; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet.
Topics: Animals; Diet; Dietary Supplements; Erythrocytes; Glutathione; Glutathione Transferase; Homocysteine; Lipid Peroxidation; Methylation; Mice; Oxidative Stress; S-Adenosylmethionine; Superoxide Dismutase; Vitamin B Deficiency | 2010 |
Polymorphisms in one-carbon metabolism pathway genes, urinary arsenic profile, and urothelial carcinoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Arsenic; Cacodylic Acid; Carcinoma, Transitional Cell; Case-Control Studies; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Life Style; Male; Metabolic Networks and Pathways; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Socioeconomic Factors; Taiwan; Urinary Bladder Neoplasms | 2010 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
A methyl-deficient diet fed to rat dams during the peri-conception period programs glucose homeostasis in adult male but not female offspring.
Topics: Animals; Blood Glucose; Choline Deficiency; Female; Glucose; Glucose Tolerance Test; Homeostasis; Homocysteine; Insulin; Male; Malnutrition; Maternal Nutritional Physiological Phenomena; Methylation; Nutritional Status; Rats; Sex Characteristics | 2011 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine.
Topics: Adipokines; Adult; Aged; Calorimetry, Indirect; Case-Control Studies; Cysteine; Fatty Liver; Female; Glutathione; Homocysteine; Humans; Inflammation Mediators; Insulin Resistance; Liver; Male; Methionine; Methylation; Middle Aged; Non-alcoholic Fatty Liver Disease; Phenylalanine; Proteins; Urea; Young Adult | 2011 |
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.
Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins | 2011 |
High bone concentrations of homocysteine are associated with altered bone morphology in humans.
Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Collagen; Extracellular Matrix; Female; Femur; Hip; Homocysteine; Humans; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1α by PRMT1 and SIRT1.
Topics: Acetylation; Animals; Apoptosis; Cardiomyopathies; Cell Respiration; Energy Metabolism; ERRalpha Estrogen-Related Receptor; Fatty Acids; Female; Folic Acid; Homocysteine; Methylation; Mitochondria, Heart; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Positron-Emission Tomography; PPAR alpha; Protein-Arginine N-Methyltransferases; Proteomics; Rats; Rats, Wistar; Receptors, Estrogen; RNA-Binding Proteins; Sirtuin 1; Stress, Physiological; Transcription Factors; Vitamin B Deficiency | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives.
Topics: Adult; Betaine; Blood Pressure; Catecholamines; Female; Homocysteine; Humans; Hypertension; Indicators and Reagents; Male; Methylation; Niacinamide; Vitamins | 2012 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
Topics: Animals; Biomarkers; Brain; Folic Acid Deficiency; Formates; Homocysteine; Hyperhomocysteinemia; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methionine; Methylation; Methylmalonic Acid; Models, Biological; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2012 |
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha | 2012 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures.
Topics: Aged; Bone Density; Female; Homocysteine; Humans; Incidence; Linear Models; Methylation; Middle Aged; Netherlands; Osteoporotic Fractures; Proportional Hazards Models; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Homocysteinylated protein levels in internal mammary artery (IMA) fragments and its genotype-dependence. S-homocysteine-induced methylation modifications in IMA and aortic fragments.
Topics: Aged; Amidohydrolases; Aorta; Atherosclerosis; Coronary Artery Bypass; Female; Gene Expression; Genotype; Homocysteine; Humans; Male; Mammary Arteries; Methylation; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Promoter Regions, Genetic | 2012 |
Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects.
Topics: Apoptosis; Child; Child, Preschool; Ferredoxin-NADP Reductase; Fibroblasts; Gene Expression Regulation; Genotype; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; MAP Kinase Kinase 4; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation | 2013 |
Early methyl donor deficiency produces severe gastritis in mothers and offspring through N-homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation.
Topics: Animals; Animals, Newborn; Animals, Suckling; Cadherins; Cytoskeletal Proteins; Female; Fetus; Gastritis; Homocysteine; Inflammation; Methylation; Mothers; Oxidative Stress; Pregnancy; Rats; Rats, Wistar; Severity of Illness Index; Signal Transduction | 2013 |
Homocysteine-induced hypermethylation of DDAH2 promoter contributes to apoptosis of endothelial cells.
Topics: Amidohydrolases; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Survival; Coloring Agents; Endothelial Cells; Homocysteine; Methylation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Repressor Proteins; Tetrazolium Salts; Thiazoles | 2013 |
Gestational methyl donor deficiency alters key proteins involved in neurosteroidogenesis in the olfactory bulbs of newborn female rats and is associated with impaired olfactory performance.
Topics: Animals; Animals, Newborn; Apoptosis; Aromatase; Diet; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression; Homocysteine; Lactation; Male; Methylation; Neurogenesis; Neurotransmitter Agents; Olfaction Disorders; Olfactory Bulb; Phosphoproteins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Weaning | 2014 |
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency.
Topics: Animals; Arginine; Brain; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Histones; Homocysteine; Homocystinuria; Liver; Methylation; Mice; S-Adenosylhomocysteine | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.
Topics: Cell Adhesion; Endothelial Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Leukocytes; Methylation; Methyltransferases; Oxidative Stress; RNA, Transfer, Amino Acyl; RNA, Transfer, Ser; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium; Selenoproteins | 2014 |
Increased methylation demand exacerbates ethanol-induced liver injury.
Topics: Alcohol Drinking; Amidinotransferases; Animals; Chemical and Drug Induced Liver Injury; Diet; Ethanol; Fatty Liver, Alcoholic; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2014 |
An alternative mechanism for guanidinoacetic acid to affect methylation cycle.
Topics: Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Humans; Insulin; Methylation | 2014 |
Crosstalk of homocysteinylation, methylation and acetylation on histone H3.
Topics: Acetylation; Amino Acid Sequence; HCT116 Cells; HEK293 Cells; Histones; Homocysteine; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Methylation; Molecular Sequence Data; Protein Processing, Post-Translational | 2015 |
Reversed phase and cation exchange liquid chromatography with spectrophotometric and elemental/molecular mass spectrometric detection for S-adenosyl methionine/S-adenosyl homocysteine ratios as methylation index in cell cultures of ovarian cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Reverse-Phase; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Female; Homocysteine; Humans; Methylation; Molecular Weight; Ovarian Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a.
Topics: Animals; Base Sequence; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Down-Regulation; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Homocysteine; Humans; Liver; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins | 2015 |
Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet.
Topics: Animals; Case-Control Studies; Gene Expression; Homocysteine; Male; Metabolic Networks and Pathways; Methionine; Methylation; Quercetin; Rats; Rats, Wistar | 2015 |
Changes in Carboxy Methylation and Tyrosine Phosphorylation of Protein Phosphatase PP2A Are Associated with Epididymal Sperm Maturation and Motility.
Topics: Animals; Catalysis; Cattle; DNA Methylation; Epididymis; Glycogen Synthase Kinase 3; Homocysteine; Leucine; Male; Methylation; Microcystins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Structure, Tertiary; Sepharose; Sperm Maturation; Sperm Motility; Spermatozoa; Tyrosine | 2015 |
Chemoselective synthesis of functional homocysteine residues in polypeptides and peptides.
Topics: Alkylation; Biomimetic Materials; Homocysteine; Hydrogen-Ion Concentration; Methionine; Methylation; Peptides; Sulfonium Compounds | 2016 |
Plasma homocysteine involved in methylation and expression of thrombomodulin in cerebral infarction.
Topics: Adult; Aged; Aged, 80 and over; Brain; Cerebral Infarction; DNA Methylation; Gene Expression Regulation; Homocysteine; Humans; Methylation; Middle Aged; Thrombomodulin | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult | 2017 |
Influence of phenylketonuria's diet on dimethylated arginines and methylation cycle.
Topics: Arginine; Biomarkers; Child; Chromatography, High Pressure Liquid; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Mass Spectrometry; Methylation; Patient Compliance; Phenylketonurias; Severity of Illness Index; Vitamin B 12 | 2017 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
Homocysteine upregulates interleukin-17A expression via NSun2-mediated RNA methylation in T lymphocytes.
Topics: Animals; Cells, Cultured; Gene Expression Regulation; Homocysteine; Interleukin-17; Methylation; Methyltransferases; Rats; RNA, Messenger; T-Lymphocytes; Up-Regulation | 2017 |
SULPHUR-CONTAINING AMINO ACIDS METABOLISM IN EXPERIMENTAL HYPER- AND HYPOTHYROIDISM IN RATS.
Topics: Adenosylhomocysteinase; Amino Acids, Sulfur; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Homocysteine; Hydrogen Sulfide; Hyperthyroidism; Hypothyroidism; Kidney; Liver; Male; Methionine Adenosyltransferase; Methylation; Rats; Transaminases | 2017 |
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming | 2018 |
Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study.
Topics: Arsenic; Arsenicals; Bangladesh; Case-Control Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Methylation; Polymorphism, Single Nucleotide; Skin Diseases | 2018 |
Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium longum; Biomarkers; Depression; Dopamine; Dopamine Antagonists; Freeze Drying; Hippocampus; Homocysteine; Lactobacillus helveticus; Liver; Male; Methylation; Neurons; Norepinephrine; Prefrontal Cortex; Probiotics; Random Allocation; Rats, Mutant Strains; S-Adenosylmethionine | 2018 |
Demethylation of methionine and keratin damage in human hair.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Copper; Female; Hair; Homocysteine; Humans; Infant; Iron; Keratins; Male; Methionine; Methylation; Middle Aged | 2018 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine | 2018 |
Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.
Topics: Adult; Arsenic; Biomarkers; Cohort Studies; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylation; Mexico; Pregnancy; Pregnant Women; Regression Analysis; Vitamin B 12; Young Adult | 2018 |
Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase.
Topics: Animals; Carbon-Nitrogen Ligases; Folic Acid; Histidine; Homocysteine; Humans; Methylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases | 2018 |
Two-carbon folate cycle of commensal Lactobacillus reuteri 6475 gives rise to immunomodulatory ethionine, a source for histone ethylation.
Topics: Amino Acids; Carbon; Cell Proliferation; Cells, Cultured; Culture Media; Ethionine; Folic Acid; Histones; Homocysteine; Humans; Immunomodulation; Limosilactobacillus reuteri; Methionine; Methylation; Microbiota; Probiotics; THP-1 Cells; Tumor Necrosis Factor-alpha | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling.
Topics: Cytosol; Gene Regulatory Networks; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Protein Interaction Maps; Protein Transport | 2020 |
Identification and characterization of a bacterial core methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Chloroflexi; Dehalococcoides; Escherichia coli; Genome, Bacterial; Homocysteine; Methionine; Methylation; Phylogeny; Vitamin B 12 | 2020 |
The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats.
Topics: Animals; Homocysteine; Humans; Hypothyroidism; Liver; Methylation; Rats; S-Adenosylmethionine; Vitamin B Complex | 2020 |
Association between gene promoter methylation of the one-carbon metabolism pathway and serum folate among patients with hyperhomocysteinemia.
Topics: Carbon; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylation; Promoter Regions, Genetic | 2020 |
Laboratory evaluation of homocysteine remethylation disorders and classic homocystinuria: Long-term follow-up using a cohort of 123 patients.
Topics: Betaine; Cystathionine beta-Synthase; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Laboratories; Methionine; Methylation | 2020 |
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4.
Topics: Animals; Ferroptosis; Homocysteine; Hyperhomocysteinemia; Methylation; Mice; Nucleus Pulposus; Oxidative Stress; Rats | 2020 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1.
Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element | 2021 |
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine | 2022 |
Effect of Beer Consumption on Methylation and Redox Metabolism.
Topics: Antioxidants; Apolipoproteins; Beer; Betaine; Cholesterol, LDL; Folic Acid; Homocysteine; Humans; Male; Methylation; Oxidation-Reduction; Superoxide Dismutase; Uric Acid; Vitamin B 6 | 2022 |
Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Topics: Adult; Arsenic; Arsenicals; Biomarkers; Birth Weight; Carbon; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2022 |