isomethyleugenol has been researched along with guanine in 465 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 291 (62.58) | 18.7374 |
| 1990's | 109 (23.44) | 18.2507 |
| 2000's | 33 (7.10) | 29.6817 |
| 2010's | 22 (4.73) | 24.3611 |
| 2020's | 10 (2.15) | 2.80 |
| Authors | Studies |
|---|---|
| Lakings, DB; Mrochek, JE; Waalkes, TP | 1 |
| Wong, JL; Zady, MF | 1 |
| Berech, J; Keegan, FP | 1 |
| Bertram, B; Eisenbrand, G; Krüger, FW | 1 |
| Stuart, WD; Woodward, DO | 1 |
| Germershausen, J; Goodman, D; Somberg, EW | 1 |
| Robins, PE; Schendel, PF | 1 |
| Felsenfeld, G; McGhee, JD | 1 |
| Lipmann, F; Mizumoto, K | 1 |
| Debov, SS; Lopatina, NG; Nikol'skaia, II | 1 |
| Beabealashvilli, R; Melnikova, AF; Mirzabekov, AD | 1 |
| Abbott, PJ; Saffhill, R | 1 |
| Ivanov, VI; Kolchinsky, AM; Minchenkova, LE; Volkenstein, MV; Vorlícková, M; Zavriev, SK | 1 |
| Chang, MJ; Koestner, A; Webb, TE | 1 |
| Cox, R; Irving, CC | 1 |
| Thielmann, HW | 1 |
| Buecheler, J; Cooper, HK; Diessner, H; Kleihues, P; Kolar, GF | 1 |
| Brown, R; Joseph, M; Leigh, T; Swain, ML | 1 |
| Brown, DD; Brownlee, GG; Cartwright, EM; Fedoroff, NV; Miller, JR | 1 |
| Bird, AP; Southern, EM | 1 |
| Bird, AP | 1 |
| Hui, G; Pegg, AE | 1 |
| Pegg, AE | 4 |
| Cooper, HK; Hauenstein, E; Kleihues, P; Kolar, GF | 1 |
| Chapleo, MR; Galbraith, AI; Itzhaki, RF | 1 |
| Hui, G; Pegg, AE; Rogers, KJ | 1 |
| Margison, GP; Montesano, R; Pegg, AE; Stumpf, R | 1 |
| Bücheler, J; Cooper, HK; Kleihues, P; Swenberg, JA | 1 |
| Shugart, L | 1 |
| Balis, ME; Maschio, FA; Tscherne, JS; Wainfan, E | 1 |
| Salas, CE; Sellinger, OZ | 1 |
| Autrup, H; Harris, CC; McDowell, EM; Schafer, P; Stoner, GD; Trump, BF | 1 |
| Likhachev, AJ; Margison, GP; Montesano, R | 1 |
| King, LJ; Wooder, MF; Wright, AS | 1 |
| Ianson, IK; Sukhodub, LF; Verkin, BI | 1 |
| Nicoll, JW; Pegg, AE; Swann, PF | 1 |
| Frei, JV; Lawley, PD | 1 |
| Margison, GP; O'Connor, PJ | 1 |
| Barbier, M; Kerr, SJ; Lederer, E; Tekitek, A | 1 |
| Kaspersen, FM; Pandit, UK | 1 |
| Kleihues, P; Kolar, GF; Margison, GP | 1 |
| Hankinson, O; Watson, AJ | 1 |
| de los Santos, H; Spratt, TE | 1 |
| Gualberto, A; Walsh, K | 1 |
| Gutowski, JC; Schreier, HJ | 1 |
| Den Otter, W; Gloudemans, T; Lips, CJ; Pospiech, I; Schneid, H; Sussenbach, JS; Van Der Ven, LT | 1 |
| Gundersen, G; Larsen, F; Prydz, H | 1 |
| Bartsch, H; Bouvier, G; Chen, CS; Hautefeuille, A; Malaveille, C; Pignatelli, B; Shuker, D; Zhang, RF | 1 |
| Cairns-Smith, S; Karran, P | 1 |
| Fujii, T; Inagaki, J; Itaya, T; Nishii, M; Nohara, F; Ogawa, K; Saito, T | 1 |
| Castonguay, A; Gerson, SL; Liu, L | 1 |
| Beatty, LG; Panigrahi, GB; Sadowski, PD | 1 |
| Graves, R; Laval, J; Pegg, AE | 1 |
| Andrews, NC; Higgs, DR; Orkin, SH; Strauss, EC | 1 |
| Gualberto, A; Patrick, RM; Walsh, K | 1 |
| Kokkinakis, DM | 1 |
| Archer, MC; Chaulk, EJ; Lu, SJ | 1 |
| Bignami, M; Karran, P | 2 |
| Boiteux, S; Laval, J; Tudek, B | 1 |
| Archer, MC; Lu, SJ; Milligan, JR | 1 |
| Gilbert, W; Sen, D | 2 |
| Lilley, DM; Murchie, AI | 1 |
| Berman, J; Petracek, ME | 1 |
| Chen, JS; Guo, ZL; Liu, ZQ; Xiao, Y; Zhu, JQ | 1 |
| Elding, LI; Reedijk, J; Struik, AF; van Boom, JH; Zuiderwijk, CT | 1 |
| Boublik, M; Ofengand, J; Tumminia, SJ; Weitzmann, C | 1 |
| Alexander, JA; McCain, DM; Rose, LM; Shealy, YF; Struck, RF | 1 |
| Keefer, LK; Kleihues, P; Nims, RW; Reist, EJ; Schmerold, I; von Hofe, E | 1 |
| Hecht, SS; Peterson, LA | 1 |
| Den Engelse, L; Scherer, E; Van Benthem, J; Vermeulen, E; Wild, CP | 1 |
| Aïssani, B; Bernardi, G | 1 |
| Bax, H; Scherer, E; van Benthem, J | 1 |
| Hemminki, K; Mustonen, R | 1 |
| Hepburn, PA; Margison, GP; Tisdale, MJ | 1 |
| Bird, A; Cross, S; Kovarik, P; Schmidtke, J | 1 |
| el-Bayoumy, K; Fiala, ES; Joseph, C; Reddy, BS; Sohn, OS | 1 |
| Huang, JZ; Schell, MA | 1 |
| Baan, RA; Claassen, E; Schellekens, MM; van Delft, JH; van Weert, EJ | 1 |
| Archer, MC; Chin, W; Cooper, DP; Dai, WD; Lee, V; O'Connor, PJ | 1 |
| Ge, G; Georghiou, S; Huang, CR; Weidner, R; Zhu, S | 1 |
| Kerr, SJ | 2 |
| Lobell, RB; Schleif, RF | 1 |
| Li, BF; Tan, NW | 1 |
| Anderson, MW; Belinsky, SA; Foley, JF; Maronpot, RR; White, CM | 1 |
| Gupta, S; Reddy, R; Singh, R | 1 |
| Lawson, TA | 1 |
| Bianchi, MS; Bianchi, NO; Larramendy, M | 1 |
| Harasawa, R; Higashi, T | 1 |
| Archer, MC; Catz-Biro, L; Hirani-Hojatti, S; Milligan, JR | 1 |
| Pratviel, G; Sartorelli, AC; Shyam, K | 1 |
| Baker, DJ; Jardines, LA; Smith, SS | 1 |
| Cawkwell, L; Georgiadis, P; Margison, GP; Patel, D; Potter, PM; Swann, PF; Wilkinson, MC | 1 |
| Adams, CC; Caplan, AJ; Fishel, BR; Garrard, WT; Gross, DS; Lee, MS; McDaniel, D | 1 |
| Cowing, DW; Gross, CA; Mecsas, J; Record, MT | 1 |
| Murphy, SE | 1 |
| Alaoui-Jamali, MA; Castonguay, A; Rossignol, G; Schuller, HM | 1 |
| Astell, CR; Blundell, MC | 1 |
| Imokawa, M; Sager, R; Sano, H | 1 |
| Clark, JH; Greene, GL; Klein-Hitpass, L; O'Malley, BW; Tsai, MJ; Tsai, SY | 1 |
| Clark, EA; Fox, MS; Radicella, JP | 1 |
| Nakabeppu, Y; Otsuka, M; Sekiguchi, M | 1 |
| Kilpatrick, MW; Lindahl, T; McCarthy, TV; Sedgwick, B; Teo, I | 1 |
| Brennan, CA; Gumport, RI; Van Cleve, MD | 2 |
| Keith, DH; Riggs, AD; Singer-Sam, J | 1 |
| Brown, TC; Jiricny, J | 1 |
| Janzer, RC; Kleihues, P; Kolar, GF; Meer, L | 1 |
| Abbondandolo, A; Bignami, M; Calcagnile, A; Dogliotti, E; Frosina, G; Terlizzese, M; Zijno, A | 1 |
| Ames, BN; Park, JW | 1 |
| Barch, DH; Fox, CC | 1 |
| Farmer, PB; Franke, H; Parry, A; Schmid, J | 1 |
| Tacchi-Bedford, AM | 1 |
| Clark, W; Olson, WK; Srinivasan, AR; Torres, R | 1 |
| Ehrlich, KC; Ehrlich, M; Shenoy, S | 1 |
| Lambert, CE; Shank, RC | 1 |
| Dolan, ME; Pegg, AE; Scicchitano, D | 1 |
| Alvord, WG; Bosan, W; Koepke, SR; Kroeger-Koepke, MB; Michejda, CJ; Thomas, BJ | 1 |
| Anisimov, V; Likhachev, A; Petrov, A; Zhukovskaya, N | 1 |
| Dervan, PB; Iverson, BL | 1 |
| Anderson, MW; Belinsky, SA; Devereux, TR | 1 |
| Anderson, MW; Darden, TA; Deerfield, DW; Hoel, DG; Pedersen, LG | 1 |
| Hall, J; Karran, P; Kataoka, H; Stephenson, C | 1 |
| Dixit, R; Gold, B | 1 |
| Shank, RC | 3 |
| Barrows, LR | 1 |
| Jiricny, J; Martin, D; Ubasawa, A; Wood, SG | 1 |
| Droogmans, L; Grosjean, H | 1 |
| Georghiou, S; Saim, AM | 1 |
| Bailey, E; Farmer, PB; Shuker, DE | 2 |
| Adams, JD; Hoffmann, D; LaVoie, EJ; Prokopczyk, G | 1 |
| Keefer, LK; Kleihues, P; Lijinsky, W; Schmerold, I; von Hofe, E | 1 |
| Billett, MA; O'Connor, PJ; Ryan, AJ | 1 |
| Kawarada, Y; Okuhara, E | 1 |
| Bosan, WS; Gaworski, CL; MacEwen, JD; Newberne, PM; Shank, RC | 1 |
| Day, RS; DiPaolo, JA; Doniger, J | 1 |
| Church, GM; Ephrussi, A; Gilbert, W; Tonegawa, S | 1 |
| Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N | 1 |
| Bird, I; Farmer, PB; Shuker, EG | 1 |
| Fridey, SM; Parthasarathy, R | 1 |
| Bosan, WS; Lambert, CE; Shank, RC | 2 |
| Hochschild, A; Ptashne, M | 1 |
| Archer, MC; Silinskas, KC; Zucker, PF | 1 |
| Bolt, HM; Laib, RJ; Ottenwälder, H; Peter, H; Rupprich, N; Topp, H | 1 |
| Sakai, K; Umeda, T; Yamane, Y | 1 |
| Bolden, AH; Nalin, CM; Ward, CA; Weissbach, A | 1 |
| Haerlin, R; Süssmuth, R | 1 |
| Krüger, FW; Rücker, U; Wiessler, M | 1 |
| Krüger, FW; Osswald, H; Schelten, E; Walker, G | 1 |
| Dannenberg, H; Gross, HJ; Weyland, P | 1 |
| Nemoto, N; Takayama, S | 3 |
| Bertram, B; Krüger, FW | 1 |
| Krüger, FW | 1 |
| Boudet, J; Leng, M; Rosilio, C | 1 |
| Borek, E; Kerr, SJ; Sharma, OK | 1 |
| Bryant, JA; Wildon, DC | 1 |
| Spielvogel, RL; Turkington, RW | 1 |
| Bryan, GT; Skibba, JL | 1 |
| Gantt, RR; Montes de Oca, F; Stromberg, KJ | 1 |
| Granieri, A; Scarano, E; Tosi, L | 1 |
| Lawley, PD; Shah, SA | 3 |
| Katzman, PA; Munns, TW; Podratz, KC | 2 |
| McFarlane, ES | 1 |
| Capps, MJ; Craig, AW; Lawley, PD; O'Connor, PJ; Shah, SA | 1 |
| Craddock, VM | 4 |
| Nau, F | 1 |
| Ho, Y; Lin, HJ | 1 |
| Kleihues, P; Margison, GP; Mende, C; Patzschke, K; Wegner, LA | 1 |
| Inose, M; Iwanami, Y | 1 |
| Lingens, F; Rau, J; Süssmuth, R | 1 |
| Tomasz, M | 1 |
| Goth, R; Rajewsky, MF | 1 |
| Kleihues, P; Margison, GP | 1 |
| Kazimierczuk, Z; Shugar, D | 1 |
| Haerlin, R; Lingens, F; Süssmuth, R | 1 |
| Hidalgo, C; Nash, HA | 1 |
| Pickering, WR; Woods, RA | 1 |
| Dudock, B; Michael, M; Roe, B | 1 |
| Krasna, AI; Trifunac, NP | 1 |
| Löforth, G; Wennerberg, R | 1 |
| Engel, JD; von Hippel, PH | 1 |
| Graham, DE; Skinner, DM | 1 |
| Brown, GB; Sutherland, DR | 1 |
| Capps, MJ; Craig, AW; O'Connor, PJ | 1 |
| Capps, MJ; Craig, AW; Margison, GP; O'Connor, PJ | 1 |
| Kleihues, P; Magee, PN | 1 |
| Gerchman, LL; Ludlum, DB | 1 |
| Gantt, R; Julian, B | 1 |
| Belozersky, AN; Mazin, AL; Vanyushin, BF; Vasilyev, VK | 1 |
| Borovkova, TV; Fedorov, NA; Kaloshina, GA | 1 |
| Lu, T; Nelson, JH; Sheid, B | 1 |
| Hadjiolov, D; Mundt, D | 1 |
| Boutwell, RK; Bowden, GT | 1 |
| Löfroth, G; Osterman-Golkar, S; Wennerberg, R | 1 |
| Eagles, J; Roos, IA; Thomson, AJ | 1 |
| Dubin, DT; Friend, DA | 1 |
| Mizuno, NS; Nagasawa, HT; Shirota, FN | 1 |
| Nikolskaya, II; Tikchonenko, TI; Tkatcheva, ZG; Vanyushin, BF | 1 |
| Björk, GR; Svensson, I | 2 |
| Björk, GR; Lundahl, P; Svensson, I | 1 |
| Russell, NL; Smith, DW | 1 |
| Moore, BG | 1 |
| Fürer, E; Hendler, S; Srinivasan, PR | 1 |
| Björk, GR; Isaksson, LA | 1 |
| Baguley, BC; Staehelin, M | 1 |
| Kuchino, Y; Nishimura, S; Seno, T | 1 |
| Hattman, SM; Revel, HR | 1 |
| Lawley, PD; Orr, DJ | 1 |
| Arikawa, S; Zamenhof, S | 1 |
| Thorne, CB; Yelton, DB | 1 |
| Leng, M; Ramstein, J; Reynaud, JA | 1 |
| Morrison, MR; Williamson, R | 1 |
| Den Engelse, L; Emmelot, P | 1 |
| Hawks, A; Magee, PN; Swann, PF | 1 |
| Chan, SI; Kreishman, GP; Lee, GC; Schmidt, CF | 1 |
| Brown, GB; Watson, AA | 1 |
| Ahonen, J; Kivisaari, J; Kulonen, E; Välimăki, M; Vastamäki, M | 1 |
| Graffi, A; Tetzlaff, I; Wunderlich, V | 1 |
| Leng, M; Ramstein, J | 1 |
| Eistetter, K; Pfleiderer, W; Shanshal, M | 1 |
| Héléne, C; Leng, M; Ramstein, J | 1 |
| Kloos, WE; Morrison, SJ; Tornabene, TG | 1 |
| Borek, E; Scarborough, GA; Wong, RS | 1 |
| Craig, AW; O'Connor, PJ | 1 |
| Birdsall, NJ; Delia, TJ; Lee, TC; Parham, JC | 1 |
| Brown, GB; Parham, JC; Winn, TG | 1 |
| von Philipsborn, W; Wagner, R | 1 |
| Craig, AW; McElhone, MJ; O'Connor, PJ | 1 |
| McLean, AE; Swann, PF | 1 |
| Borek, E; Loeb, LA; Sharma, OK | 1 |
| Gehrke, CW; Lakings, DB | 1 |
| Rogers, GT; Ulbricht, TL | 1 |
| Ivankovic, S; Krüger, FW; Preissler, P; Schmähl, D | 1 |
| Griffin, AC; Saunders, GF; Shirakawa, S | 1 |
| Matsumoto, H; Nagata, Y | 1 |
| Whittle, ED | 1 |
| Brown, GM; Culp, LA; Dore, E | 1 |
| Lawley, PD; Thatcher, CJ | 1 |
| Biempica, L; Bilik, E; Sheid, B | 1 |
| Hattman, S | 1 |
| Michelson, AM; Pascal, Y; Pitha, P; Pochon, F | 1 |
| Eagles, J; Howlett, HA; Johnson, MW; Self, R; Trim, AR | 1 |
| Newton, AA; Rubery, ED | 1 |
| Frei, JV | 1 |
| Craddock, VM; Magee, PN; Villa-Trevino, S | 1 |
| Fraenkel-Conrat, H; Greenberg, J; Michelson, AM; Singer, B | 1 |
| Brookes, P; Craddock, VM; Lawley, PD; Magee, PN; Swann, PF | 1 |
| Craddock, VM; Magee, PN; Mattocks, AR | 1 |
| Magee, PN; Swann, PF | 1 |
| Robins, MJ; Robins, RK | 1 |
| McCalla, DR; Olson, AO | 1 |
| Fraenkel-Conrat, H; Singer, B | 1 |
| Swann, PF | 1 |
| Miertus, S; Trebatická, M | 1 |
| Rajalakshmi, S; Rao, RM; Sarma, DS | 1 |
| Paz-Neri, LL; Quintero-Ruiz, A; Villa-Treviño, S | 1 |
| Adam, Y; Hegazi, B; Mostafa, IY; Zayed, SM | 1 |
| Banerjee, AK | 1 |
| Columbano, A; Ledda, GM; Rajalakshmi, S; Rao, PM; Sarma, DS | 2 |
| Bynum, GD; Day, RS; Galloway, SM; Girardi, AJ; Lubiniecki, AS; Meyer, SA; Scudiero, DA; Ziolkowski, CH | 1 |
| Robert-Géro, M; Vedel, M | 1 |
| Grossman, L | 1 |
| Nigon, VM; Poncet, D; Verdier, G | 1 |
| Jones, KA; Tjian, R | 1 |
| Dolan, ME; Pegg, AE; Scicchitano, D; Singer, B | 1 |
| Harada, F; Kato, N; Miura, K; Tsuda, S; Ueda, T | 1 |
| Huang, SS; Pontzer, NJ; Shaikh, B | 1 |
| Bailey, E; Farmer, PB; Gorf, SM; Lamb, J; Shuker, DE | 1 |
| Dedek, W; Grahl, R; Schmidt, R | 1 |
| Nur, I; Razin, S; Rottem, S | 1 |
| Gaffney, BL; Jones, RA; Marky, LA | 1 |
| Autrup, H; James, JT | 1 |
| Bosan, WS; Shank, RC | 1 |
| Huber, KW; Lutz, WK | 1 |
| Day, RS; Yagi, T; Yarosh, DB | 1 |
| Ivankovic, S; Kleihues, P; Rice, JM; Wiestler, OD | 1 |
| Brunke, KJ; Leboy, PS; Strickler, G | 1 |
| Becker, Y; Shiloh, Y; Tabor, E | 1 |
| Foote, RS; Mitra, S; Pal, BC | 1 |
| Buck, HM; Smits, MT; Van Lier, JJ | 1 |
| Jones, RA; Kuzmich, S; Marky, LA | 1 |
| Bresil, H; Margison, G; Montesano, R; Pegg, AE; Planche-Martel, G | 1 |
| Asbery, LJ; Chandler, PM; Harris, G; Jones, MG; Lawley, PD | 1 |
| Alekandrov, VA; Anisimov, VN; Bespalov, VG; Korsakov, MV; Likhachev, AJ; Napalkov, NP; Ovsyannikov, AI; Popovich, IG; Tomatis, L | 1 |
| Cao, EH; Cronkite, EP; Miller, ME; Setlow, RB; Waldstein, EA | 1 |
| Cao, EH; Setlow, RB; Waldstein, EA | 1 |
| Lindahl, T; Olsson, M | 1 |
| Laval, F; Laval, J; Pierre, J | 1 |
| Margison, GP; Pegg, AE | 1 |
| Karran, P; Marinus, MG | 1 |
| Barrows, LR; Magee, PN | 1 |
| Jeffrey, A; Krovatin, W; Pabo, CO; Sauer, RT | 1 |
| Kanduc, D | 1 |
| Hopfinger, AJ; Karasawa, Y; Kikuchi, O; Suzuki, K | 1 |
| Hayatsu, H; Negishi, K; Tomita, K; Yamagata, Y; Yamashita, Y; Yui, S | 1 |
| Giercksky, KE; Krokan, H; Myrnes, B | 1 |
| Lindahl, T; Rydberg, B | 1 |
| Cedar, H; Gruenbaum, Y; Razin, A; Stein, R | 1 |
| Der, O; Sellinger, OZ | 1 |
| Pegg, AE; Perry, W | 2 |
| Likhachev, AIa; Petrov, AS | 2 |
| Harris, G; Lawley, PD; Olsen, I | 1 |
| Margison, GP | 1 |
| Bogden, JM; Bresnick, E; Eastman, A | 1 |
| Herron, DC; Shank, RC | 2 |
| Becker, Y; Shiloh, Y | 1 |
| Barrows, LR; Becker, RA; Shank, RC | 1 |
| Wooder, MF; Wright, AS | 1 |
| Dainat, J; Sellinger, OZ | 1 |
| Craig, AW; Galbraith, AI; Itzhaki, RF; Margison, GP | 1 |
| Archer, MC; Leung, KH; Park, KK | 1 |
| Hanski, C; Stehlik, G | 1 |
| Asakura, H; Kominami, R; Mishima, Y; Suda, T | 1 |
| Fry, M; Nadel, Y; Weisman-Shomer, P | 1 |
| den Engelse, L; Feron, VJ; Leeman, WR; Scherer, E; Van Benthem, J; Vermeulen, E; Wilmer, JW | 1 |
| Agrawal, S; Kandimalla, ER | 1 |
| Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG | 1 |
| Azorín, F; Jiménez-García, E; Martínez-Balbás, MA | 1 |
| Fiala, ES; Sohn, OS | 1 |
| Bean, CL; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB | 1 |
| Edara, S; Goodtzova, K; Kanugula, S; Pegg, AE | 1 |
| Laayoun, A; Smith, SS; Turk, PW; Weitzman, SA | 1 |
| Aquilina, G; Bignami, M; Ceccotti, S; Fiumicino, S; Hess, P | 1 |
| Koenig, RJ; Subauste, JS; Yang, YZ | 1 |
| Gradia, S; Hecht, SS; Peterson, LA; Ronai, ZA | 1 |
| Cooper, S; Denizeau, F; Fadlallah, S; Fournier, M; Guertin, F; Krzystyniak, K; Lachapelle, M | 1 |
| Jin, A; Nelson, M; Traylor, E; Van Etten, JL; Xia, Y; Zhang, Y | 1 |
| Brooks, C; Mitra, S; Roy, R | 1 |
| Kohda, K; Terashima, I; Yamagami, N; Yamagata, Y | 1 |
| Bianchini, F; Wild, CP | 1 |
| Fox, KR; Washbrook, E | 1 |
| Mathison, BH; Murphy, SE; Shank, RC | 1 |
| Davidson, RL; Kresnak, M | 1 |
| Panigrahi, GB; Sadowski, PD | 1 |
| Branch, P; Griffin, S; Karran, P; Xu, YZ | 1 |
| MacDonald, RJ; Rose, SD; Swift, GH | 1 |
| Douskey, MC; Gold, B; Wurdeman, RL | 1 |
| Dahlberg, JE; Terns, MP | 1 |
| Giraldo, R; Rhodes, D | 1 |
| Brar, RS; Bull, AW | 1 |
| Aquilina, G; Bignami, M; Biondo, R; Dogliotti, E | 1 |
| Noller, HF; von Ahsen, U | 1 |
| Bolt, HM; Gansewendt, B; He, HZ; Peter, H; Xu, DG; Zhang, GG | 1 |
| McGrew, MJ; Rosenthal, N | 1 |
| Bignami, M; Ceccotti, S; Dogliotti, E; Gannon, J; Karran, P | 1 |
| Bentivegna, SS; Bresnick, E | 1 |
| Hershko, A; Kafri, T; Razin, A | 1 |
| Barnes, DE; Lindahl, T; Sedgwick, B | 1 |
| Chiu, SK; Radding, CM; Rao, BJ | 1 |
| Agresti, A; Archidiacono, N; Corneo, G; Della Valle, G; Ginelli, E; Marozzi, A; Meneveri, R; Rocchi, M; Saccone, S | 1 |
| Barak, R; Bel, P; Chedda, GB; Dutta, SP; Vincze, A | 1 |
| Busby, S; Minchin, S | 1 |
| Mathison, BH; Said, B; Shank, RC | 1 |
| Baylin, SB; Harris, CC; Spillare, EA; Vertino, PM | 1 |
| Bartůnĕk, P; Dvorák, M; Kaspar, P | 1 |
| Chung, FL; Huang, Q; Lawson, TA; Mervish, SS; Morris, CR | 1 |
| Bednarik, DP; Brady, JN; Gutekunst, KA; Kashanchi, F | 1 |
| Hecht, SS; Liu, XK; Peterson, LA | 1 |
| Avery, LJ; LeDoux, SP; Patton, NJ; Wilson, GL | 1 |
| Badawi, AF; Cooper, DP; Hall, CN; Jackson, PE; O'Connor, PJ; Povey, AC | 1 |
| Algarté, M; Goldring, CE; Jeannin, JF; Reveneau, S | 1 |
| Halliwell, B; Kaur, H | 1 |
| Bogdanffy, MS; Mathison, BH; Taylor, ML | 1 |
| de Groot, AJ; Jansen, JG; Tates, AD; van Teijlingen, CM; van Zeeland, AA; Vrieling, H | 1 |
| Aquilina, G; Bignami, M | 1 |
| Gerson, SL; Liu, L; Markowitz, S | 1 |
| Adamiak, RW; Biala, E; Milecki, J; Popenda, M | 1 |
| Aquilina, G; Bignami, M; Ceccotti, S; Hampson, R; Martinelli, S | 1 |
| Hoogeveen, AT; Oostra, BA | 1 |
| Berger, MS; Blank, A; Bobola, MS; Silber, JR; Tseng, SH | 1 |
| Kyrtopoulos, SA | 1 |
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| Awai, T; Bessho, Y; Hori, H; Kimura, S; Nishikawa, K; Ochi, A; Ohno, S; Suzuki, T; Tomikawa, C; Yokogawa, T; Yokoyama, S | 1 |
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| Beland, FA; Bodnar, W; Koturbash, I; Pardo-Manuel Devillena, F; Pogribny, IP; Rusyn, I; Scherhag, A; Sexton, K; Sorrentino, J; Swenberg, JA | 1 |
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| Jones, R; Matter, B; Ming, X; Shanley, R; Song, M; Tretyakova, N; Veliath, E | 1 |
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| Goto-Ito, S; Hou, YM; Ito, T; Masuda, I; Sekine, S; Suh, SW; Yokoyama, S; Yoshida, K | 1 |
| Amin, SG; Belinsky, SA; Collins, LB; Crowell, RE; Desai, D; Gilliland, FD; Jauregui, AR; Juri, DE; Leng, S; Lin, Y; Liu, Y; Picchi, MA; Stidley, CA; Swenberg, JA; Tellez, CS; Thomas, CL; Wathelet, MG; Wu, G; Zhang, X | 1 |
| Kimura, S; Sato, Y; Shoji, T; Suzuki, T; Takaya, A; Yamamoto, T | 1 |
| Bender, S; Ehrenhofer-Murray, AE; Hartmann, M; Helm, M; Katze, JR; Lyko, F; Müller, M; Nellen, W; Schuster, I; Thüring, KL | 1 |
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| Challand, MR; Chin, JW; Ganzinger, KA; Horrocks, MH; Klenerman, D; Lewis, BW; Ranasinghe, RT; Schmied, WH; Shivji, N; Softley, C; Spencer, J | 1 |
| Bagryanskaya, EG; Endutkin, AV; Grin, IR; Gruber, DR; Johnson, EC; Kiryutin, AS; Kupryushkin, MS; Lomzov, AA; Miears, HL; Okon, M; Petrova, DV; Shernyukov, AV; Smirnov, SL; Toner, JJ; Yurkovskaya, AV; Zharkov, DO | 1 |
| Fan, YC; Qian, Y; Wang, JW; Wang, K; Wu, CS; Zhang, J; Zhao, Q | 1 |
| Atlasi, Y; Ehrenhofer-Murray, AE; Kelly, VP; Legrand, C; Lyko, F; Müller, M; Tuorto, F | 1 |
| Antunes, AMM; Beland, FA; Churchwell, MI; de Conti, A; Pogribny, IP; Tryndyak, V; VonTungeln, LS | 1 |
| Hartwig, B; Hümann, U; Jiao, WB; Kiefer, C; Koch, MA; Piednoël, M; Schneeberger, K; Sun, H; Willing, EM | 1 |
| Aiba, Y; Hibino, M; Shoji, O | 1 |
| Ali, AT; Hodgkinson, A; Idaghdour, Y | 1 |
| Cai, H; Gao, Y; Gu, H; Gu, J; Li, A; Li, J; Lu, M; Lu, Y; Ma, Y; Zhou, J | 1 |
| Ghaem Maghami, M; Höbartner, C; Lenz, AK; Scheitl, CPM | 1 |
| Ankri, S; Begley, TJ; Cai, MW; Coppée, JY; Dedon, PC; Gourinath, S; Guillen, N; Hisaeda, H; Legendre, R; Mazumdar, M; Nagaraja, S; Saito-Nakano, Y; Sarid, L; Shaulov, Y; Shimokawa, C; Sun, J; Trebicz-Geffen, M; Varet, H | 1 |
| Kagra, D; Kumar, NVS; Mahmi, AS; Prabhakar, PS; Sharma, P | 1 |
| Cao, L; Chen, Y; Ebert, N; Gorbalenya, AE; Guo, D; Kindler, E; Liu, Q; Pan, R; Perlman, S; Sun, Y; Thiel, V; Zhang, Z; Zhou, Y; Züst, R | 1 |
| Hirata, A; Hori, H; Kakizono, R; Kawai, K; Namba, M; Nishida, Y; Ohmori, S; Okada, K; Yamagami, R | 1 |
| Cao, D; Huang, W; Su, Y; Xing, Z; Yang, X; Zhou, X | 1 |
| Muthmann, N; Rau, K; Reichert, D; Rentmeister, A; Rösner, L | 1 |
13 review(s) available for isomethyleugenol and guanine
| Article | Year |
|---|---|
Self-destruction and tolerance in resistance of mammalian cells to alkylation damage.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; DNA Damage; Drug Tolerance; Gene Expression Regulation, Neoplastic; Guanine; HeLa Cells; Humans; Methylation; Methyltransferases; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase | 1992 |
5'-terminal cap structure in eucaryotic messenger ribonucleic acids.
Topics: Chemical Phenomena; Chemistry; Guanine; Insect Viruses; Methylation; Methyltransferases; Nucleotidyltransferases; Orthomyxoviridae; Phosphates; Protein Biosynthesis; Reoviridae; Ribosomes; RNA Cap Analogs; RNA Caps; RNA Nucleotidyltransferases; RNA, Messenger; RNA, Viral; Templates, Genetic; Vaccinia virus; Vesicular stomatitis Indiana virus | 1980 |
Enzymes involved in the repair of damaged DNA.
Topics: Adenine; Animals; Base Composition; Chemical Phenomena; Chemistry; Deoxyribonuclease IV (Phage T4-Induced); Deoxyribonucleases; Deoxyribonucleotides; DNA; DNA Glycosylases; DNA Replication; DNA Transposable Elements; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Directed DNA Polymerase; Endonucleases; Escherichia coli; Escherichia coli Proteins; Exonucleases; Guanine; Humans; Methylation; Mutation; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ribonucleotide Reductases; Substrate Specificity; Transcription, Genetic; Ultraviolet Rays; Uracil-DNA Glycosidase | 1981 |
Toxicity-induced aberrant methylation of DNA and its repair.
Topics: Alkylation; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; DNA; DNA Repair; Formaldehyde; Guanine; Hydrazines; Methylation; Methylhydrazines; S-Adenosylmethionine | 1984 |
DNA damage tolerance, mismatch repair and genome instability.
Topics: Animals; Bacterial Proteins; Base Sequence; CHO Cells; Colonic Neoplasms; Cricetinae; DNA Damage; DNA Repair; DNA, Satellite; Escherichia coli; Female; Fungal Proteins; Genome; Guanine; Humans; Male; Mammals; Methylation; Methyltransferases; Molecular Sequence Data; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Saccharomyces cerevisiae; Sister Chromatid Exchange | 1994 |
DNA repair.
Topics: Animals; Cockayne Syndrome; DNA; DNA Repair; Guanine; Humans; Methylation; Xeroderma Pigmentosum | 1993 |
Genetic instability and methylation tolerance in colon cancer.
Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Damage; DNA Repair; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; O(6)-Methylguanine-DNA Methyltransferase; Phenotype | 1996 |
Animal model for fragile X syndrome.
Topics: Animals; Carrier Proteins; Codon; Cytosine; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Guanine; Humans; Intellectual Disability; Methylation; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Biosynthesis; Repetitive Sequences, Nucleic Acid; RNA-Binding Proteins; RNA, Messenger | 1997 |
[Repair of alkylated DNA and consequences of its failure].
Topics: Alkylating Agents; Animals; Base Pair Mismatch; Cloning, Molecular; DNA Damage; DNA Repair; Gene Deletion; Guanine; Humans; Methylation; Mutation; O(6)-Methylguanine-DNA Methyltransferase | 2001 |
BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis.
Topics: Alkylation; Animals; Apoptosis; Base Pair Mismatch; Carbon-Oxygen Lyases; CHO Cells; Cricetinae; Cricetulus; Deoxyribonuclease IV (Phage T4-Induced); DNA Adducts; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Guanine; Humans; Mammals; Methylation; Mice; Mice, Knockout; Mutagenesis; Mutagens; N-Glycosyl Hydrolases; O(6)-Methylguanine-DNA Methyltransferase; Oxidants; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Transfection | 2001 |
Preparation of DNA-protein complexes suitable for spectroscopic analysis.
Topics: Aldehydes; Cross-Linking Reagents; DNA; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Guanine; Lysine; Macromolecular Substances; Methylation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleoproteins; Oxidation-Reduction; Photochemistry; Plant Proteins; Protein Conformation; Ribosome Inactivating Proteins, Type 2; Schiff Bases; Spectrometry, Fluorescence | 2003 |
Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.
Topics: Alkylating Agents; Animals; Animals, Genetically Modified; Apoptosis; Base Pair Mismatch; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; Cricetulus; DNA; DNA Damage; DNA Repair; DNA Replication; Fibroblasts; Guanine; Guanosine; Humans; Methylation; Mice; Models, Genetic; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Recombination, Genetic; Sister Chromatid Exchange | 2004 |
Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA; DNA Repair; Epigenesis, Genetic; Estrogens; Guanine; Histones; Humans; Methylation; Oxidation-Reduction; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc | 2013 |
452 other study(ies) available for isomethyleugenol and guanine
| Article | Year |
|---|---|
High-resolution liquid chromatographic analysis of methylated purine and pyrimidine bases in transfer RNA.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Liquid; Cytosine; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Liver; Methylation; Neoplasms; Rats; RNA, Transfer | 1976 |
Kinetics and mechanism of carbon-8 methylation of purine bases and nucleosides by methyl radical.
Topics: Adenine; Adenosine; Caffeine; Guanine; Guanosine; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Methods; Methylation; Photochemistry; Purine Nucleosides | 1977 |
The methylated purines of Tetrahymena pyriformis transfer ribonucleic acid.
Topics: Adenine; Animals; Chromatography; Guanine; Methylation; Purines; RNA, Transfer; Tetrahymena pyriformis | 1979 |
Metabolism of nitrosamines in vivo. V Investigation on 14CO2 exhalation, liver RNA labelling and isolation of two metabolites from urine after administration of [2, 5-14C-]dinitrosopiperazine to rats.
Topics: Animals; Bile; Guanine; Liver; Methylation; Nitrosamines; Nitroso Compounds; Oxidation-Reduction; Piperazines; Pyrrolidines; Rats; RNA | 1976 |
New class of ribonucleic acid in Neurospora associated with the outer cell envelope.
Topics: Adenine; Cell Membrane; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Methylation; Molecular Weight; Neurospora; Neurospora crassa; Nucleic Acid Denaturation; RNA; Uracil | 1977 |
5' Cap methylation of homologous poly A(+) RNA by a RNA (guanine-7) methyltransferase from Neurospora crassa.
Topics: Guanine; Methylation; Methyltransferases; Neurospora; Neurospora crassa; Poly A; Reoviridae; Ribonucleases; RNA; RNA, Messenger; RNA, Viral | 1978 |
Repair of O6-methylguanine in adapted Escherichia coli.
Topics: Adaptation, Physiological; DNA Repair; DNA, Bacterial; Guanine; Methylation; Methylnitronitrosoguanidine; Mutation; Structure-Activity Relationship | 1978 |
Reaction of nucleosome DNA with dimethyl sulfate.
Topics: Adenine; Animals; Chromatin; DNA; Guanine; Male; Methylation; Nucleic Acid Conformation; Sulfuric Acid Esters | 1979 |
Transmethylation and transguanylylation in 5'-RNA capping system isolated from rat liver nuclei.
Topics: Animals; Cell Nucleus; Guanine; Kinetics; Liver; Male; Methylation; Methyltransferases; Rats; RNA Caps; RNA, Messenger | 1979 |
[Some peculiarities of phage DDVI-specific methylases].
Topics: Adenine Nucleotides; Coliphages; DNA, Viral; Drug Stability; Enzyme Repression; Escherichia coli; Guanine; Methylation; Methyltransferases; Purines; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
A study of unwinding of DNA and shielding of the DNA grooves by RNA polymerase by using methylation with dimethylsulphate.
Topics: Adenine; Binding Sites; Coliphages; DNA-Directed RNA Polymerases; DNA, Viral; Escherichia coli; Guanine; Methane; Methylation; Oligodeoxyribonucleotides; Poly dA-dT; Sulfuric Acids; Uridine Monophosphate | 1978 |
DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by O(6)-methylguanine.
Topics: Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA Polymerase I; Escherichia coli; Genetic Code; Guanine; Methylation; Methylnitrosourea; Polydeoxyribonucleotides; Sulfuric Acid Esters; Templates, Genetic; Thymidine Monophosphate | 1979 |
Circular dichroism anisotrophy of DNA with different modifications at N7 of guanine.
Topics: Animals; Cattle; Circular Dichroism; Copper; DNA; DNA, Bacterial; Escherichia coli; Guanine; Ligands; Methylation; Nucleic Acid Conformation; Silver; Thymus Gland | 1979 |
Distribution of O6-methylguanine in rat DNA following pretreatment in vivo with methylnitrosourea.
Topics: Animals; Brain; DNA; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats | 1979 |
O6-methylguanine accumulates in DNA of mammary glands after administration of N-methyl-N-nitrosourea to rats.
Topics: Animals; Brain; DNA; DNA Repair; Female; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats; Urinary Bladder | 1979 |
Rapid determination of methylated purines in DNA treated with N-methyl-N-nitrosourea using high-performance liquid chromatography.
Topics: Adenine; Chromatography, High Pressure Liquid; DNA; Guanine; Methylation; Methylnitrosourea; Nitrosourea Compounds | 1979 |
Mechanism of perinatal tumor induction by neuro-oncogenic alkylnitrosoureas and dialkylaryltriazenes.
Topics: Animals; Brain; DNA; DNA Repair; Female; Fetus; Guanine; Liver; Maternal-Fetal Exchange; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Pregnancy; Rats; Triazenes | 1979 |
Synthesis and reactions of 7,8-dihydro-8-methylpterin and 9-methylguanine 7-oxide.
Topics: Chemical Phenomena; Chemistry; Guanine; Hydroxylation; Methods; Methylation; Pterins | 1977 |
The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. II. The GC-rich region.
Topics: Animals; Base Sequence; Cytosine; DNA; Female; Genes; Guanine; Methylation; Oocytes; Ovum; RNA, Ribosomal; Xenopus | 1978 |
Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis.
Topics: Animals; Base Sequence; Cells; Cytosine; DNA; DNA Restriction Enzymes; Eukaryotic Cells; Guanine; Methylation; Ribosomes; Xenopus | 1978 |
Use of restriction enzymes to study eukaryotic DNA methylation: II. The symmetry of methylated sites supports semi-conservative copying of the methylation pattern.
Topics: Animals; Base Sequence; Cells; Cytosine; DNA; DNA Restriction Enzymes; Eukaryotic Cells; Guanine; Methylation; Models, Chemical; Ribosomes; Xenopus | 1978 |
Removal of methylated purines from rat liver DNA after administration of dimethylnitrosamine.
Topics: Adenine; Animals; Chromatin; Deoxyribonucleases; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Female; Guanine; Liver; Methylation; Nitrosamines; Rats | 1978 |
Dimethylnitrosamine inhibits enzymatic removal of O6-methylguanine from DNA.
Topics: Animals; Cattle; Depression, Chemical; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Methylation; Nitrosamines; Rats | 1978 |
DNA alkylation and neuro-oncogenesis by 3,3-dimethyl-1-phenyltriazene.
Topics: Alkylating Agents; Animals; Brain Chemistry; Carbon Radioisotopes; DNA; Female; Guanine; Liver; Male; Maternal-Fetal Exchange; Methylation; Pregnancy; Purines; Rats | 1978 |
Effect of pretreatment with other dialkylnitrosamines on excision from hepatic DNA of O6-methylguanine produced by dimethylnitrosamine.
Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; Guanine; Liver; Methylation; Nitrosamines; Rats; Time Factors | 1978 |
Distribution of 7-methylguanine and of replication sites in the different kinetic classes of DNA from rats treated with dimethylnitrosamine.
Topics: Animals; Base Sequence; Chromatin; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Guanine; Kinetics; Liver; Male; Methylation; Nitrosamines; Nucleic Acid Renaturation; Rats | 1978 |
Effect of hypophysectomy on persistence of methylated purines in rat liver deoxyribonucleic acid after administration of dimethylnitrosamine.
Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Female; Growth Hormone; Guanine; Hypophysectomy; Liver; Methylation; Nitrosamines; Rats | 1978 |
Formation and loss of alkylated purines from DNA of hamster liver after administration of dimethylnitrosamine.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Liver; Male; Mesocricetus; Methylation; Methyltransferases; Nitrosamines | 1979 |
1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram.
Topics: Adenine; Animals; Colon; Dimethylhydrazines; Disulfiram; DNA; Female; Guanine; Methylation; Methylhydrazines; Organ Specificity; Rats | 1979 |
Selective methylation: an incorrect hypothesis.
Topics: Cell-Free System; Escherichia coli; Guanine; Methionine; Methylation; Mutation; N-Glycosyl Hydrolases; RNA, Bacterial; RNA, Transfer; S-Adenosylhomocysteine; tRNA Methyltransferases; Uracil | 1976 |
Time dependence of ethionine-induced changes in rat liver transfer RNA methylation.
Topics: Adenine; Animals; Cytosine; Drug Interactions; Ethionine; Female; Guanine; Liver; Methylation; Rats; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases; Uracil | 1977 |
Rapid, quantitative separation by high-performance liquid chromatography of methylated bases in transfer RNA.
Topics: Adenine; Buffers; Chromatography, High Pressure Liquid; Cytosine; Guanine; Methylation; RNA, Transfer; Temperature; Time Factors; Uracil | 1977 |
Metabolism of dimethylnitrosamine and 1,2-dimethylhydrazine in cultured human bronchi.
Topics: Biotransformation; Bronchi; Culture Techniques; Dimethylhydrazines; Dimethylnitrosamine; DNA; Guanine; Humans; Hydrazines; Methylation; Mutation; Nitrosamines; Protein Binding | 1977 |
Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine.
Topics: Animals; Colon; Dimethylhydrazines; DNA; Guanine; Hydrazines; Liver; Male; Methylation; Organ Specificity; Rats | 1977 |
In vivo alkylation studies with dichlorvos at practical use concentrations.
Topics: Alkylating Agents; Animals; Chromatography, Paper; Dichlorvos; DNA; Guanine; Hydrolysis; Male; Mass Spectrometry; Methylation; Proteins; Purines; Rats; RNA | 1977 |
[Ionization potentials of nucleic acid nitrogenous bases].
Topics: Adenine; Cytosine; Guanine; Ions; Methylation; Thymine; Uracil | 1976 |
Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA.
Topics: Animals; Carcinogens; DNA; Female; Guanine; Kidney; Liver; Methylation; Nitrosamines; Rats | 1975 |
Methylation of DNA in various organs of C57B1 mice by a carcinogenic dose of N-methyl-N-nitrosourea and stabiltty of some methylation products up to 18 hours.
Topics: Adenine; Animals; Bone Marrow; Carbon Radioisotopes; Chromatography, Affinity; Chromatography, Paper; DNA; Female; Guanine; Injections, Intraperitoneal; Intestine, Small; Kidney; Liver; Lung; Methylation; Methylnitrosourea; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Spleen; Thymus Gland; Time Factors; Tritium | 1975 |
Role of apurinic sites in the resistance of methylated oligodeoxyribonucleotides to degradation by spleen exonuclease.
Topics: Adenine; Binding Sites; Binding, Competitive; Chromatography, Gel; Chromatography, Paper; DNA; Exonucleases; Guanine; Kinetics; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Spleen; Time Factors | 1975 |
Transfer of the methyl group of methionine to choline and to tRNA in the honeybee Apis mellifica L.
Topics: Animals; Bees; Choline; Cytosine; Fatty Acids; Guanine; Lipids; Methylation; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 1975 |
Unconventional nucleotide analogues. Part XIII. (2S,4S)-2-hydroxymethyl- and 2-carboxy-4-(purin-9-yl)pyrrolidines.
Topics: Adenine; Antineoplastic Agents; Guanine; Hydroxylation; Hypoxanthines; Methylation; Proline; Purine Nucleosides; Pyrrolidines | 1975 |
Interaction of the carcinogen 3,3-dimethyl-1-phenyltriazene with nucleic acids of various rat tissues and the effect of a protein-free diet.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Dietary Proteins; DNA; Female; Guanine; Kidney; Liver; Methylation; Rats; RNA; Triazenes | 1976 |
Dioxin- and Ah receptor-dependent protein binding to xenobiotic responsive elements and G-rich DNA studied by in vivo footprinting.
Topics: Animals; Base Sequence; Cell Line; DNA; DNA Fingerprinting; DNA-Binding Proteins; Guanine; Methylation; Mice; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Xenobiotics | 1992 |
Reaction of O6-alkylguanine-DNA alkyltransferase with O6-methylguanine analogues: evidence that the oxygen of O6-methylguanine is protonated by the protein to effect methyl transfer.
Topics: Escherichia coli; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oxygen; Protons | 1992 |
MyoD binds to the guanine tetrad nucleic acid structure.
Topics: Animals; Base Sequence; Creatine Kinase; DNA Probes; DNA-Binding Proteins; Enhancer Elements, Genetic; Guanine; Methylation; Molecular Sequence Data; Muscle Proteins; MyoD Protein; Nucleic Acid Conformation; Recombinant Proteins; Substrate Specificity; Tetrahymena | 1992 |
Interaction of the Bacillus subtilis glnRA repressor with operator and promoter sequences in vivo.
Topics: Bacillus subtilis; Base Sequence; Binding Sites; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Glutamate-Ammonia Ligase; Guanine; Methylation; Molecular Sequence Data; Operator Regions, Genetic; Potassium Permanganate; Promoter Regions, Genetic; Pyrimidines; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Sulfuric Acid Esters | 1992 |
Expression and CpG methylation of the insulin-like growth factor II gene in human smooth muscle tumors.
Topics: Base Sequence; Blotting, Southern; Cytosine; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Guanine; Humans; Insulin-Like Growth Factor II; Leiomyoma; Leiomyosarcoma; Methylation; Molecular Sequence Data; Muscle, Smooth; Polymorphism, Restriction Fragment Length; RNA, Messenger; Uterus | 1992 |
Choice of enzymes for mapping based on CpG islands in the human genome.
Topics: Base Composition; Base Sequence; Cytosine; Databases, Factual; DNA Restriction Enzymes; Genome, Human; Guanine; Humans; Methylation; Polymorphism, Restriction Fragment Length; Probability; Restriction Mapping; Substrate Specificity | 1992 |
Levels of direct-acting mutagens, total N-nitroso compounds in nitrosated fermented fish products, consumed in a high-risk area for gastric cancer in southern China.
Topics: China; Chromatography, High Pressure Liquid; Fermentation; Fish Products; Guanine; Herpesvirus 4, Human; Humans; Hydrogen-Ion Concentration; Methylation; Mutagenicity Tests; Mutagens; Nitrosation; Nitroso Compounds; Risk Factors; SOS Response, Genetics; Stomach Neoplasms | 1992 |
Epigenetic silencing of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in Mex- human cells.
Topics: Cytosine; DNA; DNA Repair; Gene Expression; Gene Expression Regulation, Enzymologic; Guanine; Humans; Lymphocytes; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Phenotype | 1992 |
Purines. LII. Synthesis and biological evaluation of 8-methylguanine 7-oxide and its 9-arylmethyl derivatives.
Topics: Animals; Antibiotics, Antineoplastic; Guanine; Methylation; Mice; Purines | 1992 |
Lack of correlation between DNA methylation and hepatocarcinogenesis in rats and hamsters treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Carcinogens; Cells, Cultured; Cricetinae; DNA; Guanine; Liver; Liver Neoplasms; Male; Mesocricetus; Methylation; Methyltransferases; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344 | 1992 |
The FLP protein contacts both major and minor grooves of its recognition target sequence.
Topics: 4-Hydroxyaminoquinoline-1-oxide; Base Sequence; Binding Sites; DNA Nucleotidyltransferases; DNA, Fungal; DNA, Single-Stranded; Fungal Proteins; Guanine; Methylation; Molecular Sequence Data; Potassium Permanganate; Restriction Mapping; Saccharomyces cerevisiae; Substrate Specificity; Sulfuric Acid Esters; Thymine | 1992 |
Sequence specificity of DNA repair by Escherichia coli Fpg protein.
Topics: Base Sequence; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; N-Glycosyl Hydrolases; Oligonucleotide Probes | 1992 |
In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
Topics: Adenine; Animals; Base Sequence; Binding Sites; Cell Line; DNA; DNA Fingerprinting; DNA-Binding Proteins; Globins; Guanine; Humans; Hybrid Cells; Methylation; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid | 1992 |
Nucleic acid specificity of a vertebrate telomere-binding protein: evidence for G-G base pair recognition at the core-binding site.
Topics: Animals; Base Composition; Base Sequence; Binding Sites; Chick Embryo; DNA-Binding Proteins; Guanine; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid; Telomere | 1992 |
Alkylation of rodent tissue DNA induced by N-nitrosobis(2-hydroxypropyl)amine.
Topics: Alkylation; Animals; Carcinogens; Cricetinae; DNA; Dose-Response Relationship, Drug; Guanine; Kidney; Liver; Lung; Mesocricetus; Methylation; Nitrosamines; Pancreas; Rats; Rats, Inbred Strains; Species Specificity | 1992 |
Formation and repair of O6-methylguanine and methylation of the Ha-ras proto-oncogene by N-methyl-N-nitrosourea are not associated with mammary tumor resistance in the Copenhagen rat.
Topics: Animals; Blotting, Northern; Blotting, Southern; DNA Repair; DNA, Neoplasm; Drug Resistance; Female; Genes, ras; Guanine; Mammary Neoplasms, Experimental; Methylation; Methylnitrosourea; Rats | 1992 |
Biological properties of imidazole ring-opened N7-methylguanine in M13mp18 phage DNA.
Topics: Alkylating Agents; Base Sequence; beta-Galactosidase; Coliphages; DNA Damage; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Guanine; Imidazoles; Methylation; Molecular Sequence Data; Mutagenesis; Pyrimidines; Sulfuric Acid Esters; Transfection | 1992 |
Preferential methylation of the Ha-ras proto-oncogene by methylnitrosourea in rat mammary glands.
Topics: Animals; Blotting, Northern; Blotting, Southern; DNA; Female; Genes, ras; Guanine; Mammary Glands, Animal; Methylation; Methylnitrosourea; Rats; Rats, Inbred BUF; Restriction Mapping; RNA; Transcription, Genetic | 1991 |
Novel DNA superstructures formed by telomere-like oligomers.
Topics: Base Sequence; Cations; DNA; Guanine; Methylation; Models, Molecular; Molecular Sequence Data; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Sensitivity and Specificity; Telomere | 1992 |
Retinoblastoma susceptibility genes contain 5' sequences with a high propensity to form guanine-tetrad structures.
Topics: Amino Acid Sequence; Animals; Base Sequence; Genes, Retinoblastoma; Guanine; Humans; Macromolecular Substances; Methylation; Mice; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Single-Strand Specific DNA and RNA Endonucleases; Sodium | 1992 |
Chlamydomonas reinhardtii telomere repeats form unstable structures involving guanine-guanine base pairs.
Topics: Animals; Base Composition; Base Sequence; Chlamydomonas reinhardtii; Guanine; Macromolecular Substances; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Potassium; Repetitive Sequences, Nucleic Acid; Sodium; Telomere | 1992 |
The effects of Chinese tea on the methylation of DNA by the esophageal carcinogen N-nitrosomethylbenzylamine.
Topics: Animals; Anticarcinogenic Agents; Autoradiography; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Guanine; Male; Methylation; Purine Nucleotides; Rats; Rats, Inbred Strains; Tea | 1991 |
Guanine-06 methylation reduces the reactivity of d(GpG) towards platinum complexes.
Topics: Binding, Competitive; Cisplatin; Deoxyguanine Nucleotides; DNA; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Nucleic Acid Conformation; Platinum; Structure-Activity Relationship | 1991 |
A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methylt
Topics: 5-Methylcytosine; Cytosine; Escherichia coli; Guanine; Kinetics; Methylation; Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Ribosomal Proteins; Ribosomes; RNA, Ribosomal, 16S; Substrate Specificity | 1991 |
Identification of 7-(2-hydroxyethyl)guanine as a product of alkylation of calf thymus DNA with clomesone.
Topics: Alkylation; Animals; Antineoplastic Agents; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrolysis; Mesylates; Methylation; Thymus Gland | 1991 |
Beta-deuteration of N-nitrosoethylmethylamine causes a shift in DNA methylation from rat liver to esophagus.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Chromatography; Deuterium; Dimethylnitrosamine; DNA; Esophagus; Guanine; Kidney; Liver; Lung; Male; Methylation; Microsomes, Liver; Nitrosamines; Rats; Rats, Inbred F344 | 1991 |
O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Guanine; Hydroxylation; Lung Neoplasms; Methylation; Mice; Nitrosamines | 1991 |
Immunocytochemical localization of DNA adducts induced by a single dose of N-nitroso-N-methylbenzylamine in target and non-target tissues of tumor formation in the rat.
Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA Repair; DNA, Neoplasm; Guanine; Immunohistochemistry; Male; Methylation; Organ Specificity; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
CpG islands: features and distribution in the genomes of vertebrates.
Topics: Animals; Base Composition; Base Sequence; Centrifugation, Density Gradient; Chickens; Cytosine; Dinucleoside Phosphates; Genome; Guanine; Humans; Methylation; Mice; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Vertebrates | 1991 |
Immunocytochemical analysis of carcinogen-DNA adducts in normal and preneoplastic tissues.
Topics: Animals; Biotransformation; Carcinogens; DNA; DNA, Neoplasm; Guanine; Immunohistochemistry; Liver Neoplasms, Experimental; Methylation; Nasal Cavity; Precancerous Conditions; Rats | 1991 |
32P-postlabeling of 7-methylguanine adducts in DNA.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Methylation; Phosphorylation; Polynucleotide 5'-Hydroxyl-Kinase | 1990 |
Enzymatic methylation of cytosine in DNA is prevented by adjacent O6-methylguanine residues.
Topics: Base Sequence; Cytosine; DNA-Cytosine Methylases; DNA, Bacterial; Guanine; Methylation; Micrococcus; Molecular Sequence Data | 1991 |
Non-methylated islands in fish genomes are GC-poor.
Topics: Actins; Animals; Base Sequence; Blotting, Southern; Cytosine; Dinucleoside Phosphates; DNA; Drosophila; Fishes; Guanine; Humans; Metallothionein; Methylation; Molecular Sequence Data; Rats | 1991 |
Mechanism of benzylselenocyanate inhibition of azoxymethane-induced colon carcinogenesis in F344 rats.
Topics: Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Cyanates; Cytochrome P-450 Enzyme System; DNA; Drug Screening Assays, Antitumor; Guanine; Male; Methylation; Methylazoxymethanol Acetate; Microsomes, Liver; Organoselenium Compounds; Rats; Rats, Inbred F344; Selenium | 1991 |
In vivo interactions of the NahR transcriptional activator with its target sequences. Inducer-mediated changes resulting in transcription activation.
Topics: Alleles; Bacterial Proteins; Base Sequence; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Guanine; Methylation; Molecular Sequence Data; Nucleotide Mapping; Oligonucleotide Probes; Operon; Plasmids; Promoter Regions, Genetic; Restriction Mapping; Transcription Factors; Transcription, Genetic | 1991 |
The isolation of monoclonal antibodies selected for the detection of imidazole ring-opened N7-ethylguanine in purified DNA and in cells in situ. Crossreaction with methyl, 2-hydroxyethyl and sulphur mustard adducts.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; DNA; Enzyme-Linked Immunosorbent Assay; Guanine; Humans; Methylation; Mice; Mice, Inbred BALB C; Mustard Gas; Rats | 1991 |
DNA methylation in specific cells of rat liver by N-nitrosodimethylamine and N-nitrosomethylbenzylamine.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Species Specificity | 1991 |
Singlet-singlet energy transfer along the helix of a double-stranded nucleic acid at room temperature.
Topics: Animals; Cattle; DNA; Energy Transfer; Fluorescence; Guanine; Mathematics; Methylation; Models, Chemical; Stochastic Processes; Temperature | 1990 |
Methylated oxypurines and induction of differentiation of murine erythroleukemia cells.
Topics: Adenosine Diphosphate; Animals; Cell Differentiation; Dolichol Phosphates; Friend murine leukemia virus; Glycoproteins; Guanine; Leukemia, Erythroblastic, Acute; Methylation; Mice; Oligosaccharides; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured | 1990 |
DNA looping and unlooping by AraC protein.
Topics: Arabinose; AraC Transcription Factor; Bacterial Proteins; Binding Sites; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Escherichia coli Proteins; Fucose; Gene Expression Regulation, Bacterial; Guanine; Macromolecular Substances; Methylation; Mutation; Nucleic Acid Conformation; Operon; Protein Conformation; Repressor Proteins; Transcription Factors | 1990 |
Interaction of oligonucleotides containing 6-O-methylguanine with human DNA (cytosine-5-)-methyltransferase [published erratumm appears in Biochemistry 1992 Aug 4;31(30):7008].
Topics: Base Composition; Base Sequence; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Guanine; Humans; Kinetics; Methylation; Molecular Sequence Data; Nucleotide Mapping; Oligonucleotides | 1990 |
A sodium-potassium switch in the formation of four-stranded G4-DNA.
Topics: Animals; Base Sequence; Cations, Monovalent; Chromosomes; DNA; Electrophoresis; Guanine; Macromolecular Substances; Methylation; Molecular Sequence Data; Potassium; Repetitive Sequences, Nucleic Acid; Sodium; Tetrahymena | 1990 |
Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Guanine; Hyperplasia; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Metaplasia; Methylation; Microscopy, Electron; Nitrosamines; Nose Neoplasms; Olfactory Mucosa; Rats; Rats, Inbred F344 | 1990 |
Capping of U6 small nuclear RNA in vitro can be uncoupled from transcription.
Topics: Animals; Guanine; HeLa Cells; Humans; Methylation; Mice; Mutation; Phosphates; RNA Caps; RNA, Small Nuclear; T-Phages; Transcription, Genetic | 1990 |
Activation of N-nitrosobis(2-oxopropyl)amine by liver and nasal mucosa tissue from intact and castrated male rats.
Topics: Animals; Guanine; Liver; Male; Methylation; Methyltransferases; Mutagens; Mutation; Nasal Mucosa; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Orchiectomy; Rats; Rats, Inbred Strains | 1990 |
Induction of adipocyte formation in 10T1/2 cells by 1-methylguanine and 7-methylguanine.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; DNA; Guanine; Methylation; Mice; Neoplasms | 1985 |
The asymmetric methylation of CG palindromic dinucleotides increases sister-chromatid exchanges.
Topics: Aedes; Animals; Azacitidine; Base Sequence; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytosine; Dinucleoside Phosphates; Female; Guanine; Methylation; Oligonucleotides; Ovary; Sister Chromatid Exchange | 1988 |
Methylation at the CpG doublet in equine adenovirus genome.
Topics: Adenoviridae; Animals; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; Genes, Viral; Guanine; Horses; Methylation; Tumor Cells, Cultured | 1989 |
Methylation of DNA by three N-nitroso compounds: evidence for sequence specific methylation by a common intermediate.
Topics: Base Sequence; Dimethylnitrosamine; DNA; DNA Restriction Enzymes; Guanine; Methylation; Methylnitrosourea; Nitrosamines; Nitroso Compounds; Plasmids; Polydeoxyribonucleotides | 1989 |
Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype.
Topics: Alkylating Agents; Alkylation; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Guanine; Humans; Hydrazines; Methylation; Methyltransferases; Neoplasm Proteins; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Sulfones; Tumor Cells, Cultured | 1989 |
A G4-DNA/B-DNA junction at codon 12 of c-Ha-ras is actively and asymmetrically methylated by DNA(cytosine-5)methyltransferase.
Topics: Base Sequence; Codon; Cytosine; Deoxyribonucleases, Type II Site-Specific; Dimethyl Sulfoxide; DNA; DNA (Cytosine-5-)-Methyltransferases; Guanine; Humans; Methylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras) | 1989 |
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
Topics: Alkylating Agents; Amino Acids; Chromatography, High Pressure Liquid; Deoxyribonucleotides; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Guanine; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine | 1989 |
Basal-level expression of the yeast HSP82 gene requires a heat shock regulatory element.
Topics: Base Sequence; Binding, Competitive; Blotting, Northern; Gene Expression Regulation, Fungal; Guanine; Heat-Shock Proteins; Methylation; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; Saccharomyces cerevisiae; Sulfuric Acid Esters; Transcription, Genetic | 1989 |
Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter.
Topics: Bacterial Proteins; Chaperonins; Cytosine; Deoxyribonuclease I; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Heat-Shock Proteins; In Vitro Techniques; Methylation; Nucleic Acid Denaturation; Promoter Regions, Genetic; Sigma Factor; Temperature; Transcription Factors | 1989 |
DNA isolation from small tissue samples using anion-exchange HPLC.
Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; Guanine; Indicators and Reagents; Lymphocytes; Male; Methylation; Microchemistry; Nitrosamines; Organ Specificity; Rats; Rats, Inbred F344 | 1989 |
Metabolism and DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in fetal tissues of the Syrian golden hamster.
Topics: Alkylating Agents; Animals; Chromosome Aberrations; Cricetinae; Culture Techniques; DNA Damage; Female; Fetus; Guanine; Lung; Maternal-Fetal Exchange; Methylation; Nitrosamines; Placenta; Pregnancy; Trachea | 1989 |
A GC-box motif upstream of the B19 parvovirus unique promoter is important for in vitro transcription.
Topics: Base Composition; Base Sequence; Cell Nucleus; Cytosine; Deoxyribonuclease I; DNA, Viral; Genes, Regulator; Genes, Viral; Guanine; HeLa Cells; Humans; Methylation; Molecular Sequence Data; Mutation; Parvoviridae; Plasmids; Promoter Regions, Genetic; Templates, Genetic; Transcription Factors; Transcription, Genetic | 1989 |
Detection of heavy methylation in human repetitive DNA subsets by a monoclonal antibody against 5-methylcytosine.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Base Composition; Chromatography, Affinity; Cytosine; Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; DNA, Satellite; Electrophoresis, Agar Gel; Guanine; Immunoassay; Methylation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid | 1988 |
Specific binding of estrogen receptor to the estrogen response element.
Topics: Animals; Base Sequence; DNA-Binding Proteins; DNA, Recombinant; Genes, Regulator; Genetic Vectors; Guanine; Methylation; Nucleic Acid Conformation; Plasmids; Receptors, Estrogen; Receptors, Purinergic; Transfection; Vitellogenins; Xenopus laevis | 1989 |
Some mismatch repair activities in Escherichia coli.
Topics: Adenine; Bacteriophage lambda; Base Sequence; Chromosome Mapping; Cytidine; DNA Repair; Escherichia coli; Guanine; Methylation; Mutation; Phenotype; Recombination, Genetic | 1988 |
Ability of various alkylating agents to induce adaptive and SOS responses: a study with lacZ fusion.
Topics: Alkylating Agents; Bacterial Proteins; beta-Galactosidase; DNA Glycosylases; DNA Ligases; DNA Repair; Dose-Response Relationship, Drug; Enzyme Induction; Escherichia coli; Ethylnitrosourea; Genes, Bacterial; Genes, Synthetic; Guanine; Lac Operon; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; N-Glycosyl Hydrolases; Polynucleotide Ligases | 1985 |
The intracellular signal for induction of resistance to alkylating agents in E. coli.
Topics: Alkylating Agents; Bacterial Proteins; Base Sequence; Binding Sites; Cysteine; DNA Repair; DNA, Bacterial; Drug Resistance; Enzyme Activation; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Guanine; Methylation; Methyltransferases; Peptide Hydrolases; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Transcription, Genetic | 1986 |
The effects of base analogue substitutions on the cleavage by the EcoRI restriction endonuclease of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Guanine; Hydrolysis; Hypoxanthine; Hypoxanthines; Kinetics; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship; Temperature; Thymine | 1986 |
The effects of base analogue substitutions on the methylation by the EcoRI modification methylase of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Topics: Adenine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; Guanine; Kinetics; Methylation; Methyltransferases; Oligodeoxyribonucleotides; Site-Specific DNA-Methyltransferase (Adenine-Specific); Structure-Activity Relationship; Thymine | 1986 |
Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase.
Topics: Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Female; Genes; Genetic Linkage; Guanine; Humans; Male; Methylation; Phosphoglycerate Kinase; X Chromosome | 1986 |
A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cell Line; Chlorocebus aethiops; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Recombinant; DNA, Viral; Guanine; Methylation; Simian virus 40; Thymine | 1987 |
In vivo metabolism and reaction with DNA of the cytostatic agent, 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC).
Topics: Animals; Biotransformation; Carbon Dioxide; Carbon Radioisotopes; Dacarbazine; DNA; Female; Guanine; Methylation; Rats; Rats, Inbred F344 | 1986 |
Cytotoxicity, mutations and SCEs induced by methylating agents are reduced in CHO cells expressing an active mammalian O6-methylguanine-DNA methyltransferase gene.
Topics: 4-Nitroquinoline-1-oxide; Alkylation; Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; Dose-Response Relationship, Drug; Guanine; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Mutation; Ouabain; Sister Chromatid Exchange | 1987 |
7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.
Topics: Aging; Animals; Cell Nucleus; Chromatography, High Pressure Liquid; DNA; DNA, Mitochondrial; Electrochemistry; Female; Guanine; Liver; Methylation; Mitochondria; Rats; Rats, Inbred Strains | 1988 |
Selective inhibition of methylbenzylnitrosamine-induced formation of esophageal O6-methylguanine by dietary ellagic acid in rats.
Topics: Animals; Benzopyrans; Cattle; Chromatography, High Pressure Liquid; Diet; Dimethylnitrosamine; DNA; Ellagic Acid; Esophagus; Guanine; Male; Methylation; Rats; Rats, Inbred Strains | 1988 |
Lack of detectable DNA alkylation for bromhexine in man.
Topics: Administration, Oral; Alkylation; Bromhexine; Chromatography, High Pressure Liquid; DNA; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Isotope Labeling; Male; Methylation | 1988 |
Measurement of methylated DNA purines by reversed-phase high-performance liquid chromatography and fluorimetric detection.
Topics: 1,2-Dimethylhydrazine; Animals; Chromatography, High Pressure Liquid; Colon; Dimethylhydrazines; DNA; DNA Damage; Guanine; Liver; Methylation; Purines; Rats; Spectrometry, Fluorescence | 1988 |
Base sequence effects in double helical DNA. I. Potential energy estimates of local base morphology.
Topics: Base Composition; Base Sequence; Cytosine; DNA; Guanine; Hypoxanthine; Hypoxanthines; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Stereoisomerism; Thermodynamics; Thymine; Uracil | 1987 |
Repair of thymine.guanine and uracil.guanine mismatched base-pairs in bacteriophage M13mp18 DNA heteroduplexes.
Topics: Bacteriophages; Base Composition; DNA Repair; DNA, Viral; Escherichia coli; Guanine; Methylation; Nucleic Acid Heteroduplexes; Thymine; Uracil | 1987 |
Role of formaldehyde hydrazone and catalase in hydrazine-induced methylation of DNA guanine.
Topics: Amines; Animals; Catalase; DNA; Formaldehyde; Guanine; Heterocyclic Compounds; Hydrazines; Hydrazones; Magnetic Resonance Spectroscopy; Male; Methimazole; Methylation; Rats; Rats, Inbred Strains | 1988 |
Use of oligodeoxynucleotides containing O6-alkylguanine for the assay of O6-alkylguanine-DNA-alkyltransferase activity.
Topics: DNA Repair; Guanine; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides | 1988 |
Alkylation of DNA in rats by N-nitrosomethyl-(2-hydroxyethyl)amine: dose response and persistence of the alkylated lesions in vivo.
Topics: Animals; Carcinogens; DNA; Dose-Response Relationship, Drug; Female; Guanine; Male; Methylation; Nitrosamines; Rats; Rats, Inbred F344; Sex Factors; Time Factors | 1988 |
Inactivation of O6-alkylguanine-DNA alkyltransferase in the rat liver due to an intraperitoneal administration of methylated DNA.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Structure-Activity Relationship | 1988 |
Nonenzymatic sequence-specific methyl transfer to single-stranded DNA.
Topics: Base Sequence; Deoxyuracil Nucleotides; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Guanine; Methylation; Molecular Sequence Data | 1988 |
Factors regulating activation and DNA alkylation by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and nitrosodimethylamine in rat lung and isolated lung cells, and the relationship to carcinogenicity.
Topics: Alkylation; Animals; Antibodies; Benzoflavones; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Isoenzymes; Lung; Methylation; Nitrosamines; Rats | 1988 |
A theoretical study of the effect of methylation or ethylation at O6-guanine in the structure and energy of DNA double strands.
Topics: Alkylation; Base Sequence; Chemical Phenomena; Chemistry, Physical; Computer Simulation; DNA; Guanine; Hydrogen Bonding; Methylation; Molecular Conformation; Structure-Activity Relationship; Thermodynamics | 1988 |
The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells.
Topics: Alkylating Agents; Animals; Cell Line; Cloning, Molecular; Cricetinae; DNA Damage; DNA Repair; Drug Resistance; Guanine; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Organophosphates; Organophosphorus Compounds; Structure-Activity Relationship; Transfection | 1988 |
Inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA methylation by ellagic acid.
Topics: Benzopyrans; DNA; Dose-Response Relationship, Drug; Ellagic Acid; Guanine; Methylation; Methylnitrosourea; Mutation; Spermidine | 1986 |
Comparative study on the indirect methylation of liver DNA guanine by the 1-carbon pool in hepatotoxicity.
Topics: Animals; Chemical Phenomena; Chemistry; Cricetinae; DNA; Formaldehyde; Guanine; Hydrazines; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylation; Mice; Species Specificity | 1987 |
Methylation of DNA guanine via the 1-carbon pool in dimethylnitrosamine-treated rats.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA; Guanine; Liver; Male; Methylation; Radioisotope Dilution Technique; Rats; Rats, Inbred F344; Tritium | 1986 |
Guanine and adenine analogues as tools in the investigation of the mechanisms of mismatch repair in E. coli.
Topics: Adenine; Base Sequence; Codon; Coliphages; DNA Repair; Escherichia coli; Guanine; Methylation; Mutation | 1986 |
Enzymatic conversion of guanosine 3' adjacent to the anticodon of yeast tRNAPhe to N1-methylguanosine and the wye nucleoside: dependence on the anticodon sequence.
Topics: Anticodon; Base Sequence; Guanine; Guanosine; Methylation; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae | 1987 |
Excited-state properties of DNA methylated at the N-7 position of guanine and its free fluorophore at room temperature.
Topics: DNA; Guanine; Methylation; Nucleic Acid Conformation; RNA Cap Analogs; Spectrometry, Fluorescence; Structure-Activity Relationship | 1986 |
Estimation of exposure to alkylating carcinogens by the GC-MS determination of adducts to hemoglobin and nucleic acid bases in urine.
Topics: Acrylamide; Acrylamides; Alkylating Agents; Amino Acids; Animals; Carcinogens; Epoxy Compounds; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Guanine; Hemoglobins; Methylation; Rats; Rats, Inbred Strains | 1987 |
Effect of snuff and nicotine on DNA methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; DNA; Guanine; Liver; Lung; Male; Mathematics; Methylation; Mouth; Nasal Mucosa; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Tobacco, Smokeless | 1987 |
Excretion of methylated nucleic acid bases as an indicator of exposure to nitrosatable drugs.
Topics: Adenine; Animals; Female; Guanine; Methylation; Nitroso Compounds; Nucleic Acids; Rats | 1987 |
Organ specificity, metabolism and reaction with DNA of aliphatic nitrosomethylalkylamines.
Topics: Animals; Carcinogens; DNA; Dose-Response Relationship, Drug; Esophagus; Guanine; Liver; Male; Methylation; Nitrosamines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Substrate Specificity | 1987 |
Selective repair of methylated purines in regions of chromatin DNA.
Topics: Animals; Chromatin; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Male; Methylation; Purines; Rats; Rats, Inbred Strains | 1986 |
Antibodies specific for methylated DNA elicited in rabbits recognize only a single strand region of DNA containing 7-methylguanine.
Topics: Animals; Antibody Specificity; Chromatography; DNA; DNA, Single-Stranded; Female; Guanine; Hot Temperature; Hydroxyapatites; Immunization; Methylation; Rabbits; Structure-Activity Relationship | 1986 |
Methylation of DNA guanine during the course of induction of liver cancer in hamsters by hydrazine or dimethylnitrosamine.
Topics: Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Hydrazines; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylation; Tissue Distribution | 1987 |
Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Dose-Response Relationship, Drug; Female; Guanine; Mesocricetus; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Pregnancy | 1985 |
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo.
Topics: Animals; B-Lymphocytes; Base Sequence; Cell Line; Enhancer Elements, Genetic; Genes, Regulator; Guanine; Immunoglobulin Heavy Chains; Methylation; Mice; Multiple Myeloma; RNA, Messenger; Sulfuric Acid Esters | 1985 |
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats | 1986 |
DNA and protein adducts as indicators of in vivo methylation by nitrosatable drugs.
Topics: Animals; Carcinogens; Cattle; Cysteine; DNA; Female; Globins; Guanine; Methylamines; Methylation; Nitroso Compounds; Protein Binding; Rats; Rats, Inbred Strains; Thymus Gland | 1986 |
Conformation of O6-alkylguanosines: molecular mechanism of mutagenesis.
Topics: Base Composition; Guanine; Guanosine; Hydrogen Bonding; Methylation; Mutation; Nucleic Acid Conformation | 1986 |
The role of formaldehyde in hydrazine-induced methylation of liver DNA guanine.
Topics: Aldehydes; Animals; Cricetinae; Cytosol; DNA; Formaldehyde; Guanine; Hydrazines; Liver; Male; Mesocricetus; Methylation; Microsomes, Liver | 1986 |
Tetraformyltrisazine and hydrazine-induced methylation of liver DNA guanine.
Topics: Alkylating Agents; Animals; DNA; Dose-Response Relationship, Drug; Drug Combinations; Formaldehyde; Guanine; Heterocyclic Compounds; Hydrazines; Liver; Male; Methylation; Rats | 1986 |
Homologous interactions of lambda repressor and lambda Cro with the lambda operator.
Topics: Amino Acid Sequence; Base Composition; Base Sequence; DNA-Binding Proteins; Guanine; Methylation; Models, Molecular; Mutation; Operator Regions, Genetic; Repressor Proteins; Transcription Factors; Viral Proteins; Viral Regulatory and Accessory Proteins | 1986 |
Formation of O6-methylguanine in rat liver DNA by nitrosamines does not predict initiation of preneoplastic foci.
Topics: Animals; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Precancerous Conditions; Rats; Rats, Inbred Strains | 1985 |
DNA-binding assay of methyl chloride.
Topics: Animals; DNA; Female; Guanine; Hydrolysis; Kidney; Liver; Male; Methyl Chloride; Methylation; Mice; Nucleoproteins; Rats; Rats, Inbred F344; Sex Factors; Species Specificity | 1985 |
In vitro DNA methylation by methylnitrosourea in isolated copper- or silver-preloaded rat liver nuclei.
Topics: Animals; Cell Nucleus; Copper; DNA; Guanine; In Vitro Techniques; Liver; Male; Methylation; Methylnitrosourea; Rats; Rats, Inbred Strains; Silver | 1985 |
The effect of flanking sequences on the de novo methylation of C-G pairs by the human DNA methylase.
Topics: Base Composition; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Guanine; HeLa Cells; Humans; Kinetics; Methylation; Substrate Specificity | 1985 |
[Mechanism of mutagenesis using N-methyl-N'-nitro-N-nitroso-guanidine. Methylation of nucleic acids using N-trideuteriomethyl-N'-nitroso-guanidine].
Topics: Chemical Phenomena; Chemistry; Deuterium; Diazomethane; DNA; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Methylation; Mutagens; Mutation; Nitrosoguanidines | 1972 |
[Influence of S-adenosylmethionine on the methylation of the RNA by dimethylnitrosamine in vivo].
Topics: Adenine; Animals; Body Weight; Carbon Isotopes; Chromatography, Ion Exchange; Female; Guanine; Hydrochloric Acid; Hydrolysis; Injections, Intravenous; Liver; Male; Methionine; Methylation; Mice; Nitrosamines; Nucleosides; Rats; RNA; S-Adenosylmethionine; Spectrophotometry; Tritium | 1970 |
[The organotropy of alkylating activity of dimethylnitrosamine (DMNA) and nitrosomethyl urea (NMH) in vivo].
Topics: Alkylating Agents; Animals; Body Weight; Carbon Isotopes; Female; Formates; Guanine; Hepatectomy; Injections, Intravenous; Kidney; Liver; Lymphoma, Large B-Cell, Diffuse; Male; Methanol; Methylation; Mice; Muscles; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosourea Compounds; Rats; RNA; RNA, Neoplasm; Salmonidae; Sarcoma, Experimental; Urea | 1970 |
[Urinary 7-methyl guanine excretion of the rat after a single application of various carcinogens].
Topics: Animals; Benz(a)Anthracenes; Carbon Isotopes; Chromatography, Ion Exchange; Guanine; Injections, Intraperitoneal; Male; Methylation; Morpholines; Nitrosamines; Nitroso Compounds; Nucleic Acids; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Stilbenes | 1972 |
Formation of N7-methylguanine in nuclear DNA and cytoplasmic RNA in mice on continuous oral administration of dimethylnitrosamine-3H solution.
Topics: Administration, Oral; Animals; DNA; Guanine; Kidney; Liver; Lung; Male; Methylation; Mice; Nitrosamines; RNA; Time Factors; Tritium | 1973 |
Metabolism of nitrosamines in vivo. 3. On the methylation of nucleic acids by aliphatic Di-n-alkyl-nitrosamines in vivo resueting from heta-oxidation: the formation of 7-methylguanine after application of 2-oxo-propyl-propyl-nitrosamine and methyl-propyl-
Topics: Animals; Guanine; Hydrolysis; Liver; Male; Mass Spectrometry; Methods; Methylation; Nitrosamines; Nucleic Acids; Rats; Tritium | 1973 |
Metabolism of nitrosamines in vivo. II. On the methylation of nucleic acids by aliphatic di-n-alkyl-nitrosamines in vivo, caused by beta-oxydation: the increased formation of 7-methyl-guanine after application of beta-hydroxypropyl-propyl-nitrosamine comp
Topics: Animals; Binding Sites; Carbon Radioisotopes; DNA; Guanine; Hydroxylation; Liver; Male; Methylation; Nitrosamines; Nitroso Compounds; Nucleic Acids; Oxidation-Reduction; Rats; RNA | 1973 |
[Study of the effects of methylation on the behavior of DNA].
Topics: Amines; Carbon Isotopes; Chemical Phenomena; Chemistry; Chemistry, Physical; Clostridium perfringens; Cytosine Nucleotides; DNA, Bacterial; Escherichia coli; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hydroxamic Acids; Methylation; Micrococcus; Proteus; RNA, Bacterial; Serratia marcescens; Spectrum Analysis; Spermine; Sulfates; Temperature; Ultracentrifugation; Viscosity | 1969 |
Agents of modulation of the transfer RNA methylases.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Castration; Chromatography; Chromatography, Gel; Enzyme Inhibitors; Estradiol; Female; Guanine; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Methylation; Methyltransferases; Molecular Weight; Neoplasms, Experimental; Rabbits; Rats; RNA, Transfer; Swine; Transferases; Uterus | 1971 |
Criticism of the use of methylated albumin-kieselguhr chromatography for the isolation of metabolically labile DNA.
Topics: Adenine; Centrifugation, Density Gradient; Cesium; Chemical Precipitation; Chlorides; Chromatography; Cytosine; DNA; Drug Stability; Guanine; Hot Temperature; Hydrolysis; Methylation; Nucleic Acid Denaturation; Perchlorates; Plants; Ribonucleases; RNA; Serum Albumin; Silicon Dioxide; Uracil | 1971 |
Methylation of deoxyribonucleic acid during hormonal stimulation of mammary cells in vitro.
Topics: Adenine; Alkaline Phosphatase; Animals; Bromodeoxyuridine; Carbon Isotopes; Cell Differentiation; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosine; DNA; DNA Replication; Epithelial Cells; Female; Formates; Guanine; Hydrocortisone; Insulin; Kinetics; Mammary Glands, Animal; Methionine; Methylation; Mice; Organ Culture Techniques; Pancreas; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Pregnancy; Prolactin; Ribonucleases; Sheep; Sodium; Thymidine; Thymine; Tritium; Venoms | 1971 |
Methylation of nucleic acids and urinary excretion of 14 C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-dimethyl-1-triazeno)-imidazole5(4)-carboxomide.
Topics: Alkylating Agents; Amides; Animals; Azo Compounds; Brain Chemistry; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Dealkylation; Diazomethane; DNA; Guanine; Humans; Imidazoles; In Vitro Techniques; Kidney; Liver Extracts; Lung; Methylation; Microsomes, Liver; Perchlorates; Purines; Rats; RNA; RNA, Ribosomal; Spectrophotometry; Tissue Extracts | 1971 |
Specific RNA methylase associated with avian myeloblastosis virus.
Topics: Adenine; Autoradiography; Avian Leukosis Virus; Centrifugation; Chromatography; Chromatography, Ion Exchange; Cytosine Nucleotides; Freezing; Guanine; Hot Temperature; Hydrolysis; Methylation; Methyltransferases; Microscopy, Electron; RNA; RNA, Transfer; Tritium; Uracil Nucleotides | 1971 |
Enzymatic DNA modifications in isolated nuclei from developing sea urchin embryos.
Topics: Adenine; Aminohydrolases; Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Chromatography, Paper; Cytosine; Cytosine Nucleotides; DNA; Electron Transport Complex IV; Formates; Guanine; Hot Temperature; Methionine; Methylation; Methyltransferases; Proteins; S-Adenosylmethionine; Sea Urchins; Thymidine; Thymine; Tritium | 1972 |
Reaction of alkylating mutagens and carcinogens with nucleic acids: detection and estimation of a small extent of methylation at O-6 of guanine in DNA by methyl methanesulphonate in vitro.
Topics: Alkanesulfonates; Animals; Carcinogens; DNA; Guanine; Male; Methylation; Mutagens; Salmonidae; Spermatozoa | 1972 |
Separation of methylated bases of ribonucleic acid by two-dimensional thin-layer chromatography.
Topics: Adenine; Adsorption; Cellulose; Chromatography, Thin Layer; Gels; Guanine; Hydrogen-Ion Concentration; Hypoxanthines; Methylation; Purines; Pyrimidines; RNA, Transfer; Silicon Dioxide; Solvents; Thymidine | 1973 |
Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
Topics: Adenine; Adenoviridae Infections; Animals; Cell-Free System; Chromatography, Paper; Cricetinae; Escherichia coli; Guanine; Methylation; Methyltransferases; Neoplasms, Experimental; RNA, Bacterial; RNA, Transfer; Tumor Virus Infections | 1972 |
Differences in the patterns of methylation in rat liver ribosomal ribonucleic acid after reaction in vivo with methyl methanesulphonate and NN-dimethylnitrosamine.
Topics: Adenine; Alkanes; Alkylating Agents; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine; Electrophoresis, Polyacrylamide Gel; Guanine; Hydrolysis; Liver; Methylation; Nitrosamines; Phosphoric Diester Hydrolases; Rats; Ribonucleases; RNA, Ribosomal; Sulfonic Acids | 1972 |
The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine.
Topics: Adenine; Alkanesulfonates; Animals; Carbon Isotopes; Carcinogens; Chromatography, Gel; Chromatography, Ion Exchange; Dimethylamines; DNA; DNA Replication; Female; Guanine; Half-Life; Hepatectomy; Kidney; Liver; Liver Regeneration; Methylation; Nitrosamines; Rats; RNA; Spectrophotometry, Ultraviolet; Time Factors; Transcription, Genetic | 1973 |
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine | 1974 |
Patterns of excretion of methylated purines in hepatocellular carcinoma.
Topics: Adenine; Adult; Carcinoma, Hepatocellular; Chromatography, Paper; Creatine; Guanine; Humans; Hydrolysis; Liver Cirrhosis; Liver Neoplasms; Male; Methylation; Purines | 1974 |
Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.
Topics: Adenine; Adenosine; Animals; Animals, Newborn; Autoradiography; Carbon Radioisotopes; Cytidine; DNA; Female; Fetus; Gestational Age; Guanine; Guanosine; Hydrolysis; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mesylates; Methylation; Nucleic Acids; Pregnancy; Rats; Rats, Inbred Strains; RNA; Time Factors | 1974 |
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases | 1974 |
[On the mechanism of action of 1-nitroso-3-nitro-1-methylguanidine during induced mutation. II. Products of the reaction of 1-nitroso-3-nitro-1-methylguanidine with nucleic bases, nucleosides, nucleosidephosphatesmand homopolyribonucleic acids].
Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography, Thin Layer; Guanidines; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Methylation; Mutagens; Mutation; Nitroso Compounds; Nucleosides; Purines; Pyrimidines; Xanthines | 1968 |
Extreme lability of the C-8 proton: a consequence of 7-methylation of guanine residues in model compounds and in DNA and its analytical application.
Topics: Chemical Phenomena; Chemistry; Chromatography, Paper; Deuterium; DNA; DNA, Bacterial; Guanine; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methylation; Nucleic Acids; Nucleosides; Solvents; Spectrophotometry; Streptococcus pneumoniae; Thiamine; Tritium; Ultraviolet Rays; Water | 1970 |
[Ethylation of guanine-N-7 in the nucleic acids of rat embryos and liver by ethylnitrosourea].
Topics: Alkylation; Animals; Carbon Isotopes; Carcinogens; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; DNA; Embryo, Mammalian; Female; Guanine; Lethal Dose 50; Liver; Maternal-Fetal Exchange; Methylation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Pregnancy; Rats; RNA | 1971 |
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.
Topics: Adenine; Animals; Brain; Brain Neoplasms; Carcinogens; DNA; DNA Repair; Female; Guanine; Kidney; Kidney Neoplasms; Liver; Methylation; Neoplasms, Experimental; Nitrosourea Compounds; Purines; Rats | 1974 |
Preparation of some N-methyl isoquanines via 6-methyl-thio-2-oxopurines, and of 8-methylisoquanine.
Topics: Chemical Phenomena; Chemistry; Guanine; Hydrogen-Ion Concentration; Methods; Methylation; Purines; Spectrophotometry, Ultraviolet | 1974 |
The mode of action of N-methyl-N'-nitro-N-nitrosoguanidine in mutagenesis. VII. The transfer of the methyl group of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Deuterium; DNA; DNA, Bacterial; Escherichia coli; Guanidines; Guanine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Mutagens; Nitro Compounds; Nitroso Compounds; Nitrosoguanidines; Quaternary Ammonium Compounds; Thymus Gland | 1972 |
Methylation pattern of lambda deoxyribonucleic acid.
Topics: Adenine; Autoradiography; Base Sequence; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Coliphages; Cytosine; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Guanine; Methionine; Methylation; Molecular Weight; Nucleic Acid Denaturation; Nucleotides; Phosphorus Isotopes; Tritium | 1972 |
Genetics of resistance to 4-aminopyrazolo-(3,4-d)-pyrimidine in Saccharomyces cerevisiae.
Topics: Adenine; Aza Compounds; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Genes, Dominant; Genes, Recessive; Genetic Linkage; Genetics, Microbial; Guanine; Hypoxanthines; Mercaptopurine; Methylation; Purines; Pyrazoles; Pyrimidines; Saccharomyces cerevisiae; Suppression, Genetic | 1973 |
Function of N2 methylguanine in phenylalanine transfer RNA.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine | 1973 |
Alterations in structure and function of transfer ribonucleic acid on chemical methylation.
Topics: Adenine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cytosine; Guanine; Methylation; Peptide Biosynthesis; Phenylalanine; Poly U; Purines; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfuric Acids; Temperature; Transfer RNA Aminoacylation; Tritium; Viscosity | 1974 |
Formation of 7-methylguanine by dichlorvos in bacteria and mice.
Topics: Animals; Chromatography, Ion Exchange; Dichlorvos; DNA; DNA, Bacterial; Escherichia coli; Guanine; Male; Methylation; Mice; Respiration; RNA; RNA, Bacterial; Species Specificity; Time Factors; Trichlorfon; Tritium | 1974 |
Effects of methylation on the stability of nucleic acid conformations: studies at the monomer level.
Topics: Adenine; Calorimetry; Chromatography, Thin Layer; Computers; Cytosine; Deuterium; DNA; DNA, Bacterial; Escherichia coli; Fourier Analysis; Guanine; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Methylation; Models, Biological; Nitrogen Isotopes; Nucleic Acid Conformation; RNA; Temperature; Thermodynamics | 1974 |
Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels.
Topics: Adenine; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Guanine; Guanosine; Hydrolysis; Methylation; Nitrosoguanidines; Nitrosourea Compounds; Nucleic Acid Denaturation; Nucleosides; Pyrimidine Nucleotides; Rabbits; RNA; Sulfuric Acids; Uracil | 1972 |
Homologies of repetitive DNA sequences among Crustacea.
Topics: Animals; Base Sequence; Brachyura; Crustacea; Cytosine; DNA; DNA-Directed RNA Polymerases; Formamides; Guanine; Methylation; Nephropidae; Nucleic Acid Hybridization; RNA; Temperature; Tritium | 1973 |
Purine N-oxides. XLVI. Some interesting reactions of 3-acetoxy-8-methylxanthine.
Topics: Chemical Phenomena; Chemistry; Cyclic N-Oxides; Guanine; Hydrolysis; Methylation; Oxidation-Reduction; Xanthines | 1973 |
Comparative studies of the hepatocarcinogen N,N-dimethylnitrosamine in vivo: reaction sites in rat liver DNA and the significance of their relative stabilities.
Topics: Alkylation; Animals; Carbon Isotopes; Chromatography; Chromatography, Ion Exchange; Chromatography, Paper; DNA; Guanine; Hydrolysis; Liver; Male; Methylation; Nitrosamines; Rats | 1973 |
Loss of 7-methylguanine from rat liver DNA after methylation in vivo with methylmethanesulphonate or dimethylnitrosamine.
Topics: Alkylating Agents; Animals; Carbon Isotopes; Chromatography, Ion Exchange; DNA; Drug Stability; Guanine; Hydrolysis; Kinetics; Liver; Male; Methylation; Rats; RNA, Ribosomal; Time Factors | 1973 |
Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate.
Topics: Adenine; Alkylation; Animals; Brain; Brain Chemistry; Carbon Isotopes; Cytoplasm; DNA; Female; Guanine; Hydrolysis; Ileum; Kidney; Liver; Methylation; Nitrosourea Compounds; Nucleic Acids; Rats; RNA; RNA, Transfer; Sulfonic Acids | 1973 |
The properties of O 6 -methylguanine in templates for RNA polymerase.
Topics: Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Paper; Cytosine Nucleotides; DNA-Directed RNA Polymerases; Guanine; Guanine Nucleotides; Kinetics; Methylation; Mutation; Polynucleotides; Templates, Genetic; Time Factors; Uracil Nucleotides | 1973 |
Formation of 7-methylguanine in liver RNA during continuous administration of dimethylnitrosoamine.
Topics: Animals; Carcinogens; Chromatography; Guanine; Liver; Male; Methylation; Mice; Nitrosamines; Radioactivity; RNA; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
A rapid column chromatographic procedure for the assay of RNA methyltransferases.
Topics: Adenine; Chromatography, Ion Exchange; Evaluation Studies as Topic; Guanine; Methods; Methylation; Methyltransferases; RNA; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
The content of 5-methylcytosine in animal DNA: the species and tissue specificity.
Topics: Adenine; Amphibians; Animals; Anura; Birds; Brain Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Cytosine; DNA; Echinodermata; Fishes; Guanine; Kidney; Liver; Lung; Male; Methylation; Muscles; Rats; Species Specificity; Spermatozoa; Spleen; Thymine | 1973 |
[Methylation of DNA cytosine in lymphocytes of healthy subjects and in chronic lympholeukosis].
Topics: Adenine; Carbon Radioisotopes; Cytosine; DNA; DNA, Neoplasm; Guanine; Humans; Leukemia, Lymphoid; Lymphocytes; Methionine; Methylation; Thymine | 1973 |
Transfer RNA methylase and transfer RNA methylase-inhibitor activity in normal and malignant human ovarian tissue.
Topics: Animals; Carbon Radioisotopes; Female; Guanine; Humans; Methylation; Neoplasm Metastasis; Ovarian Neoplasms; Ovary; Rabbits; RNA, Transfer; tRNA Methyltransferases | 1973 |
Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea--evidence for transfer of the intact methyl group.
Topics: Adenine; Animals; Carbon Radioisotopes; Carcinogens; Chromatography; Cytidine; DNA; Guanine; Hydrolysis; Male; Methane; Methylation; Nitrosourea Compounds; Salmon; Spectrophotometry, Ultraviolet; Spermatozoa; Thymidine; Tritium | 1973 |
Effect of aminoacetonitrile on the metabolism of dimethylnitrosamine and methylation of RNA during liver carcinogenesis.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Guanine; Liver; Liver Neoplasms; Male; Methylamines; Methylation; Neoplasms, Experimental; Nitriles; Nitrosamines; Rats; RNA, Neoplasm; Time Factors | 1974 |
Rapid loss of 7-methylguanine from liver nucleic acids in mice during the initial stage of liver carcinogenesis induced by dimethylnitrosamine.
Topics: Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; DNA; Drinking Behavior; Guanine; Half-Life; Liver; Liver Neoplasms; Male; Methane; Methylation; Mice; Neoplasms, Experimental; Nitrosamines; Orotic Acid; RNA; Thymidine; Time Factors; Tritium | 1974 |
Studies on the role of stimulated epidermal DNA synthesis in the initiation of skin tumors in mice by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Acetone; Adenine; Animals; Autoradiography; Croton Oil; DNA; DNA Replication; Female; Guanine; Methylation; Mice; Neoplasms, Experimental; Nitrosoguanidines; Proteins; RNA; Skin; Skin Neoplasms; Thymidine; Tritium | 1974 |
Urinary excretion of methylated purines following inhalation of dimethyl sulphate.
Topics: Adenine; Aerosols; Animals; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Male; Methane; Methylation; Mice; Purines; Sulfuric Acids; Tritium | 1974 |
Mass spectrometric studies of the interaction of platinum complexes with nucleoside analogues.
Topics: Adenine; Binding Sites; Cytosine; Guanine; Ligands; Mass Spectrometry; Methylation; Molecular Conformation; Nucleic Acid Conformation; Platinum; Structure-Activity Relationship; Thymine; Time Factors | 1974 |
Methylation of the guanine bases of transfer RNA.
Topics: Carbon Radioisotopes; Carcinoma; Cell Line; Electrophoresis, Polyacrylamide Gel; Guanine; Guanosine; Isotope Labeling; Kinetics; Methylation; Mouth Neoplasms; RNA, Transfer; Time Factors | 1974 |
Methylation properties of mitochondrion-specific transfer RNA from cultured hamster cells.
Topics: Adenine; Adenine Nucleotides; Animals; Biological Evolution; Carbon Radioisotopes; Cell Line; Chromatography, Paper; Cricetinae; Cytosine; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Ethidium; Guanine; Kidney; Methionine; Methylation; Mitochondria; Phosphorus Radioisotopes; Ribose; RNA, Transfer; Species Specificity | 1974 |
The mechanism of alkylation of DNA by 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MIC), a metabolite of DIC (NSC-45388). Non-involvement of diazomethane.
Topics: Animals; Binding Sites; Cattle; Crystallization; Deuterium; Diazomethane; DNA; Drug Stability; Guanine; Hydrogen-Ion Concentration; Imidazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Molecular Conformation; Nucleic Acid Conformation; Phthalic Acids; Solubility; Thymus Gland; Triazenes | 1974 |
On the presence of minor bases in DNA of phages DD7 and Sd and their hosts.
Topics: Adenine; Amines; Coliphages; Cytosine; DNA, Bacterial; DNA, Viral; Escherichia coli; Guanine; Methylation; Purines; Spectrum Analysis; Thymine | 1968 |
Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae.
Topics: Adenine; Carbon Isotopes; Chemical Precipitation; Chromatography, Thin Layer; Cytosine; Escherichia coli; Guanine; Magnesium; Manganese; Methionine; Methylation; Nucleosides; Nucleotides; Ribose; RNA, Bacterial; RNA, Transfer; Saccharomyces; Thymine; Transferases | 1969 |
Studies on microbial RNA. Properties of tRNA methylases from Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Chromatography; Dialysis; Enterobacter; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Methylation; RNA Nucleotidyltransferases; RNA, Bacterial; RNA, Transfer; Saccharomyces; Species Specificity; Sulfhydryl Compounds; Transferases; Triticum; Uracil | 1969 |
Transfer RNA synthesis, methylation, and thiolation in Escherichia coli cells infected with phage T2.
Topics: Carbon Isotopes; Coliphages; DNA, Viral; Escherichia coli; Genes; Guanine; Methods; Methylation; Nucleic Acid Denaturation; RNA, Bacterial; RNA, Viral; Sulfates; Sulfur; Sulfur Isotopes; Tritium | 1970 |
Differential inhibition of bacterial tRNA methylases by S-adenosylethionine and other adenine derivatives.
Topics: Adenine; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine; Escherichia coli; Guanine; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; Transferases; Uracil | 1970 |
Synthesis and chemical properties of monomers and polymers containing 7-methylguanine and an investigation of their substrate or template properties for bacterial deoxyribonucleic acid or ribonucleic acid polymerases.
Topics: Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Clostridium; Cytosine Nucleotides; DNA; DNA Nucleotidyltransferases; DNA, Bacterial; Escherichia coli; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Imidazoles; Methylation; Micrococcus; Nucleotides; Polynucleotides; Purinones; RNA Nucleotidyltransferases; Spectrophotometry; Templates, Genetic; Thymus Gland; Tritium; Ultraviolet Rays | 1970 |
Isolation of mutants of Escherichia coli lac king 5-methyluracil in transfer ribonucleic acid or 1-methylguanine in ribosomal RNA.
Topics: Carbon Isotopes; Chromosome Mapping; Escherichia coli; Guanine; Methylation; Mutation; Recombination, Genetic; Ribosomes; RNA, Bacterial; RNA, Transfer; Uracil | 1970 |
The specificity of transfer ribonucleic acid methylases from rat liver.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Guanine; Kinetics; Liver; Methionine; Methylation; Mutation; Nucleosides; Nucleotides; Pancreas; Rats; Ribonucleases; RNA, Transfer; Transferases; Ultracentrifugation | 1968 |
Transfer RNA methylases and cancer.
Topics: Animals; Carbon Isotopes; Carcinogens; Cell Differentiation; Chromatography, Ion Exchange; Escherichia coli; Ethionine; Guanine; Humans; Kidney Neoplasms; Liver Regeneration; Methionine; Methylation; Morphogenesis; Neoplasms; Nitrosamines; Phenylalanine; Protein Biosynthesis; Rats; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Transferases | 1970 |
Fragmented E. coli methionine tRNA f as methyl acceptor for rat liver tRNA methylase: alteration of the site of methylation by the conformational change of tRNA structure resulting from fragmentation.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Escherichia coli; Formates; Guanine; Liver; Methionine; Methylation; Methyltransferases; Nucleosides; Nucleotidyltransferases; Pancreas; Paper; Polynucleotides; Rats; Ribonucleases; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Transferases | 1971 |
Mutants of T2gt with altered DNA methylase activity: relation to restriction by prophage P1.
Topics: Adenine; Bacteriophages; Carbon Isotopes; Cell-Free System; Chromosome Mapping; Coliphages; Crosses, Genetic; DNA; DNA, Bacterial; DNA, Viral; Escherichia coli; Filtration; Genetics, Microbial; Glucosyltransferases; Guanine; Methylation; Methyltransferases; Micrococcus; Mutation; Recombination, Genetic; Shigella dysenteriae; Trichloroacetic Acid; Tritium | 1971 |
Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenine; Carcinogens; Chromatography, Paper; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Guanidines; Guanine; Methylation; Mutation; Nitro Compounds; Nitroso Compounds; Nitrosoguanidines; Tritium | 1970 |
Comparative studies on alkylation of bacterial DNA in vivo and in vitro.
Topics: Alkylating Agents; Alkylation; Bacillus subtilis; Chromatography, DEAE-Cellulose; DNA, Bacterial; Guanine; Methylation; Mutation; Transformation, Genetic | 1970 |
Comparison of Bacillus cereus bacteriophages CP-51 and CP-53.
Topics: Adsorption; Animals; Bacillus cereus; Bacteriophages; Centrifugation, Density Gradient; Cesium; Chlorides; Chromatography, Paper; Cytosine; Deoxyribonucleases; DNA, Viral; Formates; Guanine; Hot Temperature; Hydrolysis; Immune Sera; Lysogeny; Methylation; Microscopy, Electron; Molecular Weight; Mutation; Nucleic Acid Denaturation; Rabbits; Species Specificity; Transduction, Genetic; Ultraviolet Rays; Uracil | 1971 |
[Polarographic study of chemically methylated deoxyribonucleic acid].
Topics: DNA, Bacterial; Electrolysis; Guanine; Methylation; Micrococcus; Oxidation-Reduction; Polarography; Spectrum Analysis; Ultraviolet Rays | 1971 |
The isolation and DNA-RNA hybridization of messenger RNA for globin.
Topics: Adenine; Animals; Centrifugation, Density Gradient; Centrifugation, Zonal; Cytosine; Edetic Acid; Electrophoresis, Disc; Genetic Code; Globins; Guanine; Methylation; Mice; Molecular Weight; Nucleic Acid Hybridization; Nucleoproteins; Rabbits; Reticulocytes; RNA, Messenger; RNA, Ribosomal; Sucrose; Time Factors; Uracil | 1971 |
Effects of feeding the carcinogen dimethylnitrosamine on its metabolism and methylation of DNA in the mouse.
Topics: Animals; Carbon Isotopes; Carcinogens; Chromatography, Gas; Depression, Chemical; DNA; Guanine; Kidney; Liver; Lung; Male; Methylation; Mice; Microsomes, Liver; Nitrosamines; Oxidoreductases; Time Factors | 1972 |
Probable methylation of nucleic acids of mouse colon by 1,2-dimethylhydrazine in vivo.
Topics: Adenine; Alkylating Agents; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Colon; DNA; Female; Fossil Fuels; Guanine; Hydrazines; Liver; Methylation; Mice; Mice, Inbred Strains; Nucleic Acids; RNA | 1972 |
Guanine-uracil base-pairing.
Topics: Chemical Phenomena; Chemistry; Deoxyuridine; Dimethyl Sulfoxide; Guanine; Guanosine; Magnetic Resonance Spectroscopy; Mathematics; Methylation; Protons; Uracil; Water | 1972 |
Purine N-oxides. 43. 9-Hydroxy-8-methylhypoxanthine, -xanthine, and -guanine.
Topics: Guanine; Hydroxylation; Hypoxanthines; Imidazoles; Methods; Methylation; Purinones; Xanthines | 1972 |
Urinary excretion of methylated purines during the growth of granulation tissue in rat.
Topics: Animals; Cellulose; Chemical Precipitation; Chromatography, Ion Exchange; Chromatography, Paper; Granulation Tissue; Granuloma; Guanine; Liver; Male; Methionine; Methylation; Purines; Rats; RNA; Silver Nitrate; Time Factors; Tritium | 1972 |
Studies on nitrosodimethylamine: preferential methylation of mitochondrial DNA in rats and hamsters.
Topics: Animals; Carbon Isotopes; Carcinogens; Cell Nucleus; Chromatography, Ion Exchange; Cricetinae; DNA; Female; Guanine; Injections, Intraperitoneal; Kidney; Male; Methylation; Mitochondria; Mitochondria, Liver; Nitrosamines; Rats; Rats, Inbred Strains | 1972 |
Interaction between proflavine and chemically methylated deoxyribonucleic acid.
Topics: Acridines; Adenine Nucleotides; Binding Sites; Chemical Phenomena; Chemistry; Circular Dichroism; Cytosine Nucleotides; DNA, Bacterial; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Iodides; Mathematics; Methylation; Micrococcus; Nucleic Acid Denaturation; Polynucleotides; Spectrometry, Fluorescence; Spectrophotometry; Temperature; Vibration; Viscosity | 1972 |
Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine.
Topics: Animals; Carbon Isotopes; Dactinomycin; Ethionine; Guanine; Liver; Liver Neoplasms; Male; Methionine; Methylation; Pyrimidines; Rats; Ribose; RNA, Bacterial; RNA, Transfer | 1972 |
[Nucleosides, V. Synthesis and structure of 8-methyl- and 8-(trifluoromethyl) guanine nucleosides].
Topics: Fluorine; Guanine; Methods; Methylation; Nucleosides; Spectrum Analysis | 1972 |
A study of chemically methylated deoxyribonucleic acid.
Topics: Adenine; Animals; Binding Sites; Cattle; Circular Dichroism; Dialysis; DNA, Bacterial; Filtration; Guanine; Hot Temperature; Luminescent Measurements; Lysine; Methylation; Protein Denaturation; RNA Nucleotidyltransferases; Spermine; Viscosity | 1971 |
Neutral lipids in the study of relationships of members of the family micrococcaceae.
Topics: Acetates; Alkanes; Alkenes; Autoradiography; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Cytosine; DNA, Bacterial; Esters; Fatty Acids; Guanine; Isomerism; Lipids; Methylation; Micrococcus; Sodium; Solvents; Staphylococcus; Transformation, Genetic | 1971 |
Transfer ribonucleic acid methylases during the germination of Neurospora crassa.
Topics: Adenine; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Culture Media; Guanine; Hydrolysis; Methylation; Methyltransferases; Neurospora; Phenols; RNA, Transfer; S-Adenosylmethionine; Spores; Spores, Fungal | 1971 |
Alkylated components in rat liver ribonucleic acid: a possible index of true biological turnover.
Topics: Alkanes; Alkylating Agents; Alkylation; Animals; Guanine; Half-Life; Liver; Methods; Methylation; Orotic Acid; Rats; RNA; RNA, Ribosomal; Sulfonic Acids; Tritium | 1971 |
Purine N-oxides. XXXV. Alkylated guanine 3-oxides and 3-hydroxyxanthines.
Topics: Alkylation; Carcinogens; Cyclic N-Oxides; Guanine; Methylation; Nitrogen Oxides; Oxidation-Reduction; Oxides; Xanthines | 1971 |
Purine N-oxides. XXXVI. The tautomeric structures of the 3-N-oxides of xanthine and guanine.
Topics: Carcinogens; Cyclic N-Oxides; Guanine; Methylation; Nitrogen Oxides; Oxides; Spectrum Analysis; Ultraviolet Rays; Xanthines | 1971 |
[Protonization of purine, adenine, and guanine. NMR spectra and structure of mono, di, and tri cations].
Topics: Adenine; Guanine; Ions; Magnetic Resonance Spectroscopy; Methylation | 1971 |
The stability of rat liver ribonucleic acid in vivo after methylation with methyl methanesulphonate or dimethylnitrosamine.
Topics: Alkanes; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Guanine; Half-Life; Liver; Male; Methylation; Nitrosamines; Orotic Acid; Purines; Rats; RNA; RNA, Ribosomal; RNA, Transfer; Sulfonic Acids; Time Factors; Tritium | 1971 |
Cellular injury and carcinogenesis. The effect of a protein-free high-carbohydrate diet on the metabolism of dimethylnitrosamine in the rat.
Topics: Animals; Dietary Carbohydrates; Dietary Proteins; DNA; Guanine; Kidney; Kidney Neoplasms; Liver; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; RNA; Time Factors | 1971 |
Transfer RNA methylases during sea urchin embryogenesis.
Topics: Acetates; Animals; Carbon Isotopes; Chemical Precipitation; Cytosine Nucleotides; Deoxyribonucleases; Ethanol; Female; Guanine; Hydrolysis; Methionine; Methylation; Methyltransferases; Ovum; Phenols; Potassium; Pronase; RNA, Transfer; S-Adenosylmethionine; Sea Urchins; Time Factors; Tritium; Uracil Nucleotides | 1971 |
Analysis of base composition of RNA and DNA hydrolysates by gas-liquid chromatography.
Topics: Adenine; Animals; Base Sequence; Cattle; Charcoal; Chromatography, Gas; Chromatography, Ion Exchange; Cytosine; DNA; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Ion Exchange Resins; Male; Methods; Methylation; Microchemistry; Purines; Pyrimidines; RNA; Salmonidae; Spermatozoa; Thymine; Thymus Gland; Tissue Extracts; Uracil; Yeasts | 1971 |
Synthesis of 3-methylisoguanine(6-amino-3-methylpurin-2(3H)-one).
Topics: Amines; Cyclization; Deamination; Guanine; Methylation; Purinones; Spectrum Analysis; Stereoisomerism; Ultraviolet Rays | 1971 |
[Reduced toxicity of dimethylnitrosamine in rats and mice after treatment with disulfiram].
Topics: Alkylating Agents; Animals; Carbon Isotopes; Disulfiram; Female; Guanine; Lethal Dose 50; Liver; Methylation; Mice; Nitrosamines; Rats; RNA | 1971 |
In vivo methylation of DNA in human leukocytes.
Topics: Adenine; Cytosine; DNA; Guanine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methylation; Thymine; Tritium | 1971 |
Studies on methylazoxymethanol: methylation of nucleic acids in the fetal rat brain.
Topics: Alkylating Agents; Animals; Blood Chemical Analysis; Brain; Chromatography, Paper; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Nucleic Acids; Placenta; Pregnancy; Proteins; Rats; RNA; Tritium; Urine | 1969 |
Methylation of rat-liver RNA in vivo by methyl methanesulphonate.
Topics: Adenine; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Guanine; Hydrogen-Ion Concentration; Liver; Male; Methylation; Nucleotides; Purinones; Rats; RNA; Solubility; Sulfonic Acids; Time Factors | 1969 |
Methylated bases in DNA of animal origin.
Topics: Animals; Carbon Isotopes; Chick Embryo; Chromatography, Ion Exchange; Chromatography, Paper; Culture Techniques; Cytosine; DNA; DNA, Neoplasm; Guanine; HeLa Cells; Humans; L Cells; Lung; Methionine; Methylation; Peptide Hydrolases; Purinones; Pyrimidinones; Thymine | 1970 |
Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation.
Topics: Acetylcysteine; Animals; Cricetinae; Culture Techniques; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Glutathione; Guanidines; Guanine; L Cells; Methylation; Mice; Nitroso Compounds; Proteins; Salmonidae; Spectrophotometry; Sulfonic Acids; Sulfuric Acids | 1970 |
Estrogen-mediated enhancement of rat liver sRNA methylase activity.
Topics: Adenine; Administration, Oral; Animals; Carbon Isotopes; Castration; Cell Nucleolus; Dactinomycin; Female; Guanine; Hypophysectomy; Injections, Subcutaneous; Liver; Male; Mestranol; Methylation; Nucleosides; Ovary; Pituitary Gland; RNA, Transfer; Sesame Oil; Stimulation, Chemical; Transferases; Uridine | 1970 |
DNA methylation of T-even bacteriophages and of their nonglucosylated mutants: its role in P1-directed restriction.
Topics: Adenine; Chromatography, Paper; Coliphages; DNA, Viral; Filtration; Genetics, Microbial; Guanine; Methylation; Mutation; Spectrophotometry; Transferases; Tritium | 1970 |
[Photochemistry of polynucleotides. IV. Photochemistry of some methylated purinenucleosides].
Topics: Boron Compounds; DNA, Bacterial; Fluorometry; Guanine; Hydrogen-Ion Concentration; Hydrogenation; Methylation; Micrococcus; Nucleic Acid Denaturation; Nucleosides; Optical Rotatory Dispersion; Oxidation-Reduction; Photochemistry; Polynucleotides; Pyrimidines; Radiation Effects; Ultraviolet Rays | 1970 |
Mass spectral analysis of modified ribonucleosides obtained by degradation of 14 alkali-stable dinucleotides isolated from yeast ribonucleic acid.
Topics: Adenine; Base Sequence; Chemical Phenomena; Chemistry; Cytosine; Glycosides; Guanine; Hydrogen-Ion Concentration; Mass Spectrometry; Methods; Methylation; Nucleosides; Pentoses; Polynucleotides; Ribonucleosides; RNA; Spectrum Analysis; Uridine; Yeasts | 1971 |
A simple paper chromatographic method for separation of methylated adenines and cytosine from the major bases found in nucleic acids.
Topics: Adenine; Base Sequence; Carbon Isotopes; Cellulose; Chromatography, Paper; Cytosine; DNA; Guanine; Hydrolysis; Methionine; Methods; Methylation; Nucleic Acids; Nucleotides; Phosphoric Acids; Purines; Pyrimidines; RNA; RNA, Ribosomal; Thymine; Tritium; Uracil | 1971 |
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung; Lung Neoplasms; Lymphoma; Methylation; Mice; Neoplasms, Experimental; Nitroso Compounds; Spleen; Thymus Gland; Thymus Neoplasms; Urea | 1971 |
The reaction of N-methyl-N'-nitro-N-nitrosoguanidine with deoxyribonucleic acid.
Topics: Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; DNA; Guanidines; Guanine; Methylation; Nitroso Compounds | 1968 |
Occurrence of 7-methylguanine in nucleic acids of rat liver.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; DNA; Female; Guanine; Liver; Methionine; Methylation; Microsomes; Rats; RNA; RNA, Transfer; Tritium | 1968 |
Reaction of nitrosoguanidine (N-methyl-N'-nitro-N-nitrosoguanidine) with tobacco mosaic virus and its RNA.
Topics: Adenine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cytosine; Guanidines; Guanine; Methylation; Mutagens; Nitroso Compounds; Phosphorus Isotopes; Purines; Pyrimidines; RNA, Viral; Solutions; Tobacco Mosaic Virus; Uracil | 1968 |
Methylated bases in liver acids from rats treated with dimethylnitrosamine.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Cytosine; DNA; Guanine; Liver; Male; Methylation; Nitrosamines; Rats; RNA | 1968 |
The fate of 7[14C]-methylguanine after administration to the rat.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; DNA; Female; Fetus; Gastric Mucosa; Guanine; Intestine, Large; Intestine, Small; Kidney; Liver; Lung; Methylation; Placenta; Pregnancy; Purines; Rats; RNA | 1968 |
Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate.
Topics: Animals; Carbon Isotopes; Carcinogens; DNA; Guanine; Kidney; Liver; Methylation; Nitrosamines; Nitroso Compounds; Nucleic Acids; Rats; RNA; Sulfates; Sulfonic Acids | 1968 |
Study of the methylation and lack of deamination of deoxyribonucleic acid by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenine; Animals; Animals, Newborn; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteine; DNA; Female; Guanidines; Guanine; Hypoxanthines; Methylation; Nitroso Compounds; Rats; Xanthines | 1969 |
Purine nucleosides. XXIV. A new method for the synthesis of guanine nucleosides. The preparation of 2'-deoxy-alpha and beta-guanosines and the corresponding N2-methyl derivatives.
Topics: Chemical Phenomena; Chemistry; Dactinomycin; DNA; Guanine; Methylation; Nucleosides | 1969 |
Excision of 7-methylguanine from the DNA of Euglena gracilis.
Topics: Alkylating Agents; Animals; Chromatography, Gel; Depression, Chemical; Dextrans; DNA; DNA Replication; Euglena; Guanine; Methylation; Sulfonic Acids | 1969 |
Chemical modification of viral ribonucleic acid. 8. The chemical and biological effects of methylating agents and nitrosoguanidine on tobacco mosaic virus.
Topics: Adenine; Alkylating Agents; Carbon Isotopes; Cytosine; Guanidines; Guanine; Methylation; Mutation; Nitroso Compounds; RNA, Viral; Temperature; Time Factors; Tobacco Mosaic Virus | 1969 |
Methylation in vivo of guanine in the nucleic acids of rat testes by methyl methane sulphonate.
Topics: Animals; Carbon Isotopes; DNA; Fertilization; Guanine; Male; Methylation; Mitosis; Mutation; Nucleic Acids; Rats; RNA; Spermatozoa; Sulfonic Acids; Testis | 1967 |
Analysis of methylated constituents from RNA by thin-layer chromatography.
Topics: Chromatography, Thin Layer; Cytosine Nucleotides; Guanine; Methylation; Nucleotides; Purines; RNA, Transfer; Saccharomyces; Uracil Nucleotides | 1967 |
Theoretical study on the alkylation and protonation of the nucleic acid bases.
Topics: Adenine; Alkylation; Carcinogens; Chemical Phenomena; Chemistry; Cytosine; Guanine; Methylation; Mutagens; Nucleic Acids; Protons; Purines; Pyrimidines; Thermodynamics; Thymine; Uracil | 1984 |
Carcinogen-DNA interaction: differential effects of distamycin-a and spermine on the formation of 7-methylguanine in DNA by N-methyl-N-nitrosourea, methylmethanesulfonate, and dimethylsulfate.
Topics: Animals; Carcinogens; Distamycins; DNA; Drug Interactions; Guanine; Liver; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Pyrroles; Rats; Spermine; Sulfuric Acid Esters | 1980 |
Indirect alkylation of CBA mouse liver DNA and RNA by hydrazine in vivo. A possible mechanism of action as a carcinogen.
Topics: Alkylating Agents; Animals; Carcinogens; DNA; Guanine; Hydrazines; Liver; Male; Methylation; Mice; Mice, Inbred CBA; RNA | 1981 |
In vivo methylation of guanine by the organophosphorus insecticide tetrachlorvinphos.
Topics: Animals; DNA; Guanine; Liver; Male; Methylation; Mice; Propoxur; Proteins; RNA; Tetrachlorvinphos | 1983 |
In vivo replication of carcinogen-modified rat liver DNA: increased susceptibility of O6-methylguanine compared to N-7-methylguanine in replicated DNA to S1-nuclease.
Topics: Animals; Dimethylnitrosamine; DNA Replication; Endonucleases; Guanine; Liver; Male; Methylation; Rats; Single-Strand Specific DNA and RNA Endonucleases; Substrate Specificity | 1980 |
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains.
Topics: Adenoviruses, Human; Cells, Cultured; DNA Repair; Guanine; Humans; Methylation; Methylnitronitrosoguanidine; Neoplasms; Simian virus 40; Sister Chromatid Exchange | 1980 |
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro.
Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine | 1981 |
CG sites and their nucleotide environment in the human gamma-delta-beta-globin gene cluster: distribution, frequency and possible frame for differential methylation.
Topics: Base Sequence; Chromosome Mapping; Cytosine; DNA; DNA Restriction Enzymes; Escherichia coli; Genes; Globins; Guanine; Humans; Methylation | 1983 |
Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference.
Topics: Alkylation; Antigens, Viral, Tumor; Base Sequence; Binding Sites; DNA, Viral; Genes, Viral; Guanine; Methylation; Phosphates; Simian virus 40 | 1984 |
Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.
Topics: Animals; DNA Repair; Escherichia coli; Guanine; Liver; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Poly T; Polydeoxyribonucleotides; Rats; Thymine | 1984 |
Chemical modification of guanine residues of mouse 5 S ribosomal RNA with kethoxal. (Nucleosides and nucleotides 46).
Topics: Aldehydes; Animals; Base Sequence; Butanones; Guanine; Methylation; Mice; Molecular Weight; Nucleic Acid Conformation; Ribonuclease T1; RNA, Ribosomal | 1983 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
Determination of N-7-[2H3]methyl guanine in rat urine by gas chromatography-mass spectrometry following administration of trideuteromethylating agents or precursors.
Topics: Alkylating Agents; Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Guanine; Isotope Labeling; Methylation; Rats | 1984 |
A comparative study of guanine N7-alkylation in mice in vivo by the organophosphorus insecticides trichlorphon, dimethoate, phosmet and bromophos.
Topics: Alkylation; Animals; Biotransformation; Carbon Radioisotopes; Dimethoate; DNA; Guanine; Half-Life; Injections, Intraperitoneal; Insecticides; Kidney; Liver; Male; Methylation; Mice; Organothiophosphates; Organothiophosphorus Compounds; Phosmet; Trichlorfon | 1984 |
Bilirubin incorporation into spiroplasma membranes and methylation of spiroplasmal DNA.
Topics: 5-Methylcytosine; Adenine; Base Composition; Bilirubin; Cell Membrane; Cytosine; DNA, Bacterial; Guanine; Methylation; Spiroplasma | 1984 |
Synthesis and characterization of a set of four dodecadeoxyribonucleoside undecaphosphates containing O6-methylguanine opposite adenine, cytosine, guanine, and thymine.
Topics: Base Composition; Base Sequence; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Circular Dichroism; DNA; Drug Stability; Guanine; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Thermodynamics | 1984 |
Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; DNA; Guanine; Intestine, Large; Methylation; Methylhydrazines; Mice; Precancerous Conditions; Species Specificity; Time Factors | 1983 |
Methylation of liver DNA guanine in hamsters given hydrazine.
Topics: Animals; Cricetinae; DNA; Dose-Response Relationship, Drug; Glutathione; Guanine; Hydrazines; Liver; Male; Mesocricetus; Methylation; Monomethylhydrazine; S-Adenosylmethionine; Time Factors | 1983 |
Evidence for indirect genetic damage as methylation of DNA guanine in response to cytotoxicity.
Topics: Animals; Carcinogens; DNA; Dose-Response Relationship, Drug; Guanine; Guinea Pigs; Hydrazines; Liver; Methylation; Mice; Rats; Rats, Inbred Strains | 1983 |
Methylation of DNA by incubation with methylamine and nitrite.
Topics: Animals; Carbon Radioisotopes; Cattle; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrogen-Ion Concentration; Indicators and Reagents; Methylamines; Methylation; Nitrates; Nitrites; Potassium Compounds; Thymus Gland | 1984 |
Comparison of repair of O6-methylguanine produced by N-methyl-N'-nitro-N-nitrosoguanidine in mouse and human cells.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; DNA Repair; Embryo, Mammalian; Female; Guanine; Humans; Kinetics; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Neoplasms; Neoplasms, Experimental; Species Specificity | 1984 |
Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.
Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Guanine; Humans; Liver; Methylation; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidines; Structure-Activity Relationship | 1984 |
DNA methylation in maternal, fetal and neonatal rat tissues following perinatal administration of procarbazine.
Topics: Animals; Animals, Newborn; Biotransformation; DNA; Female; Fetus; Guanine; Liver; Methylation; Pregnancy; Procarbazine; Rats; Rats, Inbred Strains | 1984 |
Elevated methylation capacity of selected transfer RNA methyltransferases from 9,10-dimethyl-1,2-benzanthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Pregnancy; Rats; Ribonucleosides; RNA, Bacterial; RNA, Transfer; Substrate Specificity; tRNA Methyltransferases | 1980 |
Similar repair of O6-methylguanine in normal and ataxia-telangiectasia fibroblast strains. Deficient repair capacity of lymphoblastoid cell lines does not reflect a genetic polymorphism.
Topics: Ataxia Telangiectasia; Cell Line; Cell Survival; DNA Repair; Guanine; Humans; Kinetics; Lymphocytes; Methylation; Polymorphism, Genetic | 1983 |
Quantitation of O6-methylguanine-DNA methyltransferase in HeLa cells.
Topics: DNA Repair; Guanine; HeLa Cells; Humans; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase | 1983 |
B-Z transition in methylated DNA. A quantum-chemical study.
Topics: Chemical Phenomena; Chemistry; Cytosine; DNA; Guanine; Methylation; Nucleic Acid Conformation; Thermodynamics | 1983 |
Specifically alkylated DNA fragments. Synthesis and physical characterization of d[CGC(O6Me)GCG] and d[CGT(O6Me)GCG].
Topics: Base Sequence; Circular Dichroism; DNA; Guanine; Indicators and Reagents; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Structure-Activity Relationship; Temperature | 1983 |
Modification of DNA repair processes induced by nitrosamines.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Methylation; Rats; Species Specificity | 1983 |
Autoimmune haemolytic disease in mice after exposure to a methylating carcinogen.
Topics: Anemia, Hemolytic, Autoimmune; Animals; DNA; Dose-Response Relationship, Drug; Guanine; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Species Specificity; Spleen; Thymoma; Thymus Neoplasms | 1983 |
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Purines; Rats; Time Factors | 1983 |
Extracts of chronic lymphocytic leukemia lymphocytes have a high level of DNA repair activity fo O6-methylguanine.
Topics: Blood Proteins; Child; DNA Repair; Female; Guanine; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Methylation | 1982 |
Adaptive resynthesis of O6-methylguanine-accepting protein can explain the differences between mammalian cells proficient and deficient in methyl excision repair.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; Female; Guanine; Humans; Kinetics; Methylation; Methylnitronitrosoguanidine; Ovary; Protein Binding | 1982 |
Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.
Topics: Alkylation; Bacterial Proteins; Cysteine; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Methylation; Methyltransferases | 1980 |
Release of 7-methylguanine residues from alkylated DNA by extracts of Micrococcus luteus and Escherichia coli.
Topics: Animals; Cattle; DNA; Escherichia coli; Guanine; Kinetics; Methylation; Micrococcus; Thymus Gland | 1981 |
Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts.
Topics: Adenine; Animals; Cattle; Cricetinae; DNA; DNA Glycosylases; Escherichia coli; Guanine; Kinetics; Liver; Methylation; N-Glycosyl Hydrolases; Rats; Thymus Gland | 1981 |
Mismatch correction at O6-methylguanine residues in E. coli DNA.
Topics: DNA Repair; Escherichia coli; Guanine; Methylation; Methylnitronitrosoguanidine | 1982 |
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.
Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Repair; Guanine; In Vitro Techniques; Methylation; S-Adenosylmethionine; Scintillation Counting; Spectrophotometry, Ultraviolet | 1982 |
The N-terminal arms of lambda repressor wrap around the operator DNA.
Topics: Amino Acid Sequence; Base Sequence; DNA-Binding Proteins; DNA, Bacterial; Guanine; Methylation; Models, Genetic; Operon; Peptide Fragments; Repressor Proteins; Transcription Factors; Trypsin; Viral Proteins; Viral Regulatory and Accessory Proteins | 1982 |
Origin and formation of 1,7-dimethylguanosine in tRNA chemical and enzymatic methylation.
Topics: Animals; Dimethylnitrosamine; Guanine; Guanosine; Kidney; Liver; Male; Methylation; Rats; RNA, Transfer | 1982 |
Reactivity of methylazoxymethanol and its metabolites with nucleophilic centers of DNA bases: a semi-empirical NDDO molecular orbital study.
Topics: Azo Compounds; Cytosine; DNA; Guanine; Hydrogen Bonding; Methylation; Methylazoxymethanol Acetate; Molecular Conformation; Thermodynamics | 1982 |
N-Sulfomethylation of guanine, adenine and cytosine with formaldehyde-bisulfite. A selective modification of guanine in DNA.
Topics: Adenine; Cytosine; DNA; Formaldehyde; Guanine; Methylation; Molecular Conformation; Nucleosides; Nucleotides; Structure-Activity Relationship; Sulfites | 1982 |
Repair of O6-methyl-guanine residues in DNA takes place by a similar mechanism in extracts from HeLa cells, human liver, and rat liver.
Topics: Animals; DNA; DNA Glycosylases; DNA Repair; Guanine; HeLa Cells; Humans; Liver; Methylation; Methylnitronitrosoguanidine; Methyltransferases; Molecular Weight; N-Glycosyl Hydrolases; O(6)-Methylguanine-DNA Methyltransferase; Proteins; Rats | 1982 |
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.
Topics: Chromatography, High Pressure Liquid; DNA Glycosylases; DNA, Bacterial; Guanine; Methylation; Micrococcus; N-Glycosyl Hydrolases; S-Adenosylmethionine | 1982 |
Susceptibility of dimethylnitrosamine induced O6-methylguanine containing regions in in vivo replicated, hybrid rat liver DNA towards S1 nuclease.
Topics: Animals; Bromodeoxyuridine; Deoxyribonucleases; Dimethylnitrosamine; DNA; DNA Replication; Guanine; Liver; Male; Methylation; Nucleic Acid Hybridization; Rats | 1980 |
Methylation of CpG sequences in eukaryotic DNA.
Topics: Animals; Base Sequence; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Guanine; Kinetics; Methylation; Methyltransferases; Mice; Species Specificity; Substrate Specificity | 1981 |
Effect of methionine sulfoximine on methylation of guanine residues in astroglial transfer ribonucleic acids.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Guanine; Guanosine; Kinetics; Methionine Sulfoximine; Methylation; Neuroglia; Rats; RNA, Transfer | 1981 |
Alkylation of nucleic acids and metabolism of small doses of dimethylnitrosamine in the rat.
Topics: Alkylating Agents; Animals; Dimethylnitrosamine; DNA; Female; Gastric Mucosa; Guanine; Intestine, Small; Liver; Methylation; Rats | 1981 |
[DNA methylation characteristics of different fetal and maternal body tissues in rats administered 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenine; Animals; Dimethylhydrazines; DNA; Female; Fetus; Guanine; Methylation; Methylhydrazines; Pregnancy; Rats; Tissue Distribution | 1981 |
Mode of action of methylating carcinogens: comparative studies of murine and human cells.
Topics: Animals; Carcinogens; Cells, Cultured; DNA; Guanine; Humans; Lymphocytes; Methylation; Methylnitrosourea; Mice; Mice, Inbred Strains; Species Specificity | 1981 |
Effect of pretreatment of rats with N-methyl-N-nitrosourea on the repair of O(6)-methylguanine in liver DNA.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; DNA Repair; Guanine; Male; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats | 1981 |
A system in mouse liver for the repair of O6-methylguanine lesions in methylated DNA.
Topics: Amino Acids; Animals; DNA; DNA Repair; Guanine; Kinetics; Liver; Male; Methylation; Methylnitrosourea; Mice; Mice, Inbred C57BL; Proteins | 1981 |
In vivo kinetics of O6-methylguanine and 7-methylguanine formation and persistence in DNA of rats treated with symmetrical dimethylhydrazine.
Topics: Animals; Brain; Colon; Dimethylhydrazines; DNA; Guanine; Half-Life; Kidney; Kinetics; Liver; Lung; Male; Methylation; Methylhydrazines; Pancreas; Rats; Rats, Inbred Strains | 1981 |
Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.
Topics: Adolescent; Adult; Alkylating Agents; Ataxia Telangiectasia; Cell Division; Cells, Cultured; Child; DNA; DNA Repair; Female; Guanine; Humans; Infant, Newborn; Kinetics; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea | 1981 |
Methylation of liver DNA guanine in hydrazine hepatotoxicity: dose-response and kinetic characteristics of 7-methylguanine and O6-methylguanine formation and persistence in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; DNA; Dose-Response Relationship, Drug; Guanine; Hydrazines; Kinetics; Liver; Male; Methylation; Rats | 1981 |
Stimulation of transfer of methyl groups from O6-methylguanine in DNA to protein by rat liver extracts in response to hepatotoxins.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Guanine; Liver Extracts; Male; Methylation; Proteins; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors | 1981 |
Alkylation of DNA by organophosphorus pesticides.
Topics: Alkylating Agents; Animals; Dichlorvos; DNA; Guanine; Insecticides; Methylation; Rats | 1981 |
Cerebellar tRNA methyltransferases: a developmental study.
Topics: Aging; Animals; Cerebellum; Cytosine; Guanine; Kinetics; Male; Methylation; Purkinje Cells; Rats; tRNA Methyltransferases | 1980 |
Distribution and repair of O6-methylguanine in different fractions of rat liver DNA after dimethylnitrosamine administration.
Topics: Animals; Chromatin; Dimethylnitrosamine; DNA Repair; DNA, Single-Stranded; Guanine; Liver; Male; Methylation; Nucleic Acid Denaturation; Rats | 1980 |
Methylation of DNA by N-nitroso-2-oxopropylpropylamine: formation of O6- and 7-methylguanine and studies on the methylation mechanism.
Topics: Animals; Carcinogens; DNA; Guanine; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Liver; Male; Methylation; Microsomes, Liver; Nitrosamines; Oxidation-Reduction; Rats | 1980 |
Increased concentration of 7-methylguanine and 1-methylhypoxanthine in urine of rats bearing Yoshida tumour.
Topics: Animals; Chromatography, Liquid; Guanine; Hypoxanthines; Methylation; Rats; RNA, Transfer; Sarcoma, Yoshida | 1980 |
Methylated purines in human liver DNA after probable dimethylnitrosamine poisoning.
Topics: Adult; Chromatography, Liquid; Dimethylnitrosamine; DNA; Guanine; Humans; Liver; Male; Methylation; Purines | 1980 |
[Accumulation of methylated purines in the liver and large intestine DNA of rats following repeated administrations of 1,2-dimethylhydrazine].
Topics: Adenine; Animals; Dimethylhydrazines; DNA; Guanine; Intestine, Large; Liver; Male; Methylation; Methylhydrazines; Rats | 1980 |
Formation of a parallel-stranded DNA homoduplex by d(GGA) repeat oligonucleotides.
Topics: Base Composition; Base Sequence; DNA; Guanine; Hydrogen Bonding; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Hybridization; Polydeoxyribonucleotides; Trinucleotide Repeats | 1995 |
The fragile X syndrome single strand d(CGG)n nucleotide repeats readily fold back to form unimolecular hairpin structures.
Topics: Base Sequence; Cysteine; Diethyl Pyrocarbonate; DNA Replication; Fragile X Mental Retardation Protein; Fragile X Syndrome; Guanine; Humans; Methylation; Molecular Probes; Molecular Sequence Data; Nerve Tissue Proteins; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Repetitive Sequences, Nucleic Acid; RNA-Binding Proteins; Transcription, Genetic | 1995 |
Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Biotransformation; Carcinogens; Cell Nucleus; Cricetinae; DNA; DNA Adducts; DNA Damage; Guanine; Immunohistochemistry; Liver; Lung; Male; Mesocricetus; Methylation; Mice; Nasal Cavity; Nitrosamines; Rats; Rats, Sprague-Dawley; Respiratory System; Staining and Labeling; Trachea | 1994 |
Single strand targeted triplex-formation. Destabilization of guanine quadruplex structures by foldback triplex-forming oligonucleotides.
Topics: Base Sequence; DNA; DNA, Antisense; G-Quadruplexes; Genes, gag; Guanine; HIV-1; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Potassium; RNA; RNA, Antisense; Sodium | 1995 |
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Zinc(II) ions selectively interact with DNA sequences present at the TFIIIA binding site of the Xenopus 5S-RNA gene.
Topics: Animals; Base Sequence; Binding Sites; DNA; DNA-Binding Proteins; Electrochemistry; Guanine; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid; RNA, Ribosomal, 5S; Sulfuric Acid Esters; Transcription Factor TFIIIA; Transcription Factors; Xenopus; Zinc | 1995 |
Effects of dietary restriction and fasting on selected rat liver enzymes of xenobiotic metabolism and on AOM-induced DNA guanine methylation in rat liver and colon.
Topics: Aniline Hydroxylase; Animals; Azo Compounds; Benzopyrene Hydroxylase; Colon; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; DNA; Fasting; Food Deprivation; Glutathione Transferase; Guanine; Liver; Male; Methylation; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred F344; Xenobiotics | 1995 |
A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells.
Topics: Alkylating Agents; B-Lymphocytes; Cell Line; Chromosome Aberrations; Dimethylnitrosamine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Erythroid Precursor Cells; Guanine; Humans; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea | 1995 |
Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine.
Topics: Alanine; Animals; Arginine; Base Sequence; Cattle; DNA; DNA Repair; DNA-Binding Proteins; Guanine; Humans; Methylation; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase | 1995 |
DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase.
Topics: Base Sequence; Binding Sites; DNA Adducts; DNA Modification Methylases; DNA-Cytosine Methylases; Female; Guanine; Humans; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; Placenta; Pregnancy; Reactive Oxygen Species | 1995 |
A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage.
Topics: Cell Survival; DNA Damage; DNA Repair; DNA, Neoplasm; DNA, Satellite; Dose-Response Relationship, Drug; Drug Resistance; Genetic Complementation Test; Guanine; HeLa Cells; Humans; Methylation; Methylnitrosourea; Methyltransferases; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Thioguanine | 1995 |
Retinoid X receptor alpha binds with the highest affinity to an imperfect direct repeat response element.
Topics: Animals; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; DNA; Escherichia coli; Gene Expression; Guanine; Macromolecular Substances; Methylation; Mice; Molecular Sequence Data; Mutagenesis; Receptors, Retinoic Acid; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Retinoid X Receptors; Transcription Factors; Transfection | 1995 |
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; DNA, Neoplasm; Female; Genes, ras; Guanine; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Point Mutation; Polymorphism, Restriction Fragment Length; Pyridines; Thymine | 1993 |
O6-methylguanine-DNA adducts in rat lymphocytes after in vivo exposure to N-nitrosodimethylamine (NDMA).
Topics: Animals; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Guanine; Immunoenzyme Techniques; Liver; Lymphocytes; Male; Methylation; Nitroso Compounds; Rats; Rats, Sprague-Dawley | 1994 |
New restriction endonuclease CviRI cleaves DNA at TG/CA sequences.
Topics: Animals; Base Sequence; Binding Sites; Chlorella; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; Guanine; Humans; Methylation; Substrate Specificity | 1994 |
Purification and biochemical characterization of recombinant N-methylpurine-DNA glycosylase of the mouse.
Topics: Adenine; Amino Acid Sequence; Animals; DNA; DNA Glycosylases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Magnesium Chloride; Methylation; Mice; Molecular Sequence Data; N-Glycosyl Hydrolases; Recombinant Proteins; Sodium Chloride; Spermine; Substrate Specificity | 1994 |
Demethylation of O6-methylguanine in DNA by O6-methylguanine-DNA methyltransferase: synthesis and characterization of O6,9-dimethylguanine coordinated with cis-platin at the N7-position.
Topics: Animals; Cisplatin; DNA; DNA Damage; Guanine; Kinetics; Leukemia L1210; Methylation; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds | 1994 |
Comparison of 7-medG formation in white blood cells, liver and target organs in rats treated with methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; DNA; Guanine; Leukocytes; Liver; Male; Methylation; Nitrosamines; Rats | 1994 |
Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides.
Topics: Acridines; Base Sequence; Deoxyribonuclease I; DNA; Guanine; Hydrogen-Ion Concentration; Magnesium; Manganese; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides | 1994 |
Hydralazine and other hydrazine derivatives and the formation of DNA adducts.
Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; DNA; Dose-Response Relationship, Drug; Formaldehyde; Guanine; Hydralazine; Hydrazines; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley | 1994 |
Dimethylsulfate methylation of guanine residues in mammalian DNA: inverse correlation between methylation susceptibility and mutagenesis by bromodeoxyuridine and thymidine.
Topics: Animals; Bromodeoxyuridine; Dinucleoside Phosphates; DNA Modification Methylases; DNA Mutational Analysis; Genetic Vectors; Guanine; Hypoxanthine Phosphoribosyltransferase; Methylation; Mice; Mutagenesis; Mutagens; Point Mutation; Stereoisomerism; Sulfuric Acid Esters; Thymidine | 1993 |
Interaction of the NH2- and COOH-terminal domains of the FLP recombinase with the FLP recognition target sequence.
Topics: Adenine; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyribonuclease I; DNA Nucleotidyltransferases; DNA, Fungal; Fungal Proteins; Guanine; Methylation; Molecular Sequence Data; Peptides; Saccharomyces cerevisiae; Substrate Specificity; Ultraviolet Rays | 1994 |
DNA mismatch binding and incision at modified guanine bases by extracts of mammalian cells: implications for tolerance to DNA methylation damage.
Topics: Base Sequence; Dealkylation; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Methylation; Molecular Sequence Data; Protein Binding; Thioguanine; Tumor Cells, Cultured | 1994 |
An element of the elastase I enhancer is an overlapping bipartite binding site activated by a heteromeric factor.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythroid-Specific DNA-Binding Factors; Guanine; Islets of Langerhans; Methylation; Mice; Molecular Sequence Data; Pancreas; Pancreatic Elastase; Transcription Factors | 1994 |
DNA methylation by N-methyl-N-nitrosourea: methylation pattern changes in single- and double-stranded DNA, and in DNA with mismatched or bulged guanines.
Topics: Autoradiography; Base Sequence; Circular Dichroism; DNA; DNA, Single-Stranded; Guanine; Hot Temperature; Methylation; Methylnitrosourea; Molecular Sequence Data; Nucleic Acid Heteroduplexes | 1993 |
Retention and 5' cap trimethylation of U3 snRNA in the nucleus.
Topics: Animals; Cell Nucleolus; Cell Nucleus; Cytoplasm; Guanine; Methylation; Oocytes; RNA Caps; RNA, Small Nuclear; Xenopus laevis | 1994 |
The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.
Topics: Base Sequence; DNA, Fungal; Fungal Proteins; GTP-Binding Proteins; Guanine; Methylation; Models, Genetic; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Protein Binding; rap GTP-Binding Proteins; Saccharomyces cerevisiae; Telomere | 1994 |
Effect of alkyl sulfides on diazomethane-induced methylation of DNA in vitro.
Topics: Allyl Compounds; Animals; Cattle; Diazomethane; DNA; DNA Damage; Evaluation Studies as Topic; Guanine; Methylation; Sulfides | 1993 |
Genetic consequences of tolerance to methylation DNA damage in mammalian cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Aza Compounds; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; Mutation; Ouabain; Thioguanine | 1993 |
Methylation interference experiments identify bases that are essential for distinct catalytic functions of a group I ribozyme.
Topics: Bacteriophage T4; Base Sequence; Binding Sites; Catalysis; Guanine; Introns; Magnesium; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; RNA Splicing; RNA, Catalytic; RNA, Viral | 1993 |
[DNA methylation of monohalogenated methanes of F344 rats].
Topics: Animals; Chromatography, High Pressure Liquid; DNA; Guanine; Hydrocarbons, Brominated; Hydrocarbons, Iodinated; Male; Methyl Chloride; Methylation; Rats; Rats, Inbred F344 | 1993 |
Quantitation of genomic methylation using ligation-mediated PCR.
Topics: Animals; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; Enhancer Elements, Genetic; Guanine; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 1993 |
O6-methylguanine in DNA inhibits replication in vitro by human cell extracts.
Topics: Antigens, Polyomavirus Transforming; Deoxyribonucleases, Type II Site-Specific; DNA Repair; DNA Replication; DNA, Viral; Guanine; HeLa Cells; Humans; Kinetics; Methylation; Methylnitrosourea; Plasmids; Simian virus 40 | 1993 |
Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Repair; Genes, p53; Guanine; Humans; Methylation; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase | 1994 |
Probing CpG methylation at CACGTG with BbrPI restriction enzyme.
Topics: Base Sequence; Binding Sites; Cytosine; Deoxyribonucleases, Type II Site-Specific; Dinucleoside Phosphates; Guanine; Methylation; Oligonucleotides | 1993 |
Homologous recognition and triplex formation promoted by RecA protein between duplex oligonucleotides and single-stranded DNA.
Topics: Adenine; Base Sequence; Cytosine; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Exonucleases; Guanine; Hydrogen Bonding; Kinetics; Methylation; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrolines; Rec A Recombinases; Substrate Specificity; Temperature | 1993 |
Molecular organization and chromosomal location of human GC-rich heterochromatic blocks.
Topics: Base Sequence; Chromosome Mapping; Cytidine; Deoxyribonucleases, Type II Site-Specific; Guanine; Heterochromatin; Humans; Methylation; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid | 1993 |
Mass spectrometric investigation of the presence of 7-methyl ring-opened guanine derivatives in urine.
Topics: Alkylation; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Mass Spectrometry; Methylation | 1993 |
Location of close contacts between Escherichia coli RNA polymerase and guanine residues at promoters either with or without consensus -35 region sequences.
Topics: Base Composition; Base Sequence; Consensus Sequence; DNA Mutational Analysis; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Galactose; Guanine; Lac Operon; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Structure-Activity Relationship; Transcription, Genetic | 1993 |
Effect of 5-methylcytosine as a neighboring base on methylation of DNA guanine by N-methyl-N-nitrosourea.
Topics: 5-Methylcytosine; Autoradiography; Base Sequence; Cytosine; DNA; DNA Damage; Guanine; Humans; Methylation; Methylnitrosourea; Molecular Sequence Data | 1993 |
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
Topics: Base Sequence; Bronchi; Calcitonin; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 3; Cytosine; DNA; Epithelium; Guanine; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Tumor Cells, Cultured | 1993 |
Identification of CpG island at the 5' end of murine leukemia inhibitory factor gene.
Topics: Animals; Base Composition; Base Sequence; Blotting, Southern; Conserved Sequence; Cytosine; Exons; Growth Inhibitors; Guanine; Humans; Interleukin-6; Introns; Leukemia Inhibitory Factor; Lymphokines; Methylation; Mice; Sheep | 1993 |
Inhibition by phenylethyl and phenylhexyl isothiocyanate of metabolism of and DNA methylation by N-nitrosomethylamylamine in rats.
Topics: Animals; Carcinogens; DNA; Esophagus; Guanine; Isothiocyanates; Liver; Methylation; Microsomes; Microsomes, Liver; Nitrosamines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thiocyanates | 1993 |
Transcription of the HIV-1 LTR is regulated by the density of DNA CpG methylation.
Topics: Cell Line; Cytosine; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Viral; Gene Products, tat; Guanine; HeLa Cells; HIV Long Terminal Repeat; HIV-1; Humans; Methylation; Nucleotides; Plasmids; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transcriptional Activation | 1993 |
Pyridyloxobutyl DNA adducts inhibit the repair of O6-methylguanine.
Topics: Alkylation; Animals; Cattle; DNA; DNA Repair; Guanine; Liver; Methylation; Methyltransferases; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Pyridines; Rats | 1993 |
Repair of N-methylpurines in the mitochondrial DNA of xeroderma pigmentosum complementation group D cells.
Topics: Blotting, Southern; Cell Line; DNA Damage; DNA Repair; DNA, Mitochondrial; Genetic Complementation Test; Guanine; Humans; Methylation; Methylnitrosourea; Xeroderma Pigmentosum | 1993 |
Frequency of Ki-ras mutations and DNA alkylation in colorectal tissue from individuals living in Manchester.
Topics: Base Sequence; Colon; Colorectal Neoplasms; DNA Damage; DNA Primers; England; Genes, ras; Guanine; Humans; Methylation; Molecular Sequence Data; Point Mutation; Proto-Oncogene Proteins p21(ras) | 1996 |
In vivo footprinting of the mouse inducible nitric oxide synthase gene: inducible protein occupation of numerous sites including Oct and NF-IL6.
Topics: Animals; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Cytokines; DNA; DNA Footprinting; DNA-Binding Proteins; Enhancer Elements, Genetic; Enzyme Induction; Guanine; Interferon Regulatory Factor-1; Lipopolysaccharides; Macrophages; Methylation; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide Synthase; Nuclear Proteins; Phosphoproteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Transcription Factors; Transcription, Genetic | 1996 |
Measurement of oxidized and methylated DNA bases by HPLC with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; DNA; DNA Damage; Electrochemistry; Guanine; Methylation; Oxidation-Reduction; Purines; Pyrimidines; Uracil | 1996 |
Dimethyl sulfate uptake and methylation of DNA in rat respiratory tissues following acute inhalation.
Topics: Administration, Inhalation; Animals; Atmosphere Exposure Chambers; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Guanine; Lung; Male; Methylation; Mucociliary Clearance; Mucous Membrane; Rats; Respiration; Respiratory System; Sulfuric Acid Esters; Time Factors | 1995 |
Induction of hprt gene mutations in splenic T-lymphocytes from the rat exposed in vivo to DNA methylating agents is correlated with formation of O6-methylguanine in bone marrow and not in the spleen.
Topics: Alkylating Agents; Animals; Bone Marrow; Guanine; Hypoxanthine Phosphoribosyltransferase; Lung; Male; Methylation; Mutagenicity Tests; Mutagens; Point Mutation; Rats; Rats, Inbred Lew; Spleen; T-Lymphocytes | 1996 |
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Topics: Antineoplastic Agents, Alkylating; Carmustine; Colonic Neoplasms; Dacarbazine; DNA Adducts; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Solution structure of RNA duplexes containing alternating CG base pairs: NMR study of r(CGCGCG)2 and 2'-O-Me(CGCGCG)2 under low salt conditions.
Topics: Base Composition; Cytosine; Guanine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligoribonucleotides; Phosphorus Radioisotopes; Protons; Ribose; RNA; Sodium Chloride; Solutions; Temperature | 1997 |
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells.
Topics: Animals; Antineoplastic Agents; CHO Cells; Cricetinae; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylation; O(6)-Methylguanine-DNA Methyltransferase | 1998 |
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine; Humans; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Temozolomide; Tumor Cells, Cultured | 1996 |
O6-Alkylguanine-DNA alkyltransferase: influence on susceptibility to the genetic effects of alkylating agents.
Topics: Alkylating Agents; DNA; DNA Repair; Guanine; Humans; Methylation; O(6)-Methylguanine-DNA Methyltransferase | 1998 |
Oligonucleotide sequencing using guanine-specific methylation and electrospray ionization ion trap mass spectrometry.
Topics: Guanine; Mass Spectrometry; Methylation; Oligonucleotides | 1999 |
The cytotoxicity of DNA carboxymethylation and methylation by the model carboxymethylating agent azaserine in human cells.
Topics: Adenine; Alkylating Agents; Azaserine; Azo Compounds; Burkitt Lymphoma; Carcinogens; DNA Adducts; DNA Damage; DNA Methylation; Drug Resistance; Enzyme Induction; Genetic Complementation Test; Glycine; Guanine; Humans; Lymphocytes; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured; Xeroderma Pigmentosum | 1999 |
Putative RNA capping activities encoded by brome mosaic virus: methylation and covalent binding of guanylate by replicase protein 1a.
Topics: Amino Acid Sequence; Bromovirus; Cell Membrane; Guanine; Guanosine Triphosphate; Methylation; Molecular Sequence Data; Point Mutation; Protein Binding; RNA Caps; RNA Processing, Post-Transcriptional; RNA-Dependent RNA Polymerase; RNA, Viral; Sequence Homology, Amino Acid; Substrate Specificity; tRNA Methyltransferases | 1999 |
A 66-base-pair enhancer module activates the expression of a distinct isoform of UDP-glucuronosyltransferase family 1 (UGT1A2) in primary hepatocytes.
Topics: Animals; Base Sequence; Binding Sites; Cells, Cultured; Deoxyribonuclease I; Enhancer Elements, Genetic; Enzyme Activation; Genes, Reporter; Glucuronosyltransferase; Guanine; Immunoblotting; Liver; Male; Methylation; Models, Genetic; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Isoforms; Rats; Rats, Gunn; Rats, Wistar; RNA, Messenger; Transcription, Genetic | 2000 |
Method for the synthesis of uric acid derivatives.
Topics: 1-Propanol; Adenine; Alkylation; Ammonia; Guanine; Hydrocarbons, Iodinated; Mass Spectrometry; Methylation; Purines; Uric Acid | 2000 |
N-nitrosodimethylamine-mediated formation of oxidized and methylated dna bases in a cytochrome P450 2E1 expressing cell line.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Ascorbic Acid; Cell Death; Cell Line; Cytochrome P-450 CYP2E1; Deoxyguanosine; Dimethylnitrosamine; DNA; DNA Adducts; DNA Methylation; Guanine; Methylation; Oxidation-Reduction; Rats | 2001 |
The in vivo levels of DNA alkylation products in human lymphocytes are not age dependent: an assay of 7-methyl- and 7-(2-hydroxyethyl)-guanine DNA adducts.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; DNA Repair; Guanine; Humans; Lipid Peroxidation; Lymphocytes; Methylation; Middle Aged; Time Factors | 2002 |
Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy.
Topics: Adenine; Binding Sites; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Guanine; Methylation; RNA, Ribosomal, 23S; Streptomyces; Tylosin | 2002 |
Charge distribution in 7-methylguanine regarding cation-pi interaction with protein factor eIF4E.
Topics: Biophysical Phenomena; Biophysics; Carbon; Cations; Electrons; Eukaryotic Initiation Factor-4E; Guanine; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methylation; Models, Chemical; RNA Cap Analogs; RNA Caps; RNA, Messenger; Temperature | 2003 |
METHYLATION OF RIBONUCLEIC ACIDS OF LIVER AND OTHER ORGANS IN DIFFERENT SPECIES TREATED WITH C14- AND H3-DIMETHYLNITROSAMINES IN VIVO.
Topics: Animals; Carbon Isotopes; Carcinogens; Chemical and Drug Induced Liver Injury; Chromatography; Cricetinae; Dimethylnitrosamine; Guanine; Guinea Pigs; Hepatitis; Kidney; Liver; Methylation; Mice; Neoplasms; Nitrosamines; Nucleotides; Proteins; Pyrimidines; Rats; Research; RNA; Spleen; Toxicology; Tritium | 1964 |
METHYLATION OF DEOXYRIBONUCLEIC ACID BY DIAZOMETHANE.
Topics: Adenine; Animals; Azo Compounds; Diazomethane; DNA; Fishes; Guanine; Male; Methylation; Phosphates; Research; RNA; Spectrophotometry; Spermatozoa | 1964 |
METHYLATED PURINES AND PYRIMIDINES. I. SYNTHESES OF 8-HYDROXY-7-METHYLGUANINE AND METHYLATION OF A 5-(BENZYLIDENEAMINO) PYRIMIDINE.
Topics: Acetates; Alkylation; Chemical Phenomena; Chemistry; Guanine; Malonates; Methylation; Purines; Pyrimidines; Research | 1965 |
O6-alkylguanine-DNA alkyltransferases repair O6-methylguanine in DNA with Michaelis-Menten-like kinetics.
Topics: Chromatography, High Pressure Liquid; DNA Damage; DNA Repair; DNA Repair Enzymes; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanine; Kinetics; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phosphorus Radioisotopes; Substrate Specificity; Temperature; Time Factors | 2003 |
Prereplicative purine methylation and postreplicative demethylation in each DNA duplication of the Escherichia coli replication cycle.
Topics: Animals; DNA; DNA Methylation; DNA Modification Methylases; DNA Restriction Enzymes; Escherichia coli; Exodeoxyribonucleases; Guanine; Magnesium; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Phenotype; Plasmids; Protein Conformation; Purines | 2004 |
Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).
Topics: Chromatography, Thin Layer; Dithiothreitol; DNA Methylation; DNA, Complementary; Dose-Response Relationship, Drug; Guanine; Guanosine; Guanosine Diphosphate; Methylation; Methyltransferases; Protein Binding; Recombinant Proteins; RNA; RNA, Small Nucleolar; S-Adenosylmethionine; Schizosaccharomyces; Time Factors | 2005 |
DNA methylation, cell proliferation, and histopathology in rats following repeated inhalation exposure to dimethyl sulfate.
Topics: Adenine; Administration, Inhalation; Alkylating Agents; Animals; Body Weight; Cell Proliferation; DNA; DNA Adducts; DNA Methylation; Guanine; Male; Methylation; Models, Biological; Mutagens; Olfactory Mucosa; Purines; Rats; Risk; Sulfuric Acid Esters | 2004 |
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Giardia lamblia; Glutamic Acid; Glycerol; Green Fluorescent Proteins; Guanine; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methylation; Methyltransferases; Molecular Sequence Data; Recombinant Proteins; RNA; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Transfection; tRNA Methyltransferases; Tryptophan | 2005 |
Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C.
Topics: 5-Methylcytosine; Acetylation; Base Sequence; Cell Nucleus; Cytoplasm; DNA-Binding Proteins; Guanine; Methylation; Molecular Sequence Data; Protein Kinases; Protein Serine-Threonine Kinases; Ribonucleoproteins; RNA, Fungal; RNA, Transfer, His; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; tRNA Methyltransferases | 2005 |
Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors.
Topics: Clodronic Acid; Cyclopropanes; Drug Design; Enzyme Inhibitors; Fluorides; Guanine; Hypoxanthines; Kinetics; Methylation; Phosphoric Acids; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Substrate Specificity | 2006 |
Potential energy surfaces of the microhydrated guanine...cytosine base pair and its methylated analogue.
Topics: Base Pairing; Computer Simulation; Cytosine; Guanine; Hydrogen Bonding; Methylation; Models, Molecular; Molecular Structure; Water | 2006 |
A unique strategy for mRNA cap methylation used by vesicular stomatitis virus.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cricetinae; Gene Expression Regulation, Viral; Guanine; Methylation; Molecular Sequence Data; Mutation; Phenotype; Recombinant Proteins; RNA Caps; Sequence Alignment; tRNA Methyltransferases; Vesicular stomatitis Indiana virus; Viral Proteins | 2006 |
Carbocations from oxidized metabolites of benzo[a]anthracene: a computational study of their methylated and fluorinated derivatives and guanine adducts.
Topics: Benz(a)Anthracenes; Biotransformation; Cations; Computer Simulation; DNA Adducts; Fluorine; Guanine; Methylation; Models, Biological; Molecular Structure; Oxidation-Reduction; Signal Transduction | 2006 |
Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
Topics: Animals; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models, Animal; DNA Damage; Glioblastoma; Guanine; Humans; Methylation; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Mutational analysis of Encephalitozoon cuniculi mRNA cap (guanine-N7) methyltransferase, structure of the enzyme bound to sinefungin, and evidence that cap methyltransferase is the target of sinefungin's antifungal activity.
Topics: Adenosine; Antifungal Agents; Binding Sites; Crystallography, X-Ray; DNA Mutational Analysis; Encephalitozoon cuniculi; Guanine; Kinetics; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Saccharomyces cerevisiae | 2006 |
Synthesis and hybridization properties of 2'-O-methyl-RNA incorporating 3-deazaguanine derivatives.
Topics: Base Pair Mismatch; Base Pairing; Guanine; Methylation; Nucleic Acid Hybridization; RNA; Temperature | 2005 |
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
Topics: Escherichia coli; Escherichia coli Proteins; Guanine; Methylation; Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 16S | 2007 |
Highly selective recognition of cytosine over uracil and adenine by a guanine analogue, 2-N-acetyl-3-deazaguanine, in 2'-O-methyl-RNA/RNA and DNA duplexes.
Topics: Adenine; Base Pairing; Base Sequence; Cytosine; DNA; Guanine; Methylation; Models, Chemical; RNA, Double-Stranded; Uracil | 2007 |
Model transition states for methane diazonium ion methylation of guanine runs in oligomeric DNA.
Topics: Diazonium Compounds; DNA; Guanine; Methane; Methylation; Models, Molecular; Mutation; Quantum Theory; Thermodynamics | 2007 |
A 2'-methyl or 2'-methylene group at G+1 in precursor tRNA interferes with Mg2+ binding at the enzyme-substrate interface in E-S complexes of E. coli RNase P.
Topics: Adenine; Base Sequence; Cations, Divalent; Escherichia coli; Guanine; Magnesium; Methane; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; Ribonuclease P; RNA Interference; RNA Precursors; RNA, Transfer; Substrate Specificity | 2007 |
A deoxyribozyme with a novel guanine quartet-helix pseudoknot structure.
Topics: Base Sequence; Binding Sites; Buffers; Catalysis; Circular Dichroism; DNA, Catalytic; G-Quadruplexes; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Molecular Structure; Mutation; Nucleic Acid Conformation; Oligonucleotides; Phosphorylation; Repetitive Sequences, Nucleic Acid; Selection, Genetic; Substrate Specificity | 2008 |
Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine.
Topics: Adenine; Antiviral Agents; Cell Line; Cyclopropanes; Fluorine Compounds; Guanine; Hepacivirus; Hydroxylation; Isomerism; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Nucleosides | 2008 |
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression.
Topics: Cell Line, Tumor; Cells, Cultured; Chromatin; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enhancer Elements, Genetic; Estradiol; Estrogen Receptor alpha; Gene Expression Regulation; Genes, bcl-2; Guanine; Histone Demethylases; Histones; Humans; Hydrogen Peroxide; Lysine; Methylation; Nucleic Acid Conformation; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; RNA Polymerase II; Transcription, Genetic | 2008 |
Variations in arsenic methylation capacity and oxidative DNA lesions over a 2-year period in a high arsenic-exposed population.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Arsenic Poisoning; Arsenicals; Child; DNA; DNA Damage; Environmental Exposure; Environmental Pollutants; Female; Guanine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; Sweden; Young Adult | 2009 |
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA.
Topics: Amino Acid Sequence; Bacteria; Bacterial Proteins; Base Sequence; Biocatalysis; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guanine; Kinetics; Mass Spectrometry; Methylation; Microbial Viability; Models, Biological; Molecular Sequence Data; Mutant Proteins; Nucleic Acid Conformation; Recombinant Proteins; RNA, Messenger; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases | 2009 |
Ribose 2'-O methylation of the vesicular stomatitis virus mRNA cap precedes and facilitates subsequent guanine-N-7 methylation by the large polymerase protein.
Topics: Amino Acid Substitution; Base Sequence; Binding Sites; DNA-Directed RNA Polymerases; Guanine; Methylation; Methyltransferases; Ribose; RNA Caps; RNA, Messenger; Vesiculovirus; Viral Proteins | 2009 |
Methylation at 5HTT mediates the impact of child sex abuse on women's antisocial behavior: an examination of the Iowa adoptee sample.
Topics: Adoption; Adult; Adult Survivors of Child Abuse; Antisocial Personality Disorder; Base Sequence; Child; Child Abuse, Sexual; Cytosine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Guanine; Humans; Methylation; Promoter Regions, Genetic; Serotonin Plasma Membrane Transport Proteins | 2011 |
Control of self-assembled 2D nanostructures by methylation of guanine.
Topics: DNA; Graphite; Guanine; Hydrogen Bonding; Methylation; Microscopy, Scanning Tunneling; Nanostructures | 2011 |
Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene.
Topics: Animals; Blotting, Western; Butadienes; Carcinogens, Environmental; DNA Adducts; DNA Methylation; Epigenesis, Genetic; Gene Expression; Genetic Markers; Guanine; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
A freeze frame view of vesicular stomatitis virus transcription defines a minimal length of RNA for 5' processing.
Topics: 5' Flanking Region; Animals; Cells, Cultured; Guanine; Methylation; Nucleocapsid; Organisms, Genetically Modified; Ribose; RNA Caps; RNA-Dependent RNA Polymerase; RNA, Messenger; RNA, Viral; Spodoptera; Transcription, Genetic; Uridine Triphosphate; Vesicular Stomatitis; Vesiculovirus; Viral Nonstructural Proteins; Viral Proteins; Virus Replication | 2011 |
The removal of alkylation products from the DNA of Escherichia coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects.
Topics: Adenine; Alkylating Agents; Alkylation; Carcinogens; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Methylation; Methylnitrosourea | 1980 |
Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression.
Topics: Acetylation; Adenine; Azacitidine; B-Lymphocytes; Cell Line; Chromatin; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Escherichia coli; Gene Expression Regulation; Genotype; Guanine; Histone Deacetylase Inhibitors; Histones; Humans; Interleukin-10; Lipopolysaccharides; Methylation; Polymorphism, Genetic; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic | 2012 |
Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.
Topics: Guanine; Methylation; Methyltransferases; Protein Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Ribosomal, 18S; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; tRNA Methyltransferases | 2012 |
Decaffeination and measurement of caffeine content by addicted Escherichia coli with a refactored N-demethylation operon from Pseudomonas putida CBB5.
Topics: Bacterial Proteins; Beverages; Biosensing Techniques; Caffeine; Escherichia coli; Genome, Bacterial; Glutathione Transferase; Guanine; Methylation; Multigene Family; Operon; Plasmids; Pseudomonas putida; Xanthine; Xanthines | 2013 |
Mapping structurally defined guanine oxidation products along DNA duplexes: influence of local sequence context and endogenous cytosine methylation.
Topics: Amino Acid Sequence; Cytosine; DNA; Guanine; Methylation; Nucleic Acid Conformation; Oxidation-Reduction; Tumor Suppressor Protein p53 | 2014 |
Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA.
Topics: Adenosine; Animals; Binding Sites; Guanine; Methylation; Models, Molecular; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Rats; RNA; RNA-Binding Proteins; Serine-Arginine Splicing Factors | 2014 |
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Binding Sites; Biocatalysis; Crystallography, X-Ray; Escherichia coli Proteins; Guanine; Haemophilus influenzae; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; RNA, Transfer; S-Adenosylmethionine; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; tRNA Methyltransferases | 2015 |
Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
Topics: Base Sequence; Chromosomes, Human, Pair 15; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Epithelial Cells; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanine; Humans; Longitudinal Studies; Lung Neoplasms; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Polymorphism, Single Nucleotide; Smoking; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2015 |
RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithromycin susceptibility.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Guanine; Ketolides; Methylation; Methyltransferases; RNA, Ribosomal, 23S; Streptococcus pneumoniae; Uridine | 2015 |
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.
Topics: Dictyostelium; DNA (Cytosine-5-)-Methyltransferases; Guanine; Methylation; Micronutrients; Pentosyltransferases; RNA, Transfer; RNA, Transfer, Asp; Schizosaccharomyces; Schizosaccharomyces pombe Proteins | 2015 |
Computational study of the reactivity of cytosine derivatives.
Topics: Base Pairing; Cytosine; DNA; DNA Methylation; Gases; Guanine; Hydrogen Bonding; Methylation; Models, Molecular; Quantum Theory; Solutions; Thermodynamics | 2017 |
IPPP-CLOPPA Analysis of the Influence of the Methylation on the Potential Energy and the Molecular Polarizability of the Hydrogen Bonds in the Cytosine-Guanine Base Pair.
Topics: Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Methylation; Quantum Theory | 2017 |
Detecting RNA base methylations in single cells by in situ hybridization.
Topics: Adenine; Escherichia coli; Escherichia coli Proteins; Guanine; In Situ Hybridization, Fluorescence; Methylation; Methyltransferases; Microscopy, Fluorescence; RNA; RNA, Ribosomal; Single-Cell Analysis; Uridine | 2018 |
Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation.
Topics: Arabidopsis Proteins; CpG Islands; DNA; DNA Methylation; Enzymes; Epigenesis, Genetic; Genome; Guanine; Humans; Magnetic Resonance Spectroscopy; Methylation; Molecular Dynamics Simulation; Nuclear Proteins; Oxidative Stress; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Temperature; Thermodynamics | 2018 |
Methylation status of the stimulator of interferon genes promoter in patients with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Biomarkers; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Leukocytes, Mononuclear; Male; Methylation; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Sustained Virologic Response | 2018 |
Queuine links translational control in eukaryotes to a micronutrient from bacteria.
Topics: Animals; Anticodon; Asparagine; DNA (Cytosine-5-)-Methyltransferases; DNA, Mitochondrial; Eukaryota; Guanine; Methylation; Mice; Micronutrients; Protein Biosynthesis; Ribosomes; RNA, Transfer; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine | 2019 |
Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study.
Topics: Acrylamide; Adenine; Administration, Oral; Animals; Carcinogens; DNA Adducts; Epigenesis, Genetic; Female; Guanine; Histones; Liver; Lung; Methylation; Mice; Mutagens; Water Pollutants, Chemical | 2019 |
Interspecies association mapping links reduced CG to TG substitution rates to the loss of gene-body methylation.
Topics: Brassicaceae; Chromosome Mapping; Cytosine; Genetic Association Studies; Genome, Plant; Genomics; Guanine; Methylation; Nucleotides; Phylogeny; Quantitative Trait Loci; Thymine | 2019 |
Cationic guanine: positively charged nucleobase with improved DNA affinity inhibits self-duplex formation.
Topics: Binding Sites; Cations; DNA; Guanine; Methylation; Peptide Nucleic Acids; Static Electricity | 2020 |
Analysis of mitochondrial m1A/G RNA modification reveals links to nuclear genetic variants and associated disease processes.
Topics: Adenosine; ATP-Dependent Proteases; Cell Nucleus; Databases, Genetic; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanine; Humans; Methylation; Mitochondria; Mitochondrial Proteins; Mutation, Missense; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Ribonuclease P; RNA Processing, Post-Transcriptional; RNA-Seq; RNA, Mitochondrial; tRNA Methyltransferases | 2020 |
Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Exoribonucleases; Gene Expression; Guanine; Immunity, Innate; Interferon Lambda; Interferon Type I; Interferons; Methylation; Mutation; Porcine epidemic diarrhea virus; RNA Caps; RNA, Viral; S-Adenosylmethionine; Swine; Vero Cells; Viral Nonstructural Proteins; Virus Replication | 2020 |
Site-specific RNA methylation by a methyltransferase ribozyme.
Topics: Adenosine; Base Sequence; Biocatalysis; Guanine; Methylation; Methyltransferases; Plasmids; RNA, Catalytic; RNA, Transfer; S-Adenosylmethionine | 2020 |
Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator.
Topics: Animals; Entamoeba histolytica; Female; Guanine; HeLa Cells; Humans; Methylation; Mice; Mice, Inbred BALB C; Oxidative Stress; RNA, Transfer | 2021 |
Influence of the Number, Nature and Position of Methyl Posttranscriptional Modifications on Nucleobase Stacking in RNA.
Topics: Adenine; Cytosine; Density Functional Theory; Dimerization; Guanine; Methylation; RNA; RNA Processing, Post-Transcriptional; Uracil | 2021 |
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
Topics: Animals; COVID-19; Guanine; Humans; Immunity, Innate; Interferon Type I; Methylation; Methyltransferases; Mice; Murine hepatitis virus; RNA Caps; RNA, Viral; SARS-CoV-2; Viral Nonstructural Proteins; Virulence; Virus Replication | 2022 |
Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine-
Topics: Guanine; Methylation; Methyltransferases; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Val; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; tRNA Methyltransferases | 2022 |
Non-invasive prediction of p53 and Ki-67 labelling indices and O-6-methylguanine-DNA methyltransferase promoter methylation status in adult patients with isocitrate dehydrogenase wild-type glioblastomas using diffusion-weighted imaging and dynamic suscept
Topics: Adult; Brain Neoplasms; DNA; Glioblastoma; Guanine; Humans; Isocitrate Dehydrogenase; Ki-67 Antigen; Magnetic Resonance Imaging; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Perfusion; Retrospective Studies; Tumor Suppressor Protein p53 | 2022 |
Sequence-specific targeting of RNA.
Topics: Adenosine; Guanine; Methylation; Methyltransferases; RNA | 2022 |