Page last updated: 2024-08-18

isomethyleugenol and betaine

isomethyleugenol has been researched along with betaine in 120 studies

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-199028 (23.33)18.7374
1990's10 (8.33)18.2507
2000's29 (24.17)29.6817
2010's44 (36.67)24.3611
2020's9 (7.50)2.80

Authors

AuthorsStudies
ElAmin, B; Means, GE1
Labadie, P1
Braier, L2
Musich, JA; Rapoport, H1
Storch, KJ; Wagner, DA; Young, VR1
Baker, DH; Czarnecki, GL1
Vance, DE; Yao, ZM1
Pande, SV1
Barak, AJ; Beckenhauer, HC; Tuma, DJ2
Borghesi, E; Gentili, C1
Broquist, HP; Horne, DW1
Nath, MC; Nath, N1
Thompson, W; Wong, ER1
Beart, PM; Johnston, GA1
Howell, JN; Jaenicke, L; Sauer, H1
Beeler, DA; Salerno, DM1
Ishikawa, Y; Melville, DB; Reinhold, VN1
Demain, AL; White, RF1
Morrison, K; Norman, JR; Spitzer, HL1
Pittoni, A; Rubaltelli, FF; Sussi, PL1
Agatov, PA; Galanina, LA1
Barak, AJ; Tuma, DJ1
Pelech, SL; Percival-Smith, A; Pritchard, PH; Sommerman, EF; Vance, DE1
Dunn, WA; Englard, S; Rettura, G; Seifter, E1
Barak, AJ; Kemmy, RJ; Tuma, DJ1
Daveluy, A; Pande, SV; Parvin, R1
Burns, SP; Iles, RA; Leonard, JV; Ryalls, M1
Ganther, HE; Ip, C; Vadhanavikit, S1
Ganther, HE; Goeger, DE1
Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH1
Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J1
Barak, AJ; Beckenhauer, HC; Junnila, M; Rahko, T1
de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C1
Inoue, F; Kinugasa, A; Kizaki, Z; Nakajima, H; Okochi, M; Sawada, T; Terada, N1
Csösz, M; Manninger, K; Tyihák, E1
Kaukinen, P; Kerovuo, J; Nyyssola, A; Reinikainen, T; von Weymarn, N1
Hansen, TA; Jansen, M1
Eilders, LL; Patel, BP; Sims, M; Waddell, TG1
Hanson, AD; McNeil, SD; Nuccio, ML; Ziemak, MJ1
Neuschwander-Tetri, BA1
Bakalli, RI; Chamruspollert, M; Pesti, GM1
Ji, C; Kaplowitz, N1
ERICSON, LE; HARPER, AE1
Kelly, TL; Neaga, OR; Rozen, R; Schwahn, BC; Trasler, JM1
Busby, MG; da Costa, KA; Fischer, L; Mar, MH; Thompson, D; Zeisel, SH1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Aoki, K; Bhuiyan, MN; Hibino, T; Jagendorf, AT; Rai, V; Suzuki, S; Takabe, T; Takano, J; Tanaka, Y; Waditee, R1
Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P1
Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM1
Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Rogers, DD; Siford, GL; Sorrell, MF; Tuma, DJ1
Beers, KW; Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB1
Lawson-Yuen, A; Levy, HL1
Christen, V; Duong, FH; Filipowicz, M; Heim, MH1
Andersen, B; Champlin, SM; Clark, CA; Nordstrom, LJ; Schwinefus, JJ1
Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM1
Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB1
Allen, RH; Brosnan, JT; Brosnan, ME; Jacobs, RL; Mudd, SH; Stabler, SP; Vance, DE; Wagner, C1
Benevenga, NJ1
Os'kina, IN; Plyusnina, IZ; Prasolova, LA; Shchepina, OA; Trut, LN1
Bhuiyan, NH; Hibino, T; Hirata, E; Shikata, M; Takabe, T; Tanaka, Y; Waditee, R1
Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH1
Castro, CC; Garrow, TA; Koutmos, M; Szegedi, SS1
Kharbanda, KK1
Chen, YH; Hsieh, HM; Hu, ML; Lin, HC1
Du, YP; Ling, WH; Peng, JS; Sun, A; Tang, ZH; Zhu, HL1
Cervini-Silva, J; Cornejo-Garrido, H; Del Razo, LM; Fernández-Lomelín, P; Guzmán, J; Hernández-Pineda, J; Rivas-Valdés, MT1
Lever, M; Slow, S1
Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN1
Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q1
Allen, RH; Brenna, JT; Caudill, MA; Gregory, JF; Malysheva, O; Stabler, SP; Wang, W; Yan, J1
Feketeová, L; Khairallah, GN; O'Hair, RA; Yoo, EJ1
Gong, XJ; Guo, M; Jing, LX; Li, D; Lun, YZ; Sun, SX; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS1
Huang, J; Jiang, L; Ren, P; Tang, H; Zhang, L1
Allen, RH; Greiner, LS; Jiang, H; Maclean, KN; Stabler, SP1
Bardag-Gorce, F; Barve, S; Kharbanda, KK; Molina, PE; Osna, NA1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR1
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q1
Bertolo, RF; McBreairty, LE1
Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L1
Baeza, I; Claus, SP; de Castro, NM; de la Fuente, M; Yaqoob, P1
Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D1
Collins, RE; Deming, JW1
Li, QF; Su, SY; Xie, Z; Yu, SL; Zhang, X1
Allen, RH; Brenna, JT; Caudill, MA; Gregory, JF; Jiang, X; Malysheva, OV; Perry, CA; Stabler, SP; West, AA; Yan, J1
Chen, J; Dou, X; Li, S; Qian, Y; Song, Z; Xia, Y; Zhang, X1
Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G2
Cha, HJ; Ha, SC; Jeong, JH; Kim, YG; Rojviriya, C1
Ashapkin, VV; Fedotova, IB; Merzalov, IB; Pavlova, GV; Perepelkina, OV; Poletaeva, II; Surina, NM1
Ferguson, DJ; Girosky, KE; Kountz, DJ; Krzycki, JA; Ticak, T1
Bessaire, T; Delatour, T; Stadler, RH; Tarres, A1
Chen, J; Wang, X; Wang, Y; Zhu, L1
French, SW1
Baumgartner, MR; Blom, HJ; Huemer, M; Kožich, V; Merinero, B; Pasquini, E; Ribes, A; Rinaldo, P1
Chen, J; Wang, X; Wang, Y; Wu, W; Zhou, X2
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Bertolo, RF; Robinson, JL1
Chern, J; Chou, CC; Kuo, CH; Lai, MC; Lai, SJ; Liang, SY; Wu, SH; Wu, WL; Yang, JT1
Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL1
Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; Randell, EW; Robinson, JL1
Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y1
Chan, NL; Lai, MC; Lai, SJ; Lee, YR; Lin, TS; Liu, MS1
Kang, H; Li, Y; Liang, M; Yu, L; Zhang, Z; Zhou, L1
Kageyama, H; Takabe, T; Tanaka, Y1
Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL1
Behrman, EJ; Krzycki, JA; Picking, JW; Zhang, L1
Barker, D; Barrett, J; Barrett, TN; Kerr, WJ; Le, J; Lynn, SM; Macdonald, SJF; Pogany, P; Pratley, C; Pritchard, JM; Procopiou, PA; Roper, JA; Rowedder, JE; Slack, RJ; Taylor, JA; Thompson, JDF; Vitulli, G1
DiNicolantonio, JJ; McCarty, MF; O'Keefe, JH1
Badmann, T; Groll, M1
Asamoah, A; De Biase, I; Gherasim, C; La'ulu, SL; Longo, N; Yuzyuk, T1
Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN1
Elango, R1
Basu, S; Clements, R; Dutta, R; Freeman, EJ; McDonough, J; Singhal, NK; Sternbach, S; Tripathi, A; West, N1
Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E1
Lin, B; Liu, Q; Tao, Y1
Broz, P; Racek, J; Rajdl, D; Stehlík, P; Trefil, L1
Aniagu, S; Chen, J; Chen, T; Ji, C; Jiang, Y; Li, X; Tao, Y; Wang, J1

Reviews

11 review(s) available for isomethyleugenol and betaine

ArticleYear
Betaine, metabolic by-product or vital methylating agent?
    Life sciences, 1983, Feb-14, Volume: 32, Issue:7

    Topics: Alcohol Oxidoreductases; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Diet; Ethanol; Homocysteine; Humans; Liver; Methionine; Methotrexate; Methylation; Methyltransferases; Oxidation-Reduction; Rats; Tetrahydrofolates

1983
Remethylation defects: guidelines for clinical diagnosis and treatment.
    European journal of pediatrics, 1998, Volume: 157 Suppl 2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12

1998
The use of betaine in the treatment of elevated homocysteine.
    Molecular genetics and metabolism, 2006, Volume: 88, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation

2006
Alcoholic liver disease and methionine metabolism.
    Seminars in liver disease, 2009, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine

2009
The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism.
    Clinical biochemistry, 2010, Volume: 43, Issue:9

    Topics: Betaine; Dietary Supplements; Female; Gastrointestinal Agents; Humans; Male; Metabolism; Methylation; Pregnancy

2010
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1

    Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; Methyltransferases; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Tumor Necrosis Factor-alpha

2013
The nutritional burden of methylation reactions.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines

2013
How to prevent alcoholic liver disease.
    Experimental and molecular pathology, 2015, Volume: 98, Issue:2

    Topics: Alcoholism; Animals; Betaine; Energy Metabolism; Epinephrine; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Methylation; Models, Animal; Norepinephrine; Oxidation-Reduction; Phenylethanolamine N-Methyltransferase; Rats

2015
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:6

    Topics: Acetylcarnitine; Betaine; Carnitine; Homocystinuria; Humans; Infant, Newborn; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Neonatal Screening; Practice Guidelines as Topic

2015
The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands.
    Advances in nutrition (Bethesda, Md.), 2016, Volume: 7, Issue:3

    Topics: Amino Acids; Betaine; Diet; DNA Methylation; Folic Acid; Humans; Methionine; Methylation; Neonatology; Nutritional Requirements; Phosphatidylcholines; Protein Biosynthesis

2016
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur

2020

Trials

7 trial(s) available for isomethyleugenol and betaine

ArticleYear
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
    Journal of internal medicine, 1999, Volume: 245, Issue:2

    Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome

1999
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:6

    Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged

2005
Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine.
    Poultry science, 2006, Volume: 85, Issue:1

    Topics: Animals; Betaine; Chickens; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation

2006
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
    Poultry science, 2006, Volume: 85, Issue:10

    Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation

2006
MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline.
    The American journal of clinical nutrition, 2011, Volume: 93, Issue:2

    Topics: Adolescent; Adult; Betaine; Choline; Deuterium; Dietary Supplements; Folic Acid Deficiency; Genotype; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sarcosine; Staining and Labeling; Young Adult

2011
Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:6

    Topics: Adult; Betaine; Choline; Deuterium; Diet; Dietary Supplements; Female; Fetal Blood; Humans; Hydrolysis; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Methylation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Placenta; Pregnancy; Pregnancy Trimester, Third; Young Adult

2013
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
    European journal of nutrition, 2021, Volume: 60, Issue:4

    Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation

2021

Other Studies

102 other study(ies) available for isomethyleugenol and betaine

ArticleYear
Introduction of methyl groups from epsilon-N-methyllysine into the one-carbon pool.
    Biochemical and biophysical research communications, 1979, Jan-30, Volume: 86, Issue:2

    Topics: Animals; Betaine; Carnitine; Chickens; Choline; Liver; Lysine; Methylation; Tissue Distribution

1979
[Methyls of biological importance].
    La Revue du praticien, 1979, Jun-11, Volume: 29, Issue:33

    Topics: Betaine; Carnitine; Choline; Dealkylation; Homocysteine; Humans; Lipid Metabolism; Methane; Methionine; Methylation; Phosphatidylcholines

1979
Anti-benzene compounds. Conversion of benzene to toluene by methyl donors, in man.
    Revista brasileira de pesquisas medicas e biologicas, 1977, Volume: 10, Issue:5

    Topics: Benzene; Betaine; Blood; Choline; Cysteine; Humans; Methylation

1977
Conversion of benezene to toluene by methyl donors in man.
    Nouvelle revue francaise d'hematologie, 1978, Apr-14, Volume: 20, Issue:1

    Topics: Benzene; Betaine; Choline; Cysteine; Methionine; Methylation; Toluene

1978
Reaction of O-methyl-N,N'-diisopropylisourea with amino acids and amines.
    The Journal of organic chemistry, 1977, Jan-07, Volume: 42, Issue:1

    Topics: Amines; Amino Acids; Betaine; Chemical Phenomena; Chemistry; Methylation; Urea

1977
Methionine kinetics in adult men: effects of dietary betaine on L-[2H3-methyl-1-13C]methionine.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:2

    Topics: Adult; Betaine; Carbon Isotopes; Cystine; Deuterium; Diet; Humans; Kinetics; Male; Methionine; Methylation; Nutritional Requirements

1991
Transmethylation of homocysteine to methionine: efficiency in the rat and chick.
    The Journal of nutrition, 1985, Volume: 115, Issue:10

    Topics: Animals; Betaine; Body Weight; Chickens; Choline; Diet; Homocysteine; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Sarcosine; Tetrahydrofolates

1985
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.
    The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19

    Topics: Animals; Apolipoproteins; Betaine; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Deanol; Ethanolamine; Ethanolamines; Homocysteine; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Triglycerides

1989
Synthesis of radioactive (-)-carnitine from gamma-aminobutyrate.
    Methods in enzymology, 1986, Volume: 123

    Topics: Betaine; Carnitine; gamma-Aminobutyric Acid; Methylation

1986
Ethanol, the choline requirement, methylation and liver injury.
    Life sciences, 1985, Sep-02, Volume: 37, Issue:9

    Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates

1985
[Remarks on the level of transmethylases in schizophrenic patients. In vitro assays].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Nov-30, Volume: 43, Issue:22

    Topics: Betaine; Humans; In Vitro Techniques; Methylation; Niacinamide; Schizophrenia

1967
Role of lysine and -N-trimethyllysine in carnitine biosynthesis. I. Studies in Neurospora crassa.
    The Journal of biological chemistry, 1973, Mar-25, Volume: 248, Issue:6

    Topics: Betaine; Butyrates; Carbon Isotopes; Carnitine; Chromatography, Ion Exchange; Culture Media; Hydroxylation; Lysine; Methane; Methionine; Methylation; Models, Chemical; Mutation; Neurospora; Neurospora crassa; Nitrogen Isotopes; Structure-Activity Relationship; Tritium

1973
Effect of ketone bodies and ACTH on the transmethylation reaction (S-adenosyl methionine independent system) in rats. I.
    Enzymologia, 1969, Volume: 36, Issue:2

    Topics: Acetoacetates; Adrenocorticotropic Hormone; Animals; Betaine; Depression, Chemical; Drug Synergism; Homocysteine; Hydroxybutyrates; In Vitro Techniques; Male; Methylation; Rats; Transferases; Vitamin B 12 Deficiency

1969
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver.
    Biochimica et biophysica acta, 1972, Feb-21, Volume: 260, Issue:2

    Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium

1972
GABA uptake in rat brain slices: inhibition by GABA analogues and by various drugs.
    Journal of neurochemistry, 1973, Volume: 20, Issue:2

    Topics: Acetylation; Acylation; Aminobutyrates; Animals; Aspartic Acid; Betaine; Brain; Brain Chemistry; Chlorine; Choline; Esters; Fatty Acids; Fluorine; Glutamates; Glycine; Hydroxylation; Imidazoles; In Vitro Techniques; Methylation; Rats; Sulfur; Tritium; Valerates

1973
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1973, May-21, Volume: 160, Issue:3

    Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12

1973
The biosynthesis of phospholipids and their precursors in rat liver involving de novo methylation, and base-exchange pathways, in vivo.
    Biochimica et biophysica acta, 1973, Dec-20, Volume: 326, Issue:3

    Topics: Animals; Betaine; Choline; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Cytosine Nucleotides; Ethanolamines; Kinetics; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Spectrophotometry, Ultraviolet; Time Factors; Tritium

1973
Conversion of histidine to hercynine by Neurospora crassa.
    Journal of bacteriology, 1970, Volume: 101, Issue:3

    Topics: Betaine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Ergothioneine; Histidine; Methionine; Methylation; Neurospora

1970
Catabolism of betaine and its relationship to cobalamin overproduction.
    Biochimica et biophysica acta, 1971, Apr-20, Volume: 237, Issue:1

    Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12

1971
The incorporation of L-[Me-14C]methionine and [Me-3H]choline into lung phosphatides.
    Biochimica et biophysica acta, 1968, May-01, Volume: 152, Issue:3

    Topics: Animals; Betaine; Carbon Isotopes; Choline; Female; Liver; Lung; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Time Factors; Tritium

1968
Ethionine and methionine biosynthesis in rat liver.
    Experientia, 1969, Jan-15, Volume: 25, Issue:1

    Topics: Animals; Betaine; Ethionine; Homocysteine; Liver; Male; Methionine; Methylation; Rats; Stereoisomerism; Stimulation, Chemical; Transferases

1969
[The effect of conditions instrumental in the process of methylation on the biosynthesis of streptomycin by the Act. streptomycini LS-1 strain].
    Doklady Akademii nauk SSSR, 1966, Jan-01, Volume: 166, Issue:1

    Topics: Betaine; Creatinine; Methionine; Methylation; Streptomyces; Streptomycin; Vitamin B 12; Vitamin B Complex

1966
Methotrexate hepatotoxicity.
    Journal of the American College of Nutrition, 1984, Volume: 3, Issue:1

    Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides

1984
Glucagon inhibits phosphatidylcholine biosynthesis via the CDP-choline and transmethylation pathways in cultured rat hepatocytes.
    Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1984, Volume: 62, Issue:4

    Topics: Animals; Betaine; Cells, Cultured; Choline; Cytidine Diphosphate Choline; Depression, Chemical; Fatty Acids; Female; Glucagon; Insulin; Liver; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains

1984
Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of gamma-butyrobetaine hydroxylase.
    The Journal of biological chemistry, 1984, Sep-10, Volume: 259, Issue:17

    Topics: Animals; Ascorbic Acid Deficiency; Betaine; Carbon Radioisotopes; Carnitine; gamma-Butyrobetaine Dioxygenase; Guinea Pigs; Liver; Lysine; Male; Methylation; Mixed Function Oxygenases; Orosomucoid; Perfusion; Tissue Distribution; Tritium

1984
The effect of methotrexate on homocysteine methylating agents in rat liver.
    Drug-nutrient interactions, 1982, Volume: 1, Issue:4

    Topics: Animals; Betaine; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Inbred Strains; Tetrahydrofolates; Time Factors

1982
Enzymatic synthesis of radioactive (-)-carnitine from gamma-butyrobetaine prepared by the methylation of gamma-aminobutyric acid.
    Analytical biochemistry, 1982, Jan-15, Volume: 119, Issue:2

    Topics: Betaine; Carnitine; Chemical Phenomena; Chemistry; Drug Stability; gamma-Aminobutyric Acid; Isotope Labeling; Methylation; Tritium

1982
Methylgenesis from betaine in cystathionine-beta-synthase deficiency.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine gamma-Lyase; Homocystinuria; Humans; Methylation; Sarcosine

1993
Metabolites of sodium selenite and methylated selenium compounds administered at cancer chemoprevention levels in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Betaine; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylation; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium Compounds; Selenium Radioisotopes; Sodium Selenite; Tissue Distribution

1993
Homocysteine-dependent demethylation of trimethylselenonium ion and selenobetaine with methionine formation.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1

    Topics: Animals; Betaine; Binding, Competitive; Cytosol; Homocysteine; Homocysteine S-Methyltransferase; Kinetics; Liver; Male; Methionine; Methylation; Methyltransferases; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenium Compounds

1993
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
    Journal of cellular biochemistry, 1997, Volume: 64, Issue:2

    Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12

1997
Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:5

    Topics: Administration, Oral; Animals; Betaine; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Coloring Agents; Lipidoses; Lipotropic Agents; Liver; Liver Diseases; Male; Methylation; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tolonium Chloride; Triglycerides

1998
Measurement of carnitine precursors, epsilon-trimethyllysine and gamma-butyrobetaine in human serum by tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Aug-06, Volume: 731, Issue:1

    Topics: Betaine; Carnitine; Humans; Lysine; Mass Spectrometry; Methylation; Reference Standards; Sensitivity and Specificity

1999
Induction of resistance of wheat plants to pathogens by pretreatment with N-methylated substances.
    Acta biologica Hungarica, 1998, Volume: 49, Issue:2-4

    Topics: Betaine; Fungi; Methylation; Triticum; Tyrosine

1998
Extreme halophiles synthesize betaine from glycine by methylation.
    The Journal of biological chemistry, 2000, Jul-21, Volume: 275, Issue:29

    Topics: Amino Acid Sequence; Betaine; Glycine; Halobacteriales; Methylation; Molecular Sequence Data; Sequence Alignment

2000
Non-growth-associated demethylation of dimethylsulfoniopropionate by (homo)acetogenic bacteria.
    Applied and environmental microbiology, 2001, Volume: 67, Issue:1

    Topics: Acetyl Coenzyme A; Betaine; Culture Media; Eubacterium; Genes, rRNA; Gram-Positive Rods; Methylation; Molecular Sequence Data; Phylogeny; Propionates; RNA, Ribosomal, 16S; Sarcosine; Sequence Analysis, DNA; Sulfonium Compounds

2001
Prebiotic methylation and the evolution of methyl transfer reactions in living cells.
    Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2000, Volume: 30, Issue:6

    Topics: Betaine; Biological Evolution; Ethanolamine; Evolution, Chemical; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Methylation; Methyltransferases; Origin of Life; Sulfonium Compounds

2000
Enhanced synthesis of choline and glycine betaine in transgenic tobacco plants that overexpress phosphoethanolamine N-methyltransferase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Aug-14, Volume: 98, Issue:17

    Topics: Betaine; Chloroplasts; Choline; Ethanolamine; Ethanolamines; Genes, Synthetic; Genetic Vectors; Methylation; Methyltransferases; Models, Biological; Mosaic Viruses; Nicotiana; Plant Proteins; Plants, Genetically Modified; Plants, Toxic; Promoter Regions, Genetic; Recombinant Fusion Proteins; Species Specificity; Spinacia oleracea; Transgenes

2001
Betaine: an old therapy for a new scourge.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:9

    Topics: Betaine; Fatty Liver; Hepatitis; Humans; Lipotropic Agents; Methylation

2001
The influence of labile dietary methyl donors on the arginine requirement of young broiler chicks.
    Poultry science, 2002, Volume: 81, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Eating; Female; Male; Methionine; Methylation; Muscle, Skeletal; Nutritional Requirements; Weight Gain

2002
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
    Gastroenterology, 2003, Volume: 124, Issue:5

    Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis

2003
Effect of diet on the betaine-homocysteine transmethylase activity of rat liver. I. Amino acids and protein.
    The Journal of biological chemistry, 1956, Volume: 219, Issue:1

    Topics: Amino Acids; Animals; Betaine; Diet; Enzymes; Homocysteine S-Methyltransferase; Liver; Methylation; Proteins; Rats

1956
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
    Biology of reproduction, 2005, Volume: 72, Issue:3

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Animals; Betaine; Dietary Supplements; Drug Administration Schedule; Fertility; Fertility Agents, Male; Folic Acid; Germ Cells; Infertility, Male; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Sperm Count; Spermatogenesis; Statistics, Nonparametric; Testis

2005
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria.
    Journal of the American Dietetic Association, 2004, Volume: 104, Issue:12

    Topics: Betaine; Choline; Dietary Supplements; Dietetics; Dose-Response Relationship, Drug; Food Analysis; Humans; Metabolism, Inborn Errors; Methylamines; Methylation; Nutrition Policy; Nutritional Requirements; Practice Guidelines as Topic

2004
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
Genes for direct methylation of glycine provide high levels of glycinebetaine and abiotic-stress tolerance in Synechococcus and Arabidopsis.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Feb-01, Volume: 102, Issue:5

    Topics: Arabidopsis; Betaine; Glycine; Methylation; Methyltransferases; Osmolar Concentration; Plants, Genetically Modified; Synechococcus

2005
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12

2005
Role of elevated S-adenosylhomocysteine in rat hepatocyte apoptosis: protection by betaine.
    Biochemical pharmacology, 2005, Dec-05, Volume: 70, Issue:12

    Topics: Adenosine; Animals; Apoptosis; Betaine; Caspase 3; Caspases; Cells, Cultured; Cytoprotection; DNA Fragmentation; Ethanol; Hepatocytes; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine

2005
S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:4

    Topics: Adenosine; Antiviral Agents; Betaine; Cell Line; DNA; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Methylation; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; STAT1 Transcription Factor; Virus Replication

2006
Effect of ethylene glycol, urea, and N-methylated glycines on DNA thermal stability: the role of DNA base pair composition and hydration.
    Biochemistry, 2006, Aug-08, Volume: 45, Issue:31

    Topics: Animals; Base Composition; Base Pairing; Betaine; Cattle; DNA; DNA, Single-Stranded; Ethylene Glycol; Glycine; Methylation; Nucleic Acid Denaturation; Sarcosine; Transition Temperature; Urea

2006
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency

2006
Methyl balance and transmethylation fluxes in humans.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:1

    Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2007
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:4

    Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex

2007
A maternal methyl-containing diet alters learning ability in the Morris swimming test in adult rats.
    Neuroscience and behavioral physiology, 2007, Volume: 37, Issue:5

    Topics: Age Factors; Animal Feed; Animals; Anxiety; Betaine; Brain; Choline; Critical Period, Psychological; Dietary Supplements; Escape Reaction; Female; Gene Expression Regulation, Developmental; Lactation; Male; Maze Learning; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Space Perception; Spatial Behavior

2007
Metabolic engineering for betaine accumulation in microbes and plants.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: Arabidopsis; Bacterial Proteins; Base Sequence; Betaine; Choline; Cyanobacteria; Escherichia coli; Gene Expression; Glycine; Methylation; Molecular Sequence Data; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Phosphorylation; Plants, Genetically Modified; Serine; Water-Electrolyte Balance

2007
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:4

    Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex

2007
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
    The Journal of biological chemistry, 2008, Apr-04, Volume: 283, Issue:14

    Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc

2008
S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Neurotoxicology, 2009, Volume: 30, Issue:4

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Betaine; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Lipotropic Agents; Methylation; Mice; Microglia; Presenilin-1; Promoter Regions, Genetic; S-Adenosylhomocysteine; Time Factors

2009
Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model.
    BMC cancer, 2009, Jul-30, Volume: 9

    Topics: Animals; Betaine; Cyclin-Dependent Kinase Inhibitor p16; Diethylnitrosamine; DNA Methylation; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Liver; Liver Neoplasms; Methylation; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2009
Arsenic(III) methylation in betaine-nontronite clay-water suspensions under environmental conditions.
    Journal of hazardous materials, 2010, Jun-15, Volume: 178, Issue:1-3

    Topics: Aluminum; Aluminum Silicates; Arsenicals; Betaine; Clay; Iron; Methylation; Minerals; Particle Size; Soil; Soil Pollutants; Solutions; Surface Properties; Suspensions; Temperature; Water

2010
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12

2011
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
    The Journal of nutrition, 2010, Volume: 140, Issue:10

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors

2010
Intercluster reactions show that (CH3)2S(+)CH2CO2H is a better methyl cation donor than (CH3)3N(+)CH2CO2H.
    European journal of mass spectrometry (Chichester, England), 2011, Volume: 17, Issue:2

    Topics: Arginine; Betaine; Cations; Methylation; Spectrometry, Mass, Electrospray Ionization; Sulfonium Compounds; Tandem Mass Spectrometry

2011
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2

    Topics: Adult; Betaine; Blood Pressure; Catecholamines; Female; Homocysteine; Humans; Hypertension; Indicators and Reagents; Male; Methylation; Niacinamide; Vitamins

2012
Comprehensive solid-state NMR analysis reveals the effects of N-methylation on the molecular dynamics of glycine.
    The journal of physical chemistry. B, 2012, Jan-12, Volume: 116, Issue:1

    Topics: Betaine; Calorimetry, Differential Scanning; Carbon Isotopes; Glycine; Magnetic Resonance Spectroscopy; Methylation; Molecular Dynamics Simulation; Protons; Sarcosine; Temperature

2012
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
    Molecular genetics and metabolism, 2012, Volume: 105, Issue:3

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha

2012
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult

2012
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen

2013
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:3

    Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex

2013
Premature impairment of methylation pathway and cardiac metabolic dysfunction in fa/fa obese Zucker rats.
    Journal of proteome research, 2013, Apr-05, Volume: 12, Issue:4

    Topics: Adipose Tissue, White; Age Factors; Animals; Betaine; Disease Models, Animal; Inositol; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylation; Myocardium; Obesity; Phosphorylcholine; Rats; Rats, Zucker

2013
Methylation metabolites in amniotic fluid depend on gestational age.
    Prenatal diagnosis, 2013, Volume: 33, Issue:9

    Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2013
An inter-order horizontal gene transfer event enables the catabolism of compatible solutes by Colwellia psychrerythraea 34H.
    Extremophiles : life under extreme conditions, 2013, Volume: 17, Issue:4

    Topics: Adaptation, Physiological; Alteromonadaceae; Bacterial Proteins; Betaine; Choline; Evolution, Molecular; Gene Transfer, Horizontal; Genome, Bacterial; Methylation; Operon; Oxidation-Reduction; Phylogeny; Sarcosine; Sarcosine Oxidase

2013
Duplicated CCAAT/enhancer-binding protein β (C/EBPβ) gene: transcription and methylation changes in response to dietary betaine in Landes goose liver.
    Poultry science, 2013, Volume: 92, Issue:7

    Topics: Amino Acid Sequence; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anseriformes; Base Sequence; Betaine; CCAAT-Enhancer-Binding Protein-beta; Cloning, Molecular; Diet; Liver; Male; Methylation; Molecular Sequence Data; Phylogeny; Transcription, Genetic

2013
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.
    British journal of pharmacology, 2014, Volume: 171, Issue:17

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Betaine; Cells, Cultured; Cytoprotection; Disease Models, Animal; Hep G2 Cells; Humans; Lipolysis; Liver Diseases, Alcoholic; Male; Methylation; Mice; Mice, Inbred C57BL

2014
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
    International journal of food sciences and nutrition, 2014, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult

2014
Structural insights into the histidine trimethylation activity of EgtD from Mycobacterium smegmatis.
    Biochemical and biophysical research communications, 2014, Oct-03, Volume: 452, Issue:4

    Topics: Betaine; Binding Sites; Histidine; Methylation; Models, Chemical; Models, Molecular; Mycobacterium smegmatis; Protein Binding; Protein Conformation; Protein Methyltransferases; Protein Structure, Tertiary

2014
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 127

    Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12

2014
A nonpyrrolysine member of the widely distributed trimethylamine methyltransferase family is a glycine betaine methyltransferase.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Oct-28, Volume: 111, Issue:43

    Topics: Betaine; Chromatography, Thin Layer; Desulfitobacterium; Genes, Bacterial; Glycine N-Methyltransferase; Humans; Lysine; Methylamines; Methylation; Phylogeny; Real-Time Polymerase Chain Reaction

2014
Role of choline and glycine betaine in the formation of N,N-dimethylpiperidinium (mepiquat) under Maillard reaction conditions.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2014, Volume: 31, Issue:12

    Topics: Alkaloids; Betaine; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Deuterium; Hot Temperature; Kinetics; Lysine; Maillard Reaction; Methylation; Models, Chemical; Molecular Structure; Molecular Weight; Piperidines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.
    Public health nutrition, 2015, Volume: 18, Issue:14

    Topics: Adolescent; Adult; Belgium; Betaine; Choline; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Nutrition Assessment; Reproducibility of Results; Surveys and Questionnaires; Young Adult

2015
mRNA m⁶A methylation downregulates adipogenesis in porcine adipocytes.
    Biochemical and biophysical research communications, 2015, Apr-03, Volume: 459, Issue:2

    Topics: Adenosine; Adipocytes; Adipogenesis; Animals; Betaine; Cells, Cultured; Cycloleucine; Down-Regulation; Gene Knockdown Techniques; Lipid Metabolism; Methylation; Methyltransferases; RNA, Messenger; Swine

2015
FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice.
    Journal of physiology and biochemistry, 2015, Volume: 71, Issue:3

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Betaine; Blood Glucose; Cholesterol; Cytoprotection; Diet, High-Fat; Drug Evaluation, Preclinical; Female; Gene Expression; Hepatocytes; Lipid Metabolism; Liver; Methylation; Mice, Inbred C57BL; Mixed Function Oxygenases; Non-alcoholic Fatty Liver Disease; Oxo-Acid-Lyases; RNA Processing, Post-Transcriptional; RNA, Messenger; Weight Gain

2015
The beneficial effects of betaine on dysfunctional adipose tissue and N6-methyladenosine mRNA methylation requires the AMP-activated protein kinase α1 subunit.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:12

    Topics: Adenosine; Adipocytes; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Betaine; Body Weight; Diet, High-Fat; DNA Methylation; Gastrointestinal Agents; Glucose Tolerance Test; Insulin; Lipid Metabolism; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; RNA, Messenger

2015
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
Phosphoproteomic analysis of Methanohalophilus portucalensis FDF1(T) identified the role of protein phosphorylation in methanogenesis and osmoregulation.
    Scientific reports, 2016, 06-30, Volume: 6

    Topics: Amino Acid Sequence; Archaeal Proteins; Betaine; Global Warming; Glycine N-Methyltransferase; Lysine; Methane; Methanosarcinaceae; Methylation; Models, Molecular; Mutation, Missense; Osmoregulation; Phosphoproteins; Phosphorylation; Point Mutation; Protein Conformation; Protein Processing, Post-Translational; Proteomics; Salt Tolerance; Tandem Mass Spectrometry

2016
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
    The Journal of nutritional biochemistry, 2016, Volume: 35

    Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium

2016
Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet.
    Amino acids, 2016, Volume: 48, Issue:12

    Topics: Animals; Betaine; Choline; Cysteine; Diet; Feeding Behavior; Folic Acid; Methionine; Methylation; Protein Biosynthesis; Swine

2016
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:4

    Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult

2017
Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity.
    Scientific reports, 2016, 12-09, Volume: 6

    Topics: Archaeal Proteins; Betaine; Catalytic Domain; Crystallography, X-Ray; Feedback, Physiological; Gene Expression Regulation, Archaeal; Gene Expression Regulation, Enzymologic; Glycine; Glycine N-Methyltransferase; Methanosarcinaceae; Methylation; Models, Molecular; Protein Structure, Secondary; Sarcosine

2016
FTO reduces mitochondria and promotes hepatic fat accumulation through RNA demethylation.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Betaine; Cycloleucine; Demethylation; Epigenesis, Genetic; Fats; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Lipotropic Agents; Methylation; Mitochondria; Protein Conformation; RNA; Swine

2018
Biosynthetic pathways of glycinebetaine in Thalassiosira pseudonana; functional characterization of enzyme catalyzing three-step methylation of glycine.
    Plant physiology and biochemistry : PPB, 2018, Volume: 127

    Topics: Betaine; Choline; Diatoms; Genome; Glycine; High-Throughput Nucleotide Sequencing; Methylation; Methyltransferases

2018
Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates.
    The Journal of nutritional biochemistry, 2018, Volume: 59

    Topics: Animals; Animals, Newborn; Betaine; Blood; Choline; Female; Folic Acid; Male; Methionine; Methylation; Swine; Vitamin U

2018
MtpB, a member of the MttB superfamily from the human intestinal acetogen
    The Journal of biological chemistry, 2019, 09-13, Volume: 294, Issue:37

    Topics: Betaine; Demethylation; Energy Metabolism; Eubacterium; Folic Acid; Humans; Intestines; Methylamines; Methylation; Methyltransferases; Microbiota; Proline; Tetrahydrofolates

2019
Profile of a Highly Selective Quaternized Pyrrolidine Betaine α
    Journal of medicinal chemistry, 2019, 08-22, Volume: 62, Issue:16

    Topics: Animals; Antigens, Neoplasm; Betaine; Cells, Cultured; Crystallography, X-Ray; Hepatocytes; Humans; Integrins; Methylation; Models, Chemical; Molecular Docking Simulation; Molecular Structure; Protein Binding; Protein Conformation; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Stereoisomerism

2019
A diet rich in taurine, cysteine, folate, B
    Medical hypotheses, 2019, Volume: 132

    Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; Humans; Hydrogen Sulfide; Methylation; Risk; Taurine; Vitamin B 12

2019
Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution.
    Chembiochem : a European journal of chemical biology, 2020, 03-16, Volume: 21, Issue:6

    Topics: Bacterial Proteins; Betaine; Biocatalysis; Crystallography, X-Ray; Desulfitobacterium; Methylation; Models, Molecular; Molecular Structure; Tetrahydrofolates

2020
Laboratory evaluation of homocysteine remethylation disorders and classic homocystinuria: Long-term follow-up using a cohort of 123 patients.
    Clinica chimica acta; international journal of clinical chemistry, 2020, Volume: 509

    Topics: Betaine; Cystathionine beta-Synthase; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Laboratories; Methionine; Methylation

2020
The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Brain; Cells, Cultured; Chromatin; DNA (Cytosine-5-)-Methyltransferases; Epigenesis, Genetic; Gene Expression; Histones; Humans; Methionine; Methylation; Multiple Sclerosis; Nitroprusside; Oligodendroglia; Rats; RNA Interference; RNA, Small Interfering; SOXE Transcription Factors

2021
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
    Nutrients, 2021, May-28, Volume: 13, Issue:6

    Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors

2021
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
    Metabolic engineering, 2022, Volume: 72

    Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine

2022
Effect of Beer Consumption on Methylation and Redox Metabolism.
    Physiological research, 2022, Aug-31, Volume: 71, Issue:4

    Topics: Antioxidants; Apolipoproteins; Beer; Betaine; Cholesterol, LDL; Folic Acid; Homocysteine; Humans; Male; Methylation; Oxidation-Reduction; Superoxide Dismutase; Uric Acid; Vitamin B 6

2022
AHR-mediated m
    Journal of hazardous materials, 2023, 09-05, Volume: 457

    Topics: Animals; Betaine; Heart Defects, Congenital; Larva; Methylation; Particulate Matter; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; RNA; Zebrafish

2023