isoline has been researched along with proadifen in 1 studies
| Studies (isoline) | Trials (isoline) | Recent Studies (post-2010) (isoline) | Studies (proadifen) | Trials (proadifen) | Recent Studies (post-2010) (proadifen) |
|---|---|---|---|---|---|
| 10 | 1 | 5 | 1,481 | 0 | 35 |
| Protein | Taxonomy | isoline (IC50) | proadifen (IC50) |
|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.5849 | |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akao, T; Hattori, M; Nakamura, N; Sasahara, M; Takagawa, K; Tang, J; Wang, ZT | 1 |
1 other study(ies) available for isoline and proadifen
| Article | Year |
|---|---|
In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.
Topics: Alanine Transaminase; Animals; Antitussive Agents; Aspartate Aminotransferases; Asteraceae; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Drugs, Chinese Herbal; Esterases; Expectorants; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Monocrotaline; Phenylmethylsulfonyl Fluoride; Proadifen; Pyrrolizidine Alkaloids; Rats; Rats, Sprague-Dawley; Tritolyl Phosphates | 2007 |