isomethyleugenol has been researched along with folic acid in 333 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (27.63) | 18.7374 |
| 1990's | 48 (14.41) | 18.2507 |
| 2000's | 84 (25.23) | 29.6817 |
| 2010's | 87 (26.13) | 24.3611 |
| 2020's | 22 (6.61) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, AJ | 1 |
| Strum, WB | 1 |
| Benesh, FC; Carl, GF | 1 |
| Campbell, C; Hillman, RS; McGuffin, R | 1 |
| Laborit, H | 1 |
| Friedhoff, AJ; Rosengarten, H | 1 |
| Delk, AS; Rabinowitz, JC | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH | 1 |
| Baldessarini, RJ | 1 |
| Dencker, H; Jägerstad, M; Westesson, AK | 1 |
| Foster, JD; Krall, JA; Lee, HC; Rosenberry, TL; Selhub, J; Shoda, R | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 2 |
| Carl, GF; Eto, I; Furman, GM; Krumdieck, CL; Schatz, RA; Smith, ML | 1 |
| Smith, JT; Zorn, NE | 1 |
| Carney, MW | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Carl, GF | 1 |
| Shane, B; Stokstad, EL | 1 |
| Billings, RE; Hansen, DK | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 2 |
| Leeming, RJ; Melikian, V; Paton, A; Portman-Graham, H | 1 |
| Frisell, WR; Randolph, VM | 1 |
| Chanarin, I; Perry, J | 1 |
| Baker, H; Frank, O | 1 |
| Cossins, EA; Lor, KL | 1 |
| Valencia, R | 1 |
| Hanna, ML; Taylor, RT | 2 |
| Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
| Laduron, P | 2 |
| Freeman, JM; Mudd, SH | 1 |
| Mulherkar, L; Telang, NT | 1 |
| Banerjee, SP; Snyder, SH | 1 |
| Sakai, TT; Santi, DV | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Grossowicz, N; Izak, G; Rachmilewitz, M | 1 |
| Gardyna, HA; Tajuddin, M | 1 |
| Bhuyan, BK; Corrocher, R; Hoffbrand, AV | 1 |
| Shaw, W | 1 |
| Brin, H; Grossowicz, N; Selhub, J | 1 |
| Bouveng, R | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Brewer, CF; Santi, DV | 1 |
| Neumann, H; Rosenberg, IH | 1 |
| Taylor, RT; Weissbach, H | 4 |
| Luckner, M | 1 |
| Burton, E; Sakami, W; Selhub, J | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Crusberg, TC; Kisliuk, RL; Leary, R | 1 |
| Bertino, JR; Nixon, PF | 2 |
| Rüdiger, H | 1 |
| Taylor, RT | 2 |
| Baugh, CM; Butterworth, CE; Krumdieck, C | 1 |
| Cossins, EA; Dodd, WA | 1 |
| Baker, HJ; Baugh, CM; Butterworth, CE; Krumdieck, CL | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH; Shih, VE; Uhlendorf, BW | 1 |
| Draper, MW; Mangum, JH; North, JA | 1 |
| Barness, LA; Morrow, G | 1 |
| Goldman, ID | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 2 |
| Ghambeer, RK; Ljungdahl, L; Schulman, M; Wood, HG | 1 |
| Mahoney, MJ; Mudd, SH; Rosenberg, LE; Uhlendorf, BW | 1 |
| Foster, MA; Salem, AR; Wilson, RH | 1 |
| Fujii, K; Fukui, S | 1 |
| Dreyfus, PM | 1 |
| Dunlap, RB; Harding, NG; Huennekens, FM | 1 |
| Sovik, O | 1 |
| Semonský, M; Slavík, K; Slavíková, V; Volejníková, J; Zikán, V | 1 |
| Burton, EG; Sakami, W | 1 |
| Drais, JH; Huennekens, FM; Whiteley, JM | 1 |
| Barr, FE | 1 |
| Dinn, JJ; McCann, S; Reed, B; Scott, JM; Weir, DG; Wilson, P | 1 |
| Gerisch, G | 1 |
| Howard-Peebles, PN; Krumdieck, CL | 1 |
| Smythies, JR | 1 |
| Deacon, R; Lumb, MJ; Perry, J | 1 |
| Chanarin, I | 1 |
| Akesson, B; Fehling, C; Jägerstad, M | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Bunduki, V; Dommergues, M; Dumez, Y; Marquet, J; Muller, F; Zittoun, J | 1 |
| Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D | 1 |
| Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Scott, JM; Weir, DG | 1 |
| Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ | 1 |
| Boers, GH; Janssen, MJ; Stehouwer, CD; van den Berg, M | 1 |
| Chaves, P; Cravo, M; Fidalgo, P; Gouveia-Oliveira, A; Leitao, CN; Mason, JB; Mira, FC; Pereira, AD; Selhub, J | 1 |
| Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM | 1 |
| Ragel, C; Ruiz-Roso, B; Varela-Moreiras, G | 1 |
| Christensen, B; Ueland, PM | 1 |
| Barkhof, F; Braam, M; Frequin, ST; Hommes, OR; Wevers, RA | 1 |
| Dolnick, BJ; Hsueh, CT | 1 |
| Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E | 1 |
| Colditz, GA; Giovannucci, E; Rimm, EB; Rosner, BA; Speizer, FE; Stampfer, MJ; Trichopoulos, D; Willett, WC | 1 |
| Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G | 1 |
| Allen, RH; Buring, JE; Gaziano, JM; Hennekens, CH; Kok, FJ; Reynolds, RD; Stabler, SP; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Broom, AD; Francom, P; Gangjee, A; Queener, SF; Zhu, Y | 1 |
| Christensen, B | 1 |
| Maclennan, R; Nixon, P; Seitz, HK; Watson, RR | 1 |
| Gottfries, CG; Regland, B; Smythies, JR | 1 |
| Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH | 1 |
| Bottiglieri, T | 2 |
| Boiocchi, M; Corona, G; Donada, C; Fabris, M; Toffoli, G; Viel, A; Zarrelli, A | 1 |
| Fiskerstrand, T; Refsum, H; Ueland, PM | 1 |
| De Santo, NG; Ingrosso, D; Perna, AF | 1 |
| Aubard, Y; Baudet, JH; Chinchilla, AM; Piver, P | 1 |
| Daly, S; Scott, JM | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Eskes, TK | 1 |
| Boddie, AM; Dembure, PP; Elsas, LJ; Fisher, AJ; Macmahon, W; Saxe, D; Steen, MT; Sullivan, KM | 1 |
| Bodennec, J; Brichon, G; Koul, O; Portoukalian, J; Zwingelstein, G | 1 |
| Liu, Y; Santi, DV | 1 |
| Cattaneo, M | 1 |
| Achón, M; Alonso-Aperte, E; Pérez-Miguelsanz, J; Ubeda, N; Varela-Moreiras, G | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Albanes, D; Hartman, TJ; Nieto, FJ; Rautalahti, M; Sehlub, J; Stolzenberg-Solomon, RZ; Tangrea, JA; Taylor, PR; Virtamo, J | 1 |
| Mills, JL | 1 |
| Dudman, NP; Elsworth, GR; Guo, XW; Kelly, FD; Li, D; Mann, NJ; Sinclair, AJ; Wilson, AK | 1 |
| Achón, M; Alonso-Aperte, E; Reyes, L; Ubeda, N; Varela-Moreiras, G | 1 |
| Scott, JM; Weir, DG | 1 |
| Ash, C; Gallinger, S; Kim, YI; Medline, A; Sohn, KJ; Song, J | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| Law, MR; Wald, NJ | 1 |
| Rozen, R | 1 |
| Cook, RJ | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Shane, B; Stacpoole, PW; Toth, JP | 1 |
| Stam, F; Stehouwer, CD; van Guldener, C | 1 |
| Graf, WD; Oleinik, OE | 1 |
| Castaldo, P; Cimmino, A; De Santo, NG; di Carlo, E; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Freedman, AN; Ishibe, N | 1 |
| Daskalakis, I; Hinkins, M; Lucock, M; Yates, Z | 1 |
| Chen, Y; Deth, RC; Malewicz, B; Rosowsky, A; Sharma, A; Stover, P; Tan, W; Waly, M; Zhao, R | 1 |
| Finnell, RH; Gelineau-van Waes, J | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Fohr, I; Pietrzik, K; Prinz-Langenohl, R | 1 |
| Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K | 1 |
| Bagley, PJ; Jacques, PF; Kalmbach, R; Rogers, G; Rosenberg, IH; Russo, GT; Selhub, J; Wilson, PW | 1 |
| Matthews, RG | 1 |
| Díaz, M; Freixas, E; Schiel, A; Trimarchi, H | 1 |
| Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
| Chiang, EP; Herbig, K; Hills, J; Lee, LR; Shane, B; Stover, PJ | 1 |
| Coetzee, GA; Laird, PW; Ong, CN; Trinh, BN; Yu, MC | 1 |
| de Meer, K; Finglas, P; Smulders, Y; Stam, F; Stehouwer, CD; van den Akker, JT | 1 |
| Zhu, BT | 1 |
| Mattson, MP; Shea, TB | 1 |
| Mason, JB | 1 |
| Beilin, LJ; Burke, V; Croft, KD; Hodgson, JM; Puddey, IB | 1 |
| Lökk, J | 1 |
| Bagley, PJ; Lathrop Stern, L; Nadeau, M; Selhub, J; Shane, B; Shih, V | 1 |
| FATTERPAKER, P; MARFATIA, U; SREENIVASAN, A | 1 |
| SAKAMI, W; UKSTINS, I | 1 |
| OERIU, S; TANASE, I | 2 |
| ELISON, C; ELLIOTT, HW | 1 |
| Albanes, D; Glynn, SA | 1 |
| Bailey, LB; Coats, BS; Davis, SR; Gregory, JF; Kick, LS; Quinlivan, EP; Shane, B; Stacpoole, PW; Williamson, J | 1 |
| Bailey, LB | 1 |
| Chen, Z; Ghandour, H; Rozen, R; Selhub, J | 1 |
| Kelly, TL; Neaga, OR; Rozen, R; Schwahn, BC; Trasler, JM | 1 |
| de Meer, K; Jakobs, C; Stam, F; Stehouwer, CD; Ter Wee, PM; van Guldener, C | 1 |
| de Meer, K; Jakobs, C; Smulders, YM; Stam, F; Stehouwer, CD; van Guldener, C | 1 |
| Choi, SW; Corrocher, R; Friso, S; Girelli, D; Guarini, P; Olivieri, O; Pignatti, PF; Trabetti, E | 1 |
| Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C | 1 |
| Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
| Blasco, C; Caballería, J; Deulofeu, R; Gual, A; Lligoña, A; Lluis, JM; Parés, A; Rodés, J | 1 |
| Smulders, YM; Stehouwer, CD | 1 |
| Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
| Bjorklund, NK; Gordon, R | 1 |
| Kumar, A; Mehta, S; Pandey, LK; Rai, AK; Raman, R; Singh, S | 1 |
| Bambara, LM; De Franceschi, L; Guarini, P; Scambi, C | 1 |
| Loscalzo, J | 1 |
| Toohey, JI | 1 |
| Hsiung, D; Kelsey, KT; Kraunz, KS; Liu, M; McClean, MD; Nelson, HH; Osanyingbemi, J | 1 |
| Burren, KA; Chitty, LS; Copp, AJ; Dunlevy, LP; Greene, ND | 1 |
| Maloney, CA; Rees, WD; Wilson, FA | 1 |
| Botha, J; Erasmus, RT; Haug, P; Hendricks, M; Hon, D; Kotze, MJ; Kuyler, J; Matsha, T; Potocnik, FC; van Rensburg, SJ | 1 |
| Blom, HJ; den Heijer, M; Finnell, RH; Shaw, GM | 1 |
| Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Blouet, C; Daré, S; Hammiche, A; Huneau, JF; Mariotti, F; Tomé, D | 1 |
| Ahsan, H; Chen, Y; Factor-Litvak, P; Gamble, MV; Graziano, JH; Ilievski, V; Levy, D; Liu, X; Parvez, F; Pilsner, JR; Slavkovich, V | 1 |
| Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R | 1 |
| Burke, V; Hodgson, JM; Puddey, IB; van Bockxmeer, FM | 1 |
| Benevenga, NJ | 1 |
| Burren, KA; Chitty, LS; Copp, AJ; Doudney, K; Dunlevy, LP; Greene, ND; Scott, R; Stanier, P; Stojilkovic-Mikic, T | 1 |
| Chen, L; Deng, FR; Guo, XB; Wang, ZQ; Zhang, K | 1 |
| Bendini, MG; Cozzari, L; De Cristofaro, R; Farina, SM; Giordano, A; Giordano, G; Lanza, GA; Leggio, M; Mazza, A; Menichini, G; Moriconi, E | 1 |
| Ahsan, H; Baron, JA; Chen, Y; Gamble, MV; Graziano, JH; Heck, JE; Howe, GR; Parvez, F; Slavkovich, V | 1 |
| Hudson, PR; McCaddon, A | 1 |
| Bodamer, O; Freilinger, M; Haas, O; Kalisch, D; Moritz, A; Muehl, A | 1 |
| Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH | 1 |
| Ahsan, H; Alam, S; Factor-Litvak, P; Gamble, MV; Graziano, JH; Ilievski, V; Islam, M; Levy, D; Liu, X; Parvez, F; Pilsner, JR; Slavkovich, V | 1 |
| Fanghänel, J; Gedrange, T; Maile, S; Proff, P; Weingärtner, J | 1 |
| Chen, CJ; Chung, CJ; Hsueh, YM; Huang, YK; Pu, YS; Shiue, HS; Yang, MH | 1 |
| Ingwall, JS; Tian, R | 1 |
| Kile, ML; Ronnenberg, AG | 1 |
| Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN | 1 |
| Blom, HJ; Burren, KA; Copp, AJ; Greene, ND; Kok, RM; Massa, V; Savery, D; Scott, JM | 1 |
| Bouchard, TP; Camicioli, RM; Somerville, MJ | 1 |
| Becker, A; Bode, U; Jaehde, U; Schüsseler, P; Vezmar, S | 1 |
| Allen, RH; Gao, D; Girnary, HH; MacFarlane, AJ; Perry, CA; Shane, B; Stabler, SP; Stover, PJ | 1 |
| Albrieux, C; Block, MA; De Brouwer, V; Douce, R; Gambonnet, B; Lambert, WE; Loizeau, K; Ravanel, S; Rebeille, F; Van Der Straeten, D; Van Wilder, V | 1 |
| Chen, WW; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Zeisel, SH | 1 |
| Blom, HJ | 1 |
| Cohen, IJ | 1 |
| Freeman, K | 1 |
| Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A | 1 |
| de Jonge, R; de Vries, JH; Eijkemans, MJ; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Meurs, JB | 1 |
| Brustolin, S; Félix, TM; Giugliani, R | 1 |
| Balakrishnan, V; Girish, BN; Rajesh, G; Rao, NA; Reshmi, S; Vaidyanathan, K | 1 |
| Fenech, M | 1 |
| Chen, HW; Chung, CJ; Hsueh, YM; Huang, YK; Pu, YS; Shiue, HS; Su, CT | 1 |
| Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S | 1 |
| Burren, K; Copp, AJ; De Castro, SC; Greene, ND; Leung, KY; Rozen, R; Savery, D | 1 |
| Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN | 1 |
| Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
| Bischof, JM; Boshnjaku, V; Costa, FF; Ichi, S; Mania-Farnell, B; Mayanil, CS; McLone, DG; Nakazaki, H; Sharma, S; Shen, YW; Soares, MB; Tomita, T | 1 |
| de Jonge, R; Helbing, WA; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; Wildhagen, MF | 1 |
| Ekström, EC; Gardner, RM; Grandér, M; Hoque, AM; Kippler, M; Li, L; Lönnerdal, B; Nermell, B; Rahman, A; Vahter, M | 1 |
| El-Saden, S; Hathout, L | 1 |
| Alvarez, RD; Badiga, S; Chen, M; Edberg, JC; Johanning, GL; Macaluso, M; Partridge, EE; Piyathilake, CJ; Siddiqui, NR | 1 |
| Herrmann, M; Herrmann, W; Obeid, R; Schlundt, J; Umanskaya, N | 1 |
| Alberto, JM; Brachet, P; Garcia, MM; Guéant, JL; Guéant-Rodriguez, RM; Gueguen, N; Herrmann, M; Jeannesson, E; Juillière, Y; Lacolley, P; Malthiery, Y; Marie, PY; Maskali, F; Pooya, S | 1 |
| Cinderella, M; Gamble, MV; Hall, MN; Lawley, SD; Nijhout, HF; Reed, MC | 1 |
| Böhlke, M; Broersen, LM; Hageman, RJ; Kamphuis, PJ; Maher, TJ; van Wijk, N; Watkins, CJ; Wurtman, RJ | 1 |
| Molloy, AM | 1 |
| Batra, V; Devasagayam, TP | 1 |
| Kaur, J; Nada, R; Wani, NA | 1 |
| Jin, J; Kung, HF; Lin, MC; Ng, SSM; Poon, WS; Siu, LKS; Sun, H; Sze, J; Xu, Z; Yao, H | 1 |
| Ando, N; Bender, G; Blasiak, LC; Doukov, TI; Drennan, CL; Kung, Y; Ragsdale, SW; Seravalli, J | 1 |
| Anderson, SE; Calder, AG; Holtrop, G; Lobley, GE; Rees, WD; Wilson, FA | 1 |
| Alberto, JM; Blaise, S; Bressenot, A; Bronowicki, JP; Daval, JL; Giudicelli, J; Guéant, JL; Guéant-Rodriguez, RM; Gueguen, N; Jeannesson, E; Malthiery, Y; Moreno Garcia, M; Nicolas, B; Peyrin-Biroulet, L; Pooya, S | 1 |
| Bressenot, A; Bronowicki, JP; Chango, A; Forges, T; Guéant, JL; Namour, F; Pellanda, H | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Halsted, CH; Medici, V | 1 |
| Duncan, TM; Nijhout, HF; Reed, MC | 1 |
| Morris, MS | 1 |
| Bertolo, RF; McBreairty, LE | 1 |
| Burkey, KO; Bush, LP; Conkling, MA; Fan, L; Holliday, BM; Hung, CY; Kittur, FS; Qiu, J; Roje, S; Sun, K; Tang, S; Xiao, B; Xie, J | 1 |
| Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L | 1 |
| Neradil, J; Pavlasova, G; Veselska, R | 1 |
| Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM | 1 |
| Cai, T; He, XJ; Huang, HW; Jiang, L; Ma, ZY; Zhang, C; Zhang, FF; Zhou, HR; Zhu, JK | 1 |
| Joseph, J; Loscalzo, J | 1 |
| Cande, WZ; Guan, Q; Hammond, MC; Iavarone, AT; Li, F; Rine, J; Sadhu, MJ; Sales-Lee, J | 1 |
| Benoist, JF; Blom, HJ; Imbard, A | 1 |
| Briguglio, I; Carta, A; Corona, P; Costi, MP; Ferrari, S; Luciani, R; Paglietti, G; Piras, S | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Gao, Y; Huang, G; Li, W; Liu, H; Luo, S; Wang, X; Wilson, JX; Yu, M; Zhang, Y | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Levy, D; Liu, X; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 2 |
| Barrett, DA; Dainty, JR; Finglas, PM; Hudson, M; Jackson, R; Jones, DE; King, MJ; Patanwala, I; Philo, M; Rose, J; Wright, AJ | 1 |
| Chen, J; Liu, R; Wen, J; Yu, X; Zhao, G; Zheng, M | 1 |
| Helke, KL; Kistner-Griffin, E; Krupenko, NI; Krupenko, SA; Oleinik, NV | 1 |
| Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM | 1 |
| Brachet, P; Comte, B; Deval, C; Jousse, C; Martinez, E; Mazur, A | 1 |
| Cui, S; Huang, G; Jiang, M; Li, W; Xiao, Y; Zhang, X | 1 |
| Best, A; Caudill, MA; Christensen, KE; Deng, L; Greene, ND; Leung, KY; Lévesque, N; Malysheva, OV; Mikael, LG; Rozen, R; Wu, Q | 1 |
| Cirino, G; Di Minno, A; Di Minno, G; Franchini, M; Lupoli, R; Sorrentino, R; Spadarella, G | 1 |
| Balac, O; Factor-Litvak, P; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Mey, JL; Parvez, F; Peters, BA; Sanchez, TR; Shahriar, H; Siddique, AB; Uddin, MN; van Geen, A | 1 |
| Kang, P; Li, Z; Niu, Q; Ren, P; Yang, X; Yuan, Y | 1 |
| Locasale, JW; Mentch, SJ | 1 |
| Bertolo, RF; Robinson, JL | 1 |
| Blanco, R; Colombo, A; Pardo, R; Suazo, J | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; Randell, EW; Robinson, JL | 1 |
| Assaraf, YG; Raz, S; Stark, M | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Greene, NDE; Ho, MK; Jadavji, NM; Kaliman, P; Leung, KY; Lu, J; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Bagga, R; Hamid, A; Kaur, J; Mahajan, A; Rahat, B | 1 |
| Becker, L; Ehninger, D; Ehninger, G; Fuchs, H; Gailus-Durner, V; Garrett, L; Guo, L; Henzel, KS; Hölter, SM; Hrabě de Angelis, M; Klingenspor, M; Klopstock, T; Müller, R; Neff, F; Paesler, K; Papazoglou, A; Pearson, BL; Rácz, I; Rathkolb, B; Rozman, J; Ryan, DP; Schröder, S; Sidiropoulou, K; Siwek, ME; Weiergräber, M; Wolf, E; Wurst, W; Xie, K; Yu, M; Zhou, Y; Zimmer, A | 1 |
| Gao, Y; Huang, G; Li, M; Liu, H; Zheng, M; Zou, C | 1 |
| Finnell, RH; Toriyama, M; Wallingford, JB | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Couce, ML; Llarena, M; López-Suárez, O | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Ducker, GS; Gitai, Z; Li, SH; Mayer, JA; Morscher, RJ; Rabinowitz, JD; Sperl, W | 1 |
| Kasulanati, S; Venkatesan, V | 1 |
| Carrillo, G; Power, MC; Taylor, BD; Xu, X; Zhang, X; Zhong, Y | 1 |
| Barg, G; Desai, G; Kordas, K; Mañay, N; Peregalli, F; Queirolo, EI; Vahter, M | 1 |
| Birner-Gruenberger, R; Schittmayer, M; Zamboni, N | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Fry, RC; Gamble, MV; Garcia-Vargas, G; Herring, AH; Ilievski, V; Laine, JE; Richardson, DB; Rubio-Andrade, M; Stýblo, M | 1 |
| Chakraborty, A; Chang, CC; Chang, YS; Chen, TW; Chen, YT; Cheng, ML; Chien, KY; Hsieh, YJ; Huang, SC; Lee, YH; Lin, TY; Lin, WC; Lin, YT; Liu, JL; Luo, JD; Pai, LM; Shiao, MS; Sung, LY; Tang, HY; Tung, CS; Wang, PY; Yeh, CT; Yu, JS | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Chiang, AJ; Gugiu, GB; Hu, W; Kalkum, M; Morra, CN; Röth, D; Versalovic, J | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R | 1 |
| Ahsan, H; Argos, M; Dean, S; Gamble, MV; Graziano, JH; Islam, MT; Islam, T; Jasmine, F; Kibriya, MG; Lynch, VJ; Oglesbee, D; Pierce, BL; Rahman, M; Rakibuz-Zaman, M; Sarwar, G; Shahriar, H; Tong, L; Yunus, M | 1 |
| Belardo, A; Gevi, F; Zolla, L | 1 |
| Jadavji, NM; Murray, LK | 1 |
| Behrman, EJ; Krzycki, JA; Picking, JW; Zhang, L | 1 |
| DiNicolantonio, JJ; McCarty, MF; O'Keefe, JH | 1 |
| Ao, PL; Chung, CJ; Hsieh, RL; Hsueh, YM; Huang, PT; Huang, SR; Huang, YL; Lin, MI; Lin, YC; Mu, SC; Shiue, HS; Su, CT; Wu, MY | 1 |
| Du, B; Godfrey, O; Huang, X; Li, D; Ren, B; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Julien, A; Pourié, G; Robert, A; Saber Cherif, L; Umoret, R | 1 |
| Guo, S; Huang, W; Jin, Z; Liu, Q; Sheng, Y; Wang, Z | 1 |
| Copp, AJ; Greene, N; Leung, KY; Mahmood, MR; Pai, YJ; Santos, C; Savery, D; Waddington, SN | 1 |
| Béven, L; Blanchard, A; Brégeon, D; Crécy-Lagard, V; Douthwaite, S; Goyenvalle, C; Grosjean, H; Hamdane, D; Rose, S; Sirand-Pugnet, P | 1 |
| Chen, X; Huang, X; Li, D; Ren, B; Shi, F; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q; Zheng, C | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
| Browne, RW; Desai, G; Kordas, K; Mañay, N; Millen, AE; Peregalli, F; Queirolo, EI; Vahter, M; Yu, J | 1 |
| Elango, R | 1 |
| Bouvier, D; Brailova, M; Minet-Quinard, R; Regnier, A; Sapin, V; Szymanowski, M | 1 |
| Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
| Abuawad, A; Bozack, AK; Gamble, MV; Saxena, R | 1 |
| Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E | 1 |
| Arai, T; Chijimatsu, R; Doki, Y; Eguchi, H; Hirotsu, T; Ishii, H; Kitagawa, T; Ofusa, K; Takeda, Y; Vecchione, A; Yabumoto, M | 1 |
| Lee, SK | 1 |
| Ghergurovich, JM; Rabinowitz, JD; Ryseck, RP; Wang, JZ; Wang, L; Xu, X; Yang, L | 1 |
| Cheng, Y; Huang, Z; Lv, Z; Shi, F; Wei, Q; Ye, N | 1 |
| Clement, P; Elder, K; Menezo, Y | 1 |
| Fustin, JM | 1 |
| Guo, P; Lan, T; Liang, H; Wang, Y; Xue, M; Zhang, H; Zhao, H; Zuo, Y | 1 |
| Broz, P; Racek, J; Rajdl, D; Stehlík, P; Trefil, L | 1 |
| Bommarito, P; Clark, J; Fry, RC; Gamble, MV; García-Vargas, GG; Rubio-Andrade, M; Stýblo, M | 1 |
| Fogle, HM; Krupenko, NI; Krupenko, SA; McCormac, JP; Molina, S; Rushing, BR; Sharma, J; Sumner, S; You, M | 1 |
| Bernardin, F; Burt-Oberecken, N; Dimofski, P; Dreumont, N; Guéant, JL; Kaoma, T; Lambert, L; Laugeais, E; Leheup, B; Leininger-Muller, B; Mosca, P; Renaud, M; Vallar, L; Willekens, J | 1 |
71 review(s) available for isomethyleugenol and folic acid
| Article | Year |
|---|---|
Commentary: The roles of folate and pteridine derivatives in neurotransmitter metabolism.
Topics: Animals; Biogenic Amines; Brain; Folic Acid; Glycine; Humans; In Vitro Techniques; Mental Disorders; Methylation; Neurotransmitter Agents; Pteridines; Pterins; Subcellular Fractions | 1977 |
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
A review of recent studies of the biosynthesis and excretion of hallucinogens formed by methylation of neurotransmitters or related substances.
Topics: Alcohol Oxidoreductases; Bufotenin; Carbolines; Dimethoxyphenylethylamine; Dopamine; Ethylamines; Folic Acid; Hallucinogens; Humans; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Norepinephrine; S-Adenosylmethionine; Schizophrenia; Serotonin; Tryptamines | 1976 |
Cobalamin and folate: recent developments.
Topics: Anemia, Megaloblastic; Female; Folic Acid; Humans; Methylation; Methylmalonic Acid; Nervous System Diseases; Neural Tube Defects; Nitrous Oxide; Vitamin B 12 Deficiency | 1992 |
Neuropharmacology of S-adenosyl methionine.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Folic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Methionine Adenosyltransferase; Methylation; Nervous System Diseases; Phospholipids; Proteins; Rats; S-Adenosylmethionine; Schizophrenia; Synapses; Synaptic Transmission | 1986 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
[Control of cellular division by vitamin B 12 and folates].
Topics: Anemia, Macrocytic; Anemia, Pernicious; Animals; Cell Division; Euglena gracilis; Folic Acid; Folic Acid Deficiency; Humans; Leukemia; Methylation; Nucleic Acids; Nucleotides; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Intestinal absorption of folates.
Topics: Animals; Carbon Isotopes; Dogs; Folic Acid; Food Analysis; Glutamates; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Methylation; Peptides; Structure-Activity Relationship | 1972 |
[On new studies of the biosynthesis of N-heterocyclic compounds. 5. Formation and decomposition of substances with purine, pteridine, and benzopteridine ring systems].
Topics: Allantoin; Caffeine; Folic Acid; Heterocyclic Compounds; Methylation; Oxidation-Reduction; Pteridines; Purines; Pyrimidines; Theobromine | 1966 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Chemotaxis in Dictyostelium.
Topics: Chemotactic Factors; Chemotaxis; Cyclic AMP; Dictyostelium; Folic Acid; Methylation; Myosins; Phospholipids | 1982 |
Vitamin B12, folate and nitrous oxide.
Topics: Anemia, Megaloblastic; Animals; Deoxyuridine; Folic Acid; Formates; Hematopoiesis; Humans; Methylation; Nitrous Oxide; Vitamin B 12 | 1982 |
Nitrous oxide and the cobalamins.
Topics: Anesthesia, Inhalation; Animals; Chemical Phenomena; Chemistry; Coenzymes; Deoxyuridine; Folic Acid; Humans; Liver; Methylation; Nervous System; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Vitamin B 12 | 1980 |
Hyperhomocysteinaemia: a role in the accelerated atherogenesis of chronic renal failure?
Topics: Adult; Age Factors; Arteriosclerosis; Cystathionine beta-Synthase; Cysteine; Female; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Humans; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Sex Factors | 1995 |
Folate, alcohol, methionine, and colon cancer risk: is there a unifying theme?
Topics: Alcohol Drinking; Animals; Colonic Neoplasms; DNA; Ethanol; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Risk Factors; S-Adenosylmethionine | 1994 |
[Folate deficiency, cancer and congenital abnormalities. Is there a connection?].
Topics: Adult; Congenital Abnormalities; DNA; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Methylation; Neoplasms; Pregnancy | 1996 |
Alcohol and cancer.
Topics: Animals; Carcinogens; Epidemiologic Factors; Esophageal Neoplasms; Ethanol; Folic Acid; Humans; Methylation; Mice; Murine Acquired Immunodeficiency Syndrome; Neoplasms; Vitamin E | 1994 |
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia | 1997 |
Folate, vitamin B12, and neuropsychiatric disorders.
Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Adverse effects of hyperhomocysteinemia and their management by folic acid.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Methylation; Risk Factors; Uremia | 1997 |
[Folates and the neural tube. Review of the literature].
Topics: Animals; Europe; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methionine; Methylation; Neural Crest; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care; Prevalence; Risk Factors | 1997 |
The prevention of neural tube defects.
Topics: Female; Folic Acid; Food, Fortified; Humans; Mass Screening; Methylation; Neural Tube Defects; Pregnancy; Risk | 1998 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Neural tube defects, vitamins and homocysteine.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Rats; Spinal Dysraphism | 1998 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
Folate and oral clefts: where do we go from here? New directions in oral clefts research.
Topics: Cleft Lip; Cleft Palate; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Infant, Newborn; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 1999 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Homocysteine and ischaemic heart disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies | 1999 |
Genetic modulation of homocysteinemia.
Topics: Amino Acid Substitution; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Sulfur; Tetrahydrofolates | 2000 |
Homocysteine metabolism in renal failure.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases | 2001 |
The study of neural tube defects after the Human Genome Project and folic acid fortification of foods.
Topics: Animals; Folic Acid; Food, Fortified; Gene Expression Regulation, Developmental; Genetic Heterogeneity; Human Genome Project; Humans; Methylation; Mice; Neural Tube Defects | 2000 |
Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Dietary Fiber; Environmental Exposure; Enzyme Inhibitors; Folic Acid; Genes, APC; Genes, bcl-2; Genes, DCC; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Microtubule-Associated Proteins; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Smoking; Tumor Suppressor Proteins | 2001 |
Genetics of neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Double-Blind Method; Female; Folic Acid; Humans; Infant, Newborn; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Placebos; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Transcription Factors; Vitamins | 2001 |
Beneficial role for folate in the prevention of colorectal and breast cancer.
Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Methylation; Prospective Studies; Risk Factors | 2001 |
Methylenetetrahydrofolate reductase: a common human polymorphism and its biochemical implications.
Topics: Amino Acid Substitution; Animals; Catalysis; Folic Acid; Humans; Kinetics; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic | 2002 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism.
Topics: Biomarkers; Carbon; Diet; DNA Methylation; Folic Acid; Homocysteine; Humans; Methylation; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2003 |
News and views on folate and elderly persons.
Topics: Aged; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mental Disorders; Methylation; Neoplasms; Risk Factors; Vitamin B 12 Deficiency | 2003 |
Folate and cancer: a review of the literature.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neoplasms; Risk Factors | 1994 |
Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations.
Topics: Adenoma; Alcohol Drinking; Colonic Neoplasms; Folic Acid; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Neoplasms; Nutrition Policy; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12 | 2003 |
Folate metabolism and cardiovascular disease.
Topics: Biomarkers; Cardiovascular Diseases; DNA; Folic Acid; Homocysteine; Humans; Methylation; Risk Factors | 2005 |
Homocysteine and folate metabolism in depression.
Topics: Animals; Depression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Neurotransmitter Agents; Vitamin B 12 Deficiency | 2005 |
A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations of the cytoskeleton.
Topics: Animals; Cytoskeletal Proteins; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neural Tube Defects; Protein Processing, Post-Translational | 2006 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Neural tube defects and folate: case far from closed.
Topics: Animals; Central Nervous System; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects | 2006 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Can folate intake reduce arsenic toxicity?
Topics: Arsenic; Arsenic Poisoning; Environmental Exposure; Folic Acid; Humans; Methylation; Neoplasms; Risk Factors; Vitamin B Complex | 2008 |
Importance of methyl donors during reproduction.
Topics: Brain; Choline; Female; Fetal Development; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Methylation; Neural Tube Defects; Nootropic Agents; Nutritional Requirements; Pregnancy; Prenatal Nutritional Physiological Phenomena; Vitamin B Complex | 2009 |
Folic acid, methylation and neural tube closure in humans.
Topics: Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Metabolic Networks and Pathways; Methylation; Methyltransferases; Models, Biological; Neural Tube; Neural Tube Defects; Pregnancy | 2009 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
Nitrous oxide-induced B₁₂ deficiency myelopathy: Perspectives on the clinical biochemistry of vitamin B₁₂.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cobamides; Cytokines; Folic Acid; Gait Ataxia; Humans; Illicit Drugs; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Imaging; Male; Methylation; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Models, Animal; Models, Biological; Nitrous Oxide; Postgastrectomy Syndromes; Pyramidal Tracts; Spinal Cord; Subacute Combined Degeneration; Substance-Related Disorders; Vitamin B 12; Young Adult | 2011 |
Genetic aspects of folate metabolism.
Topics: Animals; Coenzymes; DNA; DNA Repair; Female; Folic Acid; Humans; Metabolic Networks and Pathways; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy | 2012 |
Folate, alcohol, and liver disease.
Topics: Absorption; Alcohol Drinking; Animals; Antioxidants; Disease Models, Animal; Epigenesis, Genetic; Ethanol; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Intestine, Small; Liver; Liver Diseases, Alcoholic; Methionine; Methylation | 2013 |
The role of B vitamins in preventing and treating cognitive impairment and decline.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2012 |
The nutritional burden of methylation reactions.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines | 2013 |
New mechanisms for an old drug; DHFR- and non-DHFR-mediated effects of methotrexate in cancer cells.
Topics: Antimetabolites, Antineoplastic; Cell Death; Cell Differentiation; Folic Acid; Folic Acid Antagonists; Histone Deacetylase Inhibitors; Humans; Methotrexate; Methylation; Nucleotides; Tetrahydrofolate Dehydrogenase | 2012 |
Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology.
Topics: Cardiovascular Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Oxidation-Reduction; Randomized Controlled Trials as Topic; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 2013 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
Methylation reactions, the redox balance and atherothrombosis: the search for a link with hydrogen sulfide.
Topics: Animals; Aspirin; Atherosclerosis; Folic Acid; Gasotransmitters; Homocysteine; Humans; Hydrogen Sulfide; Methionine; Methylation; Oxidation-Reduction; Thrombosis | 2015 |
One-carbon metabolism and epigenetics: understanding the specificity.
Topics: Animals; Chromatin; Epigenesis, Genetic; Epigenomics; Folic Acid; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; S-Adenosylmethionine; Substrate Specificity | 2016 |
The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands.
Topics: Amino Acids; Betaine; Diet; DNA Methylation; Folic Acid; Humans; Methionine; Methylation; Neonatology; Nutritional Requirements; Phosphatidylcholines; Protein Biosynthesis | 2016 |
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis.
Topics: Biomarkers; Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Vitamin B 12 | 2016 |
Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Methylation; Mice; Neoplasms; Peptide Synthases; Polyglutamic Acid; S-Adenosylmethionine; Signal Transduction | 2016 |
The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms.
Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex | 2019 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Nutrition, one-carbon metabolism and arsenic methylation.
Topics: Animals; Arsenic; Carbon; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Food; Humans; Methylation; Nutritional Status; Observational Studies as Topic; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer.
Topics: Animals; Carbon; Cell Transformation, Neoplastic; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylation; Mitochondria; Reactive Oxygen Species; RNA | 2021 |
17 trial(s) available for isomethyleugenol and folic acid
| Article | Year |
|---|---|
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors | 1995 |
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation.
Topics: Adenoma; Adult; Aged; Biomarkers, Tumor; Carcinoma; Colorectal Neoplasms; DNA; Female; Folic Acid; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Methylation; Middle Aged; Prospective Studies | 1994 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Randomized trial of methylcobalamin and folate effects on homocysteine in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2002 |
Can black tea influence plasma total homocysteine concentrations?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cholesterol; Cross-Over Studies; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Lipids; Male; Methylation; Middle Aged; Phenols; Polymers; Polyphenols; Tea; Vitamin B 12; Vitamin B 6 | 2003 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Creatine; Creatinine; Dietary Supplements; Double-Blind Method; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Skin Neoplasms; Urinary Bladder Neoplasms; Vitamin B Complex; Water Pollutants, Chemical | 2006 |
Folic acid supplementation lowers blood arsenic.
Topics: Arsenic; Arsenicals; Bangladesh; Dietary Supplements; Double-Blind Method; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
Arsenic methylation efficiency increases during the first trimester of pregnancy independent of folate status.
Topics: Adult; Arsenic; Arsenicals; Cacodylic Acid; Environmental Exposure; Female; Folic Acid; Food Contamination; Gestational Age; Humans; Longitudinal Studies; Methylation; Nutritional Status; Pregnancy; Pregnancy Trimester, First; Water | 2011 |
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine.
Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Folic acid handling by the human gut: implications for food fortification and supplementation.
Topics: Administration, Oral; Adult; Biotransformation; Carbon Radioisotopes; Cohort Studies; Cross-Over Studies; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Intestinal Mucosa; Kinetics; Leucovorin; Male; Methylation; Middle Aged; Portal Vein; Portasystemic Shunt, Transjugular Intrahepatic; Tetrahydrofolates | 2014 |
Folic Acid and Creatine as Therapeutic Approaches to Lower Blood Arsenic: A Randomized Controlled Trial.
Topics: Adult; Aged; Arsenic; Bangladesh; Creatine; Creatinine; Dietary Supplements; Drinking Water; Female; Folic Acid; Humans; Male; Methylation; Middle Aged; Water Pollutants, Chemical; Water Purification | 2015 |
Folic acid supplementation enhances arsenic methylation: results from a folic acid and creatine supplementation randomized controlled trial in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Creatine; Cross-Sectional Studies; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Humans; Inactivation, Metabolic; Male; Mercury Poisoning; Methylation; Middle Aged; Nutrition Therapy; Vitamin B Complex; Water Pollutants, Chemical; Young Adult | 2019 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Topics: Animal Feed; Animals; Autophagy; Chickens; Diet; Dietary Supplements; Folic Acid; Histones; Male; Methylation; Semen Analysis; Sperm Motility; Spermatogenesis; Testis | 2022 |
245 other study(ies) available for isomethyleugenol and folic acid
| Article | Year |
|---|---|
Enzymatic reduction and methylation of folate following pH-dependent, carrier-mediated transport in rat jejunum.
Topics: Animals; Biological Transport, Active; Folic Acid; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Methylation; Oxidation-Reduction; Rats | 1979 |
Alcohol interference with the folate enterohepatic cycle.
Topics: Alcoholism; Animals; Bile; Disease Models, Animal; Enterohepatic Circulation; Female; Folic Acid; Folic Acid Deficiency; Humans; Liver; Methylation; Oxidation-Reduction; Rats | 1977 |
[Role of folic acid in the physiology of the central nervous system].
Topics: Animals; Central Nervous System; Folic Acid; Glutamates; Glycine; Methylation; Purines; Rabbits; Serine | 1978 |
Biosynthesis of ribosylthymine in the transfer RNA of Streptococcus faecalis: a folate-dependent methylation not involving S-adenosylmethionine.
Topics: Enterococcus faecalis; Folic Acid; Formates; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Thymine | 1975 |
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1975 |
Editorial: Metabolic hypotheses in schizophrenia.
Topics: Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Psychotic Disorders; Schizophrenia | 1975 |
Portal and peripheral plasma folates after ingestion of folic acid.
Topics: Adult; Folic Acid; Humans; Liver; Methylation; Middle Aged; Portal Vein | 1976 |
Folate binding protein from kidney brush border membranes contains components characteristic of a glycoinositol phospholipid anchor.
Topics: Animals; Carrier Proteins; Cattle; Cross Reactions; Detergents; Epitopes; Folate Receptors, GPI-Anchored; Folic Acid; Glycolipids; Glycosylphosphatidylinositols; Humans; Hydrolysis; Immune Sera; Kidney; Methylation; Microvilli; Octoxynol; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipases; Phosphoric Diester Hydrolases; Polyethylene Glycols; Rats; Receptors, Cell Surface | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Phenytoin treatment and folate supplementation affect folate concentrations and methylation capacity in rats.
Topics: Animals; Brain; Drug Interactions; Folic Acid; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Phenytoin; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Weight Gain | 1991 |
A relationship between vitamin B12, folic acid, ascorbic acid, and mercury uptake and methylation.
Topics: Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Eating; Folic Acid; Guinea Pigs; Mercury; Methylation; Nutritional Requirements; Organ Specificity; Pilot Projects; Rats; Vitamin B 12 | 1990 |
Methyl group deficiency: effects on one-carbon unit and folate metabolism.
Topics: Animals; Choline Deficiency; Folic Acid; Glycine N-Methyltransferase; Methionine; Methylation; Methyltransferases; Oxidation-Reduction; Rats | 1989 |
Effect of dietary methyl group deficiency on folate metabolism in rats.
Topics: Amino Acids; Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Leucovorin; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; Tetrahydrofolates | 1989 |
Effect of chronic valproate treatment on folate-dependent methyl biosynthesis in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Liver; Male; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Valproic Acid | 1986 |
Effects of nitrous oxide on maternal and embryonic folate metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Body Weight; Chromatography, High Pressure Liquid; Embryo, Mammalian; Female; Fetal Resorption; Folic Acid; Folic Acid Deficiency; Liver; Male; Methylation; Nitrous Oxide; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
Site of reduction and methylation of folic acid in man.
Topics: Administration, Oral; Biological Assay; Biotransformation; Catheterization; Chromatography; Colonic Neoplasms; Enterococcus faecalis; Folic Acid; Hepatic Veins; Humans; Lactobacillus; Liver; Liver Cirrhosis; Methylation; Oxidation-Reduction; Pancreatic Neoplasms; Portal Vein; Tetrazolium Salts; Time Factors | 1971 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
Evidence for reduction and methylation of folate in the intestine during normal absorption.
Topics: Biological Assay; Folic Acid; Glutamates; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Lactobacillus; Methylation; Oxidation-Reduction; Tritium | 1969 |
Intestinal methylation of folates.
Topics: Folic Acid; Humans; Intestinal Absorption; Malabsorption Syndromes; Methylation | 1969 |
Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Media; Folic Acid; Formates; Lacticaseibacillus casei; Ligases; Methionine; Methylation; Pediococcus; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Tetrahydrofolates; Transferases | 1972 |
Escherichia coli B cobalamin methyltransferase: ability of diaphorases and lipoamide dehydrogenases to function as reducing agents.
Topics: Alcohols; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Iodoacetates; Methionine; Methylation; Myocardium; NAD; Spectrophotometry; Sulfhydryl Compounds; Swine; Transferases; Vitamin B 12 | 1970 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
A new hypothesis on the origin of schizophrenia.
Topics: Brain; Folic Acid; Humans; Liposomes; Methylation; Schizophrenia; Tetrahydrofolates | 1974 |
N-5,10-methylenetetrahydrofolate reductase deficiency and schizophrenia: a working hypothesis.
Topics: Adolescent; Dopamine; Female; Fibroblasts; Folic Acid; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Oxidoreductases; Schizophrenia; Tetrahydrofolates | 1974 |
In vitro studies on the effect of hydrazine on the morphogenesis of chick embryos and the mechanism of its action.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Brain; Chick Embryo; Culture Techniques; Folic Acid; Heart; Hydrazines; Methylation; Morphogenesis; Vitamin B 12 | 1974 |
N-methylation of dopamine to epinine in brain tissue using N-methyltetrahydrofolic acid as the methyl donor.
Topics: Animals; Brain; Carbon Isotopes; Coenzymes; Dopamine; Folic Acid; In Vitro Techniques; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1972 |
Methyltetrahydrofolic acid mediates N- and O-methylation of biogenic amines.
Topics: Animals; Biogenic Amines; Brain; Carbon Isotopes; Chickens; Coenzymes; Female; Folic Acid; Hallucinogens; Liver; Lung; Male; Methylamines; Methylation; Methyltransferases; Myocardium; Octopamine; Phenylethanolamine N-Methyltransferase; S-Adenosylmethionine; Serotonin; Tetrahydrofolates; Tryptamines; Tyramine | 1973 |
Irreversible inhibition of thymidylate synthetase by 5-formyl-2'-deoxyuridylic acid.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Chromatography; Drug Stability; Escherichia coli; Folic Acid; Formates; Hydroxyapatites; Kinetics; Lacticaseibacillus casei; Methylation; Methyltransferases; Protein Binding; Schiff Bases; Thymine Nucleotides; Uracil Nucleotides | 1972 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
Absorption of pteroylglutamate and dietary folates in man.
Topics: Administration, Oral; Adult; Animals; Biological Assay; Cattle; Cooking; Dose-Response Relationship, Drug; Enterococcus faecalis; Fasting; Folic Acid; Humans; Intestinal Absorption; Lacticaseibacillus casei; Liver; Meat; Methylation; Nutritional Physiological Phenomena; Oxidation-Reduction; Pediococcus; Species Specificity; Tetrahydrofolates | 1972 |
Radioassay of serum folate, with use of a serum blank and nondialyzed milk as folate binder.
Topics: Animals; Biological Assay; Cattle; Charcoal; Dialysis; Evaluation Studies as Topic; Female; Folic Acid; Hemoglobins; Humans; Lacticaseibacillus casei; Male; Methods; Methylation; Milk; Potassium; Protein Binding; Quality Control; Tetrahydrofolates; Tritium | 1973 |
Composition of pteroylpolyglutamates (conjugated folates) in guinea-pig liver and their formation from folic acid.
Topics: Animals; Biological Assay; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Enterococcus faecalis; Folic Acid; Guinea Pigs; Lacticaseibacillus casei; Liver; Male; Methylation; Oxidation-Reduction; Tritium | 1972 |
Radioassay of serum folate: some criticisms.
Topics: Folic Acid; Humans; Methods; Methylation; Protein Binding; Radioligand Assay | 1973 |
Uptake and reduction of radioactive folate by everted sacs of rat small intestine.
Topics: Animals; Biological Transport; Carbon Isotopes; Chromatography, DEAE-Cellulose; Folic Acid; Intestinal Absorption; Jejunum; Kinetics; Male; Methods; Methotrexate; Methylation; Oxidation-Reduction; Oxygen Consumption; Partial Pressure; Rats; Tetrahydrofolates | 1973 |
Schildt B, Sörbo B,+SORBO B:Studies on the biosynthesis and transfer of labile methyl groups in experimental burns.
Topics: Animals; Burns; Choline; Folic Acid; Liver; Methionine; Methylation; Mice; Vitamin B 12 | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Model studies of thymidylate synthetase. Intramolecular catalysis of 5-hydrogen exchange and 5-hydroxymethylation of 1-substituted uracils.
Topics: Acetals; Carbon Isotopes; Catalysis; Chromatography, Paper; Chromatography, Thin Layer; Deoxyuridine; Deuterium; Ethers, Cyclic; Folic Acid; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Chemical; Protons; Pyrimidinones; Ribonucleosides; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thymidylate Synthase; Tritium; Uracil; Uridine | 1973 |
Multi-step mechanism in the hydrolysis of pteroylpolyglutamates by chicken intestine.
Topics: Animals; Carbon Radioisotopes; Chickens; Chromatography, Gel; Electrophoresis, Paper; Endopeptidases; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Intestines; Iodoacetates; Kinetics; Methylation; Oligopeptides; Spectrophotometry; Structure-Activity Relationship; Time Factors; Tritium | 1974 |
Enzymic synthesis of methionine: formation of a radioactive cobamide enzyme with N5-methyl-14C-tetrahydrofolate.
Topics: Carbon Isotopes; Catalysis; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Kinetics; Methionine; Methylation; Transferases; Vitamin B 12 | 1967 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine methyltransferase: sequential formation of bound methylcobalamin with S-adenosyl-L-methionine and N5-methyltetrahydrofolate.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Light; Methionine; Methylation; Nucleosides; Temperature; Time Factors; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: activation with S-adenosyl-L-methionine and the mechanism for methyl group transfer.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Models, Biological; Nucleosides; Time Factors; Transferases; Vitamin B 12 | 1969 |
The substrate specificity of 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase.
Topics: Escherichia coli; Folic Acid; Glutamates; Homocysteine; Methionine; Methylation; Neurospora; Saccharomyces; Transferases | 1969 |
On the role of S-adenoxylmethionine in the vitamin B12 dependent methionine biosynthesis.
Topics: Alcohols; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxyapatites; Kinetics; Methionine; Methods; Methylation; Nucleosides; Spectrophotometry; Sulfur; Transferases; Vitamin B 12 | 1969 |
Spectrophotometric evidence for the formation of an Escherichia coli B B-12s methyltransferase.
Topics: Alcohols; Carbon Isotopes; Escherichia coli; Folic Acid; Free Radicals; Homocysteine; Hydrogen-Ion Concentration; Iodides; Ligases; Methionine; Methylation; Oxidation-Reduction; Spectrophotometry; Sulfur; Transferases; Ultraviolet Rays; Vitamin B 12 | 1970 |
Properties of thymidylate synthetase from dichloromethotrexate-resistant Lactobacillus casei.
Topics: Drug Resistance, Microbial; Enzyme Activation; Escherichia coli; Folic Acid; Glutamates; Kinetics; Lactobacillus; Mercaptoethanol; Methotrexate; Methylation; Molecular Weight; Pteridines; Spectrophotometry; Transferases; Tritium; Uracil Nucleotides | 1970 |
Inhibition of peptide chain initiation in Escherichia coli by hydroxylamine. Reaction of hydroxylamine with folate coenzymes.
Topics: Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Hydroxylamines; Methionine; Methylation; Oxidoreductases; Oximes; Peptide Biosynthesis; RNA, Transfer; Spectrophotometry; Transferases; Uracil Nucleotides | 1970 |
The vitamin B12-dependent methionine synthetase. The cycle of transmethylation.
Topics: Enzyme Induction; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; Nucleosides; Oxidation-Reduction; Spectrophotometry; Transferases; Vitamin B 12 | 1971 |
Methylcobalamin as a substrate at a separate site on Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase.
Topics: Alkylation; Binding Sites; Carbon Isotopes; Catalysis; Coenzymes; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Temperature; Tritium; Urea; Vitamin B 12 | 1971 |
Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.
Topics: Alkylation; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dithiothreitol; Drug Stability; Escherichia coli; Folic Acid; Homocysteine; Hydroxocobalamin; Macromolecular Substances; Mathematics; Methylation; Methyltransferases; Molecular Weight; Tritium; Urea; Vitamin B 12 | 1971 |
A study of folate absorption and metabolism in man utilizing carbon-14--labeled polyglutamates synthesized by the solid phase method.
Topics: Adult; Aged; Biological Assay; Carbon Isotopes; Chemical Phenomena; Chemistry; Enterococcus faecalis; Feces; Female; Folic Acid; Glutamates; Hodgkin Disease; Humans; Intestinal Absorption; Lactobacillus; Leukemia, Lymphoid; Male; Methods; Methylation; Middle Aged | 1969 |
Metabolism of S-adenosylmethionine in germinating pea seeds: turnover and possible relationships between recycling of sulfur and transmethylation reactions.
Topics: Biological Assay; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Enterococcus faecalis; Folic Acid; Homocystine; Kinetics; Methionine; Methylation; Models, Biological; Nucleosides; Sulfur; Sulfur Isotopes; Tritium | 1969 |
Studies on the absorption and metabolism of folic acid. I. Folate absorption in the dog after exposure of isolated intestinal segments to synthetic pteroylpolyglutamates of various chain lengths.
Topics: Animals; Biological Assay; Carbon Isotopes; Chlorides; Chromatography, DEAE-Cellulose; Copper; Dogs; Enterococcus faecalis; Folic Acid; Glutamates; Intestinal Absorption; Lactobacillus; Ligases; Mesenteric Veins; Methylation; Oxidation-Reduction; Peptides; Tritium | 1971 |
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Carbon Isotopes; Coenzymes; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Methionine; Methylation; Methyltransferases; Oxidoreductases; Vitamin B 12 | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |
A model system for the study of heteroexchange diffusion: methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells.
Topics: Animals; Binding Sites; Biological Transport; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, DEAE-Cellulose; Diffusion; Folic Acid; Folic Acid Antagonists; Formates; Kinetics; Leukemia L1210; Methotrexate; Methylation; Mice; Models, Biological; Tritium | 1971 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
Total synthesis of acetate from CO2. 3. Inhibition by alkylhalides of the synthesis from CO2, methyltetrahydrofolate, and methyl-B12 by Clostridium thermoaceticum.
Topics: Acetates; Alkylation; Butyrates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Chloroform; Clostridium; Coenzymes; Darkness; Depression, Chemical; Enzyme Activation; Fermentation; Folic Acid; Glucose; Hydrocarbons, Halogenated; Iodine; Iron; Keto Acids; Kinetics; Light; Methylation; Photolysis; Pyruvates; Quaternary Ammonium Compounds; Radiation Effects; Sulfates; Time Factors; Vitamin B 12 | 1971 |
Enzymic preparations of radiolabeded (+)-L-5-methyltetrahydrofolate and (+)-L-5-formyltetrahydrofolate.
Topics: Animals; Carbon Isotopes; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Clostridium; Folic Acid; Isotope Labeling; Leucovorin; Leukemia L1210; Methods; Methylation; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Stereoisomerism; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays | 1971 |
Defective metabolism of vitamin B 12 in fibroblasts from children with methylmalonicaciduria.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cobalt Isotopes; Deoxyadenosines; Enzyme Activation; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Malonates; Metabolism, Inborn Errors; Methylation; Methyltransferases; Vitamin B 12 | 1971 |
Methylcobalamin as an intermediate in mammalian methionine biosynthesis.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Electrophoresis; Ethanol; Folic Acid; Homocysteine; Kidney; Methionine; Methylation; Nucleosides; Photochemistry; Solubility; Swine; Transferases; Vitamin B 12 | 1970 |
Methylation of homocysteine in Coprinus lagopus.
Topics: Basidiomycota; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Transferases | 1970 |
Hydrocarbon-utilizing microorganism. Relationship of fatty acid composition and biosynthesis to hydrocarbon substrate and to vitamin B 12 level in Corynebacterium simplex.
Topics: Alkanes; Carbon Isotopes; Cobalt; Corynebacterium; Culture Media; Fatty Acids; Folic Acid; Homocysteine; Methionine; Methylation; Nucleosides; Spectrum Analysis; Transferases; Vitamin B 12 | 1970 |
Biochemical observations in experimental vitamin B12 deficiency.
Topics: Animals; Brain; Coenzyme A; Folic Acid; Liver; Malonates; Methylation; Methyltransferases; Rats; Vitamin B 12 Deficiency | 1970 |
Thymidylate synthetase from amethopterin-resistant Lactobacillus casei.
Topics: Acrylates; Benzoates; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Cyanides; Detergents; Dialysis; Drug Resistance, Microbial; Electrophoresis; Electrophoresis, Disc; Ethylmaleimide; Folic Acid; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyapatites; Iodoacetates; Kinetics; Lactobacillus; Magnesium; Mercury; Methotrexate; Methylation; Molecular Weight; Nucleotides; Quaternary Ammonium Compounds; Sulfates; Sulfhydryl Compounds; Sulfuric Acids; Transferases; Ultracentrifugation; Uracil Nucleotides | 1971 |
[The role of vitamin B12 in metabolism].
Topics: Animals; Coenzymes; Folic Acid; Homocysteine; Humans; Isomerases; Methylation; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Cancerostatic agents. XXXVII. The effect of beta-aroly-beta-halogen acrylic acids on the tetrahydrofolic acid formylase.
Topics: Acrylates; Animals; Antineoplastic Agents; Benzoates; Bromine; Columbidae; Folic Acid; Ligases; Liver; Methylation | 1969 |
The formation of methionine from the monoglutamate form of methyltetrahydrofolate by higher plants.
Topics: Acyltransferases; Carbon Isotopes; Chromatography, Gel; Folic Acid; Glutamates; Kinetics; Methionine; Methylation; Nucleosides; Plants; Vitamin B 12 | 1969 |
Synthesis and properties of 2-amino-4-hydroxy-5,6-dimethyl-5,6,7,8-tetrahydropteridine and the 5,7-dimethyl isomer.
Topics: Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Coenzymes; Folic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methods; Methylation; Pteridines; Spectrum Analysis | 1969 |
The methyl-folate trap and the supply of S-adenosylomethionine.
Topics: Brain; Brain Diseases; Folic Acid; Methionine; Methylation; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1981 |
Melanin: the organizing molecule.
Topics: Animals; Central Nervous System; Chemical Phenomena; Chemistry; Endocrine Glands; Folic Acid; Glycoproteins; Glycosaminoglycans; Homeostasis; Humans; Melanins; Methylation; Neurotransmitter Agents; Polyamines; Pteridines; Purines | 1983 |
Methotrexate hepatotoxicity.
Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides | 1984 |
Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cercopithecus; Disease Models, Animal; Folic Acid; Haplorhini; Macaca fascicularis; Methylation; Methyltransferases; Nerve Tissue; Nitrous Oxide; Peripheral Nervous System Diseases; Spinal Cord Diseases; Vitamin B 12 Deficiency | 1980 |
On the nature of folic-acid-sensitive fragile sites in human chromosomes: an hypothesis.
Topics: Base Composition; Chromatin; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; DNA; Folic Acid; Humans; Methylation; Models, Biological; Nucleoproteins; Thymine; Uracil | 1983 |
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia | 1983 |
Marrow cells from patients with untreated pernicious anaemia cannot use tetrahydrofolate normally.
Topics: Anemia, Megaloblastic; Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Folic Acid; Formyltetrahydrofolates; Humans; Hydroxocobalamin; Methylation; Tetrahydrofolates | 1980 |
Effect of methionine on the metabolic fate of liver folates in vitamin B12-deficient rats.
Topics: Animals; Cells, Cultured; Ethanolamines; Folic Acid; Liver; Male; Methionine; Methylation; Phospholipids; Rats; Stimulation, Chemical; Tetrahydrofolates; Vitamin B 12 Deficiency | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Maternal-fetal folate status and neural tube defects: a case control study.
Topics: Case-Control Studies; Erythrocyte Indices; Erythrocytes; Female; Fetal Blood; Folic Acid; Hematocrit; Hemoglobins; Humans; Male; Maternal-Fetal Exchange; Methylation; Neural Tube Defects; Placenta; Pregnancy | 1995 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1994 |
Effects of prolonged aspirin or acetaminophen administration to rats on liver folate content and distribution. Relation to DNA methylation and S-adenosylmethionine.
Topics: Acetaminophen; Animals; Aspirin; DNA; Drug Administration Schedule; Folic Acid; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intravenous; Male; Methylation; Methylprednisolone Hemisuccinate; Middle Aged; Multiple Sclerosis; Myelin Sheath; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Altered folate-binding protein mRNA stability in KB cells grown in folate-deficient medium.
Topics: Carrier Proteins; Cell Line; Culture Media; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Humans; Methylation; Receptors, Cell Surface; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12 | 1993 |
Folate, methionine, and alcohol intake and risk of colorectal adenoma.
Topics: Adenoma; Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Prevalence; Prospective Studies; Proto-Oncogene Mas; Risk; Surveys and Questionnaires | 1993 |
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats.
Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar | 1995 |
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate.
Topics: Case-Control Studies; Diet; Diet Surveys; Fasting; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methionine; Methylation; Middle Aged; Myocardial Infarction; Odds Ratio; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Liver; Magnetic Resonance Spectroscopy; Methylation; Pneumocystis; Rats; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Toxoplasma | 1996 |
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12 | 1997 |
Homocysteine accumulation in human ovarian carcinoma ascitic/cystic fluids possibly caused by metabolic alteration of the methionine cycle in ovarian carcinoma cells.
Topics: Adult; Aged; Ascitic Fluid; Cysteine; Female; Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Middle Aged; Ovarian Neoplasms; Vitamin B 12 | 1997 |
Folate depletion induced by methotrexate affects methionine synthase activity and its susceptibility to inactivation by nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anesthetics, Inhalation; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methotrexate; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1997 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
Phytosphingosine biosynthesis differs from sphingosine in fish leukocytes and involves a transfer of methyl groups from [3H-methyl]methionine precursor.
Topics: Animals; Bass; Chromatography, Gas; Chromatography, Thin Layer; Folic Acid; Leukocytes; Methylation; Niacinamide; Sphingosine; Tritium | 1998 |
A continuous spectrophotometric assay for thymidine and deoxycytidine kinases.
Topics: Deoxycytidine Kinase; Deoxycytidine Monophosphate; Deoxyuracil Nucleotides; Deoxyuridine; Folic Acid; Herpesvirus 1, Human; Hydrogen-Ion Concentration; Kinetics; Methylation; Spectrophotometry; Tetrahydrofolates; Thymidine Kinase; Thymidylate Synthase | 1998 |
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation.
Topics: Analysis of Variance; Animals; Female; Folic Acid; Gestational Age; Homocysteine; Methionine; Methylation; Rats; Rats, Wistar; Valproic Acid | 1999 |
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Folic Acid; Fruit; Homocysteine; Humans; Logistic Models; Male; Methylation; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Pyridoxine; Risk; Smoking; Vegetables; Vitamin B 12 | 1999 |
The effect of diet on plasma homocysteine concentrations in healthy male subjects.
Topics: Adult; Cross-Sectional Studies; Diet; Diet, Vegetarian; Fasting; Folic Acid; Homocysteine; Humans; Male; Meat; Methionine; Methylation; Middle Aged; Vitamin B 12 | 1999 |
High-dose folic acid supplementation in rats: effects on gestation and the methionine cycle.
Topics: Animals; Dietary Supplements; Female; Fetal Weight; Folic Acid; Methionine; Methylation; Nutritional Status; Pregnancy; Pregnancy Outcome; Rats; Rats, Wistar; S-Adenosylmethionine | 2000 |
Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Age Factors; Animals; Body Weight; Colon; Colorectal Neoplasms; CpG Islands; Cytoskeletal Proteins; Diet; DNA-Binding Proteins; Folic Acid; Intestinal Polyps; Intestine, Small; Methylation; Mice; Mice, Inbred C57BL; Microsatellite Repeats; MutS Homolog 2 Protein; Precancerous Conditions; Proto-Oncogene Proteins | 2000 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.
Topics: Adult; Amino Acids; Cytosol; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Methylation; Mitochondria; Nutritional Status; Pilot Projects; Serine | 2000 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy.
Topics: Adult; Alleles; England; Erythrocytes; Female; Folic Acid; Gene Frequency; Humans; Methionine; Methylation; Mutation; Polyglutamic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Pregnancy; Pteroylpolyglutamic Acids; Spinal Dysraphism; Vitamin B 12 | 2001 |
Relationship between dopamine-stimulated phospholipid methylation and the single-carbon folate pathway.
Topics: Carbon Radioisotopes; Carbon-Nitrogen Ligases; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Humans; Magnetic Resonance Spectroscopy; Methylation; Models, Biological; Phospholipids; Purine Nucleosides; Receptors, Dopamine D2; Receptors, Dopamine D4; Tumor Cells, Cultured | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.
Topics: Cohort Studies; Cross-Sectional Studies; Fasting; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin | 2002 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Topics: Animals; Cell Line; Cytoplasm; Deoxyribonucleotides; DNA; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Methylation; S-Adenosylmethionine; Tetrahydrofolates; Thymidine Monophosphate | 2002 |
Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
Topics: Cohort Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Thymidylate Synthase | 2002 |
Medical hypothesis: hyperhomocysteinemia is a risk factor for estrogen-induced hormonal cancer.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Estradiol; Estrogens; Estrogens, Catechol; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kinetics; Methylation; Models, Biological; Mutagenicity Tests; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Risk Factors; S-Adenosylhomocysteine; Uterine Neoplasms; Vitamin B 12; Vitamin B 6 | 2003 |
Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.
Topics: Cell Transformation, Viral; Cells, Cultured; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Lymphocytes; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin; Tetrahydrofolates | 2003 |
Rôle of folic acid and vitamin B12 in transmethylations. III. An influence of folic acid on the methylation of nicotinamide.
Topics: Folic Acid; Humans; Methylation; Niacin; Niacinamide; Nicotinic Acids; Vitamin B 12; Vitamin B Complex | 1955 |
Enzymatic methylation of homocysteine by a synthetic tetrahydrofolate derivative.
Topics: Cysteine; Folic Acid; Homocysteine; Humans; Methylation; Tetrahydrofolates | 1961 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
STUDIES ON THE ENZYMATIC N- AND O-DEMETHYLATION OF NARCOTIC ANALGESICS AND EVIDENCE FOR THE FORMATION OF CODEINE FROM MORPHINE IN RATS AND DOGS.
Topics: Adenosine Triphosphate; Antitussive Agents; Autoradiography; Carbon Isotopes; Chlorides; Chromatography; Codeine; Dogs; Folic Acid; Glutathione; Liver; Metabolism; Methionine; Methylation; Morphine; NADP; Narcotics; Pharmacology; Rats; Research; Urine | 1964 |
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine | 2004 |
Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Folic Acid; Liver; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Tetrahydrofolates; Tissue Distribution | 2004 |
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Animals; Betaine; Dietary Supplements; Drug Administration Schedule; Fertility; Fertility Agents, Male; Folic Acid; Germ Cells; Infertility, Male; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Sperm Count; Spermatogenesis; Statistics, Nonparametric; Testis | 2005 |
Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis | 2005 |
Folic acid treatment increases homocysteine remethylation and methionine transmethylation in healthy subjects.
Topics: Adult; Amino Acids; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; Vitamins | 2005 |
The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes.
Topics: Computers; DNA; Epidemiologic Studies; Folic Acid; Genotype; Homocysteine; Humans; Italy; Lymphocytes; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2005 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Avitaminosis; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Methylation; Middle Aged; Prevalence | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
MTHFR C677T and A1298C polymorphisms are risk factors for Down's syndrome in Indian mothers.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adolescent; Adult; Alleles; Case-Control Studies; Chi-Square Distribution; Confidence Intervals; Down Syndrome; Female; Folic Acid; Gene Frequency; Homozygote; Humans; India; Male; Maternal Age; Methylation; Middle Aged; Nondisjunction, Genetic; Odds Ratio; Pedigree; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors | 2006 |
Can 5-methyltetrahydrofolate modify the phospholipid fatty acid pattern in cystic fibrosis pediatric patients?
Topics: Adult; Chymotrypsin; Cystic Fibrosis; Dietary Supplements; Docosahexaenoic Acids; Fatty Acids, Omega-6; Female; Folic Acid; Humans; Infant, Newborn; Methylation; Milk, Human; Tetrahydrofolates | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; Female; Folic Acid; Genotype; Head and Neck Neoplasms; Humans; Male; Methylation; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors | 2006 |
Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos.
Topics: Animals; Azacitidine; Embryo Culture Techniques; Embryo, Mammalian; Folic Acid; Methionine; Methylation; Mice; Neural Tube Defects; Phenotype | 2006 |
Iron and the folate-vitamin B12-methylation pathway in multiple sclerosis.
Topics: Adult; Anti-Inflammatory Agents; Black People; Dietary Fats; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Interferons; Iron; Magnetic Resonance Imaging; Male; Methylation; Multiple Sclerosis; Nutritional Status; Patient Compliance; Pilot Projects; Prednisone; Vitamin B 12; White People | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors | 2006 |
Folate and methylation status in relation to phosphorylated tau protein(181P) and beta-amyloid(1-42) in cerebrospinal fluid.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amyloid beta-Peptides; Biomarkers; Cysteine; Female; Folic Acid; Humans; Male; Methylation; Middle Aged; Nervous System Diseases; Neurodegenerative Diseases; Peptide Fragments; Phosphorylation; S-Adenosylhomocysteine; tau Proteins; Vitamin B 12 | 2007 |
Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects.
Topics: Aged; Biomarkers; Caffeine; Cross-Over Studies; Drinking; Eating; Fasting; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Phenols; Polyphenols; Tea; Vitamin B 12 | 2007 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Abnormal folate metabolism in foetuses affected by neural tube defects.
Topics: Anencephaly; Animals; Antimetabolites; Deoxyuridine; Female; Ferredoxin-NADP Reductase; Fetal Diseases; Fetus; Fibroblasts; Folic Acid; Genotype; Humans; Methylation; Mice; Neural Tube Defects; NIH 3T3 Cells; Polymorphism, Genetic; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Dysraphism | 2007 |
[Relationship between 5,10-methylenetetrahydrofolate reductase genetic polymorphism and arsenic metabolism].
Topics: Arsenic; Environmental Exposure; Folic Acid; Gene Frequency; Genotype; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length | 2007 |
Consumption of folate-related nutrients and metabolism of arsenic in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Choline; Cysteine; Dietary Proteins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Niacin; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
Methylation and phosphorylation: a tangled relationship?
Topics: Age Factors; Alzheimer Disease; Biomarkers; Cysteine; Folic Acid; Humans; Methylation; Phosphorylation; S-Adenosylhomocysteine; tau Proteins; Tauopathies | 2007 |
Methylation status in females with rett syndrome.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatine; Female; Folic Acid; Humans; Methionine; Methyl-CpG-Binding Protein 2; Methylation; Rett Syndrome | 2007 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
Plasma folate level, urinary arsenic methylation profiles, and urothelial carcinoma susceptibility.
Topics: Adult; Aged; Aged, 80 and over; Arsenic; Female; Folic Acid; Humans; Male; Methylation; Middle Aged; Surveys and Questionnaires; Urinary Bladder Neoplasms | 2008 |
How does folic acid cure heart attacks?
Topics: Adenosine Triphosphate; Animals; Carbon; Cardiotonic Agents; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Oxidative Stress; Prodrugs; Purines; Rats; Tetrahydrofolates | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.
Topics: Animals; Disease Susceptibility; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylation; Mice; Mice, Transgenic; Mutation; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor | 2008 |
Homocysteine is not associated with global motor or cognitive measures in nondemented older Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Cognition; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Inactivation, Metabolic; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Motor Skills; Neuropsychological Tests; Parkinson Disease; Severity of Illness Index; Vitamin B Complex | 2009 |
Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity.
Topics: Adolescent; Cerebrospinal Fluid; Child; Child, Preschool; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Methotrexate; Methylation; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
Topics: Animals; Animals, Genetically Modified; Biomarkers; DNA; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Homocysteine; Methylation; Mice; Thymidine Monophosphate; Uracil | 2009 |
C1 metabolism and chlorophyll synthesis: the Mg-protoporphyrin IX methyltransferase activity is dependent on the folate status.
Topics: Arabidopsis; Carbon; Chlorophyll; Folic Acid; Light; Methotrexate; Methylation; Methyltransferases; Pisum sativum; Plant Leaves; Tetrahydrofolates | 2009 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity.
Topics: Adolescent; Brain Infarction; Child; Child, Preschool; Demyelinating Diseases; Facial Paralysis; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Methotrexate; Methylation; Neurotoxicity Syndromes; Paresis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Nutrient protection against arsenic toxicity: folate, cysteine support methylation in children.
Topics: Arsenic; Arsenic Poisoning; Child; Cysteine; Dietary Supplements; Folic Acid; Humans; Methylation | 2009 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Chronic pancreatitis is associated with hyperhomocysteinemia and derangements in transsulfuration and transmethylation pathways.
Topics: Adult; Creatinine; Cysteine; Erythrocytes; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Regression Analysis; Signal Transduction; Sulfates; Sulfur; Young Adult | 2010 |
Polymorphisms in one-carbon metabolism pathway genes, urinary arsenic profile, and urothelial carcinoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Arsenic; Cacodylic Acid; Carcinoma, Transitional Cell; Case-Control Studies; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Life Style; Male; Metabolic Networks and Pathways; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Socioeconomic Factors; Taiwan; Urinary Bladder Neoplasms | 2010 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2011 |
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.
Topics: Animals; Carbon; DNA-Binding Proteins; Female; Fibroblasts; Folic Acid; Folic Acid Deficiency; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Mutant Strains; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine Monophosphate; Transcription Factors | 2010 |
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12 | 2011 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Differentiation; Cell Proliferation; Central Nervous System; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Embryo, Mammalian; Epigenomics; Female; Fluorescent Antibody Technique; Folic Acid; Histones; Homeodomain Proteins; Immunoenzyme Techniques; Immunoprecipitation; Jumonji Domain-Containing Histone Demethylases; Luciferases; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Nerve Tissue Proteins; Neural Stem Cells; Neural Tube; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transcription Factor HES-1; Vitamin B Complex | 2010 |
Congenital heart defects and biomarkers of methylation in children: a case-control study.
Topics: Biomarkers; Case-Control Studies; Child, Preschool; Down Syndrome; Female; Folic Acid; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Male; Methylation; Netherlands; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Vitamin B 12 | 2011 |
A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia.
Topics: Adult; Biomarkers; Carbon; Case-Control Studies; Cervix Uteri; Confidence Intervals; Deoxyribonuclease I; DNA Methylation; Epigenomics; Female; Folic Acid; Follow-Up Studies; Humans; Leukocytes, Mononuclear; Logistic Models; Methylation; Middle Aged; Odds Ratio; Papillomavirus Infections; Premenopause; Promoter Regions, Genetic; Prospective Studies; Risk Factors; Surveys and Questionnaires; Uterine Cervical Dysplasia; Vitamin B 12; Vitamin B Complex; Young Adult | 2011 |
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.
Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins | 2011 |
Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1α by PRMT1 and SIRT1.
Topics: Acetylation; Animals; Apoptosis; Cardiomyopathies; Cell Respiration; Energy Metabolism; ERRalpha Estrogen-Related Receptor; Fatty Acids; Female; Folic Acid; Homocysteine; Methylation; Mitochondria, Heart; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Positron-Emission Tomography; PPAR alpha; Protein-Arginine N-Methyltransferases; Proteomics; Rats; Rats, Wistar; Receptors, Estrogen; RNA-Binding Proteins; Sirtuin 1; Stress, Physiological; Transcription Factors; Vitamin B Deficiency | 2011 |
Mathematical model insights into arsenic detoxification.
Topics: Animals; Arsenic; Bangladesh; Dietary Supplements; Folic Acid; Hepatocytes; Humans; Inactivation, Metabolic; Kinetics; Methylation; Models, Biological; Rats | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Interaction between γ-radiation and dietary folate starvation metabolically reprograms global hepatic histone H3 methylation at lysine 4 and lysine 27 residues.
Topics: Animals; Enzyme Induction; Folic Acid; Gamma Rays; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Liver; Lysine; Male; Methylation; Mice | 2012 |
Biochemical and molecular mechanisms of folate transport in rat pancreas; interference with ethanol ingestion.
Topics: Animals; Biological Transport; Cell Membrane; Ethanol; Folic Acid; Folic Acid Transporters; Hydrogen-Ion Concentration; Immunohistochemistry; Male; Membrane Microdomains; Methylation; Micronutrients; Pancreas; Rats; Rats, Wistar; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydrofolates | 2011 |
Folic acid conjugated mPEG-PEI600 as an efficient non-viral vector for targeted nucleic acid delivery.
Topics: Alkanes; Animals; Binding, Competitive; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA; Folic Acid; Green Fluorescent Proteins; Humans; Imines; Light; Magnetic Resonance Spectroscopy; Methylation; Mice; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Particle Size; Polyethylene Glycols; Polyethylenes; Scattering, Radiation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transfection | 2012 |
Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Topics: Binding Sites; Biocatalysis; Corrinoids; Crystallography, X-Ray; Folic Acid; Iron-Sulfur Proteins; Methylation; Methyltransferases; Models, Biological; Models, Molecular; Moorella; Protein Multimerization; Protein Structure, Tertiary; Vitamin B 12 | 2012 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver.
Topics: Animals; Electron Transport; Endoplasmic Reticulum Stress; Energy Metabolism; ERRalpha Estrogen-Related Receptor; Estrogen Receptor alpha; Fatty Acids; Fatty Liver; Folic Acid; Hepatocyte Nuclear Factor 4; Liver; Methylation; Oxidation-Reduction; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; Receptors, Estrogen; RNA-Binding Proteins; Transcription Factors; Vitamin B 12 | 2012 |
Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses.
Topics: Abnormalities, Drug-Induced; Animals; Choline Deficiency; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Folic Acid Transporters; Fumonisins; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Liver; Maternal Nutritional Physiological Phenomena; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Teratogens; Vitamin B 12 Deficiency | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.
Topics: Alkaloids; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA, Complementary; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Immunoblotting; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Molecular Sequence Data; Nicotiana; Nicotine; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 2013 |
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex | 2013 |
Folate polyglutamylation is involved in chromatin silencing by maintaining global DNA methylation and histone H3K9 dimethylation in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Base Sequence; Chromatin; Chromosomes, Plant; DNA Methylation; DNA-Binding Proteins; Folic Acid; Gene Expression Regulation, Plant; Gene Silencing; Genetic Complementation Test; Histones; Immunoblotting; Kanamycin Kinase; Lysine; Methylation; Microscopy, Confocal; Molecular Sequence Data; Mutation; Nuclear Proteins; Peptide Synthases; Plants, Genetically Modified; Polyglutamic Acid; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors | 2013 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Halogenation; Humans; Methylation; Molecular Docking Simulation; Neoplasms; Quinoxalines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Folic acid stimulation of neural stem cell proliferation is associated with altered methylation profile of PI3K/Akt/CREB.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Female; Folic Acid; Gene Regulatory Networks; Methylation; Neural Stem Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Interaction of plasma glutathione redox and folate deficiency on arsenic methylation capacity in Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Glutathione; Glutathione Disulfide; Humans; Male; Methylation; Methyltransferases; Middle Aged; Oxidation-Reduction; S-Adenosylmethionine | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Folate supplementation modifies CCAAT/enhancer-binding protein α methylation to mediate differentiation of preadipocytes in chickens.
Topics: Adipocytes; Animal Feed; Animals; Avian Proteins; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Chickens; Diet; Dietary Supplements; Fatty Acid Synthase, Type I; Female; Folic Acid; Methylation; PPAR gamma; Real-Time Polymerase Chain Reaction | 2014 |
Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.
Topics: Adenocarcinoma; Administration, Oral; Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; Cofilin 1; Dietary Supplements; Endoplasmic Reticulum; Epithelial-Mesenchymal Transition; Folic Acid; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methylation; Mice, SCID; Neoplasm Transplantation; p21-Activated Kinases; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Transport; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction | 2014 |
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12 | 2014 |
Methyl donor deficiency in H9c2 cardiomyoblasts induces ER stress as an important part of the proteome response.
Topics: Animals; Biomarkers; Blotting, Western; Cell Line; Cell Size; Cell Survival; Densitometry; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Stress; Folic Acid; Gene Ontology; Gene Regulatory Networks; Intracellular Space; Methylation; Myocytes, Cardiac; Proteasome Endopeptidase Complex; Proteome; Proteomics; Rats; RNA, Messenger; Time Factors; Ubiquitin; Vitamin B 12 | 2015 |
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.
Topics: Adolescent; Adult; Belgium; Betaine; Choline; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Nutrition Assessment; Reproducibility of Results; Surveys and Questionnaires; Young Adult | 2015 |
Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells.
Topics: Alzheimer Disease; Cell Line, Tumor; Cell Survival; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neuroblastoma; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; tau Proteins | 2015 |
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
Topics: Animals; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Gene Expression Regulation; Heterozygote; Homocystinuria; Lipid Metabolism; Lipogenesis; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Mice, Mutant Strains; Muscle Spasticity; Mutation; Non-alcoholic Fatty Liver Disease; Organ Size; Psychotic Disorders; Specific Pathogen-Free Organisms | 2015 |
[Research of aluminum to the cognitive ability and genome-wide methylation in rats].
Topics: Aluminum; Animals; Body Weight; Cognition; Folic Acid; Learning; Male; Maze Learning; Memory; Methylation; Organometallic Compounds; Pyrones; Rats | 2015 |
Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet.
Topics: Animals; Betaine; Choline; Cysteine; Diet; Feeding Behavior; Folic Acid; Methionine; Methylation; Protein Biosynthesis; Swine | 2016 |
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
Topics: Acetylcholine; Animals; Diet; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Folic Acid; Homocystinuria; Liver; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Muscle Spasticity; Pregnancy; Psychotic Disorders | 2017 |
Epigenetic modifications at DMRs of placental genes are subjected to variations in normal gestation, pathological conditions and folate supplementation.
Topics: Chorionic Villi; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation; Genetic Variation; Genomic Imprinting; Histones; Humans; Methylation; Placenta; Pregnancy; Promoter Regions, Genetic; RNA, Messenger | 2017 |
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
Topics: Animals; Cognition; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Fathers; Folic Acid; Hippocampus; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Learning; Male; Memory; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Neurons; Paternal Inheritance; Promoter Regions, Genetic | 2018 |
Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; DNA (Cytosine-5-)-Methyltransferases; Folic Acid; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Male; Methylation; Mice; Phosphorylation; Protein Phosphatase 2; tau Proteins | 2017 |
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
Topics: Animals; Cilia; Dactinomycin; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic Development; Folic Acid; Gene Expression Regulation, Developmental; Hedgehog Proteins; HEK293 Cells; Humans; Methylation; Mice; Neural Tube; Neural Tube Defects; Plasmids; Septins; Signal Transduction; Xenopus | 2017 |
Influence of phenylketonuria's diet on dimethylated arginines and methylation cycle.
Topics: Arginine; Biomarkers; Child; Chromatography, High Pressure Liquid; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Mass Spectrometry; Methylation; Patient Compliance; Phenylketonurias; Severity of Illness Index; Vitamin B 12 | 2017 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
Mitochondrial translation requires folate-dependent tRNA methylation.
Topics: Aminohydrolases; Biocatalysis; Carrier Proteins; Codon; Electron Transport; Folic Acid; Folic Acid Antagonists; Glycine Hydroxymethyltransferase; GTP-Binding Proteins; Guanosine; HCT116 Cells; HEK293 Cells; Humans; Leucine; Lysine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Oxidative Phosphorylation; Protein Biosynthesis; Ribosomes; RNA-Binding Proteins; RNA, Transfer; Sarcosine; Tetrahydrofolates; Thymine Nucleotides | 2018 |
Understanding pluripotency under folic acid deficiency using embryonic stem cells as an in vitro model.
Topics: DNA; DNA Methylation; Embryonic Development; Embryonic Stem Cells; Epigenesis, Genetic; Female; Folic Acid; Folic Acid Deficiency; Histones; Humans; In Vitro Techniques; Methylation; Micronutrients; Models, Theoretical; Pregnancy; Teratoma | 2018 |
Serum folate levels and urinary arsenic methylation profiles in the US population: NHANES, 2003-2012.
Topics: Adolescent; Adult; Arsenic; Child; Environmental Exposure; Female; Folic Acid; Humans; Linear Models; Male; Methylation; Middle Aged; Nutrition Surveys; United States | 2019 |
A cross-sectional study of general cognitive abilities among Uruguayan school children with low-level arsenic exposure, potential effect modification by methylation capacity and dietary folate.
Topics: Arsenic; Child; Child, Preschool; Cognition; Cross-Sectional Studies; Folic Acid; Humans; Methylation | 2018 |
Quantification of Cellular Folate Species by LC-MS after Stabilization by Derivatization.
Topics: Animals; Bacterial Proteins; Carbon; Chromatography, Liquid; Folic Acid; Folic Acid Antagonists; Hep G2 Cells; Humans; Isotope Labeling; Mammals; Methods; Methylation; Oxidation-Reduction; Pteroylpolyglutamic Acids; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase; Workflow | 2018 |
Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates.
Topics: Animals; Animals, Newborn; Betaine; Blood; Choline; Female; Folic Acid; Male; Methionine; Methylation; Swine; Vitamin U | 2018 |
Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.
Topics: Adult; Arsenic; Biomarkers; Cohort Studies; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylation; Mexico; Pregnancy; Pregnant Women; Regression Analysis; Vitamin B 12; Young Adult | 2018 |
Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase.
Topics: Animals; Carbon-Nitrogen Ligases; Folic Acid; Histidine; Homocysteine; Humans; Methylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases | 2018 |
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission | 2019 |
Two-carbon folate cycle of commensal Lactobacillus reuteri 6475 gives rise to immunomodulatory ethionine, a source for histone ethylation.
Topics: Amino Acids; Carbon; Cell Proliferation; Cells, Cultured; Culture Media; Ethionine; Folic Acid; Histones; Homocysteine; Humans; Immunomodulation; Limosilactobacillus reuteri; Methionine; Methylation; Microbiota; Probiotics; THP-1 Cells; Tumor Necrosis Factor-alpha | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh.
Topics: Adult; Alleles; Ammonia-Lyases; Arsenic; Arsenic Poisoning; Bangladesh; Environmental Exposure; Female; Folic Acid; Gene Frequency; Glutamate Formimidoyltransferase; Humans; Male; Methylation; Methyltransferases; Multifunctional Enzymes; Mutation, Missense; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Skin Diseases; Water Pollutants, Chemical | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
MtpB, a member of the MttB superfamily from the human intestinal acetogen
Topics: Betaine; Demethylation; Energy Metabolism; Eubacterium; Folic Acid; Humans; Intestines; Methylamines; Methylation; Methyltransferases; Microbiota; Proline; Tetrahydrofolates | 2019 |
A diet rich in taurine, cysteine, folate, B
Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; Humans; Hydrogen Sulfide; Methylation; Risk; Taurine; Vitamin B 12 | 2019 |
Association of plasma folate, vitamin B12 levels, and arsenic methylation capacity with developmental delay in preschool children in Taiwan.
Topics: Arsenates; Arsenicals; Arsenites; Cacodylic Acid; Case-Control Studies; Child, Preschool; Developmental Disabilities; Female; Folic Acid; Humans; Male; Methylation; Odds Ratio; Taiwan; Vitamin B 12 | 2019 |
Association between BHMT and CBS gene promoter methylation with the efficacy of folic acid therapy in patients with hyperhomocysteinemia.
Topics: Aged; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Prospective Studies | 2019 |
Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus.
Topics: Animals; Appetite Depressants; Energy Metabolism; Feeding Behavior; Female; Folic Acid; Gene Expression Regulation; Ghrelin; Hypothalamus; Insulin; Lactation; Leptin; Methylation; Peptide YY; Pregnancy; Pro-Opiomelanocortin; Rats; RNA, Messenger; Vitamin B 12 | 2019 |
Tailor-made ternary nanopolyplexes of thiolated trimethylated chitosan with pDNA and folate conjugated cis-aconitic amide-polyethylenimine for efficient gene delivery.
Topics: Chitosan; DNA; Drug Carriers; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Intracellular Space; Methylation; Plasmids; Polyethyleneimine; Sulfhydryl Compounds; Transfection | 2020 |
Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.
Topics: Animals; Folic Acid; Formates; Glycine Dehydrogenase (Decarboxylating); Hydrocephalus; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout | 2020 |
Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Conserved Sequence; Dinitrocresols; Evolution, Molecular; Folic Acid; Methylation; Methyltransferases; Models, Molecular; Nucleic Acids; RNA, Ribosomal, 23S; RNA, Transfer; Tenericutes; Uracil | 2020 |
Association between gene promoter methylation of the one-carbon metabolism pathway and serum folate among patients with hyperhomocysteinemia.
Topics: Carbon; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylation; Promoter Regions, Genetic | 2020 |
Associations of dietary intakes and serum levels of folate and vitamin B-12 with methylation of inorganic arsenic in Uruguayan children: Comparison of findings and implications for future research.
Topics: Arsenic; Arsenicals; Child; Eating; Environmental Exposure; Folic Acid; Humans; Methylation; Research; Uruguay; Vitamin B 12; Vitamins | 2020 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors | 2021 |
Sure, Fathers Give Birth, Too! Postnatal paternal folate deficiency increases congenital disabilities through H3K4me3 histone methylation changes in sperm and embryos.
Topics: Animals; Epigenesis, Genetic; Fathers; Folic Acid; Histones; Humans; Male; Methylation; Mice; Postnatal Care; Spermatozoa | 2021 |
Methionine synthase supports tumour tetrahydrofolate pools.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Methylation; Mutation; Neoplasms; Purines; Tetrahydrofolates; Vitamin B 12 Deficiency | 2021 |
Are UMFA (un-metabolized folic acid) and endocrine disruptor chemicals (EDCs) co-responsible for sperm degradation? An epigenetic/methylation perspective.
Topics: Endocrine Disruptors; Epigenesis, Genetic; Folic Acid; Humans; Male; Methylation; Spermatozoa | 2022 |
Methyl Metabolism and the Clock: An Ancient Story With New Perspectives.
Topics: Animals; Circadian Rhythm; Folic Acid; Humans; Mammals; Methionine; Methylation; S-Adenosylmethionine | 2022 |
Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.
Topics: Animals; Ethanol; Female; Folic Acid; Forkhead Transcription Factors; Inflammation; Liver; Liver Diseases, Alcoholic; Male; Methylation; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory | 2022 |
Effect of Beer Consumption on Methylation and Redox Metabolism.
Topics: Antioxidants; Apolipoproteins; Beer; Betaine; Cholesterol, LDL; Folic Acid; Homocysteine; Humans; Male; Methylation; Oxidation-Reduction; Superoxide Dismutase; Uric Acid; Vitamin B 6 | 2022 |
Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Topics: Adult; Arsenic; Arsenicals; Biomarkers; Birth Weight; Carbon; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2022 |
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions.
Topics: Aldehyde Dehydrogenase 1 Family; Folic Acid; Glycine; Humans; Metabolomics; Methylation; Neoplasms; Retinal Dehydrogenase; S-Adenosylmethionine | 2022 |
Cross-Talk between miRNAs from the Dlk1-Dio3 Locus and Histone Methylation to Protect Male Cerebellum from Methyl Donor Deficiency.
Topics: Animals; Carbon; Cerebellum; DNA Methylation; Female; Folic Acid; Histones; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; MicroRNAs; Rats | 2023 |