Page last updated: 2024-08-18

isomethyleugenol and camptothecin

isomethyleugenol has been researched along with camptothecin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Eng, WK; Hertzberg, RP; Hofmann, GA; Johnson, RK; Mattern, MR; McCabe, FL; Rieman, DJ; Tan, KB; Woessner, RD1
Abbruzzese, JL; Anzai, H; Frost, P1
Desrosiers, R; Tanguay, RM1
Eng, WK; Johnson, RK; Mattern, MR; McCabe, FL; Tan, KB1
Bloom, SE; Muscarella, DE; Vogt, VM1
Dysard, R; Kessel, D1
Che, X; Ji, H; Miao, Z; Shao, L; Sheng, C; Yao, J; You, L; Zhang, J; Zhang, M; Zhang, W1
Beese-Sims, SE; Colaiácovo, MP; Nottke, AC; Pantalena, LF; Reinke, V; Shi, Y1
Ding, Y; Guan, W; Liu, B; Qian, X; Shen, J; Wang, H; Wei, J; Xie, L; Yang, Y; Yu, L; Yue, G; Zou, Z1
Ahlf, DR; Catherman, AD; Durbin, KR; Early, BP; Fellers, RT; Kelleher, NL; Thomas, PM; Tran, JC1
Fan, WF; Liu, BR; Meng, LJ; Shen, J; Wang, J; Wang, L1
Chen, HL; Cheng, PL; Goto, M; Hsieh, KY; Lee, KH; Liu, YQ; Morris-Natschke, SL; Yang, GZ; Yang, QR; Zhang, N; Zhang, XS; Zhu, GX1
Bähr, O; Belka, C; Braun, C; Gerlach, R; Glas, M; Goldbrunner, R; Hänel, M; Hattingen, E; Hau, P; Herrlinger, U; Junold, N; Kebir, S; Kortmann, RD; Krex, D; Mack, F; Niessen, M; Proescholdt, M; Rohde, V; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schmidt-Graf, F; Steinbach, JP; Stuplich, M; Tzaridis, T; Vatter, H; Weyerbrock, A1
Büttner-Herold, M; Distel, L; Fietkau, R; Gottwald, D; Hecht, M; Hohmann, N; Putz, F1

Trials

1 trial(s) available for isomethyleugenol and camptothecin

ArticleYear
Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cell Growth Processes; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiotherapy; Temozolomide; Tumor Suppressor Proteins

2018

Other Studies

13 other study(ies) available for isomethyleugenol and camptothecin

ArticleYear
Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.
    Oncology research, 1992, Volume: 4, Issue:11-12

    Topics: Animals; Camptothecin; Cell Nucleus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Gene Expression; Genes; In Vitro Techniques; Macrophages; Methylation; Mice; RNA, Messenger; Tumor Cells, Cultured

1992
Synergistic cytotoxicity with 2'-deoxy-5-azacytidine and topotecan in vitro and in vivo.
    Cancer research, 1992, Apr-15, Volume: 52, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Colorectal Neoplasms; Decitabine; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lethal Dose 50; Methylation; Mice; Mice, Inbred BALB C; Topotecan; Tumor Cells, Cultured

1992
Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Animals; Camptothecin; Cells, Cultured; Dactinomycin; Drosophila melanogaster; Ethidium; Histones; Hot Temperature; In Vitro Techniques; Methylation; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Uridine

1989
Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.
    Journal of the National Cancer Institute, 1989, Nov-15, Volume: 81, Issue:22

    Topics: Alleles; Amsacrine; Animals; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Gene Expression Regulation; Gene Rearrangement; Leukemia P388; Leukemia, Experimental; Methylation; Methyltransferases; Mice; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic

1989
Characterization of ribosomal RNA synthesis in a gene dosage mutant: the relationship of topoisomerase I and chromatin structure to transcriptional activity.
    The Journal of cell biology, 1987, Volume: 105, Issue:4

    Topics: Aneuploidy; Animals; Camptothecin; Cell Nucleus; Chickens; Chromatin; Dactinomycin; Deoxyribonuclease I; DNA Topoisomerases, Type I; DNA, Ribosomal; Endonucleases; Gene Expression Regulation; Genes; Methylation; RNA Processing, Post-Transcriptional; RNA, Ribosomal; Single-Strand Specific DNA and RNA Endonucleases; Transcription, Genetic

1987
Effects of camptothecin on RNA synthesis in L-1210 cells.
    Biochimica et biophysica acta, 1973, Jul-27, Volume: 312, Issue:4

    Topics: Animals; Camptothecin; Carbon Isotopes; Centrifugation, Density Gradient; Clone Cells; Leukemia L1210; Methylation; Mice; Nucleotides; Phosphorus Isotopes; RNA; RNA, Ribosomal; Time Factors; Uridine

1973
New homocamptothecins: synthesis, antitumor activity, and molecular modeling.
    Bioorganic & medicinal chemistry, 2008, Feb-01, Volume: 16, Issue:3

    Topics: Antineoplastic Agents; Binding Sites; Camptothecin; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type I; Humans; Imaging, Three-Dimensional; Imines; Methylation; Models, Molecular; Molecular Structure; Protein Binding; Pyridines; Quantitative Structure-Activity Relationship; Solubility; Water

2008
SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-02, Volume: 108, Issue:31

    Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Camptothecin; DNA Breaks, Double-Stranded; DNA Repair; Gene Expression Profiling; Germ Cells; Green Fluorescent Proteins; Histones; Lysine; Meiosis; Methylation; Microscopy, Fluorescence; Mutation; Oligonucleotide Array Sequence Analysis; Oxidoreductases, N-Demethylating; Rad51 Recombinase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2011
A three-gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer.
    Journal of translational medicine, 2013, Mar-22, Volume: 11

    Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Camptothecin; Drug Screening Assays, Antitumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Male; Methylation; Mice; Middle Aged; Models, Genetic; Neoplasm Proteins; Reproducibility of Results; Stomach Neoplasms; Sulfatases; Sulfotransferases; Xenograft Model Antitumor Assays

2013
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.
    Molecular & cellular proteomics : MCP, 2013, Volume: 12, Issue:12

    Topics: Camptothecin; Cell Fractionation; Cell Line, Transformed; Cellular Senescence; Chromatography, Liquid; Epithelial Cells; Gene Expression Regulation; High-Throughput Screening Assays; Humans; Membrane Proteins; Methylation; Mitochondria; Mitochondrial Proteins; Molecular Sequence Annotation; Multienzyme Complexes; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Signal Transduction; Tandem Mass Spectrometry

2013
[Correlation between the methylation of SULF2 and WRN promoter and chemosensitivity to irinotecan in gastric cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; DNA Methylation; Exodeoxyribonucleases; Humans; Irinotecan; Methylation; Promoter Regions, Genetic; RecQ Helicases; Stomach Neoplasms; Sulfatases; Sulfotransferases; Werner Syndrome Helicase

2013
Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Humans; Methylation; Neoplasms; Piperazine; Piperazines; Sulfones

2017
Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation.
    BMC molecular and cell biology, 2020, Nov-07, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cadherins; Camptothecin; Cell Line, Tumor; Cell Survival; Cell-in-Cell Formation; Cellular Senescence; Cohort Studies; Female; Fibroblasts; Heat-Shock Response; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Necrosis; Phagocytosis; Prognosis; Rectal Neoplasms

2020