isoleucine has been researched along with valine in 2228 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1380 (61.94) | 18.7374 |
| 1990's | 219 (9.83) | 18.2507 |
| 2000's | 304 (13.64) | 29.6817 |
| 2010's | 216 (9.69) | 24.3611 |
| 2020's | 109 (4.89) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Alberti, KG; Blackshear, PJ; Holloway, PA | 1 |
| Asada, Y; Okuzawa, Y; Yamaguchi, K | 1 |
| Muramatsu, N; Nosoh, Y | 1 |
| Haars, L; Hampel, A; Thompson, L | 1 |
| Kasten, R; Kraus, H; Stumpf, B | 1 |
| Bouletreau, P; Delafosse, B; Motin, J | 1 |
| Lebowitz, J; Morrow, G; Revsin, B | 1 |
| Aliotta, G; Fuggi, A; Rigano, C; Rigano, VD; Vona, V | 1 |
| Schlegel, HG; Wiegel, J | 1 |
| Drescher, DG; Lee, KS | 1 |
| Kraus, H; Stumpf, B | 1 |
| Proteau, G; Silver, M | 2 |
| Polglase, WJ; Whitlow, KJ | 1 |
| Ichihara, A | 2 |
| Alekhova, TA; Orlova, TI; Silaev, AB | 2 |
| Gelfand, RA; Hendler, RG; Sherwin, RS | 1 |
| Elia, M; Smith, R; Williamson, DH | 1 |
| Fischer, JE; Freund, HR; Ryan, JA | 1 |
| Alvestrand, A; Bergström, J; Fürst, P | 1 |
| Kilroe-Smith, TA; McLoughlin, JL | 1 |
| Blackshear, PJ | 1 |
| Landaas, S | 1 |
| Garlick, PJ; Millward, DJ; Nnanyelugo, DO; Waterlow, JC | 1 |
| Grizard, J; Maciejewska, M; Pion, R; Prugnaud, J | 1 |
| Chibata, I; Kisumi, M; Komatsubara, S | 6 |
| Leathers, TD; Noti, J; Umbarger, HE | 1 |
| Colten, HR; Strunk, RC; Tashjian, AH | 1 |
| Batshaw, M; Brusilow, S; Walser, M | 1 |
| Fukushima, K; Toyoshima, S | 1 |
| Ingebretsen, WR; Sampson, L; Wagle, SR | 1 |
| Batshaw, ML; Brusilow, S; Walser, M | 1 |
| Hatfield, W; Lawther, RP | 1 |
| Goto, M; Ichihara, A; Shinno, H | 1 |
| Freundlich, M | 2 |
| Porath, U; Schreier, K | 1 |
| Calhoun, DH; Hatfield, GW; Kuska, JS | 1 |
| Hoshino, S; Wakita, M | 1 |
| Ulitzer, S | 1 |
| Kiely, ME; Sourkes, TL | 1 |
| Chibata, I; Kisumi, M; Sugiura, M; Takagi, T | 1 |
| Kiritani, K; Ohnishi, K | 1 |
| Fersht, AR | 2 |
| Freundlich, M; Mastanduno, M; Rizzino, A | 1 |
| Dick, TE; Oxender, DL; Quay, SC | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Anderson, JJ; Oxender, DL | 2 |
| Csonka, LN | 1 |
| Childs, G; Freundlich, M; Sonnenberg, F | 1 |
| Aldanova, NA; Arzamazova, NM; Grinkevich, VA; Moroz, IN; Ovchinnikov, YA | 1 |
| Bakker, AJ; De Boer, HA; Gruber, M | 1 |
| Belaich, A; Belaich, JP; Gaudin, C; Marty, B; Sari, JC | 1 |
| Smith, JM; Umbarger, HE | 1 |
| De Felice, M; Guardiola, J; Iaccarino, M; Lamberti, A; Levinthal, M; Squires, C | 1 |
| Leathers, TD; McCorkle, GM; Umbarger, HE | 1 |
| Kaziro, Y; Miyajima, A | 1 |
| Chang, TW; Goldberg, AL | 1 |
| Hatfield, GW; Lawther, RP; Oxender, DL; Quay, SC | 1 |
| Bridger, WA; Paranchych, W | 1 |
| Bayliss, FT; Brown, CS; Hilderman, RH; Klines, EL; West, R | 1 |
| Blatt, JM; Jackson, JH | 1 |
| Meador, WE; Quiocho, FA | 1 |
| Calhoun, DH; Hahn, JE | 1 |
| De Felice, M; Favre, R; Guardiola, J; Iaccarino, M | 1 |
| Hatfield, GW; Lawther, RP | 1 |
| Duff, JH; Groves, AC; Woolf, LI | 1 |
| Davidson, JP; Williams, LS | 1 |
| Baez, M; Calhoun, DH; Patin, DW | 1 |
| Anraku, Y; Ohki, M; Yamato, I | 1 |
| Aschkenasy, A | 3 |
| Hermodson, MA; Kohlhaw, GB; Lee-Peng, FC | 1 |
| Forlani, G; Marchesini, G; Zoli, M | 1 |
| Fayerman, JT; Umbarger, HE; Vann, MC; Williams, LS | 1 |
| Stevens, CM; Sylvester, SR | 1 |
| Berg, CM; Borucka-Mankiewicz, M; Shaw, KJ; Vender, J | 1 |
| Kline, EL; Manross, DN; Warwick, ML | 1 |
| Fargette, F; Raimond, J | 1 |
| Smith, JM; Umbarger, HE; Wild, J | 1 |
| Gebre-Medhin, M; Larsson, U; Lindblad, BS; Zetterström, R | 1 |
| Amdisen, A; Møller, SE | 1 |
| Molnar, SJ; Rauth, AM | 1 |
| Bresnan, MJ; Levy, HL; Pueschel, SM; Shih, VE | 1 |
| Eisenstein, AB; Gallo-Torres, H; Georgiadis, A; Miller, ON; Strack, I | 1 |
| Müller-Wecker, H; Zimmermann-Telschow, H | 1 |
| Duff, JH; Groves, AC; Moore, JP; Woolf, LI | 1 |
| Castorina-Ziparo, S; Edelstein, E; Fischer, JE; James, JH; Ziparo, V | 1 |
| Lessie, TG; Wong, HC | 1 |
| Berman, M; Bolton, T; Braaten, JT; Foster, D; Hall, SE; McKendry, JB | 1 |
| Buse, MG; Hedden, MP | 1 |
| Colmenares, JL; Wurtman, RJ | 1 |
| Atwell, R; Buse, MG; Mancusi, V | 1 |
| Gupta, VJ; Wilcken, DE | 1 |
| Doi, K; Kuroshima, A; Ohno, T | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Clark, JH; Davis, CL; Derrig, RG; Wohlt, JE | 1 |
| Bensch, KG; Herman, MM; Liao, CL | 1 |
| Milsom, JP; Morgan, MY; Sherlock, S | 2 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 2 |
| Neumann, E; Nolte, HJ | 1 |
| Stevenson, IL | 1 |
| Jones, LA; Smith, FH | 1 |
| Bailey, RS; Fried, B | 1 |
| Gupta, KG; Jain, AK; Yadav, NK | 1 |
| Chaudhary, SK; Prasad, M | 1 |
| Hazue, M; Kato, M | 1 |
| De Montis, MG; Haber, B; Olianas, MC; Tagliamonte, A | 1 |
| Parker, PJ; Randle, PJ | 1 |
| Buse, MG; Frayser, R | 1 |
| Austic, RE; Smith, TK | 1 |
| Cusick, PK; Ferrier, B; Haskell, BE; Koehler, KM | 1 |
| Elsden, SR; Hilton, MG | 1 |
| Roberts, CM; Sokatch, JR | 1 |
| Booth, DA | 1 |
| de Cespedes, C; Estrada, Y; Loria, AR; Nyhan, WL; Sweetman, L | 1 |
| Deak, SB; Laine, RA; Weber, FL | 1 |
| Bell, L; Chao, E; Milne, J | 1 |
| Amanuma, H; Anraku, Y; Awazu, S; Morikawa, A | 1 |
| Caro, L; Cascino, A; Favre, R; Guardiola, J; Iaccarino, M; Kasai, T; Schiavo, FL | 1 |
| Bollon, AP | 3 |
| Oxender, DL; Quay, S | 1 |
| Anderson, JJ; Oxender, DL; Quay, SC | 1 |
| Conrad, RS; Massey, LK; Sokatch, JR | 3 |
| Kwan, SF; Mosteller, RD | 1 |
| Duggan, DE; Hendrickson, ER | 1 |
| Ahmed, SI; Bollon, AP; Magee, PT; Rogers, SJ | 1 |
| Oxender, DL; Quay, SC | 2 |
| Chibata, I; Kato, J; Kisumi, M; Sugiura, M | 1 |
| Amanuma, H; Anraku, Y; Itoh, J | 1 |
| Conrad, RS; Jensen, RA; Sokatch, JR | 1 |
| Cramer, F; von der Haar, F | 2 |
| Brenchley, JE; Jegede, VA; Spencer, F | 1 |
| Horváth, I; Szentirmai, A | 2 |
| Adibi, SA | 4 |
| Smith, JM; Smolin, DE; Umbarger, HE | 1 |
| Chibata, I; Kisumi, M; Sugiura, M | 2 |
| Flossdorf, J; Hinz, HJ; Kula, MR; Weber, K | 1 |
| Murray, CD; Pun, PP; Strauss, N | 1 |
| Aguirre, A; Fischer, JE; Funovics, JM; James, JH; Keane, JM; Wesdorp, RI; Westman, T; Yoshimura, N | 1 |
| Raimond, J | 3 |
| Dale, G; Panter-Brick, M; Wagget, J; Young, G | 1 |
| Ordal, GW | 1 |
| Biswas, GD; Ravin, AW | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Goldstein, BJ; Zahler, SA | 1 |
| Batshaw, M; Brusilow, S; Kulovich, S; Nyhan, W; Spector, E; Thoene, J; Walser, M | 1 |
| Bucovaz, ET; Morrison, JC; Morrison, WC; Sobhy, CM; Trass, TC; Whybrew, WD | 1 |
| Daniel, PM; Pratt, OE; Wilson, PA | 1 |
| Haught, DG; Speer, VC | 1 |
| Brattsten, L; Truex, CR; Visek, WJ | 1 |
| Harper, AE; Shinnick, FL | 1 |
| Wood, FE; Wood, JR | 1 |
| Mitch, W; Walser, M | 1 |
| Cole, DJ; Lewis, D; Taylor, SJ | 1 |
| Aschkenasy, A; Chevalier, P | 1 |
| Grüttner, R; Held, KR; Plettner, C; Singh, S; Sternowsky, HJ | 2 |
| Rappaport, HP | 1 |
| Balloun, SL; Muller, RD | 1 |
| Pattee, PA | 1 |
| Frith, LO; Kirsch, RE; Saunders, SJ | 1 |
| Cummings, MG; Fischer, JE; James, JH; Kean, JM; Soeters, PB | 1 |
| Iinuma, K; Onuma, A; Saito, T; Takamatsu, N; Wada, Y | 1 |
| Molden, DP; Seegmiller, JE; Skaper, SD | 1 |
| Andersen, AE; Avins, L | 1 |
| Neubüser, D; Schäfer, F | 1 |
| Balloun, SL; Tuttle, WL | 1 |
| Chaussain, JL; Georges, P; Job, JC; Olive, G | 2 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Dorizzi, M; Fournier, M; Labouresse, J; Sarger, C | 1 |
| Counahan, R; Cox, BD; El-Bishti, M; Ogg, CS | 1 |
| Korvatskiĭ, BG | 1 |
| Horváth, M; Mestyán, J; Schultz, K; Soltész, G | 1 |
| Jones, C; Moore, EE | 1 |
| Harper, AE; Maruyama, K; Sunde, ML | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Coutts, SM; Hopfield, JJ; Yamane, T; Yue, V | 1 |
| Faller, DV; Fernstrom, JD; Shabshelowitz, H | 1 |
| Ciccimarra, F; Merler, E; Rosen, FS; Schneeberger, E | 1 |
| Brown, CS; Kline, EL; Umbarger, HE | 1 |
| Henderson, EK; Jackson, JH | 1 |
| Burns, RO; Decedue, CJ; Hofler, JG | 1 |
| Bresalier, RS; Freundlich, M; Rizzino, AA | 2 |
| Betz, AL; Drewes, LR; Gilboe, DD | 1 |
| Brown, CS; Coleman, W; Kline, EL; Williams, LS | 1 |
| Gordon, WG; Groves, ML | 1 |
| Bayliss, FT; Kline, EL | 1 |
| Wood, JM | 1 |
| Oxender, DL; Quay, SC; Tsuyumu, S; Umbarger, HE | 1 |
| Tristram, H; Willshaw, GA | 1 |
| Childs, GJ; Freundlich, M | 1 |
| Radler, F; Vollbrecht, D | 2 |
| Savageau, MA | 1 |
| Kline, EL; Oxender, DL; Quay, SC | 1 |
| Corcino, JJ; Klipstein, FA | 1 |
| Deans, PS; Woodham, AA | 1 |
| Fulks, RM; Goldberg, AL; Li, JB | 1 |
| Ensign, JC; Heinzen, RJ | 1 |
| Blomquist, GJ; Lok, JB; Major, MA | 1 |
| Chemke, J; Levin, S | 1 |
| Greco, G; Lorenzi, GP; Mona, R | 1 |
| Fasman, GD; Kubota, S | 1 |
| Baker, DH; Katz, RS | 1 |
| Calhoun, DH | 1 |
| Hajduković, R; Marjanović, B; Stojanović, Lj; Vilhar, N; Vulović, D | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Ivano, E; Kr"steva, A; Lozanova, L; Nedkov-Bratanova, N; Nikolov, N | 1 |
| D'Mello, JP | 2 |
| Fein, JE; MacLeod, RA | 1 |
| Axford, RF; Evans, RA; Offer, NW; Tas, MV | 1 |
| Rüdiger, HW; Wendel, U; Wentrup, H | 1 |
| Perlman, M; Russell, A; Shina, A; Statter, M | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Erfle, JD; Mahadevan, S; Sauer, FD | 1 |
| Kilbey, BJ; Olszewska, E | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Bilmazes, C; Dippel, C; Hambraeus, L; Scrimshaw, N; Young, VR | 1 |
| Doctor, F; Modi, VV | 1 |
| Blomquist, GJ; Kearney, GP | 1 |
| Diksic, M; Grdisa, M; Takada, A | 1 |
| Baudin, V; Bihoreau, MT; Bohn, B; Dumoulin, A; Edelstein, SJ; Kister, J; Lacaze, N; Marden, M; Poyart, C; Schaad, O | 1 |
| Germain, P; Lamsaif, D; Lebrihi, A; Lefebvre, G | 1 |
| Deber, CM; Li, SC | 1 |
| Guerrini, F; Kayser, B; Schena, F; Tregnaghi, P | 1 |
| Ihara, Y; Miyatake, T; Yanagisawa, K | 1 |
| Farran, MT; Thomas, OP | 2 |
| Airas, RK | 1 |
| Bouloc, P; D'Ari, R; Vinella, D | 1 |
| Barefoot, SF; Kline, EL; Nummer, BA | 1 |
| Sneddon, SF; Tobias, DJ | 1 |
| Alemany, M; Fernández-López, JA; Latres, E; Remesar, X | 1 |
| Adams, CW; Hatfield, GW; Pagel, JM; Winkelman, JW | 1 |
| Burnham, D; Emmans, GC; Gous, RM | 1 |
| Calvo, JM; Grandoni, JA; Zahler, SA | 1 |
| Cocco, E; Cossu, G; Manca, L; Masala, B | 1 |
| Calhoun, DH; Coppola, G; Huang, F | 1 |
| Haines, JL; Huang, TL; Hyman, BT; Jenkins, BJ; Mortilla, M; Romano, DM; Tanzi, RE; Tupler, RG; Vaula, G; Wasco, W | 1 |
| Barbour, G; Latshaw, JD | 1 |
| Chetty, N; Metz, J; Reavis, SC; Vieira-Makings, E | 1 |
| Papewalis, J; Rajewsky, MF | 1 |
| Ishiura, S; Maruyama, K; Tagawa, K; Usami, M; Yamao-Harigaya, W | 1 |
| Chang, TM; Gu, KF | 2 |
| Jacobson, DR | 1 |
| Aguilar, OM; Grasso, DH | 1 |
| Goldman, LM; Rapkin, AJ; Reading, AE; Woo, S | 1 |
| Gjermansen, C; Kielland-Brandt, MC; Tullin, S | 1 |
| Hoerr, RA; Marks, L; Pelletier, V; Wagner, DA; Young, VR | 2 |
| Davidson, JP; Wilson, DJ | 1 |
| Bykhovskiĭ, VIa; Fedotcheva, NI; Gessler, NN; Kondrashova, MN | 1 |
| Hoshino, T; Kose-Terai, K; Uratani, Y | 1 |
| Brayer, GD; Charifson, PS; Hamaguchi, N; Pedersen, LG; Smith, KJ; Stafford, DW | 1 |
| Katsuya, T; Miki, T; Ogihara, T; Sakaki, Y; Yoshioka, K | 1 |
| Rogers, QR; Spensley, MS; Willits, NH; Zicker, SC | 1 |
| Hommes, FA; Lee, JS | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Ely, B; Tarleton, JC | 1 |
| Calhoun, DH; Coppola, G; Cox, JL; Hantzopoulos, P; Huang, F; Riley, J; Zhou, LB | 1 |
| Kelly, RA; May, RC; Mitch, WE; Piepenbrock, N | 1 |
| Eisenstein, E | 2 |
| Pallanck, L; Schulman, LH | 1 |
| Rosevear, PR; Williams, JS | 1 |
| Lindblad, BS; Persson, B; Wallensteen, M; Zetterström, R | 1 |
| Baldwin, RL; Padmanabhan, S | 1 |
| LeMaster, DM; Markley, JL; Wang, JF | 1 |
| Carter, RJ; Parsons, HG; Snyder, FF; Unrath, M | 1 |
| Dalle-Feste, C; Hammen, HW; Schadewaldt, P; Wendel, U | 1 |
| Berry, HK; Brunner, RL; Hunt, MM; White, PP | 1 |
| Lawther, RP; Lopes, JM; Ortuno, MJ; White, MC | 1 |
| Alexander-Caudle, C; Jackson, JH; Latinwo, LM | 1 |
| Hatfield, GW; Winkelman, JW | 1 |
| Rank, GH; Xiao, W | 1 |
| Cramer, F; Englisch-Peters, S; von der Haar, F | 1 |
| Ball, JK; Szurek, PF; Wong, PK; Yuen, PH | 1 |
| Gavel, Y; von Heijne, G | 1 |
| Harris, RA; Saitoh, S; Shimomura, Y; Suzuki, M; Suzuki, T; Tasaki, Y | 1 |
| Baldwin, RL; Laue, TM; Marqusee, S; Padmanabhan, S; Ridgeway, T | 1 |
| Broyer, M; Burtin, M; Kleinknecht, C; Laouari, D; Parvy, PR | 1 |
| Jørgensen, KE; Kragh-Hansen, U; Sheikh, MI | 1 |
| Metz, J; van der Westhuyzen, J; Vieira-Makings, E | 1 |
| Hatfield, GW; Wek, RC | 1 |
| Hidaka, K; Iuchi, I; Kimu, K; Morita, T | 1 |
| Lawther, RP; Lopes, JM | 2 |
| Imai, Y; Nakamura, M | 1 |
| Berger, H; Simma, B; Sperl, W | 1 |
| Aoki, H; Fujii, J; Fukui, S; Hayasaka, H; Ikeyama, A; Mizushima, Y; Suzuki, Y; Taki, K | 1 |
| Bartlett, K; Halliday, D; Leonard, JV; Thompson, GN; Walter, JH | 1 |
| Prasad, KU; Urry, DW; Zhang, H | 1 |
| Rasmussen, K | 1 |
| Beck, K; Schadewaldt, P; Wendel, U | 1 |
| Chen, GJ; Russell, JB | 1 |
| Eriksson, T; Eriksson, TE; Voog, L; Wålinder, J | 1 |
| Møller, SE | 2 |
| Ebbighausen, H; Krämer, R; Weil, B | 1 |
| Blusztajn, JK; Caballero, B; Conlay, LA; During, M; Evoniuk, G; Logue, M; Lopez G-Coviella, I; Maher, TJ; Vacanti, CA; Wurtman, RJ | 1 |
| O'Neil, JD; Sykes, BD | 1 |
| Furusawa, M; Hori, S; Kiba, N | 1 |
| Clay, KL; French, TA; Weiner, N | 1 |
| Schäfer, G; Schauder, P; Schröder, MT | 1 |
| Bost, MC; Janssen, MA; Soeters, PB; van Berlo, CL; van de Bogaard, AE; van der Heijden, MA; van Eijk, HM | 1 |
| Carlsson, A; Eriksson, T | 1 |
| Blackmore, JA; Laurence, AS; Parry, TE; Roberts, B | 1 |
| Foster, PA; Fulcher, CA; Houghten, RA; Zimmerman, TS | 1 |
| Mandeli, J; Plaitakis, A; Smith, J; Yahr, MD | 1 |
| Schäfer, G; Schauder, P | 1 |
| Kasperek, GJ | 1 |
| Henriksen, E; Jacob, S; Jaspers, SR; Tischler, ME | 1 |
| Driver, RP; Lawther, RP | 2 |
| Gordeev, VK; Turkov, MI | 1 |
| Binns, MM; Boursnell, ME; Brown, TD; Cavanagh, D; Davis, PJ; Pappin, DJ | 1 |
| Cramer, F; Freist, W | 3 |
| LaRossa, RA; Smulski, DR; Van Dyk, TK | 1 |
| Chen, JW; Harms, E; Higgins, E; Umbarger, HE | 1 |
| Gjermansen, C; Holmberg, S; Kielland-Brandt, MC; Nilsson-Tillgren, T; Petersen, JG; Sigsgaard, P | 1 |
| de Boer, JE; Janssen, MA; Oostenbroek, RJ; Soeters, PB; van Dongen, JJ | 1 |
| Wilson, RP | 1 |
| Lowe, PN; Rowe, AF | 1 |
| Chiku, K; Fukudome, S; Ikemoto, H; Kikuchi, T; Kokuba, Y; Natori, Y; Orita, Y; Tanaka, H; Tsutsui, I | 1 |
| Baker, DH; Funk, MA; Lowry, KR | 1 |
| Besson, F; Hourdou, ML; Michel, G | 1 |
| Hama, H; Shimamoto, T; Tsuchiya, T; Tsuda, M | 1 |
| Herbertz, L; Langer, K; Schauder, P | 1 |
| Holmberg, S; Petersen, JG | 1 |
| Jackson, JH; Williamson, RM | 1 |
| Herbertz, L; Langer, K; Schauder, P; Zavelberg, D | 1 |
| Barak, Z; Chipman, DM; Gollop, N | 1 |
| Kawai, G; Kawakami, M; Kohda, D; Miyazawa, T; Mizushima, S; Yokoyama, S | 1 |
| Ishihara, M; Iwasaki, K; Mano, K; Matsuzawa, T; Yugari, Y | 1 |
| Allen, RH; Lindenbaum, J; Stabler, SP | 1 |
| Chang, DK; Prasad, KU; Urry, DW; Zhang, H | 1 |
| Arndt, K; Fink, GR | 1 |
| Cronan, JE; Dailey, FE | 1 |
| Cassidy, DM; Kealey, T; Laker, MF; Lee, CM | 1 |
| Lenzen, S; Panten, U; Rustenbeck, I; Schmidt, W | 1 |
| Avogaro, A; Cibin, M; Croatto, T; Gallimberti, L; Rizzo, A; Tiengo, A | 1 |
| Cronan, JE; Dailey, FE; Maloy, SR | 1 |
| Lawther, RP; Ortuno, MJ | 1 |
| Hatfield, GW; Lawther, RP; Lopes, JM; Pereira, R; Taillon, BE; Wek, RC | 1 |
| Houstková, H; Hyánek, J; Konecná, L; Pehal, F; Plavka, R; Rubín, A; Verner, P; Wendel, U; Zapadlo, M; Zeman, J | 1 |
| Hertz, L; Murthy, CR | 2 |
| Fernstrom, JD; Fernstrom, MH; Grubb, PE | 1 |
| Formato, M; Gallisai, D; Manca, L; Masala, B; Orzalesi, M | 1 |
| Aftring, RP; Block, KP; Buse, MG | 1 |
| Pastor-Anglada, M; Remesar, X | 1 |
| Goto, N; Musha, H; Okuda, K; Onishi, K; Terabayashi, H | 1 |
| Barrett, J; Grantham, BD | 1 |
| Funayama, CA; Moura-Ribeiro, MV | 1 |
| Katzenellenbogen, JA; Kinder, DH | 1 |
| Betuel, H; Cirillo, D; Esposito, R; Fredel, A; Giordano, C; Lanzetti, N; Manzo, M; Perna, N; Pluvio, M | 1 |
| Calvo, JM; De Felice, M; Haughn, GW; Largo, CT; Squires, CH | 1 |
| Kagamiyama, H; Kuramitsu, S; Ogawa, H; Ogawa, T | 1 |
| Harms, E; Hsu, JH; Subrahmanyam, CS; Umbarger, HE | 1 |
| Harms, E; Hsu, JH; Umbarger, HE | 1 |
| Williams, AL; Williams, LS | 1 |
| Nagashima, H; Ukida, M; Usui, H | 1 |
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66 review(s) available for isoleucine and valine
| Article | Year |
|---|---|
[Variation of plasma amino acids in severe hepatitis with encephalopathy 10 cases].
Topics: Acute Disease; Adult; Aged; Amino Acids; Binding, Competitive; Blood-Brain Barrier; Brain; Brain Diseases; Female; Hepatitis; Humans; Hydroxylation; Isoleucine; Leucine; Male; Middle Aged; Neurotransmitter Agents; Phenylalanine; Tyrosine; Valine | 1977 |
Fluorometric amino-acid analysis with o-phthaldialdehyde (OPA).
Topics: Aldehydes; Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Enzymes; Fluorescamine; Fluorometry; Hydrogen-Ion Concentration; Hydrolysis; Isoleucine; Ninhydrin; o-Phthalaldehyde; Peptides; Proteins; Serine; Threonine; Tryptophan; Valine | 1978 |
[Congenital metabolic acidosis in the postnatal period].
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Fructose-1,6-Diphosphatase Deficiency; Glutarates; Glycogen Storage Disease Type I; Humans; Hyperglycemia; Infant, Newborn; Isoleucine; Ketosis; Lactates; Leucine; Leukoencephalitis, Acute Hemorrhagic; Methylmalonic Acid; Propionates; Syndrome; Thiamine; Valerates; Valine | 1978 |
Regulation and significance of amino acid metabolism in skeletal muscle.
Topics: Alanine; Amino Acids; Animals; Energy Metabolism; Glucose; Glutamine; Isoleucine; Leucine; Muscles; Rats; Valine | 1978 |
Regulation of isoleucine and valine biosynthesis.
Topics: Acetolactate Synthase; Enterobacteriaceae; Enzyme Repression; Genes; Isoleucine; Mutation; Plasmids; RNA, Bacterial; RNA, Messenger; Threonine Dehydratase; Transcription, Genetic; Valine | 1978 |
The role of insulin and glucagon in the plasma aminoacid imbalance of chronic hepatic encephalopathy.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Dogs; Glucagon; Hepatic Encephalopathy; Humans; Insulin; Isoleucine; Leucine; Tryptophan; Tyrosine; Valine | 1979 |
[Physiological chemistry of branched chain amino acids (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Animals; Cell Division; Cell Transformation, Neoplastic; Isoleucine; Leucine; Rats; Transaminases; Valine | 1975 |
Branched-chain amino acid catabolism in bacteria.
Topics: Alcohols; Amino Acid Oxidoreductases; Bacteria; Camphor; Hydro-Lyases; Isoleucine; Ketone Oxidoreductases; Leucine; Mevalonic Acid; Oxidoreductases; Pantothenic Acid; Stereoisomerism; Transaminases; Valine | 1976 |
Relationship of metabolite inhibition of growth to flow-of-carbon patterns in nature.
Topics: 2-Isopropylmalate Synthase; Acetolactate Synthase; Amino Acids; Carbon; Coenzyme A; Fatty Acids; Isoleucine; Keto Acids; Leucine; Models, Biological; Mutation; Nutritional Physiological Phenomena; Pseudomonas; Stereoisomerism; Threonine Dehydratase; Valine | 1976 |
Regulation of branched-chain amino acid biosynthesis.
Topics: 2-Isopropylmalate Synthase; Acetolactate Synthase; Amino Acids; Amino Acyl-tRNA Synthetases; Bacteria; Enzyme Repression; Feedback; Fungi; Isoleucine; Leucine; RNA, Transfer; Threonine Dehydratase; Valine | 1976 |
Metabolism of branched-chain amino acids in altered nutrition.
Topics: Alanine; Amino Acids, Essential; Animals; Biological Transport; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Humans; Isoleucine; Leucine; Liver; Muscles; Protein Deficiency; Rats; Starvation; Transaminases; Valine | 1976 |
Primary sequence of beta, gamma, and caseins.
Topics: Amino Acid Sequence; Animals; Arginine; Caseins; Cattle; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Female; Glutamates; Histidine; Humans; Isoleucine; Lysine; Methionine; Milk Proteins; Molecular Weight; Polymorphism, Genetic; Serine; Temperature; Valine | 1975 |
[Complex regulation of the activity of ilv genes in Escherichia coli K-12 cells].
Topics: Amino Acids; Culture Media; Cyclic AMP; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Guanosine Tetraphosphate; Isoleucine; Mutation; Operon; Protein Biosynthesis; Receptors, Cyclic AMP; Transcription, Genetic; Valine | 1985 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
Quantitative review of optimum amino acid intakes for young laying pullets.
Topics: Amino Acids; Animals; Body Weight; Chickens; Female; Isoleucine; Lysine; Methionine; Nutritional Requirements; Oviposition; Software; Tryptophan; Valine | 1985 |
[Genetics of Staphylococci (author's transl)].
Topics: Galactosidases; Genetics, Microbial; Isoleucine; Lactose; Lysine; Mutation; Operon; Staphylococcus; Transduction, Genetic; Transformation, Genetic; Tryptophan; Valine | 1974 |
[Role of essential amino acids in the treatment of chronic renal failure].
Topics: Age Factors; Amino Acids; Diet Therapy; Diuresis; Glomerular Filtration Rate; Humans; Isoleucine; Kidney Failure, Chronic; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Uremia; Valine | 1972 |
[Metabolic control of branched-chain amino acid biosynthesis--basis reviewed from fermentative field (author's transl)].
Topics: Amino Acids; Enzyme Repression; Feedback; Fermentation; Hydro-Lyases; Isoleucine; Leucine; Serine; Serratia marcescens; Threonine; Valine | 1973 |
Metabolism of alpha-keto analogues of essential amino acids.
Topics: Amination; Amino Acids, Essential; Animals; Female; Glutamates; Glutamine; Isoleucine; Keto Acids; Ketoglutaric Acids; Leucine; Liver; Methionine; Muscles; Perfusion; Phenylalanine; Rats; Sodium; Structure-Activity Relationship; Valine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Biochemical genetics of bacteria.
Topics: Arginine; Chromosomes, Bacterial; Cysteine; Escherichia coli; Genes; Genes, Regulator; Genetic Code; Genetics, Microbial; Histidine; Homeostasis; Isoleucine; Leucine; Methionine; Molecular Biology; Nucleosides; Operon; Purine Nucleotides; Pyrimidines; Salmonella typhimurium; Transcription, Genetic; Tryptophan; Valine | 1974 |
[Initiation of hemoglobin biosynthesis--role of methionine (author's transl)].
Topics: Amino Acids; Aminopeptidases; Animals; Chromatography, Ion Exchange; Erythrocytes; Hemoglobin, Sickle; Hemoglobins; Humans; Isoleucine; Methionine; Peptide Chain Initiation, Translational; Rabbits; Valine | 1974 |
Microbial production of amino acids.
Topics: Amino Acids; Bacteria; Biotin; Chemical Industry; Glutamates; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
Some aspects of amino acid biosynthesis in microorganisms.
Topics: Amino Acids; Aspartic Acid; Bacteria; Enterobacteriaceae; Escherichia coli; Glutamine; Isoleucine; Neurospora; Phenylalanine; Rhodopseudomonas; Tryptophan; Tyrosine; Valine | 1968 |
Absorption of essential amino acids in man.
Topics: Amino Acids; Animals; Biological Transport; Cricetinae; Humans; Intestinal Absorption; Isoleucine; Methionine; Rats; Threonine; Valine | 1968 |
[A case of maple syrup disease. Clinical and electroencephalographic observations with dietetic experiment. Critical review of literature].
Topics: Diet; Electroencephalography; Female; Humans; Infant; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1967 |
Enzymic adaptation in bacteria: its biochemical and genetic basis.
Topics: Acyltransferases; Alkaline Phosphatase; Arabinose; Arginine; Bacteria; Enzyme Induction; Enzyme Repression; Escherichia coli; Galactosidases; Genotype; Histidine; Isoleucine; Kinetics; Leucine; Membrane Transport Proteins; Molecular Biology; Pantothenic Acid; Penicillinase; Phenotype; RNA, Transfer; Tryptophan; Valine | 1968 |
Methymalonic aciduria.
Topics: Child; Chromatography, Gas; Humans; Isoleucine; Isomerases; Liver; Malonates; Metabolism, Inborn Errors; Neurologic Manifestations; Propionates; Valine; Vitamin B 12 Deficiency | 1970 |
The plasma amino acid ratio as an indicator of the protein nutrition status: a review of recent work.
Topics: Amino Acids; Animals; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Chromatography, Paper; Dietary Proteins; Glutamine; Glycine; Humans; Infant; Isoleucine; Kwashiorkor; Leucine; Mathematics; Methionine; Nutrition Disorders; Protein Deficiency; Rats; Serine; Taurine; Valine | 1970 |
[Urinary methylmalonyl acid determination by oral loading of l-valine].
Topics: Administration, Oral; Anemia; Diabetes Mellitus; Humans; Isoleucine; Liver Diseases; Malonates; Nervous System Diseases; Valine; Vitamin B 12 Deficiency | 1970 |
A conspectus of research on amino acid requirements of man.
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acids; Arginine; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Histidine; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Isoleucine; Leucine; Lysine; Methionine; Middle Aged; Nutritional Requirements; Phenylalanine; Threonine; Tryptophan; Valine | 1971 |
Some questions about the structure and activity of aminoacyl-tRNA synthetases.
Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Cations, Divalent; Inosine; Isoleucine; Isomerism; Kinetics; Methionine; Methylation; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Protein Binding; Pseudouridine; Ribonucleotides; RNA, Transfer; Species Specificity; Sulfhydryl Compounds; Sulfur; Tyrosine; Uracil; Valine | 1971 |
Genetics of Pseudomonas.
Topics: Amidohydrolases; Bacteriocins; Bacteriophages; Chromosomes, Bacterial; Drug Resistance, Microbial; Genetics, Microbial; Isoleucine; Lysogeny; Mutation; Phenotype; Pseudomonas; Pseudomonas aeruginosa; Pyrimidines; Radiation Effects; Recombination, Genetic; Sex Factors; Temperature; Transduction, Genetic; Transformation, Genetic; Tryptophan; Valine | 1969 |
Metabolite analogs as genetic and biochemical probes.
Topics: Amino Acids; Bacillus subtilis; Drug Resistance, Microbial; Escherichia coli; Genes; Genes, Regulator; Genetics, Microbial; Histidine; Isoleucine; Leucine; Models, Biological; Molecular Biology; Mutation; Operon; Phenylalanine; Salmonella typhimurium; Tryptophan; Tyrosine; Valine | 1971 |
Roles of branched-chain amino acids in metabolic regulation.
Topics: Absorption; Amino Acids, Branched-Chain; Gluconeogenesis; Glycine; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Isoleucine; Leucine; Lipids; Muscle Proteins; Muscles; Neurotransmitter Agents; Valine | 1980 |
[Branched amino acids. Role and value in parenteral nutrition].
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus; Hormones; Humans; Infant; Infant, Newborn; Intestinal Absorption; Isoleucine; Leucine; Liver Diseases; Muscles; Nutrition Disorders; Parenteral Nutrition; Valine | 1980 |
Branched-chain amino acid metabolism.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Chemical Phenomena; Chemistry, Physical; Cytosol; Dietary Proteins; Enzyme Activation; Hemiterpenes; Hormones; Humans; Isoenzymes; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Liver; Mitochondria; Multienzyme Complexes; Nitrogen; Oxidation-Reduction; Substrate Specificity; Tissue Distribution; Transaminases; Valine | 1984 |
Amino acid degradation by anaerobic bacteria.
Topics: Amino Acids; Anaerobiosis; Aspartic Acid; Clostridium; Culture Media; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1981 |
[Regulatory mechanism of ilv operon and role of isoleucine (author's transl)].
Topics: Acetolactate Synthase; Base Sequence; Cell Division; Escherichia coli; Gene Expression Regulation; Isoleucine; Operon; Valine | 1982 |
Fuel selection at the level of mitochondria in mammalian tissues.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Calcium; Citrates; Energy Metabolism; Humans; Isoleucine; Leucine; Mitochondria; Oxidation-Reduction; Pyruvates; Rats; Valine | 1995 |
Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility.
Topics: Chromosome Aberrations; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Humans; Isoenzymes; Isoleucine; Lung Neoplasms; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Smoking; Valine | 1995 |
Alzheimer's disease families with amyloid precursor protein mutations.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Brain; Glycine; Humans; Isoleucine; Point Mutation; Valine | 1993 |
Methylmalonic acidemia, cobalamin C type, presenting with cutaneous manifestations.
Topics: Acrodermatitis; Amino Acid Metabolism, Inborn Errors; Biopsy; Cheilitis; Female; Humans; Infant, Newborn; Isoleucine; Methylmalonic Acid; Skin; Skin Diseases, Metabolic; Valine; Vitamin B 12 Deficiency | 1997 |
[2-Methylbranched chain acyl-CoA-dehydrogenase deficiency].
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Humans; Isoleucine; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prognosis; Valine | 1998 |
[MAPLE SYRUP URINE DISEASE].
Topics: Blood Chemical Analysis; Body Fluids; Chemical Phenomena; Chemistry; Diet; Diet Therapy; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Urine; Valine | 1963 |
[AMINO ACID TOXICITY AND CONGENITAL AMINO ACID METABOLIC DISORDERS].
Topics: Amino Acids; Aspartic Acid; Glutamates; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proteins; Toxicology; Tryptophan; Valine | 1964 |
Branched-chain amino acid requirements in healthy adult human subjects.
Topics: Adult; Amino Acids, Branched-Chain; Humans; Isoleucine; Leucine; Nutritional Requirements; Oxidation-Reduction; Valine | 2006 |
Amino acid metabolism in patients with propionic acidaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Citric Acid Cycle; Diet; Glutamine; Glycine; Humans; Isoleucine; Lysine; Methylmalonyl-CoA Decarboxylase; Models, Biological; Propionic Acidemia; Urea; Valine | 2012 |
CYP1A1 Ile462Val polymorphism contributes to colorectal cancer risk: a meta-analysis.
Topics: Case-Control Studies; Colorectal Neoplasms; Cytochrome P-450 CYP1A1; Female; Genotype; Humans; Isoleucine; Male; Models, Genetic; Odds Ratio; Polymorphism, Genetic; Risk; Risk Factors; Valine | 2011 |
CYP1A1 Ile462Val polymorphism and susceptibility to lung cancer: a meta-analysis based on 32 studies.
Topics: Asian People; Case-Control Studies; Cytochrome P-450 CYP1A1; Genetic Markers; Genetic Predisposition to Disease; Humans; Isoleucine; Lung Neoplasms; Polymorphism, Genetic; Valine | 2011 |
New therapeutic strategy for amino acid medicine: notable functions of branched chain amino acids as biological regulators.
Topics: Animals; Gluconeogenesis; Glucose; Humans; Isoleucine; Leucine; Liver; Muscle Proteins; Oxidation-Reduction; Rats; Valine | 2012 |
CYP1A1 Ile462Val polymorphism contributes to lung cancer susceptibility among lung squamous carcinoma and smokers: a meta-analysis.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Cytochrome P-450 CYP1A1; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Lung Neoplasms; Models, Genetic; Odds Ratio; Polymorphism, Genetic; Smoking; Valine | 2012 |
Polymorphisms of ERBB2 and breast cancer risk: a meta-analysis of 26 studies involving 35,088 subjects.
Topics: Adult; Aged; Alanine; Alleles; Asian People; Black People; Breast Neoplasms; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Proline; Receptor, ErbB-2; Risk Factors; Valine; White People | 2013 |
The effects of ABCC2 G1249A polymorphism on the risk of resistance to antiepileptic drugs: a meta-analysis of the literature.
Topics: Amino Acid Substitution; Anticonvulsants; Drug Resistance; Epilepsy; Humans; Isoleucine; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Risk Factors; Valine | 2014 |
Glutathione S-transferase gene polymorphisms and susceptibility to acute myeloid leukemia: meta-analyses.
Topics: Asian People; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Leukemia, Myeloid, Acute; Odds Ratio; Polymorphism, Genetic; Risk Factors; Valine; White People | 2014 |
Tardive dyskinesia (syndrome): Current concept and modern approaches to its management.
Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; alpha-Tocopherol; Amantadine; Anticonvulsants; Antioxidants; Antipsychotic Agents; Clonazepam; Dopamine Agents; Drugs, Chinese Herbal; Fatty Acids, Omega-3; Ginkgo biloba; Humans; Isoleucine; Isoxazoles; Leucine; Levetiracetam; Melatonin; Movement Disorders; Nootropic Agents; Piracetam; Plant Extracts; Propranolol; Pyridoxine; Resveratrol; Stilbenes; Tetrabenazine; Valine; Vitamins; Zonisamide | 2015 |
Effects of medical food leucine content in the management of methylmalonic and propionic acidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Deficiency Diseases; Diet, Protein-Restricted; Foods, Specialized; Homocystinuria; Humans; Isoleucine; Leucine; Propionic Acidemia; Valine; Vitamin B 12 Deficiency | 2018 |
Branched Chain Amino Acids: Beyond Nutrition Metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Isoleucine; Leucine; Metabolic Diseases; Signal Transduction; Valine | 2018 |
Bariatric surgery reduces branched-chain amino acids' levels: a systematic review and meta-analysis.
Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Female; Humans; Isoleucine; Leucine; Male; Valine; Weight Loss | 2021 |
The role of skeletal muscle in the pathogenesis of altered concentrations of branched-chain amino acids (valine, leucine, and isoleucine) in liver cirrhosis, diabetes, and other diseases.
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus; Humans; Isoleucine; Leucine; Liver Cirrhosis; Metabolic Diseases; Muscle, Skeletal; Valine | 2021 |
Association of circulating branched-chain amino acids with risk of cardiovascular disease: A systematic review and meta-analysis.
Topics: Adult; Amino Acids, Branched-Chain; Cardiovascular Diseases; Humans; Isoleucine; Leucine; Middle Aged; Prospective Studies; Risk Factors; Valine | 2022 |
Branched-chain amino acids as a novel biomarker of metabolic disturbances in women with polycystic ovary syndrome - literature review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Obesity; Polycystic Ovary Syndrome; Prediabetic State; Valine | 2022 |
The Association between Circulating Branched Chain Amino Acids and the Temporal Risk of Developing Type 2 Diabetes Mellitus: A Systematic Review & Meta-Analysis.
Topics: Amino Acids, Branched-Chain; Biomarkers; Diabetes Mellitus, Type 2; Humans; Isoleucine; Leucine; Valine | 2022 |
Emerging role for branched-chain amino acids metabolism in fibrosis.
Topics: Amino Acids, Branched-Chain; Fibrosis; Humans; Isoleucine; Leucine; Valine | 2023 |
Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites.
Topics: Adult; Alanine; Birth Weight; Child; Genome-Wide Association Study; Humans; Insulin Resistance; Isoleucine; Leucine; Non-alcoholic Fatty Liver Disease; Pediatric Obesity; Polymorphism, Single Nucleotide; Valine | 2023 |
Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acids; Amino Acids, Branched-Chain; Case-Control Studies; Humans; Isoleucine; Leucine; Middle Aged; Valine; Young Adult | 2023 |
36 trial(s) available for isoleucine and valine
| Article | Year |
|---|---|
Branched-chain amino acid supplementation during trekking at high altitude. The effects on loss of body mass, body composition, and muscle power.
Topics: Adult; Altitude; Amino Acids, Branched-Chain; Body Composition; Energy Intake; Female; Humans; Isoleucine; Leucine; Male; Muscles; Placebos; Valine; Walking | 1992 |
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes.
Topics: Adult; Carbon Isotopes; Deuterium; Fasting; Food; Humans; Infusions, Intravenous; Isoleucine; Kinetics; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Valine | 1991 |
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes.
Topics: Adult; Carbon Isotopes; Humans; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Valine | 1991 |
Valine, isoleucine, and leucine. A new treatment for phenylketonuria.
Topics: Adolescent; Adult; Attention; Child; Double-Blind Method; Humans; Isoleucine; Language Tests; Leucine; Memory; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Randomized Controlled Trials as Topic; Valine | 1990 |
Pilot trial of branched-chain aminoacids in amyotrophic lateral sclerosis.
Topics: Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Drug Combinations; Female; Humans; Isoleucine; Leucine; Locomotion; Male; Middle Aged; Muscles; Neurologic Examination; Patient Compliance; Spinal Cord; Valine | 1988 |
Comparison of total parenteral nutrition with 25 per cent and 45 per cent branched chain amino acids in stressed patients.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Isoleucine; Leucine; Male; Methylhistidines; Middle Aged; Muscles; Nitrogen; Parenteral Nutrition, Total; Prospective Studies; Random Allocation; Stress, Physiological; Valine | 1985 |
Intravenous nutrition with amino acid solutions in patients with chronic uraemia.
Topics: Adult; Aged; Amino Acids; Arginine; Diet Therapy; Female; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Phenylalanine; Threonine; Tryptophan; Urea; Uremia; Valine | 1972 |
A comparison of the effects of intravenous infusion of individual branched-chain amino acids on blood amino acid levels in man.
Topics: Adult; Amino Acids; Blood Glucose; Female; Humans; Infusions, Parenteral; Insulin; Isoleucine; Leucine; Male; Valine | 1981 |
A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data.
Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Analysis of Variance; Double-Blind Method; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Threonine; Valine | 1996 |
Glutamine and other amino acid losses during continuous venovenous hemodiafiltration.
Topics: Acute Kidney Injury; Adult; Aged; Amino Acids; Female; Glutamine; Hemodiafiltration; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Multiple Organ Failure; Parenteral Nutrition, Total; Phenylalanine; Reference Standards; Tyrosine; Valine | 1997 |
Attenuation of the protein wasting associated with bed rest by branched-chain amino acids.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Bed Rest; Energy Metabolism; Female; Food, Formulated; Humans; Isoleucine; Leucine; Male; Methylhistidines; Muscle Proteins; Nitrogen; Valine; Wasting Syndrome | 1999 |
The pattern of intracellular free amino acids in granulocytes from hemodialysis patients change to an oral protein supplement (granulocyte amino acids after protein in HD patients).
Topics: Adult; Aged; Amino Acids; Anthropometry; Blood Proteins; Cross-Over Studies; Dietary Proteins; Dietary Supplements; Double-Blind Method; Electric Impedance; Female; Glycine; Granulocytes; Humans; Isoleucine; Male; Middle Aged; Nitrogen; Phenylalanine; Placebos; Renal Dialysis; Somatomedins; Threonine; Tyrosine; Valine | 1999 |
Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Alanine; Amino Acids; Aspartic Acid; Biomarkers; Choline; Corpus Callosum; Female; Humans; Isoleucine; Leucine; Lipoma; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Proteins; Threonine; Valine | 2001 |
BCAA intake affects protein metabolism in muscle after but not during exercise in humans.
Topics: Administration, Oral; Adult; Arteries; Biopsy; Blood Flow Velocity; Exercise Test; Glutamine; Glycogen; Growth Hormone; Heart Rate; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Phenylalanine; Physical Exertion; Proteins; Pulmonary Gas Exchange; Tyrosine; Valine | 2001 |
Results of a phase I trial evaluating a liver support device utilizing albumin dialysis.
Topics: Adolescent; Adult; Ammonia; Bilirubin; Blood Coagulation; Hemodiafiltration; Hepatic Encephalopathy; Humans; Isoleucine; Kidney; Leucine; Liver; Liver Failure, Acute; Middle Aged; Phenylalanine; Serum Albumin; Treatment Outcome; Tyrosine; Valine | 2001 |
Effects of a branched-chain amino acid drink in mania.
Topics: Adult; Amino Acids, Branched-Chain; Analysis of Variance; Beverages; Bipolar Disorder; Humans; Isoleucine; Leucine; Middle Aged; Placebo Effect; Psychiatric Status Rating Scales; Tyrosine; Valine | 2003 |
Concentrations of branched amino acids: isoleucine, valine, leucine in serum of hemodialysis patients during one-year observation.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Female; Humans; Isoleucine; Kidney Diseases; Leucine; Male; Malnutrition; Middle Aged; Renal Dialysis; Serum Albumin; Valine | 2002 |
Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients.
Topics: Adult; Aged; Asian People; China; Cholesterol; Cortisone; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Gene Frequency; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Isoleucine; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Simvastatin; Triglycerides; Valine | 2005 |
Effect of lamivudine therapy on the serum covalently closed-circular (ccc) DNA of chronic hepatitis B infection.
Topics: Adolescent; Adult; Amino Acid Motifs; Anti-HIV Agents; Aspartic Acid; DNA, Circular; DNA, Viral; Female; Follow-Up Studies; Hepatitis B virus; Hepatitis B, Chronic; Humans; Isoleucine; Lamivudine; Male; Methionine; Middle Aged; Mutation; Placebos; Reverse Transcriptase Inhibitors; Tyrosine; Valine; Viral Load | 2005 |
Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial.
Topics: Calcium Channel Blockers; Dietary Supplements; Drug Therapy, Combination; Female; Homocysteine; Hot Flashes; Humans; Isoleucine; Middle Aged; Postmenopause; Severity of Illness Index; Valine | 2008 |
Effects of branched-chain amino acids supplementation on physiological and psychological performance during an offshore sailing race.
Topics: Adult; Amino Acids, Branched-Chain; Dietary Proteins; Dietary Supplements; Drug Combinations; Fatigue; Hand Strength; Heart Rate; Humans; Hydrocortisone; Isoleucine; Leucine; Male; Memory; Physical Endurance; Saliva; Task Performance and Analysis; Valine | 2008 |
Limitations of dietary isoleucine and valine in broiler chick diets.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Isoleucine; Male; Nutrition Policy; Valine; Weight Gain | 2009 |
Valine and isoleucine requirement of 20- to 45-kilogram pigs.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dose-Response Relationship, Drug; Female; Isoleucine; Male; Nutritional Requirements; Swine; Valine | 2012 |
Enhanced anabolic response to milk protein sip feeding in elderly subjects with COPD is associated with a reduced splanchnic extraction of multiple amino acids.
Topics: Administration, Intravenous; Administration, Oral; Aged; Amino Acids, Branched-Chain; Body Composition; Body Weight; Humans; Isoleucine; Leucine; Male; Meals; Middle Aged; Milk Proteins; Phenylalanine; Pulmonary Disease, Chronic Obstructive; Tyrosine; Valine; Whey Proteins; Young Adult | 2012 |
Branched-chain amino acid requirements for enterally fed term neonates in the first month of life.
Topics: Amino Acids, Branched-Chain; Cross-Over Studies; Energy Intake; Female; Gestational Age; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Isoleucine; Leucine; Linear Models; Male; Nutritional Requirements; Oxidation-Reduction; Recommended Dietary Allowances; Valine | 2014 |
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Isoleucine; Leucine; Lysophospholipids; Male; Mass Spectrometry; Metabolome; Metabolomics; Metformin; Middle Aged; Mitochondria; Tyrosine; Valine | 2018 |
The Effect of Lean-Seafood and Non-Seafood Diets on Fasting and Postprandial Serum Metabolites and Lipid Species: Results from a Randomized Crossover Intervention Study in Healthy Adults.
Topics: Adolescent; Adult; Aged; Amino Acids; Biomarkers; Cholesterol; Chromatography, Liquid; Citrates; Cross-Over Studies; Diet; Dietary Fats; Energy Metabolism; Fasting; Female; Humans; Isoleucine; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methylamines; Middle Aged; Postprandial Period; Seafood; Triglycerides; Valine; Young Adult | 2018 |
Effects of leucine supplementation on muscle protein synthesis and degradation pathways in broilers at constant dietary concentrations of isoleucine and valine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Dietary Supplements; Gene Expression Regulation; Isoleucine; Leucine; Male; Muscle Proteins; Muscle, Skeletal; RNA, Messenger; Valine; Weight Gain | 2019 |
Effects on nitrogen balance and metabolism of branched-chain amino acids by growing pigs of supplementing isoleucine and valine to diets with adequate or excess concentrations of dietary leucine.
Topics: Amino Acids, Branched-Chain; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Isoleucine; Leucine; Nitrogen; Swine; Valine | 2020 |
Different Blood Metabolomics Profiles in Infants Consuming a Meat- or Dairy-Based Complementary Diet.
Topics: Amino Acids, Branched-Chain; Amino Acids, Essential; Carnitine; Dairy Products; Diet; Follow-Up Studies; Humans; Infant; Infant Nutritional Physiological Phenomena; Isoleucine; Leucine; Meat; Metabolomics; Phenylalanine; Valine | 2021 |
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine | 2021 |
The effect of Bacillus coagulans Unique IS-2 supplementation on plasma amino acid levels and muscle strength in resistance trained males consuming whey protein: a double-blind, placebo-controlled study.
Topics: Bacillus coagulans; Dietary Supplements; Double-Blind Method; Humans; Isoleucine; Lactose; Leucine; Male; Muscle Strength; Muscle, Skeletal; Powders; Proteins; Resistance Training; Valine; Whey Proteins | 2022 |
Brown adipose tissues mediate the metabolism of branched chain amino acids during the transitioning from hyperthyroidism to euthyroidism (TRIBUTE).
Topics: Adipose Tissue, Brown; Amino Acids, Branched-Chain; Fluorodeoxyglucose F18; Humans; Hyperthyroidism; Insulin; Insulin Resistance; Isoleucine; Leucine; Valine | 2022 |
Postprandial Glucose and Gastrointestinal Hormone Responses of Healthy Subjects to Wheat Biscuits Enriched with L-Arginine or Branched-Chain Amino Acids of Plant Origin.
Topics: Amino Acids, Branched-Chain; Arginine; Blood Glucose; Cross-Over Studies; Gastrointestinal Hormones; Ghrelin; Glicentin; Glucagon-Like Peptide 1; Glucose; Healthy Volunteers; Humans; Insulin; Isoleucine; Leucine; Peptide YY; Postprandial Period; Triticum; Valine | 2022 |
Apparent and standardized ileal amino acid digestibilities of corn, wheat, soybean meal, and corn gluten meal in quail chicks.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Coturnix; Diet; Digestion; Flour; Glutens; Glycine max; Ileum; Isoleucine; Lysine; Methionine; Quail; Threonine; Triticum; Valine; Zea mays | 2023 |
Evaluation of branched-chain amino acid interactions in 10 to 20 kg nursery pigs using a central composite design.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Female; Isoleucine; Leucine; Sus scrofa; Swine; Valine | 2023 |
2126 other study(ies) available for isoleucine and valine
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Factors regulating amino acid release from extrasplanchnic tissues in the rat. Interactions of alanine and glutamine.
Topics: Acetates; Alanine; Alanine Transaminase; Animals; Cycloserine; Depression, Chemical; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hepatectomy; Isoleucine; Leucine; Male; Methionine Sulfoximine; Nephrectomy; Pyruvates; Rats; Starvation; Valine | 1975 |
The existence of three types of acetohydroxy acid synthetase in an isoleucine-requiring mutant of Aerobacter aerogenes.
Topics: Acetolactate Synthase; Enterobacter; Enterobacteriaceae; Enzyme Repression; Flavin-Adenine Dinucleotide; Glucose; Glycerol; Hydrogen-Ion Concentration; Isoleucine; Leucine; Oxo-Acid-Lyases; Phosphates; Valine | 1976 |
Some catalytic and molecular properties of threonine deaminase from Bacillus stearothermophilus.
Topics: Geobacillus stearothermophilus; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Macromolecular Substances; Molecular Weight; Ovalbumin; Temperature; Threonine Dehydratase; Valine | 1976 |
Altered leucyl-transfer RNA synthetase from a mammalian cell culture mutant.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Cell Line; Drug Stability; Enzyme Activation; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Leucine-tRNA Ligase; Magnesium; Mutation; Potassium; RNA, Transfer; Temperature; Valine | 1976 |
The influence of branched chain aminoacids and their ketoderivatives on renal gluconeogenesis.
Topics: Amino Acids; Animals; Calcium; Fructose; Gluconeogenesis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Keto Acids; Kidney Tubules; Kinetics; Lactates; Leucine; Male; Maple Syrup Urine Disease; Oxygen Consumption; Pyruvates; Rats; Succinates; Valine | 1976 |
Effect of valine on propionate metabolism in control and hyperglycinemic fibroblasts and in rat liver.
Topics: Carboxy-Lyases; Fibroblasts; Glycine; Humans; In Vitro Techniques; Isoleucine; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Propionates; Valine | 1977 |
Heterotrophic growth patterns in the unicellular alga Cyanidium caldarium. A possible role for threonine dehydrase.
Topics: Amino Acids; Ammonia; Cell-Free System; Darkness; Enzyme Activation; Glutamates; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Rhodophyta; Succinates; Temperature; Threonine; Threonine Dehydratase; Valine | 1977 |
Alpha-isopropylmalate synthase from Alcaligenes eutrophus H 16. III. Endproduct inhibition and its relief by valine and isoleucine.
Topics: 2-Isopropylmalate Synthase; Alcaligenes; Caproates; Histidine; Hydrogen-Ion Concentration; Isoleucine; Keto Acids; Kinetics; Leucine; Oxo-Acid-Lyases; Temperature; Valine | 1977 |
Inhibition of gluconeogenesis in isolated rat kidney tubules by branched chain alpha-ketoacids.
Topics: Amino Acids, Branched-Chain; Animals; Calcium; Carbon Dioxide; Culture Techniques; Cyclic AMP; Fructose; Gluconeogenesis; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Keto Acids; Kidney Tubules; Lactates; Leucine; Lysine; Male; Pyruvates; Rats; Succinates; Valine | 1978 |
Effects of amino acids on Thiobacillus acidophilus. I. Growth studies with special reference to valine.
Topics: Acetolactate Synthase; Amino Acids; Cell-Free System; Hydrogen-Ion Concentration; Isoleucine; Leucine; Thiobacillus; Valine | 1978 |
Regulation of acetohydroxy acid synthase in streptomycin-dependent Escherichia coli.
Topics: Aconitate Hydratase; Culture Media; Dihydrostreptomycin Sulfate; Enzyme Repression; Escherichia coli; Feedback; Fumarate Hydratase; Glucose; Glucosephosphate Dehydrogenase; Isoleucine; Mutation; Oxo-Acid-Lyases; Streptomycin; Valine | 1975 |
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Female; Isoenzymes; Isoleucine; Kinetics; Leucine; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; Organ Specificity; Rats; Transaminases; Valine | 1975 |
[L-valine transport by the actinomycete Actinomyces species 26-115, the producer of actinomycin C].
Topics: Actinomyces; Amino Acids; Biological Transport; Carbon Radioisotopes; Culture Media; Dactinomycin; Dinitrophenols; Dose-Response Relationship, Drug; Glycols; Isoleucine; Temperature; Valine | 1976 |
Dietary carbohydrate and metabolism of ingested protein.
Topics: Adult; Animals; Blood Glucose; Cattle; Diet; Diet, Reducing; Dietary Carbohydrates; Dietary Proteins; Fasting; Female; Glucagon; Humans; Infusions, Parenteral; Insulin; Isoleucine; Leucine; Male; Meat; Time Factors; Valine | 1979 |
Oral protein and blood branched-chain aminoacids.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Animals; Dietary Proteins; Hip Joint; Humans; Isoleucine; Joint Prosthesis; Leucine; Meat; Surgical Procedures, Operative; Time Factors; Valine | 1979 |
[Aspects of the biosynthesis of actinomycin C].
Topics: Actinomyces; Amino Acids; Autoradiography; Biological Transport; Dactinomycin; Isoleucine; Protoplasts; Valine | 1979 |
Amino acid derangements in patients with sepsis: treatment with branched chain amino acid rich infusions.
Topics: Amino Acids; Blood Glucose; Glucagon; Humans; Insulin; Isoleucine; Leucine; Metabolic Diseases; Parenteral Nutrition; Regression Analysis; Sepsis; Valine | 1978 |
Intracellular free amino acids in patients treated with regular haemodialysis (HD).
Topics: Amino Acids; Amino Acids, Branched-Chain; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Renal Dialysis; Threonine; Uremia; Valine | 1979 |
The effects of sodium arsenate on the free amino acid levels in erythrocytes and plasma in rats.
Topics: Amino Acids; Aminobutyrates; Animals; Arsenates; Arsenic; Aspartic Acid; Betaine; Circadian Rhythm; Erythrocytes; Female; Glutamine; Glycine; Hydroxyproline; Isoleucine; Leucine; Male; Ornithine; Proline; Rats; Serine; Sex Factors; Starvation; Taurine; Valine | 1979 |
Sequential amino acid measurements during experimental diabetic ketoacidosis.
Topics: Alanine; Amino Acids; Animals; Diabetic Ketoacidosis; Erythrocytes; Gluconeogenesis; Glutamates; Isoleucine; Leucine; Male; Plasma; Rats; Streptozocin; Time Factors; Valine | 1975 |
Accumulation of 3-hydroxyisobutyric acid, 2-methyl-3-hydroxybutyric acid and 3-hydroxyisovaleric acid in ketoacidosis.
Topics: Acetates; Acidosis; Animals; Child; Child, Preschool; Chromatography, Gas; Diabetes Mellitus; Diabetic Ketoacidosis; Glutarates; Humans; Hydroxy Acids; Hydroxybutyrates; Infant; Isoleucine; Leucine; Male; Mass Spectrometry; Rats; Streptozocin; Valerates; Valine | 1975 |
The relative importance of muscle protein synthesis and breakdown in the regulation of muscle mass.
Topics: Animals; Diabetes Mellitus; Glucocorticoids; Hypophysectomy; Isoleucine; Leucine; Male; Methionine; Muscle Proteins; Muscles; Rats; RNA, Ribosomal; Starvation; Streptozocin; Valine | 1976 |
[Influence of L-leucine overloading on the level of free amino acids in the diabetic rat].
Topics: Amino Acids; Animals; Corticosterone; Diabetes Mellitus, Experimental; Growth Disorders; Insulin; Insulin Secretion; Isoleucine; Leucine; Liver; Male; Muscles; Rats; Secretory Rate; Valine | 1976 |
Pathway for isoleucine formation form pyruvate by leucine biosynthetic enzymes in leucine-accumulating isoleucine revertants of Serratia marcescens.
Topics: Acetyl Coenzyme A; Butyrates; Coenzyme A; Isoleucine; Leucine; Malates; Maleates; Mutation; Pyruvates; Serratia marcescens; Threonine; Valine | 1977 |
Physical characterization of ilv-lac fusions.
Topics: Bacteriophage lambda; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Isoleucine; Lac Operon; Operon; Recombination, Genetic; Valine | 1979 |
Complement biosynthesis in vitro by rat hepatoma cell strains.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cycloheximide; Erythrocytes; Humans; Hydrocortisone; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Isoleucine; Leucine; Liver Neoplasms; Lysine; Male; Rabbits; Rats; Sheep; Valine | 1975 |
Treatment of carbamyl phosphate synthetase deficiency with keto analogues of essential amino acids.
Topics: Adolescent; Amino Acids; Amino Acids, Essential; Ammonia; Carbamates; Child; Child, Preschool; Circadian Rhythm; Female; Humans; Infant; Infant, Newborn; Injections, Intravenous; Isoleucine; Keto Acids; Leucine; Liver; Methionine; Nitrogen; Phenylalanine; Phosphotransferases; Urea; Valine | 1975 |
Antitumor activity of amino acid derivatives in the primary screening.
Topics: 2-Naphthylamine; Amino Acids; Aminobutyrates; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; Drug Evaluation, Preclinical; HeLa Cells; Isoleucine; Leukemia, Experimental; Liver Neoplasms; Male; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; Sarcoma, Experimental; Structure-Activity Relationship; Tryptophan; Valine | 1975 |
Studies on gluconeogenesis, protein synthesis and cyclic AMP levels in isolated hepatocytes from alloxan diabetic rats.
Topics: Animals; Cyclic AMP; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Fructose; Glucagon; Gluconeogenesis; Histocytochemistry; Isoleucine; Lactates; Lipid Metabolism; Liver; Liver Glycogen; Male; Phenylalanine; Protein Biosynthesis; Rats; Theophylline; Vacuoles; Valine | 1975 |
Long-term management of a case of carbamyl phosphate synthetase deficiency using ketanalogues and hydroxyanalogues of essential amino acids.
Topics: Adolescent; Amino Acids; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Dietary Proteins; Female; Histidine; Humans; Isoleucine; Long-Term Care; Lysine; Methionine; Phenylalanine; Phosphotransferases; Threonine; Tryptophan; Valine | 1976 |
Biochemical characterization of an Escherichia coli hisT strain.
Topics: Amino Acids; Escherichia coli; Genes; Histidinol-Phosphatase; Isoleucine; Leucine; Mutation; RNA, Bacterial; RNA, Transfer; Valine | 1977 |
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Female; Fetus; Humans; In Vitro Techniques; Isoenzymes; Isoleucine; Kidney Neoplasms; Leucine; Liver Neoplasms; Male; Neoplasms; Rats; Species Specificity; Stomach Neoplasms; Substrate Specificity; Tissue Distribution; Transaminases; Valine | 1977 |
Cyclic AMP can replace the relA-dependent requirement for derepression of acetohydroxy acid synthase in E. coli K-12.
Topics: Acetolactate Synthase; Carbon; Cyclic AMP; Energy Metabolism; Enzyme Repression; Escherichia coli; Isoleucine; Mutation; Operon; Oxo-Acid-Lyases; Valine | 1977 |
Threonine deaminase from Escherichia coli. II. Maturation and physical properties of the enzyme from a mutant altered in its regulation of gene expression.
Topics: Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Genes, Regulator; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Macromolecular Substances; Molecular Weight; Mutation; Temperature; Threonine; Time Factors; Ultracentrifugation; Valine | 1975 |
A branched-chain amino acid aminotransferase from the rumen ciliate genus Entodinium.
Topics: Animals; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Ciliophora; Dialysis; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Glutathione; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Leucine; Molecular Weight; Pyridoxal Phosphate; Rumen; Transaminases; Valine | 1975 |
The mechanism of swarming of Vibrio alginolyticus.
Topics: Arginine; Chemotaxis; Culture Media; Flagella; Hydrogen-Ion Concentration; Isoleucine; Malonates; Mutation; Nitrosoguanidines; Propionates; Sodium Chloride; Temperature; Valerates; Valine; Vibrio | 1975 |
Structural specificity of the carrier for L-tryptophan in rat cerebral cortex slices.
Topics: Animals; Biological Transport, Active; Cerebral Cortex; In Vitro Techniques; Isoleucine; Kynurenine; Leucine; Phenylalanine; Rats; Tryptophan; Tyrosine; Valine | 1979 |
Norvaline accumulation by regulatory mutants of Serratia marcescens.
Topics: Cell-Free System; Culture Media; Feedback; Isoleucine; Leucine; Mutation; Serratia marcescens; Threonine Dehydratase; Transduction, Genetic; Valine | 1977 |
Repression and inhibition of transport systems for branched-chain amino acids in Salmonella typhimurium.
Topics: Amino Acids; Biological Transport, Active; Dipeptides; Enzyme Repression; Isoleucine; Keto Acids; Leucine; Mutation; Salmonella typhimurium; Stereoisomerism; Valine | 1977 |
Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Protein Biosynthesis; Pyrophosphatases; RNA, Transfer; Structure-Activity Relationship; Valine | 1977 |
Partial derepression of the isoleucine-valine enzymes during methionine starvation is Salmonella typhimurium.
Topics: 2-Isopropylmalate Synthase; Alcohol Oxidoreductases; Amino Acyl-tRNA Synthetases; Isoleucine; Kinetics; Methionine; Salmonella typhimurium; Threonine Dehydratase; Valine | 1977 |
Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems.
Topics: Biological Transport, Active; Escherichia coli; Genes; Isoleucine; Leucine; Mutation; Serine; Threonine; Threonine Dehydratase; Valine | 1977 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Escherichia coli transport mutants lacking binding protein and other components of the branched-chain amino acid transport systems.
Topics: Amino Acids; Biological Transport, Active; Carrier Proteins; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Genetic Linkage; Isoleucine; Leucine; Mutation; Valine | 1977 |
Use of 3H and 14C double-labeled glucose to assess in vivo pathways of amino acid biosynthesis in Escherichia coli.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Escherichia coli; Glucose; Glutamates; Glycine; Glycolysis; Isoleucine; Leucine; Methionine; Radioactive Tracers; Serine; Tritium; Tyrosine; Valine | 1977 |
Detection of messenger RNA from the isoleucine--valine operons of Salmonella typhimurium by heterologous DNA-RNA hybridization: involvement of transfer RNA in transcriptional repression.
Topics: Coliphages; DNA, Viral; Enzyme Repression; Genes, Regulator; Isoleucine; Mutation; Nucleic Acid Hybridization; Operon; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Salmonella typhimurium; Transcription, Genetic; Valine | 1977 |
The primary structure of a Leu, Ile and Val (LIV)-binding protein from Escherichia coli.
Topics: Amino Acid Sequence; Bacterial Proteins; Carrier Proteins; Escherichia coli; Isoleucine; Leucine; Valine | 1977 |
Breakdown of ppGpp in spoT and spoT-cells of Escherichia coli. Manganese and energy requirement and tetracycline inhibition.
Topics: Dinitrophenols; Dose-Response Relationship, Drug; Escherichia coli; Glucose; Guanine Nucleotides; Isoleucine; Kinetics; Magnesium; Manganese; Mutation; Species Specificity; Tetracycline; Valine | 1977 |
Microcalorimetric study of substrate fixation on the leucine-isoleucine-valine-binding protein from Escherichia coli.
Topics: Biological Transport, Active; Calorimetry; Carrier Proteins; Escherichia coli; Isoleucine; Leucine; Thermodynamics; Valine | 1977 |
Characterization of fusions between the lac operon and the ilv gene cluster in Escherichia coli: ilvC-lac fusions.
Topics: Bacteriological Techniques; Chromosome Mapping; Chromosomes, Bacterial; Coliphages; Escherichia coli; Genes, Regulator; Isoleucine; Lactose; Operon; Transduction, Genetic; Valine | 1977 |
Enhancement of isoleucine hydroxamate-mediated growth inhibition and improvement of isoleucine-producing strains of Serratia marcescens.
Topics: Acetolactate Synthase; Aspartate Kinase; Cell-Free System; Enzyme Repression; Glucose; Glycerol; Homoserine Dehydrogenase; Isoleucine; Leucine; Mutation; Serratia marcescens; Threonine Dehydratase; Transaminases; Valine | 1977 |
Growth inhibition of Escherichia coli K-12 by L-valine: a consequence of a regulatory pattern.
Topics: Acetolactate Synthase; Escherichia coli; Genes; Genes, Regulator; Isoenzymes; Isoleucine; Mutation; Oxo-Acid-Lyases; Valine | 1977 |
Physical organization of the ilvEDAC genes of Escherichia coli strain K-12.
Topics: Chromosome Mapping; Coliphages; DNA Restriction Enzymes; DNA, Recombinant; Escherichia coli; Isoleucine; Valine | 1978 |
Coordination of levels of elongation factors Tu, Ts, and G, and ribosomal protein SI in Escherichia coli.
Topics: Escherichia coli; Guanosine Diphosphate; Isoleucine; Leucine; Peptide Elongation Factors; Ribosomal Proteins; Valine | 1978 |
Branched-chain amino acid transport regulation in mutants blocked in tRNA maturation and transcriptional termination.
Topics: Amino Acids; Biological Transport, Active; Escherichia coli; Genes; Isoleucine; Leucine; Proline; Rho Factor; RNA, Bacterial; RNA, Transfer; Transcription Factors; Valine | 1978 |
relA Gene control of bacterial glycogen synthesis.
Topics: Escherichia coli; Genes; Glycogen; Guanine Nucleotides; Guanosine Tetraphosphate; Isoleucine; Valine | 1978 |
A new locus (leuK) affecting the regulation of branched-chain amino acid, histidine, and tryptophan biosynthetic enzymes.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Galactose; Genes, Regulator; Histidine; Isoleucine; Leucine; Operon; RNA, Bacterial; RNA, Transfer; Tryptophan; Valine | 1978 |
Enhanced allosteric regulation of threonine deaminase and acetohydroxy acid synthase from Escherichia coli in a permeabilized-cell assay system.
Topics: Acetolactate Synthase; Allosteric Regulation; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Escherichia coli; Isoleucine; Oxo-Acid-Lyases; Sonication; Threonine Dehydratase; Valine | 1978 |
Preliminary crystallographic data for a leucine, isoleucine, valine-binding protein from Escherichia coli K12.
Topics: Bacterial Proteins; Carrier Proteins; Crystallography; Escherichia coli; Isoleucine; Leucine; Protein Binding; Valine | 1978 |
Suppressors of a genetic regulatory mutation affecting isoleucine-valine biosynthesis in Escherichia coli K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes, Regulator; Genetic Linkage; Isoleucine; Mutation; Suppression, Genetic; Threonine Dehydratase; Valine | 1978 |
Genetic separation of high- and low-affinity transport systems for branched-chain amino acids in Escherichia coli K-12.
Topics: Biological Transport, Active; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Genetic Linkage; Isoleucine; Leucine; Mutation; Valine | 1978 |
A site of action for tRNA mediated regulation of the ilvOEDA operon of Escherichia coli K12.
Topics: Escherichia coli; Genes; Isoleucine; Mutation; Operon; Rho Factor; RNA, Transfer; Threonine Dehydratase; Valine | 1978 |
Amino acid metabolism in dogs with E. coli bacteremic shock.
Topics: Alanine; Amino Acids; Animals; Blood Gas Analysis; Blood Pressure; Blood Urea Nitrogen; Dogs; Escherichia coli Infections; Glucagon; Glycine; Hypoglycemia; Isoleucine; Lactates; Leucine; Muscles; Shock, Septic; Valine | 1979 |
Regulation of isoleucine and valine biosynthesis in Salmonella typhimurium: the effect of hisU on repression control.
Topics: Genes, Regulator; Isoleucine; Mutation; Salmonella typhimurium; Threonine Dehydratase; Valine | 1979 |
Deletion mapping of the ilvGOEDAC genes of Escherichia coli K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Coliphages; Escherichia coli; Genes; Isoleucine; Leucine; Lysogeny; Transduction, Genetic; Valine | 1979 |
Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli.
Topics: Amino Acids, Branched-Chain; Biological Transport, Active; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Isoleucine; Leucine; Mathematics; Mutation; Valine | 1979 |
Prevention of the immunodepressive effects of excess dietary leucine by isoleucine and valine in the rat.
Topics: Animals; Antibodies; Dietary Proteins; Escherichia coli; Hemagglutinins; Immunoglobulin G; Immunosuppression Therapy; Isoleucine; Lipopolysaccharides; Lymphocytes; Male; Rats; Spleen; Valine | 1979 |
Transaminase B from Escherichia coli: quaternary structure, amino-terminal sequence, substrate specificity, and absence of a separate valine-alpha-ketoglutarate activity.
Topics: Amino Acid Sequence; Amino Acids; Escherichia coli; Isoleucine; Ketoglutaric Acids; Protein Conformation; Substrate Specificity; Transaminases; Valine | 1979 |
ilvU, a locus in Escherichia coli affecting the derepression of isoleucyl-tRNA synthetase and the RPC-5 chromatographic profiles of tRNAIle and tRNAVal.
Topics: Amino Acyl-tRNA Synthetases; Chloramphenicol; Chromatography, High Pressure Liquid; Enzyme Repression; Escherichia coli; Genotype; Isoleucine; Isoleucine-tRNA Ligase; Mutation; Phenotype; RNA, Transfer; Valine | 1979 |
Stereospecificity of the reductoisomerase-catalyzed step in the pathway of biosynthesis of valine and leucine.
Topics: 2-Acetolactate Mutase; Escherichia coli; Isoleucine; Isomerases; Leucine; Pyruvates; Substrate Specificity; Valine | 1979 |
Physiological characterization of polar Tn5-induced isoleucine-valine auxotrophs in Escherichia coli K.12: evidence for an internal promoter in the ilvOGEDA operon.
Topics: DNA Transposable Elements; Escherichia coli; Isoleucine; Mutation; Transaminases; Valine | 1979 |
Multivalent regulation of isoleucine-valine transaminase in an Escherichia coli K-12 ilvA deletion strain.
Topics: Chromosome Deletion; Escherichia coli; Genes; Isoleucine; Threonine Dehydratase; Transaminases; Valine | 1977 |
[Regulation of isoleucine and valine biosynthesis in Bacillus cereus T: possible role of threonine deaminase].
Topics: Bacillus cereus; Hydro-Lyases; Isoleucine; Leucine; Mutation; Threonine Dehydratase; Valine | 1977 |
In vitro synthesis of beta-galactosidase with ilv-lac fusion deoxyribonucleic acid as template.
Topics: beta-Galactosidase; DNA, Bacterial; Enzyme Induction; Escherichia coli; Galactosidases; Genes; Hydroxybutyrates; Isoleucine; Kinetics; Lactose; Protein Biosynthesis; Transcription, Genetic; Valine | 1977 |
Subclinical protein-energy malnutrition in under-privileged Ethiopian mothers and their newborn infants.
Topics: Adolescent; Adult; Developing Countries; Ethiopia; Female; Fetal Blood; Glycine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Methionine; Phenylalanine; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Socioeconomic Factors; Tyrosine; Valine | 1978 |
Plasma neutral amino acids in mania and depression: variation during acute and prolonged treatment with L-tryptophan.
Topics: Amino Acids; Bipolar Disorder; Female; Humans; Isoleucine; Kynurenine; Leucine; Middle Aged; Tryptophan; Tyrosine; Valine | 1979 |
The effect of amino acids on the temperature sensitive phenotype of the mammalian leucyl-tRNA synthetase mutant tsHl and its revertants.
Topics: Amino Acyl-tRNA Synthetases; Animals; Cell Line; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Drug Therapy, Combination; Isoleucine; Leucine; Leucine-tRNA Ligase; Mutation; Phenotype; Temperature; Valine | 1979 |
Thiamine-responsive intermittent branched-chain ketoaciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Child, Preschool; Dietary Proteins; Humans; Isoleucine; Keto Acids; Leucine; Male; Thiamine; Valine | 1979 |
Increased glucagon secretion in protein-fed rats: lack of relationship to plasma amino acids.
Topics: Amino Acids; Animals; Blood Glucose; Dietary Proteins; Fasting; Glucagon; Insulin; Isoleucine; Leucine; Male; Rats; Valine | 1979 |
Changes in the concentrations of branched chain amino acids in the blood in response to alterations in the composition of a hypocaloric diet.
Topics: Adult; Alanine; Blood Glucose; Diet; Energy Intake; Fatty Acids, Nonesterified; Humans; Hydroxybutyrates; Insulin; Isoleucine; Leucine; Male; Valine | 1979 |
Arterial plasma amino acids during the first week following femoral shaft fracture.
Topics: Alanine; Amino Acids; Blood Glucose; Femoral Fractures; Glucagon; Glycine; Humans; Insulin; Isoleucine; Leucine; Time Factors; Valine | 1979 |
Streptozotocin-induced diabetes in rats decreases brain tryptophan uptake after portacaval anastomosis.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Tryptophan; Tyrosine; Valine | 1979 |
Branched chain amino acid aminotransferase isoenzymes of Pseudomonas cepacia.
Topics: Humans; Isoenzymes; Isoleucine; Leucine; Molecular Weight; Pseudomonas; Pseudomonas Infections; Soil Microbiology; Transaminases; Valine | 1979 |
Normal alanine-glucose relationships and their changes in diabetic patients before and after insulin treatment.
Topics: Adult; Aged; Alanine; Blood Glucose; Diabetes Mellitus; Female; Humans; Insulin; Isoleucine; Ketones; Kinetics; Leucine; Male; Middle Aged; Valine | 1979 |
General stimulation of muscle protein synthesis by branched chain amino acids in vitro.
Topics: Animals; Diaphragm; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Isoleucine; Leucine; Male; Muscle Proteins; Muscles; Rats; Tyrosine; Valine | 1979 |
The relation between urinary 5-hydroxyindoleacetic acid levels and the ratio of tryptophan to other large neutral amino acids placed in the stomach.
Topics: Administration, Oral; Animals; Brain; Carbidopa; Hydroxyindoleacetic Acid; Intestine, Small; Isoleucine; Male; Pyridoxine; Rats; Serotonin; Tryptophan; Valine | 1979 |
In vitro effect of branched chain amino acids on the ribosomal cycle in muscles of fasted rats.
Topics: Amino Acids; Animals; Glucose; Insulin; Isoleucine; Leucine; Male; Muscles; Polyribosomes; Rats; Ribosomes; Structure-Activity Relationship; Valine | 1979 |
Cysteine-homocysteine mixed disulphide: differing plasma concentrations in normal men and women.
Topics: Adult; Amino Acids; Cysteine; Cystine; Disulfides; Female; Homocysteine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Valine | 1979 |
Plasma branched-chain amino acids in cold- and heat-acclimatised rats.
Topics: Acclimatization; Animals; Cold Temperature; Hot Temperature; Isoleucine; Leucine; Male; Rats; Valine | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Valine, leucine, and isoleucine metabolism by lactating bovine mammary tissue.
Topics: Acetates; Amino Acids; Animals; Cattle; Female; Glucose; Isoleucine; Keto Acids; Lactation; Leucine; Mammary Glands, Animal; Milk; Milk Proteins; Pregnancy; Valine | 1977 |
Prolongation of G1 and S phase in C-6 glioma cells treated with maple syrup urine disease metabolits. Morphologic and cell cycle studies.
Topics: Caproates; Cell Count; Cell Cycle; Cell Line; Humans; Interphase; Isoleucine; Keto Acids; Kinetics; Leucine; Maple Syrup Urine Disease; Mitosis; Neuroglia; Valine | 1978 |
Factors affecting plasma amino acid concentrations in control subjects.
Topics: Adolescent; Adult; Aged; Amino Acids; Circadian Rhythm; Cystine; Dietary Proteins; Eating; Fasting; Female; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Proline; Sex Factors; Valine | 1979 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein.
Topics: Adult; Aged; Amino Acids; Circadian Rhythm; Dietary Proteins; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Methionine; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Kinetics and mechanism for the conformational transition in p-guanidinobenzoate bovine trypsinogen induced by the isoleucine-valine dipeptide.
Topics: Animals; Benzoates; Cattle; Dipeptides; Guanidines; Isoleucine; Kinetics; Mathematics; Protein Binding; Protein Conformation; Trypsinogen; Valine | 1979 |
The effect of L-alpha-amino-n-butyric acid on growth and production of extracellular isoleucine and valine by Eubacterium ruminantium and a related rumen isolate.
Topics: Adaptation, Physiological; Aminobutyrates; Animals; Bacteria; Eubacterium; Isoleucine; Rumen; Valine | 1979 |
Effect of bound gossypol and amino acid supplementation of glandless cottonseed meal on the growth of weanling rats.
Topics: Amino Acids; Animals; Cottonseed Oil; Dietary Proteins; Gossypol; Isoleucine; Lysine; Male; Methionine; Rats; Threonine; Valine | 1977 |
Thin layer chromatographic analyses of amino acids in Echinostoma revolutum (Trematoda) adults.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Chromatography, Thin Layer; Echinostoma; Isoleucine; Leucine; Methionine; Proline; Serine; Tyrosine; Valine | 1977 |
Effect of valine, leucine & isoleucine on acetoin plus diacetyl formation by bacteria & yeasts.
Topics: Acetoin; Amino Acids, Essential; Butanones; Diacetyl; Enterobacter; Enterobacteriaceae; Fungi; Isoleucine; Leucine; Valine | 1977 |
Effect of different concentrations of dl-isoleucine, dl-valine, and dl-alanine on growth and sporulation in Fusarium oxysporum f. udum (Butl.) Sn. et H.
Topics: Alanine; Fusarium; Isoleucine; Spores, Fungal; Valine | 1977 |
[99mTc-(Sn)-pyridoxylidenevaline and 99mTc-(Sn)-pyridoxylideneisoleucine: potential radiopharmaceuticals for hepatobiliary tract imaging].
Topics: Animals; Biliary Tract; Female; Isoleucine; Liver; Pyridoxal; Radionuclide Imaging; Rats; Technetium; Valine | 1977 |
Increase in large neutral amino acid transport into brain by insulin.
Topics: Amino Acids; Animals; Brain; Fatty Acids, Nonesterified; Glucose; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Tryptophan; Tyrosine; Valine | 1978 |
Branched chain 2-oxo-acid dehydrogenase complex of rat liver.
Topics: Acyl Coenzyme A; Animals; Coenzyme A; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Mitochondria, Liver; Multienzyme Complexes; Rats; Thiamine Pyrophosphate; Valine | 1978 |
Branched chain amino acid metabolism in the retina of diabetic rats.
Topics: Amino Acids; Animals; Diabetes Mellitus, Experimental; Glucose; Insulin; Isoleucine; Leucine; Male; Protein Biosynthesis; Rats; Retina; Valine | 1978 |
The branched-chain amino acid antagonism in chicks.
Topics: Animals; Chickens; Diet; Female; Growth; Isoleucine; Leucine; Male; Polyribosomes; Transaminases; Valine | 1978 |
The neurotoxicity of valine deficiency in rats.
Topics: Animals; Isoleucine; Leucine; Male; Movement Disorders; Nervous System; Rats; Red Nucleus; Tryptophan; Valine | 1978 |
Volatile acid production from threonine, valine, leucine and isoleucine by clostridia.
Topics: Acetates; Butyrates; Caproates; Clostridium; Fatty Acids, Volatile; Isoleucine; Leucine; Propionates; Species Specificity; Threonine; Valerates; Valine | 1978 |
Branched chain amino acids as activators of branched chain ketoacid dehydrogenase.
Topics: Amino Acids, Branched-Chain; Hot Temperature; Isoleucine; Ketone Oxidoreductases; Leucine; Molecular Weight; Pseudomonas; Substrate Specificity; Valine | 1978 |
Neurochemistry of appetite mechanisms.
Topics: Amino Acids; Animals; Appetite; Brain; Dietary Carbohydrates; Dietary Proteins; Epinephrine; Food Preferences; Humans; Hypothalamus; Isoleucine; Norepinephrine; Rats; Serotonin; Sodium; Valine; Vitamins | 1978 |
Plasma ratio of valine, leucine and isoleucine to phenylalanine and tyrosine in liver disease.
Topics: Adult; Amino Acids; Female; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Phenylalanine; Tyrosine; Valine | 1978 |
The diagnosis and management of propionic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Biotin; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Isoleucine; Male; Methionine; Propionates; Threonine; Valine | 1978 |
Absorption of keto-analogues of branched-chain amino acids from rat small intestine.
Topics: Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Glucose; Intestinal Absorption; Intestine, Small; Intubation, Gastrointestinal; Isoleucine; Jejunum; Keto Acids; Leucine; Male; Mathematics; Perfusion; Rats; Sodium Chloride; Valine | 1979 |
Dietary management of maple-sirup-urine disease: extension of equivalency systems.
Topics: Child; Child, Preschool; Cooking; Dietary Proteins; Energy Intake; Humans; Infant; Infant Food; Isoleucine; Leucine; Maple Syrup Urine Disease; Methods; Valine | 1979 |
Transport of sugars and amino acids in bacteria. XVI. Theory and evaluation of a model for the membrane transport reaction mediated by a single carrier with three binding sites for substrate.
Topics: Binding Sites; Biological Transport, Active; Cell Membrane; Escherichia coli; Isoleucine; Kinetics; Models, Biological; Protein Binding; Valine | 1975 |
The phi80 lambdadilv phage and its use to detect messenger RNA related to isoleucine-valine metabolism.
Topics: Binding Sites; Chromosome Mapping; Coliphages; Escherichia coli; Genes; Genotype; Isoleucine; Kinetics; Microscopy, Electron; Mutation; Nucleic Acid Hybridization; Polyribosomes; RNA, Messenger; Valine | 1975 |
Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae.
Topics: Chromosome Mapping; Fungal Proteins; Genes; Genes, Regulator; Hydro-Lyases; Isoleucine; Leucine; Saccharomyces cerevisiae; Threonine Dehydratase; Valine | 1975 |
Binding proteins and membrane transport.
Topics: Biological Transport; Carrier Proteins; Cell Membrane; Chemotaxis; Energy Metabolism; Escherichia coli; Isoleucine; Kinetics; Leucine; Mutation; Valine | 1975 |
Mapping of two loci affecting the regulation of branched-chain amino acid transport in Escherichia coli K-12.
Topics: Biological Transport, Active; Chromosome Mapping; Conjugation, Genetic; Crosses, Genetic; Escherichia coli; Genes, Regulator; Genetic Linkage; Isoleucine; Leucine; Mutation; Protein Binding; Stereoisomerism; Transduction, Genetic; Valine | 1976 |
Isolation of relaxed-control mutants of escherichia coli K-12 which are sensitive to glucose starvation.
Topics: Cell Division; Cell Survival; Chloramphenicol; Escherichia coli; Glucose; Isoleucine; Mutation; Nitrogen; Protein Biosynthesis; Species Specificity; Starvation; Thymine; Transcription, Genetic; Valine | 1976 |
Novel genotypes among transductants made with bacteriophage P1 lysates from an F14 merogenote strain of Escherichia coli K-12.
Topics: Acridines; Arginine; Chromosome Mapping; Coliphages; Conjugation, Genetic; Escherichia coli; F Factor; Genes; Genetic Linkage; Genotype; Isoleucine; Lysogeny; Methionine; RNA Viruses; Transduction, Genetic; Valine | 1976 |
Purification and properties of threonine deaminase from Saccharomyces cerevisiae.
Topics: Hydro-Lyases; Isoleucine; Kinetics; Molecular Weight; Saccharomyces cerevisiae; Stereoisomerism; Threonine Dehydratase; Valine | 1976 |
Regulation of branched-chain amino acid transport in Escherichia coli.
Topics: Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Chloramphenicol; Escherichia coli; Isoleucine; Kinetics; Leucine; Leucine-tRNA Ligase; Threonine Dehydratase; Valine | 1976 |
L-Norvaline and L-homoisoleucine formation by Serratia marcescens,.
Topics: Isoleucine; Magnetic Resonance Spectroscopy; Mutation; Serratia marcescens; Species Specificity; Spectrophotometry, Infrared; Threonine; Valine | 1976 |
Transport of sugars and amino acids in bacteria. XVII. On the existence and nature of substrate amino acids bound to purified branched chain amino acid-binding proteins of Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Biological Transport, Active; Dansyl Compounds; Drug Stability; Escherichia coli; Isoleucine; Kinetics; Leucine; Mathematics; Valine | 1976 |
Hydrolytic action of aminoacyl-tRNA synthetases from baker's yeast: "chemical proofreading" preventing acylation of tRNA(I1e) with misactivated valine.
Topics: Amino Acyl-tRNA Synthetases; Hydrolases; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Phenylalanine-tRNA Ligase; RNA, Transfer; Saccharomyces cerevisiae; Serine-tRNA Ligase; Structure-Activity Relationship; Transfer RNA Aminoacylation; Tyrosine-tRNA Ligase; Valine; Valine-tRNA Ligase | 1976 |
Thialysine-resistant mutant of Salmonella typhimurium with a lesion in the thrA gene.
Topics: Aspartate Kinase; Drug Resistance, Microbial; Homoserine Dehydrogenase; Isoleucine; Lysine; Methionine; Mutation; Salmonella typhimurium; Threonine; Valine | 1976 |
Polarity and the regulation of the ilv gene cluster in Escherichia coli strain K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Genes, Regulator; Isoleucine; Mutation; Operon; Transcription, Genetic; Valine | 1976 |
Biosynthesis of norvaline, norleucine, and homoisoleucine in Serratia marcescens.
Topics: 2-Isopropylmalate Synthase; Aminocaproates; Cell Division; Feedback; Isoleucine; Kinetics; Mutation; Norleucine; Serratia marcescens; Species Specificity; Valine | 1976 |
Thermodynamic studies on the specificity of L-isoleucine-tRNA ligase of Escherichia coli MRE 600. Calorimetric investigations on binding of amino acids and isoleucinol to the enzyme.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Pentanoic Acids; Protein Biosynthesis; Structure-Activity Relationship; Temperature; Thermodynamics; Valine | 1976 |
Regulation of leucine transport and binding proteins in Escherichia coli.
Topics: Biological Transport, Active; Carrier Proteins; Enzyme Repression; Escherichia coli; Genes; Isoleucine; Isoleucine-tRNA Ligase; Leucine; Leucine-tRNA Ligase; Mutation; Protein Binding; Threonine Dehydratase; Valine; Valine-tRNA Ligase | 1976 |
Characterization of a rifampin-resistant, conditional asporogenous mutant of Bacillus subtilis.
Topics: Animals; Arginine; Bacillus subtilis; Chromosome Mapping; DNA-Directed RNA Polymerases; Dogs; Drug Resistance, Microbial; Esterases; Isoleucine; Methionine; Mutation; Peptide Hydrolases; Rifampin; Spores, Bacterial; Temperature; Transformation, Genetic; Valine | 1975 |
The role of plasma amino acids in hepatic encephalopathy.
Topics: Albumins; Amino Acids; Ammonia; Animals; Arginine; Blood Urea Nitrogen; Dogs; Glucose; Glutamates; Hepatic Encephalopathy; Isoleucine; Leucine; Liver Function Tests; Methionine; Parenteral Nutrition; Phenylalanine; Portacaval Shunt, Surgical; Threonine; Tryptophan; Tyrosine; Valine | 1975 |
[Demonstration of a single form of alpha-acetohydroxy acid synthetase in Bacillus cereus T].
Topics: Acetolactate Synthase; Bacillus cereus; Centrifugation, Density Gradient; Enzyme Repression; Escherichia coli; In Vitro Techniques; Isoenzymes; Isoleucine; Leucine; Oxo-Acid-Lyases; Valine | 1975 |
Plasma amino acid changes in the postsurgical newborn during intravenous nutrition with a synthetic amino acid solution.
Topics: Amino Acids; Digestive System Surgical Procedures; Glucose; Glutamates; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Lysine; Nitrogen; Parenteral Nutrition; Postoperative Care; Proline; Valine | 1976 |
Effect of methionine on chemotaxis by Bacillus subtilis.
Topics: Alanine; Bacillus subtilis; Chemotaxis; Isoleucine; Mutation; Uncoupling Agents; Valine | 1976 |
Genetic hybridization of the leu-ilv region in bacilli.
Topics: Bacillus; Bacillus subtilis; Base Sequence; DNA, Bacterial; Genetic Linkage; Isoleucine; Leucine; Transformation, Genetic; Valine | 1976 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
Uptake of branched-chain alpha-keto acids in Bacillus subtilis.
Topics: Bacillus subtilis; Chromosome Mapping; Genes; Isoleucine; Keto Acids; Ketoglutaric Acids; Leucine; Methylnitronitrosoguanidine; Mutagens; Mutation; Pyruvates; Valine | 1976 |
Neonatal citrllinemia: treatment with keto-analogues of essential amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Arginine; Argininosuccinate Synthase; Citrulline; Fibroblasts; Histidine; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1977 |
Mechanism for the incorporation of S-(1,2,3,4-tetrahydro-2-hydroxy-1-naphthyl)-L-cysteine into protein.
Topics: Cysteine; Isoleucine; Polynucleotides; Protein Biosynthesis; Ribosomal Proteins; RNA, Transfer; Valine | 1977 |
The exclusion of L-isoleucine or of L-leucine from the brain of the rat, caused by raised levels of L-valine in the circulation, and the manner in which this exclusion can be partially overcome.
Topics: Animals; Brain; Isoleucine; Leucine; Male; Rats; Time Factors; Valine | 1977 |
Isoleucine requirement of the lactating sow.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Female; Isoleucine; Lactation; Leucine; Milk Proteins; Nitrogen; Nutritional Requirements; Pregnancy; Swine; Valine | 1977 |
Changes in the mixed function oxidase enzymes as a result of individual amino acid deficiencies.
Topics: Aldrin; Animals; Cytochromes; Isoleucine; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Rats; Tryptophan; Valine | 1977 |
Effects of branched-chain amino acid antagonism in the rat on tissue amino acid and keto acid concentrations.
Topics: Alanine; Amino Acids; Animals; Body Weight; Caseins; Dietary Proteins; Glutamates; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Liver; Male; Muscles; Rats; Structure-Activity Relationship; Valine | 1977 |
Quantitative requirement of the hatchling green sea turtle, Chelonia mydas, for valine, leucine, isoleucine and phenylalanine.
Topics: Animals; Diet; Dietary Proteins; Isoleucine; Leucine; Nutritional Requirements; Phenylalanine; Species Specificity; Turtles; Valine | 1977 |
Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids.
Topics: Amino Acids, Essential; Glomerular Filtration Rate; Glycine; Humans; Isoleucine; Leucine; Methionine; Nitrogen; Uremia; Valine | 1977 |
An interaction of leucine, isoleucine and valine in the diet of the growing pig.
Topics: Amino Acids; Animals; Blood Urea Nitrogen; Diet; Isoleucine; Leucine; Nutritional Requirements; Swine; Valine | 1977 |
Hematological and immunological effects of excess dietary leucine in the young rat.
Topics: Animals; Antibodies; Caseins; Dietary Proteins; Hemagglutinins; Hemolysis; Immunosuppressive Agents; Isoleucine; Leucine; Leukocyte Count; Leukocytes; Lymphocytes; Male; Protein Deficiency; Rats; Valine | 1977 |
[Ketotic hypoglycemia in intermittent branch-chain ketoaciduria. Enzymatic and gas chromatographic studies].
Topics: Child; Chromatography, Gas; Female; Fibroblasts; Humans; Hypoglycemia; Isoleucine; Keto Acids; Ketosis; Leucine; Leukocytes; Valine | 1976 |
An analysis of the binding of related ligands.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Glycine; Isoleucine; Ligands; Models, Chemical; Protein Binding; Thermodynamics; Valine | 1976 |
American Academy of Pediatrics. Committee on Nutrition: special diets for infants with inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cysteine; Histidine; Homocystinuria; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Nutritional Requirements; Phenylalanine; Phenylketonurias; Risk; Tyrosine; Valine | 1976 |
Leucine imbalance in corn-soybean meal diets for laying hens.
Topics: Animal Feed; Animals; Chickens; Dietary Proteins; Eggs; Female; Glycine max; Isoleucine; Leucine; Oviposition; Valine; Zea mays | 1976 |
Genetic linkage of chromosomal tetracycline resistance and pigmentation to a purine auxotrophic marker and the isoleucine-valine-leucine structural genes in Staphylococcus aureus.
Topics: Amino Acids; Chromosomes, Bacterial; Drug Resistance, Microbial; Genes; Genetic Linkage; Isoleucine; Leucine; Pigmentation; Purines; Staphylococcus aureus; Tetracycline; Transformation, Genetic; Valine | 1976 |
Stimulation of albumin synthesis by keto analogues of amino acids.
Topics: Albumins; Animals; Dietary Proteins; Hepatectomy; Isoleucine; Keto Acids; Leucine; Liver; Male; Rats; Structure-Activity Relationship; Valine | 1976 |
Regional brain indoleamine metabolism following chronic portacaval anastomosis in the rat.
Topics: Animals; Brain; Disease Models, Animal; Fatty Acids; Histidine; Hydroxyindoleacetic Acid; Hypothalamus; Isoleucine; Leucine; Liver Cirrhosis; Phenylalanine; Portacaval Shunt, Surgical; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1976 |
Electroencephalograms in a case of maple syrup urine disease: their relation to serum levels of branched-chain amino acids.
Topics: Amino Acids, Essential; Brain; Dietary Proteins; Electroencephalography; Humans; Infant; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Valine | 1976 |
Maple syrup urine disease: branched-chain amino acid concentrations and metabolism in cultured human lymphoblasts.
Topics: Adult; Amino Acids; Carboxy-Lyases; Cell Division; Cells, Cultured; Humans; Isoleucine; Leucine; Lymphocytes; Male; Maple Syrup Urine Disease; Valine | 1976 |
Lowering brain phenylalanine levels by giving other large neutral amino acids. A new experimental therapeutic approach to phenylketonuria.
Topics: Amino Acids; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Drug Combinations; Humans; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
[On the circadian changes of concentration of free amino acids in pregnancy (author's transl)].
Topics: Amino Acids; Arginine; Circadian Rhythm; Female; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Pregnancy; Serine; Valine | 1976 |
Leucine, isoleucine and valine interactions in turkey poults.
Topics: Animal Feed; Animals; Isoleucine; Leucine; Male; Turkeys; Valine | 1976 |
Effect of 24 hour fast in obese children.
Topics: Adolescent; Alanine; Blood Glucose; Child; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Insulin; Isoleucine; Ketone Bodies; Leucine; Male; Obesity; Valine | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Purification of tRNATrp, tRNAVal, and partial purification of tRNAIle and tRNAMfet from beef liver.
Topics: Amino Acids; Animals; Cattle; Isoleucine; Liver; Methionine; RNA, Transfer; Tryptophan; Valine | 1976 |
Plasma amino acids in children and adolescents on hemodialysis.
Topics: Adolescent; Amino Acids; Child; Child Nutritional Physiological Phenomena; Citrulline; Diet; Female; Glycine; Growth; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methylhistidines; Nutritional Physiological Phenomena; Proline; Renal Dialysis; Serine; Tyrosine; Valine | 1976 |
[Aminoacid composition of the blood serum in patients with toxic goiter].
Topics: Adolescent; Adult; Alanine; Amino Acids; Female; Goiter; Humans; Hyperthyroidism; Isoleucine; Leucine; Lysine; Male; Middle Aged; Threonine; Tryptophan; Valine | 1976 |
The metabolic effects of glucagon infusion in normoglycaemic and hypoglycaemic small-for-gestational-age infants. II. Changes in plasma amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Citrulline; Glucagon; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Infant, Low Birth Weight; Infant, Newborn; Infant, Small for Gestational Age; Infusions, Parenteral; Isoleucine; Leucine; Liver; Proline; Valine | 1976 |
Isolation of mutants lacking branched-chain amino acid transaminase.
Topics: Cell Line; Enzyme Induction; Isoleucine; Leucine; Mutation; Phenotype; Transaminases; Ultraviolet Rays; Valine | 1976 |
Conditions affecting plasma amino acid patterns in chickens fed practical and purified diets.
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Chickens; Circadian Rhythm; Diet; Food Deprivation; Isoleucine; Lysine; Threonine; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Direct experimental evidence for kinetic proofreading in amino acylation of tRNAIle.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Guanosine Triphosphate; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Peptide Elongation Factors; Valine | 1976 |
Acute reduction of brain serotonin and 5-HIAA following food consumption: correlation with the ratio of serum tryptophan to the sum of competing amino acids.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Diet; Hydroxyindoleacetic Acid; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1975 |
Failure of heavy chain glycosylation of IgG in some patients with common, variable agammaglobulinemia.
Topics: Agammaglobulinemia; B-Lymphocytes; Glucosamine; Humans; Immunoglobulin G; Isoleucine; Leucine; Mannose; Protein Biosynthesis; Valine | 1976 |
Effect of a leu-linked mutation on the valine sensitivity of acetohydroxy acid synthase activity in Escherichia coli.
Topics: Chromosome Mapping; Dipeptides; Enzyme Repression; Escherichia coli; Feedback; Genes; Genetic Linkage; Hydro-Lyases; Isoleucine; Isomerases; Leucine; Mutation; Oxo-Acid-Lyases; Pyruvates; Threonine; Transaminases; Transduction, Genetic; Valine | 1975 |
Mutation affecting regulation of synthesis of acetohydroxy acid synthetase in Escherichia coli K-12.
Topics: Anti-Bacterial Agents; Cell-Free System; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Genes; Hydro-Lyases; Isoleucine; Mutation; Oxo-Acid-Lyases; Pyruvates; Threonine; Transaminases; Transduction, Genetic; Valine | 1975 |
Threonine deaminase from Salmonella typhimurium. Relationship between regulatory sites.
Topics: Allosteric Regulation; Binding Sites; Borohydrides; Hydro-Lyases; Isoleucine; Kinetics; Mathematics; Oxidation-Reduction; Protein Binding; Salmonella typhimurium; Threonine; Valine | 1975 |
Reduced maximal levels of derepression of the isoleucine-valine and leucine enzymes in hisT mutants of Salmonella typhimurium.
Topics: Amino Acyl-tRNA Synthetases; Enzyme Repression; Genes, Regulator; Isoleucine; Leucine; Mutation; Salmonella typhimurium; Valine | 1975 |
Kinetics of unidirectional leucine transport into brain: effects of isoleucine, valine, and anoxia.
Topics: Animals; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Depression, Chemical; Dogs; Hypoxia; Indicator Dilution Techniques; Isoleucine; Kinetics; Leucine; Oxygen; Valine | 1975 |
Regulation of branched-chain aminoacyl-transfer ribonucleic acid synthetases in an ilvDAC deletion strain of Escherichia coli K-12.
Topics: Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Enzyme Repression; Escherichia coli; Genes; Isoleucine; Leucine; Mutation; Valine | 1975 |
The effect of an ilvA Mu phage insertion on ilv gene expression in Escherichia coli K-12.
Topics: Chromosome Mapping; Coliphages; DNA, Viral; Escherichia coli; Genes; Genes, Regulator; Genotype; Isoleucine; Mutation; Recombination, Genetic; Species Specificity; Threonine Dehydratase; Transduction, Genetic; Valerates; Valine | 1975 |
Leucine transport in Escherichia coli. The resolution of multiple transport systems and their coupling to metabolic energy.
Topics: Arsenates; Bacterial Proteins; Binding Sites; Biological Transport, Active; Cell Membrane; Dinitrophenols; Energy Transfer; Escherichia coli; Glucose; Isoleucine; Kinetics; Lactates; Leucine; Mathematics; Mutation; Norleucine; Osmolar Concentration; Protein Binding; Receptors, Drug; Species Specificity; Threonine; Valine | 1975 |
Separate regulation of transport and biosynthesis of leucine, isoleucine, and valine in bacteria.
Topics: Acetolactate Synthase; Alcohol Oxidoreductases; Biological Transport, Active; Cell-Free System; Dicarboxylic Acids; Enzyme Repression; Escherichia coli; Genes, Regulator; Isoleucine; Leucine; Mutation; Protein Binding; Salmonella typhimurium; Valerates; Valine | 1975 |
Isoleucyl-tRNA synthetase from baker's yeast: the 3'-hydroxyl group of the 3'-terminal ribose is essential for preventing misacylation of tRNAIle-C-C-A with misactivated valine.
Topics: Adenine Nucleotides; Amino Acyl-tRNA Synthetases; Binding Sites; Cytosine Nucleotides; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Oligonucleotides; Protein Binding; Ribose; RNA Nucleotidyltransferases; RNA, Transfer; Saccharomyces cerevisiae; Transfer RNA Aminoacylation; Valine | 1975 |
Inhibition of Escherichia coli isoleucine biosynthesis by isoleucine tetrazole.
Topics: 2-Isopropylmalate Synthase; Acetolactate Synthase; Azoles; Depression, Chemical; Drug Resistance, Microbial; Escherichia coli; Homoserine; Isoleucine; Isoleucine-tRNA Ligase; Membrane Transport Proteins; Methionine; Mutation; Peptides; Tetrazoles; Threonine; Threonine Dehydratase; Valine | 1975 |
Transcriptional control of the isoleucine-valine messenger RNA's in E. coli K-12.
Topics: DNA; Escherichia coli; Isoleucine; Mutation; Nucleic Acid Hybridization; Operon; RNA, Bacterial; RNA, Messenger; Valine | 1975 |
[The formation of higher alcohols by amino acid auxotrophic mutants of Saccharomyces cerevisiae. III. Higher alcohols as byproducts of the biosynthesis of amino acids tauthor's transl)].
Topics: 1-Propanol; Alcohols; Amino Acids; Butanols; Ethanol; Isoleucine; Leucine; Mutation; Saccharomyces cerevisiae; Threonine; Valine | 1975 |
Significance of autogenously regulated and constitutive synthesis of regulatory proteins in repressible biosynthetic systems.
Topics: Amino Acids; Arginine; Bacterial Proteins; Enzyme Induction; Enzyme Repression; Escherichia coli; Genes, Regulator; Isoleucine; Models, Biological; Operon; Protein Biosynthesis; Salmonella typhimurium; Transcription, Genetic; Tryptophan; Valine | 1975 |
Role of leucyl-tRNA synthetase in regulation of branched-chain amino-acid transport.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Biological Transport; Escherichia coli; Isoleucine; Kinetics; Leucine; Leucine-tRNA Ligase; Species Specificity; Threonine Dehydratase; Valine | 1975 |
Malabsorption of essential amino acids in tropical sprue.
Topics: Administration, Oral; Adult; Aged; Amino Acids, Essential; Fats; Feces; Folic Acid; Humans; Intestinal Absorption; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Serum Albumin; Sprue, Tropical; Tetracycline; Threonine; Valine; Vitamin B 12; Xylose | 1975 |
Amino acid requirements of growing chickens.
Topics: Amino Acids; Animal Feed; Animals; Arginine; Chickens; Cystine; Dietary Proteins; Glycine; Histidine; Hordeum; Isoleucine; Lysine; Methionine; Nitrogen; Nutritional Requirements; Threonine; Triticum; Tryptophan; Valine | 1975 |
Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm.
Topics: Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Cycloheximide; Diaphragm; Fasting; Glucose; Insulin; Inulin; Isoleucine; Leucine; Male; Methods; Muscle Proteins; Muscles; Rats; Time Factors; Tyrosine; Valine | 1975 |
Effect of growth substrates on morphology of Nocardia corallina.
Topics: Amino Acids; Carboxylic Acids; Cell Division; Culture Media; Disaccharides; Glucose; Hexoses; Isoleucine; Nocardia; Succinates; Valine | 1975 |
Biosynthesis of 3-methylpentacosane in the cockroach Periplaneta americana.
Topics: Acetates; Alkanes; Animals; Carbon Radioisotopes; Chromatography, Gas; Cockroaches; Isoleucine; Lactones; Methionine; Methylmalonic Acid; Mevalonic Acid; Propionates; Tritium; Valine | 1975 |
Maple syrup urine disease. Two cases in Israel.
Topics: Female; Humans; Infant; Isoleucine; Israel; Leucine; Male; Maple Syrup Urine Disease; Pedigree; Peritoneal Dialysis; Valine | 1975 |
Letter: Circular dichroism in the 220-250-nm region of homopolypeptides of aliphatic amino acids in the random-coil conformation in trifluoroacetic acid.
Topics: Alanine; Circular Dichroism; Isoleucine; Leucine; Peptides; Protein Conformation; Spectrum Analysis; Trifluoroacetic Acid; Valine | 1975 |
The beta conformation of polypeptides of valine, isoleucine, and threonine in solution and solid-state: optical and infrared studies.
Topics: Amino Acid Sequence; Isoleucine; Optical Rotatory Dispersion; Peptides; Protein Conformation; Spectrophotometry, Infrared; Threonine; Valine | 1975 |
Factors associated with utilization of the calcium salt of methionine hydroxy analogue by the young chick.
Topics: Amino Acids; Animal Feed; Animals; Body Weight; Calcium; Chickens; Cystine; Fasting; Female; Isoleucine; Leucine; Male; Methionine; Sulfates; Valine | 1975 |
Autoregulation of gene expression.
Topics: Bacteria; Enzyme Induction; Enzyme Repression; Genes, Regulator; Histidine; Isoleucine; Models, Biological; Molecular Biology; Mutation; Tryptophan; Valine | 1975 |
[Disorders of leucine, isoleucine and valine metabolism (maple syrup urine disease)].
Topics: Female; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
[Dipeptidase activity in the small intestine of patients with chronic nonspecific enteritis].
Topics: Adult; Alanine; Chronic Disease; Dipeptidases; Dipeptides; Enteritis; Female; Glutamates; Glycine; Humans; Intestine, Small; Isoleucine; Leucine; Male; Middle Aged; Proline; Valine | 1975 |
Amino acid requirements of the young turkey: leucine, isoleucine and valine.
Topics: Animals; Body Weight; Isoleucine; Leucine; Male; Nutritional Requirements; Turkeys; Valine | 1975 |
Characterization of neutral amino acid transport in a marine pseudomonad.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Glycine; Isoleucine; Kinetics; Leucine; Mutation; Pseudomonas; Seawater; Serine; Stereoisomerism; Threonine; Valine; Water Microbiology | 1975 |
The effect of glucose infusion on the plasma free amino acids in sheep.
Topics: Amino Acids; Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Female; Glucose; Infusions, Parenteral; Isoleucine; Lactation; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Pregnancy; Pregnancy, Animal; Sheep; Valine | 1975 |
Maple syrup urine disease: analysis of branched chain ketoacid decarboxylation in cultured fibroblasts.
Topics: Butyrates; Carboxy-Lyases; Cells, Cultured; Decarboxylation; Fibroblasts; Humans; Infant, Newborn; Isoleucine; Keto Acids; Leucine; Maple Syrup Urine Disease; Multienzyme Complexes; Oxidoreductases; Pentanoic Acids; Pyruvates; Valine | 1975 |
Proceedings: Neonatal diagnosis of maple syrup urine disease and the influence of exchange blood transfusion.
Topics: Exchange Transfusion, Whole Blood; Female; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
Amino acid biosynthesis in mixed rumen cultures.
Topics: Alanine; Amino Acids; Animals; Bacteria; Cattle; Citric Acid Cycle; Female; Fumarates; Isoleucine; Ketoglutaric Acids; Leucine; Lysine; Oxaloacetates; Oxidation-Reduction; Phenylalanine; Propionates; Pyruvates; Rumen; Serine; Tyrosine; Valine | 1975 |
The mutagenic activity of diepoxybutane in yeast.
Topics: Diploidy; Epoxy Compounds; Erythritol; Ethers, Cyclic; Isoleucine; Mutagens; Saccharomyces; Time Factors; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
Regulatory role of dietary leucine on plasma branched-chain amino acid levels in young men.
Topics: Adolescent; Adult; Amino Acids; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Humans; Isoleucine; Leucine; Male; Valine | 1976 |
[Intermittent branched--chain ketoacidurie in ketotic hypoglycemia: investigations to localize the biochemical defect (author's transl)].
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child; Female; Fibroblasts; Humans; Hypoglycemia; Intellectual Disability; Isoleucine; Keto Acids; Ketosis; Leucine; Leukocytes; Valine | 1976 |
Genetic mapping of leucine and isoleucine-valine loci in Rhizobium japonicum.
Topics: Chromosome Mapping; Genes; Genetic Linkage; Isoleucine; Leucine; Mutation; Rhizobium; Transformation, Genetic; Valine | 1976 |
Biosynthesis of internally branched monomethylalkanes in the cockroach Periplaneta fuliginosa.
Topics: Acetates; Alkanes; Animals; Chromatography, Gas; Cockroaches; Glucose; Isoleucine; Methionine; Methylmalonic Acid; Propionates; Skin; Valine | 1976 |
Blood-brain barrier transfer of L-Trp and alpha-MTrp in Li-treated rats.
Topics: Animals; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Isoleucine; Leucine; Lithium; Rats; Tryptophan; Valine | 1992 |
Steric and hydrophobic determinants of the solubilities of recombinant sickle cell hemoglobins.
Topics: Alanine; Escherichia coli; Glutamates; Glutamic Acid; Hemoglobin, Sickle; Humans; Isoleucine; Mutagenesis, Site-Directed; Oxygen; Protein Conformation; Protein Engineering; Recombinant Proteins; Solubility; Structure-Activity Relationship; Valine | 1992 |
Effect of ammonium ions on spiramycin biosynthesis in Streptomyces ambofaciens.
Topics: Amino Acid Oxidoreductases; Ammonia; Biotechnology; Fermentation; Isoleucine; Microbiological Techniques; Spiramycin; Streptomyces; Valine | 1992 |
Glycine and beta-branched residues support and modulate peptide helicity in membrane environments.
Topics: Amino Acid Sequence; Circular Dichroism; Glycine; Isoleucine; Molecular Sequence Data; Peptides; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Threonine; Valine | 1992 |
Secretory pathway of beta/A4 amyloid protein precursor in familial Alzheimer's disease with Val717 to Ile mutation.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Blotting, Western; Cells, Cultured; Humans; Isoleucine; Mutation; Nervous System Diseases; Valine | 1992 |
Valine deficiency. 1. The effect of feeding a valine-deficient diet during the starter period on performance and feather structure of male broiler chicks.
Topics: Amino Acids, Branched-Chain; Animal Nutritional Physiological Phenomena; Animals; Chickens; Feathers; Isoleucine; Leucine; Male; Valine; Weight Gain | 1992 |
Effect of inorganic pyrophosphate on the pretransfer proofreading in the isoleucyl-tRNA synthetase from Escherichia coli.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Phosphates; Protein Conformation; RNA, Transfer, Ile; Valine | 1992 |
Leucine and serine induce mecillinam resistance in Escherichia coli.
Topics: Amdinocillin; Cysteine; Escherichia coli; Genes, Bacterial; Guanosine Tetraphosphate; Isoleucine; Leucine; Penicillin Resistance; Serine; Valine | 1992 |
Effects of the flrA regulatory locus on biosynthesis and excretion of amino acids in Escherichia coli B/r.
Topics: 2-Isopropylmalate Synthase; Alanine; Amino Acids; Escherichia coli; Genes, Bacterial; Genes, Regulator; Isoleucine; Leucine; RNA, Transfer, Leu; Transfer RNA Aminoacylation; Valine | 1992 |
The role of packing interactions in stabilizing folded proteins.
Topics: Isoleucine; Mutation; Protein Conformation; Ribonuclease T1; Thermodynamics; Valine | 1992 |
An enzymatic method for the estimation of L-leucine in rat blood.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Isoleucine; Leucine; Rats; Rats, Inbred Strains; RNA, Transfer, Leu; Scintillation Counting; Valine | 1992 |
DNA topology-mediated regulation of transcription initiation from the tandem promoters of the ilvGMEDA operon of Escherichia coli.
Topics: Bacterial Proteins; Base Sequence; Binding, Competitive; DNA Mutational Analysis; DNA-Binding Proteins; DNA-Directed RNA Polymerases; DNA, Bacterial; Gene Expression Regulation, Bacterial; Integration Host Factors; Isoleucine; Leucine; Molecular Sequence Data; Nucleic Acid Conformation; Operon; Promoter Regions, Genetic; Repressor Proteins; Restriction Mapping; Transcription, Genetic; Valine | 1992 |
Isoleucine requirements of the chicken: the effect of excess leucine and valine on the response to isoleucine.
Topics: Animal Feed; Animals; Body Composition; Chickens; Eating; Female; Isoleucine; Leucine; Lipids; Male; Regression Analysis; Valine; Weight Gain | 1992 |
Transcriptional regulation of the ilv-leu operon of Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Base Sequence; DNA Mutational Analysis; Gene Expression Regulation, Bacterial; Half-Life; Isoleucine; Leucine; Molecular Sequence Data; Nucleic Acid Conformation; Operon; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Terminator Regions, Genetic; Transcription, Genetic; Valine | 1992 |
Identification of Hb Hamilton or beta 11(A8)Val----Ile gene by the polymerase chain reaction amplification technique.
Topics: Base Sequence; Genes; Hemoglobins, Abnormal; Humans; Isoleucine; Molecular Sequence Data; Polymerase Chain Reaction; Valine | 1992 |
Multiple transcripts encoded by the ilvGMEDA gene cluster of Escherichia coli K-12.
Topics: Escherichia coli; Genes, Bacterial; Isoleucine; Leucine; Multigene Family; Transcription, Genetic; Valine | 1992 |
Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Base Sequence; DNA; DNA Mutational Analysis; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Recombination, Genetic; Valine | 1992 |
Isoleucine requirement of broiler chicks as affected by the concentrations of leucine and valine in practical diets.
Topics: Analysis of Variance; Animal Feed; Animals; Chickens; Eating; Isoleucine; Leucine; Random Allocation; Regression Analysis; Valine; Weight Gain | 1992 |
Methylmalonic acid metabolism and nervous-system fatty acids in cobalamin-deficient fruit bats receiving supplements of methionine, valine and isoleucine.
Topics: Amino Acids; Animals; Brain; Chiroptera; Fatty Acids; Isoleucine; Liver; Methionine; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Nervous System; Nervous System Diseases; Spinal Cord; Valine; Vitamin B 12 Deficiency | 1991 |
G to A polymorphism at amino acid codon 655 of the human erbB-2/HER2 gene.
Topics: Alleles; Base Sequence; Chromosomes, Human, Pair 17; Codon; Deoxyribonucleases, Type II Site-Specific; Humans; Isoleucine; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; Valine | 1991 |
Mutation of Glu693 to Gln or Val717 to Ile has no effect on the processing of Alzheimer amyloid precursor protein expressed in COS-1 cells by cDNA transfection.
Topics: Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Cell Line; Cloning, Molecular; Glutamates; Glutamic Acid; Glutamine; Humans; Immunoblotting; Isoleucine; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Transfection; Valine | 1991 |
Conversion of ammonia or urea into essential amino acids, L-leucine, L-valine, and L-isoleucine, using artificial cells containing an immobilized multienzyme system and dextran-NAD+. 2. Yeast alcohol dehydrogenase for coenzyme recycling.
Topics: Alcohol Dehydrogenase; Amino Acids, Essential; Ammonia; Biotechnology; Capsules; Dextrans; Enzymes, Immobilized; Hydrogen-Ion Concentration; Isoleucine; Leucine; NAD; Substrate Specificity; Urea; Valine | 1990 |
Conversion of ammonia or urea into essential amino acids, L-leucine, L-valine, and L-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD. L-lactic dehydrogenase for coenzyme recycling.
Topics: Amino Acid Oxidoreductases; Amino Acids, Essential; Ammonia; Coenzymes; Dextrans; Enzyme Stability; Enzymes, Immobilized; Isoleucine; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Leucine; Leucine Dehydrogenase; NAD; Urea; Urease; Valine | 1990 |
A specific test for transthyretin 122 (Val----Ile), based on PCR-primer-introduced restriction analysis (PCR-PIRA): confirmation of the gene frequency in blacks.
Topics: Alleles; Amyloidosis; Base Sequence; Black People; Cardiomyopathies; Deoxyribonucleases, Type II Site-Specific; DNA; Homozygote; Humans; Isoleucine; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Prealbumin; Restriction Mapping; Valine | 1992 |
The product of the Rhizobium meliloti ilvC gene is required for isoleucine and valine synthesis and nodulation of alfalfa.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Isoleucine; Ketol-Acid Reductoisomerase; Medicago sativa; Molecular Sequence Data; Nitrogen Fixation; Phenotype; Sequence Alignment; Sinorhizobium meliloti; Valine | 1991 |
Tryptophan and neutral amino acids in premenstrual syndrome.
Topics: Adult; Female; Follicular Phase; Humans; Isoleucine; Leucine; Luteal Phase; Phenylalanine; Premenstrual Syndrome; Tryptophan; Tyrosine; Valine | 1991 |
A high-affinity uptake system for branched-chain amino acids in Saccharomyces cerevisiae.
Topics: Amino Acids, Branched-Chain; Biological Transport; Culture Media; Isoleucine; Kinetics; Leucine; Mutation; Saccharomyces cerevisiae; Valine | 1991 |
Evidence for isoleucine as a positive effector of the ilvBN operon in Salmonella typhimurium.
Topics: Acetolactate Synthase; Isoleucine; Kinetics; Mutagenesis; Operon; Salmonella typhimurium; Valine | 1991 |
[The effect of metabolites of the propionate pathway on the oxidative activity of liver mitochondria].
Topics: Animals; Isoleucine; Malonates; Methionine; Mitochondria, Liver; Oxidation-Reduction; Palmitoylcarnitine; Propionates; Rats; Rats, Inbred Strains; Rotenone; Succinates; Succinic Acid; Valine | 1991 |
Isolation of the braZ gene encoding the carrier for a novel branched-chain amino acid transport system in Pseudomonas aeruginosa PAO.
Topics: Amino Acid Sequence; Amino Acids, Branched-Chain; Bacterial Proteins; Base Sequence; Cloning, Molecular; Genes, Bacterial; Isoleucine; Kinetics; Leucine; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Pseudomonas aeruginosa; Valine | 1991 |
Expression and characterization of human factor IX. Factor IXthr-397 and factor IXval-397.
Topics: Base Sequence; Blood Coagulation; Cells, Cultured; Computer Simulation; DNA; Electrophoresis, Polyacrylamide Gel; Factor IX; Factor IXa; Gene Expression Regulation; Humans; Isoleucine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Threonine; Transfection; Valine | 1991 |
The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Base Sequence; Ethnicity; Exons; Female; Humans; Isoleucine; Japan; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Pedigree; Polymerase Chain Reaction; Protein Precursors; Valine; White People | 1991 |
Concentrations of amino acids in the plasma of neonatal foals with septicemia.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Female; Glycine; Gram-Negative Bacteria; Horse Diseases; Horses; Immunoglobulin G; Isoleucine; Male; Phenylalanine; Proline; Sepsis; Threonine; Valine | 1991 |
The effect of plasma valine, isoleucine and leucine on the control of the flux through tyrosine- and tryptophan-hydroxylase in the brain.
Topics: Blood-Brain Barrier; Brain; Food, Formulated; Humans; Isoleucine; Leucine; Phenylketonurias; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase; Valine | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Isolation and characterization of ilvA, ilvBN, and ilvD mutants of Caulobacter crescentus.
Topics: Acetolactate Synthase; Bacteria; Blotting, Southern; Drug Resistance, Microbial; Genetic Complementation Test; Herbicides; Hydro-Lyases; Isoleucine; Methionine; Mutation; Recombination, Genetic; Sulfonylurea Compounds; Threonine Dehydratase; Transduction, Genetic; Valine | 1991 |
Sequence and transcriptional activity of the Escherichia coli K-12 chromosome region between rrnC and ilvGMEDA.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Blotting, Northern; Chromosome Mapping; Chromosomes, Bacterial; Codon; Escherichia coli; Escherichia coli Proteins; Isoleucine; Molecular Sequence Data; Open Reading Frames; Restriction Mapping; Transcription, Genetic; Valine | 1991 |
Leucine-induced amino acid antagonism in rats: muscle valine metabolism and growth impairment.
Topics: Animals; Body Weight; Diet; Insulin; Isoleucine; Leucine; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Valine | 1991 |
Cloning, expression, purification, and characterization of biosynthetic threonine deaminase from Escherichia coli.
Topics: Ammonium Chloride; Base Sequence; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Isoleucine; Kinetics; Molecular Sequence Data; Mutagenesis; Plasmids; Threonine Dehydratase; Valine | 1991 |
Anticodon-dependent aminoacylation of a noncognate tRNA with isoleucine, valine, and phenylalanine in vivo.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Base Sequence; Escherichia coli; In Vitro Techniques; Isoleucine; Isoleucine-tRNA Ligase; Molecular Sequence Data; Peptide Chain Initiation, Translational; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer, Met; Substrate Specificity; Valine; Valine-tRNA Ligase | 1991 |
Nuclear overhauser effect studies of the conformations of Mg(alpha, beta-methylene)ATP bound to E. coli isoleucyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Binding Sites; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Valine | 1991 |
Acute C-peptide, insulin and branched chain amino acid response to feeding in formula and breast fed infants.
Topics: Amino Acids, Branched-Chain; Blood Glucose; Breast Feeding; C-Peptide; Creatinine; Female; Glycine; Humans; Infant; Infant Food; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Milk, Human; Valine | 1991 |
Straight-chain non-polar amino acids are good helix-formers in water.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Circular Dichroism; Isoleucine; Leucine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Conformation; Valine; Water | 1991 |
Two-dimensional NMR studies of staphylococcal nuclease. 1. Sequence-specific assignments of hydrogen-1 signals and solution structure of the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex.
Topics: Alanine; Amino Acid Sequence; Calcium; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Molecular Sequence Data; Molecular Structure; Protein Conformation; Serine; Solutions; Threonine; Thymine Nucleotides; Valine | 1990 |
Evaluation of branched-chain amino acid intake in children with maple syrup urine disease and methylmalonic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Body Weight; Child, Preschool; Creatinine; Dietary Proteins; Female; Food, Formulated; Growth; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Malonates; Maple Syrup Urine Disease; Methylmalonic Acid; Nutritional Requirements; Valine | 1990 |
On the mechanism of L-alloisoleucine formation: studies on a healthy subject and in fibroblasts from normals and patients with maple syrup urine disease.
Topics: Amino Acids, Branched-Chain; Cells, Cultured; Creatinine; Culture Media; Fibroblasts; Humans; Isoleucine; Keto Acids; Least-Squares Analysis; Leucine; Maple Syrup Urine Disease; Metabolic Clearance Rate; Reference Values; Skin; Stereoisomerism; Valine | 1990 |
Analysis of regulation of the ilvGMEDA operon by using leader-attenuator-galK gene fusions.
Topics: Cloning, Molecular; Escherichia coli; Galactokinase; Gene Expression Regulation, Bacterial; Genes, Regulator; Isoleucine; Leucine; Operon; Plasmids; Protein Sorting Signals; RNA, Messenger; Transcription, Genetic; Valine | 1990 |
Acetohydroxy acid synthase activity from a mutation at ilvF in Escherichia coli K-12.
Topics: Acetolactate Synthase; Chromosome Mapping; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Molecular Weight; Mutation; Oxo-Acid-Lyases; Valine | 1990 |
Characterization of the integration host factor binding site in the ilvPG1 promoter region of the ilvGMEDA operon of Escherichia coli.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli; Integration Host Factors; Isoleucine; Molecular Sequence Data; Nucleic Acid Conformation; Operon; Promoter Regions, Genetic; Sulfuric Acid Esters; Valine | 1990 |
Branched chain amino acid regulation of the ILV2 locus in Saccharomyces cerevisiae.
Topics: Gene Expression Regulation, Enzymologic; Isoleucine; Leucine; Saccharomyces cerevisiae; Valine | 1990 |
Fidelity in the aminoacylation of tRNA(Val) with hydroxy analogues of valine, leucine, and isoleucine by valyl-tRNA synthetases from Saccharomyces cerevisiae and Escherichia coli.
Topics: Amino Acids; Escherichia coli; Hydrolysis; Hydroxides; Isoleucine; Leucine; Protein Biosynthesis; RNA, Transfer, Val; Saccharomyces cerevisiae; Valine; Valine-tRNA Ligase | 1990 |
A Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB.
Topics: Animals; Cell Line; Cells, Cultured; Gene Expression; Genes, Viral; Isoleucine; Mice; Mice, Inbred Strains; Moloney murine leukemia virus; Mutation; Nucleic Acid Hybridization; Protein Precursors; Protein Processing, Post-Translational; Restriction Mapping; Species Specificity; Temperature; Transfection; Valine; Viral Envelope Proteins; Virulence | 1990 |
A conserved cleavage-site motif in chloroplast transit peptides.
Topics: Alanine; Amino Acid Sequence; Arginine; Carrier Proteins; Chloroplasts; Cysteine; Isoleucine; Molecular Sequence Data; Plant Proteins; Valine | 1990 |
Activation of branched-chain alpha-keto acid dehydrogenase complex by exercise: effect of high-fat diet intake.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Dietary Carbohydrates; Dietary Fats; Female; Isoleucine; Ketone Oxidoreductases; Leucine; Liver; Male; Multienzyme Complexes; Muscles; Physical Exertion; Rats; Rats, Inbred Strains; Valine | 1990 |
Relative helix-forming tendencies of nonpolar amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Hydrogen-Ion Concentration; Isoleucine; Leucine; Molecular Sequence Data; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Valine | 1990 |
Optimal dietary substitution of racemic ketoanalogues for isoleucine in growing normal and uremic rats.
Topics: Amino Acids, Essential; Animals; Body Weight; Isoleucine; Keto Acids; Male; Nitrogen; Nutritional Requirements; Rats; Rats, Inbred Strains; Urea; Uremia; Valine | 1990 |
Transport of leucine, isoleucine and valine by luminal membrane vesicles from rabbit proximal tubule.
Topics: Amino Acids; Animals; Biological Transport; Carbocyanines; Cell Membrane; Female; Fluorescent Dyes; In Vitro Techniques; Isoleucine; Isomerism; Kidney Tubules, Proximal; Leucine; Male; Potassium Chloride; Rabbits; Sodium Chloride; Time Factors; Valine | 1990 |
Dietary requirements of leucine, isoleucine, and valine in male broilers during the starter period.
Topics: Animal Feed; Animals; Chickens; Diet; Isoleucine; Leucine; Male; Regression Analysis; Valine; Weight Gain | 1990 |
Both valine and isoleucine supplementation delay the development of neurological impairment in vitamin B12 deficient bats.
Topics: Animals; Body Weight; Chiroptera; Isoleucine; Nervous System Diseases; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Examination of the internal promoter, PE, in the ilvGMEDA operon of E. coli K-12.
Topics: DNA, Bacterial; Endonucleases; Escherichia coli; Genes, Bacterial; Isoleucine; Operon; Promoter Regions, Genetic; RNA, Bacterial; RNA, Messenger; Single-Strand Specific DNA and RNA Endonucleases; Transcription, Genetic; Valine | 1986 |
HB F-Tokyo or alpha 2G gamma 234 (B16) Val----Ile found in a newborn baby in Japan.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fetal Hemoglobin; Hemoglobins, Abnormal; Humans; Infant, Newborn; Isoleucine; Japan; Male; Valine | 1986 |
Physical identification of an internal promoter, ilvAp, in the distal portion of the ilvGMEDA operon.
Topics: Base Sequence; Culture Media; DNA, Bacterial; DNA, Recombinant; Endonucleases; Escherichia coli; Galactokinase; Genes, Bacterial; Isoleucine; Leucine; Molecular Sequence Data; Operon; Oxygen; Phenotype; Plasmids; Promoter Regions, Genetic; RNA, Bacterial; Salmonella typhimurium; Sequence Homology, Nucleic Acid; Single-Strand Specific DNA and RNA Endonucleases; Threonine Dehydratase; Valine | 1989 |
Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase).
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Decanoic Acids; DNA; Isoleucine; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Progesterone; Rabbits; Saccharomyces cerevisiae; Serine; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Testosterone; Threonine; Transformation, Genetic; Valine | 1989 |
[Maple syrup urine disease and cystathioninemia].
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Enteral Nutrition; Follow-Up Studies; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Parenteral Nutrition, Total; Valine | 1989 |
[A clinical study of amino acid metabolism in cancerous hypoproteinemia--the role of branched chain amino acids (BCAA) and appropriate compositions of BCAA in parenteral nutrition].
Topics: Amino Acids; Amino Acids, Branched-Chain; Female; Humans; Hypoproteinemia; Isoleucine; Leucine; Male; Middle Aged; Neoplasms; Nitrogen; Parenteral Nutrition, Total; Prealbumin; Retinol-Binding Proteins; Transferrin; Valine | 1989 |
Contribution of aminoacid catabolism to propionate production in methylmalonic acidaemia.
Topics: Acyl Coenzyme A; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Humans; Isoleucine; Kinetics; Leucine; Malonates; Methionine; Methylmalonic Acid; Phenylalanine; Threonine; Time Factors; Valine | 1989 |
Synthesis of 4% Glu-containing Val1 and Ile1-polypentapeptides: model protein systems for demonstrating mechanochemical coupling.
Topics: Glutamates; Glutamic Acid; Indicators and Reagents; Isoleucine; Magnetic Resonance Spectroscopy; Peptides; Valine | 1989 |
Studies on methylmalonic acid in humans. I. Concentrations in serum and urinary excretion in normal subjects after feeding and during fasting, and after loading with protein, fat, sugar, isoleucine, and valine.
Topics: Adult; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Fasting; Female; Humans; Isoleucine; Male; Malonates; Methylmalonic Acid; Middle Aged; Monitoring, Physiologic; Stress, Physiological; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1989 |
Analysis of maple syrup urine disease in cell culture: use of substrates.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Cells, Cultured; Fibroblasts; Hemiterpenes; Humans; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Maple Syrup Urine Disease; Multienzyme Complexes; Substrate Specificity; Valine | 1989 |
Sodium-dependent transport of branched-chain amino acids by a monensin-sensitive ruminal peptostreptococcus.
Topics: Amino Acids, Branched-Chain; Animals; Binding Sites; Biological Transport; Cattle; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Membrane Potentials; Monensin; Peptostreptococcus; Potassium; Rumen; Sodium; Valine | 1989 |
Diurnal rhythm in absolute and relative concentrations of large neutral amino acids in human plasma.
Topics: Adult; Amino Acids; Circadian Rhythm; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Reference Values; Tryptophan; Tyrosine; Valine | 1989 |
Neutral amino acid plasma levels in healthy subjects: effect of complex carbohydrate consumed along with protein.
Topics: Adult; Amino Acids; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Female; Humans; Insulin; Isoleucine; Kinetics; Leucine; Phenylalanine; Reference Values; Tryptophan; Tyrosine; Valine | 1989 |
Transport of branched-chain amino acids in Corynebacterium glutamicum.
Topics: Amino Acids, Branched-Chain; Anaerobiosis; Biological Transport, Active; Corynebacterium; Hydrogen-Ion Concentration; Isoleucine; Leucine; Membrane Potentials; Sodium; Temperature; Valine | 1989 |
Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.
Topics: Amino Acids; Humans; Isoleucine; Leucine; Methionine; Phenylalanine; Physical Exertion; Reference Values; Running; Tryptophan; Tyrosine; Valine | 1989 |
NMR studies of the influence of dodecyl sulfate on the amide hydrogen exchange kinetics of a micelle-solubilized hydrophobic tripeptide.
Topics: Amides; Colloids; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Micelles; Models, Biological; Oligopeptides; Sodium Dodecyl Sulfate; Valine | 1989 |
A post-column immobilized leucine dehydrogenase reactor for determination of branched chain amino acids by high-performance liquid chromatography with fluorescence detection.
Topics: Amino Acid Oxidoreductases; Amino Acids, Branched-Chain; Chromatography, High Pressure Liquid; Enzymes, Immobilized; Hydrogen-Ion Concentration; Isoleucine; Leucine; Leucine Dehydrogenase; Spectrometry, Fluorescence; Valine | 1989 |
Role of brain tyrosine availability in mediating differences in ethanol sensitivity in long-sleep and short-sleep mice.
Topics: Animals; Body Temperature; Brain Chemistry; Catecholamines; Ethanol; Female; Hydroxylation; Isoleucine; Leucine; Male; Mice; Sleep; Tyrosine; Valine | 1989 |
Regulation of leucine transport and oxidation in peripheral human lymphocytes by glutamine.
Topics: Biological Transport; Female; Glutamine; Humans; Isoleucine; Kinetics; Leucine; Lymphocytes; Male; Oxidation-Reduction; Valine | 1989 |
Is increased ammonia liberation after bleeding in the digestive tract the consequence of complete absence of isoleucine in hemoglobin? A study in pigs.
Topics: Alanine; Ammonia; Animals; Blood Flow Velocity; Female; Gastrointestinal Hemorrhage; Glutamine; Hemoglobins; Intestinal Absorption; Intestine, Small; Isoleucine; Leucine; Liver Circulation; Regional Blood Flow; Swine; Urea; Valine | 1989 |
Beta-adrenergic control of brain uptake of large neutral amino acids.
Topics: Amino Acids; Animals; Biological Transport; Brain; Isoleucine; Isoproterenol; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tryptophan; Tyrosine; Valine | 1988 |
Serum valine, methionine and isoleucine levels in patients anaesthetized with and without nitrous oxide.
Topics: Adolescent; Adult; Aged; Anesthesia; Cobamides; Female; Humans; Isoleucine; Male; Methionine; Methylmalonyl-CoA Mutase; Middle Aged; Nitrous Oxide; Valine | 1985 |
An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Aspartic Acid; Binding Sites; Factor VIII; Glutamates; Glutamic Acid; Isoleucine; Valine; von Willebrand Factor | 1988 |
Assessment of effects of amino acids and branched chain keto acids on leucine oxidation in human lymphocytes.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adolescent; Adult; Alanine; Amino Acids; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Lymphocytes; Male; Middle Aged; Multienzyme Complexes; Oxidation-Reduction; Valine | 1988 |
Regulation of branched-chain 2-oxo acid dehydrogenase activity during exercise.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Muscles; Physical Exertion; Rats; Rats, Inbred Strains; Valine | 1989 |
Metabolism of branched-chain amino acids in leg muscles from tail-cast suspended intact and adrenalectomized rats.
Topics: Adrenalectomy; Amino Acids, Branched-Chain; Animals; Female; Hindlimb; Isoleucine; Leucine; Muscles; Posture; Rats; Rats, Inbred Strains; Reference Values; Valine | 1989 |
Physical analysis of deletion mutations in the ilvGEDA operon of Escherichia coli K-12.
Topics: Chromosome Deletion; Chromosome Mapping; DNA Restriction Enzymes; Escherichia coli; Genes, Bacterial; Isoleucine; Mutation; Nucleic Acid Hybridization; Operon; Valine | 1985 |
Restriction endonuclease analysis of the ilvGEDA operon of members of the family Enterobacteriaceae.
Topics: Base Sequence; DNA Restriction Enzymes; DNA, Bacterial; Enterobacteriaceae; Isoleucine; Operon; Valine | 1985 |
Analysis and comparison of the internal promoter, pE, of the ilvGMEDA operons from Escherichia coli K-12 and Salmonella typhimurium.
Topics: Chromosome Mapping; DNA, Bacterial; Endonucleases; Escherichia coli; Galactokinase; Genes, Bacterial; Isoleucine; Operon; Promoter Regions, Genetic; Salmonella typhimurium; Sequence Homology, Nucleic Acid; Single-Strand Specific DNA and RNA Endonucleases; Transaminases; Transcription, Genetic; Valine | 1986 |
Coronavirus IBV: partial amino terminal sequencing of spike polypeptide S2 identifies the sequence Arg-Arg-Phe-Arg-Arg at the cleavage site of the spike precursor propolypeptide of IBV strains Beaudette and M41.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chick Embryo; Chickens; Cloning, Molecular; Coronaviridae; Electrophoresis, Polyacrylamide Gel; Infectious bronchitis virus; Isoleucine; Leucine; Protein Precursors; Serine; Valine; Viral Envelope Proteins; Viral Proteins | 1986 |
Isoleucyl-tRNA synthetase from baker's yeast. Influence of substrate concentrations on aminoacylation pathways, discrimination between tRNAIle and tRNAVal, and between isoleucine and valine.
Topics: Adenosine Monophosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Pyrophosphatases; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Substrate Specificity; Valine | 1986 |
Toxic accumulation of alpha-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium.
Topics: Acetolactate Synthase; Butyrates; DNA Transposable Elements; Isoleucine; Kinetics; Mutation; Oxo-Acid-Lyases; Salmonella typhimurium; Sulfonylurea Compounds; Valine | 1987 |
Translational coupling between the ilvD and ilvA genes of Escherichia coli.
Topics: DNA Mutational Analysis; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Isoleucine; Operon; Plasmids; Protein Biosynthesis; Restriction Mapping; RNA, Messenger; Valine | 1988 |
Towards diacetyl-less brewers' yeast. Influence of ilv2 and ilv5 mutations.
Topics: Acetolactate Synthase; Butanones; Chromosome Mapping; Diacetyl; Genes, Fungal; Isoleucine; Lactates; Mutation; Pentanones; Saccharomyces; Saccharomyces cerevisiae; Valine | 1988 |
Sequential metabolic characteristics following portacaval shunt in rats.
Topics: Amino Acids; Animals; Body Weight; Glucagon; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1986 |
Aminotransferase activities in Trichomonas vaginalis.
Topics: Alanine Transaminase; Amino Acids; Animals; Chromatography, Gel; Isoleucine; Leucine; Lysine; Ornithine; Spectrophotometry; Transaminases; Trichomonas vaginalis; Valine | 1986 |
Effect of enrichment of infusion solutions with branched chain amino acids in parenteral nutrition of rats.
Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Creatinine; Energy Intake; Isoleucine; Leucine; Liver; Male; Methylhistidines; Muscle Proteins; Muscles; Nutritional Status; Parenteral Nutrition, Total; Polyribosomes; Proteins; Rats; Rats, Inbred Strains; Valine | 1987 |
Utilization of the L- and DL-isomers of alpha-keto-beta-methylvaleric acid by rats and comparative efficacy of the keto analogs of branched-chain amino acids provided as ornithine, lysine and histidine salts.
Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Eating; Hemiterpenes; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Male; Ornithine; Rats; Rats, Inbred Strains; Salts; Stereoisomerism; Valine | 1987 |
Studies on the biosynthesis of beta-amino acids, the lipid moiety of iturins A, in Bacillus subtilis.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Carbon Radioisotopes; Isoleucine; Leucine; Palmitic Acid; Palmitic Acids; Peptides; Peptides, Cyclic; Valine | 1988 |
Characterization of a novel L-serine transport system in Escherichia coli.
Topics: Alanine; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Culture Media; Escherichia coli; Glycine; Isoleucine; Kinetics; Potassium Cyanide; Serine; Threonine; Valine | 1988 |
[Plasma level of branched-chain amino and keto acids in healthy subjects after an intravenous dose of MCT/LCT or LCT].
Topics: Adult; Amino Acids, Branched-Chain; Caproates; Fasting; Fat Emulsions, Intravenous; Female; Hemiterpenes; Humans; Infusions, Intravenous; Insulin; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Random Allocation; Triglycerides; Valerates; Valine | 1988 |
Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae.
Topics: Enzyme Repression; Gene Expression Regulation; Genes; Genes, Fungal; Isoleucine; RNA, Messenger; Saccharomyces cerevisiae; Threonine Dehydratase; Transcription, Genetic; Valine | 1988 |
Common evolutionary origin of the ilvGMEDA attenuation locus and tRNA(1Leu) in Escherichia coli.
Topics: Biological Evolution; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Isoleucine; Nucleic Acid Conformation; Operon; RNA, Messenger; RNA, Transfer, Amino Acyl; Sequence Homology, Nucleic Acid; Transcription, Genetic; Valine | 1987 |
Isoleucyl-tRNA synthetase from Escherichia coli MRE 600: discrimination between isoleucine and valine with modulated accuracy.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Saccharomyces cerevisiae; Substrate Specificity; Thermodynamics; Valine | 1987 |
Sex-specific differences in plasma branched-chain keto acid levels in obesity.
Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine | 1987 |
Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria.
Topics: Acetolactate Synthase; Butyrates; Escherichia coli; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoenzymes; Isoleucine; Kinetics; Lactates; Oxo-Acid-Lyases; Pyruvates; Pyruvic Acid; Salmonella typhimurium; Valine | 1987 |
NMR analyses of the conformations of L-isoleucine and L-valine bound to Escherichia coli isoleucyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Protein Binding; Valine | 1987 |
Effects of ornithine or arginine administration on serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Female; Humans; Insulin; Isoleucine; Leucine; Liver; Male; Middle Aged; Ornithine; Urea; Valine | 1987 |
Failure to detect beta-leucine in human blood or leucine 2,3-aminomutase in rat liver using capillary gas chromatography-mass spectrometry.
Topics: Adult; Amino Acid Isomerases; Amino Acids, Branched-Chain; Animals; Female; Gas Chromatography-Mass Spectrometry; Humans; Intramolecular Transferases; Isoleucine; Leucine; Liver; Male; Microchemistry; Middle Aged; Rats; Silicon; Valine; Vitamin B 12 Deficiency | 1988 |
pK shift of functional group in mechanochemical coupling due to hydrophobic effect: evidence for an apolar-polar repulsion free energy in water.
Topics: Elastin; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Magnetic Resonance Spectroscopy; Oligopeptides; Solubility; Structure-Activity Relationship; Temperature; Thermodynamics; Valine; Water | 1988 |
GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.
Topics: Binding Sites; Fungal Proteins; Histidine; Isoleucine; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Transcription Factors; Valine; Yeasts | 1986 |
Acetohydroxy acid synthase I, a required enzyme for isoleucine and valine biosynthesis in Escherichia coli K-12 during growth on acetate as the sole carbon source.
Topics: Acetates; Acetolactate Synthase; Carbon; Escherichia coli; Genes, Bacterial; Isoleucine; Mutation; Oleic Acid; Oleic Acids; Oxo-Acid-Lyases; Plasmids; Transformation, Genetic; Valine | 1986 |
Lipogenesis in isolated human sebaceous glands.
Topics: Carbon Radioisotopes; Glucose; Humans; Isoleucine; Leucine; Lipids; Radioisotope Dilution Technique; Sebaceous Glands; Valine | 1986 |
2-ketoglutarate generation in pancreatic B-cell mitochondria regulates insulin secretory action of amino acids and 2-keto acids.
Topics: Amino Acids; Animals; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Keto Acids; Ketoglutaric Acids; Mice; Mice, Obese; Mitochondria; Valine | 1986 |
Alcohol intake and withdrawal: effects on branched chain amino acids and alanine.
Topics: Adult; Alanine; Alcoholism; Amino Acids; Blood Glucose; Diet; Ethanol; Humans; Isoleucine; Leucine; Male; Middle Aged; Substance Withdrawal Syndrome; Valine | 1986 |
Acetohydroxy acid synthase I is required for isoleucine and valine biosynthesis by Salmonella typhimurium LT2 during growth on acetate or long-chain fatty acids.
Topics: Acetates; Acetolactate Synthase; Fatty Acids, Nonesterified; Genotype; Isoleucine; Oxo-Acid-Lyases; Salmonella typhimurium; Valine | 1987 |
Effect of the deletion of upstream DNA sequences on expression from the ilvGp2 promoter of the ilvGMEDA operon of Escherichia coli K-12.
Topics: Base Sequence; Chromosome Deletion; DNA, Bacterial; Escherichia coli; Genes; Genes, Regulator; Isoleucine; Operon; Plasmids; Promoter Regions, Genetic; Transcription, Genetic; Valine | 1987 |
The complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli K-12.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Genes; Genes, Bacterial; Isoleucine; Nucleic Acid Conformation; Operon; Transcription, Genetic; Valine | 1987 |
[Metabolic study of the classic form of leucinosis during exchange transfusion therapy].
Topics: Exchange Transfusion, Whole Blood; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1987 |
Comparison between acute and chronic effects of ammonia on branched-chain amino acid oxidation and incorporation into protein in primary cultures of astrocytes and of neurons.
Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Astrocytes; Brain; Cells, Cultured; Glutamine; Isoleucine; Leucine; Mice; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Valine | 1987 |
Twenty-four-hour variations in rat blood and brain levels of the aromatic and branched-chain amino acids: chronic effects of dietary protein content.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Brain; Circadian Rhythm; Dietary Proteins; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1987 |
Acute effect of ammonia on branched-chain amino acid oxidation and incorporation into proteins in astrocytes and in neurons in primary cultures.
Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Astrocytes; Cell Differentiation; Cells, Cultured; Isoleucine; Leucine; Mice; Neurons; Oxidation-Reduction; Proteins; Time Factors; Valine | 1987 |
Hemoglobin Hamilton [beta 11(A8)Val----Ile] in Sardinia.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Genetic Testing; Hemoglobins, Abnormal; Heterozygote; Humans; Infant, Newborn; Isoleucine; Italy; Peptide Mapping; Valine | 1987 |
Leucine and isoleucine activate skeletal muscle branched-chain alpha-keto acid dehydrogenase in vivo.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Enzyme Activation; Isoleucine; Ketone Oxidoreductases; Kinetics; Leucine; Magnesium; Male; Multienzyme Complexes; Muscles; Rats; Rats, Inbred Strains; Valine | 1986 |
No significant net uptake of branched chain amino acids by the liver of fed-mid pregnant rats.
Topics: Amino Acids, Branched-Chain; Animals; Biological Transport; Female; Isoleucine; Kinetics; Leucine; Liver; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Valine | 1986 |
[The plasma molar ratio of valine, leucine and isoleucine to phenylalanine and tyrosine as a marker of portal-systemic shunt in liver cirrhosis].
Topics: Adult; Collateral Circulation; Female; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Portal System; Portography; Tyrosine; Valine | 1986 |
Amino acid catabolism in the nematodes Heligmosomoides polygyrus and Panagrellus redivivus. 2. Metabolism of the carbon skeleton.
Topics: Amino Acids; Animals; Heligmosomatoidea; Isoleucine; Leucine; Liver; Nematoda; Nematospiroides dubius; Proline; Rats; Valine | 1986 |
[Leucinosis: study of a case].
Topics: Female; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Valine | 1985 |
Acylamino boronic acids and difluoroborane analogues of amino acids: potent inhibitors of chymotrypsin and elastase.
Topics: Acylation; Alanine; Amino Acids; Binding, Competitive; Boranes; Boronic Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Glycine; Hydrolysis; Isoleucine; Pancreatic Elastase; Phenylalanine; Structure-Activity Relationship; Valine | 1985 |
The effect of branch chain amino acids on the proliferation of normal and uremic cells.
Topics: Cell Division; Cells, Cultured; Humans; Isoleucine; Kidney Failure, Chronic; Leucine; Lymphocytes; Renal Dialysis; Uremia; Valine | 1985 |
Unusual organization of the ilvIH promoter of Escherichia coli.
Topics: Base Sequence; Chromosome Deletion; Chromosome Mapping; DNA, Bacterial; Escherichia coli; Gene Expression Regulation; Isoleucine; Leucine; Molecular Sequence Data; Mutation; Operon; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Valine | 1985 |
Branched-chain amino acid aminotransferase of Escherichia coli: nucleotide sequence of the ilvE gene and the deduced amino acid sequence.
Topics: Amino Acid Sequence; Aspartate Aminotransferases; Base Sequence; Cloning, Molecular; Escherichia coli; Genes; Genes, Bacterial; Isoleucine; Protein Conformation; Transaminases; Valine | 1985 |
Comparison of the regulatory regions of ilvGEDA operons from several enteric organisms.
Topics: Base Sequence; Codon; Enterobacteriaceae; Escherichia coli; Genes, Regulator; Isoleucine; Leucine; Operon; Plasmids; Serratia marcescens; Transcription, Genetic; Valine | 1985 |
Leucine regulation of the ilvGEDA operon of Serratia marcescens by attenuation is modulated by a single leucine codon.
Topics: Codon; Escherichia coli; Isoleucine; Leucine; Operon; Plasmids; RNA, Messenger; RNA, Transfer, Amino Acyl; Serratia marcescens; Transaminases; Valine | 1985 |
Control of isoleucine-valine biosynthesis in a valine-resistant mutant of Escherichia coli K-12 that simultaneously acquired azaleucine-resistance.
Topics: Acetolactate Synthase; Amino Acyl-tRNA Synthetases; Escherichia coli; Hydro-Lyases; Isoleucine; Leucine; Mutation; Threonine Dehydratase; Transduction, Genetic; Valine | 1985 |
Metabolism of branched-chain amino acids in rats with acute hepatic failure: a tracer study using 15N-leucine.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Glucagon; Glutamine; Insulin; Isoleucine; Leucine; Liver Diseases; Male; Rats; Rats, Inbred Strains; Valine | 1985 |
Solubilization and reconstitution of sodium-dependent transport system for branched-chain amino acids from Pseudomonas aeruginosa.
Topics: Amino Acids, Branched-Chain; Biological Transport; Isoleucine; Kinetics; Leucine; Liposomes; Pseudomonas aeruginosa; Sodium; Solubility; Valine | 1985 |
beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase.
Topics: Alanine; beta-Alanine; Escherichia coli; Isoleucine; Transaminases; Valine | 1985 |
Immobilization decreases amino acid concentrations in plasma but maintains or increases them in brain.
Topics: Amino Acids; Animals; Brain Chemistry; Humans; Immobilization; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1986 |
Kinetics of inhibition of rat liver and kidney arginases by proline and branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Animals; Arginase; Isoleucine; Kidney; Kinetics; Leucine; Liver; Proline; Rats; Valine | 1986 |
Biosynthesis of monensins A and B: the role of isoleucine.
Topics: Aminobutyrates; Butyrates; Furans; Isoleucine; Monensin; Mutation; Norleucine; Streptomyces; Valine | 1986 |
Isoleucine and valine oxidation following skeletal trauma in rats.
Topics: Animals; Femoral Fractures; Fractures, Bone; Hematoma; Humans; Isoleucine; Male; Nitrogen; Oxidation-Reduction; Rats; Rats, Inbred Strains; Time Factors; Valine | 1986 |
Suppression of granulopoietic progenitor cell proliferation by metabolites of the branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Cells, Cultured; Colony-Forming Units Assay; Depression, Chemical; Granulocytes; Hematopoietic Stem Cells; Humans; Isoleucine; Leucine; Malonates; Propionates; Valine | 1985 |
Preliminary support for the oral administration of valine, isoleucine and leucine for phenylketonuria.
Topics: Adolescent; Adult; Child; Cognition; Drug Therapy, Combination; Electroencephalography; Humans; Isoleucine; Learning; Leucine; Neuropsychological Tests; Phenylketonurias; Psychomotor Performance; Valine | 1985 |
The different effects of leucine, isoleucine, and valine on systolic properties of the normal and septic isolated rat heart.
Topics: Amino Acids, Branched-Chain; Animals; Coronary Circulation; In Vitro Techniques; Infections; Isoleucine; Leucine; Myocardial Contraction; Perfusion; Rats; Systole; Valine | 1985 |
Properties of a microsomal enzyme system from Linum usitatissimum (linen flax) which oxidizes valine to acetone cyanohydrin and isoleucine to 2-methylbutanone cyanohydrin.
Topics: Chromatography, Gas; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Microsomes; Nitriles; Oxidation-Reduction; Plants; Substrate Specificity; Valine | 1985 |
Active transport of nonpolar amino acids in Chromatium vinosum.
Topics: Alanine; Amino Acids; Binding, Competitive; Biological Transport, Active; Chromatium; Darkness; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Light; Phenylalanine; Sodium; Valine | 1985 |
Enhancement of bacitracin biosynthesis by branched-chain amino acids in a regulatory mutant of Bacillus licheniformis.
Topics: Amino Acids, Branched-Chain; Bacillus; Bacitracin; Genes, Bacterial; Genes, Regulator; Isoleucine; Leucine; Mutation; Transaminases; Valine | 1985 |
Modulation of branched-chain amino acid oxidation in rat hemidiaphragms in vitro by glucose and ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids, Branched-Chain; Animals; Carbon Radioisotopes; Diaphragm; Glucose; Hydroxybutyrates; Isoleucine; Kinetics; Leucine; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Valine | 1985 |
Pharmacokinetic and metabolic interrelationships among branched-chain keto and amino acids in humans.
Topics: Adult; Amino Acids, Branched-Chain; Drug Interactions; Female; Half-Life; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Reference Values; Time Factors; Valine | 1985 |
Relationship between food consumption and energy and nitrogen utilisation by chicks given varying amounts of standard and leucine-, isoleucine- and valine-deficient diets.
Topics: Amino Acids, Essential; Animals; Chickens; Diet; Eating; Energy Metabolism; Isoleucine; Leucine; Male; Nitrogen; Valine | 1985 |
Corticosteroid induced changes in plasma amino acids and thyroid activity in dairy cows treated early or late during lactation.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Body Weight; Cattle; Dexamethasone; Female; Flumethasone; Glutamine; Glycerol; Iodine; Isoleucine; Lactation; Methionine; Phenylalanine; Pregnancy; Serine; Thyroid Function Tests; Thyroid Gland; Tyrosine; Urea; Valine | 1971 |
[Biosynthetic actinomycins from aurantin-producing Actynomyces].
Topics: Actinomyces; Amino Acids; Antibiotics, Antineoplastic; Chromatography; Culture Media; Dactinomycin; Flavonoids; Isoleucine; Leucine; Oxidation-Reduction; Proline; Sarcosine; Threonine; Valine | 1971 |
Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibody Formation; Antigens; Aspartic Acid; Binding Sites; Carbon Isotopes; Clostridium; Complement Fixation Tests; Complement System Proteins; Dialysis; Electrophoresis; Epitopes; Ferredoxins; Formates; Glutamates; Glutamine; Haptens; Immune Sera; Immunoglobulin G; Isoleucine; Lysine; Oxidation-Reduction; Peptides; Proline; Rabbits; Serine; Tyrosine; Valine | 1971 |
[Toxicity and cumulative properties of actinomycins C1, C2 and C3, contained in preparations in various combinations].
Topics: Animals; Body Weight; Cats; Dactinomycin; Depression, Chemical; Diarrhea; Feeding and Eating Disorders; Hemoglobins; Humans; Injections, Intraperitoneal; Injections, Intravenous; Isoleucine; Male; Mice; Neoplasms, Experimental; Stomatitis; Valine; Vomiting | 1971 |
[Properties of amino acid pools of actinomycin-producing actinomycetes].
Topics: Actinomycetales; Alanine; Amino Acids; Chloramphenicol; Culture Media; Dactinomycin; Glycine; Isoleucine; Leucine; Peptides; Phenylalanine; Threonine; Thyroxine; Valine | 1973 |
[Production of actinomycin by Actinomyces michiganensis strain 538].
Topics: Actinomyces; Culture Media; Dactinomycin; Isoleucine; Proline; Valine | 1973 |
Pleiotropic effects resulting from mutations in genes for ribosomal proteins: analysis of revertants from streptomycin dependence.
Topics: Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; Chromatography; Dihydrostreptomycin Sulfate; Drug Resistance, Microbial; Escherichia coli; Genes; Isoleucine; Mutation; Peptide Biosynthesis; Phenotype; Protein Biosynthesis; Ribosomes; Streptomycin; Tritium; Uracil; Valine | 1974 |
[Isoleucine biosynthesis in mutants for arthrobacter following varying growth conditions].
Topics: Alcohol Oxidoreductases; Allosteric Regulation; Arthrobacter; Enzyme Induction; Enzyme Repression; Feedback; Glucose; Homoserine; Hydro-Lyases; Hydrogen-Ion Concentration; Iron; Isoleucine; Leucine; Ligases; Models, Biological; Mutation; Oxo-Acid-Lyases; Pyruvates; Threonine; Valine | 1972 |
Cutaneous lipogenesis. Major pathways of carbon flow and possible interrelationships between the epidermis and sebaceous glands.
Topics: Acetates; Acids; Alanine; Amino Acids; Animals; Aspartic Acid; Butyrates; Carbon Dioxide; Carbon Radioisotopes; Citrates; Coenzyme A; Glucose; Glutamates; Glycine; Guinea Pigs; Isoleucine; Lactates; Leucine; Lipids; Lysine; Methionine; NADH, NADPH Oxidoreductases; Phenylalanine; Propionates; Pyruvates; Sebaceous Glands; Skin; Succinates; Valine | 1974 |
Radiochemical determination of the optical purity of L-amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Catalase; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Selenium; Serine; Stereoisomerism; Tritium; Tyrosine; Valine | 1974 |
D- and L-isoleucine metabolism and regulation of their pathways in Pseudomonas putida.
Topics: Alcohol Oxidoreductases; Cell-Free System; Chromatography, DEAE-Cellulose; Coenzyme A; Crotonates; Culture Media; D-Amino-Acid Oxidase; Electrophoresis, Disc; Enzyme Induction; Glucose; Glutamates; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoleucine; Leucine; Oxo-Acid-Lyases; Pseudomonas; Spectrophotometry; Stereoisomerism; Succinates; Transaminases; Valine | 1974 |
Regulation of leucine catabolism in Pseudomonas putida.
Topics: Alcohol Oxidoreductases; Cell-Free System; Chromatography, Paper; D-Amino-Acid Oxidase; Enzyme Induction; Enzyme Repression; Glucose; Glutamates; Isoleucine; Ketones; Leucine; Ligases; Mutation; Oxidation-Reduction; Oxo-Acid-Lyases; Pseudomonas; Spectrophotometry; Stereoisomerism; Succinates; Transaminases; Valerates; Valine | 1974 |
Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons.
Topics: Acids; Amino Acids; Depression, Chemical; Enzyme Repression; Histidine; Hydro-Lyases; Isoleucine; Leucine; NADH, NADPH Oxidoreductases; Operon; Oxo-Acid-Lyases; Peptides; Phenotype; RNA, Transfer; Salmonella typhimurium; Threonine; Uridine; Valine | 1974 |
Biosynthesis of branched long-chain fatty acids by species of Bacillus: relative activity of three alpha-keto acid substrates and factors affecting chain length.
Topics: Bacillus cereus; Bacillus subtilis; Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; Coenzyme A; Dithiothreitol; Escherichia coli; Fatty Acid Synthases; Fatty Acids; Hot Temperature; Isoleucine; Keto Acids; Leucine; NADP; Valine | 1974 |
Metabolic precursors of methylmalonic acid in vitamin-B12 deficiency.
Topics: Humans; Isoleucine; Malonates; Propionates; Valine; Vitamin B 12 Deficiency | 1967 |
Gas-liquid chromatography of derivatives of several amino acids that occur in the actinomycins.
Topics: Amino Acids; Boron Compounds; Chromatography, Gas; Dactinomycin; Furans; Hydrochloric Acid; Hydroxyproline; Isoleucine; Proline; Sarcosine; Threonine; Valine | 1967 |
[Comparison of the isoleyl- and leucyl-tRNA synthetases of "Bacillus stearothermophilus" and "Escherichia coli". 1. Properties of the enzymes].
Topics: Bacillus; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromatography, Ion Exchange; Escherichia coli; Hot Temperature; Isoleucine; Leucine; Ligases; Protein Denaturation; RNA, Bacterial; RNA, Transfer; Species Specificity; Valine | 1968 |
[Preparative biosynthesis of C14-actinomycines].
Topics: Amino Acids; Antibiotics, Antineoplastic; Carbon Isotopes; Dactinomycin; Flavonoids; Glycine; Isoleucine; Proline; Threonine; Valine | 1968 |
Plasma-aminoacid levels in Huntington's chorea.
Topics: Adult; Alanine; Amino Acids; Female; Humans; Huntington Disease; Isoleucine; Leucine; Male; Middle Aged; Proline; Schizophrenia; Tyrosine; Valine | 1969 |
Stimulation of insulin secretion in vitro by essential aminoacids.
Topics: Animals; Arginine; Dogs; Glucose; Histidine; In Vitro Techniques; Insulin; Insulin Secretion; Isoleucine; Leucine; Lysine; Methionine; Pancreas; Phenylalanine; Rabbits; Rats; Stimulation, Chemical; Threonine; Tryptophan; Valine | 1969 |
Plasma and red blood cell amino acids of Egyptian children suffering from protein--calorie malnutrition.
Topics: Alanine; Amino Acids; Child, Preschool; Chromatography, Paper; Diet Therapy; Egypt; Erythrocytes; Follow-Up Studies; Glutamine; Glycine; Humans; Infant; Infant Nutrition Disorders; Isoleucine; Kwashiorkor; Leucine; Methionine; Protein-Energy Malnutrition; Serine; Valine | 1973 |
Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes.
Topics: Bacterial Proteins; Dactinomycin; Edetic Acid; Enzyme Repression; Escherichia coli; Half-Life; Hydro-Lyases; Hydroxylamines; Isoleucine; Kinetics; Leucine; Mutation; Protein Biosynthesis; Rifampin; RNA, Bacterial; RNA, Messenger; Salmonella typhimurium; Threonine; Time Factors; Valine | 1973 |
Biosynthesis of the fifth component of complement (C5) by human fetal tissues.
Topics: Carbon Radioisotopes; Complement System Proteins; Culture Techniques; Cycloheximide; Fetus; Gestational Age; Hemolysis; Humans; Immunodiffusion; Intestine, Small; Isoleucine; Leucine; Liver; Lysine; Valine | 1973 |
Acetolactate synthase of Pseudomonas aeruginosa I. Purification and allosteric properties.
Topics: Allosteric Regulation; Chromatography, Gel; Feedback; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Magnesium; Oxo-Acid-Lyases; Polyethylene Glycols; Pseudomonas aeruginosa; Pyruvates; Temperature; Thiamine Pyrophosphate; Ultracentrifugation; Valine | 1973 |
L-amino acid dehydrogenases in Bacillus subtilis spores.
Topics: Alanine; Amino Acid Oxidoreductases; Ammonium Sulfate; Bacillus subtilis; Cell-Free System; Chemical Precipitation; Chromatography; Chromatography, Gel; Deamination; Electrolysis; Hydrogen-Ion Concentration; Isoleucine; Leucine; Molecular Weight; Spectrophotometry; Spores, Bacterial; Stereoisomerism; Valine | 1974 |
Phenotypic derepression of enzymes of the isoleucine-valine pathway by isoleucine in Pseudomonas aeruginosa.
Topics: Cell-Free System; Chromatography, Gel; Enzyme Repression; Genetic Variation; Hydro-Lyases; Isoleucine; Leucine; Lyases; Methionine; Mutation; Phenotype; Pseudomonas aeruginosa; Pyruvates; Threonine; Transaminases; Uracil; Valine | 1972 |
L-threonine deaminase in marine planktonic algae. IV. Studies of substrate specificity and inhibition from substrate analogs. Evidence for additional L-serine deaminase activity in the cryptophyte Chroomonas salina.
Topics: Ammonium Chloride; Deamination; Dithiothreitol; Edetic Acid; Eukaryota; Homoserine; Hydro-Lyases; Isoleucine; L-Serine Dehydratase; Phytoplankton; Plankton; Plant Extracts; Potassium Chloride; Serine; Species Specificity; Stereoisomerism; Threonine; Valine; Water Microbiology | 1973 |
Strains of Bacillus subtilis synthesizing elevated levels of isoleucine-valine biosynthetic enzymes.
Topics: Amino Acyl-tRNA Synthetases; Bacillus subtilis; Chromosome Mapping; Enzyme Repression; Genes, Regulator; Genetic Linkage; Hydro-Lyases; Isoleucine; Mutation; Selection, Genetic; Transaminases; Valine | 1974 |
Methylmalonic acid excretion studies.
Topics: Administration, Oral; Anemia, Pernicious; Biological Assay; Chromatography, Gas; Erythrocyte Count; Folic Acid Deficiency; Humans; Isoleucine; Lacticaseibacillus casei; Lactobacillus; Leucine; Liver Cirrhosis; Malonates; Methionine; Stimulation, Chemical; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
[Transfer of fatty acids and proteins between cytoplasmic membranes and mesosomes of Bacillus subtilis var. niger].
Topics: Bacillus subtilis; Bacterial Proteins; Biological Transport; Carbon Radioisotopes; Cell Membrane; Fatty Acids; Isoleucine; Kinetics; Organoids; Protein Biosynthesis; Protoplasts; Time Factors; Valine | 1974 |
Measurement of intracellular amino acids in cultured skin fibroblasts. The effect of storage on cystine recovery and evaluation of three methods of cell preparation.
Topics: Alanine; Amino Acids; Cells, Cultured; Cysteine; Cystinosis; Edetic Acid; Female; Fibroblasts; Freezing; Glutamates; Glycine; Heterozygote; Humans; Isoleucine; Leucine; Male; Methods; Skin; Temperature; Trypsin; Valine | 1974 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
[Hepatic steatosis and cholesterolemia in the domestic duckling in the course of protein malnutrition on a rice diet].
Topics: Animals; Arginine; Deficiency Diseases; Fatty Liver; Glutamine; Glycine; Growth; Histidine; Hypercholesterolemia; Isoleucine; Leucine; Lysine; Methionine; Oryza; Phenylalanine; Poultry Diseases; Protein Deficiency; Threonine; Tryptophan; Valine | 1965 |
[On an oviduct acellular system in laying chickens].
Topics: Amino Acids; Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chickens; Female; In Vitro Techniques; Isoleucine; Leucine; Lysine; Oviducts; Ovulation; Phenylalanine; Protein Biosynthesis; Serine; Valine | 1968 |
Biochemistry of Pasteurella pestis. II. Metabolism of some amino acids.
Topics: Alanine; Amino Acids; Carbon Isotopes; Glutamates; Glycine; Isoleucine; Leucine; Phenylalanine; Stereoisomerism; Valine; Yersinia pestis | 1964 |
Fragmentation of haptoglobin by plasmin.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis; Fibrinolysin; Haptoglobins; Hemoglobins; Humans; Isoleucine; Molecular Weight; Peptides; Polymers; Protein Binding; Serine; Ultracentrifugation; Valine | 1971 |
Effect of trimethoprim on macromolecular synthesis in Escherichia coli.
Topics: Adenine; Bacterial Proteins; Carbon Isotopes; DNA, Bacterial; Escherichia coli; Floxuridine; Folic Acid Antagonists; Isoleucine; Ligases; Nucleotides; Purines; Pyrimidines; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Thymidine; Tritium; Uracil; Valine | 1971 |
Biosynthesis of isoleucine & valine in Mycobacterium tuberculosis H 37 Rv. 3. Purification & properties of acetohydroxy acid isomeroreductase.
Topics: Alcohol Oxidoreductases; Isoleucine; Mycobacterium tuberculosis; Valine | 1971 |
Separation of mitochondrial membranes of Neurospora crassa. II. Submitochondrial localization of the isoleucine-valine biosynthetic pathway.
Topics: Alcohol Oxidoreductases; Centrifugation, Density Gradient; Cytochromes; Digitalis Glycosides; Hydro-Lyases; Isoleucine; Kynurenine; Lyases; Malate Dehydrogenase; Membranes; Mitochondria; Mixed Function Oxygenases; Neurospora; Neurospora crassa; Oxidoreductases; Saponins; Spirostans; Succinates; Transaminases; Valine | 1972 |
Genetic determination of high meiotic reversion frequencies in isoleucine-valine 1 homoallelic crosses in Neurospora.
Topics: Alleles; Chromosome Mapping; Crosses, Genetic; Crossing Over, Genetic; Genotype; Heterozygote; Homozygote; Isoleucine; Meiosis; Mutation; Neurospora crassa; Spores, Fungal; Valine | 1972 |
Altered species of mitochondrial transfer RNA associated with the mi-1 cytoplasmic mutation in Neurospora crassa.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Carbon Isotopes; Chromatography, DEAE-Cellulose; Cytoplasm; Glycine; Isoleucine; Leucine; Mitochondria; Mutation; Neurospora; Neurospora crassa; Phenylalanine; RNA, Transfer; Tritium; Valine | 1972 |
Control of acetohydroxy acid synthetase in Neurospora crassa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Mitochondria; Mixed Function Oxygenases; Neurospora; Neurospora crassa; Oxo-Acid-Lyases; Pyruvates; Valine | 1972 |
Branded chain amino acid aminotransferases of Neurospora crassa.
Topics: Amino Acids; Ammonium Sulfate; Biological Assay; Buffers; Chromatography, DEAE-Cellulose; Chromatography, Gel; Culture Media; Cytosol; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Phenylalanine; Protamines; Sulfhydryl Reagents; Transaminases; Valine; Vibration | 1973 |
Selective inhibition of initiating ribosomes by spectinomycin.
Topics: Bacterial Proteins; Carbon Radioisotopes; Escherichia coli; In Vitro Techniques; Isoleucine; Methionine; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polyribosomes; Puromycin; Rifampin; RNA, Bacterial; RNA, Messenger; RNA, Transfer; RNA, Viral; Spectinomycin; Tritium; Valine | 1974 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; Magnesium; Methionine; Niacinamide; Obstetric Labor Complications; Phenylalanine; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Rheumatic Heart Disease; Sodium; Tryptophan; Tyrosine; Valine; Vitamin E | 1974 |
Growth, respiratory, and cytochrome characteristics of certain of the isoleucine-valine mutants of Neurospora crassa.
Topics: Cell Division; Centrifugation, Density Gradient; Chromosome Mapping; Cyanides; Cytochromes; Dithionite; Ferricyanides; Isoleucine; Lysergic Acid Diethylamide; Mitochondria; Mutation; Neurospora; Neurospora crassa; Oxidation-Reduction; Oxygen Consumption; Species Specificity; Spectrophotometry; Time Factors; Valine | 1974 |
A pyruvate-valine enzyme complex that is dependent upon the metabolic state of the mitochondria.
Topics: Carbon Radioisotopes; Hydro-Lyases; Isoleucine; Isomerases; Mitochondria; Molecular Weight; Multienzyme Complexes; Neurospora; Neurospora crassa; Oxo-Acid-Lyases; Transaminases; Valine | 1974 |
Virus-specific proteins produced in HeLa cells infected with poliovirus: characterization of subunit-like protein.
Topics: Antigens; Chromatography; Culture Techniques; HeLa Cells; Isoleucine; Leucine; Poliovirus; Precipitin Tests; Ultracentrifugation; Valine; Viral Proteins; Virus Cultivation | 1965 |
[Separation and properties of leucine dehydrogenase and alanine dehydrogenase of Bacillus subtilis].
Topics: Alanine; Amino Acid Oxidoreductases; Aminobutyrates; Bacillus subtilis; Chromatography; Electrophoresis; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Kinetics; Leucine; NAD; Valine | 1965 |
Micromethod for the quantitative determination of L-alanine.
Topics: Alanine; Aminobutyrates; Cysteine; Isoleucine; Kinetics; Microchemistry; NAD; Serine; Spectrum Analysis; Valine | 1965 |
Possible "allosteric" effects controlling the kinetic behavior of amino acid-dependent pyrophosphate exchange reactions.
Topics: Adenosine Triphosphate; Animals; Chemistry Techniques, Analytical; Diphosphates; In Vitro Techniques; Isoleucine; Kinetics; Leucine; Liver; Lysine; Rats; RNA, Transfer; Saccharomyces; Valine | 1966 |
[Selectivity of the antagonism of some methylated substances on the antipoliomyelitic effect in vitro of guanidine].
Topics: Culture Techniques; Dimethyl Sulfoxide; Dimethylformamide; Drug Antagonism; Ethionine; Guanidines; Isoleucine; Methanol; Methionine; Poliovirus; Valine | 1966 |
The specificity of enzymic reactions. Aminoacyl-soluble RNA ligases.
Topics: Adenosine Triphosphate; Carbon Isotopes; Diphosphates; Escherichia coli; Isoleucine; Kinetics; Ligases; Models, Theoretical; Phosphorus Isotopes; RNA, Bacterial; RNA, Transfer; Valine | 1966 |
Photochemistry of biological molecules. I. Photolysis of amino acids in the solid state.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Crystallization; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Isoleucine; Radiation; Radiation Effects; Ultraviolet Rays; Valerates; Valine | 1967 |
O-methylthreonine inhibition of growth and of threonine deaminase in Escherichia coli.
Topics: Adenosine Triphosphate; Aminohydrolases; Diphosphates; Enzyme Repression; Escherichia coli; Isoleucine; Leucine; Mercury; Phosphorus Isotopes; RNA, Transfer; Threonine; Tritium; Valine | 1967 |
Isoleucine and valine metabolism of Escherichia coli. XV. Biochemical properties of mutants resistant to thiaisoleucine.
Topics: Carbon Isotopes; Chromatography; Drug Resistance, Microbial; Escherichia coli; Hydro-Lyases; Isoleucine; Ligases; Mutation; Periodic Acid; RNA, Transfer; Transaminases; Valine | 1968 |
Primary structure of insoluble tendon collagen. I. N- and C-terminal positional analysis of collagenolytic breakdown products of native collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Methods; Microbial Collagenase; Phenylalanine; Proline; Valine | 1968 |
Mechanism of action of amino acid transfer ribonucleic acid ligases.
Topics: Adenosine Triphosphate; Amino Acids; Anhydrides; Bacterial Proteins; Carbon Isotopes; Chemical Phenomena; Chemistry; Diphosphates; Escherichia coli; Hydroxamic Acids; Hydroxylamines; Isoleucine; Kinetics; Ligases; Models, Biological; Phosphorus Isotopes; RNA, Transfer; Valine | 1969 |
Amino acid analysis after degradation of angiotensinII by rat kidney lysosomes.
Topics: Amino Acids; Angiotensin II; Animals; Autoanalysis; Histidine; In Vitro Techniques; Isoleucine; Kidney; Lysosomes; Phenylalanine; Proline; Rats; Valine | 1969 |
Primary gene products of an arbovirus.
Topics: Animals; Carbon Isotopes; Chickens; Culture Techniques; Dactinomycin; Electrophoresis; Genetics, Microbial; Isoleucine; Leucine; Poliovirus; Semliki forest virus; Time Factors; Tritium; Valine; Viral Proteins | 1969 |
Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures.
Topics: Amino Acids; Animals; Deficiency Diseases; Diet; Dietary Proteins; Feces; Female; Fetal Death; Fetus; Isoleucine; Kidney; Leucine; Liver; Male; Maternal-Fetal Exchange; NAD; Niacinamide; Nicotinic Acids; Nitrogen; Pregnancy; Pregnancy, Animal; Rats; Tryptophan; Valine | 1970 |
Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys.
Topics: Alanine; Amino Acids; Aminobutyrates; Amygdala; Animals; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Carbon Isotopes; Caudate Nucleus; Central Nervous System; Cerebral Cortex; Glutamates; Glycine; Haplorhini; Hypothalamus; Isoleucine; Methods; Perfusion; Phenylalanine; Proline; Synaptic Transmission; Technology, Radiologic; Tyrosine; Valine | 1970 |
[Dietetics in hereditary enzyme deficiencies].
Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Metabolism, Inborn Errors; Diarrhea, Infantile; Diet Therapy; Galactosemias; Homocystinuria; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1970 |
Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoproteins.
Topics: Animals; Carbon Isotopes; Carcinoma; Cell Line; Cell Membrane; Cytopathogenic Effect, Viral; Electrophoresis, Disc; Glucosamine; Glycoproteins; Haplorhini; Humans; Isoleucine; Kidney; Laryngeal Neoplasms; Leucine; Simplexvirus; Tritium; Valine; Viral Proteins | 1970 |
Proteins spcified by herpes simplex virus. II. Viral glycoprotins associated with cellular membranes.
Topics: Acrylates; Carbon Isotopes; Carcinoma; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Culture Techniques; Electrophoresis; Gels; Glucosamine; Glycoproteins; Humans; Isoleucine; Laryngeal Neoplasms; Leucine; Microscopy, Electron; Molecular Weight; Simplexvirus; Sucrose; Tritium; Valine; Viral Proteins | 1970 |
The pyruvate dehydrogenase complex from the mitochondrial fraction of Neurospora crassa.
Topics: Acetaldehyde; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Citrates; Coenzyme A; Isoleucine; Keto Acids; Kinetics; Microscopy, Electron; Mitochondria; Mutation; NAD; Neurospora; Oxidoreductases; Phosphates; Pyruvates; Sulfhydryl Compounds; Thiamine; Ultracentrifugation; Valerates; Valine | 1970 |
Specificity of the valyl ribonucleic acid synthetase from Escherichia coli in the binding of valine analogues.
Topics: Adenosine Triphosphate; Alanine; Amides; Amines; Amino Acids; Amino Alcohols; Aminobutyrates; Chemical Phenomena; Chemistry; Diphosphates; Escherichia coli; Esters; Glycine; Isoleucine; Kinetics; Leucine; Ligases; Peptides; Phosphorus Isotopes; Protein Binding; RNA, Transfer; Stereoisomerism; Threonine; Valine | 1970 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Transaminase of branched chain amino acids. VII. Comparative studies on isozymes of ascites hepatoma and various normal tissues of rat.
Topics: Adipose Tissue; Animals; Brain; Carcinoma, Hepatocellular; Chromatography; Chromatography, DEAE-Cellulose; Immunodiffusion; Isoenzymes; Isoleucine; Kidney; Leucine; Liver; Liver Neoplasms; Male; Molecular Weight; Muscles; Neoplasms, Experimental; Rats; Sarcoma, Yoshida; Spleen; Swine; Testis; Transaminases; Ultracentrifugation; Valine | 1970 |
[Dietetics of amino acid metabolism disorders].
Topics: Amino Acid Metabolism, Inborn Errors; Diet Therapy; Glycine; Histidine; Homocystinuria; Humans; Isoleucine; Leucine; Phenylketonurias; Tryptophan; Tyrosine; Valine | 1971 |
Isoleucyl-tRNA synthetase. A fluorescence study of the binding properties of the synthetase from Escherichia coli.
Topics: Adenosine Triphosphate; Chemical Phenomena; Chemistry, Physical; Diphosphates; Escherichia coli; Fluorescence; Glutathione; Isoleucine; Kinetics; Leucine; Ligases; Magnesium; RNA, Transfer; Sodium Chloride; Spectrophotometry; Temperature; Urea; Valine | 1971 |
Replacement of Mg 2+ by monovalent cations in aminoacyl transfer RNA formation.
Topics: Acetates; Adenosine Triphosphate; Ammonium Chloride; Aspartic Acid; Chlorides; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Paper; Dialysis; Diphosphates; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Hydroxamic Acids; Hydroxyapatites; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lithium; Lysine; Magnesium; Methionine; Phenylalanine; Phosphorus Isotopes; Potassium Chloride; RNA, Transfer; Sodium Chloride; Tryptophan; Tyrosine; Valine | 1971 |
Biochemical characterization of a mutant isoleucyl-transfer ribonucleic acid synthetase from Escherichia coli K-12.
Topics: Adenosine Triphosphate; Carbon Isotopes; Culture Media; Diphosphates; Escherichia coli; Genes; Genetics, Microbial; Hot Temperature; Isoleucine; Ligases; Mutation; Phosphorus Isotopes; RNA, Transfer; Time Factors; Valine | 1971 |
Crystalline L-leucine dehydrogenase.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Aminocaproates; Ammonium Sulfate; Bacillus; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Crystallization; Electrophoresis, Disc; Glutamates; Hydroxyapatites; Isoleucine; Leucine; Molecular Weight; NAD; Stereoisomerism; Ultracentrifugation; Valerates; Valine | 1971 |
Inactivation studies of angiotensin II by purified enzymes.
Topics: Amino Acids; Aminopeptidases; Angiotensin II; Animals; Arginine; Aspartic Acid; Brain; Isoleucine; Naphthalenes; Peptide Hydrolases; Swine; Tyrosine; Valine | 1971 |
The kinetics of radical decay in crystalline amino acids.
Topics: Alanine; Amino Acids; Crystallization; Electron Spin Resonance Spectroscopy; Free Radicals; Isoleucine; Kinetics; Leucine; Radiation Effects; Radiochemistry; Valine | 1972 |
Leucyl-tRNA synthetase. Two forms of the enzyme: role of sulfhydryl groups.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, Gel; Diphosphates; Escherichia coli; Isoleucine; Leucine; Maleimides; Methionine; Molecular Weight; RNA, Bacterial; RNA, Transfer; Sulfhydryl Compounds; Valine | 1971 |
Studies on transfer RNAs. I. A novel method for selective deamination of cytosine in oligonucleotides and transfer RNA.
Topics: Carbon Isotopes; Chromates; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Cryptococcus; Cytidine; Cytosine Nucleotides; Deamination; Electrophoresis, Paper; Hydrogen-Ion Concentration; Hydroxylamines; Isoleucine; Kinetics; Methionine; Oxidation-Reduction; Periodic Acid; Polynucleotides; RNA, Transfer; Spectrophotometry; Temperature; Ultraviolet Rays; Uracil Nucleotides; Valine | 1972 |
Aminoacyl transfer RNA formation. II. Comparison of the mechanisms of aminoacylations stimulated by polyamines and Mg 2+ .
Topics: Acylation; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Catalysis; Chromatography, Ion Exchange; Diphosphates; Escherichia coli; Hydroxamic Acids; Isoleucine; Kinetics; Magnesium; Phenylalanine; Phosphorus Isotopes; Polyamines; Putrescine; RNA, Transfer; Spermidine; Spermine; Transfer RNA Aminoacylation; Valine | 1972 |
Evidence for biosynthetical equivalence of the epimeric isoleucine residues in angolide.
Topics: Carbon Isotopes; Chromatography; Culture Media; Infrared Rays; Isoleucine; Mass Spectrometry; Mathematics; Mitosporic Fungi; Optical Rotation; Peptide Biosynthesis; Peptides, Cyclic; Silicon Dioxide; Spectrophotometry; Stereoisomerism; Valine | 1972 |
Classical maple syrup urine disease: cofactor resistance.
Topics: Amino Acids; Carbon Isotopes; Cells, Cultured; Coenzyme A; Coenzymes; Female; Fibroblasts; Flavin-Adenine Dinucleotide; Genetics, Medical; Humans; Infant, Newborn; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; NAD; Pyridoxal Phosphate; Pyruvates; Skin; Thiamine Pyrophosphate; Thioctic Acid; Valine | 1972 |
[Technical problems in the radioimmunologic determination of angiotensin II].
Topics: Angiotensin II; Animals; Antigen-Antibody Complex; Isoleucine; Methods; Rabbits; Radioimmunoassay; Valine | 1971 |
Use of a thermal inactivation technique to obtain binding constants for the Escherichia coli valyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Amines; Amino Acids; Amino Acyl-tRNA Synthetases; Aminobutyrates; Catalysis; Cyclopentanes; Diphosphates; Enzyme Activation; Escherichia coli; Hot Temperature; Isoleucine; Kinetics; Leucine; Magnesium; Mathematics; Phosphorus Isotopes; Protein Binding; Protein Denaturation; Serum Albumin, Bovine; Valine | 1972 |
New specific angiotensin antagonists. (8-Valine)-, (8-isoleucine)-, and chlorambucil-des-1-aspartic,8-valine-angiotensins I.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Chlorambucil; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Isoleucine; Muscle Contraction; Rabbits; Rats; Structure-Activity Relationship; Uterus; Valine | 1973 |
[Comparative study of transfer ribonucleic acids extracted from rat liver and Zajdela hepatoma. I. Study of the acceptor properties of tRNA].
Topics: Acylation; Alanine; Animals; Arginine; Ascites; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Isoleucine; Kinetics; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Transfer; Serine; Transfer RNA Aminoacylation; Valine | 1972 |
I. Pharmacology of angiotensin antagonists.
Topics: Acetamides; Angiotensin II; Animals; Bradykinin; Butyrates; Guanidines; In Vitro Techniques; Isoleucine; Kinetics; Leucine; Male; Piperazines; Rats; Serotonin; Stomach; Valine; Vasodilator Agents; Xylenes | 1973 |
Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida.
Topics: Alcohol Oxidoreductases; Alkanesulfonates; Amino Acids; Camphor; Cell-Free System; Culture Media; Isoleucine; Keto Acids; Leucine; Mutagens; Mutation; Pseudomonas; Stereoisomerism; Succinates; Transaminases; Valine | 1973 |
Mutations affecting growth of the Escherichia coli cell under a condition of DNA polymerase I-deficiency.
Topics: Alkanesulfonates; Coliphages; Conjugation, Genetic; DNA Nucleotidyltransferases; DNA Replication; Escherichia coli; Genes; Genetic Linkage; Genetics, Microbial; Isoleucine; Methionine; Molecular Biology; Mutagens; Mutation; Radiation Genetics; Recombination, Genetic; Suppression, Genetic; Temperature; Transduction, Genetic; Ultraviolet Rays; Valine | 1973 |
Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell.
Topics: Antigens, Viral; Autoradiography; Carbon Radioisotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Humans; Immunodiffusion; Isoleucine; Laryngeal Neoplasms; Leucine; Molecular Weight; Peptide Biosynthesis; Peptides; Poliovirus; Protein Biosynthesis; Simplexvirus; Stereoisomerism; Tritium; Valine; Viral Proteins | 1973 |
Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid.
Topics: Carbon Radioisotopes; Cell-Free System; Chromatography; Enzyme Repression; Histidine; Hydro-Lyases; Isoleucine; Leucine; Mutation; Oxidoreductases; Oxo-Acid-Lyases; Periodic Acid; RNA, Transfer; Salmonella typhimurium; Transaminases; Tritium; Valine | 1974 |
Neurospora arginyl transfer ribonucleic acid ligase. Binding and dissociation of transfer ribonucleic acid.
Topics: Arginine; Binding Sites; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Isoleucine; Kinetics; Lysine; Neurospora; Neurospora crassa; Periodic Acid; Phosphorus Radioisotopes; Polynucleotide Ligases; Protein Binding; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Time Factors; Tritium; Ultrafiltration; Valine | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II.
Topics: Adrenal Glands; Adrenalectomy; Aminopeptidases; Angiotensin II; Animals; Aorta; Aspartic Acid; Blood Pressure; Cats; Colon; Endopeptidases; Gastrointestinal Motility; Half-Life; Heart; In Vitro Techniques; Isoleucine; Muscle Contraction; Perfusion; Rabbits; Rats; Sarcosine; Valine | 1974 |
Molecular orbital studies of the conformation around the 5 position in angiotensin II.
Topics: Alanine; Aminobutyrates; Angiotensin II; Chemical Phenomena; Chemistry, Physical; Cyclohexanes; Cyclopentanes; Glycine; Isoleucine; Molecular Conformation; Norleucine; Valerates; Valine | 1974 |
Mutants of Salmonella typhimurium defective in transport of branched-chain amino acids.
Topics: Alkanesulfonates; Amino Acids; Biological Transport, Active; Carbon Radioisotopes; Chromosome Mapping; Conjugation, Genetic; Dipeptides; Genes; Isoleucine; Leucine; Mesylates; Mutagens; Mutation; Salmonella typhimurium; Stereoisomerism; Transduction, Genetic; Valine | 1974 |
Micelles as simple models of drug receptors.
Topics: Acetylcholine; Adsorption; Alanine; Aminobutyrates; Betaine; Isoleucine; Models, Chemical; Peptides; Quaternary Ammonium Compounds; Receptors, Drug; Valine | 1967 |
Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37 Rv.
Topics: Ascorbic Acid; Cell-Free System; Chromatography, Paper; Chromatography, Thin Layer; Glutathione; Hydro-Lyases; Hydroquinones; Indophenol; Infrared Rays; Isoleucine; Lactates; Ligases; Mycobacterium tuberculosis; NADP; Oxidoreductases; Spectrum Analysis; Valine; Vitamin B 12 | 1968 |
Levels of resistance in ribosomes from genetically linked, streptomycin-resistant mutants of pneumococcus.
Topics: Carbon Isotopes; Cell-Free System; Drug Resistance, Microbial; Genetics, Microbial; Isoleucine; Magnesium; Mutation; Phenylalanine; Polynucleotides; Ribosomes; RNA, Messenger; Streptococcus pneumoniae; Streptomycin; Tritium; Valine | 1968 |
[Studies on "branched chain oxoacid aciduria" (maple syrup diseases)].
Topics: Child, Preschool; Coenzyme A; D-Amino-Acid Oxidase; Female; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Oxidoreductases; Valine | 1966 |
Influence of dietary protein levels and hydrocortisone administration on the branched-chain amino acid transaminase activity in rat tissues.
Topics: Animals; Caseins; Dietary Proteins; Hydro-Lyases; Hydrocortisone; Intestines; Isoleucine; Kidney; Leucine; Liver; Male; Muscles; Rats; Transaminases; Tryptophan Oxygenase; Tyrosine Transaminase; Valine | 1968 |
[Inactivation experiments with homozygous yeast strains of different degrees of ploidy. X. The "AS-effect", a short-time repair effect].
Topics: Diploidy; Genetics, Microbial; Homozygote; Isoleucine; Mutation; Radiation Genetics; Radiobiology; Saccharomyces; Valine | 1968 |
Purification and properties of the acetohydroxy acid isomeroreductase of Salmonella typhimurium.
Topics: Animals; Antigens; Ascorbic Acid; Binding Sites; Carbon Isotopes; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Isoleucine; Isomerases; Keto Acids; Lactates; Magnesium; Methods; Molecular Weight; NADP; Rabbits; Salmonella typhimurium; Tritium; Ultracentrifugation; Valerates; Valine; Vibration | 1969 |
[Further studies on the amino acid sequence of melittin, II. Preferential cleavage of valine-, leucine- and isoleucine bonds by alpha-protease from Crotalus atrox venom].
Topics: Amino Acid Sequence; Animals; Bees; Chemical Phenomena; Chemistry; Indicators and Reagents; Isoleucine; Leucine; Peptide Hydrolases; Peptides; Snakes; Valine; Venoms | 1969 |
Valine activation of feeding in the sea anemone Boloceroides.
Topics: Amino Acids; Animals; Chromatography; Cnidaria; Crustacea; Feeding Behavior; Isoleucine; Leucine; Seawater; Time Factors; Valine | 1968 |
Effect of force-feeding diets lacking leucine, valine, isoleucine, threonine or methionine on amino acid catabolism in rats.
Topics: Adrenal Cortex Hormones; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Deficiency Diseases; Digestive System; Isoleucine; Leucine; Liver; Male; Metabolism; Methionine; Nicotinic Acids; Nitrogen; Rats; Solubility; Stimulation, Chemical; Threonine; Time Factors; Trichloroacetic Acid; Tryptophan Oxygenase; Tyrosine Transaminase; Valine | 1971 |
Mutant strains of Escherichia coli K12 that use D-amino acids.
Topics: Amino Acids; Arginine; Chromosome Mapping; Coliphages; D-Amino-Acid Oxidase; Escherichia coli; Genetic Linkage; Genotype; Histidine; Isoleucine; Isomerism; Leucine; Lysine; Mutation; Phenylalanine; Proline; Serine; Threonine; Transduction, Genetic; Tryptophan; Tyrosine; Valine | 1971 |
An isoleucine-valine substitution in the beta chain of rabbit hemoglobin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Formates; Genetic Variation; Hemoglobins, Abnormal; Isoleucine; Lysine; Peptide Fragments; Spectrophotometry, Ultraviolet; Thiocyanates; Tritium; Valine | 1974 |
Amino acid imbalance in cystinuria.
Topics: Adult; Amino Acids; Arginine; Cystinuria; Dietary Proteins; Humans; Isoleucine; Lysine; Methionine; Valine | 1974 |
Kinetic properties of pyruvate kinases from turtle liver and heart.
Topics: Alanine; Allosteric Regulation; Animals; Binding Sites; Citrates; Cysteine; Enzyme Activation; Fructosephosphates; Hexosediphosphates; Hydrogen-Ion Concentration; Isoleucine; Ketoglutaric Acids; Kinetics; Liver; Magnesium; Methionine; Myocardium; Organ Specificity; Phenylalanine; Phosphoenolpyruvate; Protein Binding; Pyruvate Kinase; Serine; Succinates; Tryptophan; Turtles; Valine | 1974 |
Rate of synthesis of albumin in relation to serum levels of essential amino acids in patients with bacterial overgrowth in the small bowel.
Topics: Adult; Aged; Air; Albumins; Amino Acids, Essential; Carbon Radioisotopes; Crohn Disease; Female; Glycocholic Acid; Humans; Ileum; Intestinal Diseases; Intestinal Obstruction; Intestinal Secretions; Intestine, Small; Isoleucine; Jejunum; Leucine; Liver Function Tests; Lysine; Male; Middle Aged; Respiration; Tryptophan; Valine; Vitamin B 12 | 1974 |
Glycemic response to 24-hour fast in normal children and children with ketotic hypoglycemia: II. Hormonal and metabolic changes.
Topics: Acidosis; Alanine; Amino Acids; Autoanalysis; Blood Glucose; Child; Child, Preschool; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypoglycemia; Insulin; Isoleucine; Ketones; Ketosis; Leucine; Male; Valine | 1974 |
Evidence for polypeptide synthesis in the caiman from mixtures deficient in essential amino acids.
Topics: Amino Acids; Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Cycloheximide; Fishes; Half-Life; Insulin; Isoleucine; Lysine; Methionine; Muscle Proteins; Peptide Biosynthesis; Phenylalanine; Reptiles; Threonine; Time Factors; Valine | 1974 |
Repression of the branched-chain amino acid biosynthetic enzymes in developing conidia and mycelia of Neurospora.
Topics: Cell Division; Enzyme Activation; Enzyme Repression; Hydro-Lyases; Hydroxy Acids; Isoleucine; Leucine; Neurospora; Oxo-Acid-Lyases; Pyruvates; Time Factors; Transaminases; Valine | 1974 |
Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects.
Topics: Amino Acids; Female; Humans; Infusions, Parenteral; Isoleucine; Keto Acids; Leucine; Methionine; Nitrogen; Obesity; Phenylalanine; Starvation; Urea; Valine | 1974 |
Cross-linking of the spike glycoproteins in Semliki Forest virus with dimethylsuberimidate.
Topics: Centrifugation, Zonal; Dicarboxylic Acids; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Imides; Indicators and Reagents; Isoleucine; Leucine; Membranes; Methionine; Polyethylene Glycols; Semliki forest virus; Sodium Dodecyl Sulfate; Sulfur Radioisotopes; Tritium; Valine; Viral Proteins | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
The covalent structure of collagen: amino acid sequence of the N-terminal region of alpha2-CB3 from rat skin collagen and alpha2-CB3.5 from calf skin collagen.
Topics: Amino Acid Sequence; Animals; Autoanalysis; Cattle; Chromatography; Collagen; Cyanogen Bromide; Isoleucine; Lathyrism; Leucine; Methionine; Peptide Chain Termination, Translational; Phenylalanine; Rats; Skin; Species Specificity; Valine | 1974 |
Immunological characterization of rabbit hemoglobin alpha and beta chain-synthesizing polysomes.
Topics: Animals; Antibodies; Binding Sites, Antibody; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Ion Exchange; Goats; Hemoglobins; Iodine Radioisotopes; Isoleucine; Kinetics; Molecular Weight; Peptide Biosynthesis; Polyribosomes; Precipitin Tests; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Spectrophotometry, Ultraviolet; Tritium; Valine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
Control of brain serotonin by the diet.
Topics: Animals; Blood Glucose; Brain; Circadian Rhythm; Dietary Carbohydrates; Dietary Proteins; Fatty Acids, Nonesterified; Indoles; Insulin; Isoleucine; Leucine; Phenylalanine; Protein Binding; Rats; Serotonin; Time Factors; Tryptophan; Tyrosine; Valine | 1974 |
[The effect of the feedback inhibition of threonine deaminase on valine-leucine biosynthesis (author's transl)].
Topics: Arthrobacter; Butyrates; Chromatography, Gas; Chromatography, Thin Layer; Enzyme Repression; Feedback; Hydro-Lyases; Isoleucine; Lactates; Leucine; Mass Spectrometry; Mutation; Threonine; Time Factors; Valine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Alpha-aminocyclic and bicyclic alkane carboxylic acids: differential effects on selected amino acids of rat brain cortex.
Topics: Amines; Amino Acids; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carboxylic Acids; Cerebral Cortex; Cyclohexanecarboxylic Acids; Cycloparaffins; Cysteine; Isoleucine; Male; Methionine; Phenylalanine; Rats; Structure-Activity Relationship; Time Factors; Tyrosine; Valine | 1974 |
The structural code for proteins: zonal distribution of amino acid residues and stabilization of helices by hydrophobic triplets.
Topics: Alanine; Amino Acids; Aspartic Acid; Computers; Isoleucine; Leucine; Mathematics; Models, Molecular; Proline; Protein Conformation; Statistics as Topic; Tyrosine; Valine | 1974 |
Protein synthesis in phenotypically different, single neurons of Aplysia.
Topics: Animals; Electrophoresis; Electrophoresis, Polyacrylamide Gel; Ganglia; Isoleucine; Isotope Labeling; Kinetics; Leucine; Methionine; Methods; Molecular Weight; Mollusca; Nerve Tissue Proteins; Neurons; Phenotype; Phenylalanine; Sodium Dodecyl Sulfate; Spectrum Analysis; Tritium; Valine | 1974 |
Nicotinic acid deficiency in dogs with and without supplementary leucine in their diets.
Topics: Animal Nutritional Physiological Phenomena; Animals; Antimetabolites; Deficiency Diseases; Dogs; Isoleucine; Leucine; Nicotinic Acids; Time Factors; Valine | 1974 |
Inhibition by the branched-chain 2-oxo acids of the 2-oxoglutarate dehydrogenase complex in developing rat and human brain.
Topics: Age Factors; Animals; Brain; Carbon Dioxide; Decarboxylation; Humans; Isoleucine; Keto Acids; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Leucine; Maple Syrup Urine Disease; Mitochondria; Molecular Conformation; Rats; Valine | 1974 |
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo.
Topics: Alanine; Animals; Aspartic Acid; Chemical Fractionation; Chick Embryo; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Proline; Ribonucleases; RNA, Transfer; Serine; Tyrosine; Valine | 1974 |
Analysis of isoaccepting tRNAs during the growth phase mitotic cycle of Physarum polycephalum.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Asparagine; Cell Division; Chromatography, Ion Exchange; Codon; Genetic Code; Glycine; Histidine; Isoleucine; Leucine; Mitosis; Myxomycetes; Protein Biosynthesis; RNA, Transfer; Tritium; Tryptophan; Valine | 1974 |
[Distribution of antienoplastic amino acid-related compounds in mice--study by whole body autoradiography of the frozen material].
Topics: Animals; Autoradiography; Bile; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Female; Fluorenes; Freezing; Isoleucine; Kidney; Liver; Lung; Male; Mice; Neoplasm Transplantation; Ovary; Phenylalanine; Salivary Glands; Sarcoma 180; Sarcoma, Experimental; Skin; Spleen; Tryptophan; Urinary Bladder; Uterus; Valine | 1974 |
Preformed protein sources in steer finishing rations.
Topics: Amino Acids; Ammonia; Animal Feed; Animals; Blood Urea Nitrogen; Cattle; Dietary Proteins; Fatty Acids, Volatile; Fish Products; Glutamates; Glycine; Glycine max; Isoleucine; Linseed Oil; Male; Rumen; Silage; Valine; Zea mays | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
3-hydroxypropionate: significance of -oxidation of propionate in patients with propionic acidemia and methylmalonic acidemia.
Topics: Acidosis; Carbon Isotopes; Chromatography; Chromatography, Paper; Citrates; Humans; Hydroxylation; Injections, Intravenous; Isoleucine; Malonates; Mass Spectrometry; Metabolism, Inborn Errors; Oxidation-Reduction; Propionates; Valine | 1972 |
The structure and synthesis of malformin A.
Topics: Amino Acid Sequence; Cystine; Disulfides; Hydrolysis; Isoleucine; Leucine; Oligopeptides; Peptides, Cyclic; Plants; Protein Conformation; Valine | 1974 |
Genetic analysis of the leucine biosynthetic genes and their relationship to the ilv gene cluster.
Topics: Bacteriophage Typing; Genes; Genetic Complementation Test; Genetic Linkage; Isoleucine; Leucine; Molecular Biology; Mutagens; Mutation; Nitrosoguanidines; Staphylococcus; Stereoisomerism; Transduction, Genetic; Valine | 1974 |
Location of the spike glycoproteins in the Semliki Forest virus membrane.
Topics: Centrifugation, Density Gradient; Electrophoresis; Glycoproteins; Isoleucine; Leucine; Membranes; Microscopy, Electron; Peptides; Protein Conformation; Semliki forest virus; Sulfones; Sulfur Radioisotopes; Tritium; Valine | 1974 |
Discussion paper: increased synthesis of one type of globin chain resulting from inhibiting synthesis of the opposite type.
Topics: Amino Acids; Animals; Female; Fetal Hemoglobin; Genotype; Globins; Hemoglobins, Abnormal; Homozygote; Humans; Isoleucine; Lysine; Mutation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polyribosomes; Pregnancy; Rabbits; Spectrophotometry, Ultraviolet; Threonine; Tritium; Valine | 1974 |
Kinetic studies on the reaction catalysed by threonine dehydratase from Rhodopseudomonas spheroides.
Topics: Allosteric Regulation; Binding Sites; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Mathematics; Models, Chemical; Pyridoxal Phosphate; Rhodobacter sphaeroides; Rhodopseudomonas; Stereoisomerism; Threonine; Valine | 1972 |
Effects of phenethyl alcohol on phospholipid metabolism in Escherichia coli.
Topics: Acetates; Alcohols; Bacterial Proteins; Benzene Derivatives; Carbon Isotopes; Chloramphenicol; Chromatography, Thin Layer; Culture Media; DNA, Bacterial; Escherichia coli; Isoleucine; Lipids; Nalidixic Acid; Phenylalanine; Phosphatidylethanolamines; Phospholipids; RNA, Bacterial; Thymine; Tritium; Uracil; Valine | 1972 |
Ordering of mutant sites in the isoleucine-valine genes of Escherichia coli by use of merogenotes derived from F 14 : a new procedure for fine-structure mapping.
Topics: Chromosome Mapping; Culture Media; DNA, Bacterial; Escherichia coli; Genes; Genetic Complementation Test; Haploidy; Hydro-Lyases; Isoleucine; Isomerases; Lyases; Methods; Mutation; Recombination, Genetic; Threonine; Transaminases; Transduction, Genetic; Valine | 1972 |
Rapid deacylation by isoleucyl transfer ribonucleic acid synthetase of isoleucine-specific transfer ribonucleic acid aminoacylated with valine.
Topics: Acylation; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Hydrolysis; Isoleucine; Kinetics; Phenylalanine; Phosphorus Isotopes; RNA, Transfer; Tritium; Valine | 1972 |
Two forms of biosynthetic acetohydroxy acid synthetase in Salmonella typhimurium.
Topics: Chromatography; Chromatography, Gel; Enzyme Repression; Feedback; Genetics, Microbial; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxyapatites; Isoleucine; Leucine; Lyases; Mutation; Pyruvates; Salmonella typhimurium; Threonine; Valine | 1972 |
Isoleucine and valine metabolism in Escherichia coli. XX. Multiple forms of acetohydroxy acid synthetase.
Topics: Centrifugation, Density Gradient; Enzyme Repression; Escherichia coli; Feedback; Genetics, Microbial; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lyases; Mutation; Pyruvates; Salmonella typhimurium; Valine | 1972 |
Regulation of the formation of isoleucyl-tRNA-synthetase and the level of isoleucine biosynthetic enzymes in E. coli K12.
Topics: Amino Acyl-tRNA Synthetases; Enzymes; Escherichia coli; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Molecular Biology; Mutation; Threonine; Valine | 1972 |
Isoleucine and valine metabolism in Escherichia coli. 18. Induction of acetohydroxy acid isomeroreductase.
Topics: Cell-Free System; Chloramphenicol; Culture Media; Enzyme Induction; Enzyme Repression; Escherichia coli; Glucose; Glycerol; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoleucine; Isomerases; Lactates; Lyases; Microbiology; Mutation; Rifampin; Threonine; Valine | 1972 |
Isoleucine and valine metabolism in Escherichia coli. XIX. Inhibition of isoleucine biosynthesis by glycyl-leucine.
Topics: Acylation; Cell-Free System; Chloramphenicol; Culture Media; Dipeptides; Drug Resistance, Microbial; Escherichia coli; Glycine; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Operon; Pyruvates; Rifampin; Threonine; Valine | 1972 |
Isoleucine auxotrophy due to feedback hypersensitivity of biosynthetic threonine deaminase.
Topics: Cell-Free System; Culture Media; Feedback; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Mutagens; Mutation; Nitrosoguanidines; Salmonella typhimurium; Threonine; Transaminases; Tritium; Valine | 1972 |
Isolation of transducing bacteriophages for the histidine and isoleucine-valine operons in Escherichia coli K-12.
Topics: Centrifugation, Density Gradient; Colicins; Coliphages; DNA, Viral; Escherichia coli; Histidine; Isoleucine; Lysogeny; Mutation; Operon; Temperature; Thymidine; Transduction, Genetic; Tritium; Valine | 1972 |
The action of O-methyl-threonine and thiaisoleucine on threonine deaminase purified from Escherichia coli K-12.
Topics: Amino Acids; Aminohydrolases; Binding Sites; Chromatography; Chromatography, DEAE-Cellulose; Escherichia coli; Hydroxyapatites; Isoleucine; Mathematics; Methylation; Sulfides; Threonine; Valine | 1972 |
The role of the fourth nucleotide from the 3'end in the yeast phenylalanyl transfer RNA synthetase recognition site: requirement for adenosine.
Topics: Acetylation; Adenosine; Amino Acyl-tRNA Synthetases; Base Sequence; Benzoates; Binding Sites; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Glycine; Glycolates; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Valine; Yeasts | 1972 |
Derepression of isoleucine-valine biosynthetic enzymes and extracellular isoleucine accumulation in Serratia marcescens.
Topics: Aminoisobutyric Acids; Depression, Chemical; Enzyme Repression; Hydro-Lyases; Isoleucine; Isomerism; Keto Acids; Leucine; Mutation; Serratia marcescens; Threonine; Transaminases; Valine | 1972 |
Derepressed leucine transport activity in Escherichia coli.
Topics: Bacterial Proteins; Biological Transport; Culture Media; Escherichia coli; Isoleucine; Leucine; Mutation; Protein Binding; Valine | 1972 |
A simple preparative polyacrylamide disc gel electrophoresis apparatus: purification of three branched-chain amino acid binding proteins from Escherichia coli.
Topics: Bacterial Proteins; Buffers; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Isoleucine; Leucine; Methods; Protein Binding; Valine | 1973 |
Temperature-sensitive relaxed Phenotype in a stringent strain of Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Escherichia coli; Isoleucine; Mutation; Peptide Biosynthesis; Peptide Elongation Factors; Phenotype; Phenylalanine; Recombination, Genetic; RNA, Bacterial; RNA, Transfer; Temperature; Transduction, Genetic; Tritium; Uracil; Uridine; Valine | 1973 |
Leucine accumulation by isoleucine revertants of Serratia marcescens resistant to -aminobutyric acid: lack of both feedback inhibition and repression.
Topics: Acetyltransferases; Aminobutyrates; Dicarboxylic Acids; Enzyme Repression; Feedback; Hydro-Lyases; Isoleucine; Leucine; Mutation; Serratia marcescens; Valerates; Valine | 1973 |
Involvement of threonine deaminase in repression of the isoleucine-valine and leucine pathways in Saccharomyces cerevisiae.
Topics: Culture Media; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Hydro-Lyases; Isoleucine; Isomerases; Leucine; Lyases; Models, Chemical; Mutation; Pyruvates; Recombination, Genetic; Saccharomyces cerevisiae; Valine | 1973 |
pH-dependent intermediate plateaux in the kinetics of the reaction catalyzed by "biosynthetic" L-threonine dehydratase of Escherichia coli K-12.
Topics: Allosteric Regulation; Binding Sites; Chlorides; Culture Media; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Isomerism; Kinetics; L-Lactate Dehydrogenase; Macromolecular Substances; Mercury; Osmolar Concentration; Species Specificity; Threonine; Valine | 1973 |
Isoleucine and valine metabolism in Escherichia coli. XXI. Mutations affecting derepression and valine resistance.
Topics: Centrifugation, Density Gradient; Culture Media; Enzyme Repression; Escherichia coli; Genes, Regulator; Genetic Linkage; Hydro-Lyases; Hydroxybutyrates; Isoleucine; Isomerases; Lactates; Mutation; Nitrosoguanidines; Oxo-Acid-Lyases; Pyruvates; Transduction, Genetic; Valine | 1973 |
Isoleucine and valine metabolism in Escherichia coli. XXII. A pleiotropic mutation affecting induction of isomeroreductase activity.
Topics: Enzyme Induction; Enzyme Repression; Escherichia coli; Feedback; Genes; Genes, Regulator; Genetic Complementation Test; Genetic Linkage; Hydro-Lyases; Hydroxybutyrates; Isoleucine; Isomerases; Lactates; Mutation; Oxo-Acid-Lyases; Pyruvates; Recombination, Genetic; Transduction, Genetic; Valine | 1973 |
A role for a pyridoxne derivative in the multivalent repression of the isoleucine and valine biosynthetic enzymes.
Topics: Apoproteins; Enzyme Repression; Escherichia coli; Hydro-Lyases; Isoleucine; Mutation; Pyridoxine; Threonine; Valine; Vitamin B 6 Deficiency | 1973 |
Affinity elution as a purification method for aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Cellulose; Chromatography; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Ion Exchange Resins; Isoleucine; Ligands; Methods; Phenylalanine; Phosphates; Protein Binding; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sodium Dodecyl Sulfate; Transfer RNA Aminoacylation; Valine | 1973 |
Common mechanism for repellents and attractants in bacterial chemotaxis.
Topics: Acetates; Amino Acids; Butyrates; Chemotaxis; Fatty Acids, Volatile; Indoles; Isoleucine; Leucine; Phenols; Propionates; Salmonella typhimurium; Tryptophan; Tyrosine; Valine | 1973 |
Messenger ribonucleic acid stability in relaxed and stringent Escherichia coli starved for methionine.
Topics: Centrifugation, Density Gradient; Escherichia coli; Isoleucine; Methionine; Mutation; Nucleic Acid Hybridization; Rifampin; RNA, Bacterial; RNA, Messenger; Tritium; Uridine; Valine | 1973 |
Transport of sugars and amino acids in bacteria. VI. Changes induced by valine in the branched chain amino acid transport systems of Escherichia coli.
Topics: Amino Acids; Biological Transport, Active; Culture Media; Escherichia coli; Isoleucine; Leucine; Ligases; Valine | 1973 |
On the role of isoleucyl-tRNA synthetase in multivalent repression.
Topics: Amino Acyl-tRNA Synthetases; Carbon Isotopes; Drug Resistance, Microbial; Extrachromosomal Inheritance; Hydro-Lyases; Isoleucine; Kinetics; Mutation; Radiation Effects; Salmonella Phages; Salmonella typhimurium; Suppression, Genetic; Threonine; Transduction, Genetic; Trimethoprim; Ultraviolet Rays; Valine | 1972 |
Ultracentrifuge studies on binding of aliphatic amino acids to isoleucyl-tRNA synthetase from Escherichia coli MRE 600.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Aminobutyrates; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Glycine; Isoleucine; Kinetics; Leucine; Macromolecular Substances; Stereoisomerism; Ultracentrifugation; Valine | 1973 |
Autoregulation: a role for a biosynthetic enzyme in the control of gene expression.
Topics: Enzyme Induction; Enzyme Repression; Feedback; Genes; Hydro-Lyases; Hydroxybutyrates; Isoleucine; Isomerases; Lactates; Leucine; Molecular Biology; Operon; Salmonella typhimurium; Threonine; Valine | 1973 |
Temperature-sensitive growth inhibition by valine in Salmonella typhimurium: alteration of one form of acetohydroxy acid synthetase.
Topics: Alcohol Oxidoreductases; Chromatography; Chromosome Mapping; Genes; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxyapatites; Isoleucine; Isomerases; Lyases; Mutation; Pyruvates; Recombination, Genetic; Salmonella typhimurium; Temperature; Transaminases; Transduction, Genetic; Valine | 1973 |
Pseudoverification. Hydrolysis of aminoacyl transfer ribonucleic acid catalyzed by an aminoacyl transfer ribonucleic acid synthetase in mixed solvents.
Topics: Acylation; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Chromatography, Thin Layer; Drug Stability; Escherichia coli; Hydrolysis; Isoleucine; Kinetics; Methanol; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Time Factors; Transfer RNA Aminoacylation; Tritium; Valine | 1973 |
Kinetics of homologous and heterologous aminoacylation with yeast phenylalanyl transfer ribonucleic acid synthetase.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Base Sequence; Binding Sites; Carbon Radioisotopes; Chromatography; Chromatography, DEAE-Cellulose; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lysine; Methionine; Nucleic Acid Conformation; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Transfer RNA Aminoacylation; Triticum; Valine | 1973 |
Multiplicity of leucine transport systems in Escherichia coli K-12.
Topics: Alanine; Bacterial Proteins; Biological Transport, Active; Chromatography, DEAE-Cellulose; Escherichia coli; Isoleucine; Leucine; Mutation; Nitrosoguanidines; Osmosis; Protein Binding; Serine; Stereoisomerism; Threonine; Transduction, Genetic; Valine | 1973 |
Detection of inosine-containing transfer ribonucleic acid species by affinity chromatography on columns of anti-inosine antibodies.
Topics: Alkylation; Animals; Antibodies; Arginine; Carbon Radioisotopes; Chromatography, Affinity; Cyanides; Escherichia coli; Evaluation Studies as Topic; Guanosine; Inosine; Isoleucine; Methionine; Methods; Proline; Rabbits; RNA, Bacterial; RNA, Transfer; Serine; Structure-Activity Relationship; Threonine; Transfer RNA Aminoacylation; Tritium; Valine | 1973 |
Role of threonine deaminase in the regulation of isoleucine and valine biosynthesis.
Topics: Amino Acyl-tRNA Synthetases; Chromosome Mapping; Coliphages; Enzyme Induction; Enzyme Repression; Escherichia coli; Genes; Genes, Regulator; Hydro-Lyases; Isoleucine; Isomerases; Lactates; Leucine; Mutation; Operon; Oxo-Acid-Lyases; Pyruvates; Threonine; Transduction, Genetic; Valine | 1973 |
Function of N2 methylguanine in phenylalanine transfer RNA.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine | 1973 |
Role for free isoleucine of glycyl-leucine in the repression of threonine deaminase in Escherichia coli.
Topics: Cell-Free System; Dipeptides; Enzyme Repression; Escherichia coli; Genes; Glycine; Hydro-Lyases; Isoleucine; Leucine; Mutation; Threonine; Valine | 1974 |
Inactivation of valine acceptor ativity by a C-U missense change in the anticodon of yeast valine transfer ribonucleic acid.
Topics: Base Sequence; Chromatography, DEAE-Cellulose; Cytosine; Genetic Code; Isoleucine; Nucleotides; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Sulfites; Uracil Nucleotides; Valine | 1973 |
Autogenous regulation of gene expression.
Topics: Alkaline Phosphatase; Allosteric Regulation; Animals; Arginine; Aspergillus nidulans; Bacteriophages; Escherichia coli; Feedback; Genes; Genes, Regulator; Histidine; Humans; Hydro-Lyases; Isoleucine; L-Serine Dehydratase; Mice; Mutation; Operon; Ornithine; RNA, Transfer; Saccharomyces cerevisiae; Salmonella typhimurium; Transaminases; Tryptophan; Valine | 1974 |
Multiplicity of isoleucine, leucine, and valine transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Biological Transport, Active; Carbon Radioisotopes; Escherichia coli; Isoleucine; Leucine; Methionine; Mutation; Threonine; Valine | 1974 |
Mutations affecting the different transport systems for isoleucine, leucine, and valine in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Bacterial Proteins; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Genes; Isoleucine; Leucine; Methionine; Mutagens; Mutation; Nitrosoguanidines; Threonine; Transduction, Genetic; Ultraviolet Rays; Valine | 1974 |
Effect of adenosine on methionyl-tRNA synthetase.
Topics: Adenosine; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Cysteine; Escherichia coli; Isoleucine; Kinetics; Magnesium; Methionine; Phenylalanine; Phosphates; Serine; Trypsin; Valine | 1973 |
[The formation of higher alcohols by amino acid auxotrophic mutants of Saccharomyces cerevisiae. I. The conversion of amino acids to higher alcohols (author's transl)].
Topics: 1-Propanol; Alcohols; Amino Acids; Butanols; Culture Media; Fermentation; Glucose; Isoleucine; Leucine; Mutation; Nitrogen; Saccharomyces cerevisiae; Threonine; Time Factors; Valine | 1973 |
Unfolding of yeast transfer ribonucleic acid species caused by addition of organic solvents and studied by circular dichroism.
Topics: Arsenicals; Buffers; Circular Dichroism; Crystallization; Dioxins; Ethanol; Glycols; Hexanols; Isoleucine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sodium Chloride; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Temperature; Tyrosine; Urea; Valine | 1974 |
Control of serine transhydroxymethylase synthesis in Escherichia coli K12.
Topics: Adenine; Culture Media; Escherichia coli; Formates; Glycine; Guanine; Histidine; Isoleucine; Methionine; Mutation; Serine; Thymidine; Transferases; Tritium; Valine | 1974 |
A deae-cellulose filter disk assay for aminoacyl-tRNA.
Topics: Acetates; Alanine; Amino Acyl-tRNA Synthetases; Aspartic Acid; Cellulose; Citrates; Electrophoresis, Disc; Escherichia coli; Evaluation Studies as Topic; Filtration; Glutamates; Glycine; Isoleucine; Lysine; Methionine; Methods; Microchemistry; Phenylalanine; Phosphates; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Tritium; Tyrosine; Valine | 1974 |
flrB, a regulatory locus controlling branched-chain amino acid biosynthesis in Salmonella typhimurium.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Autoanalysis; Cell-Free System; Chromatography; Chromosome Mapping; Dicarboxylic Acids; Genes, Regulator; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Oxo-Acid-Lyases; Pyruvates; RNA, Bacterial; RNA, Transfer; Salmonella typhimurium; Temperature; Threonine; Transduction, Genetic; Valerates; Valine | 1974 |
Regulation of isoleucine-valine biosynthesis in an ilvDAC deletion strain of Escherichia coli K-12.
Topics: Cell Division; Crosses, Genetic; Escherichia coli; Genes; Genes, Regulator; Genotype; Isoleucine; Leucine; Mutation; Time Factors; Valine | 1974 |
Activation of several tRNAs of Escherichia coli by the phenoxyacetyl derivative of N-hydroxysuccinimide.
Topics: Acylation; Arginine; Carbon Radioisotopes; Chloramphenicol; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Glutamates; Isoleucine; Leucine; Methionine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Phenyl Ethers; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Spectrophotometry, Ultraviolet; Succinimides; Tritium; Valine | 1974 |
[The formation of higher alcohols by amino acid auxotrophic mutants of Saccharomyces cerevisiae. II. The influence of threonine, isoleucine, valine and leucine (author's transl)].
Topics: 1-Propanol; Alcohols; Amino Acids; Butanols; Chromatography, Gas; Chromatography, Ion Exchange; Fermentation; Isoleucine; Ketoglutaric Acids; Leucine; Mutation; Pyruvates; Saccharomyces cerevisiae; Threonine; Valine | 1974 |
3-(3-amino-3-carboxy-n-propyl)uridine. The structure of the nucleoside in Escherichia coli transfer ribonucleic acid that reacts with phenoxyacetoxysuccinimide.
Topics: Aminobutyrates; Arginine; Base Sequence; Carbon Radioisotopes; Coliphages; DNA Viruses; Escherichia coli; Ethers; Glycolates; Isoleucine; Methionine; Oligonucleotides; Pancreas; Phenylalanine; Ribonucleases; RNA, Bacterial; RNA, Transfer; Succinimides; Uridine; Valine | 1974 |
Effects of methionine deprivation of Newcastle disease virus in chicken embryo cells.
Topics: Animals; Antigens, Viral; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Culture Media; Fluorescent Antibody Technique; Hemagglutinins, Viral; Isoleucine; Methionine; Methylation; Methyltransferases; Newcastle disease virus; RNA, Viral; Tritium; Valine; Viral Proteins | 1974 |
Correlation between guanosine tetraphosphate accumulation and degree of amino acid control of ribonucleic acid accumulation during nutritionally slowed growth in Escherichia coli.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Escherichia coli; Glucose; Guanine Nucleotides; Isoleucine; Mutation; Phenylalanine; Phosphorus Radioisotopes; RNA, Bacterial; Spectrophotometry; Time Factors; Valine | 1974 |
Complementation between different mutations in the ilvA gene of Escherichia coli K-12.
Topics: Crosses, Genetic; Escherichia coli; Genes; Genetic Complementation Test; Hydro-Lyases; Isoleucine; Mutation; Threonine; Transduction, Genetic; Valine | 1974 |
Derepression of synthesis of the aminoacyl-transfer ribonucleic acid synthetases for the branched-chain amino acids of Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chloramphenicol; Enzyme Repression; Escherichia coli; Isoleucine; Leucine; Rifampin; Valine | 1974 |
Fine structure analysis of a eukaryotic multifunctional gene.
Topics: Alleles; Chromosome Mapping; Enzyme Repression; Genes; Genes, Regulator; Genetic Code; Genotype; Hydro-Lyases; Isoleucine; Mutation; Peptide Chain Termination, Translational; Protein Biosynthesis; Saccharomyces cerevisiae; Valine | 1974 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Enhancement of Tb(III) and Eu(III) fluorescence in complexes with Escherichia coli tRNA.
Topics: Amino Acyl-tRNA Synthetases; Binding Sites; Carbon Radioisotopes; Chromatography, Ion Exchange; Escherichia coli; Europium; Glutamates; Isoleucine; Magnesium; Methionine; Phenylalanine; Protein Binding; Protein Conformation; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Terbium; Tritium; Valine | 1974 |
Mutant of Escherichia coli K-12 missing acetolactate synthase activity.
Topics: Chromosome Mapping; Escherichia coli; Genes; Isoenzymes; Isoleucine; Mutation; Oxo-Acid-Lyases; Phenotype; Transduction, Genetic; Valine | 1974 |
Transport of biosynthetic intermediates: regulation of homoserine and threonine uptake in Escherichia coli.
Topics: Alanine; Amino Acids; Bacterial Proteins; Biological Transport, Active; Carbon Radioisotopes; Chloramphenicol; Depression, Chemical; Escherichia coli; Homoserine; Isoleucine; Leucine; Methionine; Threonine; Valine | 1974 |
The threonine dehydratase structural gene in Aspergillus nidulans.
Topics: Alleles; Aspergillus nidulans; Cell-Free System; Cold Temperature; Drug Stability; Genes; Hydro-Lyases; Isoleucine; Kinetics; Mutation; Temperature; Threonine; Valine | 1974 |
Regulation of the pool size of valine in Escherichia coli K-12.
Topics: Cell-Free System; Chromosome Mapping; Drug Resistance, Microbial; Escherichia coli; Genes; Hydro-Lyases; Isoleucine; Isomerases; Leucine; Mutagens; Mutation; Nitrosoguanidines; Oxo-Acid-Lyases; Phenotype; Threonine; Transduction, Genetic; Ultraviolet Rays; Valine | 1974 |
Structural genes for a newly recognized acetolactate synthase in Escherichia coli K-12.
Topics: Cell-Free System; Escherichia coli; Genes; Genetic Complementation Test; Isoenzymes; Isoleucine; Mutation; Oxo-Acid-Lyases; Temperature; Transduction, Genetic; Ultraviolet Rays; Valine | 1974 |
Regulation of synthesis of the branched-chain amino acids and cognate aminoacyl-transfer ribonucleic acid synthetases of Escherichia coli: a common regulatory element.
Topics: Alcohol Oxidoreductases; Amino Acids; Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Cell-Free System; Enzyme Repression; Escherichia coli; Fluorine; Genes, Regulator; Hydro-Lyases; Isoleucine; Leucine; Ligases; Mutation; Threonine; Valine | 1974 |
Conformation and functioning of tRNAs: cross-linked tRNAs as substrate for tRNA nucleotidyl-transferase and aminoacyl synthetases.
Topics: Amino Acyl-tRNA Synthetases; Borohydrides; Cyanogen Bromide; Escherichia coli; Isoleucine; Kinetics; Nucleic Acid Conformation; Oxidation-Reduction; RNA Nucleotidyltransferases; RNA, Transfer; Serine; Structure-Activity Relationship; Ultraviolet Rays; Valine | 1974 |
Synthesis of branced-chain aminoacyl-transfer ribonucleid acid synthetases in a Salmonella typhimurium mutant with an altered biosynthetic L-threonine deaminase.
Topics: Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Culture Media; Hydro-Lyases; Isoleucine; Kinetics; Mutation; Pyridoxal Phosphate; Salmonella typhimurium; Threonine; Tritium; Valine | 1974 |
Subcellular localization of isoleucine-valine biosynthetic enzymes in yeast.
Topics: Cell-Free System; Centrifugation, Density Gradient; Hydro-Lyases; Isoleucine; Isomerases; Keto Acids; Mitochondria; Oxidoreductases; Oxo-Acid-Lyases; Pyruvates; Saccharomyces cerevisiae; Spheroplasts; Sucrose; Threonine; Time Factors; Toluene; Valerates; Valine | 1974 |
Isoleucine and valine metabolism in Escherichia coli K-12: detection and measurement of ilv-specific messenger ribonucleic acid.
Topics: Centrifugation, Density Gradient; Coliphages; Culture Media; DNA, Viral; Escherichia coli; Indicators and Reagents; Isoleucine; Mutation; Nucleic Acid Hybridization; RNA, Bacterial; RNA, Messenger; Sucrose; Tritium; Valine; Viral Plaque Assay | 1974 |
Transport of sugars and amino acids in bacteria. XII. Substrate specificities of the branched chain amino acid-binding proteins of Escherichia coli.
Topics: Amino Acids; Animals; Antibodies, Bacterial; Bacterial Proteins; Biological Transport, Active; Cell Fractionation; Cross Reactions; Escherichia coli; Isoleucine; Leucine; Osmosis; Protein Binding; Rabbits; Threonine; Valine | 1974 |
[Effect of growth decrease on the metabolism of fatty acids of Bacillus subtilis var. niger].
Topics: Bacillus subtilis; Chloramphenicol; Culture Media; Fatty Acids; Isoleucine; Temperature; Valine | 1972 |
[Sensitivity of Bacillus cereus T to isoleucine, valine and leucine].
Topics: Amino Acids; Bacillus cereus; Drug Resistance, Microbial; Glucose; Glutamates; Isoleucine; Leucine; Mutation; Valine | 1972 |
Regulation of acetohydroxyacid synthetase in Bacillus subtilis.
Topics: Bacillus subtilis; Enzyme Repression; Feedback; Hydro-Lyases; Isoleucine; Leucine; Oxo-Acid-Lyases; Pyruvates; Threonine; Valine | 1972 |
Production of the placental-type alkaline phosphatase isoennzyme by lung cancer tissue.
Topics: Adenocarcinoma; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cysteine; Edetic Acid; Electrophoresis; Female; Fluorescent Antibody Technique; Hot Temperature; Humans; Immunodiffusion; Immunoelectrophoresis; Isoenzymes; Isoleucine; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Middle Aged; Placenta; Pregnancy; Urea; Valine | 1972 |
Regulation of branched chain amino acid transaminase formation during the growth of Pseudomonas fluorescens UK-1.
Topics: Butyrates; Caproates; Glutamates; Isoleucine; Leucine; Propionates; Pseudomonas; Pseudomonas fluorescens; Transaminases; Valerates; Valine | 1972 |
Formation of 2-oxoisovalerate dehydrogenase in Pseudomonas fluorescens.
Topics: Carbon Isotopes; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Pseudomonas; Pseudomonas fluorescens; Valerates; Valine | 1972 |
[Amino acids in parenteral feeding].
Topics: Alanine; Amino Acids; Arginine; Histidine; Homeostasis; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Nutrition Disorders; Parenteral Nutrition; Phenylalanine; Proline; Protein Conformation; Protein-Energy Malnutrition; Proteins; Threonine; Tryptophan; Valine | 1972 |
[Monovalent repression caused by isoleucine, valine or leucine of the alpha-acetohydroxyacid synthetase of Bacillus cereus T].
Topics: Bacillus cereus; Culture Media; Enzyme Repression; Isoleucine; Leucine; Oxo-Acid-Lyases; Pyruvates; Valine | 1972 |
[Comparative biosynthesis of ramified fatty acids of Bacillus subtilis var niger, in mesosome- or membrane-enriched fractions].
Topics: Acetates; Bacillus subtilis; Carbon Isotopes; Cell Membrane; Fatty Acids; Glycerol; Isoleucine; Organoids; Subcellular Fractions; Valine | 1973 |
Plasma nonessential to essential amino acid ratio in marasmus.
Topics: Amino Acids; Blood Proteins; Child; Child Nutritional Physiological Phenomena; Chromatography, Paper; Densitometry; Glutamine; Glycine; Humans; India; Isoleucine; Kwashiorkor; Leucine; Methionine; Nutrition Disorders; Protein-Energy Malnutrition; Serine; Taurine; Valine | 1973 |
Oxidation of branched chain amino acids by isolated hearts and diaphragms of the rat. The effect of fatty acids, glucose, and pyruvate respiration.
Topics: Amino Acids; Animals; Caprylates; Carbon Dioxide; Carbon Isotopes; Diaphragm; Fatty Acids; Glucose; Heart; Insulin; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Muscles; Myocardium; Oleic Acids; Oxidation-Reduction; Oxygen Consumption; Palmitic Acids; Perfusion; Pyruvates; Rats; Valine | 1972 |
Oxidation of amino acids by diaphragms from fed and fasted rats.
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Diaphragm; Food Deprivation; In Vitro Techniques; Isoleucine; Leucine; Male; Muscles; Oxidation-Reduction; Rats; Time Factors; Valine | 1972 |
Cerebral amino acid uptake in vivo in newborn mice.
Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Dose-Response Relationship, Drug; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Tryptophan; Valine | 1972 |
Sequence of limiting amino acids in gelatin for the growing chick.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Gelatin; Glycine; Histidine; Isoleucine; Lysine; Male; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Valine | 1972 |
Genetic analysis of free plasma amino acids in pure strains of mature chickens.
Topics: Amino Acids; Animals; Autoanalysis; Breeding; Chickens; Female; Genotype; Isoleucine; Male; Molecular Biology; Phenotype; Proline; Serine; Statistics as Topic; Threonine; Valine | 1972 |
[Stability of amino acid infusion solutions. 1. Stability of some amino acids in solutions].
Topics: Amino Acids; Ammonia; Arginine; Chromatography, Paper; Drug Stability; Glycine; Histidine; Hydrogen-Ion Concentration; Injections, Intravenous; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Photometry; Solutions; Sorbitol; Spectrophotometry, Ultraviolet; Sterilization; Threonine; Tryptophan; Valine | 1972 |
Quantitative efficacy of dietary isoleucine and valine for chick growth as influenced by variable quantities of excess dietary leucine.
Topics: Amino Acids; Animals; Chickens; Diet; Isoleucine; Leucine; Male; Methods; Regression Analysis; Valine | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
Variations in the concentrations of free amino acids in the plasma of the dairy cow at parturition.
Topics: Alanine; Amino Acids; Animals; Cattle; Female; Glycine; Isoleucine; Postpartum Period; Pregnancy; Time Factors; Valine | 1972 |
[Effect of a protein-deficient diet on certain biochemical parameters of rat liver cell fractions. 1. Content in free amino acids].
Topics: Amino Acids; Animals; Autoanalysis; Blood Chemical Analysis; Cell Fractionation; Dietary Proteins; Isoleucine; Leucine; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Phenylalanine; Rats; Rats, Inbred Strains; Subcellular Fractions; Tyrosine; Valine | 1972 |
[Consumption of amino acids from casein hydrolysate by nematodes].
Topics: Amino Acids; Animals; Arginine; Ascaridia; Ascaris; Caseins; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Protein Hydrolysates; Valine | 1972 |
Enzymes of the isoleucine-valine pathway in Acinetobacter.
Topics: Alcaligenes; Amino Acids; Cell-Free System; Culture Media; Enzyme Repression; Feedback; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutagens; Mutation; Nitrosoguanidines; Pyruvates; Spectrophotometry; Threonine; Transaminases; Valine | 1972 |
The free amino acid pattern of the intestinal contents of chicks fed raw and heated soybean meal.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Chickens; Coronary Vessels; Cystine; Diet; Dietary Proteins; Electrophoresis, Disc; Glycine max; Hot Temperature; Intestine, Small; Isoleucine; Leucine; Methionine; Nitrogen; Phenylalanine; Plant Proteins; Portal Vein; Solubility; Tyrosine; Ultrafiltration; Valine | 1972 |
Measurement of lipid synthesis in mouse auricular skin cultured in vitro.
Topics: Acetates; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Culture Techniques; Ear, External; Esters; Fatty Acids; Fatty Acids, Nonesterified; Isoleucine; Leucine; Lipids; Mice; Phosphatidylcholines; Phospholipids; Sebaceous Glands; Skin; Sterols; Triglycerides; Valine | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
The electronic g-tensor in cytochrome b5: high resolution proton magnetic resonance studies.
Topics: Alanine; Amino Acid Sequence; Animals; Computers; Cytochromes; Freeze Drying; Iron; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Oxidation-Reduction; Protons; Rabbits; Temperature; Valine | 1972 |
Effect of diets devoid of one essential amino acid on pregnancy in rats maintained by ovarian steroids.
Topics: Amino Acids; Animals; Body Weight; Deficiency Diseases; DNA; Embryonic and Fetal Development; Estrone; Female; Fetal Diseases; Gestational Age; Isoleucine; Leucine; Lysine; Methionine; Placentation; Pregnancy; Pregnancy Complications; Progesterone; Rats; Reproduction; RNA; Tryptophan; Uterus; Valine | 1973 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; Glutamine; Glycine; Histidine; Humans; Ichthyosis; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Muscle Spasticity; Retinal Degeneration; Serine; Syndrome; Valine | 1973 |
Competitive inhibition for amino acid uptake by the indigenous microflora of Upper Klamath Lake.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Canada; Carbon Dioxide; Carbon Isotopes; Culture Media; Fresh Water; Glutamates; Glycine; Isoleucine; Leucine; Micropore Filters; Plankton; Serine; Valine; Water Microbiology | 1973 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
The effect of growth temperatures on the in vivo ribose methylation of Bacillus stearothermophilus transfer RNA.
Topics: Acids; Alkalies; Bacillus; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis, Paper; Hot Temperature; Hydrolysis; Isoleucine; Methylation; Nucleic Acid Denaturation; Nucleotides; Ribonucleases; Ribose; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Temperature; Valine | 1973 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
[Clinical test of the adapted infant's rady-to-eat lactic food Pre-Aptamil].
Topics: Apgar Score; Ascorbic Acid; Birth Weight; Body Weight; Diet Therapy; Female; Food Preservation; Histidine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1973 |
Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: regulatory properties of threonine deaminase.
Topics: Alanine; Amino Acids; Ammonium Sulfate; Ascomycota; Chromatography, Gel; Culture Media; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Protamines; Pyridoxal Phosphate; Stimulation, Chemical; Temperature; Threonine; Valine | 1973 |
Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: properties of acetohydroxy acid synthetase.
Topics: Acetates; Amino Acids; Ammonium Sulfate; Ascomycota; Butanols; Butanones; Carboxy-Lyases; Chromatography, Gel; Feedback; Flavin-Adenine Dinucleotide; Glucose; Glycerol; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactates; Mercury; Oxo-Acid-Lyases; Protamines; Pyruvates; Thiamine Pyrophosphate; Valine | 1973 |
Stereospecificity of blood-brain barrier permeability to amino acids.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Rats; Threonine; Tritium; Tryptophan; Tyrosine; Valine | 1973 |
Bogus branched-chain aminoaciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography; Culture Media; False Positive Reactions; Humans; Isoleucine; Leucine; Valine | 1973 |
Leucine-isoleucine interrelationship in the young pig.
Topics: Animals; Body Weight; Diet; Female; Isoleucine; Leucine; Male; Nutritional Requirements; Swine; Valine | 1973 |
Comparison of acetohydroxy-acid synthetases from two extreme thermophilic bacteria.
Topics: Bacillus; Bacteria; Cell-Free System; Enzyme Repression; Feedback; Flavin-Adenine Dinucleotide; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Lactates; Leucine; Lyases; Magnesium; Mercury; Pyruvates; Species Specificity; Thiamine Pyrophosphate; Valine | 1973 |
Response to dietary therapy in B 12 unresponsive methylmalonic acidemia.
Topics: Acidosis; Agranulocytosis; Blood Glucose; Cephalometry; Child Development; Diet Therapy; Electroencephalography; Female; Growth Disorders; Humans; Infant; Intelligence; Isoleucine; Lymphocytosis; Malonates; Metabolism, Inborn Errors; Methionine; Otitis Media; Threonine; Valine; Vitamin B 12 | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Exchange transport between various amino acids and alanine in isolated intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Ornithine; Phenylalanine; Rats; Sodium; Threonine; Time Factors; Tryptophan; Valine | 1973 |
Essential amino acid levels for starting turkey poults.
Topics: Amino Acids; Animal Feed; Animals; Body Weight; Cystine; Diet; Female; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Nutritional Requirements; Phenylalanine; Threonine; Tryptophan; Turkeys; Valine | 1973 |
Effects of oral alanine administration in fasting obese subjects.
Topics: Administration, Oral; Adult; Alanine; Blood Glucose; Female; Gluconeogenesis; Humans; Hydroxybutyrates; Insulin; Isoleucine; Leucine; Male; Middle Aged; Nitrogen; Obesity; Phosphorus; Potassium; Urea; Uric Acid; Valine | 1973 |
Effect of the branched-chain alpha-keto acids on pyruvate metabolism by homogenates of human brain.
Topics: Brain; Carbon Dioxide; Carbon Isotopes; Cerebral Cortex; Child; Child, Preschool; Humans; Isoleucine; Keto Acids; Leucine; Male; Pyruvates; Valine | 1973 |
[Changes in the free amino acid pool in the abdominal muscle of Penaeus kerathurus during the moulting cycle and during starvation].
Topics: Amino Acids; Animals; Bivalvia; Diet; Histidine; Isoleucine; Leucine; Lysine; Methionine; Muscles; Phenylalanine; Starvation; Threonine; Time Factors; Valine | 1973 |
Plasma free amino acids of swine as influenced by diet protein level, animal age and time of sampling.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Dietary Proteins; Fasting; Female; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Swine; Threonine; Time Factors; Valine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Neoaplectana glaseri: essential amino acids.
Topics: Amino Acids; Animals; Arginine; Coleoptera; Culture Media; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Phenylalanine; Threonine; Tryptophan; Valine | 1973 |
A simplified method for chromatography of Dnp-leucine in the determination of intracellular specific activity of (3H) leucine.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Fluorine; Isoleucine; Leucine; Methods; Mice; Myocardium; Nitrobenzenes; Tritium; Valine | 1973 |
Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of aliphatic amino acids.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Glycine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Valine | 1973 |
Variant maple syrup urine disease in mother and daughter.
Topics: Adult; Biopsy; Carboxy-Lyases; Cells, Cultured; Chromatography, Paper; Dietary Proteins; Female; Fibroblasts; Humans; Infant; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1973 |
Utilization of amino acids by Chromatium sp. strain D.
Topics: Acyltransferases; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chloramphenicol; Chromatium; Chromatography; Glutamates; Glutamine; Isoleucine; Leucine; Light; Stereoisomerism; Transaminases; Valine | 1973 |
Saturation of blood brain barrier transport of amino acids in phenylketonuria.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Humans; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Dietary influences on the activities of enzymes involved in branched-chain amino acid catabolism in the chick.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Carbon Dioxide; Carbon Isotopes; Chickens; Dietary Proteins; Glycine max; Isoleucine; Keto Acids; Ketoglutaric Acids; Ketone Oxidoreductases; Kidney; Leucine; Liver; Male; Muscles; Plant Proteins; Protein Deficiency; Starvation; Structure-Activity Relationship; Transaminases; Valine | 1973 |
Amino acid requirement of the growing rabbits: an estimate of quantitative needs.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Cystine; Female; Glycine; Glycine max; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Plant Proteins; Rabbits; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Plasma amino acid patterns in sheep receiving abomasal infusions of methionine and cystine.
Topics: Abomasum; Amino Acids; Animals; Cystathionine; Cystine; Diet; Dose-Response Relationship, Drug; Glycine; Infusions, Parenteral; Isoleucine; Leucine; Male; Methionine; Serine; Sheep; Taurine; Valine | 1973 |
Proteolysis in homogenates of perfused rat liver: responses to insulin, glucagon and amino acids.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Drug Stability; Glucagon; Hydrogen-Ion Concentration; Insulin; Isoleucine; Kinetics; Leucine; Liver; Lysosomes; Male; Peptide Hydrolases; Perfusion; Rats; Temperature; Time Factors; Valine | 1973 |
The product of the leu-3 cistron as a regulatory element for the production of the leucine biosynthetic enzymes of Neurospora.
Topics: Alcohol Oxidoreductases; Alleles; Culture Media; Dicarboxylic Acids; Enzyme Induction; Genes, Regulator; Genotype; Inositol; Isoleucine; Isomerases; Keto Acids; Leucine; Malates; Mutation; Neurospora; Oxo-Acid-Lyases; Pantothenic Acid; Temperature; Valine | 1973 |
The effect of excess leucine on valine catabolism in the chick.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Chickens; Isoleucine; Leucine; Male; Valine | 1973 |
Differential translation of alpha- and beta-globin messenger in a cell-free system.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Krebs 2; Chromatography, Ion Exchange; Globins; Isoleucine; Osmolar Concentration; Peptide Initiation Factors; Potassium; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Tritium; Valine | 1973 |
Nutritional alteration of the fatty acid composition of a thermophilic Bacillus species.
Topics: Acetates; Bacillus; Butyrates; Chromatography, Gas; Culture Media; Fatty Acids; Hot Temperature; Isoleucine; Isomerism; Leucine; Valerates; Valine | 1973 |
Biosynthesis of saturated and unsaturated fatty acids in the pulmonate landsnail Cepaea nemoralis (L.).
Topics: Acetates; Animals; Carbon Radioisotopes; Chromatography, Gas; Esters; Fatty Acids; Fatty Acids, Unsaturated; In Vitro Techniques; Isoleucine; Mercury; Oxidation-Reduction; Palmitic Acids; Snails; Temperature; Time Factors; Valine | 1973 |
[Repression of isoleucine biosynthesis by an end product of El Tor cholera vibrios].
Topics: Enzyme Repression; Isoleucine; Leucine; Mutation; Pantothenic Acid; Valine; Vibrio cholerae | 1973 |
Hemoglobin heterogeneity in the rabbit: beta-112 isoleucine leads to valine.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Ion Exchange; Genetic Variation; Hemoglobins; Heterozygote; Homozygote; Isoleucine; Male; Peptide Fragments; Rabbits; Trypsin; Valine | 1973 |
Control of leucine metabolism with special reference to branched-chain amino acid transaminase isozymes.
Topics: Alanine; Animals; Carbon Radioisotopes; In Vitro Techniques; Isoenzymes; Isoleucine; Kidney; Leucine; Liver; Male; Mitochondria, Liver; Molecular Biology; Rats; Transaminases; Tyrosine; Valine | 1973 |
Methylmalonic aciduria and vitamin B12 deficiency in the rat.
Topics: Administration, Oral; Animals; Chromatography, Gas; Isoleucine; Male; Malonates; Methionine; Propionates; Rats; Threonine; Valine; Vitamin B 12 Deficiency | 1973 |
Genetic regulatory mechanisms in the fungi.
Topics: Alcohol Oxidoreductases; Alleles; Cell Nucleus; Feedback; Genes; Genes, Regulator; Heterozygote; Isoleucine; Isomerases; Leucine; Molecular Biology; Mutation; Neurospora; Oxo-Acid-Lyases; Phenotype; Valine | 1973 |
Free amino acids and carbohydrates in the cerebrospinal fluid of 305 mentally retarded patients: a screening study.
Topics: Adolescent; Adult; Alanine; Amino Acids; Arginine; Carbohydrates; Child; Child, Preschool; Chromatography, Thin Layer; Cystine; Epilepsy; Female; Glutamates; Glutamine; Humans; Intellectual Disability; Intelligence Tests; Isoleucine; Leucine; Lysine; Male; Metabolism, Inborn Errors; Methionine; Middle Aged; Ornithine; Phenylalanine; Pneumoencephalography; Threonine; Valine | 1973 |
Determination of alpha-keto acids as silylated oximes in urine and serum by combined gas chromatography-mass spectrometry.
Topics: Adult; Animals; Child; Chromatography, Gas; Diet; Evaluation Studies as Topic; Humans; Isoleucine; Keto Acids; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Methods; Oximes; Phenols; Temperature; Valine | 1973 |
[Effect of the set of amino acids contained in casein, extracted soy bean meal, horse beans and wheat gluten on the content of leucine, isoleucine, valine, phenylalanine, tyrosine, glutamic acid, aspartic acid, alanine, glycine and proline in the deprotei
Topics: Alanine; Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Caseins; Chickens; Female; Glutamates; Glutens; Glycine; Glycine max; Isoleucine; Leucine; Phenylalanine; Plant Proteins; Proline; Triticum; Tyrosine; Valine | 1973 |
["Pools" of essential amino acids in the tissues of lysine-deficient adult rats].
Topics: Amino Acids; Animals; Arginine; Deficiency Diseases; Digestive System; Histidine; Humans; Isoleucine; Liver; Lysine; Male; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Valine | 1973 |
Effect of intraperitoneal amino acids on nitrogen balance and plasma amino acids in calves.
Topics: Amino Acids; Animals; Arginine; Cattle; Feces; Glycine; Histidine; Injections, Intraperitoneal; Isoleucine; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Valine | 1974 |
Maple syrup urine disease variant: report on an infant.
Topics: Amino Acids; Ataxia; Body Weight; Carboxy-Lyases; Child Development; Coma; Diet Therapy; Fibroblasts; Growth Disorders; Humans; Infant; Isoleucine; Leucine; Leukocytes; Male; Maple Syrup Urine Disease; Motor Skills; Valine | 1974 |
Plasma concentrations and dietary requirements of leucine, isoleucine and valine: studies with the young chick.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arachis; Body Weight; Chickens; Diet; Isoleucine; Leucine; Male; Nutritional Requirements; Triticum; Valine | 1974 |
An electrophoretically silent polymorphism for the beta chains of rabbit hemoglobin and associated polyribosome patterns.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbon Radioisotopes; Centrifugation, Density Gradient; Genes, Dominant; Genotype; Hemoglobins; Isoleucine; Phenotype; Polymorphism, Genetic; Polyribosomes; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; RNA, Transfer; Spectrophotometry, Ultraviolet; Threonine; Tritium; Valine | 1974 |
[Diazoxide as therapy for idiopathic hypoglycemia in children (author's transl)].
Topics: Catecholamines; Child; Child, Preschool; Cyanosis; Diazoxide; Diet Therapy; Fasting; Female; Fever; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Intellectual Disability; Isoleucine; Leucine; Male; Microcephaly; Pregnancy; Seizures; Valine | 1974 |
Intravenous energy infusion in lambs: effects on nitrogen retention, plasma free amino acids and plasma urea nitrogen.
Topics: Acetates; Amino Acids; Animals; Blood Urea Nitrogen; Butyrates; Energy Metabolism; Fatty Acids, Volatile; Feces; Glucose; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Propionates; Sheep; Valine | 1974 |
Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: regulation of the enzymes involved in isoleucine, valine, and leucine synthesis.
Topics: Alcohol Oxidoreductases; Ascomycota; Cell-Free System; Chromatography, Gel; Culture Media; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoleucine; Isomerases; Keto Acids; Kinetics; Lactates; Leucine; Malates; Oxo-Acid-Lyases; Pyruvates; Spectrophotometry; Spectrophotometry, Ultraviolet; Threonine; Transaminases; Valerates; Valine | 1974 |
Amino acids in the excreta of the tsetse fly, Glossina palpalis.
Topics: Amino Acids; Animals; Arginine; Chromatography, Paper; Cystine; Electrophoresis, Paper; Feces; Glutamates; Histidine; Hydrolysis; Isoleucine; Leucine; Protein Binding; Tsetse Flies; Valine | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Studies on the urinary acidic metabolites excreted by patients with beta-methylcrotonylglycinuria, propionic acidaemia and methylmalonic acidaemia, using gas-liquid chromatography and mass spectrometry.
Topics: Butyrates; Chromatography, Gas; Citrates; Computers; Crotonates; Glycine; Isoleucine; Leucine; Malonates; Mass Spectrometry; Metabolism, Inborn Errors; Oxaloacetates; Propionates; Valine | 1974 |
Filamentous bacterial viruses. IX. Protein synthesis inhibitors and DNA replication.
Topics: Carbon Radioisotopes; Chloramphenicol; Chromatography, Thin Layer; Coliphages; DNA Replication; DNA Viruses; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Isoleucine; Mutation; Phosphorus Radioisotopes; Thymidine; Time Factors; Tritium; Uridine; Valine; Viral Proteins | 1974 |
Role of the leu-3 cistron in the regulation of the synthesis of isoleucine and valine biosynthetic enzymes of Neurospora.
Topics: Alcohol Oxidoreductases; Cell-Free System; Dicarboxylic Acids; Enzyme Repression; Feedback; Genes; Hydro-Lyases; Isoleucine; Leucine; Mutation; Neurospora; Oxo-Acid-Lyases; Threonine; Valerates; Valine | 1974 |
[Analysis of amino acids of blood serum by the method of ion exchange chromatography].
Topics: Adult; Amino Acids; Chromatography, Ion Exchange; Female; Glutamates; Humans; Isoleucine; Male; Middle Aged; Valine | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Quantitative evaluation of nonspecific nitrogen sources for the growing chick.
Topics: Amino Acids, Essential; Animals; Arginine; Body Composition; Body Water; Body Weight; Chickens; Citrates; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Male; Nitrogen; Proline; Quaternary Ammonium Compounds; Urea; Valine | 1974 |
Characteristics of the inhibition of ornithine-delta-aminotransferase by branched-chain amino acids.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Mitochondria; Ornithine; Rats; Transaminases; Valine | 1974 |
Substitution of five essential amino acids by their alpha-keto analogues in the diet of rats.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Calcium; Diet; Glutamates; Isoleucine; Keto Acids; Kidney; Leucine; Liver; Male; Methionine; Neomycin; Organ Size; Phenylalanine; Rats; Sodium; Structure-Activity Relationship; Urea; Valine | 1974 |
Valine-sensitive nonketotic hyperglycinemia. Case report.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Benzoates; Brain Diseases; Brain Stem; Carbon Dioxide; Carbon Radioisotopes; Chromatography; Coma; Diet Therapy; Drug Hypersensitivity; Electroencephalography; Female; Glycine; Humans; Hydroxyproline; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Isoleucine; Valine | 1974 |
Maple syrup urine disease: coenzyme function and prenatal monitoring.
Topics: Adult; Amino Acids; Amniotic Fluid; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Coenzyme A; Decarboxylation; Fasting; Female; Fibroblasts; Genotype; Heterozygote; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Maternal-Fetal Exchange; Pregnancy; Prenatal Diagnosis; Radioimmunoassay; Valine | 1974 |
sRNA specificity for codon recognition as studied by the ribosomal binding technique.
Topics: Alanine; Arginine; Chromatography; Countercurrent Distribution; Escherichia coli; Genetic Code; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Serine; Tryptophan; Valine; Yeasts | 1966 |
Threonine deaminase from Salmonella typhimurium. II. The subunit structure.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Centrifugation, Zonal; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Hydro-Lyases; Isoleucine; Molecular Weight; Optical Rotatory Dispersion; Peptides; Protein Hydrolysates; Salmonella typhimurium; Valine | 1968 |
Isoleucine and valine metabolism of Escherichia coli. XIV. Effect of thiaisoleucine.
Topics: Carbon Isotopes; Escherichia coli; Hydro-Lyases; Isoleucine; Threonine; Transaminases; Valine | 1968 |
Isoleucine and valine metabolism of Escherichia coli. XVI. Pattern of multivalent repression in strain K-12.
Topics: Enzyme Repression; Escherichia coli; Hydro-Lyases; Isoleucine; Ligases; Molecular Biology; Oxidoreductases; Threonine; Transaminases; Valine | 1968 |
Diauxie used as a microbiological assay for L-isoleucine or L-valine in Escherichia coli.
Topics: Biological Assay; Escherichia coli; Glucose; Isoleucine; Lactose; Valine | 1968 |
Carbon dioxide as a growth factor for mutants of Escherichia coli.
Topics: Arginine; Carbon Dioxide; Conjugation, Genetic; Escherichia coli; Genetics, Microbial; Histidine; Isoleucine; Methionine; Mutagens; Mutation; Neurospora; Nitroso Compounds; Penicillins; Purines; Pyrimidines; Succinates; Ultraviolet Rays; Valine | 1968 |
Transport of sugars and amino acids in bacteria. I. Purification and specificity of the galactose- and leucine-binding proteins.
Topics: Bacterial Proteins; Biological Transport, Active; Carbon Isotopes; Chemical Precipitation; Chromatography, Ion Exchange; Dialysis; Electrophoresis, Disc; Escherichia coli; Galactose; Genetics, Microbial; Glucose; Isoleucine; Leucine; Mutation; Osmosis; Phosphotransferases; Protein Binding; Valine | 1968 |
[Effect of chloramphenicol on the incorporation of labelled amino acids in cell-free system obtained from E. coli].
Topics: Amino Acids; Arginine; Carbon Isotopes; Cell-Free System; Chloramphenicol; Escherichia coli; Histocytochemistry; Isoleucine; Leucine; Lysine; Phenylalanine; Threonine; Time Factors; Valine | 1967 |
Heterogeneity of transfer ribonucleic acids from yellow lupin seeds.
Topics: Carbon Isotopes; Cell-Free System; Chromatography; Countercurrent Distribution; Escherichia coli; Genetic Code; Hydroxyapatites; Isoleucine; Leucine; Polynucleotides; RNA, Bacterial; RNA, Transfer; Seeds; Valine | 1968 |
A study of the toxicity to several cyclopentylamino acid analogs.
Topics: Amino Acids; Animals; Body Weight; Cyclopentanes; Escherichia coli; Isoleucine; Leucine; Male; Mice; Valine | 1968 |
Isoleucine-valine requiring mutants of Salmonella typhimurium. II. Strains deficient in dihydroxyacid dehydratase activity.
Topics: Chromosome Mapping; Hydro-Lyases; Isoleucine; Isomerases; Mutation; Recombination, Genetic; Salmonella typhimurium; Transaminases; Transduction, Genetic; Valine | 1968 |
Amino acid control over RNA synthesis: a re-evaluation.
Topics: Amino Acids; Bacterial Proteins; Escherichia coli; Guanine; Isoleucine; Ligases; Nucleosides; RNA, Bacterial; RNA, Transfer; Tritium; Valine | 1968 |
Control of isoleucine, valine and leucine biosynthesis. V. Dual effect of alpha-aminobutyric acid on repression and endproduct inhibition in Escherichia coli.
Topics: Aminobutyrates; Carbon Isotopes; Enzyme Repression; Escherichia coli; Hydro-Lyases; Isoleucine; Leucine; Ligases; Pyruvates; RNA, Transfer; Valine | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Repression by glucose of acetohydroxy acid synthetase in Escherichia coli B.
Topics: Enzyme Repression; Escherichia coli; Glucose; Glycerol; Hydrogen-Ion Concentration; Isoleucine; Lactates; Leucine; Ligases; Pantothenic Acid; Valine | 1969 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Regulation of branched-chain amino acid biosynthesis in Salmonella typhimurium: isolation of regulatory mutants.
Topics: Feedback; Genes, Regulator; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Ligases; Models, Theoretical; Molecular Biology; Mutation; Operon; Oxidoreductases; Salmonella typhimurium; Valine | 1969 |
Antipolarity in the ilv operon of Escherichia coli K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Escherichia coli; Genes; Genetic Complementation Test; Genetics, Microbial; Hydro-Lyases; Isoleucine; Molecular Biology; Mutation; Operon; Threonine; Transaminases; Transduction, Genetic; Valine | 1969 |
Control of isoleucine, valine, and leucine biosynthesis. VI. Effect of 5',5',5'-trifluoroleucine on repression in Salmonella typhimurium.
Topics: Acyltransferases; Alcohol Oxidoreductases; Amidohydrolases; Amino Acids; Bacterial Proteins; Enzyme Repression; Genetics, Microbial; Hydro-Lyases; Isoleucine; Isomerases; Leucine; Molecular Biology; Mutation; Ornithine Carbamoyltransferase; RNA, Transfer; Salmonella typhimurium; Threonine; Valine | 1969 |
Formation of valyl- and isoleucyl-sRNA synthetases in a valine-requiring mutant of Escherichia coli.
Topics: Escherichia coli; Isoleucine; Leucine; Ligases; Valine | 1969 |
Formation of aminoacyl-sRNA synthetases during growth phases of Escherichia coli.
Topics: Adenosine Triphosphate; Escherichia coli; Isoleucine; Leucine; Ligases; Methionine; Phenylalanine; Tryptophan; Tyrosine; Ultrasonics; Valine | 1969 |
Studies on valyl-tRNA synthetase and tRNA from Escherichia coli. I. Purification and properties of the enzyme from normal Escherichia coli strains.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Binding Sites; Escherichia coli; Immune Sera; Isoleucine; Ligases; Molecular Weight; RNA, Bacterial; RNA, Transfer; Ultracentrifugation; Valine | 1969 |
Specificity of aminoacyl transfer ribonucleic acid synthetases from Escherichia coli K12.
Topics: Adenosine Triphosphate; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Genetic Code; Isoleucine; Kinetics; Leucine; Ligases; Methionine; Phosphorus Isotopes; RNA, Transfer; Threonine; Valine | 1969 |
Chain initiation during polypeptide synthesis in cell-free bacterial systems programmed with plant viral messengers. 3. A comparison with the phage RNA-directed system.
Topics: Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Escherichia coli; Filtration; Formates; Isoleucine; Kinetics; Methionine; Peptide Biosynthesis; Phenylalanine; Phosphorus Isotopes; Plant Viruses; Ribosomes; RNA, Messenger; RNA, Transfer; RNA, Viral; Transferases; Tritium; Valine | 1969 |
The metabolism of valine and isoleucine in Escherichia coli. XVII. The role of induction in the derepression of acetohydroxy acid isomeroreductase.
Topics: Alcohol Oxidoreductases; Enterobacter; Enzyme Induction; Enzyme Repression; Escherichia coli; Hydro-Lyases; Hydroxybutyrates; Isoleucine; Lactates; Lyases; Salmonella typhimurium; Threonine; Valine | 1969 |
Cobaltous ion effect on diauxie.
Topics: Cobalt; Escherichia coli; Glucose; Histidine; Isoleucine; Lactose; Threonine; Valine | 1969 |
Purification of a leucine-specific binding protein from Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Biological Transport; Carbon Isotopes; Chromatography, DEAE-Cellulose; Crystallization; Depression, Chemical; Electrophoresis, Disc; Escherichia coli; Filtration; Isoleucine; Kinetics; Leucine; Molecular Weight; Osmosis; Protein Binding; Valine | 1970 |
Polyamines and protein synthesis. V. Effect of salt solutions on aminoacyl transfer RNA formation.
Topics: Acetates; Amino Acids; Ammonium Chloride; Carbon Isotopes; Chlorides; Chromatography, Gel; Escherichia coli; Isoleucine; Leucine; Ligases; Lithium; Magnesium; Potassium Chloride; Protein Biosynthesis; RNA, Bacterial; RNA, Transfer; Sodium Chloride; Spermine; Valine | 1970 |
Control of isoleucine, valine and leucine biosynthesis. 8. Mechanism of growth inhibition by leucine in relaxed and stringent strains of Escherichia coli K-12.
Topics: Bacterial Proteins; Carbon Isotopes; Chromatography; Culture Media; Enzyme Repression; Escherichia coli; Hydro-Lyases; Isoleucine; Leucine; Lyases; Molecular Biology; Mutation; Phenylalanine; RNA, Bacterial; Salmonella typhimurium; Threonine; Time Factors; Uracil; Valine | 1970 |
A Salmonella typhimurium locus involved in the regulation of isoleucine, valine and leucine biosynthesis.
Topics: Alleles; Chromosome Mapping; Crossing Over, Genetic; Enzyme Repression; Genetic Linkage; Isoleucine; Leucine; Molecular Biology; Mutation; Operon; Recombination, Genetic; Salmonella typhimurium; Transduction, Genetic; Valine | 1969 |
[Acetoin formation by Lactobacillus plantarum dependent on thiamine, lipoic acid, L-valine, and L-isoleucine].
Topics: Butanones; Culture Media; Fermentation; Glucose; Isoleucine; Lactobacillus; Photometry; Pyruvates; Thiamine; Thioctic Acid; Valine | 1970 |
Growth of Escherichia coli cells in the presence of cysteine on sulphate-deficient media.
Topics: Amino Acids; Culture Media; Cysteamine; Cysteine; Depression, Chemical; Escherichia coli; Isoleucine; Leucine; Spectrophotometry; Sulfates; Threonine; Valine | 1969 |
Presence of one polypeptide chain in valyl and isoleucyl tRNA synthetases from Escherichia coli.
Topics: Adenosine Triphosphate; Binding Sites; Detergents; Dialysis; Electrophoresis; Escherichia coli; Isoleucine; Ligases; Molecular Weight; Peptides; Protein Denaturation; RNA, Transfer; Sulfuric Acids; Urea; Valine | 1970 |
[Inhibition of Escherichia coli K10 growth by pration of valine, leucine and isoleucine].
Topics: Bacterial Proteins; Culture Media; Enzyme Repression; Escherichia coli; Genetics, Microbial; Isoleucine; Leucine; Mutation; Valine | 1969 |
The primary structure of transfer ribonucleic acid.
Topics: Alanine; Aspartic Acid; Cryptococcus; Escherichia coli; Genetic Code; Isoleucine; Leucine; Methionine; Methylation; Nucleotides; Phenylalanine; RNA, Transfer; Saccharomyces; Serine; Tryptophan; Tyrosine; Valine | 1971 |
The effect of branched chain amino acids on the synthesis of isoleucine from threonine and pyruvate in crude extracts from Escherichia coli.
Topics: Alanine; Aspartic Acid; Chromatography, Thin Layer; Escherichia coli; Isoleucine; Leucine; Pyruvates; Serine; Threonine; Tissue Extracts; Valine | 1970 |
Induction of closely linked multiple mutations by nitrosoguanidine.
Topics: Arabinose; Chromosome Mapping; Escherichia coli; Genetics, Microbial; Guanidines; Histidine; Isoleucine; Leucine; Models, Biological; Mutagens; Mutation; Nitroso Compounds; Phenylalanine; Thymine; Tritium; Valine | 1971 |
Mutants of Salmonella typhimurium with an altered leucyl-transfer ribonucleic acid synthetase.
Topics: Adenosine Triphosphate; Bacteriological Techniques; Carbon Isotopes; Chromosome Mapping; Conjugation, Genetic; Crosses, Genetic; Culture Media; Drug Resistance, Microbial; Enzyme Repression; Fluorine; Hydro-Lyases; Isoleucine; Leucine; Ligases; Magnesium; Models, Chemical; Mutation; RNA, Transfer; Salmonella typhimurium; Tritium; Valine | 1971 |
Increase in isoleucine accumulation by alpha-aminobutyric acid-resistant mutants of Serratia marcescens.
Topics: Aminobutyrates; Biological Assay; Cell-Free System; Culture Media; Drug Resistance, Microbial; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Leuconostoc; Lyases; Mutation; Serratia marcescens; Stereoisomerism; Threonine; Valine | 1971 |
The reactivity of the N-terminal isoleucine of alpha-chymotrypsin as a function of ionic strength.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cold Temperature; Deamination; Dipeptides; Hydrogen-Ion Concentration; Ions; Isoleucine; Kinetics; Nitrites; Osmolar Concentration; Pepsin A; Valine; X-Ray Diffraction | 1971 |
Conformation of synthetic polypeptide monolayers.
Topics: Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Fluoroacetates; Isoleucine; Leucine; Membranes, Artificial; Peptides; Valine | 1971 |
A rapid determination of dihydroxyacid dehydratase activity in microbial cell suspensions.
Topics: Aerobiosis; Anaerobiosis; Cell Membrane Permeability; Cell-Free System; Chromatography, Thin Layer; Culture Media; Detergents; Enterobacter; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Klebsiella; Magnesium; Methods; Pseudomonas; Quaternary Ammonium Compounds; Time Factors; Valerates; Valine | 1971 |
Similar effects by valine and isoleucine on threonine deaminase.
Topics: Binding Sites; Drug Stability; Enzyme Activation; Escherichia coli; Hydro-Lyases; Isoleucine; Kinetics; Threonine; Toluene; Valine | 1970 |
Isoleucine-valine requiring mutants of Salmonella typhimurium. 3. Valine-sensitive strains.
Topics: Chromosome Mapping; Enzyme Induction; Genes; Growth; Hydro-Lyases; Isoleucine; Ligases; Lyases; Methionine; Molecular Biology; Oxidoreductases; Pyruvates; Salmonella typhimurium; Threonine; Transaminases; Transduction, Genetic; Valine | 1971 |
Transport of sugars and amino acids in bacteria. IV. Regulation of valine transport activity by valine and cysteine.
Topics: Bacterial Proteins; Biological Transport; Cysteine; Depression, Chemical; Escherichia coli; Isoleucine; Proline; Pyruvates; RNA, Bacterial; Tritium; Uridine; Valine | 1971 |
Isoleucine hydroxamate, an isoleucine antagonist.
Topics: Chemical Phenomena; Chemistry; Culture Media; Densitometry; Hydro-Lyases; Hydroxamic Acids; Isoleucine; Ligases; Serratia marcescens; Threonine; Transaminases; Valine | 1971 |
Multivalent repression and genetic depression of isoleucine-valine biosynthetic enzymes in Serratia marcescens.
Topics: Cell-Free System; Culture Media; Enzyme Activation; Enzyme Repression; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Pantothenic Acid; Pyruvates; Serratia marcescens; Threonine; Transaminases; Valine | 1971 |
The mechanism of amino acid control of guanylate and adenylate biosynthesis.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Aspartic Acid; Carbon Isotopes; Escherichia coli; Feedback; Genes; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Isoleucine; Ligases; Mutation; Nucleotides; Operon; Oxidoreductases; Species Specificity; Stimulation, Chemical; Uracil; Valine | 1971 |
Recombination involving the ilv cluster of Salmonella typhimurium-Salmonella montevideo hybrids.
Topics: Chromosomes, Bacterial; Crosses, Genetic; Genetics, Microbial; Hybridization, Genetic; Isoleucine; Recombination, Genetic; Salmonella; Salmonella typhimurium; Transduction, Genetic; Valine | 1971 |
Chain initiation during polypeptide synthesis in cell-free bacterial systems programmed with a plant viral messenger. Initiation with N-acetylated aminoacyl-tRNAs on adjacent codons.
Topics: Acylation; Amino Acids; Binding Sites; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Coliphages; Electrophoresis, Paper; Escherichia coli; Genetic Code; Genetics, Microbial; Guanosine Triphosphate; Isoleucine; Magnesium; Medicago sativa; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Peptides; Phenylalanine; Plant Viruses; Ribosomes; RNA, Messenger; RNA, Transfer; RNA, Viral; Tritium; Valine | 1971 |
On the process of cellular division in Escherichia coli. I. Asymmetrical cell division and production of deoxyribonucleic acid-less bacteria.
Topics: Autoradiography; Cell Division; Cell Nucleus; Chromosomes; Clone Cells; Coliphages; Crosses, Genetic; Culture Media; DNA Nucleotidyltransferases; DNA Replication; DNA, Bacterial; Escherichia coli; Genetics, Microbial; Glucose; Histocytochemistry; Isoleucine; Methods; Microscopy, Electron; Microscopy, Phase-Contrast; Mutation; Oxygen Consumption; RNA Nucleotidyltransferases; RNA, Bacterial; Thymidine; Thymine; Tritium; Valine | 1968 |
Regulation of synthesis of the aminoacyl-transfer ribonucleic acid synthetases for the branched-chain amino acids of Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Cesium; Chlorides; Culture Media; Enzyme Repression; Escherichia coli; Genetics, Microbial; Isoleucine; Leucine; Salmonella typhimurium; Spectrophotometry; Stereoisomerism; Valine | 1971 |
Selective inactivation of amino acid acceptor and ribosome-binding activities of Escherichia coli tRNA by modification with cyanogen bromide.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Arginine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanogen Bromide; Escherichia coli; Glutamates; Glutamine; Glycine; Guanine Nucleotides; Histidine; Isoleucine; Kinetics; Lysine; Methylamines; Nucleic Acid Conformation; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Structure-Activity Relationship; Thiouracil; Tyrosine; Uracil Nucleotides; Uridine; Valine | 1971 |
Isolation and partial characterization of temperature-sensitive Escherichia coli mutants with altered leucyl- and seryl-transfer ribonucleic acid synthetases.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Cell-Free System; Chromosome Mapping; Crosses, Genetic; Culture Media; Enzyme Repression; Escherichia coli; Genetics, Microbial; Immune Sera; Isoleucine; Leucine; Mutagens; Mutation; Nitrosoguanidines; Serine; Temperature; Transduction, Genetic; Valine | 1971 |
Evidence that the majority of leucine transfer ribonucleic acid is not involved in repression in Salmonella typhimurium.
Topics: Amino Acyl-tRNA Synthetases; Culture Media; Enzyme Repression; Fluorine; Genetics, Microbial; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Pyruvates; RNA, Bacterial; RNA, Transfer; Salmonella typhimurium; Threonine; Transfer RNA Aminoacylation; Valine | 1971 |
Chromatographic fractionation of transfer RNA on the macroreticular polystyrene ion-exchange resin amberlyst A-21.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Isoleucine; Liver; Polystyrenes; Rats; RNA, Transfer; Saccharomyces cerevisiae; Temperature; Valine | 1971 |
Involvement of threonine deaminase in multivalent repression of the isoleucine-valine pathway in Saccharomyces cerevisiae.
Topics: Culture Media; Enzyme Repression; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Pyruvates; Saccharomyces; Saccharomyces cerevisiae; Threonine; Valine | 1971 |
Mechanism of the growth inhibitory effect of cysteine on Escherichia coli.
Topics: Carbon Isotopes; Cell Membrane; Culture Media; Cysteamine; Cysteine; Escherichia coli; Galactosidases; Isoleucine; Leucine; Protein Binding; RNA; Sulfates; Sulfur Isotopes; Threonine; Uracil; Valine | 1971 |
Escherichia coli K-12 mutants altered in the transport of branched-chain amino acids.
Topics: Amino Acids; Biological Transport, Active; Carbon Isotopes; Chromosome Mapping; Culture Media; Dipeptides; Escherichia coli; Hydro-Lyases; Isoleucine; Leucine; Mutagens; Mutation; Nitrosoguanidines; Threonine; Transduction, Genetic; Ultraviolet Rays; Valine | 1971 |
Reaction velocity response of the Escherichia coli biosynthetic L-threonine deaminase to rapid changes in substrate and modifier ligand concentrations.
Topics: Allosteric Regulation; Ammonium Sulfate; Binding Sites; Calcium Phosphates; Catalysis; Chemical Precipitation; Chromatography; Electrophoresis, Disc; Enzyme Activation; Escherichia coli; Hot Temperature; Hydro-Lyases; Isoleucine; Kinetics; Threonine; Time; Valine | 1971 |
Properties of isoleucine hydroxamate-resistant mutants of Serratia marcescens.
Topics: Culture Media; Enzyme Repression; Feedback; Glycolates; Hydro-Lyases; Hydroxamic Acids; Isoleucine; Ligases; Mutation; Serratia marcescens; Threonine; Transaminases; Valine | 1971 |
Studies on acetohydroxy acid synthetase in Pseudomonas aeruginosa.
Topics: In Vitro Techniques; Isoleucine; Ligases; Pseudomonas aeruginosa; Valine | 1965 |
Biosynthesis of branched-chain fatty acids. IV. Factors affecting relative abundance of fatty acids produced by Bacillus subtilis.
Topics: Asparagine; Bacillus subtilis; Biotin; Chromatography, Gas; Culture Media; Fatty Acids; Isoleucine; Leucine; Valine | 1966 |
Amino acid control of ribonucleic acid excretion in Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Cysteine; Cystine; Hydroxyproline; Isoleucine; RNA, Bacterial; Threonine; Valine | 1966 |
The metabolism of the amino acids of Escherichia coli and other bacteria by the rumen ciliate Entodinium caudatum.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Ciliophora; Cysteine; Escherichia coli; Glutamates; Isoleucine; Leucine; Rumen; Serratia marcescens; Valine | 1967 |
Studies on the specificity of Bacillus subtilis neutral protease with synthetic substrates.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Catalysis; Histidine; Isoleucine; Kinetics; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Serine; Threonine; Valine | 1967 |
The NH2-terminal residues of Bacillus subtilis proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Fluorine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Nitrobenzenes; Proteins; Ribosomes; Serine; Species Specificity; Threonine; Tritium; Valine | 1968 |
Transaminases of branched chain amino acids. IV. Purification and properties of two enzymes from rat liver.
Topics: Animals; Chromatography; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Isoleucine; Ketoglutaric Acids; Kinetics; Leucine; Liver; Mercaptoethanol; Myocardium; Oxaloacetates; Pyridoxal Phosphate; Pyruvates; Rats; Spectrophotometry; Swine; Transaminases; Valine | 1968 |
Species differences of serum amino acid beta-napthylamidases.
Topics: Alanine; Amides; Amino Acids; Aminopeptidases; Animals; Arginine; Chickens; Cyprinidae; Dipeptides; Dogs; Female; Glutamine; Glycine; Haplorhini; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Naphthalenes; Phenylalanine; Proline; Rats; Serine; Species Specificity; Valine | 1968 |
[Reamination and reductive amination in virulent strains of tuberculosis mycobacteria].
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Ammonium Chloride; Aspartic Acid; Culture Media; Genetics, Microbial; Isoleucine; Keto Acids; Ketoglutaric Acids; Leucine; Mycobacterium tuberculosis; Oxaloacetates; Pyruvates; Transaminases; Valine | 1966 |
Studies on the intracellular localization of tetracycline in bacteria.
Topics: Bacillus cereus; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Paper; Culture Media; Densitometry; Drug Resistance, Microbial; Escherichia coli; Fluorometry; Hydrogen-Ion Concentration; Isoleucine; Leucine; Nucleotides; Peptide Biosynthesis; Phenylalanine; Ribosomes; Spectrophotometry; Tetracycline; Tritium; Tyrosine; Uracil Nucleotides; Valine | 1968 |
Bacillus cereus spore germination:absolute requirement for an amine acid.
Topics: Alanine; Amino Acids; Aminobutyrates; Bacillus cereus; Culture Media; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Nucleosides; Purines; Serine; Spores; Stereoisomerism; Valine | 1968 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Catabolite repression and feedback inhibition of protease in Streptococcus faecalis var. liquefaciens.
Topics: Amino Acids; Dipeptides; Enterococcus faecalis; Enzyme Repression; Feedback; Galactosidases; Isoleucine; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Tryptophan; Valine | 1968 |
Synthesis of valine and isoleucine in primitive earth conditions.
Topics: Acetone; Cyanides; Isoleucine; Ketones; Nitriles; Polymers; Valine | 1969 |
Leaf epicuticular waxes.
Topics: Aldehydes; Alkanes; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Isoleucine; Microscopy, Electron; Mycobacterium tuberculosis; Plants; Surface Properties; Valine; Waxes | 1967 |
The multiple forms of mushroom tyrosinase. Structural studies on the isozymes.
Topics: Amino Acids; Basidiomycota; Carboxypeptidases; Catechol Oxidase; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Ion Exchange; Copper; Electrophoresis; Isoenzymes; Isoleucine; Molecular Weight; Peptides; Trypsin; Ultracentrifugation; Valine | 1969 |
Transaminase of branched chain amino acids. VI. Purification and properties of the hog brain enzyme.
Topics: Animals; Brain; Cellulose; Chromatography; Electrophoresis; Immune Sera; Immunodiffusion; Isoleucine; Ketoglutaric Acids; Kidney; Kinetics; Leucine; Liver; Male; Molecular Weight; Myocardium; Proteins; Pyridoxal Phosphate; Swine; Time Factors; Transaminases; Ultracentrifugation; Valine | 1969 |
[Properties of threonine deaminase from wild type and a valine sensitive mutant of Bacillus subtilis].
Topics: Amino Acids; Bacillus subtilis; Binding Sites; Feedback; Genes; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Mutation; Threonine; Valine | 1969 |
Effect of furanomycin on the synthesis of isoleucyl-tRNA.
Topics: Acetates; Animals; Anti-Bacterial Agents; Bacillus subtilis; Cell-Free System; Depression, Chemical; Escherichia coli; Furans; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rats; RNA, Bacterial; RNA, Transfer; Streptomyces; Valine | 1969 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Inhibition of the amino acid induced initiation of germination of bacterial spores by chlorocresol.
Topics: Alanine; Bacillus subtilis; Cresols; Cysteine; Endopeptidases; Isoleucine; Leucine; Spores; Valine | 1970 |
[Regulatory deficiencies in mutants of Hydrogenomonas H 16 resistant to trifluoroleucine].
Topics: Butanones; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Drug Resistance, Microbial; Escherichia coli; Fluorine; Fluorometry; Isoenzymes; Isoleucine; Lactates; Leucine; Ligases; Micrococcus; Mutation; Pseudomonas; Pseudomonas aeruginosa; Valine | 1969 |
[The alpha-isopropylmalate synthetase of Hydrogenomonas H 16].
Topics: Acetates; Acyltransferases; Carbon Isotopes; Catalysis; Chromatography, Paper; Coenzyme A; Culture Media; Dicarboxylic Acids; Fluorometry; Hydrogen-Ion Concentration; Isoenzymes; Isoleucine; Keto Acids; Leucine; Mutation; Pseudomonas; Valerates; Valine | 1969 |
Threonine deaminase from Bacillus subtilis. II. The steady state kinetic properties.
Topics: Bacillus subtilis; Binding Sites; Carbon Isotopes; Colorimetry; Enzyme Activation; Hydro-Lyases; Isoleucine; Kinetics; L-Lactate Dehydrogenase; Mathematics; Methods; Spectrophotometry; Threonine; Time Factors; Ultraviolet Rays; Valine | 1970 |
Threonine deaminase from Bacillus subtilis. 3. Pre-steady state kinetic properties.
Topics: Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Enzyme Activation; Hydro-Lyases; Isoleucine; Kinetics; Mathematics; Models, Biological; Models, Chemical; Spectrophotometry; Threonine; Time Factors; Ultraviolet Rays; Valine | 1970 |
Purification and partial characterization of the branched chain amino acid transaminase of Pseudomonas aeruginosa.
Topics: Aldehydes; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Glutarates; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Methods; Molecular Weight; Phenylalanine; Picolines; Pseudomonas aeruginosa; Sulfates; Transaminases; Valine | 1970 |
Deficiency of dihydroxy acid dehydratase in the mitochondria of the iv-I mutants of Neurospora crassa.
Topics: Centrifugation; Culture Media; Hydro-Lyases; Immunodiffusion; Isoleucine; Mitochondria; Mutation; Neurospora; Solubility; Valine | 1970 |
[The biosynthesis of isoleucine and valine in Hydrogenomonas H 16].
Topics: Cell-Free System; Culture Media; Genetics, Microbial; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Mutation; Pseudomonas; Threonine; Valine | 1969 |
[Enrichment and isolation of auxotrophic mutants of Hydrogenomonas H 16].
Topics: Adenine; Agar; Colistin; Fructose; Genetics, Microbial; Guanidines; Hydro-Lyases; Isoleucine; Leucine; Lyases; Mutation; Nitrites; Nitroso Compounds; Pseudomonas; Ultraviolet Rays; Valine | 1969 |
Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37Rv. II. Purification and properties of acetohydroxy acid isomerase.
Topics: Acrylates; Agar; Ascorbic Acid; Benzoates; Chromatography, DEAE-Cellulose; Chromatography, Paper; Drug Stability; Electrophoresis; Electrophoresis, Disc; Gels; Hydrogen-Ion Concentration; Isoleucine; Isomerases; Keto Acids; Kinetics; Lactates; Mercaptoethanol; Mercury; Mycobacterium tuberculosis; Organometallic Compounds; Sulfates; Valerates; Valine | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
Mutants of Pseudomonas aeruginosa strain 1 with unusual acetohydroxy acid synthetase enzymes.
Topics: Cell-Free System; Chromosome Mapping; Flavin-Adenine Dinucleotide; Isoleucine; Lyases; Mutation; Pseudomonas aeruginosa; Pyruvates; Thiamine Pyrophosphate; Valine | 1970 |
Regulation of isoleucine-valine biosynthesis in Pseudomonas aeruginosa. I. Characterisation and mapping of mutants.
Topics: Chromosome Mapping; Conjugation, Genetic; Genetic Linkage; Isoleucine; Molecular Biology; Operon; Pseudomonas aeruginosa; Transduction, Genetic; Valine | 1969 |
Regulation of isoleucine-valine biosynthesis in Pseudomonas aeruginosa. II. Regulation of enzyme activity and synthesis.
Topics: Binding Sites; Chromatography, Gel; Enzyme Repression; Feedback; Hydro-Lyases; Isoleucine; Kinetics; Ligases; Pseudomonas aeruginosa; Valine | 1969 |
The isolation of gamma-glutamyl peptides from monkey brain.
Topics: Alanine; Animals; Brain Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Glutamates; Glutamine; Glycine; Haplorhini; Isoleucine; Peptides; Serine; Species Specificity; Valine | 1970 |
[Threonine deaminease from Arthrobacter strain 23].
Topics: Alanine; Aminobutyrates; Aminoisobutyric Acids; Arthrobacter; Binding Sites; Bromides; Carbohydrates; Cell-Free System; Chemical Precipitation; Culture Media; Edetic Acid; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sulfates; Threonine; Ultracentrifugation; Valine; Vibration | 1971 |
[Biosynthesis of linear or branched fatty acids, during sporulation of Bacillus subtilis var. Niger. Study by gas radiochromatography].
Topics: Acetates; Bacillus subtilis; Carbon Isotopes; Chromatography, Gas; Fatty Acids; Isoleucine; Spores; Valine | 1971 |
[Branched chain amino acid transaminase isozymes in various cancer cells and in the process of oncogenesis].
Topics: Animals; Antibodies; Brain; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Immunodiffusion; Isoenzymes; Isoleucine; Leucine; Liver Neoplasms; Male; Neoplasms, Experimental; Neutralization Tests; Rats; Sarcoma, Yoshida; Transaminases; Ultracentrifugation; Valine | 1971 |
[Molecular-biological study on L-penicillamine].
Topics: Animals; Bacillus subtilis; Body Weight; Colorimetry; Escherichia coli; In Vitro Techniques; Isoleucine; Leucine; Liver; Male; Penicillamine; Proteins; Radiometry; Rats; RNA, Transfer; Tritium; Valine | 1971 |
Fatty acid-requiring mutant of bacillus subtilis defective in branched chain alpha-keto acid dehydrogenase.
Topics: Bacillus subtilis; Butyrates; Caproates; Carbon Isotopes; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Gas; Fatty Acids; Fluorine; Genetics, Microbial; Isoleucine; Keto Acids; Leucine; Mass Spectrometry; Mutation; Nitriles; Oxidoreductases; Valerates; Valine | 1971 |
[Mechanism of regulation of alpha-acetohydroxyacid-synthetase in Bacillus cereus T].
Topics: Bacillus cereus; Hydrogen-Ion Concentration; In Vitro Techniques; Isoleucine; Lactates; Leucine; Ligases; Pyruvates; Valine | 1971 |
Studies in valine biosynthesis. IX. The enzymes in photosynthetic and autotrophic bacteria.
Topics: Aerobiosis; Alanine; Alcohols; Anaerobiosis; Bacteria; Carboxylic Acids; Chlorophyta; Chromatium; Glutamates; Glutamine; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Magnesium; Micrococcus; Models, Biological; Pseudomonas; Pyridoxal Phosphate; Rhodobacter sphaeroides; Rhodospirillum rubrum; Transaminases; Valine | 1971 |
Detection of non-protein amino acids in the presence of protein amino acids. II.
Topics: Alanine; Amino Acids; Autoanalysis; Buffers; Chemical Phenomena; Chemistry; Chromatography; Colorimetry; Cysteine; Hydrogen-Ion Concentration; Isoleucine; Methods; Proteins; Threonine; Urea; Valine | 1972 |
Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides.
Topics: Aeromonas; Alanine; Amides; Amino Acids; Aminocaproates; Aminopeptidases; Dipeptides; Glycine; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine; Valerates; Valine | 1972 |
Maple syrup urine disease (branched-chain keto-aciduria) variant type manifesting as hyperkinetic behaviour and mental retardation. Report of two cases.
Topics: Child, Preschool; Humans; Hyperkinesis; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Pedigree; Pyruvates; Valine | 1972 |
Regulation of aspartokinase activity in a thermophilic bacterium.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Feedback; Homoserine; Isoleucine; Kinetics; Lysine; Methionine; Phosphotransferases; Stereoisomerism; Threonine; Valine | 1972 |
Nutritional aspects of amino acid metabolism. 2. The effects of starvation on hepatic portal-venous differences in plasma amino acid concentration and on liver amino acid concentrations in the rat.
Topics: Amino Acids; Animals; Autoanalysis; Biological Transport; Cystine; Dietary Proteins; DNA; Hepatic Veins; Isoleucine; Leucine; Liver; Male; Organ Size; Ornithine; Perfusion; Portal Vein; Rats; Starvation; Tryptophan; Valine | 1972 |
Quantitative studies on nitrogen metabolism in the bovine rumen. The rate of proteolysis of casein and ovalbumin and the release and metabolism of free amino acids.
Topics: Amino Acids; Ammonia; Animals; Autoanalysis; Caseins; Cattle; Electrophoresis; Female; Half-Life; Isoleucine; Leucine; Lithium; Lysine; Nitrogen; Ovalbumin; Rumen; Valerates; Valine | 1972 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. V. Properties of homoserine kinase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Brevibacterium; Chemical Phenomena; Chemistry; Chromatography, Gel; Homoserine; Hydrogen-Ion Concentration; Isoleucine; L-Lactate Dehydrogenase; Lysine; Methods; Phosphotransferases; Pyruvate Kinase; Spectrophotometry; Threonine; Valine | 1972 |
Ketotic hypoglycaemia associated with transient branched-chain aminoacidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Birth Weight; Blood Glucose; Child; Child, Preschool; Creatinine; Diet Therapy; Female; Growth Hormone; Humans; Hypoglycemia; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Pre-Eclampsia; Pregnancy; Valine | 1972 |
Semiquantitation of leucine, isoleucine, and valine by thin-layer chromatography in management of maple-syrup urine diseases.
Topics: Amniotic Fluid; Ascitic Fluid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Diet Therapy; Evaluation Studies as Topic; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methods; Peritoneal Dialysis; Phenylalanine; Pregnancy; Valine | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food Deprivation; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Isoleucine; Leucine; Pregnancy; Serine; Starvation; Threonine; Time Factors; Valine | 1972 |
The effect of nutrients and precursors on the fatty acid composition of two thermophilic Bacteria.
Topics: Bacillus; Chromatography, Gas; Culture Media; Fatty Acids; Isoleucine; Leucine; Species Specificity; Temperature; Time Factors; Valine | 1972 |
Regulation of valine catabolism in Pseudomonas putida.
Topics: Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Butyrates; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Enzyme Induction; Genetics, Microbial; Glutamates; Isoleucine; Keto Acids; Malonates; Mutation; Oxidation-Reduction; Oxidoreductases; Pseudomonas; Spectrophotometry; Stereoisomerism; Transaminases; Valine | 1972 |
A multichamber equilibrium dialysis apparatus.
Topics: Arginine; Biological Transport; Crystallization; Dialysis; Isoleucine; Kinetics; Leucine; Membranes; Methods; Protein Binding; Proteins; Rotation; Temperature; Valine | 1972 |
Serosal accumulation of amino acids and hepatic lipid levels of rats fed several carbohydrates.
Topics: Amino Acids; Animals; Body Weight; Cholesterol; Chromatography, Gas; Dietary Carbohydrates; Feeding Behavior; Glucose; Intestinal Absorption; Intestine, Small; Isoleucine; Leucine; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Phenylalanine; Polysaccharides; Rats; Starch; Sucrose; Threonine; Valine | 1972 |
Specificity and spectral resolution of an L-glutamate dehydrogenase-monocarboxylic amino acid complex.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Binding Sites; Glutamate Dehydrogenase; Isoleucine; Leucine; Methionine; Protein Binding; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Tyrosine; Ultraviolet Rays; Valine | 1972 |
A basis for the difference in the inhibition of the uptake of various neutral amino acids by lysine in intestinal epithelial cells.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Epithelial Cells; Epithelium; Histidine; Intestinal Mucosa; Intestines; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Rats; Sodium; Threonine; Tryptophan; Valine | 1972 |
Enzyme activity in classical and variant forms of maple syrup urine disease.
Topics: Autoradiography; Carbon Isotopes; Carboxy-Lyases; Child; Dietary Proteins; Female; Fibroblasts; Humans; Isoleucine; Keto Acids; Leucine; Leukocytes; Male; Maple Syrup Urine Disease; Skin; Valine | 1972 |
Net metabolism of plasma amino acids by liver and portal-drained viscera of fed sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animals; Arginine; Aspartic Acid; Blood Flow Velocity; Dietary Proteins; Digestive System; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Liver Circulation; Nitrogen; Ornithine; Phenylalanine; Serine; Sheep; Tyrosine; Valine | 1972 |
L-threonine dehydratase activity of axenically grown Hartmannella culbertsoni.
Topics: Cell-Free System; Hartmannella; Hydro-Lyases; Isoleucine; Kinetics; Pyridoxal Phosphate; Threonine; Valine | 1972 |
Effect of spermine on the uptake of amino acids in Micrococcus lysodeikticus.
Topics: Alanine; Amino Acids; Autoanalysis; Azides; Carbon Isotopes; Carrier Proteins; Cell Membrane; Dinitrophenols; Glucose; Glycine; Isoleucine; Leucine; Micrococcus; Polyamines; Protein Binding; Spermidine; Spermine; Temperature; Valine | 1972 |
Amino acids in amniotic fluid: changes in concentrations during the first half of pregnancy.
Topics: Abortion, Therapeutic; Adult; Alanine; Amino Acids; Amniotic Fluid; Arginine; Chromatography, Ion Exchange; Female; Gestational Age; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Serine; Tyrosine; Valine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
[Rapid separation of aromatic and ramified amino acids by chromatography on ion exchange columns. Application to the surveillance of leucinosis and hyperphenylalaninemia].
Topics: Amino Acids; Chromatography, Ion Exchange; Humans; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Methods; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1972 |
Plasma amino acid response in young men given diets devoid of single essential amino acids.
Topics: Adolescent; Adult; Amino Acids; Deficiency Diseases; Dietary Proteins; Fasting; Female; Humans; Isoleucine; Leucine; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1972 |
Urinary excretion of nitrogen from ( 15 N)valine, ( 15 N)leucine and ( 15 N)isoleucine in malnourished and recovered children.
Topics: Convalescence; Humans; Infant; Infant Nutrition Disorders; Isoleucine; Leucine; Nitrogen; Nitrogen Isotopes; Nutritional Requirements; Urea; Valine | 1972 |
A case of classical maple syrup urine disease "thiamine non-responsive".
Topics: Adult; Animals; Carboxy-Lyases; Child, Preschool; Diet Therapy; Female; Fibroblasts; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Leukocytes; Male; Maple Syrup Urine Disease; Milk; Neurologic Manifestations; Pregnancy; Thiamine; Valine | 1972 |
A simplified method for the preparation of 14 C-labelled branched-chain -oxo acids.
Topics: Amino Acid Oxidoreductases; Caproates; Carbon Isotopes; Catalase; Chromatography, Thin Layer; Isoleucine; Isotope Labeling; Keto Acids; Leucine; Methods; Valerates; Valine | 1972 |
Metabolism of propionate in the vitamin B 12 -deficient rat.
Topics: Acetates; Animals; Injections, Intraperitoneal; Isoleucine; Malonates; Propionates; Rats; Starvation; Valine; Vitamin B 12 Deficiency | 1972 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. VI. Effects of isoleucine and valine on threonine dehydratase activity and its formation.
Topics: Amino Acids; Brevibacterium; Chromatography, Gel; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Molecular Weight; Pyridoxal Phosphate; Threonine; Valine | 1972 |
Hydrocarbons in the millipede Graphidostreptus tumuliporus (Karsch) (Myriapoda: Diplopoda). I. In vivo incorporation of 14 C-labelled precursors into the hydrocarbon fraction.
Topics: Acetates; Animals; Arthropods; Carbon Isotopes; Chromatography; Female; Hydrocarbons; Isoleucine; Kinetics; Lipids; Male; Mevalonic Acid; Palmitic Acids; Sex Factors; Sodium; Structure-Activity Relationship; Valine | 1972 |
Studies of transfer ribonucleic acids and of hemoglobin synthesis in sheep reticulocytes.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Anemia; Animals; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Electrophoresis, Starch Gel; Hemoglobins; Homozygote; Isoleucine; Macromolecular Substances; Methionine; Reticulocytes; RNA, Transfer; Sheep; Tritium; Urea; Valine | 1972 |
Brain serotonin content: physiological regulation by plasma neutral amino acids.
Topics: Amino Acids; Animals; Brain Chemistry; Dietary Carbohydrates; Dietary Proteins; Hydroxyindoleacetic Acid; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1972 |
[Behavior of free essential amino acids in human sweat].
Topics: Adult; Aged; Amino Acids; Chromatography, Ion Exchange; Female; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Phenylalanine; Sweat; Threonine; Valine | 1972 |
Influence of urea, biuret and starch on amino acid patterns in ruminal bacteria and blood plasma and on nitrogen balance of steers fed high fiber purified diets.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bacteria; Cattle; Cellulose; Culture Media; Depression, Chemical; Diet; Dietary Carbohydrates; Digestion; Feces; Glutamates; Hydrolysis; Indenes; Isoleucine; Ketones; Male; Metabolism; Nitrogen; Proline; Rumen; Starch; Stimulation, Chemical; Time Factors; Urea; Urease; Valine; Wood; Zea mays | 1971 |
The inhibition of protein synthesis in a rat brain system by ethionine in vitro and in vivo.
Topics: Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Cycloheximide; Ethionine; Female; Guanosine Triphosphate; In Vitro Techniques; Isoleucine; Leucine; Male; Methionine Sulfoximine; Nerve Tissue Proteins; Phenylalanine; Puromycin; Rats; Ribosomes; RNA, Transfer; Sodium Isotopes; Threonine; Valine | 1971 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
[Maple syrup urine disease with an intermittent relatively benign course].
Topics: Adult; Child, Preschool; Diet Therapy; Female; Humans; Infant; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Oxidoreductases; Valine | 1971 |
Leucine equivalency system in managing branched chain ketoaciduria.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Diet; Diet Therapy; Female; Food Analysis; Growth; Humans; Infant Food; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Keto Acids; Leucine; Maple Syrup Urine Disease; Methods; Phenylalanine; Time Factors; Valine | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Amino acid supplementation of opaque-2 corn diets for growing rats.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cystine; Dietary Proteins; Growth; Isoleucine; Lysine; Male; Methionine; Nitrogen; Nutritional Requirements; Phenylalanine; Rats; Stimulation, Chemical; Threonine; Tyrosine; Valine; Zea mays | 1971 |
Quantitative changes in plasma amino acids induced by oral contraceptives.
Topics: Adult; Alanine; Amino Acids; Contraceptives, Oral; Female; Glutamine; Glycine; Gonadal Steroid Hormones; Humans; Isoleucine; Leucine; Ornithine; Ovulation; Proline; Serine; Tyrosine; Valine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Incorporation in vitro of ( 14 C)leucine into the mitochondrial protein of Lucilia cuprina. 2. Energy requirements.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diptera; Germ-Free Life; In Vitro Techniques; Isoleucine; Leucine; Mitochondria, Muscle; Oligomycins; Oxygen Consumption; Proline; Protein Biosynthesis; Valine | 1971 |
Amino acid sequence of bovine carboxypeptidase A. Isolation and characterization of the thermolytic peptides of the cyanogen bromide fragment F-I.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cyanides; Electrophoresis; Endopeptidases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methods; Peptides; Phenylalanine; Solubility; Temperature; Valine | 1971 |
Amino acid composition of cecal contents and feces in germfree and conventional rabbits.
Topics: Amino Acids; Animals; Cecum; Coprophagia; Feces; Female; Germ-Free Life; Histidine; Hot Temperature; Humans; Isoleucine; Lipids; Lysine; Male; Metals; Methionine; Nitrogen; Organ Size; Proteins; Rabbits; Stress, Physiological; Valine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Cooperative feedback control of barley acetohydroxyacid synthetase by leucine, isoleucine, and valine.
Topics: Benzoates; Chloromercuribenzoates; Edible Grain; Enzyme Repression; Feedback; Glutathione; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Lactates; Leucine; Lyases; Mercaptoethanol; Mercury; Models, Chemical; Osmolar Concentration; Pyruvates; Valine | 1971 |
In vitro mitochondrial complementation in Neurospora crassa.
Topics: Carbon Isotopes; Chromatography, DEAE-Cellulose; Genes; Genetic Complementation Test; Hydro-Lyases; In Vitro Techniques; Isoleucine; Methods; Mitochondria; Molecular Biology; Mutation; Neurospora; Pyruvates; Time Factors; Valine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The biosynthesis of valine from isobutyrate by peptostreptococcus elsdenii and Bacteroides ruminicola.
Topics: Adenosine Triphosphate; Alanine; Bacterial Proteins; Bacteroides; Benzene Derivatives; Bicarbonates; Butyrates; Carbon Dioxide; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Paper; Coenzyme A; Ferredoxins; Glutamine; Hydrogen; Indicators and Reagents; Isoleucine; Leucine; Peptostreptococcus; Phosphates; Valine | 1971 |
Studies on the biosynthesis of mitomycin C by Streptomyces verticillatus.
Topics: Acetamides; Acetates; Alanine; Anhydrides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Formates; Glucose; Glycine; Heptoses; Isoleucine; Leucine; Methionine; Mevalonic Acid; Mitomycins; Models, Biological; Models, Structural; Oxidation-Reduction; Pentosephosphates; Phenylalanine; Serine; Shikimic Acid; Sodium; Spectrophotometry; Streptomyces; Tryptophan; Valine | 1971 |
Effect of specific amino acids on in vitro protein synthesizing system from rats.
Topics: Amino Acids; Aminoacylation; Animals; Aspartic Acid; Carbon Isotopes; Culture Techniques; Female; Histidine; Isoleucine; Male; Methionine; Nutrition Disorders; Peptide Biosynthesis; Phenylalanine; Protein Biosynthesis; Rats; Valine | 1971 |
A variant form of branched-chain keto aciduria.
Topics: Amino Acids; Child Behavior Disorders; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diet Therapy; Dietary Proteins; Female; Heterozygote; Humans; Infant; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Methionine; Motor Skills; Pedigree; Phenylketonurias; Tyrosine; Valine | 1971 |
Stimulation of basic amino acid uptake by certain neutral amino acids in isolated intestinal epithelial cells.
Topics: Alanine; Animals; Arginine; Biological Transport; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Epithelial Cells; Epithelium; Glycine; Histidine; Hydrochloric Acid; Intestinal Mucosa; Intestines; Inulin; Isoleucine; Kinetics; Leucine; Lysine; Male; Mathematics; Methionine; Ornithine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serous Membrane; Sodium; Stimulation, Chemical; Tritium; Tryptophan; Valine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Biochemical studies on a variant of branched chain ketoaciduria in a 19-year-old female.
Topics: Adolescent; Adult; Amino Acids; Carbon Isotopes; Carboxy-Lyases; Child; Child, Preschool; Culture Techniques; Dietary Proteins; Female; Fibroblasts; Galactosidases; Genetic Variation; Humans; Infant; Infant, Newborn; Intelligence; Isoleucine; Keto Acids; Leucine; Leukocytes; Maple Syrup Urine Disease; Oxidoreductases; Valine | 1971 |
Intermittent branched chain ketonuria (variant of maple syrup urine disease).
Topics: Canada; Carboxy-Lyases; Cells, Cultured; Diet Therapy; Female; Fibroblasts; Humans; Infant; Isoleucine; Keto Acids; Leucine; Maple Syrup Urine Disease; Skin; Time Factors; Valine | 1971 |
Effect of essential amino acids on absorption of phenylalanine by rat intestine.
Topics: Amino Acids; Animals; Autoradiography; Carbon Isotopes; Fasting; In Vitro Techniques; Injections; Intestinal Absorption; Isoleucine; Leucine; Lysine; Male; Methionine; Perfusion; Phenylalanine; Rats; Stimulation, Chemical; Stomach; Threonine; Tryptophan; Valine | 1971 |
Amino acid interactions in chick nutrition. 4. Growth, food intake and plasma amino acid patterns.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Depression, Chemical; Feeding Behavior; Growth; Isoleucine; Leucine; Lysine; Time Factors; Valine | 1971 |
Initiation of hemoglobin biosynthesis.
Topics: Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Paper; Genetic Code; Hemoglobins; Isoleucine; Methionine; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; RNA, Transfer; Tritium; Valine | 1971 |
The dissimilation of leucine, isoleucine and valine to volatile fatty acids by adult Fasciola hepatica.
Topics: Acetates; Butyrates; Carbon Isotopes; Fasciola hepatica; Fatty Acids, Volatile; Glucose; Isoleucine; Leucine; Propionates; Valerates; Valine | 1971 |
Nutritional aspects of amino acid metabolism. 1. A rat liver perfusion method for the study of amino acid metabolism.
Topics: Adenosine Triphosphate; Alanine Transaminase; Amino Acids; Animals; Glucose; Halothane; In Vitro Techniques; Isoleucine; Lactates; Leucine; Liver; Methods; Nutritional Physiological Phenomena; Oxygen Consumption; Pentobarbital; Potassium; Pyruvates; Rats; Urea; Valine | 1971 |
Utilization of d-isomers of the dietary indispensable amino acids by Argyrotaenia velutinana larvae.
Topics: Animals; Arginine; Diet; Female; Histidine; Insecta; Isoleucine; Isomerism; Larva; Leucine; Male; Metamorphosis, Biological; Methionine; Phenylalanine; Pupa; Threonine; Tryptophan; Valine | 1971 |
Amino acid analyzer programming for the rapid determination of methionine and lysine.
Topics: Ammonia; Autoanalysis; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Methionine; Methods; Valine | 1971 |
Biosynthetical non-equivalence of the D- and L-valine residues in sporidesmolide I.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, Ion Exchange; Isoleucine; Mathematics; Mitosporic Fungi; Peptide Biosynthesis; Peptides, Cyclic; Stereoisomerism; Valine | 1971 |
[Acute leucinosis, normal psychomotor development at one year of age].
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Diet Therapy; Electroencephalography; Female; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Leucine; Neurologic Manifestations; Peritoneal Dialysis; Protein Deficiency; Psychomotor Disorders; Valine | 1971 |
Patterns of transfer RNA in normal rat liver and during hepatic carcinogenesis.
Topics: Animals; Arginine; Carbon Isotopes; Chromatography; Ethionine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Male; Phenylalanine; Rats; RNA, Transfer; Tritium; Valine | 1967 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[Behavior of free amino acids in the blood of leukemia patients following amino acid infusion].
Topics: Adult; Aged; Amino Acids; Arginine; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1968 |
Protein consumption and intake of essential amino acids, niacin and calcium before and after wearing complete dentures.
Topics: Adult; Aged; Amino Acids; Calcium; Denture, Complete; Eating; Female; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Nicotinic Acids; Nutritional Physiological Phenomena; Phenylalanine; Proteins; Threonine; Tryptophan; Valine | 1969 |
Initiation of the alpha chain of rabbit hemoglobin.
Topics: Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography, Gel; Globins; Hemoglobins; Hydantoins; Isoleucine; Peptide Biosynthesis; Peptides; Phenylhydrazines; Rabbits; Reticulocytes; Ribosomes; Trypsin; Valine | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Gaschromatographic studies of microbial components. 3. Research on precursor of branched chain fatty acids of Staphylococcus aureus and Streptomyces lavenduulae.
Topics: Acetates; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Isoleucine; Methionine; Propionates; Sodium; Staphylococcus; Streptomyces; Valine | 1968 |
Sedimentation characteristics of template RNA from rabbit reticulocytes and rat liver.
Topics: Animals; Centrifugation; Chemical Phenomena; Chemistry; Chloroplasts; Escherichia coli; Euglena; In Vitro Techniques; Isoleucine; Leucine; Liver; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; Ribosomes; RNA; Valine | 1965 |
[Co-operative inhibitory effects of L-lysine with other amino acids on an aspartokinase from Escherichia coli].
Topics: Enzyme Repression; Enzymes; Escherichia coli; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Molecular Biology; Mutation; Phenylalanine; Phosphotransferases; Valine | 1965 |
Interference with valine and isoleucine biosynthesis by cyclic hydroxamic acids.
Topics: Barbiturates; Escherichia coli; Hydroxamic Acids; In Vitro Techniques; Iron; Isoleucine; Magnesium; Pyrazines; Valine | 1965 |
Heterogeneity in P22 transducing particles.
Topics: Centrifugation; Enzymes; Genes; Histidine; In Vitro Techniques; Isoleucine; Salmonella Phages; Salmonella typhimurium; Valine | 1965 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
Purification and properties of isoleucyl ribonucleic acid synthetase from Escherichia coli.
Topics: Adenosine Triphosphate; Chemistry Techniques, Analytical; Chromatography; Escherichia coli; Hot Temperature; In Vitro Techniques; Isoleucine; Ligases; Magnesium; RNA, Bacterial; Trypsin; Ultracentrifugation; Valine | 1966 |
Relationship of structure to biological activity of some unsaturated derivatives of cyclopentaneglycine.
Topics: Alkenes; Cycloparaffins; Cyclopentanes; Escherichia coli; Glycine; In Vitro Techniques; Isoleucine; Methionine; Valine | 1965 |
Lack of specificity in the formation amino-acyl-sRNA as a possible source of coding errors.
Topics: Bacillus; Escherichia coli; Genetic Code; Hot Temperature; In Vitro Techniques; Isoleucine; Ligases; RNA, Transfer; Valine | 1965 |
Over-all synthesis of isoleucine by membrane fractions of Salmonella typhimurium.
Topics: Butyrates; In Vitro Techniques; Isoleucine; Protoplasts; Pyruvates; Salmonella typhimurium; Valine | 1965 |
Accumulation of keto acids during the growth cycle of Escherichia coli.
Topics: Amino Acids; Escherichia coli; Glutarates; In Vitro Techniques; Isoleucine; Keto Acids; Leucine; Nitrogen; Pyruvates; Quaternary Ammonium Compounds; Serine; Valine | 1966 |
Amino-acid-binding protein released from Escherichia coli by osmotic shock.
Topics: Bacterial Proteins; Biological Transport; Cold Temperature; Escherichia coli; Isoleucine; Kinetics; Leucine; Osmosis; Valine | 1966 |
Orientation of the isoleucine-valine genes in the Salmonella typhimurium linkage map.
Topics: Chromosome Mapping; Genes; Histidine; Isoleucine; Methionine; Mutation; Salmonella Phages; Salmonella typhimurium; Valine | 1966 |
Valine sensitivity of Escherichia coli K-12.
Topics: Escherichia coli; Hydro-Lyases; Isoleucine; Streptomycin; Threonine; Valine | 1966 |
[Deamination of threonine and serine in Salmonella typhimurium].
Topics: Ammonia; Isoleucine; Keto Acids; Salmonella typhimurium; Serine; Threonine; Valine | 1964 |
Some effects of spermine on Escherichia coli.
Topics: Anti-Bacterial Agents; Arginine; Carbon Isotopes; Cell Membrane Permeability; Chloramphenicol; DNA; Drug Resistance, Microbial; Escherichia coli; Glucose; Guanine; Isoleucine; Leucine; Phenylalanine; Phosphorus Isotopes; Potassium; Proteins; RNA; Spermine; Streptomycin; Uracil; Valine | 1966 |
Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. Altered threonine deaminase in an is-1 mutant responding to threonine.
Topics: Alcohol Oxidoreductases; Aldehyde-Lyases; Binding Sites; Cell-Free System; Culture Media; Enzyme Activation; Feedback; Haploidy; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Molecular Weight; Mutation; Saccharomyces; Species Specificity; Stimulation, Chemical; Threonine; Valine | 1969 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. I. The plasma amino acid ratio in normal full-term and preterm infants.
Topics: Amino Acids; Blood Chemical Analysis; Chromatography, Paper; Gestational Age; Glutamine; Glycine; Humans; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Methionine; Serine; Taurine; Valine | 1969 |
Amino acid synthesis by the mitochondria of Neurospora crassa. I. Dependence on respiration of mitochondria.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cyanides; Dinitrophenols; Glutamates; Isoleucine; Keto Acids; Mitochondria; Neurospora; Oligomycins; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Polarography; Pyruvates; Succinates; Valine | 1969 |
Properties of threonine deaminase from a bacterium able to use threonine as sole source of carbon.
Topics: Adenosine Triphosphate; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Citrates; Dialysis; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Leucine; Molecular Weight; Pseudomonas; Threonine; Valine | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Mass spectrometry of phenylthiohydantoin (PTH) amino acids.
Topics: Alanine; Amino Acids; Chromatography, Gas; Isoleucine; Leucine; Proline; Spectrum Analysis; Valine | 1969 |
Plasma amino acid concentration and the regulation of albumin synthesis.
Topics: Amino Acids; Animals; Blood; Carbon Isotopes; Isoleucine; Leucine; Liver; Male; Perfusion; Protein Deficiency; Rats; Serum Albumin; Urea; Valine | 1969 |
Isosmotic regulation in isolated surviving nerves of Eriocheir sinensis Milne Edwards.
Topics: Adaptation, Physiological; Amino Acids; Ammonia; Animals; Cell Membrane Permeability; Crustacea; Hypotonic Solutions; Isoleucine; Leucine; Neurons; Osmotic Pressure; Phenylalanine; Proline; Seawater; Tyrosine; Valine; Water-Electrolyte Balance | 1969 |
Effects of valine deprivation on ribosome formation in HeLa cells.
Topics: Cell Nucleus; Cycloheximide; Female; HeLa Cells; Humans; In Vitro Techniques; Isoleucine; Leucine; Lysine; Ribosomes; RNA, Neoplasm; Valine | 1969 |
[Paper- and thin layer chromatography of amino acids in infusion solutions].
Topics: Amino Acids; Arginine; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Solutions; Threonine; Tryptophan; Valine | 1969 |
Amino acid composition of chromatographically separated beta-casein A3.
Topics: Acrylates; Amino Acids; Animals; Arginine; Caseins; Cattle; Chromatography; Electrophoresis; Female; Gels; Histidine; Hydrolases; Isoleucine; Proline; Starch; Valine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
The iv-3 mutants of Neurospora crassa. I. Genetic and biochemical characteristics.
Topics: Chromatography, Paper; Chromosome Mapping; Complement System Proteins; Culture Media; Isoleucine; Molecular Biology; Neurospora; Pyruvates; Recombination, Genetic; Valine | 1969 |
The iv-3 mutants of Neurospora crassa. II. Activity of acetohydroxy acid synthetase.
Topics: Centrifugation; Isoleucine; Lyases; Molecular Biology; Mutation; Neurospora; Pyruvates; Valine | 1969 |
Calf and pea histone IV. 3. Complete amino acid sequence of pea seedling histone IV; comparison with the homologous calf thymus histone.
Topics: Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Histones; Isoleucine; Lysine; Maleates; Methods; Peptides; Plants; Species Specificity; Thymus Gland; Trypsin; Valine | 1969 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. II. The plasma amino acid ratio in intrauterine malnutrition (small for dates' full-term, preterm and twin infants).
Topics: Amino Acids; Birth Weight; Chromatography, Paper; Female; Fetal Diseases; Gestational Age; Glutamine; Glycine; Humans; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Methionine; Nutrition Disorders; Pregnancy; Serine; Taurine; Twins; Valine | 1969 |
[On the influence of contraceptive pills on serum amino acids in comparison with results typical for sex, menstrual cycle and pregnancy].
Topics: Adult; Alanine; Amino Acids; Citric Acid Cycle; Contraceptives, Oral; Female; Glycine; Humans; Isoleucine; Leucine; Male; Menstruation; Methionine; Pregnancy; Proline; Sex Factors; Threonine; Tyrosine; Urea; Valine | 1969 |
Studies of mutants inhibited by their own metabolites in Saccharomyces cerevisiae. II. Genetic and enzymatic analysis of three classes of mutants.
Topics: Aminobutyrates; Feedback; Genes; Isoleucine; Ligases; Membrane Transport Proteins; Methionine; Molecular Biology; Mutation; Saccharomyces; Valine | 1969 |
Amino acid content of muscle and plasma with altered pH.
Topics: Acidosis, Respiratory; Alanine; Alkalosis; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cell Membrane; Citrulline; Extracellular Space; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Muscles; Partial Pressure; Potassium Deficiency; Rats; Serine; Threonine; Valine | 1970 |
Taxonomy of phytopathogenic pseudomonads.
Topics: Alanine; Benzoates; Fluorescence; Isoleucine; Keto Acids; Lysine; Microbial Sensitivity Tests; Nicotiana; Nutritional Physiological Phenomena; Pigmentation; Plants; Plants, Toxic; Pseudomonas; Species Specificity; Spermine; Valine | 1970 |
Purification, properties, and feedback control of L-threonine dehydratase from spinach.
Topics: Binding Sites; Chemical Precipitation; Chromatography, Ion Exchange; Coenzymes; Cold Temperature; Enzyme Activation; Hot Temperature; Hydro-Lyases; Isoleucine; Kinetics; Lithium; Mercury; Plants; Potassium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Threonine; Valine | 1970 |
Studies on the pink, adenine-deficient strains of Candida albicans. I. Cultural and morphological characteristics.
Topics: Adenine; Agglutination Tests; Amphotericin B; Animals; Candida; Cytoplasm; Cytoplasmic Granules; Drug Resistance, Microbial; Female; Genetics, Microbial; Isoleucine; Mice; Mutation; Pigmentation; Sulfonic Acids; Temperature; Ultraviolet Rays; Valine; Virulence | 1970 |
Comparative sensitivity of specific amino acid ratios versus "essential to nonessential" amino acid ratio.
Topics: Adult; Amino Acids; Child; Cystine; Diet; Female; Glycine; Humans; Isoleucine; Kwashiorkor; Leucine; Nutrition Disorders; Pregnancy; Serine; Socioeconomic Factors; Tyrosine; Valine | 1970 |
A new variant of maple syrup urine disease (branched chain ketoaciduria). Clinical and biochemical evaluation.
Topics: Amino Acids; Carboxy-Lyases; Creatinine; Diet Therapy; Enzyme Induction; Female; Fibroblasts; Humans; Infant; Isoleucine; Keto Acids; Leucine; Leukocytes; Maple Syrup Urine Disease; Uric Acid; Valine | 1970 |
Amino acid interactions in chick nutrition. 2. Interrelationships between leucine, isoleucine and valine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Glycine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Tyrosine; Valine | 1970 |
[On the structure of malformin. I. Syntheses of protected bis-thiol peptides].
Topics: Chemical Phenomena; Chemistry; Cysteine; Isoleucine; Leucine; Peptides; Sulfur; Valine | 1970 |
The amino acid composition of gray matter ganglioside-peptides of normal human and Tay-Sachs brains.
Topics: Alanine; Amino Acids; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Cystine; Gangliosides; Glycine; Humans; Isoleucine; Leucine; Lipidoses; Methionine; Peptides; Threonine; Trypsin; Tyrosine; Valine | 1970 |
Studies on the symmetric synthesis of alpha-amino acids. II. New systems for highly specific asymmetric synthesis with conservation of the Chiral reagent.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Crystallography; Indicators and Reagents; Isoleucine; Keto Acids; Stereoisomerism; Valine | 1970 |
Study of the racemization of soe neutral alpha-amino acids in acid solution using gas chromatographic techniques.
Topics: Alanine; Amino Acids; Aminobutyrates; Chemical Phenomena; Chemistry; Chromatography, Gas; Hydrochloric Acid; Isoleucine; Kinetics; Stereoisomerism; Temperature; Time Factors; Valine | 1970 |
Alterations in plasma-free amino acids in dogs with hepatic insufficiency.
Topics: Amino Acids; Animals; Dogs; Ischemia; Isoleucine; Leucine; Liver Diseases; Lysine; Methionine; Phenylalanine; Plasma; Threonine; Tryptophan; Valine | 1970 |
The conversion of valine to propionylcarnitine in isolated rat liver mitochondria.
Topics: Animals; Carbon Isotopes; Carnitine; Dinitrophenols; Glucose; Hexokinase; Isoleucine; Mitochondria, Liver; Propionates; Rats; Tritium; Uncoupling Agents; Valerates; Valine | 1970 |
The venous plasma free amino acid levels during the first hours of life. I. After normal and short gestation and gestation complicated by hypertension, with special reference to the "small for dates" syndrome.
Topics: Alanine; Amino Acids; Arginine; Birth Weight; Blood Glucose; Body Height; Chromatography, Ion Exchange; Female; Gestational Age; Glycine; Growth; Growth Disorders; Humans; Hypertension; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Lysine; Ornithine; Polythiazide; Pregnancy; Pregnancy Complications, Cardiovascular; Protein Deficiency; Time Factors; Valine; Veins | 1970 |
Uptake of individual amino acids by perfused rat liver: effect of acute uremia.
Topics: Amino Acids; Animals; Fasting; Female; Glutamates; Isoleucine; Leucine; Liver; Lysine; Perfusion; Protein Biosynthesis; Rats; Serine; Threonine; Uremia; Valine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Amino acid sequences of some common Japanese strains of tobacco mosaic virus.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Endopeptidases; Isoleucine; Threonine; Tobacco Mosaic Virus; Valine | 1970 |
[Purine metabolism and riboflavin production in microorganisms. VI. The effect of L-valine on the flavinogenesis of Candida guilliermondii (Cast.) Lang. et G].
Topics: Absorption; Butanones; Candida; Carbon Isotopes; Chromatography, Paper; Iron; Isoleucine; Purines; Riboflavin; Spectrum Analysis; Stereoisomerism; Valine | 1970 |
Amino acid interactions in chick nutrition. 3. Interdependence in amino acid requirements.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Glycine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Properties of threonine deaminase in Mycobacterium pellegrino.
Topics: Chemical Precipitation; Flavin-Adenine Dinucleotide; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Mycobacterium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sulfates; Temperature; Thiamine Pyrophosphate; Valine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
[Attempted diet therapy of a case of maple syrup disease].
Topics: Diet Therapy; Humans; Infant; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Valine | 1970 |
Response of adult rats to low dietary levels of essential amino acids.
Topics: Amino Acids; Animals; Body Weight; Cystine; Deficiency Diseases; Diet; Dietary Proteins; Female; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Biosynthesis of compounds similar to aspergillic acid.
Topics: Amino Acids; Aspergillus; Chromatography; Culture Media; Deuterium; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Methods; Pyrazines; Spectrum Analysis; Valine; Yeast, Dried | 1970 |
Hormone and amino acid levels in altered nutritional states.
Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Female; Growth Hormone; Humans; Insulin; Isoleucine; Leucine; Male; Nutritional Physiological Phenomena; Obesity; Protein Deficiency; Starvation; Valine | 1970 |
Conformations of amino acids calculated from molecular orbital theory.
Topics: Chemical Phenomena; Chemistry, Physical; Isoleucine; Leucine; Quantum Theory; Serine; Valine; X-Ray Diffraction | 1970 |
Influence of site of blood withdrawal and stage of fast on concentrations of plasma free amino acids in the growing pig.
Topics: Amino Acids; Analysis of Variance; Animal Feed; Animals; Aorta, Abdominal; Blood Specimen Collection; Dietary Proteins; Fasting; Functional Laterality; Intubation; Isoleucine; Jugular Veins; Leucine; Lysine; Methionine; Portal Vein; Swine; Threonine; Time Factors; Tryptophan; Valine; Venae Cavae | 1970 |
Influence of time of fast on concentrations of free amino acids in plasma and total amino acids in liver protein of young swine.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Arginine; Chromatography, Ion Exchange; Cystine; Dietary Proteins; Fasting; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Swine; Threonine; Time Factors; Tyrosine; Valine | 1970 |
Effect of ovarian steroids on maintenance of pregnancy in rats fed diets devoid of one essential amino acid.
Topics: Amino Acids; Animals; Body Weight; Deficiency Diseases; DNA; Estrone; Female; Fetal Death; Isoleucine; Liver; Lysine; Muscles; Organ Size; Placenta; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Progesterone; Rats; RNA; Threonine; Uterus; Valine | 1970 |
Isolation and characterization of a lysine-sensitive aspartokinase from a multicellular plant.
Topics: Adenosine Triphosphate; Alanine; Aspartic Acid; Enzyme Activation; Isoleucine; Kinetics; Leucine; Lysine; Magnesium; Manganese; Methionine; Phosphotransferases; Plants; Threonine; Valine; Zea mays | 1970 |
The isoleucine and valine nutrition of young laying pullets as influenced by excessive dietary leucine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Chickens; Eggs; Isoleucine; Leucine; Valine | 1970 |
The effect on the nitrogen balance of the ratio essential-non-essential amino acids in intravenously infused solutions.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Blood Urea Nitrogen; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proline; Threonine; Tryptophan; Valine | 1970 |
Purification of yellow lupin seed tRNA's specific for isoleucine and some other amino acids.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Isoleucine; Leucine; Lysine; Magnesium; Nucleic Acid Denaturation; Nucleotides; RNA, Transfer; Seeds; Temperature; Threonine; Valine | 1970 |
[Hormonal regulation at the level of transfer RNA. I. Comparative study of transfer RNA from the liver of immature hens and laying hens].
Topics: Aging; Alanine; Animals; Carbon Isotopes; Chickens; Chromatography, Ion Exchange; Estradiol; Female; Isoleucine; Kinetics; Leucine; Ligases; Liver; Phenols; RNA, Transfer; Serine; Tritium; Valine | 1970 |
Properties and substrate specificity of the leucyl-, the threonyl- and the valyl-transfer-ribonucleic acid synthetases from Aesculus species.
Topics: Alanine; Chromatography, DEAE-Cellulose; Glycine; Isoleucine; Leucine; Ligases; Phosphorus Isotopes; Plants; RNA, Transfer; Seeds; Threonine; Valine | 1970 |
Carbon dioxide fixation in green sulphur bacteria.
Topics: Acetates; Bacteria; Carbon Dioxide; Citric Acid Cycle; Fluoroacetates; Glutarates; Glycolysis; Iodoacetates; Isoleucine; Leucine; Metabolism; Photosynthesis; Polysaccharides, Bacterial; Pyruvates; Quaternary Ammonium Compounds; Valerates; Valine | 1970 |
Vitamin B12-dependent methylmalonicaciduria: amino acid toxicity, long chain ketonuria, and protective effect of vitamin B12.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Coenzyme A; Diet Therapy; Dietary Proteins; Humans; Isoleucine; Ketones; Leucine; Leukocytes; Male; Malonates; Methionine; Nutritional Requirements; Propionates; Threonine; Valine; Vitamin B 12 | 1970 |
Lysine uptake in cultured Trypanosoma cruzi: interactions of competitive inhibitors.
Topics: Alanine; Animals; Biological Transport; Cysteine; Glycine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma; Tyrosine; Valine | 1970 |
Four radiation sensitive mutants of Saccharomyces. Survival after UV- and x-ray-irradiation as well as UV-induced reversion rates from isoleucine-valine dependence to independence.
Topics: Cell Survival; Diploidy; Genetics, Microbial; Haploidy; Isoleucine; Kinetics; Mutation; Phenotype; Radiation Dosage; Radiation Genetics; Saccharomyces; Time Factors; Ultraviolet Rays; Valine | 1970 |
[Experiences with a new amino acid analyzer for a rapid analysis].
Topics: Amino Acids; Autoanalysis; Homocystine; Homocystinuria; Humans; Infant, Newborn; Infant, Premature, Diseases; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Methionine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1970 |
[Report of a case of pernicious anemia associated with marked methylmalonic aciduria after valine load].
Topics: Aged; Anemia, Pernicious; Female; Humans; Isoleucine; Malonates; Valine; Vitamin B Deficiency | 1970 |
Milk production response to supplementation with encapsulated methionine per Os or casein per abomasum.
Topics: Abomasum; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Caseins; Cattle; Female; Glycine; Isoleucine; Kaolin; Lactation; Leucine; Methionine; Milk; Perfusion; Phenylalanine; Pregnancy; Triglycerides; Valine | 1970 |
The amino acid ratio and hydroxyproline creatinine index in marginal protein-calorie malnutrition.
Topics: Amino Acids; Animals; Body Weight; Child, Preschool; Chromatography, Paper; Creatinine; Diet; Female; Glutamine; Glycine; Humans; Hydroxyproline; Infant; Infant Nutrition Disorders; Isoleucine; Leucine; Male; Methionine; Milk; Protein Deficiency; Serine; Taurine; Uganda; Valine | 1970 |
Effect of vitamin B6 depletion in adult man on the plasma concentration and the urinary excretion of free amino acids.
Topics: Adult; Alanine; Amino Acids; Fasting; Glycine; Humans; Isoleucine; Leucine; Male; Pyridoxine; Serine; Threonine; Valine; Vitamin B 6 Deficiency | 1971 |
Effect of essential amino acid restriction on the growth of female C57BL mice and their implanted BW10232 adenocarcinomas.
Topics: Adenocarcinoma; Amino Acids; Animals; Body Weight; Deficiency Diseases; Female; Isoleucine; Leucine; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Rats; Threonine; Transplantation, Homologous; Tryptophan; Tyrosine; Valine | 1971 |
Alteration in the urinary excretion rate of amino acids and nitrogen by dietary means in obese and normal human subjects.
Topics: Adult; Alanine; Amino Acids; Creatinine; Female; Humans; Isoleucine; Leucine; Male; Nitrogen; Obesity; Protein Deficiency; Renal Aminoacidurias; Starvation; Taurine; Urea; Valine | 1971 |
Urinary amino acid excretion in patients with scleroderma.
Topics: Arginine; Aspartic Acid; Chelating Agents; Female; Glutamates; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Renal Aminoacidurias; Scleroderma, Systemic; Threonine; Tyrosine; Valine | 1971 |
Histones of polytene and nonpolytene nuclei of Drosophila melanogaster.
Topics: Animals; Aspartic Acid; Birds; Cattle; Cell Nucleus; Drosophila; Echinodermata; Electrophoresis; Equipment and Supplies; Histidine; Histones; Isoleucine; Larva; Lysine; Methods; Molecular Weight; Salivary Glands; Serine; Thymus Gland; Valine | 1971 |
Biosynthesis of isoleucine and valine in Rhodopseudomonas spheroides: regulation of threonine deaminase activity.
Topics: Cell-Free System; Culture Media; Enzyme Repression; Genetics, Microbial; Hydro-Lyases; Isoleucine; Isomerases; Ligases; Mutation; Rhodopseudomonas; Threonine; Transaminases; Valine | 1971 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. 3. The plasma amino acid ratio in infants born after pregnancies complicated by toxaemia, placental infarction, impaired umbilical circulation and chronic maternal diseas
Topics: Amino Acids; Chronic Disease; Female; Glutamine; Glycine; Heart Defects, Congenital; Heart Failure; Humans; Infant, Newborn; Infarction; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pyelonephritis; Serine; Taurine; Torsion Abnormality; Umbilical Cord; Valine | 1971 |
Unequal synthesis of globin chains after extended incubation of rabbit reticulocytes with L-O-methylthreonine.
Topics: Acrylates; Blood Proteins; Carbon Isotopes; Electrophoresis; Gels; Globins; Hemoglobins; Isoleucine; Leucine; Methylation; Peptide Biosynthesis; Phosphorus Isotopes; Reticulocytes; Ribosomes; RNA, Messenger; Spectrum Analysis; Threonine; Tritium; Ultraviolet Rays; Valine | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Molecular orbital calculations on the conformation of polypeptides and proteins. VII. Refined calculations on the alanyl residue.
Topics: Alanine; Albumins; Carboxypeptidases; Chymotrypsin; Dipeptides; Hydrogen; Isoleucine; Leucine; Models, Structural; Muramidase; Myoglobin; Probability; Proteins; Quantum Theory; Ribonucleases; Rotation; Valine | 1971 |
The influence of pre-eclampsia and diabetes mellitus on plasma free amino acids in maternal, umbilical vein and infant blood.
Topics: Amino Acids; Aminobutyrates; Aspartic Acid; Birth Weight; Blood Proteins; Cesarean Section; Estriol; Female; Gestational Age; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Natural Childbirth; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Umbilical Veins; Valine | 1971 |
Inhibition of amino acid uptake by ATP in isolated intestinal epithelial cells.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine; Amino Acids; Animals; Binding Sites; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Epithelium; Guanine Nucleotides; In Vitro Techniques; Intestinal Mucosa; Isoleucine; Leucine; Lysine; Male; Phosphates; Rats; Time Factors; Valine | 1971 |
The entry of amino acids into the myocardium of the growing rat in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Diffusion; Glycine; Heart; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myocardium; Phenylalanine; Protein Binding; Protein Biosynthesis; Rats; Serine; Taurine; Tryptophan; Tyrosine; Valine | 1971 |
Threonine deaminases from Saccharomyces cerevisiae mutationally altered in regulatory properties.
Topics: Binding Sites; Cell-Free System; Centrifugation, Density Gradient; Depression, Chemical; Drug Resistance, Microbial; Enzyme Activation; Genetics, Microbial; Hydro-Lyases; Isoleucine; Kinetics; Mathematics; Models, Chemical; Molecular Weight; Mutation; Saccharomyces; Species Specificity; Spectrophotometry; Stimulation, Chemical; Sulfides; Threonine; Time Factors; Valine | 1971 |
The uptake of various amino acids by the mouse brain in vivo.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Brain; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Response of oxidative phosphorylation in rat liver to prolonged protein depletion.
Topics: Animals; Arginine; Caseins; Cystine; Dietary Proteins; Glutamates; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Oxidative Phosphorylation; Oxygen Consumption; Phenylalanine; Phosphates; Protein Deficiency; Rats; Succinate Dehydrogenase; Succinates; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
Interrelationships between level of amino acids in plasma and tissues during starvation.
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; Intestine, Small; Isoleucine; Kidney; Leucine; Liver; Male; Methionine; Muscles; Myocardium; Phenylalanine; Rats; Starvation; Tyrosine; Valine | 1971 |
The relationship of adrenal glucocorticoids to transaminase activity and gluconeogenesis in the intact rat.
Topics: Adrenalectomy; Alanine; Animals; Aspartate Aminotransferases; Aspartic Acid; Biological Transport; Blood Glucose; Carbon Isotopes; Cell Membrane Permeability; Chromatography, Ion Exchange; Extracellular Space; Fasting; Glucocorticoids; Gluconeogenesis; Glucose; Glutamates; Glycine; Isoleucine; Kinetics; Liver; Methionine; Phenylalanine; Proline; Rats; Transaminases; Tritium; Tyrosine; Valine; Water | 1971 |
Structure of the large -chain polyribosome of rabbit reticulocytes rendered isoleucine-deficient by O-methylthreonine.
Topics: Animals; Antimetabolites; Carbon Isotopes; Centrifugation, Density Gradient; Depression, Chemical; Genetic Code; Hemoglobins; Isoleucine; Macromolecular Substances; Methylation; Models, Biological; Models, Chemical; Molecular Biology; Peptide Biosynthesis; Peptide Hydrolases; Puromycin; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Spectrophotometry; Threonine; Ultraviolet Rays; Valine | 1971 |
Studies on conversion of amino fermentation. II. Effect of 6-mercaptopurine on formation of alpha-acetolactate synthase.
Topics: Acetoacetates; Carboxy-Lyases; Culture Media; Enterobacter; Fermentation; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Mercaptopurine; Phosphates; Valine | 1971 |
Simplified thin layer chromatography screening test for detection of important hyperaminoacidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography, Thin Layer; Humans; Isoleucine; Leucine; Mass Screening; Methionine; Methods; Phenylalanine; Tyrosine; Valine | 1971 |
Vitamin B12 deficiency in the rat fed high protein rations.
Topics: Amino Acids; Animals; Caseins; Depression, Chemical; Dietary Proteins; Formates; Glycine; Growth; Isoleucine; Male; Malonates; Nitrogen; Proline; Propionates; Rats; Serine; Stereoisomerism; Threonine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
Dietary regulation of plasma insulin and growth hormone concentrations in sheep.
Topics: Acetates; Animal Feed; Animals; Blood Glucose; Butyrates; Diet; Dietary Proteins; Fasting; Glucose; Growth Hormone; Insulin; Intestinal Mucosa; Isoleucine; Male; Nitrogen; Phenylalanine; Propionates; Sheep; Tyrosine; Valine | 1971 |
On the origin of d-aminoacid residues in microbial peptides.
Topics: Chemistry, Organic; Fungi; Isoleucine; Isomerism; Mass Spectrometry; Organic Chemistry Phenomena; Peptide Biosynthesis; Peptides; Peptides, Cyclic; Stereoisomerism; Valine | 1971 |
Evidence for separate systems for the transport of neutral and basic amino acids across the blood-brain barrier.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Glycine; Injections, Intraperitoneal; Isoleucine; Lysine; Male; Mice; Phenylalanine; Rats; Seizures; Valine | 1971 |
[Regulation of the functioning of 2 biosynthetic pathways in Saccharomyces cerevisiae: threonine-methionine and isoleucine-valine].
Topics: Enzyme Repression; Feedback; Genetics, Microbial; Isoleucine; Methionine; Models, Biological; Mutation; Saccharomyces; Threonine; Valine | 1967 |
Synthesis of 4-L-valine-6-L-threonine-, 4-L-isoleucine-6-L-threonine-, 4-L-leucine-6-L-threonine-, 4-L-valine-, and 4-L-isoleucine-bradykinin and their O-acetyl compounds.
Topics: Animals; Bradykinin; Guinea Pigs; Isoleucine; Leucine; Threonine; Valine | 1967 |
[Analysis of amino acids by column chromatography in the presense of heavy metal cations].
Topics: Amino Acids; Chromatography, Ion Exchange; Copper; Cystine; Histidine; Iron; Isoleucine; Leucine; Metals; Methionine; Nickel; Valine | 1967 |
[Synthesis of the bovine insulin A-chain according to the Merrifield method, using exclusively the p-nitrophenyl esters of tert.-butyloxycarbonyl-amino acids].
Topics: Amino Acids; Animals; Cattle; Cysteine; Insulin; Isoleucine; Nitrophenols; Peptides; Serine; Solutions; Spectrophotometry; Valine | 1967 |
Fractionation of plant transfer ribonucleic acid by hydroxyapatite column.
Topics: Carbon Isotopes; Chromatography; Hydroxyapatites; Isoleucine; Leucine; Methionine; RNA, Transfer; Seeds; Valine | 1967 |
Fractionation of transfer ribonucleic acids from Torulopsis utilis. IV. Purification of the alanine, valine and isoleucine transfer ribonucleic acids by column chromatography.
Topics: Alanine; Chromatography; Cryptococcus; Isoleucine; Ribonucleases; RNA, Bacterial; RNA, Transfer; Valine | 1967 |
[Amino acids which are able to antagonize the antipolio effect of guanidine and D-penicillamine. Common features of their genetic codes].
Topics: Amino Acids; Aminobutyrates; Cysteine; Ethionine; Genetic Code; Guanidines; Isoleucine; Leucine; Methionine; Penicillamine; Phenylalanine; Poliomyelitis; Valine | 1967 |
[Paper chromatographic amino acids analysis of natural compounds].
Topics: Amino Acids; Arginine; Chemistry Techniques, Analytical; Chromatography, Paper; Cystine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Oxidation-Reduction; Phenylalanine; Proteins; Solvents; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Essential amino acids for milk protein synthesis in the in vitro secretory cell and stimulation by elevated levels.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Caseins; Cattle; Culture Techniques; Cystine; Female; Glutamine; Histidine; Isoleucine; Lactation; Lactoglobulins; Leucine; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Pregnancy; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Application of Crotalus atrox venom alpha-protease for amino acid sequence determination.
Topics: Amino Acid Sequence; Animals; Chromatography; Electrophoresis; Isoleucine; Leucine; Methods; Peptide Hydrolases; Peptides; Snakes; Valine; Venoms | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. I. Threonine deaminase.
Topics: Cell-Free System; Drug Stability; Genetics, Microbial; Haploidy; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; L-Lactate Dehydrogenase; Mutation; Saccharomyces; Valine | 1968 |
The regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. 2. Identification and characterization of mutants lacking the acetohydroxyacid synthetase.
Topics: Butanones; Carboxy-Lyases; Cell-Free System; Chromatography, Thin Layer; Colorimetry; Genetics, Microbial; Haploidy; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactates; Mutation; Pyruvates; Saccharomyces; Valine | 1968 |
Associations among food and protein intake, serine dehydratase, and plasma amino acids.
Topics: Adaptation, Physiological; Amino Acids; Animals; Dietary Proteins; Homeostasis; Hydro-Lyases; Isoleucine; L-Serine Dehydratase; Leucine; Liver; Male; Nutritional Physiological Phenomena; Rats; Serine; Threonine; Valine | 1968 |
[On the clinical picture and pathological anatomy of the maple syrup disease ("branded chain ketoaciduria"). Report on 2 cases in 1 family].
Topics: Body Height; Body Weight; Diet Therapy; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Prognosis; Valine | 1968 |
Origin of cyanide in cultures of a psychrophilic basidiomycete.
Topics: Amino Acids; Aminohydrolases; Basidiomycota; Carbon Isotopes; Chemistry Techniques, Analytical; Chromatography, Paper; Cyanides; Glucosidases; Isoleucine; Ketones; Valine | 1968 |
Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. I. Effect of nonpolar L-amino acids.
Topics: Acetates; Alanine; Amino Acids; Anhydrides; Aspartic Acid; Bacillus; Binding Sites; Detergents; Drug Antagonism; Drug Synergism; Feedback; Glycine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Phosphotransferases; Threonine; Tryptophan; Valine | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
Isolation of a protein fraction from reticulocyte ribosomes required for de novo synthesis of hemoglobin.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Ethylmaleimide; Hemoglobins; Isoleucine; Molecular Weight; Peptide Hydrolases; Polynucleotides; Potassium Chloride; Proteins; Rabbits; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Transfer; Tritium; Trypsin; Ultracentrifugation; Uracil Nucleotides; Valine | 1968 |
The molecular structures of vertebrate skin collagens. A comparative study.
Topics: Amino Acids; Animals; Anura; Arginine; Autoanalysis; Biological Evolution; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Chromatography; Collagen; Electrophoresis; Fishes; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Leucine; Methionine; Optical Rotatory Dispersion; Proline; Serine; Sharks; Skin; Snakes; Solubility; Temperature; Threonine; Valine | 1968 |
Biosynthesis of long-chain hydrocarbons. II. Studies on the biosynthetic pathway in tobacco.
Topics: Acetates; Butyrates; Caproates; Caprylates; Carbon Isotopes; Chromatography, Thin Layer; Fatty Acids; Hydrocarbons; Isoleucine; Leucine; Lipid Metabolism; Nicotiana; Plants, Toxic; Valerates; Valine | 1968 |
The distribution of amino acids between erythrocytes and plasma in fetal and maternal blood.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Plasma; Pregnancy; Serine; Threonine; Valine | 1968 |
[Thin-layer chromatographic diagnosis of phenylketonuria].
Topics: Chromatography, Thin Layer; Fluorometry; Humans; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1968 |
Elevation of serum transaminase activity for branched chain amino acids in dogs with experimental myocardial infarction.
Topics: Animals; Aspartate Aminotransferases; Dogs; Isoleucine; Leucine; Liver; Myocardial Infarction; Myocardium; Transaminases; Valine | 1968 |
Formation and occurrence of N-malonylphenylalanine and related compounds in plants.
Topics: Amino Acids; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Edible Grain; Esters; Infrared Rays; Isoleucine; Leucine; Malonates; Phenylalanine; Seeds; Spectrophotometry; Stereoisomerism; Tryptophan; Tyrosine; Valine | 1968 |
Amino acid constituents of stendomycin.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Arginine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Peptides; Proline; Spectrum Analysis; Threonine; Valine | 1968 |
Formation of O-ethylhomoserine by bacteria.
Topics: Bacillus; Bacteria; Brevibacterium; Chromatography, Paper; Corynebacterium; Isoleucine; Leucine; Mycobacterium; Nocardia; Serine; Streptomyces; Valine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
An acetohydroxy acid synthetase from Neurospora crassa.
Topics: 1-Propanol; Acetaldehyde; Enterobacter; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoleucine; Lactates; Leucine; Ligases; Neurospora; Pantothenic Acid; Pyruvates; Sulfates; Temperature; Thiamine Pyrophosphate; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
C-terminal analysis of histidinol dehydrogenase from Neurospora crassa.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Ascomycota; Carboxypeptidases; Glutamates; Hydrazines; Isoleucine; Leucine; Serine; Spectrophotometry; Valine | 1968 |
Threonine deaminase and acetolactate synthetase in Anabaena variabilis.
Topics: Amino Acids; Carbon Isotopes; Cell-Free System; Eukaryota; Hydro-Lyases; Hydrogen-Ion Concentration; Isoenzymes; Isoleucine; Leucine; Ligases; Pyruvates; Spectrophotometry; Ultrasonics; Valine | 1968 |
Rat intestinal dipeptidase activity during oral neomycin and gluten administration.
Topics: Alanine; Animals; Body Weight; Caseins; Depression, Chemical; Dietary Proteins; Dipeptidases; Female; Glutens; Glycine; Intestinal Mucosa; Intestine, Small; Isoleucine; Leucine; Neomycin; Rats; Spectrophotometry; Triticum; Valine | 1968 |
Control of haemoglobin synthesis: a difference in the size of the polysomes making alpha and beta chains.
Topics: Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Genetic Code; Hemoglobins; Isoleucine; Peptide Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Sucrose; Tritium; Valine | 1968 |
Differences in the amino acid compositions of allogeneic guinea pig transplantation antigens.
Topics: Alanine; Amino Acids; Animals; Antigens; Chromatography, Gel; Electrophoresis; Guinea Pigs; Isoleucine; Leucine; Lymphoid Tissue; Serine; Sound; Transplantation Immunology; Transplantation, Homologous; Ultrasonics; Valine | 1968 |
A sensitive hydroosmotic toad bladder assay. Affinity and intrinsic activity of neurohypophyseal peptides.
Topics: Alanine; Animals; Anura; Arginine; Biological Assay; Hydrogen-Ion Concentration; Isoleucine; Ornithine; Oxytocin; Peptides; Phenylalanine; Pituitary Hormones, Posterior; Theophylline; Time Factors; Tyrosine; Urinary Bladder; Valine; Vasopressins; Vasotocin; Water-Electrolyte Balance | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
The formation of propionylcarnitine in isolated rat liver mitochondria.
Topics: Adenine Nucleotides; Amino Acids; Aminobutyrates; Animals; Bicarbonates; Butyrates; Carbon Dioxide; Carbon Isotopes; Carnitine; Citrates; Citric Acid Cycle; Coenzyme A; Depression, Chemical; Isoleucine; Keto Acids; Ketoglutaric Acids; Male; Mitochondria, Liver; Propionates; Rats; Stimulation, Chemical; Succinates; Tritium; Valerates; Valine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
The protein-polysaccharide complex of bovine nasal cartilage. Studies on the molecular organisation.
Topics: Acetone; Amino Acids; Animals; Aspartic Acid; Cartilage; Cattle; Chondroitin; Ethanol; Hexosamines; Hydrochloric Acid; Isoleucine; Leucine; Molecular Weight; Nose; Osmotic Pressure; Peptides; Polysaccharides; Pyrrolidinones; Tyrosine; Ultracentrifugation; Uronic Acids; Valine; Xylose | 1968 |
Methionine and glycine levels in the liver of riboflavin deficient rats.
Topics: Alanine; Animals; Autoanalysis; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Phenylalanine; Rats; Riboflavin Deficiency; Tyrosine; Valine | 1968 |
Influence of protein digestion on plasma amino acid levels in sheep.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Digestion; Glutamates; Glycine; Histidine; Intestinal Mucosa; Isoleucine; Leucine; Lysine; Male; Phenylalanine; Proline; Sheep; Tyrosine; Valine | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
Biosynthesis of branched-chain amino acids in yeast: regulation of leucine biosynthesis in prototrophic and leucine auxotrophic strains.
Topics: Enzyme Repression; Isoleucine; Isomerases; Leucine; Ligases; Malates; Mutation; Oxidoreductases; Saccharomyces; Threonine; Valine | 1968 |
Formation of a complex between valine and intestinal mucosal lipid; its possible role in valine absorption.
Topics: Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Paper; Cyanides; Depression, Chemical; Dinitrophenols; Galactose; Intestinal Absorption; Intestinal Mucosa; Isoleucine; Leucine; Lipid Metabolism; Male; Methionine; Rats; Valine | 1968 |
Transaminases of branched-chain amino acids. V. Activity change in developing and regenerating rat liver.
Topics: Adrenalectomy; Aging; Animals; Chromatography, Ion Exchange; Female; Fetus; Hepatectomy; Isoleucine; Leucine; Liver; Liver Regeneration; Male; Rats; Transaminases; Valine | 1968 |
[Biochemical-genetic studies in maple syrup disease].
Topics: Genetics, Medical; Humans; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
[Strengthening the contractile function of the myocardium under the effects of several amino acids].
Topics: Amino Acids; Animals; Anura; Heart; Isoleucine; Kymography; Leucine; Lysine; Methionine; Methods; Muscle Contraction; Phenylalanine; Threonine; Tryptophan; Valine | 1968 |
The effect of essential amino acid deficiency on the sex-specific accumulation of a blood protein in female house-flies (Musca domestica L.).
Topics: Amino Acids; Animals; Arginine; Blood Proteins; Deficiency Diseases; Diet; Female; Histidine; Houseflies; Isoleucine; Leucine; Lysine; Milk; Phenylalanine; Reproduction; Sex Factors; Threonine; Tryptophan; Valine | 1968 |
Sequence of limiting amino acids in fish protein concentrate produced by isopropyl alcohol extraction of red hake (Urophycis chuss).
Topics: 1-Propanol; Amino Acids; Animals; Arginine; Body Weight; Feeding Behavior; Fish Products; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Nutritional Physiological Phenomena; Phenylalanine; Proteins; Rats; Threonine; Tryptophan; Valine | 1969 |
Effects of feedback modifiers on mutationally altered threonine deaminases of Rhodopseudomonas spheroides.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Feedback; Hydro-Lyases; Isoleucine; Kinetics; Molecular Biology; Mutation; Rhodopseudomonas; Serine; Threonine; Valine | 1969 |
Leucine transport by rat liver mitochondria in vitro.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Depression, Chemical; Diffusion; Ethylmaleimide; Extracellular Space; In Vitro Techniques; Inulin; Isoleucine; Kinetics; Leucine; Methionine; Mitochondria, Liver; Phosphates; Potassium; Rats; Sodium; Stimulation, Chemical; Temperature; Valine | 1969 |
[Modification of lipid metabolism with solvosterol].
Topics: Aged; Alanine; Arteriosclerosis; Cholesterol; Colorimetry; Glycine; Humans; Injections, Intramuscular; Isoleucine; Lipids; Lipoproteins; Male; Serine; Valine | 1969 |
Free amino acids of fetal brain. Influence of the branched chain amino acids.
Topics: Amino Acids; Animals; Brain; Female; Fetus; Isoleucine; Leucine; Maternal-Fetal Exchange; Pregnancy; Rats; Valine | 1969 |
Studies in a patient with methylmalonic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Diet; Dietary Proteins; Glycine; Humans; Infant; Infant, Newborn; Intellectual Disability; Isoleucine; Isomerases; Leucine; Male; Malonates; Valine; Vitamin B 12 | 1969 |
The biochemistry of long-chain, nonisoprenoid hydrocarbonss. II. The incorporation of acetate and the aliphatic chains of isoleucine and valine into fatty acids and hydrocarbon by Sarcina lutea in vivo.
Topics: Acetates; Carbon Isotopes; Fatty Acids; Hydrocarbons; Isoleucine; Lipids; Methionine; Models, Biological; Sarcina; Valine | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver.
Topics: Amino Acids; Animals; Arginine; Asparagine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Perfusion; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Tryptophan; Valine | 1969 |
Biosynthesis of branched-chain amino acids in yeast: regulation of synthesis of the enzymes of isoleucine and valine biosynthesis.
Topics: Enzyme Repression; Hydro-Lyases; Isoleucine; Leucine; Ligases; Molecular Biology; Oxidoreductases; Saccharomyces; Transaminases; Valine | 1969 |
Metabolites of Streptomyces noursei. IX. Formation of amides of branched chain fatty acids.
Topics: Amides; Carbon Isotopes; Fatty Acids; Isoleucine; Leucine; Peroxidases; Streptomyces; Valine | 1969 |
Pyrrolidonecarboxylyl peptidase: studies on the specificity of the enzyme.
Topics: Alanine; Chemical Phenomena; Chemistry; Dipeptides; Isoleucine; Leucine; Peptide Hydrolases; Phenylalanine; Proline; Pseudomonas; Pyrrolidinones; Stereoisomerism; Tyrosine; Valine | 1969 |
Multivalent repression of isoleucine- valine biosynthesis in Saccharomyces cerevisiae.
Topics: Culture Media; Enzyme Repression; Hydro-Lyases; Isoleucine; Isomerases; Leucine; Ligases; Saccharomyces; Threonine; Valine | 1969 |
The disulphide bridges of Yoshida tumor glycoprotein.
Topics: Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Cystine; Glycoproteins; Isoleucine; Mercaptoethanol; Neoplasms, Experimental; Rats; Sulfhydryl Compounds; Valine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Amino acid regulation of albumin synthesis.
Topics: Albumins; Amino Acids; Animals; Arginine; Carbon Isotopes; Electrophoresis; Fasting; Immunoelectrophoresis; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Methionine; Methods; Perfusion; Rabbits; Ribosomes; Threonine; Tryptophan; Urea; Valine | 1969 |
Frameshift mutations resulting in the changes of the same amino acid residue (140) in T4 bacteriophage lysozyme and in vivo codons for Trp, Tyr, Met, Val and Ile.
Topics: Amino Acid Sequence; Chromatography; Chymotrypsin; Coliphages; Genetic Code; Isoleucine; Methionine; Molecular Biology; Muramidase; Mutation; Trypsin; Tryptophan; Tyrosine; Valine | 1969 |
M aple syrup urine disease. A review with a report of an additional case.
Topics: Diet Therapy; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Valine | 1969 |
A colorimetric and isotopic assay of leucine aminotransferase.
Topics: Carbon Isotopes; Colorimetry; Hydrazines; Isoleucine; Kinetics; Leucine; Spectrophotometry; Transaminases; Ultraviolet Rays; Valine | 1969 |
L-threonine dehydratases of flowering parasitic and saprophytic plants.
Topics: Adenine Nucleotides; Aspartic Acid; Glutathione; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Plants; Threonine; Valine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Concerted inhibition and its reversal by end products of aspartate kinase in Brevibacterium flavum.
Topics: Ammonia; Aspartic Acid; Binding Sites; Brevibacterium; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Isoleucine; Kinetics; Lysine; Mathematics; Phosphotransferases; Proteins; Salts; Spectrophotometry; Sulfates; Threonine; Time Factors; Valine | 1969 |
Maple syrup urine disease metabolites studies in cerebellum cultures.
Topics: Animals; Animals, Newborn; Cerebellum; Culture Techniques; Humans; Isoleucine; Keto Acids; Leucine; Maple Syrup Urine Disease; Myelin Sheath; Neuroglia; Neurons; Rats; Time Factors; Valine | 1969 |
The effects of individual amino acids on the incorporation of labelled amino acids into proteins by brain homogenates.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Centrifugation; Female; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Spectrum Analysis; Threonine; Tyrosine; Valine | 1969 |
Identification of the amino acid replacements characterizing the allotypic forms of bovine carboxypeptidase A.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Biological Evolution; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Drug Stability; Genes; Glutamates; Hot Temperature; Isoleucine; Leucine; Peptides; Trypsin; Valine | 1969 |
A rapid and simple thin-layer chromatographic method for amino acids in blood.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood Protein Disorders; Cellulose; Chromatography, Paper; Chromatography, Thin Layer; Humans; Infant; Isoleucine; Leucine; Mass Screening; Methods; Time Factors; Tyrosine; Valine | 1969 |
[Relationship between the rat's need for leucine, isoleucine and valine].
Topics: Animal Nutritional Physiological Phenomena; Animals; Isoleucine; Leucine; Nutritional Requirements; Phenylalanine; Rats; Valine | 1969 |
Maple syrup urine disease. Four years' experience with dietary treatment of a case.
Topics: Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Prognosis; Time Factors; Valine | 1969 |
Inhibition of gluconeogenesis by alpha-oxo acids.
Topics: Alanine; Amino Acids; Animals; Benzoates; Cinnamates; Fumarates; Gluconeogenesis; Glucose; In Vitro Techniques; Isoleucine; Keto Acids; Kidney; Lactates; Methionine; Phenylacetates; Phenylpyruvic Acids; Rats; Salicylates; Valine | 1964 |
The dependence of the substrate specificity on the conformation of crystalline glutamate dehydrogenase.
Topics: Adenine Nucleotides; Alanine; Amino Acid Oxidoreductases; Aminobutyrates; Animals; Cattle; Chemical Phenomena; Chemistry; Diethylstilbestrol; Glutamate Dehydrogenase; Guanine Nucleotides; In Vitro Techniques; Isoleucine; Kinetics; Leucine; Liver; Methionine; Valine | 1965 |
The effects of test doses of leucine, isoleucine or valine on plasma amino acid levels. The unique effect of leucine.
Topics: Amino Acids; Blood; Fasting; Humans; Isoleucine; Leucine; Male; Obesity; Valine | 1965 |
Studies of the lipids of dog skin. 3. The in vivo incorporation of acetate, pyruvate, and certain amino acids into the lipids of isolated perfused dog skin.
Topics: Acetates; Alanine; Amino Acids; Animals; Carbon Isotopes; Chromatography, Thin Layer; Dogs; Isoleucine; Lipids; Perfusion; Pyruvates; Radiometry; Skin; Valine | 1965 |
Amino acid and alpha-keto acid concentrations in plasma and blood of the liverless dog.
Topics: Amino Acids; Aminobutyrates; Animals; Blood; Caproates; Chromatography, Paper; Dogs; Hepatectomy; Isoleucine; Keto Acids; Ketoglutaric Acids; Lactates; Leucine; Methionine; Pyruvates; Valerates; Valine | 1965 |
Substrate specificity of crystalline frog liver glutamate dehydrogenase.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Anura; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Glutamine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Ornithine; Valine | 1965 |
[RNA isolated from turnip yellow mosaic virus; acceptor of amino acids in the presence of bacterial enzymes].
Topics: Alanine; Alcaligenes; Amino Acids; Arginine; In Vitro Techniques; Isoleucine; Leucine; Nucleotides; Phenylalanine; Plant Viruses; Proline; RNA, Viral; Serine; Ultracentrifugation; Valine | 1965 |
Stimulation of protein synthesis in vitro by elevated levels of amino acids.
Topics: Amino Acids; Animals; Histidine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Protein Biosynthesis; Rats; Threonine; Valine | 1965 |
Effects of protein or amino acid deprivation on the tissue distribution of vitamin B12.
Topics: Amino Acids; Animals; Cobalt Isotopes; Cystine; Deficiency Diseases; Histidine; Isoleucine; Kidney; Leucine; Liver; Methionine; Nitrogen; Rats; Tryptophan; Urine; Valine; Vitamin B 12 | 1965 |
Stimulation of cell-free protein synthesis by homologous and heterologous messenger ribonucleic acid.
Topics: Animals; In Vitro Techniques; Isoleucine; Plant Viruses; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; RNA, Viral; Valine | 1965 |
Biosynthesis of valine and isoleucine in plants. 3. Reductoisomerase of Phaseolus radiatus.
Topics: Ascorbic Acid; Hydrogen-Ion Concentration; Hydroxybutyrates; In Vitro Techniques; Isoleucine; Isomerases; Kinetics; Lactates; Plants, Edible; Valine | 1965 |
Use of the stereoisomers of isoleucine by Lactobacillus fermenti.
Topics: Biological Assay; Culture Media; In Vitro Techniques; Isoleucine; Lactobacillus; Leucine; Pyridoxine; Valine | 1965 |
Further study of factors affecting amino acid incorporation into protein by isolated mitochondria.
Topics: Amino Acids; Animals; In Vitro Techniques; Isoleucine; Liver; Mitochondria; Oxygen; Protein Biosynthesis; Rats; Subcellular Fractions; Temperature; Valine | 1965 |
Comparative effects of glutamine analogues on protein metabolism of 6C3H-ED and Ehrlich ascites carcinoma.
Topics: Amides; Animals; Azaserine; Azides; Carcinoma, Ehrlich Tumor; Diazooxonorleucine; Glutamine; Hydroxamic Acids; In Vitro Techniques; Isoleucine; Lymphoma, Non-Hodgkin; Methionine; Methionine Sulfoximine; Neoplasm Proteins; Sarcoma, Experimental; Valine | 1965 |
Amino acid requirements of grain beetles.
Topics: Animals; Arginine; Bees; Biological Assay; Coleoptera; Dietary Proteins; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Nutritional Physiological Phenomena; Phenylalanine; Poultry; Rats; Threonine; Tryptophan; Valine | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Stimulation of insulin secretion by amino acids.
Topics: Adult; Amino Acids; Arginine; Blood Glucose; Fatty Acids; Female; Histidine; Humans; Hyperinsulinism; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1966 |
Effect of pyridoxine on the metabolism of tryptophan and branched-chain amino acids in two mentally retarded sibs.
Topics: Child, Preschool; Female; Humans; Intellectual Disability; Isoleucine; Leucine; Male; Pyridines; Pyridoxine; Tryptophan; Valine | 1966 |
Quantitative evaluation of the threonine, isoleucine, valine and phenylalanine needs of adult swine for maintenance.
Topics: Animals; Dietary Proteins; Isoleucine; Nitrogen; Phenylalanine; Swine; Threonine; Valine | 1966 |
Differentiation of dimethylaminonaphthalenesulphonic derivatives (DNS) of valine, leucine and isoleucine by chromatography on a thin layer of silica gel.
Topics: Chromatography, Thin Layer; Isoleucine; Leucine; Naphthalenes; Sulfonic Acids; Valine | 1966 |
Effect of leucine--isoleucine antagonism on the amino acid pattern of plasma and tissues of the rat.
Topics: Animals; Blood; Diet; In Vitro Techniques; Intestine, Small; Isoleucine; Leucine; Liver; Muscles; Rats; Subcellular Fractions; Valine | 1966 |
Postnatal changes in free amino acid pool of rat brain.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chromatography; Glutamates; Glutamine; Isoleucine; Leucine; Phenylalanine; Proline; Rats; Tyrosine; Valine | 1966 |
Transaminase of branched chain amino acids. I. Branched chain amino acids-alpha-ketoglutarate transaminase.
Topics: Animals; In Vitro Techniques; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Mercaptoethanol; Microsomes; Mitochondria; Muscles; Myocardium; Pyridoxal Phosphate; Rats; Subcellular Fractions; Swine; Transaminases; Valine | 1966 |
Effect of insulin, chlorpropamide and tolbutamide on the metabolism of branched chain amino acids.
Topics: Animals; Chlorpropamide; In Vitro Techniques; Insulin; Isoleucine; Leucine; Rabbits; Rats; Tolbutamide; Valine | 1966 |
Ornithine delta-transaminase activity during the growth cycle of Chang's liver cells.
Topics: Culture Techniques; Dactinomycin; Enzyme Repression; Isoleucine; Leucine; Liver; Ornithine; Transaminases; Valine | 1966 |
Purification and feedback control of threonine deaminase activity of Rhodopseudomonas spheroides.
Topics: Chromatography; Feedback; Hydro-Lyases; Isoleucine; Kinetics; Mercury; Pyridoxal Phosphate; Rhodopseudomonas; Threonine; Urea; Valine | 1966 |
Effect of different essential amino acid deficiencies on amino acid pools in rats.
Topics: Amino Acids; Animals; Isoleucine; Leucine; Liver; Male; Muscles; Rats; Threonine; Valine | 1966 |
Development of structure and function in the mammalian yolk sac. 3. The development of amino acid transport by rabbit yolk sac.
Topics: Alanine; Amino Acids; Animals; Betaine; Biological Transport; Carbon Isotopes; Female; Fetus; Glycine; Glycosides; In Vitro Techniques; Inulin; Isoleucine; Lysine; Maternal-Fetal Exchange; Methionine; Phenylalanine; Placenta; Pregnancy; Pregnancy, Animal; Proline; Quaternary Ammonium Compounds; Rabbits; Valine | 1966 |
Interference between leucine, isoleucine and valine during intestinal absorption.
Topics: Amino Acids; Animals; In Vitro Techniques; Intestinal Absorption; Isoleucine; Leucine; Rats; Valine | 1966 |
The assembly of ribosomes in HeLa cells.
Topics: Carbon Isotopes; Culture Techniques; Cycloheximide; Electrophoresis; HeLa Cells; Isoleucine; Kinetics; Leucine; Peptide Biosynthesis; Protein Biosynthesis; Ribosomes; RNA; Tritium; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
The preparation of pure [I-14-C]- and [I-3-H]-labeled L-amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Carbon Isotopes; Chemistry, Organic; Chromatography; Glycine; Isoleucine; Leucine; Optics and Photonics; Organic Chemistry Phenomena; Phenylalanine; Tritium; Tyrosine; Valine | 1966 |
[Maple syrup urine disease. (Valine-leucine-uria)].
Topics: Child; Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1966 |
[The liver as a regulatory organ for the plasma concentration of free amino acids. (Studies on the isolated perfused rat liver)].
Topics: Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; Isoleucine; Leucine; Liver; Perfusion; Proline; Rats; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Formation of toxic substances by fungi in the degradation of some amino acids.
Topics: Amino Acids; Aspergillus; Fungi; Isoleucine; Leucine; Mitosporic Fungi; Penicillium; Valine | 1966 |
The therapy of maple syrup urine disease.
Topics: Child; Child, Preschool; Diet Therapy; Female; Growth; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Methionine; Neurologic Manifestations; Valine | 1967 |
Isovaleric acidemia.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Chromatography, Gas; Fatty Acids; Female; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Male; Valine | 1967 |
Free amino acids in liver, plasma, and muscle of patients with cirrhosis of the liver.
Topics: Amino Acids; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Muscles; Nitrogen; Phenylalanine; Threonine; Valine; Water | 1967 |
Biochemical and genetic analysis of isoleucine and valine biosynthesis in Staphylococcus aureus.
Topics: Genetics; Hydroxybutyrates; Isoleucine; Lactates; Molecular Biology; Mutation; Pyruvates; Salmonella; Staphylococcus; Threonine; Valerates; Valine | 1967 |
Hyperglycinemia with ketoacidosis and leukopenia. Metabolic studies on the nature of the defect.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Diet Therapy; Dietary Proteins; Glycine; Humans; Infant; Isoleucine; Leucine; Leukopenia; Lysine; Male; Valine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Inhibition of the oxidation of leucine by hypoglycin.
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; In Vitro Techniques; Isoleucine; Leucine; Liver; Male; Rats; Valine | 1967 |
Influence of isoleucine upon quinomycin biosynthesis by Streptomyces sp. 732.
Topics: Anti-Bacterial Agents; Chromatography, Paper; Isoleucine; Leucine; Methionine; Streptomyces; Threonine; Tryptophan; Valine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Further evidence for two distinct acetolactate synthetases in Aerobacter aerogenes.
Topics: Enterobacter; Hydrogen-Ion Concentration; Isoleucine; Lactates; Ligases; Mutation; Nitroso Compounds; Valine | 1967 |
Plasma amino acid pattern of chicks in relation to length of feeding period.
Topics: Amino Acids; Animals; Appetite Regulation; Arginine; Birds; Cystine; Dietary Proteins; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Effect of fasting and of feeding a nonprotein diet on plasma amino acid levels in the chick.
Topics: Amino Acids; Animals; Arginine; Birds; Cystine; Diet; Dietary Proteins; Fasting; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Effects of excess leucine on growth and food selection.
Topics: Amino Acids; Animals; Body Weight; Diet; Dietary Proteins; Eating; Growth; Isoleucine; Leucine; Male; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Valine | 1967 |
Thiamine-dependent accumulation of tetramethylpyrazine accompanying a mutation in the isoleucine-valine pathway.
Topics: Corynebacterium; Culture Media; Isoleucine; Magnetic Resonance Spectroscopy; Mutation; Pyrazines; Thiamine; Valine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Synthesis of chicken hemoglobins during erythrocyte differentiation.
Topics: Animals; Autoradiography; Cell Differentiation; Centrifugation, Density Gradient; Chickens; Erythrocytes; Hemoglobins; In Vitro Techniques; Isoleucine; Kinetics; Leucine; Phenylhydrazines; Serum Albumin, Bovine; Tritium; Tyrosine; Uridine; Valine | 1967 |
Structural basis of kanamycin for miscoding activity.
Topics: Adenine Nucleotides; Amines; Amino Acids; Amino Sugars; Arginine; Chemical Phenomena; Chemistry; Cytosine Nucleotides; DNA; Genetic Code; Isoleucine; Kanamycin; Leucine; Lysine; Phenylalanine; Polynucleotides; Proline; Serine; Threonine; Uracil Nucleotides; Valine | 1967 |
Biosynthesis of long-chain hydrocarbons. I. Incorporation of L-valine, L-threonine, L-isoleucine, and L-leucine into specific branched-chain hydrocarbons in tobacco.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gas; Hydrocarbons; Isoleucine; Leucine; Nicotiana; Plants, Toxic; Spectrophotometry; Spectrum Analysis; Threonine; Valine | 1967 |
Induced phenotypic resistance to valine in Mycobacterium pellegrino.
Topics: Enzyme Repression; Hydro-Lyases; Isoleucine; Leucine; Ligases; Mycobacterium; Valine | 1967 |
Serum amino acid concentrations in alcoholic hepatitis.
Topics: Alcoholism; Amino Acids; Chromatography, Paper; Glutamates; Hepatectomy; Hepatitis; Humans; Isoleucine; Kwashiorkor; Leucine; Protein Deficiency; Valine | 1967 |
Maple syrup urine disease in an infant with microgyria.
Topics: Brain; Cerebral Cortex; Chromatography, Paper; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Pons; Spasm; Thalamus; Valine | 1967 |
Lack of specificity of isoleucyl-tRNA synthetase: evidence for anomalous charging of tRNA.
Topics: Bacillus; Carbon Isotopes; Catalysis; Chromatography; Isoleucine; Ligases; RNA, Bacterial; RNA, Transfer; Serine; Temperature; Threonine; Valine | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
Hypervalinemia. A defect in valine transamination.
Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Carbon Isotopes; Child, Preschool; Female; Fetal Diseases; Humans; Intellectual Disability; Isoleucine; Japan; Keto Acids; Leucine; Leukocytes; Methionine; Phenylalanine; Placenta; Pregnancy; Transaminases; Valine | 1967 |
Effect of valine, leucine, and isoleucine on the production of fly toxin by bacillus thuringiensis and related organisms.
Topics: Animals; Bacillus; Biological Assay; Diptera; Isoleucine; Leucine; Toxins, Biological; Valine | 1967 |
Metabolic precursors of methylmalonic acid in vitamin B12 deficiency.
Topics: Humans; Isoleucine; Malonates; Propionates; Stimulation, Chemical; Valine; Vitamin B 12 Deficiency | 1967 |
[Transamination between amino acids and alpha-ketoglutaric acid in the carp].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cyprinidae; Glutamates; In Vitro Techniques; Intestinal Mucosa; Isoleucine; Ketoglutaric Acids; Leucine; Liver; Lysine; Ornithine; Perfusion; Phenylalanine; Transaminases; Tyrosine; Valine | 1967 |
Free amino acids, ammonia and urea concentrations in the blood plasma of starved lambs.
Topics: Age Factors; Alanine; Amino Acids; Ammonia; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Glutamates; Isoleucine; Leucine; Lysine; Sheep; Starvation; Threonine; Urea; Valine | 1967 |
Effects of valine, leucine, and isoleucine on the growth of Bacillus thuringiensis and related bacteria.
Topics: Bacillus; Isoleucine; Leucine; Valine | 1967 |
Regulation of Salmonella typhimurium ilvYC genes.
Topics: Base Sequence; Chromosome Deletion; Cloning, Molecular; DNA Restriction Enzymes; DNA, Recombinant; Escherichia coli; Gene Expression Regulation; Genes; Genes, Bacterial; Genotype; Isoleucine; Plasmids; Salmonella typhimurium; Transcription, Genetic; Valine | 1984 |
The need of essential amino acids in children. An evaluation based on the intake of phenylalanine, tyrosine, leucine, isoleucine, and valine in children with phenylketonuria, tyrosine amino transferase defect, and maple syrup urine disease.
Topics: Amino Acids, Essential; Child; Child, Preschool; Dietary Proteins; Female; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Nutritional Requirements; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Tyrosine; Tyrosine Transaminase; Valine | 1980 |
Effects of excess leucine on growth and tryptophan and niacin metabolism in rats.
Topics: Animals; Body Weight; Diet; Erythrocytes; Female; Hydroxyindoleacetic Acid; Isoleucine; Leucine; NAD; NADP; Nicotinic Acids; Organ Size; Pellagra; Quinolinic Acids; Rats; Time Factors; Tryptophan; Valine; Vitamin B 6 Deficiency | 1980 |
Adsorption of protein and non-protein amino acids on a clay mineral: a possible role of selection in chemical evolution.
Topics: Adsorption; Alanine; Amino Acids; Bentonite; Biological Evolution; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Glycine; Hydrogen-Ion Concentration; Isoleucine; Sarcosine; Valine | 1980 |
Determination of the total rates of synthesis and degradation of RNA in a bacterial culture.
Topics: Chloramphenicol; DNA, Bacterial; Escherichia coli; Isoleucine; Models, Biological; RNA, Bacterial; Valine | 1981 |
Molecular cloning and expression of the ilvGEDAY genes from Salmonella typhimurium.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Gene Expression Regulation; Isoleucine; Operon; RNA, Bacterial; RNA, Ribosomal; Salmonella typhimurium; Valine | 1981 |
Polyamine regulation of stringent control in a polyamine-auxotrophic strain of Escherichia coli.
Topics: Escherichia coli; Guanosine Pentaphosphate; Guanosine Tetraphosphate; Isoleucine; Mutation; Putrescine; RNA, Bacterial; Spermidine; Valine | 1984 |
Identification of a protein of 15,000 daltons related to isoleucine-valine biosynthesis in Escherichia coli K-12.
Topics: Bacterial Proteins; Bacteriophage lambda; Escherichia coli; Genes, Bacterial; Isoleucine; Molecular Weight; Mutation; Plasmids; Recombination, Genetic; Species Specificity; Valine | 1982 |
Molecular characterization of ilvC specialized transducing phages of Escherichia coli K-12.
Topics: Adenylyl Cyclases; Bacteriophage lambda; Defective Viruses; DNA, Bacterial; Escherichia coli; Genes; Genes, Regulator; Genetic Linkage; Isoleucine; Operon; Transduction, Genetic; Valine | 1983 |
Isolation and analysis of two Escherichia coli K-12 ilv attenuator deletion mutants with high-level constitutive expression of an ilv-lac fusion operon.
Topics: Bacteriophage lambda; Base Sequence; beta-Alanine; Chromosome Deletion; Cloning, Molecular; DNA, Recombinant; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Genes, Regulator; Isoleucine; Lac Operon; Lysogeny; Mutation; Operon; Valine | 1984 |
The isolation of lambda phage carrying DNA from the histidine and isoleucine-valine regions of the Bacillus subtilis chromosome.
Topics: Bacillus subtilis; Bacteriophage lambda; Chromosomes, Bacterial; Cloning, Molecular; DNA, Viral; Histidine; Isoleucine; Transduction, Genetic; Valine | 1984 |
Salmonella typhimurium mutants defective in acetohydroxy acid synthases I and II.
Topics: Acetolactate Synthase; DNA Transposable Elements; Genes; Isoleucine; Mutation; Oxo-Acid-Lyases; Salmonella typhimurium; Transduction, Genetic; Valine | 1980 |
Location of the multivalent control site for the ilvEDA operon of Escherichia coli.
Topics: beta-Galactosidase; Coliphages; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Hydro-Lyases; Isoleucine; Nucleic Acid Heteroduplexes; Operon; Threonine Dehydratase; Transaminases; Transduction, Genetic; Valine | 1980 |
Regulation of ilvEDA expression occurs upstream of ilvG in Escherichia coli: additional evidence for an ilvGEDA operon.
Topics: DNA Transposable Elements; DNA-Directed RNA Polymerases; Escherichia coli; Gene Expression Regulation; Isoleucine; Operon; Plasmids; Valine | 1980 |
Identification of amino-acid substitutions in the proteolipid subunit of the ATP synthase from dicyclohexylcarbodiimide-resistant mutants of Escherichia coli.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Sequence; ATP Synthetase Complexes; Carbodiimides; Dicyclohexylcarbodiimide; Drug Resistance, Microbial; Escherichia coli; Isoleucine; Multienzyme Complexes; Mutation; Phosphotransferases; Proteolipids; Threonine; Valine | 1980 |
Adenosine 5'-triphosphate- yielding pathways of branched-chain amino acid fermentation by a marine spirochete.
Topics: Acetates; Acetic Acid; Acyltransferases; Adenosine Triphosphate; Anaerobiosis; Fermentation; Isoleucine; Leucine; Phosphotransferases; Seawater; Spirochaetales; Transaminases; Valine | 1981 |
Physical and genetic localization of ilv regulatory sites in lambda ilv bacteriophages.
Topics: Amino Acids, Branched-Chain; Bacteriophage lambda; DNA Restriction Enzymes; Genes, Bacterial; Genes, Regulator; Genes, Viral; Isoleucine; Leucine; Nucleic Acid Heteroduplexes; Operon; Transduction, Genetic; Valine | 1982 |
Relative map location of the rep and rho genes of Escherichia coli.
Topics: Bacterial Proteins; Chromosome Mapping; Chromosomes, Bacterial; DNA Helicases; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Isoleucine; Leucine; Rho Factor; Transcription Factors; Transduction, Genetic; Valine | 1982 |
E.S.R. of spin-trapped radicals in gamma-irradiated polycrystalline amino acids. Chromatographic separation of radicals.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Deamination; Electron Spin Resonance Spectroscopy; Free Radicals; Gamma Rays; Isoleucine; Leucine; Proline; Valine | 1982 |
Transcriptional activity of the transposable element Tn10 in the Salmonella typhimurium ilvGEDA operon.
Topics: Base Sequence; DNA Transposable Elements; DNA, Recombinant; Gene Expression Regulation; Isoleucine; Operon; Plasmids; Salmonella typhimurium; Transcription, Genetic; Valine | 1982 |
Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP.
Topics: Base Sequence; Cyclic AMP; Escherichia coli; Gene Expression Regulation; Isoleucine; Nucleic Acid Conformation; Operon; Receptors, Cyclic AMP; Structure-Activity Relationship; Transcription, Genetic; Valine | 1982 |
Role of alanine-valine transaminase in Salmonella typhimurium and analysis of an avtA::Tn5 mutant.
Topics: Culture Media; DNA Transposable Elements; Enzyme Repression; Genes, Bacterial; Isoleucine; Leucine; Mutation; Salmonella typhimurium; Transaminases; Valine | 1983 |
Regulation of acetohydroxy acid synthase activities in adenyl cyclase-deficient strains of Escherichia coli K-12.
Topics: Acetolactate Synthase; Adenylyl Cyclases; Cyclic AMP; Escherichia coli; Gene Expression Regulation; Guanosine Tetraphosphate; Isoleucine; Operon; Oxo-Acid-Lyases; Valine | 1983 |
Metabolism of branched-chain amino acids in dogs with Escherichia coli endotoxin shock.
Topics: Amino Acids, Branched-Chain; Animals; Blood Pressure; Dogs; Endotoxins; Escherichia coli Infections; Injections, Intravenous; Isoleucine; Leucine; Phenylalanine; Shock, Septic; Valine | 1983 |
Effect of experimental diabetes on the levels of aromatic and branched-chain amino acids in rat blood and brain.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood-Brain Barrier; Brain; Diabetes Mellitus, Experimental; Dietary Proteins; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1983 |
Isoleucyl-tRNA synthetase from Baker's yeast. Catalytic mechanism, 2',3'-specificity and fidelity in aminoacylation of tRNAIle with isoleucine and valine investigated with initial-rate kinetics using analogs of tRNA, ATP and amino acids.
Topics: Amino Acyl-tRNA Synthetases; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Models, Chemical; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Substrate Specificity; Valine | 1983 |
Influence of insulin on blood levels of branched chain keto and amino acids in man.
Topics: Adult; Amino Acids, Branched-Chain; Blood Glucose; Female; Hemiterpenes; Hormones; Humans; Insulin; Isoleucine; Keto Acids; Leucine; Male; Valine | 1983 |
Reduced expression of the isoleucine and valine enzymes in integration host factor mutants of Escherichia coli.
Topics: Acetolactate Synthase; Escherichia coli; Gene Expression Regulation; Integrases; Isoleucine; Mutation; Valine; Viral Proteins | 1984 |
[3H-thymidine incorporation following isoleucine limitation in stringent and relaxed controlled strains of Escherichia coli].
Topics: Chloramphenicol; DNA, Bacterial; Escherichia coli; Guanosine Tetraphosphate; Isoleucine; Thymidine; Tritium; Valine | 1984 |
Lithium-induced changes in plasma amino acid levels during treatment of affective disorders.
Topics: Amino Acids; Bipolar Disorder; Female; Humans; Isoleucine; Leucine; Lithium; Lithium Carbonate; Lysine; Male; Valine | 1983 |
Evidence that repression mechanisms can exert control over the thr, leu, and ilv operons of Escherichia coli K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genotype; Isoleucine; Leucine; Mutation; Operon; Species Specificity; Threonine; Valine | 1983 |
[Effect of a second limiting amino acid on protein utilization].
Topics: Amino Acids, Essential; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Dietary Proteins; Histidine; Isoleucine; Nutritional Requirements; Rats; Threonine; Valine | 1983 |
[Kinetic and allosteric properties of highly-purified, biosynthetic L-threonine dehydrogenase from brewer's yeast Saccharomyces carlsbergensis].
Topics: Alcohol Oxidoreductases; Allosteric Regulation; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Saccharomyces; Serine; Substrate Specificity; Valine | 1984 |
Effects of branched chain amino acids on spontaneous growth hormone secretion in the baboon.
Topics: Amino Acids, Branched-Chain; Animals; Eating; Growth Hormone; Isoleucine; Leucine; Lysine; Male; Papio; Phenylalanine; Time Factors; Tyrosine; Valine | 1984 |
Influence of basic and branched chain amino acid interactions on the lysine and valine requirements of young turkeys.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animal Feed; Animals; Arginine; Body Weight; Energy Metabolism; Female; Isoleucine; Leucine; Lysine; Male; Nutritional Requirements; Sex Factors; Turkeys; Valine | 1984 |
Branched-chain amino acid transport in Streptococcus agalactiae.
Topics: Adenosine Triphosphatases; Biological Transport, Active; Glucose; Glycolysis; Isoleucine; Kinetics; Lactose; Leucine; Phosphorylation; Streptococcus agalactiae; Valine | 1980 |
Evidence for the site of lambda insertion in the ilv gene cluster of Escherichia coli K-12.
Topics: Attachment Sites, Microbiological; Bacteriophage lambda; Escherichia coli; Genes; Isoleucine; Lysogeny; Recombination, Genetic; Valine | 1981 |
Identification of the protein products of the rrnC, ilv, rho region of the Escherichia coli K-12 chromosome.
Topics: Bacterial Proteins; Bacteriophage lambda; Chromosome Mapping; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Isoleucine; Leucine; Mutation; Transduction, Genetic; Valine | 1981 |
Capillary gas chromatographic/mass spectrometric analysis of abnormal metabolites in hypoglycin-treated rat urine.
Topics: Adipates; Animals; Cyclopropanes; Dicarboxylic Acids; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronic Acid; Glucuronidase; Glycine; Hydroxy Acids; Hypoglycins; Isoleucine; Male; Rats; Rats, Inbred Strains; Valerates; Valine | 1984 |
Precursor directed biosynthesis of paulomycins A and B. The effects of valine, isoleucine, isobutyric acid and 2-methylbutyric acid.
Topics: Anti-Bacterial Agents; Butyrates; Chromatography, High Pressure Liquid; Disaccharides; Fermentation; Isobutyrates; Isoleucine; Microbial Sensitivity Tests; Streptococcus; Valine | 1984 |
Leucine and isoleucine requirements of the kitten.
Topics: Animals; Body Weight; Cats; Diet; Female; Isoleucine; Leucine; Male; Nitrogen; Nutritional Requirements; Valine | 1984 |
Metabolism of valine and 3-methyl-2-oxobutanoate by the isolated perfused rat kidney.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Hemiterpenes; In Vitro Techniques; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kidney; Leucine; Male; Multienzyme Complexes; Oxidation-Reduction; Perfusion; Rats; Valine | 1984 |
Transport of branched-chain amino acids in brain slices of developing and adult rats.
Topics: Aging; Amino Acids; Amino Acids, Branched-Chain; Animals; Biological Transport; Brain; Extracellular Space; gamma-Aminobutyric Acid; In Vitro Techniques; Isoleucine; Leucine; Rats; Rats, Inbred Strains; Valine | 1984 |
Branched-chain amino acid metabolism in chronic renal failure.
Topics: Adult; Aged; Brain; Female; Humans; Isoleucine; Kidney; Kidney Failure, Chronic; Leg; Leucine; Male; Middle Aged; Splanchnic Circulation; Valine | 1983 |
Free amino-acid composition of wax-stimulated whole saliva in human subjects with healthy periodontium, severe chronic periodontitis and post-juvenile periodontitis.
Topics: Adult; Amino Acids; Amino Acids, Neutral; Chromatography, Gas; Female; Glycine; Humans; Isoleucine; Male; Periodontitis; Proline; Saliva; Valine | 1984 |
Plasma amino acid ratio as an index of hepatocellular maturity in the neonate.
Topics: Amino Acids; Cholestasis; Female; Humans; Infant Food; Infant, Low Birth Weight; Infant, Newborn; Isoleucine; Leucine; Liver; Male; Phenylalanine; Tyrosine; Valine | 1983 |
Complexes of polyadenylic acid and the methyl esters of amino acids.
Topics: Amino Acids; Esters; Genetic Code; Glycine; History, 16th Century; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Phenylalanine; Poly A; Spectrophotometry, Ultraviolet; Valine | 1983 |
Study on established lymphoid cells in maple syrup urine disease. Correlation with clinical heterogeneity.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Cell Division; Cell Line; Culture Media; Humans; Isoleucine; Ketone Oxidoreductases; Leucine; Lymphocytes; Maple Syrup Urine Disease; Multienzyme Complexes; Substrate Specificity; Valine | 1984 |
Leucine, isoleucine and valine requirements of immature beagle dogs.
Topics: Animals; Diet; Dogs; Dose-Response Relationship, Drug; Energy Intake; Growth; Isoleucine; Leucine; Male; Nitrogen; Nutritional Requirements; Urea; Valine | 1984 |
The valine, leucine and isoleucine requirements of white Leghorn chicks.
Topics: Animals; Body Weight; Chickens; Isoleucine; Leucine; Male; Nitrogen; Nutritional Requirements; Valine | 1984 |
Free tyrosine levels of rat brain and tissues with sympathetic innervation following administration of L-tyrosine in the presence and absence of large neutral amino acids.
Topics: Adipose Tissue, Brown; Adrenal Glands; Amino Acids; Animals; Brain; Isoleucine; Kidney; Kinetics; Leucine; Male; Myocardium; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tyrosine; Valine | 1984 |
Valine metabolism in vivo: effects of high dietary levels of leucine and isoleucine.
Topics: Amino Acids, Branched-Chain; Animals; Diet; Isoleucine; Keto Acids; Leucine; Male; Oxidation-Reduction; Rats; Valine | 1984 |
Guanosine pentaphosphate and guanosine tetraphosphate accumulation and induction of Myxococcus xanthus fruiting body development.
Topics: Amino Acids; Guanosine Pentaphosphate; Guanosine Tetraphosphate; Isoleucine; Leucine; Myxococcales; Threonine; Valine | 1980 |
Muscle and plasma amino acids after injury: hypocaloric glucose vs. amino acid infusion.
Topics: Amino Acids; Female; Glucose; Hip Joint; Hip Prosthesis; Humans; Isoleucine; Leucine; Male; Middle Aged; Muscles; Parenteral Nutrition; Phenylalanine; Surgical Procedures, Operative; Tyrosine; Valine; Wounds and Injuries | 1980 |
Absence of acetohydroxy acid synthetase in a clinical isolate of Neisseria gonorrhoeae requiring isoleucine and valine.
Topics: Acetolactate Synthase; Culture Media; Isoleucine; Neisseria gonorrhoeae; Oxo-Acid-Lyases; Threonine Dehydratase; Valine | 1980 |
Effect of dietary essential amino acid limitations upon native levels of murine serum immunoglobulins, transferrin, and complement.
Topics: Amino Acids, Essential; Animals; Ascitic Fluid; Complement C3; Diet; Female; Immunoglobulins; Isoleucine; Leucine; Lysine; Male; Mice; Serum Albumin; Transferrin; Valine | 1980 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Effects of amino acids on Thiobacillus acidophilus. II. Threonine deaminase.
Topics: Binding Sites; Isoleucine; Stereoisomerism; Thiobacillus; Threonine; Threonine Dehydratase; Valine | 1980 |
In vitro formation of beta-galactosidase with a template containing the lac genes fused to gene ilvD.
Topics: beta-Galactosidase; DNA, Recombinant; Escherichia coli; Fatty Acids; Galactosidases; Guanosine Tetraphosphate; Isoleucine; Mupirocin; Operon; Valine | 1980 |
Septic autocannibalism. A failure of exogenous nutritional support.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Female; Humans; Isoleucine; Male; Muscles; Parenteral Nutrition; Sepsis; Valine | 1980 |
[Regulation of the biosynthesis of branched aminoacyl tRNA synthetases in Bacillus cereus T].
Topics: Amino Acyl-tRNA Synthetases; Bacillus cereus; Isoleucine; Isoleucine-tRNA Ligase; Leucine; Leucine-tRNA Ligase; Threonine Dehydratase; Valine; Valine-tRNA Ligase | 1980 |
Mutations in the ilvY gene of Escherichia coli K-12 that cause constitutive expression of ilvC.
Topics: 2-Acetolactate Mutase; beta-Galactosidase; DNA, Recombinant; Escherichia coli; Genes; Isoleucine; Mutation; Operon; Valine | 1981 |
Alteration in plasma amino acid concentrations following subtotal hepatectomy in dogs.
Topics: Amino Acids; Animals; Dogs; Female; Hepatectomy; Hepatic Encephalopathy; Isoleucine; Leucine; Male; Methionine; Phenylalanine; Threonine; Tyrosine; Valine | 1981 |
pH and temperature effects on the molecular conformation of the porcine pancreatic secretory trypsin inhibitor as detected by hydrogen-1 nuclear magnetic resonance.
Topics: Alanine; Animals; Cattle; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Magnetic Resonance Spectroscopy; Protein Conformation; Structure-Activity Relationship; Temperature; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1982 |
Specialized transduction of the ilvD-thyB-ilvA region mediated by Bacillus subtilis bacteriophage SP beta.
Topics: Attachment Sites, Microbiological; Bacillus subtilis; Bacteriophages; Genes, Bacterial; Isoleucine; Leucine; Lysogeny; Recombination, Genetic; Thymine Nucleotides; Transduction, Genetic; Valine | 1982 |
Trypanosomatidae: isoleucine requirement and threonine deaminase in species with and without endosymbionts.
Topics: Animals; Bacteria; Bacterial Physiological Phenomena; Crithidia; Eukaryota; Isoleucine; Leishmania; Leucine; Symbiosis; Threonine; Threonine Dehydratase; Trypanosoma cruzi; Valine | 1982 |
Mutational separation of transport systems for branched-chain amino acids in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acids, Branched-Chain; Biological Transport; Genes, Bacterial; Isoleucine; Leucine; Mutation; Pseudomonas aeruginosa; Sodium; Valine | 1982 |
Isolation and characterization of a Pseudomonas aeruginosa PAO mutant defective in the structural gene for the LIVAT-binding protein.
Topics: Alanine; Bacterial Proteins; Biological Transport; Carrier Proteins; Chromosome Mapping; Chromosomes, Bacterial; Genes; Genes, Bacterial; Isoleucine; Leucine; Pseudomonas aeruginosa; Threonine; Valine | 1982 |
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine | 1982 |
Insertion of bacteriophage SP beta into the citF gene of Bacillus subtilis and specialized transduction of the ilvBC-leu genes.
Topics: Bacillus subtilis; Bacteriophages; Chromosome Mapping; Chromosomes, Bacterial; Genes; Genes, Bacterial; Isoleucine; Leucine; Lysogeny; Succinate Dehydrogenase; Transduction, Genetic; Valine | 1982 |
Effect of l-valine and l-isoleucine on fatty acid composition of Streptomyces hygroscopicus and S. griseus.
Topics: Fatty Acids; Isoleucine; Mutation; Streptomyces; Streptomyces griseus; Valine | 1982 |
Diagnosis of organic acidemias by gas chromatography--mass spectrometry.
Topics: Acid-Base Imbalance; Gas Chromatography-Mass Spectrometry; Humans; Isoleucine; Leucine; Lysine; Metabolism, Inborn Errors; Tryptophan; Valine | 1981 |
Primary cultures from fetal rat brain incorporate [3H]-isoleucine and [3H]-valine into immunoprecipitable angiotensin II.
Topics: Angiotensin II; Animals; Brain; Cells, Cultured; Female; Fetus; Isoleucine; Kinetics; Pregnancy; Rats; Rats, Inbred Strains; Tritium; Valine | 1983 |
Cysteine toxicity for oral streptococci and effect of branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Culture Media; Cysteine; Isoleucine; Leucine; Mouth; Oxidation-Reduction; Streptococcus; Streptococcus mutans; Streptococcus sanguis; Valine | 1983 |
Purification and characterization of 2-methyl-branched chain acyl coenzyme A dehydrogenase, an enzyme involved in the isoleucine and valine metabolism, from rat liver mitochondria.
Topics: Amino Acids; Animals; Electron Transport; Flavin-Adenine Dinucleotide; Isoelectric Point; Isoleucine; Male; Mitochondria, Liver; Molecular Weight; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Substrate Specificity; Valine | 1983 |
Role of interchain interactions in the stabilization of the right-handed twist of beta-sheets.
Topics: Hydrogen Bonding; Isoleucine; Mathematics; Models, Molecular; Protein Conformation; Valine | 1983 |
Evaluation of the relative potency of individual competing amino acids to tryptophan transport in endogenously depressed patients.
Topics: Adult; Aged; Amino Acids; Binding, Competitive; Biological Transport; Depressive Disorder; Female; Humans; Isoleucine; Leucine; Middle Aged; Phenylalanine; Tryptophan; Tyrosine; Valine | 1980 |
[Funtional study of gene relA in the expression of amino acid operons. III. The effect of the allelic state of gene relA on the derepression of the threonine and isoleucine-valine operons of Escherichia coli K-12].
Topics: Alleles; Amino Acids; Escherichia coli; Genes; Homoserine Dehydrogenase; Isoleucine; Operon; Protein Biosynthesis; Threonine; Threonine Dehydratase; Transcription, Genetic; Valine | 1980 |
Analysis of yeast ilv 1 CIS control and domain mutants.
Topics: Base Sequence; DNA, Fungal; Genes; Genes, Regulator; Isoleucine; Mutation; Saccharomyces cerevisiae; Threonine Dehydratase; Valine | 1980 |
Mutations in genes cpxA and cpxB of Escherichia coli K-12 cause a defect in isoleucine and valine syntheses.
Topics: Acetolactate Synthase; Escherichia coli; Genes; Isoenzymes; Isoleucine; Leucine; Mutation; Oxo-Acid-Lyases; Temperature; Valine | 1980 |
Augmentation of glycogen synthesis under stringent control in Escherichia coli.
Topics: Arginine; Escherichia coli; Glycogen; Isoleucine; Kinetics; Mutation; Species Specificity; Temperature; Valine | 1980 |
Cysteine and growth inhibition of Escherichia coli: threonine deaminase as the target enzyme.
Topics: Cysteine; Escherichia coli; Isoleucine; Leucine; Threonine Dehydratase; Valine | 1981 |
Organization and regulation of the ilvGEDA operon in Salmonella typhimurium LT2.
Topics: Chromosome Mapping; Gene Expression Regulation; Genes; Isoleucine; Mutation; Operon; Salmonella typhimurium; Valine | 1981 |
Effect of dietary essential amino acid limitations upon the susceptibility to Salmonella typhimurium and the effect upon humoral and cellular immune responses in mice.
Topics: Amino Acids, Essential; Animals; Antibodies, Bacterial; Dietary Proteins; Female; Immunity, Cellular; Isoleucine; Leucine; Liver; Macrophages; Mice; Phagocytosis; Salmonella Infections; Salmonella typhimurium; Spleen; Vaccination; Valine | 1981 |
Acetohydroxy acid synthase isoenzymes of Escherichia coli K-12: a trans-acting regulatory locus of ilvHI gene expression.
Topics: Acetolactate Synthase; Escherichia coli; Gene Expression Regulation; Genes, Dominant; Genes, Regulator; Isoenzymes; Isoleucine; Leucine; Mutation; Oxo-Acid-Lyases; RNA, Messenger; RNA, Transfer, Amino Acyl; Valine | 1981 |
The stimulus-secretion coupling of amino acid-induced insulin release. Synergistic effects of L-glutamine and 2-keto acids upon insulin secretion.
Topics: Animals; Caproates; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Rats; Valine | 1981 |
Biosynthetic pathway of beta-methylnorleucine, an antimetabolite produced by Serratia marcescens.
Topics: Anti-Bacterial Agents; Antimetabolites; Isoleucine; Leucine; Mutation; Serratia marcescens; Transaminases; Valine | 1981 |
Gene cpxA is a new addition to the linkage map of Escherichia coli K-12.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes, Bacterial; Genetic Linkage; Isoleucine; Transduction, Genetic; Valine | 1982 |
Amino acids as in vitro secretogogues of avian pancreatic polypeptide (APP) and insulin from the chicken pancreas.
Topics: Amino Acids; Animals; Arginine; Chickens; Female; In Vitro Techniques; Insulin; Insulin Secretion; Isoleucine; Leucine; Pancreas; Pancreatic Polypeptide; Phenylalanine; Valine | 1982 |
Altered regulation of isoleucine-valine biosynthesis in a hisW mutant of Salmonella typhimurium.
Topics: Acetolactate Synthase; Enzyme Repression; Gene Expression Regulation; Hydro-Lyases; Isoleucine; Mutation; Salmonella typhimurium; Temperature; Valine | 1982 |
Mutations in genes cpxA and cpxB of Escherichia coli K-12 cause a defect in acetohydroxyacid synthase I function in vivo.
Topics: Acetolactate Synthase; Escherichia coli; Genes, Bacterial; Isoenzymes; Isoleucine; Mutation; Oxo-Acid-Lyases; Temperature; Valine | 1982 |
Genetic analysis of Candida albicans: identification of different isoleucine-valine, methionine, and arginine alleles by complementation.
Topics: Adenine; Alleles; Amino Acids; Arginine; Candida albicans; Crosses, Genetic; Genetic Complementation Test; Isoleucine; Methionine; Valine | 1982 |
High-performance liquid chromatographic separation of six essential amino acids and its use as an aid in the diagnosis of branched-chain ketoaciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Chromatography, High Pressure Liquid; Female; Humans; Infant, Newborn; Isoleucine; Keto Acids; Leucine; Peritoneal Dialysis; Phenylalanine; Time Factors; Valine | 1982 |
Involvement of food intake and amino acid catabolism in the branched-chain amino acid antagonism in chicks.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Chickens; Diet; Dose-Response Relationship, Drug; Growth; Isoleucine; Leucine; Male; Valine | 1982 |
Comparative utilization of the alpha-keto and D- and L-alpha-hydroxy analogs of leucine, isoleucine and valine by chicks and rats.
Topics: Animals; Caproates; Chickens; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Pentanoic Acids; Rats; Species Specificity; Structure-Activity Relationship; Valerates; Valine | 1982 |
Plasma amino acid concentrations during branched-chain amino acid infusions in stressed patients.
Topics: Abdomen; Adult; Amino Acids; Amino Acids, Branched-Chain; Female; Humans; Infusions, Parenteral; Isoleucine; Leucine; Male; Middle Aged; Postoperative Care; Stress, Physiological; Valine | 1982 |
Reduction of cerebrospinal fluid phenylalanine after oral administration of valine, isoleucine, and leucine.
Topics: Administration, Oral; Adult; Amino Acids, Branched-Chain; Child; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1982 |
Prospective study of maple-syrup-urine disease for the first four days of life.
Topics: Age Factors; Amino Acids, Branched-Chain; Female; Fetal Blood; Food, Formulated; Humans; Infant Food; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Valine | 1982 |
Blood and tissue branched-chain amino and alpha-keto acid concentrations: effect of diet, starvation, and disease.
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diet; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Rats; Starvation; Valine | 1981 |
Effect of pyrrolizidine alkaloid-induced hepatic disease on plasma amino acid patterns in the horse.
Topics: 2-Aminoadipic Acid; Amino Acids; Ammonia; Animals; Horse Diseases; Horses; Isoleucine; Leucine; Liver Diseases; Male; Phenylalanine; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Senecio; Tyrosine; Valine | 1980 |
Neutral amino acid transport during the cell cycle of cultured human lymphocytes.
Topics: Amino Acids, Branched-Chain; Biological Transport; Cell Cycle; Cell Wall; Cells, Cultured; Humans; Isoleucine; Leucine; Lymphocytes; Valine | 1981 |
Possible polypeptide synthesis following injection of balanced but incomplete amino acid mixes into lizards.
Topics: Amino Acids; Amino Acids, Essential; Animals; Arginine; Female; Fishes; Isoleucine; Lizards; Macromolecular Substances; Male; Methionine; Muscle Proteins; Peptide Biosynthesis; Valine | 1981 |
Plasma tryptophan and five other amino acids in depressed and normal subjects.
Topics: Amino Acids; Depressive Disorder; Female; Humans; Isoleucine; Leucine; Male; Phenylalanine; Psychiatric Status Rating Scales; Tryptophan; Tyrosine; Valine | 1981 |
Nitrogen-sparing mechanisms of singly administered branched-chain amino acids in the injured rat.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Female; Isoleucine; Laparotomy; Leucine; Liver; Muscles; Nitrogen; Rats; Valine; Wounds and Injuries | 1981 |
Pamamycin inhibits nucleoside and inorganic phosphate transport in Staphylococcus aureus.
Topics: Antifungal Agents; Biological Transport; Cell Membrane; Electron Transport; Isoleucine; Kinetics; Macrolides; Organic Chemicals; Phosphates; Staphylococcus aureus; Thymidine; Uridine; Valine | 1981 |
Blood-brain transport of tryptophan and phenylalanine: effect of portacaval shunt in dogs.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Dogs; Isoleucine; Leucine; Phenylalanine; Portacaval Shunt, Surgical; Tryptophan; Tyrosine; Valine | 1981 |
The biosynthesis of cyanogenic glucosides in Linum usitatissimum (linen flax) in vitro.
Topics: Carbon Radioisotopes; Chromatography, Gas; Glucosides; Glycosides; Isoleucine; Kinetics; Microsomes; Plants; Valine | 1981 |
Threonine, isoleucine, valine and leucine requirements of the young kitten.
Topics: Amino Acids; Animals; Cats; Isoleucine; Leucine; Nutritional Requirements; Threonine; Valine | 1980 |
Leucine, isoleucine, valine and histidine requirements of fingerling channel catfish.
Topics: Amino Acids, Essential; Animals; Body Weight; Carnosine; Dose-Response Relationship, Drug; Fishes; Histidine; Isoleucine; Leucine; Nutritional Requirements; Valine | 1980 |
Production of alanine and glutamine by atrial muscle from fed and fasted rats.
Topics: Alanine; Amino Acids; Animals; Fasting; Glutamine; In Vitro Techniques; Isoleucine; Leucine; Male; Myocardium; Papillary Muscles; Rats; Valine | 1980 |
Tumor host relations. V. Nitrogen metabolism in Yoshida sarcoma-bearing rats. Reduction of growth rate and increase of survival time by administration of physiological doses of branched-chain amino acids.
Topics: Amino Acids; Animals; Body Weight; Eating; Female; Isoleucine; Ketoglutaric Acids; Leucine; Nitrogen; Rats; Sarcoma, Yoshida; Valine | 1980 |
Kinetics of cerebral uptake processes in vitro of L-glutamine, branched-chain L-amino acids, and L-phenylalanine: effects of ouabain.
Topics: Animals; Biological Transport; Cerebral Cortex; Diffusion; Glutamine; In Vitro Techniques; Isoleucine; Kinetics; Leucine; Male; Ouabain; Phenylalanine; Rats; Sodium; Valine | 1980 |
Thermostability and aliphatic index of globular proteins.
Topics: Alanine; Bacterial Proteins; Chemical Phenomena; Chemistry; Drug Stability; Geobacillus stearothermophilus; Hot Temperature; Isoleucine; Leucine; Statistics as Topic; Valine | 1980 |
Contribution of hydrophobic residues to the stability of human lysozyme: calorimetric studies and X-ray structural analysis of the five isoleucine to valine mutants.
Topics: Calorimetry, Differential Scanning; Crystallography, X-Ray; Humans; Isoleucine; Muramidase; Point Mutation; Protein Conformation; Solutions; Thermodynamics; Valine; Water | 1995 |
The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes.
Topics: Alanine; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; CD36 Antigens; Cell Line; Cytoplasm; Humans; Intracellular Membranes; Isoleucine; Leucine; Lysosomal Membrane Proteins; Lysosomes; Magnetic Resonance Spectroscopy; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Receptors, Scavenger; Sequence Deletion; Sialoglycoproteins; Transfection; Valine | 1994 |
Differential replication of plasmids during stringent and relaxed response of Escherichia coli.
Topics: Amino Acids; Arginine; DNA Replication; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Guanosine Tetraphosphate; Isoleucine; Plasmids; RNA, Bacterial; Valine | 1994 |
Heat shock protein HSP60 can alleviate the phenotype of mitochondrial RNA-deficient temperature-sensitive mna2 pet mutants.
Topics: Alanine; Alleles; Base Sequence; Blotting, Northern; Chaperonin 60; DNA Mutational Analysis; DNA, Fungal; Fungal Proteins; Genes, Fungal; Genetic Complementation Test; Isoleucine; Mitochondria; Molecular Sequence Data; Oxygen Consumption; Point Mutation; Restriction Mapping; RNA; RNA, Fungal; RNA, Mitochondrial; Saccharomyces cerevisiae; Temperature; Valine | 1995 |
Modulation of skeletal muscle protein synthesis by amino acids and insulin during sepsis.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Bacteremia; Insulin; Isoleucine; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA; Sepsis; Valine | 1995 |
Association of cigarette smoking and CYP1A1 polymorphisms with adenocarcinoma of the lung by grades of differentiation.
Topics: Adenocarcinoma; Aged; Case-Control Studies; Cell Differentiation; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; Female; Genotype; Humans; Isoenzymes; Isoleucine; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking; Valine | 1995 |
Changes in the ratio of branched-chain to aromatic amino acids affect the secretion of albumin in cultured rat hepatocytes.
Topics: Amino Acids, Branched-Chain; Animals; Cells, Cultured; Gene Expression; Isoleucine; Kinetics; Leucine; Liver; Male; Phenylalanine; Rats; Rats, Wistar; RNA, Messenger; Serum Albumin; Tyrosine; Valine | 1995 |
CYP1A1 and CYP2E1 polymorphism and lung cancer, case-control study in Rio de Janeiro, Brazil.
Topics: Base Sequence; Brazil; Case-Control Studies; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA Primers; Exons; Female; Humans; Isoleucine; Lung Neoplasms; Male; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Reference Values; Smoking; Urban Population; Valine | 1995 |
Detection of CYP1A1 gene polymorphism using designed RFLP and distributions of CYP1A1 genotypes in Japanese.
Topics: Adult; Aged; Base Sequence; Cytochrome P-450 Enzyme System; Female; Finland; Gene Frequency; Genotype; Humans; Isoleucine; Japan; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Valine | 1995 |
Combined malonic, methylmalonic and ethylmalonic acid semialdehyde dehydrogenase deficiencies: an inborn error of beta-alanine, L-valine and L-alloisoleucine metabolism?
Topics: Alanine; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Child; Fibroblasts; Humans; Hydroxybutyrate Dehydrogenase; Isoleucine; Male; Malonate-Semialdehyde Dehydrogenase (Acetylating); Methylmalonate-Semialdehyde Dehydrogenase (Acylating); Valine | 1993 |
A mixture of the branched chain amino acids leucine, isoleucine and valine increases ovulation rate in ewes when infused during the late luteal phase of the oestrous cycle: an effect that may be mediated by insulin.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Growth Hormone; Insulin; Isoleucine; Leucine; Luteal Phase; Luteinizing Hormone; Ovulation; Prolactin; Sheep; Valine | 1995 |
An expanded two-state model accounts for homotropic cooperativity in biosynthetic threonine deaminase from Escherichia coli.
Topics: Allosteric Regulation; Allosteric Site; Binding Sites; Calorimetry; Cloning, Molecular; Escherichia coli; Feedback; Isoleucine; Kinetics; Mathematics; Models, Theoretical; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Salmonella typhimurium; Substrate Specificity; Thermodynamics; Threonine; Threonine Dehydratase; Valine | 1995 |
Residues in a class I tRNA synthetase which determine selectivity of amino acid recognition in the context of tRNA.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cross-Linking Reagents; Escherichia coli; Humans; Isoleucine; Isoleucine-tRNA Ligase; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Sequence Homology, Amino Acid; Substrate Specificity; Valine | 1995 |
Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.
Topics: Amino Acid Sequence; Antibody Specificity; Arginine; Arthritis, Rheumatoid; Aspartic Acid; beta 2-Microglobulin; Chromatography, Affinity; Computers; Epitopes; Humans; Immunoglobulin A; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunoglobulin M; Isoleucine; Lysine; Molecular Sequence Data; Rheumatoid Factor; Sequence Homology, Amino Acid; Tryptophan; Valine | 1993 |
Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: glycine 22 to serine 22 and isoleucine 28 to valine 28.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Base Sequence; DNA Primers; Glycine; Humans; Isoleucine; Molecular Sequence Data; Mutation; Polymorphism, Single-Stranded Conformational; Receptors, Serotonin; Serine; Valine | 1995 |
A double mutant allele, csr1-4, of Arabidopsis thaliana encodes an acetolactate synthase with altered kinetics.
Topics: Acetolactate Synthase; Alleles; Arabidopsis; Isoleucine; Kinetics; Leucine; Mutation; Pyruvates; Pyruvic Acid; Valine | 1995 |
Tandem integration of multiple ILV5 copies and elevated transcription in polyploid yeast.
Topics: Genes, Fungal; Isoleucine; Saccharomyces cerevisiae; Transcription, Genetic; Valine | 1995 |
Selective use of L-valine and L-isoleucine for the biosynthesis of branched-chain fatty acids in rat skin.
Topics: Absorption; Alcohols; Amino Acids; Animal Feed; Animals; Body Weight; Fatty Acids; Isoleucine; Lipid Metabolism; Lipids; Male; Rats; Rats, Wistar; Skin; Stereoisomerism; Valine | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
L-leucine transport systems in Saccharomyces cerevisiae participation of GAP1, S1 and S2 transport systems.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Culture Media; Genes, Fungal; Isoleucine; Kinetics; Leucine; Membrane Transport Proteins; Saccharomyces cerevisiae; Stereoisomerism; Valine | 1994 |
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.
Topics: False Positive Reactions; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Neonatal Screening; Paper; Phenylalanine; Reference Values; Sensitivity and Specificity; Valine | 1995 |
Binding of high-molecular-mass kininogen to the Apple 1 domain of factor XI is mediated in part by Val64 and Ile77.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Computer Simulation; Factor XI; Glutamic Acid; Humans; Isoleucine; Kininogens; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Valine | 1994 |
Allosteric regulation of biosynthetic threonine deaminase from Escherichia coli: effects of isoleucine and valine on active-site ligand binding and catalysis.
Topics: Allosteric Regulation; Binding Sites; Catalysis; Escherichia coli; Isoleucine; Kinetics; Ligands; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry; Stereoisomerism; Threonine; Threonine Dehydratase; Valine | 1995 |
Channeling behavior and activity models for Escherichia coli K-12 acetohydroxy acid synthases at physiological substrate levels.
Topics: Acetolactate Synthase; Amino Acids; Butyrates; Computer Simulation; Escherichia coli; Isoenzymes; Isoleucine; Kinetics; Pyruvates; Valine | 1995 |
Critical side-chain interactions at a subunit interface in the Arc repressor dimer.
Topics: Alanine; Bacteriophage P22; Biophysical Phenomena; Biophysics; Circular Dichroism; Escherichia coli; Isoleucine; Models, Molecular; Molecular Structure; Mutagenesis, Insertional; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Repressor Proteins; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Valine; Viral Proteins; Viral Regulatory and Accessory Proteins | 1995 |
Amyloid polyneuropathy in two German-American families: a new transthyretin variant (Val 107).
Topics: Aged; Amyloid Neuropathies; Base Sequence; Carpal Tunnel Syndrome; Deoxyribonucleases, Type II Site-Specific; DNA Mutational Analysis; DNA Primers; Germany; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prealbumin; United States; Valine | 1994 |
Precursor role of branched-chain amino acids in the biosynthesis of iso and anteiso fatty acids in rat skin.
Topics: Amino Acids, Branched-Chain; Animals; Carbon Radioisotopes; Fatty Acids; Fatty Alcohols; Isoleucine; Keto Acids; Leucine; Lipids; Male; Rats; Rats, Wistar; Skin; Valine | 1994 |
Naturally occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties.
Topics: Base Sequence; Chromatography, Affinity; Enzyme Stability; Glutathione Transferase; Hot Temperature; Humans; Isoleucine; Molecular Sequence Data; Oligodeoxyribonucleotides; Substrate Specificity; Valine | 1994 |
Eurystatins A and B, new prolyl endopeptidase inhibitors. III. Fermentation and controlled biosynthesis of eurystatin analogs by Streptomyces eurythermus.
Topics: Amino Acids; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Culture Media; Fermentation; Isoleucine; Molecular Structure; Peptides, Cyclic; Phenylhydrazines; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Streptomyces; Valine | 1994 |
Cooperative binding of the feedback modifiers isoleucine and valine to biosynthetic threonine deaminase from Escherichia coli.
Topics: Binding Sites; Circular Dichroism; Energy Metabolism; Escherichia coli; Feedback; Fluorescence; Isoleucine; Kinetics; Pyridoxal Phosphate; Threonine Dehydratase; Valine | 1994 |
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
Topics: Adenoma; Alanine; Amino Acid Sequence; Base Sequence; Cell Line; Codon; Cyclic AMP; Gene Expression; Humans; Isoleucine; Molecular Sequence Data; Mutation; Receptors, Thyrotropin; Structure-Activity Relationship; Threonine; Thyroid Neoplasms; Transfection; Valine | 1994 |
Effects of valine, leucine, isoleucine, and a balanced amino acid solution on the seizure threshold to picrotoxin in rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Injections, Intraperitoneal; Isoleucine; Leucine; Male; Picrotoxin; Rats; Rats, Wistar; Seizures; Valine | 1994 |
Helix-forming tendencies of nonpolar amino acids predicted by Monte Carlo simulated annealing.
Topics: Alanine; Amino Acids; Computer Simulation; Glycine; Hydrogen Bonding; Isoleucine; Leucine; Methionine; Monte Carlo Method; Oligopeptides; Phenylalanine; Protein Folding; Protein Structure, Secondary; Thermodynamics; Valine | 1994 |
Transthyretin VAL107, a new variant associated with familial cardiac and neuropathic amyloidosis.
Topics: Amyloid Neuropathies; Amyloidosis; Base Sequence; Cardiomyopathies; DNA Mutational Analysis; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Prealbumin; Valine | 1994 |
Mutations in the gene for a tRNA that functions as a regulator of a transcriptional attenuator in Bacillus subtilis.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Bacillus subtilis; Base Sequence; DNA Primers; Gene Expression Regulation, Bacterial; Genes, Bacterial; Isoleucine; Leucine; Molecular Sequence Data; Operon; Point Mutation; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Transfer, Leu; Suppression, Genetic; Terminator Regions, Genetic; Transcription, Genetic; Valine | 1994 |
Low-molecular-mass human salivary mucin, MG2: structure and binding of Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Fimbriae, Bacterial; Glycopeptides; Humans; Isoleucine; Leucine; Molecular Sequence Data; Mucins; Oligosaccharides; Phenylalanine; Proline; Protein Binding; Pseudomonas aeruginosa; Salivary Proteins and Peptides; Trypsin; Valine | 1993 |
A new point mutation in the prion protein gene at codon 210 in Creutzfeldt-Jakob disease.
Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Base Sequence; Brain; Codon; Creutzfeldt-Jakob Syndrome; DNA; DNA Primers; Humans; Isoleucine; Middle Aged; Molecular Sequence Data; Nerve Tissue Proteins; Oligonucleotide Probes; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prions; PrPSc Proteins; Reference Values; Valine | 1993 |
Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor.
Topics: 3T3 Cells; Animals; Genes, Dominant; Insulin Receptor Substrate Proteins; Isoleucine; Mice; Mutation; Phosphoproteins; Phosphorylation; Receptor, Insulin; Transfection; Valine | 1994 |
Screening of amyloid precursor protein gene mutation (APP 717 Val-->Ile) in Swedish families with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Chromosomes, Human, Pair 21; Down Syndrome; Genetic Testing; Humans; Isoleucine; Middle Aged; Mutation; Polymerase Chain Reaction; Sweden; Valine | 1993 |
Acrodermatitis enteropathica-like cutaneous lesions in organic aciduria.
Topics: Acrodermatitis; Amino Acid Metabolism, Inborn Errors; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Methylmalonic Acid; Microscopy, Electron; Propionates; Skin; Valine | 1994 |
Absence of linkage disequilibrium at amyloid precursor protein gene locus in Japanese familial Alzheimer's disease with 717Val-->Ile mutation.
Topics: Alleles; Alzheimer Disease; Amyloid beta-Protein Precursor; Humans; Isoleucine; Japan; Linkage Disequilibrium; Mutation; Polymorphism, Genetic; Valine | 1993 |
Mutational isolation of a sieve for editing in a transfer RNA synthetase.
Topics: Adenosine Triphosphate; Binding Sites; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Mutation; Protein Structure, Secondary; RNA Editing; RNA, Transfer, Ile; Valine | 1994 |
Kittens choose a high leucine diet even when isoleucine and valine are the limiting amino acids.
Topics: Animals; Cats; Diet; Eating; Female; Food Preferences; Isoleucine; Leucine; Male; Nitrogen; Specific Pathogen-Free Organisms; Valine; Weight Gain | 1994 |
Interaction of ustiloxin A with bovine brain tubulin.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Cattle; Depsipeptides; Isoleucine; Molecular Sequence Data; Mycotoxins; Oligopeptides; Peptides, Cyclic; Structure-Activity Relationship; Tubulin; Valine; Vinblastine | 1994 |
Effects of administration of branched-chain amino acids vs. glucose during acute exercise in the rat.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Body Weight; Brain; Energy Metabolism; Gluconeogenesis; Glucose Solution, Hypertonic; Insulin; Isoleucine; Leucine; Male; Physical Endurance; Physical Exertion; Rats; Serotonin; Valine | 1994 |
Effects of intraperitoneal L-leucine, L-isoleucine, L-valine, and L-arginine on milk fat depression in early lactation cows.
Topics: Amino Acids; Animals; Arginine; Body Weight; Cattle; Fatty Acids; Fatty Acids, Volatile; Female; Infusions, Parenteral; Isoleucine; Lactation; Leucine; Lipid Metabolism; Milk; Rumen; Valine | 1994 |
Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2.
Topics: Amino Acid Sequence; Calorimetry, Differential Scanning; Cloning, Molecular; Escherichia coli; Guanidine; Guanidines; Isoleucine; Leucine; Models, Molecular; Models, Structural; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Restriction Mapping; Serine Proteinase Inhibitors; Solvents; Spectrometry, Fluorescence; Valine | 1993 |
Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor.
Topics: Amino Acid Sequence; Base Sequence; Cells, Cultured; Cloning, Molecular; Drug Resistance, Microbial; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Genes, pol; HIV Antigens; HIV Core Protein p24; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Isoleucine; Molecular Sequence Data; Oligopeptides; Point Mutation; Protein Processing, Post-Translational; Valine; Viral Proteins; Virulence | 1994 |
Acetohydroxy acid synthase and threonine deaminase activities, and the biosynthesis of isoleucine-leucine-valine in Streptococcus bovis.
Topics: Acetolactate Synthase; Butyrates; Isoleucine; Leucine; Streptococcus bovis; Threonine Dehydratase; Valine | 1993 |
Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population.
Topics: Adult; Aged; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Cytochrome P-450 Enzyme System; Disease Susceptibility; DNA-Cytosine Methylases; Dose-Response Relationship, Drug; Environmental Exposure; Enzyme Activation; Female; Genotype; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoleucine; Japan; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking; Valine | 1993 |
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine | 1993 |
Peripheral metabolism of branched-chain keto acids in patients with chronic renal failure.
Topics: Adult; Amino Acids, Branched-Chain; Bicarbonates; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Valine | 1993 |
Alpha-keto and alpha-hydroxy branched-chain acid interrelationships in normal humans.
Topics: Adult; Amino Acids, Branched-Chain; Dietary Proteins; Evaluation Studies as Topic; Fasting; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Mass Spectrometry; Oxidation-Reduction; Protein Binding; Time Factors; Valerates; Valine | 1993 |
An efficient approach to identify ilvA mutations reveals an amino-terminal catalytic domain in biosynthetic threonine deaminase from Escherichia coli.
Topics: Binding Sites; Chromosome Mapping; Escherichia coli; Genes, Bacterial; Isoleucine; Kinetics; Mutagenesis; Restriction Mapping; Structure-Activity Relationship; Threonine Dehydratase; Valine | 1993 |
Packing and hydrophobicity effects on protein folding and stability: effects of beta-branched amino acids, valine and isoleucine, on the formation and stability of two-stranded alpha-helical coiled coils/leucine zippers.
Topics: Amino Acid Sequence; DNA-Binding Proteins; Drug Design; Drug Stability; Isoleucine; Leucine Zippers; Molecular Sequence Data; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Proteins; Valine | 1993 |
Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Allosteric Regulation; Asparagine; Binding Sites; Histidine; Histidine Decarboxylase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Phenylalanine; Pyruvates; Pyruvic Acid; Recombinant Proteins; Tyrosine; Valine | 1993 |
Distribution of solvent molecules around apolar side-chains in protein crystals.
Topics: Alanine; Amino Acids; Crystallography; Isoleucine; Leucine; Phenylalanine; Proteins; Solubility; Valine; Water; X-Ray Diffraction | 1993 |
Influence of divalent cations in protein crystallization.
Topics: Bacterial Proteins; Cadmium; Carrier Proteins; Cations, Divalent; Crystallization; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Isoleucine; Leucine; Periplasmic Binding Proteins; Polyethylene Glycols; Valine | 1995 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene.
Topics: Adult; Analysis of Variance; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; Enzyme Induction; Humans; Isoleucine; Lymphocytes; Male; Middle Aged; Mutation; Phenotype; Polymorphism, Genetic; Sensitivity and Specificity; Valine | 1996 |
A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoleucine; Membrane Proteins; Mutagenesis, Site-Directed; Prostaglandin-Endoperoxide Synthases; Sheep; Structure-Activity Relationship; Valine | 1996 |
An isoleucine to valine substitution in Escherichia coli acyl carrier protein results in a functional protein of decreased molecular radius at elevated pH.
Topics: Acyl Carrier Protein; Amino Acid Sequence; Base Sequence; Chromatography, Gel; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Mass Spectrometry; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Valine | 1996 |
Proofreading in trans by an aminoacyl-tRNA synthetase: a model for single site editing by isoleucyl-tRNA synthetase.
Topics: Acylation; Adenosine Monophosphate; Binding Sites; Escherichia coli; Homocysteine; Isoleucine; Isoleucine-tRNA Ligase; Models, Chemical; Protein Biosynthesis; RNA, Transfer; Substrate Specificity; Sulfhydryl Compounds; Valine | 1996 |
A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis.
Topics: Amino Acid Sequence; Amyloidosis; Base Sequence; Biopolymers; Female; Genetic Carrier Screening; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Prealbumin; Valine | 1996 |
Functional site in alpha-lactalbumin encompasses a region corresponding to a subsite in lysozyme and parts of two adjacent flexible substructures.
Topics: Amino Acid Sequence; Conserved Sequence; DNA Primers; Glutamic Acid; Glutamine; Histidine; Isoleucine; Kinetics; Lactalbumin; Leucine; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Valine | 1996 |
'Fusel' alcohols induce hyphal-like extensions and pseudohyphal formation in yeasts.
Topics: 1-Propanol; Alcohols; Butanols; Cell Division; DNA Replication; DNA-Binding Proteins; Ethanol; Fungal Proteins; Hexanols; Isoleucine; Leucine; Methanol; Nitrogen; Pentanols; Phenylethyl Alcohol; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Valine; Yeasts | 1996 |
[Activity of threonine deaminase and biosynthesis of avermectins in the culture of Streptomyces avermitilis].
Topics: Ammonium Chloride; Drug Resistance, Microbial; Isoleucine; Ivermectin; Mutation; Streptomyces; Threonine; Threonine Dehydratase; Valine | 1995 |
Characterization of purified human recombinant cytochrome P4501A1-Ile462 and -Val462: assessment of a role for the rare allele in carcinogenesis.
Topics: Alleles; Base Sequence; Cytochrome P-450 Enzyme System; DNA, Complementary; Escherichia coli; Humans; Isoenzymes; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasms; Plasmids; Recombinant Proteins; Valine; Warfarin | 1996 |
End-product control of enzymes of branched-chain amino acid biosynthesis in Streptomyces coelicolor.
Topics: 2-Isopropylmalate Synthase; Acetolactate Synthase; Amino Acids; Amino Acids, Branched-Chain; Culture Media; Feedback; Isoleucine; Kinetics; Leucine; Models, Biological; Streptomyces; Valine | 1996 |
Immediately elevated postoperative serum branched-chain amino acids following effective GI decompression and enteral feeding.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Branched-Chain; Cholecystectomy; Decompression, Surgical; Digestive System Surgical Procedures; Enteral Nutrition; Female; Humans; Isoleucine; Kinetics; Leucine; Male; Middle Aged; Postoperative Period; Valine | 1996 |
Spectrophometric assay for measuring branched-chain amino acid concentrations: application for measuring the sensitivity of protein metabolism to insulin.
Topics: Amino Acid Oxidoreductases; Amino Acids, Branched-Chain; Blood Proteins; Chromatography, High Pressure Liquid; Enzyme Stability; Humans; Hyperinsulinism; Insulin; Isoleucine; Kinetics; Leucine; Leucine Dehydrogenase; NAD; Spectrophotometry; Valine | 1996 |
Production of heteropolymeric polyhydroxyalkanoate in Escherichia coli from a single carbon source.
Topics: Acyl Coenzyme A; Alcaligenes; Butyrates; Carbon; Cell Division; Culture Media; Escherichia coli; Glucose; Hydroxybutyrates; Isoleucine; Pentanoic Acids; Plasmids; Polyesters; Pyruvate Dehydrogenase Complex; Substrate Specificity; Threonine; Threonine Dehydratase; Transformation, Bacterial; Valine | 1996 |
Selective identification of threonine, valine, and isoleucine sequential connectivities with a TVI-CBCACONH experiment.
Topics: Amino Acid Sequence; Humans; Image Processing, Computer-Assisted; Isoleucine; Magnetic Resonance Spectroscopy; Threonine; Valine | 1996 |
Leucine metabolism in rats with cirrhosis.
Topics: Animals; Carbon Tetrachloride Poisoning; Evaluation Studies as Topic; In Vitro Techniques; Isoleucine; Keto Acids; Leucine; Liver; Liver Cirrhosis, Experimental; Male; Oxidation-Reduction; Perfusion; Protein Biosynthesis; Rats; Rats, Wistar; Valine | 1996 |
Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks.
Topics: Acidosis; Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Chickens; Glutamate Dehydrogenase; Glutamine; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Valine | 1996 |
Effects of amitriptyline on rat plasma and brain content of monoamine precursors and other large neutral amino acids.
Topics: Adrenergic Uptake Inhibitors; Amino Acids; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Brain; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Sprague-Dawley; Valine | 1995 |
Synergy in protein engineering. Mutagenic manipulation of protein structure to simplify semisynthesis.
Topics: Chemical Phenomena; Chemistry, Physical; Isoleucine; Leucine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Engineering; Valine | 1996 |
Functional analysis of YCL09C: evidence for a role as the regulatory subunit of acetolactate synthase.
Topics: Acetoin; Acetolactate Synthase; Amino Acid Sequence; DNA; Electronic Data Processing; Enterobacteriaceae; Escherichia coli; Gene Expression Regulation, Fungal; Isoleucine; Molecular Sequence Data; Open Reading Frames; Polymerase Chain Reaction; Saccharomyces cerevisiae; Sequence Deletion; Sequence Homology, Amino Acid; Valine | 1996 |
Growth rate-related regulation of the ilvGMEDA operon of Escherichia coli K-12 is a consequence of the polar frameshift mutation in the ilvG gene of this strain.
Topics: Escherichia coli; Frameshift Mutation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Isoleucine; Leucine; Operon; Threonine Dehydratase; Transcription, Genetic; Valine | 1997 |
Conversion of prostaglandin G/H synthase-1 into an enzyme sensitive to PGHS-2-selective inhibitors by a double His513 --> Arg and Ile523 --> val mutation.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Histidine; Humans; Isoenzymes; Isoleucine; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Sulfonamides; Thiophenes; Valine | 1997 |
Import of branched-chain amino acids in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Amino Acids; Gene Expression Regulation, Fungal; Glutamine; Isoleucine; Leucine; Membrane Transport Proteins; Proline; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transformation, Genetic; Valine | 1996 |
Sequence requirements of the HIV-1 protease flap region determined by saturation mutagenesis and kinetic analysis of flap mutants.
Topics: Amino Acid Sequence; Binding Sites; Glycine; HIV Protease; HIV-1; Isoleucine; Kinetics; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Recombinant Proteins; Solvents; Valine | 1997 |
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Topics: Administration, Oral; Adult; Aged; Alanine; Amino Acids; Asparagine; C-Peptide; Codon; DNA-Binding Proteins; Female; Glucose; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Serine; Transcription Factors; Valine | 1997 |
Decreased plasma and tissue isoleucine levels after simulated gastrointestinal bleeding by blood gavages in chronic portacaval shunted rats.
Topics: Ammonia; Animals; Cattle; Cerebral Cortex; Erythrocytes; Gastrointestinal Hemorrhage; Isoleucine; Leucine; Liver; Male; Muscle, Skeletal; Portacaval Shunt, Surgical; Rats; Rats, Wistar; Urea; Valine | 1997 |
The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.
Topics: Arginine; Catalysis; Citrobacter freundii; Crystallization; Crystallography, X-Ray; Isoleucine; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Phenylpropionates; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Tyrosine Phenol-Lyase; Valine | 1997 |
The effects of anaplerotic substrates on D-3-hydroxybutyrate metabolism in the heart.
Topics: Animals; Heart; Hydroxybutyrates; Isoleucine; Male; Methionine; Myocardium; Propionates; Rats; Rats, Wistar; Valine | 1997 |
Decreased agonist sensitivity of human GABA(A) receptors by an amino acid variant, isoleucine to valine, in the alpha1 subunit.
Topics: Baculoviridae; Cell Line; DNA Primers; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Humans; Isoleucine; Patch-Clamp Techniques; Point Mutation; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Valine | 1997 |
Effect of ruminally degraded protein on protein available at the intestine assessed using blood amino acid concentrations.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Caseins; Cattle; Diet; Dietary Proteins; Digestion; Eating; Female; Fermentation; Glycine max; Intestinal Absorption; Intestine, Small; Isoleucine; Lactation; Leucine; Medicago sativa; Milk; Nitrogen; Random Allocation; Rumen; Valine; Zea mays | 1997 |
The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins.
Topics: Animals; Hepacivirus; Humans; Isoleucine; Mice; Mutagenesis; Valine; Viral Nonstructural Proteins | 1997 |
Increasing valine, isoleucine, and total branched-chain amino acids for lactating sows.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Animals, Suckling; Body Weight; Diet; Dose-Response Relationship, Drug; Eating; Female; Isoleucine; Lactation; Milk; Random Allocation; Swine; Urea; Valine | 1997 |
A proposed mutation, Val781Ile, associated with hyperkalemic periodic paralysis and cardiac dysrhythmia is a benign polymorphism.
Topics: Adult; Arrhythmias, Cardiac; Cell Line; Child; Humans; Hyperkalemia; Isoleucine; Male; Muscle, Skeletal; Paralyses, Familial Periodic; Point Mutation; Polymorphism, Genetic; Protein Structure, Secondary; Recombinant Proteins; Sodium Channels; Transfection; Valine | 1997 |
Probing novel elements for protein splicing in the yeast Vma1 protozyme: a study of replacement mutagenesis and intragenic suppression.
Topics: Amino Acid Sequence; Endodeoxyribonucleases; Isoleucine; Mutagenesis; Protein Splicing; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Suppression, Genetic; Tyrosine; Valine | 1997 |
Genotyping of the CYP1A1 and GSTM1 genes in esophageal carcinoma patients with special reference to smoking.
Topics: Adult; Aged; Aged, 80 and over; Benzo(a)pyrene; Biotransformation; Case-Control Studies; Chi-Square Distribution; Cytochrome P-450 Enzyme System; Esophageal Neoplasms; Female; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Isoleucine; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Smoking; Valine | 1997 |
A type 2b von Willebrand disease mutation (Ile546-->Val) associated with an unusual phenotype.
Topics: Adult; Anti-Bacterial Agents; Child; Female; Humans; Isoleucine; Male; Middle Aged; Phenotype; Platelet Aggregation; Point Mutation; Restriction Mapping; Ristocetin; Sequence Analysis, DNA; Valine; von Willebrand Diseases; von Willebrand Factor | 1997 |
Dual role of alpha-acetolactate decarboxylase in Lactococcus lactis subsp. lactis.
Topics: Acetoin; Acetolactate Synthase; Amino Acid Sequence; Amino Acids, Branched-Chain; Bacterial Proteins; Base Sequence; Carboxy-Lyases; Genes, Bacterial; Isoleucine; Lactates; Lactococcus lactis; Leucine; Molecular Sequence Data; Promoter Regions, Genetic; Pyruvic Acid; Transcription, Genetic; Valine | 1997 |
Correction of acidosis in dialysis patients increases branched-chain and total essential amino acid levels in muscle.
Topics: Acidosis; Adult; Aged; Aged, 80 and over; Amino Acids, Branched-Chain; Amino Acids, Essential; Bicarbonates; Dialysis; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Muscle, Skeletal; Valine | 1997 |
Empirical free energy calculations of human immunodeficiency virus type 1 protease crystallographic complexes. II. Knowledge-based ligand-protein interaction potentials applied to thermodynamic analysis of hydrophobic mutations.
Topics: Amino Acid Substitution; Binding Sites; Calorimetry; Computer Simulation; Crystallography, X-Ray; Entropy; HIV Protease; HIV Protease Inhibitors; Humans; Isoleucine; Ligands; Models, Chemical; Models, Molecular; Oligopeptides; Pepstatins; Point Mutation; Protein Conformation; Thermodynamics; Valine | 1996 |
POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.
Topics: Binding Sites; Cell Line; DNA; DNA-Binding Proteins; Humans; Isoleucine; Molecular Weight; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; Transcription Factor Brn-3; Transcription Factor Brn-3A; Transcription Factor Brn-3B; Transcription Factors; Transcriptional Activation; Valine | 1998 |
A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus.
Topics: Age of Onset; Animals; Apolipoprotein C-III; Apolipoproteins C; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; COS Cells; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Hepatocyte Nuclear Factor 4; Humans; Insulin; Insulin Secretion; Isoleucine; Male; Middle Aged; Nuclear Proteins; Pedigree; Phosphoproteins; Point Mutation; Thymidine Kinase; Tissue Distribution; Transcription Factors; Transcriptional Activation; Valine | 1998 |
Constricted flux through the branched-chain amino acid biosynthetic enzyme acetolactate synthase triggers elevated expression of genes regulated by rpoS and internal acidification.
Topics: Acetolactate Synthase; Amino Acids, Branched-Chain; Bacterial Proteins; Enzyme Inhibitors; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Reporter; Isoleucine; Luminescent Measurements; Promoter Regions, Genetic; Salicylates; Sigma Factor; Sulfonylurea Compounds; Valine | 1998 |
Quick responses of plasma amino acid concentration to changes in dietary amino acid levels in rats.
Topics: Amino Acids, Essential; Animals; Arginine; Body Weight; Diet; Eating; Glycine; Isoleucine; Lysine; Male; Rats; Rats, Wistar; Threonine; Tyrosine; Valine | 1998 |
Mechanisms contributing to muscle-wasting in acute uremia: activation of amino acid catabolism.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acidosis; Acute Disease; Administration, Oral; Amino Acids; Animals; Carbonates; Enzyme Activation; Isoenzymes; Isoleucine; Ketone Oxidoreductases; Male; Mitochondria; Multienzyme Complexes; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transfer RNA Aminoacylation; Uremia; Valine; Wasting Syndrome | 1998 |
Enzyme structure with two catalytic sites for double-sieve selection of substrate.
Topics: Adenosine Monophosphate; Binding Sites; Crystallography, X-Ray; Escherichia coli; Hydrogen Bonding; Hydrolysis; Isoleucine; Isoleucine-tRNA Ligase; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Conformation; Protein Folding; Protein Structure, Secondary; RNA, Transfer, Ile; Substrate Specificity; Thermus thermophilus; Transfer RNA Aminoacylation; Valine | 1998 |
Computational analysis of thermal stability: effect of Ile-->Val mutations in human lysozyme.
Topics: Algorithms; Computer Simulation; Enzyme Stability; Hot Temperature; Humans; Isoleucine; Models, Chemical; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Protein Denaturation; Thermodynamics; Valine | 1998 |
Computer modelling of dynamics of Ser92X deoxymyoglobin mutants.
Topics: Alanine; Animals; Computer Simulation; Crystallography, X-Ray; Humans; Isoleucine; Models, Molecular; Myoglobin; Point Mutation; Protein Conformation; Serine; Threonine; Valine; Whales | 1998 |
Position dependence of non-polar amino acid intrinsic helical propensities.
Topics: Algorithms; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Circular Dichroism; Databases, Factual; Energy Transfer; Glycine; Isoleucine; Leucine; Methionine; Models, Molecular; Molecular Sequence Data; Peptides; Protein Structure, Secondary; Templates, Genetic; Valine | 1998 |
High-fidelity translation of recombinant human hemoglobin in Escherichia coli.
Topics: Escherichia coli; Hemoglobins; Humans; Isoleucine; Protein Biosynthesis; Recombinant Proteins; Valine | 1998 |
Sieves in sequence.
Topics: Adenosine Triphosphate; Binding Sites; Escherichia coli; Hydrolysis; Isoleucine; Isoleucine-tRNA Ligase; Substrate Specificity; Thermus thermophilus; Transfer RNA Aminoacylation; Valine | 1998 |
Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination.
Topics: Animals; Binding Sites; Cadmium; Calbindins; Calcium; Calmodulin; Carboxylic Acids; Drosophila melanogaster; Isoleucine; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; S100 Calcium Binding Protein G; S100 Proteins; Titrimetry; Troponin C; Valine | 1998 |
Properties of mutant SHV-5 beta-lactamases constructed by substitution of isoleucine or valine for methionine at position 69.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Escherichia coli; Genes, Bacterial; Isoleucine; Methionine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Valine | 1998 |
Association of Ile462Val (Exon 7) polymorphism of cytochrome P450 IA1 with lung cancer in the Asian population: further evidence from a case-control study in Okinawa.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asian People; Australia; Case-Control Studies; China; Cytochrome P-450 CYP1A1; Exons; Humans; Isoleucine; Japan; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Valine; White People | 1998 |
Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma.
Topics: Amino Acid Substitution; Animals; Asthma; Humans; Hypersensitivity; Immunoglobulin E; Isoleucine; Mice; Mice, Inbred BALB C; Receptors, Interleukin-4; Up-Regulation; Valine | 1998 |
Structural role of the 30's loop in determining the ligand specificity of the human immunodeficiency virus protease.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid Endopeptidases; Binding Sites; Crystallography, X-Ray; HIV Protease; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Imidazoles; Isoleucine; Ligands; Macaca; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Recombinant Fusion Proteins; Valine | 1998 |
Functional role of position 22 in the homeodomain of Brn-3 transcription factors.
Topics: Animals; Chloramphenicol O-Acetyltransferase; Cricetinae; DNA-Binding Proteins; Fibroblasts; Herpes Simplex Virus Protein Vmw65; Homeodomain Proteins; Humans; Isoleucine; Mutagenesis, Site-Directed; Neurons; Plasmids; Transcription Factor Brn-3; Transcription Factor Brn-3A; Transcription Factor Brn-3B; Transcription Factors; Transcription, Genetic; Transfection; Valine | 1998 |
Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4.
Topics: Cell Line, Transformed; HIV-1; Humans; Isoleucine; Polymorphism, Genetic; Receptors, CCR2; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Cytokine; Receptors, HIV; Valine | 1998 |
Amino acid substitutions in the C-terminal regulatory domain disrupt allosteric effector binding to biosynthetic threonine deaminase from Escherichia coli.
Topics: Allosteric Regulation; Aminobutyrates; Calorimetry; Catalysis; Escherichia coli; Feedback; Isoleucine; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Spectrometry, Fluorescence; Threonine Dehydratase; Valine | 1998 |
Apoptosis of leukemia cells induced by valine-deficient medium.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Culture Media; DNA Fragmentation; Isoleucine; Kinetics; Leukemia L1210; Leukemia L5178; Mice; Tumor Cells, Cultured; Valine | 1998 |
Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.
Topics: Alleles; alpha-Macroglobulins; Alzheimer Disease; Amyloid beta-Peptides; DNA; Female; Gene Frequency; Genotype; Humans; Isoleucine; Logistic Models; Male; Multivariate Analysis; Neurofibrillary Tangles; Odds Ratio; Polymorphism, Genetic; Valine | 1998 |
Role of CCR2 genotype in the clinical course of syncytium-inducing (SI) or non-SI human immunodeficiency virus type 1 infection and in the time to conversion to SI virus variants.
Topics: Cells, Cultured; Confidence Intervals; Disease Progression; Genetic Variation; Genotype; Giant Cells; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Isoleucine; Leukocytes, Mononuclear; Male; Point Mutation; Proportional Hazards Models; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Time Factors; Valine | 1998 |
Polymorphisms of the beta chain of the high-affinity immunoglobulin E receptor (Fcepsilon RI-beta) in South African black and white asthmatic and nonasthmatic individuals.
Topics: Adolescent; Adult; Asthma; Black People; Chi-Square Distribution; Child; Exons; Female; Gene Frequency; Glutamic Acid; Glycine; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isoleucine; Leucine; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Receptors, IgE; South Africa; Valine; White People | 1998 |
Determinants of strand register in antiparallel beta-sheets of proteins.
Topics: Binding Sites; Computer Simulation; Cysteine; Disulfides; Hydrogen Bonding; Isoleucine; Models, Molecular; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Serine; Threonine; Valine | 1998 |
Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adipose Tissue; Animals; Body Weight; Diabetes Mellitus, Experimental; Female; Hydrolysis; Hyperglycemia; Insulin; Isoleucine; Kidney; Leucine; Liver; Liver Glycogen; Methylhistidines; Muscle Development; Muscle Proteins; Muscle, Skeletal; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Ubiquitins; Valine | 1998 |
Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans.
Topics: Alanine; Amino Acid Substitution; Chromatography, Gel; Circular Dichroism; Dimyristoylphosphatidylcholine; Electric Conductivity; Gramicidin; Ion Channels; Isoleucine; Leucine; Lipid Bilayers; Membrane Potentials; Models, Molecular; Structure-Activity Relationship; Valine | 1999 |
Conserved residues amino-terminal of cytoplasmic tyrosines contribute to the SHP-1-mediated inhibitory function of killer cell Ig-like receptors.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Cytoplasm; Humans; Intracellular Signaling Peptides and Proteins; Isoleucine; Killer Cells, Natural; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Immunologic; Receptors, KIR; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tyrosine; Valine | 1999 |
Polychlorinated biphenyls, cytochrome P4501A1 polymorphism, and postmenopausal breast cancer risk.
Topics: Aged; Alleles; Body Burden; Body Mass Index; Breast Neoplasms; Case-Control Studies; Chromatography, Gas; Confidence Intervals; Cytochrome P-450 CYP1A1; Environmental Pollutants; Exons; Female; Genotype; Homozygote; Humans; Isoleucine; Lipids; Logistic Models; Lung Neoplasms; New York; Odds Ratio; Polychlorinated Biphenyls; Polycyclic Aromatic Hydrocarbons; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Postmenopause; Risk Factors; Steroids; Valine | 1999 |
Identification and functional analysis of novel human melanocortin-4 receptor variants.
Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Body Mass Index; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Isoleucine; Male; Methionine; Mice; Middle Aged; Obesity; Pedigree; Polymorphism, Single-Stranded Conformational; Receptor, Melanocortin, Type 4; Receptors, Peptide; Recombinant Proteins; Threonine; Valine | 1999 |
Role of bkdR, a transcriptional activator of the sigL-dependent isoleucine and valine degradation pathway in Bacillus subtilis.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Isoleucine; Leucine-Responsive Regulatory Protein; Molecular Sequence Data; Nitrogen; Operon; Phenotype; Promoter Regions, Genetic; Sigma Factor; Trans-Activators; Transcription Factors; Valine | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
A novel missense mutation Ile538Val in the fibroblast growth factor receptor 3 in hypochondroplasia. Mutations in brief no. 122. Online.
Topics: Achondroplasia; Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Humans; Isoleucine; Molecular Sequence Data; Mutation, Missense; Phenotype; Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Valine | 1998 |
Cloning of branched chain amino acid biosynthesis genes and assays of alpha-acetolactate synthase activities in Leuconostoc mesenteroides subsp. cremoris.
Topics: Acetolactate Synthase; Amino Acid Sequence; Amino Acids, Branched-Chain; Base Sequence; Cloning, Molecular; Genes, Bacterial; Isoleucine; Leucine; Leuconostoc; Molecular Sequence Data; Operon; Physical Chromosome Mapping; Restriction Mapping; Sequence Analysis, DNA; Valine | 1999 |
Molecular characterization of the receptor-ligand complex for parathyroid hormone.
Topics: Amino Acid Sequence; Binding Sites; Humans; Isoleucine; Ligands; Macromolecular Substances; Methionine; Models, Molecular; Molecular Sequence Data; Parathyroid Hormone; Peptide Fragments; Protein Structure, Secondary; Receptors, Parathyroid Hormone; Serine; Valine | 1999 |
A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins.
Topics: Carbon Isotopes; Deuterium; Indicators and Reagents; Isoleucine; Isotope Labeling; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Valine | 1999 |
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Topics: Aminobutyrates; Asparagine; Binding Sites; Computer Simulation; Crystallography, X-Ray; HIV Protease Inhibitors; HIV-1; Isoleucine; Leucine; Lysine; Models, Molecular; Molecular Mimicry; Oligopeptides; Peptides, Cyclic; Phenylalanine; Protein Conformation; Stereoisomerism; Valine | 1999 |
Chemokine control of HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemokine CCL2; Chemokine CXCL12; Chemokines, CXC; Dimerization; Disease Progression; HIV Infections; HIV-1; Humans; Isoleucine; Point Mutation; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Cytokine; Valine | 1999 |
Cytochrome P4501A1 polymorphism as a susceptibility factor for breast cancer in postmenopausal Chinese women in Taiwan.
Topics: Amino Acid Substitution; Asian People; Body Mass Index; Breast Neoplasms; China; Contraceptives, Oral; Cytochrome P-450 CYP1A1; Estrogen Replacement Therapy; Exons; Female; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Variation; Humans; Incidence; Isoleucine; Menarche; Middle Aged; Parity; Polymorphism, Genetic; Pregnancy; Risk Factors; Smoking; Taiwan; Valine | 1999 |
The effect of branched chain amino acids on protein synthesis in two skeletal muscles of Japanese quail.
Topics: Amino Acids, Branched-Chain; Animals; Coturnix; Isoleucine; Kinetics; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Valine | 1999 |
Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease.
Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Child; Child, Preschool; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Metabolic Clearance Rate; Middle Aged; Valine | 1999 |
A novel missense mutation Ile193Val in cholesteryl ester transfer protein gene.
Topics: Base Sequence; Carrier Proteins; Cholesterol Ester Transfer Proteins; Chromosomes, Human, Pair 16; Glycoproteins; Humans; Isoleucine; Mutation, Missense; Polymerase Chain Reaction; Valine | 1999 |
Identification of amino acids responsible for the oxygen sensitivity of ferredoxins from Anabaena variabilis using site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Anabaena; Escherichia coli; Ferredoxins; Isoleucine; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogenase; Oxygen; Sequence Alignment; Valine | 1999 |
Characterization of the hinges of the effector loop in the reaction pathway of the activation of ras-proteins. Kinetics of binding of beryllium trifluoride to V29G and I36G mutants of Ha-ras-p21.
Topics: Beryllium; Fluorides; Glycine; Guanosine Diphosphate; Humans; Isoleucine; Kinetics; Point Mutation; Protein Binding; Protein Conformation; Proto-Oncogene Proteins p21(ras); Thermodynamics; Valine | 1999 |
Polymorphic forms of the protein L-isoaspartate (D-aspartate) O-methyltransferase involved in the repair of age-damaged proteins.
Topics: Aging; Amino Acid Sequence; Asian People; Base Sequence; Black People; Consensus Sequence; Female; Genetic Variation; Humans; Isoenzymes; Isoleucine; Jews; Kinetics; Korea; Los Angeles; Male; Molecular Sequence Data; Norway; Pedigree; Polymorphism, Genetic; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Substrate Specificity; Valine; White People | 1999 |
Necrotic tumor versus brain abscess: importance of amino acids detected at 1H MR spectroscopy--initial results.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Brain; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Female; Humans; Isoleucine; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Phantoms, Imaging; Sensitivity and Specificity; Valine | 1999 |
Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor beta subunit.
Topics: Amino Acid Substitution; Animals; Asparagine; Cell Differentiation; Cell Line; Cell Line, Transformed; Glutamic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Isoleucine; Macromolecular Substances; Mice; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Valine | 2000 |
[Telomerases: transformation trial!].
Topics: Alanine; Antineoplastic Agents; Aspartic Acid; Catalytic Domain; Cell Division; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Isoleucine; Neoplasms; RNA; Telomerase; Transformation, Genetic; Tumor Cells, Cultured; Valine | 1999 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil | 2000 |
Effects of a feedback-resistant aspartokinase III gene on L-isoleucine production in Escherichia coli K-12.
Topics: Aspartate Kinase; Escherichia coli; Feedback; Isoleucine; Kinetics; Plasmids; Recombination, Genetic; Valine | 1999 |
Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin. Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated
Topics: Amino Acid Sequence; Blotting, Southern; Catalysis; Cells, Cultured; Cloning, Molecular; Cytochrome P-450 Enzyme System; Glucosides; Isoleucine; Manihot; Models, Chemical; Molecular Sequence Data; Nitriles; Pichia; Plants, Genetically Modified; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Valine | 2000 |
Stability analysis for the cavity-filling mutations of the Myb DNA-binding domain utilizing free-energy calculations.
Topics: Amino Acid Substitution; Binding Sites; DNA; Isoleucine; Leucine; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Proto-Oncogene Proteins c-myb; Thermodynamics; Valine | 2000 |
Localized, stereochemically sensitive hydrophobic packing in an early folding intermediate of dihydrofolate reductase from Escherichia coli.
Topics: Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Escherichia coli; Isoleucine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Urea; Valine | 2000 |
Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.
Topics: Amino Acid Motifs; Amino Acid Substitution; Amino Acids, Branched-Chain; Bias; Binding Sites; Cell Membrane; Databases, Factual; Dimerization; Glycine; Glycophorins; Isoleucine; Mathematics; Membrane Proteins; Models, Molecular; Molecular Weight; Odds Ratio; Pliability; Protein Folding; Protein Structure, Secondary; Thermodynamics; Valine | 2000 |
Transthyretin Ile73Val is associated with familial amyloidotic polyneuropathy in a Bangladeshi family. Mutations in brief no. 158. Online.
Topics: Age of Onset; Amino Acid Substitution; Amyloid Neuropathies; Bangladesh; Humans; Isoleucine; Male; Middle Aged; Point Mutation; Prealbumin; Valine | 1998 |
Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.
Topics: Adult; Age Factors; Amino Acid Substitution; Body Mass Index; Breast Neoplasms; Case-Control Studies; Chi-Square Distribution; China; Confidence Intervals; Exercise; Female; Fibroadenoma; Gene Frequency; Genes, erbB-2; Genetic Carrier Screening; Genotype; Humans; Isoleucine; Menarche; Middle Aged; Odds Ratio; Polymorphism, Restriction Fragment Length; Proto-Oncogene Mas; Receptor, ErbB-2; Reference Values; Risk Factors; Valine | 2000 |
Effects of mutations on the thermodynamics of a protein folding reaction: implications for the mechanism of formation of the intermediate and transition states.
Topics: Animals; CD2 Antigens; Guanidine; Isoleucine; Kinetics; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Rats; Recombinant Fusion Proteins; Sulfates; Temperature; Thermodynamics; Valine | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
The effects of branched-chain amino acids on sow and litter performance.
Topics: Amino Acids, Branched-Chain; Animal Feed; Animals; Body Weight; Female; Isoleucine; Lactation; Leucine; Litter Size; Male; Milk; Swine; Valine; Weaning | 2000 |
Importance of valine at position 152 for the substrate transport and 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane binding of dopamine transporter.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Biological Transport; Carrier Proteins; Cattle; Cocaine; COS Cells; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Isoleucine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Valine | 2000 |
Identification of three novel mutations (E196K, V203I, E211Q) in the prion protein gene (PRNP) in inherited prion diseases with Creutzfeldt-Jakob disease phenotype.
Topics: Aged; Amino Acid Substitution; Amyloid; Creutzfeldt-Jakob Syndrome; Female; Glutamic Acid; Glutamine; Humans; Isoleucine; Lysine; Male; Middle Aged; Mutation, Missense; Phenotype; Prion Proteins; Prions; Protein Precursors; Valine | 2000 |
A Di-leucine signal in the ubiquitin moiety. Possible involvement in ubiquitination-mediated endocytosis.
Topics: Amino Acid Sequence; Animals; Antigens, Differentiation, B-Lymphocyte; Cytoplasm; Endocytosis; HeLa Cells; Histocompatibility Antigens Class II; Humans; Isoleucine; Leucine; Mice; Molecular Sequence Data; Receptors, Interleukin-2; Recombinant Fusion Proteins; Signal Transduction; Ubiquitins; Valine | 2000 |
Binding of O(2) and its reduction are both retarded by replacement of valine 279 by isoleucine in cytochrome c oxidase from Paracoccus denitrificans.
Topics: Amino Acid Substitution; Conserved Sequence; Cytochrome b Group; Cytochromes; Electron Transport Complex IV; Escherichia coli; Escherichia coli Proteins; Heme; Isoleucine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Paracoccus denitrificans; Photolysis; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Valine | 2000 |
Atopy and the human IL-4 receptor alpha chain.
Topics: Amino Acid Substitution; Asthma; Genetic Variation; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isoleucine; Leukocytes, Mononuclear; Promoter Regions, Genetic; Receptors, IgE; Receptors, Interleukin-4; Signal Transduction; STAT6 Transcription Factor; Trans-Activators; Valine | 2000 |
Valyl-tRNA synthetase from Escherichia coli MALDI-MS identification of the binding sites for L-valine or for noncognate amino acids upon qualitative comparative labeling with reactive amino-acid analogs.
Topics: Amino Acid Sequence; Binding Sites; Diethyl Pyrocarbonate; Escherichia coli; Ethylmaleimide; Isoleucine; Ketones; Kinetics; Molecular Sequence Data; Norleucine; Peptides; Phenylalanine; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thermus thermophilus; Time Factors; Valine; Valine-tRNA Ligase | 2000 |
Contribution of the 30/36 hydrophobic contact at the C-terminus of the alpha-helix to the stability of the ubiquitin molecule.
Topics: Calorimetry, Differential Scanning; Genetic Variation; Isoleucine; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Thermodynamics; Ubiquitins; Valine | 2000 |
Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metab
Topics: Alternative Splicing; Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Animals; Base Sequence; Child, Preschool; Consanguinity; COS Cells; DNA Mutational Analysis; Enzyme Stability; Exons; Female; Heterozygote; Humans; Introns; Isoleucine; Male; Mitochondria; Mutation; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pakistan; Protein Transport; Sequence Deletion; Transfection; Valine | 2000 |
Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.
Topics: Animals; Carrier Proteins; Electrophoresis, Polyacrylamide Gel; Eukaryotic Initiation Factor-4E; Food; Food Deprivation; Intracellular Signaling Peptides and Proteins; Isoleucine; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus; Valine | 2000 |
Allergy-associated polymorphisms of the Fc epsilon RI beta subunit do not impact its two amplification functions.
Topics: Basophils; Cell Line; Cell Membrane; Gene Amplification; Genetic Variation; Glutamic Acid; Glycine; Humans; Hypersensitivity, Immediate; Intracellular Fluid; Isoleucine; Leucine; Polymorphism, Genetic; Protein Processing, Post-Translational; Receptors, IgE; Transfection; U937 Cells; Valine | 2000 |
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
Topics: Adult; Aged; Amino Acid Substitution; Breast Neoplasms; Disease-Free Survival; Female; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Isoleucine; Middle Aged; Polymorphism, Genetic; Proportional Hazards Models; Receptors, Estrogen; Survival Analysis; Treatment Outcome; Valine | 2000 |
Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.
Topics: Alanine; Alkylating Agents; Alleles; Antineoplastic Agents, Alkylating; Catalysis; Chlorambucil; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glutathione Transferase; Humans; Isoleucine; Kinetics; Polymorphism, Genetic; Protein Isoforms; Thiotepa; Valine | 2000 |
Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Calorimetry, Differential Scanning; Crystallography, X-Ray; Enzyme Stability; Glycine; Humans; Isoleucine; Leucine; Membrane Proteins; Methionine; Muramidase; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Thermodynamics; Valine | 2000 |
Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease.
Topics: Animals; Brain; Glutamic Acid; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Neurons; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes; Valine | 2000 |
RNA helicase dynamics in pre-mRNA splicing.
Topics: Acid Anhydride Hydrolases; Adenosine Triphosphate; Amino Acid Sequence; Catalysis; Cell Division; DEAD-box RNA Helicases; Dose-Response Relationship, Drug; Fungal Proteins; Genes, Dominant; Hydrolysis; Isoleucine; Molecular Sequence Data; Mutation, Missense; Nucleoside-Triphosphatase; Phenotype; Plasmids; Protein Structure, Tertiary; Recombinant Proteins; RNA Helicases; RNA Splicing; RNA Splicing Factors; RNA, Double-Stranded; RNA, Messenger; Saccharomyces cerevisiae Proteins; Spliceosomes; Suppression, Genetic; Temperature; Valine; Yeasts | 2000 |
Molecular mechanism for functional interaction between DnaA protein and acidic phospholipids: identification of important amino acids.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Base Sequence; Cardiolipins; DNA-Binding Proteins; Dose-Response Relationship, Drug; Escherichia coli; Isoleucine; Lysine; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phospholipids; Plasmids; Protein Binding; Time Factors; Valine | 2001 |
Serotonergic markers and lowered plasma branched-chain-amino acid concentrations in fibromyalgia.
Topics: Adult; Amino Acids, Branched-Chain; Biomarkers; Case-Control Studies; Female; Fibromyalgia; Humans; Isoleucine; Leucine; Male; Middle Aged; Paroxetine; Phenylalanine; Selective Serotonin Reuptake Inhibitors; Tryptophan; Valine | 2000 |
Evidence for two distinct effector-binding sites in threonine deaminase by site-directed mutagenesis, kinetic, and binding experiments.
Topics: Arabidopsis; Binding Sites; Gene Expression Regulation, Enzymologic; Isoleucine; Kinetics; Models, Theoretical; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Threonine Dehydratase; Valine | 2000 |
Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase.
Topics: Adenosine; Binding Sites; Crystallography, X-Ray; Hydrolysis; Isoleucine; Models, Chemical; Models, Molecular; Proline; Protein Binding; Protein Structure, Tertiary; RNA, Transfer, Val; Thermus thermophilus; Threonine; Valine; Valine-tRNA Ligase | 2000 |
An in vivo study of ovine placental transport of essential amino acids.
Topics: Amino Acids; Animals; Female; Histidine; Isoleucine; Leucine; Lysine; Methionine; Oxygen Consumption; Phenylalanine; Placenta; Placental Circulation; Pregnancy; Sheep; Threonine; Tryptophan; Umbilical Arteries; Umbilical Veins; Valine | 2001 |
Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise.
Topics: Adult; Amino Acids, Branched-Chain; Analysis of Variance; Creatine Kinase; Diet; Dietary Supplements; Exercise Test; Exercise Tolerance; Follow-Up Studies; Humans; Isoleucine; L-Lactate Dehydrogenase; Leucine; Male; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Physical Exertion; Time Factors; Valine | 2000 |
Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase.
Topics: Acetic Acid; Acyl Coenzyme A; Acyl-CoA Dehydrogenases; Carbon Isotopes; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Isoleucine; Leucine; Monensin; Oxidoreductases; Streptomyces; Substrate Specificity; Valine | 2001 |
Fragmentary form of thermostable leucine dehydrogenase of Bacillus stearothermophilus: its construction and reconstitution of active fragmentary enzyme.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Geobacillus stearothermophilus; Hydrogen-Ion Concentration; Isoleucine; Leucine; Leucine Dehydrogenase; Molecular Sequence Data; Oxygen; Peptides; Plasmids; Protein Structure, Tertiary; Substrate Specificity; Temperature; Valine | 2001 |
Prevalence and conditions of selection of E44D/A and V118I human immunodeficiency virus type 1 reverse transcriptase mutations in clinical practice.
Topics: Alanine; Amino Acid Substitution; Anti-HIV Agents; Aspartic Acid; Drug Resistance, Microbial; Gene Frequency; Glutamic Acid; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Mutation; Valine | 2001 |
Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Heme; Humans; Isoleucine; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Phenylalanine; Protein Conformation; Recombinant Proteins; Thermodynamics; Valine | 2001 |
Direct comparison of experimental and calculated folding free energies for hydrophobic deletion mutants of chymotrypsin inhibitor 2: free energy perturbation calculations using transition and denatured states from molecular dynamics simulations of unfoldi
Topics: Alanine; Amino Acid Substitution; Chymotrypsin; Computer Simulation; Glycine; Hordeum; Isoleucine; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Denaturation; Protein Folding; Reproducibility of Results; Serine Proteinase Inhibitors; Thermodynamics; Valine | 2001 |
Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells.
Topics: Allosteric Regulation; Amino Acids, Cyclic; Cell Line; Decarboxylation; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; Islets of Langerhans; Isoleucine; Leucine; Mitochondria; Models, Biological; Oxidation-Reduction; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Biosynthesis; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Valine | 2001 |
Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Isoleucine; Isradipine; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Structure, Secondary; Protein Subunits; Recombinant Proteins; Valine; Xenopus laevis | 2001 |
Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Asparagine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colchicine; Drug Resistance, Multiple; Etoposide; Genetic Vectors; Glycine; Humans; Isoleucine; Mice; Mutagenesis, Site-Directed; Protein Conformation; Transduction, Genetic; Transfection; Valine; Vinblastine | 2001 |
Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11.
Topics: Alleles; Amino Acid Substitution; Exons; Haplotypes; Humans; Isoleucine; Molecular Sequence Data; Polymorphism, Single Nucleotide; Receptors, Interleukin-4; Valine | 2001 |
Oral administration of leucine stimulates ribosomal protein mRNA translation but not global rates of protein synthesis in the liver of rats.
Topics: Administration, Oral; Animals; Carrier Proteins; Intracellular Signaling Peptides and Proteins; Isoleucine; Leucine; Liver; Male; Phosphoproteins; Phosphorylation; Polyribosomes; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Reference Values; Ribosomal Protein S6 Kinases; Ribosomal Proteins; RNA, Messenger; Valine | 2001 |
Re: Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.
Topics: Alleles; Asian People; Black People; Breast Neoplasms; Case-Control Studies; Female; Humans; Isoleucine; Polymerase Chain Reaction; Polymorphism, Genetic; Population Surveillance; Receptor, ErbB-2; Risk; Valine; White People | 2001 |
Metabolism of branched-chain amino acids in starved rats: the role of hepatic tissue.
Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Aspartate Aminotransferases; Glucose; Isoleucine; Keto Acids; Leucine; Liver; Male; Muscle, Skeletal; Organ Size; Oxidation-Reduction; Potassium; Protein Biosynthesis; Proteins; Rats; Rats, Wistar; Sodium; Starvation; Valine | 2001 |
A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivation.
Topics: Amino Acid Sequence; Animals; Electrophysiology; Humans; Isoleucine; Kinetics; Models, Biological; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Mutation; Myocardium; Oocytes; Protein Isoforms; Protein Structure, Tertiary; Sodium Channels; Valine; Xenopus | 2001 |
The Val-210-Ile pathogenic Creutzfeldt-Jakob disease mutation increases both the helical and aggregation propensities of a sequence corresponding to helix-3 of PrP(C).
Topics: Amino Acid Sequence; Circular Dichroism; Creutzfeldt-Jakob Syndrome; Isoleucine; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; PrPC Proteins; Valine | 2001 |
Leucine and protein metabolism in rats with chronic renal insufficiency.
Topics: Acidosis; Animals; Body Weight; Cholesterol; Creatinine; Disease Models, Animal; Eating; Isoleucine; Kidney Failure, Chronic; Leucine; Male; Muscle, Skeletal; Nephrectomy; Proteins; Rats; Rats, Wistar; Urea; Uremia; Valine | 2001 |
Plasma amino acid analyses in two cases of maple syrup urine disease.
Topics: Amino Acids; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Valine | 1999 |
Identification of inactivation determinants in the domain IIS6 region of high voltage-activated calcium channels.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; Calcium Channels, L-Type; Cell Line; Glycine; Humans; Isoleucine; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Valine | 2001 |
A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity.
Topics: Adjuvants, Immunologic; Alanine; Animals; Cells, Cultured; Cholera Toxin; Crystallography, X-Ray; G(M1) Ganglioside; Isoleucine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Valine | 2001 |
Substituted hydrophobic and hydrophilic residues at methionine-68 influence the chaperone-like function of alphaB-crystallin.
Topics: Animals; Binding Sites; Blotting, Western; Circular Dichroism; Cloning, Molecular; Crystallins; Electrophoresis, Polyacrylamide Gel; Isoleucine; Methionine; Mutagenesis, Site-Directed; Mutation; Naphthalenesulfonates; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Threonine; Time Factors; Valine | 2001 |
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules.
Topics: Amino Acid Sequence; Animals; Arabidopsis Proteins; Cattle; Chickens; Computational Biology; Conserved Sequence; ErbB Receptors; Humans; Isoleucine; Leucine; Mice; Molecular Sequence Data; Phenylalanine; Protein Structure, Tertiary; Rabbits; Rats; Receptor, Insulin; Repetitive Sequences, Amino Acid; Sequence Alignment; Valine | 2001 |
Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.
Topics: Alkanes; Amino Acids; Butylamines; Catalysis; Hydroxylation; Isoleucine; Leucine; Molecular Structure; Organoplatinum Compounds; Pentanoic Acids; Proline; Stereoisomerism; Valine; Water | 2001 |
Effects of branched-chain amino acids on placental amino acid transfer and insulin and glucagon release in the ovine fetus.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arteries; Biological Transport; Blood Glucose; Female; Fetal Blood; Glucagon; Insulin; Isoleucine; Kinetics; Lactic Acid; Leucine; Maternal-Fetal Exchange; Oxygen Consumption; Placenta; Pregnancy; Sheep; Umbilical Veins; Uterus; Valine; Veins | 2001 |
Metabolic oscillations in an E. coli fermentation.
Topics: Adenosine Triphosphate; Algorithms; Amino Acids; Biological Clocks; Bioreactors; Biotechnology; Cell Count; Escherichia coli; Fermentation; Frameshift Mutation; Genes, Bacterial; Glucose; Guanosine Triphosphate; Isoleucine; Kinetics; Recombinant Proteins; Time Factors; Valine | 2001 |
Evolution of the biosynthesis of the branched-chain amino acids.
Topics: Acetolactate Synthase; Amino Acids; Bacteria; Citric Acid Cycle; Decarboxylation; Evolution, Chemical; Fatty Acids, Volatile; Isoleucine; Leucine; Valine | 1995 |
Effect of electroconvulsive therapy on biopterin and large neutral amino acids in severe, medication-resistant depression.
Topics: Adult; Aged; Amino Acids, Neutral; Biopterins; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Neopterin; Phenylalanine; Psychiatric Status Rating Scales; Psychotic Disorders; Reference Values; Treatment Outcome; Tryptophan; Tyrosine; Valine | 2001 |
Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen.
Topics: Adenylyl Cyclases; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Escherichia coli; Exotoxins; Gene Expression; Glutamic Acid; Glycine; Isoleucine; Lysine; Receptors, Peptide; Recombinant Fusion Proteins; Tyrosine; Valine | 2001 |
The roles of the N-terminal portions of various tachykinins in promoting salivation.
Topics: Analysis of Variance; Animals; Eledoisin; Injections, Intraperitoneal; Isoleucine; Kassinin; Male; Models, Animal; Neurokinin A; Neurokinin B; Phenylalanine; Rats; Rats, Sprague-Dawley; Salivation; Serine; Statistics as Topic; Submandibular Gland; Tachykinins; Tyrosine; Valine | 2001 |
The conserved sites for the FK506-binding proteins in ryanodine receptors and inositol 1,4,5-trisphosphate receptors are structurally and functionally different.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcium; Calcium Channels; COS Cells; Cyclic ADP-Ribose; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate Receptors; Isoleucine; Leucine; Magnesium; Microsomes; Molecular Sequence Data; Mutation; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sequence Homology, Amino Acid; Tacrolimus; Tacrolimus Binding Proteins; Transfection; Valine | 2001 |
[Maple syrup urine disease].
Topics: Atrophy; Brain; Cerebellum; Chromatography, Paper; Female; Humans; Infant; Isoleucine; Leucine; Magnetic Resonance Imaging; Maple Syrup Urine Disease; Mesencephalon; Valine | 2001 |
Energetics of side chain packing in staphylococcal nuclease assessed by exchange of valines, isoleucines, and leucines.
Topics: Amino Acid Substitution; Enzyme Stability; Guanidine; Isoleucine; Leucine; Methionine; Micrococcal Nuclease; Mutagenesis, Site-Directed; Protein Denaturation; Solvents; Spectrometry, Fluorescence; Thermodynamics; Valine | 2001 |
Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cytoplasm; DNA Mutational Analysis; Glutathione Transferase; Humans; Integrin beta1; Intracellular Signaling Peptides and Proteins; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Membrane Proteins; Mice; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Peptides; Polypyrimidine Tract-Binding Protein; Protein Binding; Protein Folding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Ribonucleoproteins; RNA-Binding Proteins; Sequence Homology, Amino Acid; Two-Hybrid System Techniques; Valine | 2002 |
N-terminal contributions of the gamma-subunit of fetal hemoglobin to its tetramer strength: remote effects at subunit contacts.
Topics: Amino Acid Sequence; Aspartic Acid; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Fetal Hemoglobin; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoleucine; Kinetics; Leucine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Valine | 2002 |
Flow cytometry as a useful tool for process development: rapid evaluation of expression systems.
Topics: Arabinose; Bioreactors; Escherichia coli; Flow Cytometry; Gene Expression Regulation, Bacterial; Genetic Vectors; Glycine; Green Fluorescent Proteins; Isoleucine; Luminescent Proteins; Proline; Repetitive Sequences, Amino Acid; Research Design; Scattering, Radiation; Valine | 2002 |
Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cell Movement; Cell Polarity; CHO Cells; Contractile Proteins; Cricetinae; Cytoplasm; Cytoskeleton; Fibronectins; Filamins; Focal Adhesions; Humans; Integrin beta Chains; Integrins; Isoleucine; Jurkat Cells; Microfilament Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins; Talin; Valine | 2001 |
Role of backbone solvation in determining thermodynamic beta propensities of the amino acids.
Topics: Amino Acid Sequence; Amino Acids; Drug Stability; Isoleucine; Peptides; Protein Folding; Protein Structure, Secondary; Solubility; Static Electricity; Thermodynamics; Valine | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Regulatory interactions in Arabidopsis thaliana acetohydroxyacid synthase.
Topics: Acetolactate Synthase; Allosteric Regulation; Amino Acid Sequence; Arabidopsis; Binding Sites; Isoleucine; Leucine; Models, Molecular; Molecular Sequence Data; Mutation; Repetitive Sequences, Amino Acid; Valine | 2002 |
Mutational separation of two pathways for editing by a class I tRNA synthetase.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Escherichia coli Proteins; Esterification; Hydrolysis; Isoleucine; Isoleucine-tRNA Ligase; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Biosynthesis; Protein Conformation; Recombinant Fusion Proteins; RNA, Transfer, Amino Acyl; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Valine | 2002 |
Expression of Escherichia coli glutaredoxin 2 is mainly regulated by ppGpp and sigmaS.
Topics: Bacterial Proteins; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glucose; Glutaredoxins; Guanosine Tetraphosphate; Hydrogen Peroxide; Isoleucine; Isopropyl Thiogalactoside; NF-kappa B; Osmotic Pressure; Oxidoreductases; Protein Biosynthesis; Sigma Factor; Transcription Factor RelA; Valine | 2002 |
Mutational analysis of the three conserved valine residues of insulin and a proposal of "isosteric residue".
Topics: Animals; Circular Dichroism; Conserved Sequence; DNA Mutational Analysis; Dose-Response Relationship, Drug; Escherichia coli; Humans; Insulin; Isoleucine; Mice; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Precursors; Saccharomyces cerevisiae; Spectrometry, Mass, Electrospray Ionization; Swine; Threonine; Valine | 2001 |
Engineered recombinant enteropeptidase catalytic subunit: effect of N-terminal modification.
Topics: Animals; Binding Sites; Blotting, Western; Catalytic Domain; Cattle; Chromatography; Dipeptides; Electrophoresis, Polyacrylamide Gel; Enteropeptidase; Genetic Vectors; Humans; Isoleucine; Kinetics; Mutagenesis; Mutation; Plasmids; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Time Factors; Valine | 2002 |
Identification of essential residues in the type II Hsp40 Sis1 that function in polypeptide binding.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Cattle; Dimerization; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Fungal Proteins; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Isoleucine; Kinetics; Lactalbumin; Leucine; Luciferases; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phenotype; Phenylalanine; Polymerase Chain Reaction; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Time Factors; Valine | 2002 |
Evaluation of circulating levels and renal clearance of natural amino acids in patients with Cushing's disease.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Cushing Syndrome; Cystine; Cystinuria; Fasting; Female; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Isoleucine; Kidney; Leucine; Male; Middle Aged; Valine | 2002 |
Ideal ratio (relative to lysine) of tryptophan, threonine, isoleucine, and valine for chicks during the second and third weeks posthatch.
Topics: Amino Acids, Essential; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Digestion; Dose-Response Relationship, Drug; Energy Intake; Isoleucine; Lysine; Male; Nutritional Requirements; Threonine; Tryptophan; Valine; Weight Gain; Zea mays | 2002 |
Diagnosis and treatment of maple syrup disease: a study of 36 patients.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adult; Alanine; Amino Acids, Branched-Chain; Clinical Protocols; Female; Follow-Up Studies; Furosemide; Humans; Hydrazines; Infant, Newborn; Isoleucine; Ketone Oxidoreductases; Leucine; Mannitol; Maple Syrup Urine Disease; Multienzyme Complexes; Mutation; Neonatal Screening; Osmolar Concentration; Polymerase Chain Reaction; Saline Solution, Hypertonic; Sodium; Treatment Outcome; Valine | 2002 |
Biosynthesis of the branched-chain amino acids in the cyanobacterium Synechocystis PCC6803: existence of compensatory pathways.
Topics: Amino Acids, Branched-Chain; Cyanobacteria; Escherichia coli; Genetic Complementation Test; Isoleucine; Leucine; Mutation; Phenotype; Valine | 2002 |
Genetic polymorphisms of cytochrome P450 1A1 and risk of gallbladder cancer.
Topics: Alleles; Case-Control Studies; Cytochrome P-450 CYP1A1; DNA Primers; DNA, Neoplasm; Female; Gallbladder Neoplasms; Genotype; Humans; Incidence; Isoleucine; Japan; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Valine | 2002 |
Export of L-isoleucine from Corynebacterium glutamicum: a two-gene-encoded member of a new translocator family.
Topics: Amino Acid Transport Systems; Base Sequence; Biological Transport; Chromosome Mapping; Corynebacterium; DNA Transposable Elements; Isoleucine; Leucine; Molecular Sequence Data; Phylogeny; Transcription, Genetic; Valine | 2002 |
Biosynthesis of strawberry aroma compounds through amino acid metabolism.
Topics: Acyltransferases; Amino Acids; Butyrates; Fruit; Isoleucine; Odorants; Plant Proteins; Rosaceae; Valine | 2002 |
CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm.
Topics: Adenocarcinoma, Mucinous; Adult; Alleles; Carcinoma; Case-Control Studies; Confidence Intervals; Cystadenocarcinoma; Cytochrome P-450 CYP1A1; Female; Genotype; Humans; Incidence; Isoleucine; Middle Aged; Odds Ratio; Ovarian Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Risk; Turkey; Valine | 2002 |
Evaluation of isoleucine, leucine, and valine as a second-limiting amino acid for milk production in dairy cows fed grass silage diet.
Topics: Abomasum; Amino Acids; Amino Acids, Branched-Chain; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cattle; Fats; Female; Fermentation; Isoleucine; Lactation; Leucine; Mammary Glands, Animal; Milk; Milk Proteins; Poaceae; Rumen; Silage; Valine | 2002 |
Attenuation of the editing activity of the Escherichia coli leucyl-tRNA synthetase allows incorporation of novel amino acids into proteins in vivo.
Topics: Acylation; Alkynes; Amino Acid Sequence; Amino Acids; Cloning, Molecular; Escherichia coli; Glycine; Isoleucine; Kinetics; Leucine-tRNA Ligase; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Tyrosine; Valine | 2002 |
Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.
Topics: Alanine Transaminase; Binding Sites; Crystallization; Crystallography, X-Ray; Cysteine; D-Alanine Transaminase; Escherichia coli Proteins; Humans; Isoenzymes; Isoleucine; Lysine; Mitochondria; Models, Molecular; Oxo-Acid-Lyases; Protein Conformation; Protein Structure, Secondary; Pyridoxamine; Schiff Bases; Substrate Specificity; Transaminases; Valine | 2002 |
Absolute asymmetric photoreactions of aliphatic amino acids by circularly polarized synchrotron radiation: critically pH-dependent photobehavior.
Topics: Alanine; Amino Acids; Circular Dichroism; Deamination; Glycine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Photolysis; Spectrophotometry, Ultraviolet; Stereoisomerism; Valine | 2002 |
Novel mutations and SNPs identified in CCR2 using a new comprehensive denaturing gradient gel electrophoresis assay.
Topics: Amino Acid Substitution; Cohort Studies; Electrophoresis, Polyacrylamide Gel; Female; Genetic Predisposition to Disease; Genetic Variation; HIV Infections; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Isoleucine; Male; Mutation; Nucleic Acid Denaturation; Polymorphism, Single Nucleotide; Receptors, CCR2; Receptors, Chemokine; Valine | 2002 |
Factor VII mutant V154G models a zymogen-like form of factor VIIa.
Topics: Alanine; Amino Acid Chloromethyl Ketones; Binding Sites; Enzyme Precursors; Factor VII; Factor VIIa; Humans; Isoleucine; Point Mutation; Protein Conformation; Serine Proteinase Inhibitors; Thromboplastin; Valine | 2003 |
Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Azides; Biotinylation; Calcium; Cell Line; Cell Membrane; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epitopes; Ions; Isoleucine; Kinetics; Ligands; Mice; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Signal Transduction; Time Factors; Transfection; Tyrosine; Valine; Xenopus laevis | 2002 |
Leucine stimulates the secretion of hepatocyte growth factor by hepatic stellate cells.
Topics: Animals; Culture Media; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hepatocyte Growth Factor; Isoleucine; Leucine; Liver; Models, Statistical; Rats; Time Factors; Valine | 2002 |
Population-based case-control study of HER2 genetic polymorphism and breast cancer risk.
Topics: Alleles; Asian People; Breast Neoplasms; Case-Control Studies; China; Female; Genes, erbB-2; Genotype; Hong Kong; Humans; Incidence; Isoleucine; Middle Aged; Molecular Epidemiology; Ovarian Neoplasms; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Assessment; Valine | 2002 |
Effect of a new injectable male contraceptive on the seminal plasma amino acids studied by proton NMR spectroscopy.
Topics: Adult; Alanine; Amino Acids; Arginine; Contraceptive Agents, Male; Dimethyl Sulfoxide; Glutamic Acid; Glutamine; Humans; Injections; Isoleucine; Leucine; Lysine; Magnetic Resonance Spectroscopy; Male; Maleates; Polyesters; Polystyrenes; Semen; Styrenes; Valine; Vas Deferens | 2002 |
Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles.
Topics: Amino Acids; Bacterial Outer Membrane Proteins; Cold Temperature; Escherichia coli Proteins; Hydrolases; Isoleucine; Isotopes; Leucine; Membranes, Artificial; Micelles; Nuclear Magnetic Resonance, Biomolecular; Phospholipid Ethers; Sensitivity and Specificity; Valine | 2002 |
Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis.
Topics: Binding Sites; Calcium; Cell Line; Child; Gene Expression; Humans; Immunoblotting; Infant; Isoleucine; Male; Models, Molecular; Mutagenesis; Mutation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Static Electricity; Structure-Activity Relationship; Thrombasthenia; Transfection; Valine | 2003 |
Val64Ile polymorphism in the C-C chemokine receptor 2 is associated with reduced coronary artery calcification.
Topics: Adult; Aged; Amino Acid Substitution; Calcinosis; Cardiomyopathies; Coronary Vessels; Female; Genotype; Humans; Isoleucine; Male; Middle Aged; Models, Statistical; Polymorphism, Genetic; Receptors, CCR2; Receptors, Chemokine; Sex Factors; Valine | 2002 |
Biochemical and mass spectrometric evidence for quaternary structure modifications of plant threonine deaminase induced by isoleucine.
Topics: Arabidopsis; Binding Sites; Chromatography, Gel; Dimerization; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Isoleucine; Mass Spectrometry; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Threonine Dehydratase; Valine | 2002 |
Temperature dependence of mutant mevalonate kinase activity as a pathogenic factor in hyper-IgD and periodic fever syndrome.
Topics: Alleles; Amino Acid Substitution; Body Temperature; Cells, Cultured; Familial Mediterranean Fever; Fibroblasts; Genes, Recessive; Humans; Hydroxymethylglutaryl CoA Reductases; Hypergammaglobulinemia; Immunoglobulin D; Isoleucine; Leukocytes, Mononuclear; Mevalonic Acid; Mutation; Phosphotransferases (Alcohol Group Acceptor); Skin; Valine | 2002 |
A heterodimerizing leucine zipper coiled coil system for examining the specificity of a position interactions: amino acids I, V, L, N, A, and K.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Chickens; Circular Dichroism; Dimerization; Isoleucine; Leucine; Leucine Zippers; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Transcription Factors; Ultracentrifugation; Valine | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
Re: Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.
Topics: Alleles; Asian People; Breast Neoplasms; Case-Control Studies; Female; Genes, erbB-2; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Japan; Odds Ratio; Polymorphism, Genetic; Population Surveillance; Receptor, ErbB-2; Risk Assessment; Risk Factors; Valine | 2002 |
A novel Val648Ile substitution in RET protooncogene observed in a Cys634Arg multiple endocrine neoplasia type 2A kindred presenting with an adrenocorticotropin-producing pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Amino Acid Substitution; Arginine; Child; Cysteine; Drosophila Proteins; Female; Humans; Isoleucine; Male; Multiple Endocrine Neoplasia Type 2a; Pedigree; Pheochromocytoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Valine | 2002 |
Long-term prognosis by lamivudine monotherapy for severe acute exacerbation in chronic hepatitis B infection: emergence of YMDD motif mutant and risk of breakthrough hepatitis -- an open-cohort study.
Topics: Adult; Amino Acid Motifs; Amino Acid Substitution; Cohort Studies; DNA-Directed DNA Polymerase; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Isoleucine; Lamivudine; Male; Middle Aged; Mutation; Prognosis; Retrospective Studies; Reverse Transcriptase Inhibitors; Risk; Severity of Illness Index; Valine | 2003 |
Conserved proline residue at position 189 in cone visual pigments as a determinant of molecular properties different from rhodopsins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Avian Proteins; Cell Line; Chickens; Conserved Sequence; Epitopes; Eye Proteins; Genetic Vectors; Glycine; Humans; Isoleucine; Leucine; Mice; Proline; Retinal Cone Photoreceptor Cells; Retinal Pigments; Rhodopsin; Serine; Spectrophotometry; Thermodynamics; Valine | 2002 |
Serine metabolism in human pregnancy.
Topics: Adult; Carbon Isotopes; Fasting; Female; Glutamine; Glycine; Humans; Isoleucine; Kinetics; Leucine; Nitrogen Isotopes; Oxidation-Reduction; Pregnancy; Serine; Urea; Valine | 2003 |
Crystals of trp repressor suitable for high-resolution neutron Laue diffraction studies.
Topics: Bacterial Proteins; Crystallization; Deuterium; Diffusion; DNA-Binding Proteins; Escherichia coli; Isoleucine; Neutron Diffraction; Repressor Proteins; Solvents; Valine | 2003 |
Stability of cyclic beta-hairpins: asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair.
Topics: Amino Acid Sequence; Cysteine; Disulfides; Hydrogen Bonding; Isoleucine; Models, Molecular; Molecular Sequence Data; Peptides; Protein Folding; Protein Structure, Secondary; Thermodynamics; Tryptophan; Valine | 2003 |
Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
Topics: Amino Acid Substitution; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Asparagine; Aspartic Acid; Aspartic Acid Endopeptidases; Carbamates; Cell Line; Cell-Free System; CHO Cells; Cricetinae; Culture Media; Dipeptides; Endopeptidases; Humans; Intracellular Fluid; Isoleucine; Membrane Proteins; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Presenilin-1; Presenilin-2; Serine Proteinase Inhibitors; Threonine; Transfection; Up-Regulation; Valine | 2003 |
Interactions of various supplies of isoleucine, valine, leucine and tryptophan on the performance of laying hens.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Chickens; Diet; Dietary Proteins; Drug Interactions; Eating; Eggs; Female; Isoleucine; Leucine; Oviposition; Tryptophan; Valine | 2003 |
A founder effect in the hyperimmunoglobulinemia D and periodic fever syndrome.
Topics: Alleles; Europe; Familial Mediterranean Fever; Female; Founder Effect; Humans; Hypergammaglobulinemia; Immunoglobulin D; Isoleucine; Linkage Disequilibrium; Male; Pedigree; Syndrome; Valine | 2003 |
Metabolic engineering of valine- and isoleucine-derived glucosinolates in Arabidopsis expressing CYP79D2 from Cassava.
Topics: Arabidopsis; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Glucosinolates; Immunity, Innate; Isoleucine; Manihot; Plant Leaves; Plants, Genetically Modified; Valine | 2003 |
Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system.
Topics: Albumins; Amino Acids, Branched-Chain; Animals; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Hepatocytes; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isoleucine; Leucine; Male; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinases; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Valine | 2003 |
Skeletal muscle metabolism in Duchenne muscular dystrophy (DMD): an in-vitro proton NMR spectroscopy study.
Topics: Adolescent; Adult; Carnitine; Child; Child, Preschool; Humans; Immunohistochemistry; In Vitro Techniques; Isoleucine; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Valine | 2003 |
Symbiotic characterization of isoleucine+valine and leucine auxotrophs of Sinorhizobium meliloti.
Topics: DNA Transposable Elements; Isoleucine; Leucine; Medicago sativa; Mutagenesis; Sinorhizobium meliloti; Symbiosis; Valine | 2002 |
ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.
Topics: Alanine; Apolipoprotein A-I; Asian People; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cysteine; Genotype; Glycine; Haplotypes; Humans; India; Isoleucine; Linkage Disequilibrium; Lipids; Malaysia; Male; Methionine; Polymorphism, Genetic; Sequence Analysis, DNA; Singapore; Threonine; Triglycerides; Valine; White People | 2003 |
Kinetic studies on the inhibition of creatine kinase activity by branched-chain alpha-amino acids in the brain cortex of rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cerebral Cortex; Creatine Kinase; Enzyme Activation; Isoleucine; Keto Acids; Kinetics; Leucine; Maple Syrup Urine Disease; Rats; Rats, Wistar; Reference Values; Valine | 2003 |
Creatine kinase activity from rat brain is inhibited by branched-chain amino acids in vitro.
Topics: Amino Acids, Branched-Chain; Animals; Brain; Creatine Kinase; Energy Metabolism; Isoleucine; Kinetics; Leucine; Maple Syrup Urine Disease; Rats; Valine | 2003 |
The total branched-chain amino acid requirement in young healthy adult men determined by indicator amino acid oxidation by use of L-[1-13C]phenylalanine.
Topics: Amino Acids, Branched-Chain; Body Composition; Carbon Isotopes; Energy Intake; Humans; Isoleucine; Isotope Labeling; Leucine; Male; Nitrogen; Nutritional Requirements; Phenylalanine; Tyrosine; Valine | 2003 |
Global expression profiling and physiological characterization of Corynebacterium glutamicum grown in the presence of L-valine.
Topics: Acetolactate Synthase; Biological Transport, Active; Biotechnology; Corynebacterium; Dipeptides; Gene Deletion; Gene Expression; Gene Expression Profiling; Genes, Bacterial; Isoleucine; Leucine; Oligonucleotide Array Sequence Analysis; RNA, Bacterial; RNA, Messenger; Valine | 2003 |
Requirement of tryptophan in relation to the supply of large neutral amino acids in laying hens.
Topics: Amino Acids, Neutral; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dose-Response Relationship, Drug; Female; Isoleucine; Leucine; Nutritional Requirements; Oviposition; Phenylalanine; Regression Analysis; Tryptophan; Tyrosine; Valine; Weight Gain | 2003 |
New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.
Topics: Aged; Alleles; Aryldialkylphosphatase; Case-Control Studies; Esterases; Finland; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Heterozygote; Humans; Incidence; Isoleucine; Male; Middle Aged; Mutation; Odds Ratio; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prospective Studies; Prostatic Neoplasms; Risk Assessment; Risk Factors; Sampling Studies; Valine | 2003 |
Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Endopeptidases; Humans; Isoleucine; Methionine; Peptide Fragments; Protease Inhibitors; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Serine; Substrate Specificity; Valine | 2003 |
Ternary systems of naproxen with hydroxypropyl-beta-cyclodextrin and aminoacids.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amino Acids; Anti-Inflammatory Agents; Arginine; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cyclodextrins; Hydrogen-Ion Concentration; Isoleucine; Lysine; Microscopy, Electron, Scanning; Naproxen; Solubility; Valine | 2003 |
Diagnosis of maple syrup urine disease by determination of L-valine, L-isoleucine, L-leucine and L-phenylalanine in neonatal blood spots by gas chromatography-mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Phenylalanine; Reproducibility of Results; Valine | 2003 |
A human serotonin transporter mutation causes constitutive activation of transport activity.
Topics: Amino Acid Substitution; Animals; Biological Transport; Biotinylation; Carrier Proteins; COS Cells; Humans; Immunohistochemistry; Isoleucine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Nitric Oxide Donors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection; Valine | 2003 |
Whole-body fluxes and partitioning of amino acids to the mammary gland of cows fed fresh pasture at two levels of intake during early lactation.
Topics: Amino Acids; Animal Feed; Animals; Cattle; Female; Isoleucine; Lactation; Leucine; Lysine; Mammary Glands, Animal; Nitrogen; Poaceae; Valine | 2003 |
Histidine at position 61 and its adjacent amino acid residues are critical for the ability of SLAM (CD150) to act as a cellular receptor for measles virus.
Topics: Animals; Antigens, CD; Cell Line; CHO Cells; Cricetinae; Glycoproteins; Histidine; Humans; Immunoglobulins; Isoleucine; Measles virus; Receptors, Cell Surface; Receptors, Virus; Signaling Lymphocytic Activation Molecule Family Member 1; Species Specificity; Valine; Virus Replication | 2003 |
Induction of oxidative stress in rat brain by the metabolites accumulating in maple syrup urine disease.
Topics: Amino Acids; Animals; Animals, Newborn; Antioxidants; Cerebral Cortex; Culture Techniques; Dose-Response Relationship, Drug; Free Radicals; Isoleucine; Leucine; Lipid Peroxidation; Male; Maple Syrup Urine Disease; Oxidative Stress; Rats; Rats, Wistar; Valine | 2003 |
Isoleucine and valine metabolism in Escherichia coli. V. alpha-Ketoisovaleric acid accumulation.
Topics: Escherichia coli; Hemiterpenes; Isoleucine; Keto Acids; Ketones; Leucine; Valine | 1953 |
Some inhibitory interrelationships among leucine, isoleucine and valine.
Topics: Isoleucine; Leucine; Leuconostoc; Valine | 1954 |
Isoleucine and valine metabolism in Escherichia coli. V. Antagonism between isoleucine and valine.
Topics: Escherichia coli; Isoleucine; Leucine; Valine | 1955 |
The biosynthesis of isoleucine and valine. II. Independence of the biosynthetic pathways in Neurospora.
Topics: Biosynthetic Pathways; Isoleucine; Leucine; Neurospora; Valine | 1955 |
The biosynthesis of isoleucine and valine. III. Tracer experiments with L-threonine.
Topics: Isoleucine; Leucine; Neurospora; Threonine; Valine | 1955 |
Amino acid composition and electrophoretic properties of hypertensin I.
Topics: Amino Acids; Angiotensin Amide; Angiotensins; Arginine; Aspartic Acid; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Proline; Serine; Tyrosine; Valine | 1955 |
Leucine, isoleucine and valine relationships in the rat.
Topics: Animals; Isoleucine; Leucine; Phenylalanine; Rats; Valine | 1956 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Lipoic acid as a growth stimulant for Streptococcus faecalis in the presence of limiting quantities of isoleucine and valine.
Topics: Anti-Bacterial Agents; Enterococcus faecalis; Isoleucine; Thioctic Acid; Valine; Vitamin A; Vitamin K; Vitamins | 1957 |
The biosynthesis of isoleucine and valine. IV. Accumulation of citramalic and alpha, beta-dimethylmalic acids by a neurospora mutant.
Topics: Isoleucine; Leucine; Liver; Malates; Neurospora; Valine | 1957 |
Some factors influencing valine and isoleucine transaminase activity in Neurospora crassa.
Topics: Isoleucine; Neurospora; Neurospora crassa; Transaminases; Valine | 1958 |
Isoleucine and valine metabolism in Escherichia coli. VII. A negative feedback mechanism controlling isoleucine biosynthesis.
Topics: Escherichia coli; Isoleucine; Leucine; Valine | 1958 |
The inhibition of Escherichia coli by 1-penicillamine and its reversal by isoleucine, valine or leucine.
Topics: Cysteine; Escherichia coli; Isoleucine; Leucine; Penicillamine; Valine | 1958 |
Studies on the metabolism of valine, proline, leucine and isoleucine by rumen microorganisms in vitro.
Topics: Animals; Biochemical Phenomena; Humans; In Vitro Techniques; Isoleucine; Leucine; Proline; Rumen; Stomach; Valine | 1958 |
Isoleucine and valine metabolism in Escherichia coli. VIII. The formation of acetolactate.
Topics: Acetates; Escherichia coli; Isoleucine; Lactates; Valine | 1958 |
Maple syrup urine disease; an inborn error of the metabolism of valine, leucine, and isoleucine associated with gross mental deficiency.
Topics: Biochemical Phenomena; Child; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Valine | 1959 |
The accumulation of acetylmethylcarbinol and acetylethylcarbinol by a mutant of Neurospora crassa and its significance in the biosynthesis of isoleucine and valine.
Topics: Acetoin; Alcohols; Isoleucine; Ketones; Leucine; Neurospora; Neurospora crassa; Pentanones; Valine | 1959 |
Biosynthesis of valine and isoleucine. IV. alpha-Hydroxy-beta-keto acid reductoisomerase of Salmonella.
Topics: Carboxylic Acids; Isoleucine; Isomerases; Keto Acids; Leucine; Salmonella; Valine | 1961 |
Dihydroxy acid dehydrase: an enzyme involved in the biosynthesis of isoleucine and valine.
Topics: Hydro-Lyases; Isoleucine; Leucine; Oxidoreductases; Valine | 1961 |
Isoleucine and valine metabolism in Escherichia coli. X. The enzymatic formation of acetohydroxybutyrate.
Topics: Butyrates; Enzymes; Escherichia coli; Hydroxybutyrates; Isoleucine; Leucine; Lipid Metabolism; Valine | 1961 |
Isoleucine and valine metabolism in Escherichia coli. IX. Utilization of acetolactate and acetohydroxybutyrate.
Topics: Escherichia coli; Hydroxybutyrates; Isoleucine; Lactates; Leucine; Valine | 1960 |
Biosynthesis of valine and isoleucine. 2. Formation of alpha-acetolactate and alpha-aceto-alpha-hydroxybutyrate in Neurospora crassa and Escherichia coli.
Topics: Escherichia coli; Hydroxybutyrates; Isoleucine; Lactates; Neurospora crassa; Valine | 1960 |
Biosynthesis of valine and isoleucine. V. Electrophoretic studies on the reductoisomerase and reductase of Salmonella.
Topics: Isoleucine; Isomerases; Oxidoreductases; Salmonella; Valine | 1961 |
Biological activities of some homologs of isoleucine and valine.
Topics: Isoleucine; Leucine; Valine | 1961 |
[Contributions to the biochemistry of the silkworm. XXI. Variations of concentration in the hemolymph of a series of free amino acids (arginine, lysine, leucine, isoleucine, valine, phenylalanine) in the course of development of Bombyx mori L].
Topics: Amino Acids; Animals; Antifibrinolytic Agents; Arginine; Biochemical Phenomena; Bombyx; Hemolymph; Insecta; Isoleucine; Leucine; Lysine; Phenylalanine; Valine | 1961 |
A microbiological method for assessing the nutritional value of proteins. 2. The measurement of 'available' methionine, leucine, isoleucine, arginine, histidine, tryptophan and valine.
Topics: Arginine; Biological Assay; Diet; Histidine; Humans; Isoleucine; Leucine; Methionine; Nutrition Assessment; Nutritive Value; Proteins; Streptococcus; Tryptophan; Valine | 1962 |
Growth of Listeria monocytogenes in defined media.
Topics: Alanine; Arginine; Asparagine; Culture Media; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Listeria monocytogenes; Methionine; Proteins; Valine | 1961 |
Genetic instability with episome-mediated transfer in Escherichia coli.
Topics: Anti-Bacterial Agents; Chloramphenicol; Drug Resistance, Microbial; Escherichia coli; Histidine; Isoleucine; Methionine; Mutation; Norway; Plasmids; Streptomycin; Tetracycline; Threonine; Valine | 1962 |
Radiation-induced carboxylation reactions of aliphatic amino acids and monocarboxylic acids.
Topics: Amino Acids; Fatty Acids; Humans; Isoleucine; Leucine; Radiation; Radiation Effects; Valine | 1963 |
Effect of acute amino acid deficiencies on carcass composition and pancreatic function in the force-fed rat. II. Deficiencies of valine, lysine, tryptophan, leucine and isoleucine.
Topics: Amylases; Animals; Isoleucine; Leucine; Lipase; Lysine; Pancreas; Peptide Hydrolases; Rats; Tryptophan; Valine | 1963 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
Effectiveness of urea and ammonium nitrogen for the synthesis of dispensable amino acids by the chick.
Topics: Amino Acids; Ammonium Compounds; Animals; Arginine; Chickens; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Quaternary Ammonium Compounds; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1962 |
Multivalent repression in the biosynthesis of threonine in Salmonella typhimurium and Escherichia coli.
Topics: Escherichia coli; Isoleucine; Lyases; Oxidoreductases; Phosphotransferases; Salmonella typhimurium; Threonine; Valine | 1963 |
Control of isoleucine, valine, and leucine biosynthesis. I. Multivalent repression.
Topics: Biochemical Phenomena; Escherichia coli; Isoleucine; Leucine; Salmonella typhimurium; Valine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Nitrogen balance studies with subjects fed the essential amino acids in plasma pattern proportions.
Topics: Amino Acids, Essential; Cystine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
Effect of leucine-isoleucine and valine antagonism and comparison with the effect of ethionine on rat liver regeneration.
Topics: Animals; Dietary Proteins; DNA; Ethionine; Isoleucine; Leucine; Liver; Liver Regeneration; Rats; RNA; Valine | 1963 |
Synthesis of valine and isoleucine in the presence of a particulate cell fraction of Neurospora.
Topics: Enzymes; Isoleucine; Leucine; Neurospora; Valine | 1963 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[The Maillard reaction. II. Study of the behavior of 6 pure amino acids].
Topics: Amino Acids; Food Preservation; Food-Processing Industry; Isoleucine; Lysine; Maillard Reaction; Methionine; Phenylalanine; Threonine; Valine | 1963 |
Effect of amino acid imbalance on nitrogen retention. II. Interrelationships between methionine, valine, isoleucine and threonine as supplements to corn protein for dogs.
Topics: Amino Acids; Animals; Dietary Proteins; Dogs; Isoleucine; Methionine; Nitrogen; Proteins; Threonine; Valine; Zea mays | 1963 |
THE DIAGNOSIS OF MAPLE SYRUP URINE DISEASE (BRANCHED- CHAIN KETOACIDURIA) BY THE IN VITRO STUDY OF THE PERIPHERAL LEUKOCYTE.
Topics: Chromatography; Humans; In Vitro Techniques; Isoleucine; Keto Acids; Ketosis; Leucine; Leukocytes; Maple Syrup Urine Disease; Metabolism; Research; Valine | 1963 |
GENE TRANSFER BY F' STRAINS OF ESCHERICHIA COLI K-12. II. INTERACTION BETWEEN F-MEROGENOTE AND CHROMOSOME DURING TRANSFER.
Topics: Chromosomes; Escherichia coli; Escherichia coli K12; Galactose; Histidine; Isoleucine; Lactose; Leucine; Maltose; Mannitol; Methionine; Proline; Research; Serine; Streptomycin; Thiamine; Threonine; Tryptophan; Valine; Xylose | 1963 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleucine; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Proteins; Research; Serine; Valine | 1963 |
THE SPORE SURFACE IN PITHOMYCES CHARTARUM.
Topics: Electrons; Isoleucine; Leucine; Lipids; Metabolism; Microscopy; Microscopy, Electron; Research; Spores; Streptomyces; Valine | 1963 |
DIETARY TREATMENT OF A CHILD WITH MAPLE SYRUP URINE DISEASE (BRANCHED-CHAIN KETOACIDURIA).
Topics: Child; Diet; Diet Therapy; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Valine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
ISOLATION OF "LIPOPEPTIDES" FROM HEN OVIDUCT.
Topics: Animals; Chickens; Chromatography; Fatty Acids; Fatty Acids, Essential; Female; Glutamates; Glycine; Humans; Hydroxylamines; Isoleucine; Leucine; Lipopeptides; Lipoproteins; Oviducts; Palmitic Acid; Peptides; Poultry; Research; Valine | 1963 |
BIOSYNTHESIS OF VALINE AND ISOLEUCINE IN PLANTS. I. FORMATION OF ALPHA-ACETOLACTATE IN PHASEOLUS RADIATUS.
Topics: Benzoates; Cysteine; Dimercaprol; Edetic Acid; Isoleucine; Lactates; Magnesium; Manganese; Phaseolus; Plants; Proteins; Pyruvates; Research; Thiamine Pyrophosphate; Valine | 1963 |
SEMIAUTOMATIC ANALYSIS OF GLUCOSAMINE AND GALACTOSAMINE IN PROTEIN HYDROLYSATES.
Topics: Alanine; Ammonia; Arginine; Chromatography; Galactosamine; Glucosamine; Glycine; Glycoproteins; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Protein Hydrolysates; Research; Tyrosine; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
RAPID DETERMINATION OF SOME PLASMA AMINOACIDS IN SUBCLINICAL KWASHIORKOR.
Topics: Amino Acids; Blood Chemical Analysis; Blood Proteins; Child; Chromatography; Diagnosis; Dietary Proteins; Glutamine; Glycine; Humans; Isoleucine; Kwashiorkor; Leucine; Methionine; Proteins; Taurine; Uganda; Valine | 1964 |
THE FREQUENCY OF ERRORS IN PROTEIN BIOSYNTHESIS.
Topics: Animals; Carbon Isotopes; Female; Humans; Isoleucine; Leucine; Ovalbumin; Oviducts; Peptides; Phenylalanine; Poultry; Protein Biosynthesis; Proteins; Research; RNA; Valine | 1963 |
PURIFICATION AND PROPERTIES OF VALINE-ACTIVATING ENZYME FROM WHEAT GERM.
Topics: Adenosine Triphosphate; Aminobutyrates; Benzoates; Carbon Isotopes; Chemical Phenomena; Chemistry; Diphosphates; Enzyme Activators; Glutathione; Isoleucine; Ligases; Phosphotransferases; Research; RNA; Triticum; Valine | 1963 |
THE EXCHANGE OF 14CO2 WITH BRANCHED-CHAIN KETOACIDS BY GUINEA-PIG LIVER.
Topics: Carbon Dioxide; Carbon Isotopes; Digestion; Guinea Pigs; Isoleucine; Keto Acids; Leucine; Liver; Maple Syrup Urine Disease; Metabolism; Research; Valine | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
MAPLE SYRUP URINE DISEASE.
Topics: Blood Chemical Analysis; Chromatography; Diet; Diet Therapy; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolism; Physiology; Valine | 1964 |
CHROMATOGRAPHIC SEPARATION OF AMINO ACID ISOMERS.
Topics: Amino Acids; Chromatography; Hydroxyproline; Isoleucine; Leucine; Research; Valine | 1964 |
A DETERMINATION OF THE ESSENTIAL AMINO ACID PROPORTIONS NEEDED TO ALLOW RAPID GROWTH IN CHICKS.
Topics: Amino Acids; Amino Acids, Essential; Animals; Animals, Newborn; Arginine; Caseins; Chickens; Cystine; Diet; Dietary Proteins; Glutamates; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Poultry; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
RELATIVE POTENCY OF DIETS CONTAINING AMINO ACIDS AND PROTEINS FOR PROMOTING GROWTH OF RATS.
Topics: Albumins; Amino Acids; Animals, Newborn; Arginine; Cystine; Diet; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Rats; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE AMINO ACIDS COMPOSITION AND NUTRITIVE VALUE OF PROTEINS. V. AMINO ACID REQUIREMENTS AS A PATTERN FOR PROTEIN EVALUATION.
Topics: Albumins; Amino Acids; Caseins; Cystine; Dietary Proteins; Gelatin; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Physiological Phenomena; Nutritional Sciences; Nutritive Value; Ovalbumin; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[COMPARATIVE EFFECTS OF DEPRIVATION OF VARIOUS ESSENTIAL AMINO ACIDS ON BASAL METABOLISM IN THE MALE RAT].
Topics: Amino Acids, Essential; Arginine; Basal Metabolism; Diet; Isoleucine; Nitrogen; Protein Deficiency; Rats; Research; Threonine; Valine | 1963 |
[CLINICAL, BIOCHEMICAL, AND NEUROPATHOLOGIC ASPECTS OF MAPLE SYRUP URINE DISEASE. A KETOACIDURIA OF THE OPEN CHAIN AMINOACIDS LEUCINE, ISOLEUCINE AND VALINE].
Topics: Amino Acids; Genetics, Medical; Humans; Infant; Isoleucine; Keto Acids; Ketosis; Leucine; Maple Syrup Urine Disease; Nervous System Diseases; Neurosciences; Pathology; Valine | 1963 |
MAPLE SYRUP URINE DISEASE.
Topics: Amino Acids; Blood Chemical Analysis; Body Fluids; Cerebrospinal Fluid; Chromatography; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Urine; Valine | 1964 |
[HISTOLOGICAL STUDIES OF NUCLEIC ACIDS OF THE LIVER IN DIETARY LIVER DISORDERS. 3. RESULTS WITH A DIET OF BUCKWHEAT FLOUR WITH ADDED AMINO ACIDS].
Topics: Amino Acids; Arginine; Diet; Edible Grain; Fagopyrum; Fatty Liver; Flour; Histidine; Isoleucine; Leucine; Lipotropic Agents; Liver; Lysine; Methionine; Mice; Phenylalanine; Research; RNA; Threonine; Tryptophan; Valine | 1964 |
GENETIC AND BIOCHEMICAL ANALYSIS OF ISOLEUCINE-VALINE MUTANTS OF YEAST.
Topics: Biochemical Phenomena; Biochemistry; Genetics; Isoleucine; Isomerases; Proteins; Research; Saccharomyces; Transaminases; Valine | 1964 |
EFFECT OF AMINO ACIDS ON UPTAKE OF L-HISTIDINE BY RAT BRAIN SLICES.
Topics: Amino Acids; Arginine; Brain; Chromatography; Culture Media; Cysteine; Cystine; Dipeptides; Glutamates; Histidine; Hydroxyproline; Isoleucine; Leucine; Metabolism; Phenylalanine; Pimelic Acids; Proline; Rats; Research; Taurine; Tryptophan; Valine | 1964 |
REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. I. GENETIC DEREPRESSION OF ENZYME FORMATION.
Topics: Drug Resistance; Drug Resistance, Microbial; Enzymes; Escherichia coli; Escherichia coli K12; Genetics; Hydro-Lyases; Isoleucine; Mutation; Protein Biosynthesis; Research; Threonine; Transaminases; Valine | 1964 |
FURTHER OBSERVATIONS OF A PATIENT WITH HYPERGLYCINEMIA.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Blood; Child; Diet; Diet Therapy; Glycine; Humans; Infections; Isoleucine; Leucine; Leukocyte Count; Methionine; Renal Aminoacidurias; Threonine; Toxicology; Valine | 1964 |
[STUDY, BY TRANSFORMATION, OF 2 GROUPS OF GENES GOVERNING THE BIOSYNTHESIS OF ISOLEUCINE, VALINE AND LEUCINE IN BACILLUS SUBTILIS].
Topics: Bacillus subtilis; Chromosomes; Isoleucine; Leucine; Proteins; Research; Valine | 1964 |
[PAPER CHROMATOGRAPHY OF SEVERAL BIOLOGICALLY IMPORTANT GUANIDINE COMPOUNDS].
Topics: Arginine; Canavanine; Chromatography; Chromatography, Paper; Creatine; Creatinine; Cystine; Guanidine; Guanidines; Isoleucine; Methionine; Research; Serine; Streptomycin; Tryptophan; Valine | 1964 |
AMINO-ACID DEPRIVATION AND BACTERIAL CELL-WALL SYNTHESIS.
Topics: Amino Acids; Bacteria; Electrons; Enterococcus faecalis; Histidine; Isoleucine; Leucine; Lysine; Microscopy; Microscopy, Electron; Proteins; Research; Threonine; Valine | 1963 |
CONTROL OF VALINE AND ISOLEUCINE METABOLISM IN PSEUDOMONAS AERUGINOSA AND ESCHERICHIA COLI.
Topics: Culture Media; Enzymes; Escherichia coli; Isoleucine; Keto Acids; Lactates; Proteins; Pseudomonas aeruginosa; Research; Threonine; Valine | 1964 |
ANTAGONISM OF POORLY INVERTIBLE D-AMINO ACIDS TOWARD GROWTH PROMOTION BY READILY INVERTIBLE D-AMINO ACIDS.
Topics: Amino Acids; Dietary Proteins; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rats; Research; Threonine; Tryptophan; Valine | 1964 |
ANTAGONISM OF THE D-FORMS OF THE ESSENTIAL AMINO ACIDS TOWARD THE PROMOTION OF GROWTH BY D-HISTIDINE.
Topics: Amino Acids; Amino Acids, Essential; Arginine; Dietary Proteins; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rats; Research; Threonine; Tryptophan; Valine | 1964 |
[NATURE OF THE ENZYME SYSTEMS RESPONSIBLE FOR NITROGEN-SOURCE AMINO ACID UTILIZATION IN BACILLUS SUBTILIS].
Topics: Alanine; Amidohydrolases; Amino Acid Oxidoreductases; Amino Acids; Aspartic Acid; Bacillus subtilis; Caproates; Glutamates; Isoleucine; Ketoglutaric Acids; Leucine; NAD; Nitrogen; Oxidoreductases; Proteins; Pyruvates; Research; Transaminases; Valerian; Valine | 1964 |
[STUDY OF FACTORS INVOLVED IN THE MASSIVE PRODUCTION OF BACILLUS SUBTILIS SPORES].
Topics: Alanine; Ammonium Chloride; Aspartic Acid; Bacillus subtilis; Carbon; Culture Media; Glutamates; Isoleucine; Nitrogen; Research; Spores, Bacterial; Valine | 1964 |
ACCUMULATION OF RIBONUCLEIC ACID IN BACTERIAL NUCLEAR PREPARATIONS DURING TREATMENT OF WHOLE CELLS WITH 8-AZAGUANINE, TETRACYCLINES, AND OTHER INHIBITORS.
Topics: Anti-Bacterial Agents; Antimetabolites; Azaguanine; Bacillus megaterium; Bacteriological Techniques; Chloramphenicol; Chlortetracycline; Ethionine; Isoleucine; Leucine; Mutation; Nitrogen; Oxytetracycline; Phenylalanine; Proteins; Research; RNA; Sulfur; Tetracyclines; Tryptophan; Tyrosine; Valine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
MAPLE SYRUP URINE DISEASE: A MANIFESTATION OF AN UNUSUAL METABOLIC ERROR.
Topics: Child; Genetics, Medical; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolism; Proteins; Valine | 1964 |
ON THE SITE OF ESTERIFICATION OF AMINO ACIDS TO SOLUBLE RNA.
Topics: Acetates; Adenine Nucleotides; Alanine; Amino Acids; Carbon Isotopes; Chromatography; Escherichia coli; Esterification; Glycerol; Glycine; Isoleucine; Leucine; Nucleosides; Phenylalanine; Pyrans; Research; RNA; RNA, Bacterial; Ultraviolet Rays; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE USE OF AMINO ACIDS AS STATIONARY PHASE IN GAS CHROMATOGRAPHY. 1. MONOSODIUM L-GLUTAMATE.
Topics: Alanine; Alcohols; Amino Acids; Chromatography; Chromatography, Gas; Fatty Acids; Glutamates; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Research; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
INCORPORATION OF L-ISOLEUCINE AND L-THREONINE INTO THE ACTINOMYCINS SYNTHESIZED BY STREPTOMYCES ANTIBIOTICUS.
Topics: Arginine; Carbon Isotopes; Chromatography; Culture Media; Dactinomycin; Glucose; Glycine; Isoleucine; Leucine; Metabolism; Methionine; Protein Hydrolysates; Proteins; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tryptophan; Valine | 1964 |
GENETIC BLOCKS IN THE ISOLEUCINE-VALINE PATHWAY OF NEUROSPORA CRASSA.
Topics: Genetics; Isoleucine; Isomerases; Keto Acids; Mutation; Neurospora; Neurospora crassa; Proteins; Pyruvates; Valine | 1964 |
[PHARMACEUTICAL AND CHEMICAL STUDIES ON INSULIN. (30) ON N-TERMINAL AMINO ACIDS AND CHEMICAL STRUCTURES OF BONITO AND TUNNY FISH INSULINS PURIFIED BY PRECIPITATION AT ISOELECTRIC POINT].
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography; Electrophoresis; Fishes; Glycine; Insulin; Isoelectric Point; Isoleucine; Lactobacillus; Research; Valine | 1963 |
[PHARMACEUTICAL AND CHEMICAL STUDIES ON INSULIN. (31) ON N- AND C-TERMINAL AMINO ACIDS OF CRYSTAL TA].
Topics: Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Fishes; Glycine; Insulin; Isoleucine; Lysine; Research; Serine; Valine | 1963 |
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
STIMULATION OF AMINO ACID INCORPORATION IN AN ESCHERICHIA COLI CELL-FREE SYSTEM BY RETICULOCYTE RNA.
Topics: Amino Acids; Carbon Isotopes; Cell-Free System; Chromatography; Escherichia coli; Isoleucine; Nucleoproteins; Proteins; Research; Reticulocytes; Ribosomes; RNA; RNA, Bacterial; Valine | 1964 |
TRANSAMINATION IN PERFUSED RAT LIVER.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Dioxide; Glutamates; Histidine; Isoleucine; Leucine; Liver; Metabolism; Methionine; Oxalates; Oxygen; Perfusion; Physiology; Potassium; Proteins; Pyruvates; Rats; Research; Valine; Water | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
AUTOREGULATION OF INTAKE OF AMINO-ACIDS: REVERSAL OF AN 'UNWISE' DIETARY PREFERENCE IN RATS UNDER CONDITIONS FAVOURABLE FOR LEARNING.
Topics: Amino Acids; Appetite; Caseins; Dietary Proteins; Discrimination Learning; Flavoring Agents; Homeostasis; Isoleucine; Leucine; Methionine; Rats; Research; Taste; Tryptophan; Valine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
INFLUENCE OF BETA-AMINOPROPIONITRILE ON DISSECTING ANEURYSM AND ON PLASMA AMINO ACIDS IN THE TURKEY.
Topics: Alanine; Amino Acids; Aminopropionitrile; Ammonia; Aneurysm; Animals; Aortic Dissection; Arginine; Autoanalysis; Blood; Chromatography; Collagen; Cyanides; Diet; Histidine; Isoleucine; Leucine; Lysine; Pharmacology; Poultry; Proline; Proteins; Research; Turkey; Valine | 1964 |
PREPARATION OF DERMATOPHYTES FOR AMINO ACID RESPIRATORY STUDIES.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Arthrodermataceae; Aspartic Acid; Glutamates; Isoleucine; Leucine; Metabolism; Microsporum; Phenylalanine; Research; Trichophyton; Valine | 1964 |
ENDOGENOUS RENAL CLEARANCES OF 12 INDIVIDUAL AMINO ACIDS IN FOUR APPARENTLY HEALTHY SUBJECTS AND IN FOUR AMINOACIDURIC PERSONS OF A KINDRED WITH HEREDITARY PANCREATITIS.
Topics: Amino Acids; Arginine; Biomedical Research; Cystine; Genetics, Medical; Glutamates; Healthy Volunteers; Histidine; Isoleucine; Kidney; Leucine; Lysine; Methionine; Pancreatitis; Pancreatitis, Chronic; Phenylalanine; Physiology; Renal Aminoacidurias; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
LATE MANIFESTING VARIANT OF BRANCHED-CHAIN KETOACIDURIA (MAPLE SYRUP URINE DISEASE).
Topics: Amino Acid Metabolism, Inborn Errors; Blood Proteins; Child; Chromatography; Cystine; Histidine; Humans; Infant; Isoleucine; Kidney; Leucine; Maple Syrup Urine Disease; Pathology; Renal Aminoacidurias; Valine | 1964 |
METABOLIC ANTAGONISM BETWEEN AN AZO DYE AND RIBOFLAVIN: EFFECT OF 3'-METHYL-4-MONOMETHYLAMINOAZOBENZENE ON MUTANTS OF NEUROSPORA CRASSA.
Topics: Adenine; Azo Compounds; Choline; Coloring Agents; Culture Media; Isoleucine; Lysine; Metabolism; Methionine; Neurospora; Neurospora crassa; Pharmacology; Research; Riboflavin; Valine | 1964 |
NUTRITION OF SALMONOID FISHES. XII. ISOLEUCINE, LEUCINE, VALINE AND PHENYLALANINE REQUIREMENTS OF CHINOOK SALMON AND INTER-RELATIONS BETWEEN ISOLEUCINE AND LEUCINE FOR GROWTH.
Topics: Animals; Fishes; Growth; Isoleucine; Leucine; Nutritional Physiological Phenomena; Nutritional Sciences; Nutritional Status; Pharmacology; Phenylalanine; Research; Salmon; Valine | 1964 |
[ACTIVATION OF ACELLULAR SYNTHESIS OF HEMOGLOBIN BY RIBONUCLEIC ACID. I. EFFECT OF TOTAL RIBONUCLEIC ACID ON RETICULOCYTES].
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Deoxyribonucleases; DNA; Escherichia coli; Guinea Pigs; Hemoglobins; Isoleucine; Leucine; Liver; Phenylalanine; Proteins; Rabbits; Research; Reticulocytes; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Valine; Yeasts | 1964 |
UROLITHIASIS IN THE RAT. IV. INFLUENCE OF AMINO ACID SUPPLEMENTS ON THE OCCURRENCE OF CITRATE CALCULI.
Topics: Amino Acids; Calcium; Caseins; Citrates; Citric Acid; Cystine; Dietary Proteins; Glutamates; Isoleucine; Kidney Calculi; Leucine; Lysine; Methionine; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
FACILITATORY EFFECT OF HIGH PROTEIN INTAKE ON SUBSEQUENT CONSUMPTION OF AN AMINO ACID IMBALANCED DIET.
Topics: Amino Acids; Caseins; Diet; Dietary Proteins; Isoleucine; Leucine; Methionine; Proteins; Rats; Research; Tryptophan; Valine | 1964 |
ISOLEUCINE AND VALINE METABOLISM IN ESCHERICHIA COLI. XII. CHARACTERIZATION OF A FACTOR INVOLVED IN ACETOLACTATE FORMATION.
Topics: Acetaldehyde; Acetates; Escherichia coli; Hydroxybutyrates; Isoleucine; Ketoglutaric Acids; Lactates; Metabolism; Pyridoxal Phosphate; Pyruvates; Research; Thiamine Pyrophosphate; Valine | 1964 |
VALINE-ISOLEUCINE METABOLISM IN ACETOBACTER SUBOXYDANS AND THE INHIBITION OF GROWTH BY VALINE.
Topics: Acetobacter; Amino Acids; Culture Media; Escherichia coli; Isoleucine; Leucine; Metabolism; Oregon; Pharmacology; Research; Threonine Dehydratase; Valine | 1964 |
INACTIVATION OF SOLUBLE RIBONUCLEIC ACID BY ELECTRON IRRADIATION.
Topics: Alanine; Amino Acids; Carbon Isotopes; Electrons; Isoleucine; Leucine; Liver; Methionine; Proline; Radiation Effects; Rats; Research; RNA; Saccharomyces; Tritium; Valine | 1964 |
MECHANISM OF AMINOACYL RNA SYNTHESIS: STUDIES WITH ISOLATED AMINOACYL ADENYLATE COMPLEXES OF ISOLEUCYL RNA SYNTHETASE.
Topics: Isoleucine; Ligases; Metabolism; Nucleotides; Peptide Hydrolases; Research; RNA; RNA Ligase (ATP); Valine | 1964 |
AMINO ACID CODING IN A SUBCELLULAR SYSTEM DERIVED FROM THE L1210 MOUSE ASCITES LEUKEMIA.
Topics: Adenine Nucleotides; Amino Acids; Animals; Ascites; Genetic Code; Isoleucine; Leucine; Leukemia L1210; Lysine; Neoplasm Proteins; Phenylalanine; Proteins; Research; Serine; Tyrosine; Valine | 1964 |
METHIONINE, VALINE AND ISOLEUCINE. REQUIREMENTS DURING INFANCY: GROWTH AND NITROGEN BALANCE STUDIES WITH NORMAL FULLTERM INFANTS RECEIVING SOYBEAN PROTEIN.
Topics: Dietary Proteins; Glycine max; Growth; Humans; Infant; Infant Nutritional Physiological Phenomena; Isoflavones; Isoleucine; Metabolism; Methionine; Nitrogen; Soybean Proteins; Valine | 1964 |
MAPLE SYRUP URINE DISEASE, WITH PARTICULAR REFERENCE TO DIETOTHERAPY.
Topics: Amino Acid Metabolism, Inborn Errors; Anthropometry; Blood Proteins; Cerebrospinal Fluid Proteins; Diet; Diet Therapy; Erythrocytes; Exchange Transfusion, Whole Blood; Growth; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Valine | 1964 |
BIOSYNTHESIS OF THE CYANOGENIC GLUCOSIDES LINAMARIN AND LOTAUSTRALIN. I. LABELING STUDIES IN VIVO WITH LINUM USITATISSIMUM.
Topics: Acetone; Alkaloids; Amides; Amines; Amino Acids; Autoradiography; Carbon Isotopes; Chromatography; Cyanides; Fatty Acids; Flax; Glucosides; Glutarates; Glycosides; Hydroxybutyrates; Isoleucine; Nitriles; Plants; Research; Seeds; Thiocyanates; Tritium; Valine | 1964 |
MAPLE-SYRUP-URINE DISEASE. REPORT OF A CASE, WITH A PEDIGREE.
Topics: Acer; Body Fluids; Chromatography; Diet; Diet Therapy; Gelatin; Genetics, Medical; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Leucine; Maple Syrup Urine Disease; Pedigree; Urine; Valine | 1964 |
THE DEVELOPMENTAL SIGNIFICANCE OF ALANINE DEHYDROGENASE IN BACILLUS SUBTILIS.
Topics: Alanine; Alanine Dehydrogenase; Alanine Transaminase; Amino Acid Oxidoreductases; Amino Acids; Aminobutyrates; Ammonia; Aspartate Aminotransferases; Bacillus subtilis; Cysteine; Isoleucine; Leucine; Lyases; Methionine; Mutation; Research; Serine; Spectrophotometry; Spores; Spores, Bacterial; Valine | 1964 |
STUDIES ON THE ROLE OF METHYLATED BASES IN THE BIOLOGICAL ACTIVITY OF SOLUBLE RIBONUCLEIC ACID.
Topics: Alkylation; Amino Acids; Arginine; Carbon Isotopes; Histidine; Isoleucine; Kinetics; Leucine; Metabolism; Methionine; Phenylalanine; Purines; Pyrimidines; Research; RNA; Tyrosine; Valine | 1964 |
RECOMBINATION BETWEEN NOCARDIA ERYTHROPOLIS AND NOCARDIA CANICRURIA.
Topics: Adenine; Alanine; Anti-Bacterial Agents; Arginine; Cysteine; Cystine; Drug Resistance; Drug Resistance, Microbial; Glycine; Guanine; Histidine; Hypoxanthines; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Mutation; Nocardia; Recombination, Genetic; Research; Streptomycin; Valine; Xanthines | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
EFFECT OF GLUCOSE INFUSION ON THE INDIVIDUAL PLASMA FREE AMINO ACIDS IN MAN.
Topics: Amino Acids; Blood; Glucose; Humans; Insulin; Isoleucine; Leucine; Male; Pharmacology; Phenylalanine; Threonine; Tyrosine; Valine | 1964 |
[ON THE ALLOSTERIC PROPERTIES OF BIOSYNTHETIC L-THREONINE DEAMINASE. 3. INTERPRETATION OF THE INHIBITORY EFFECT OF L-ISOLEUCINE: STERIC HINDRANCE OR ALLOSTERIC EFFECT].
Topics: Amino Acids; Aminohydrolases; Antimetabolites; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoleucine; Models, Theoretical; Research; Threonine; Threonine Dehydratase; Valine | 1964 |
COMPARATIVE RADIOLABILITY OF AMINO ACIDS OF PROTEINS AND FREE AMINO ACIDS.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Catalase; Chromatography; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Ovalbumin; Phenylalanine; Proteins; Radiation Effects; Research; Serine; Valine | 1964 |
LACK OF FIDELITY IN THE TRANSLATION OF SYNTHETIC POLYRIBONUCLEOTIDES.
Topics: Bacillus; Dihydrostreptomycin Sulfate; Isoleucine; Leucine; Magnesium; Metabolism; Nucleotides; Phenylalanine; Polyribonucleotides; Proteins; Research; RNA; RNA, Messenger; Serine; Spermine; Temperature; Tyrosine; Valine | 1964 |
ISOLEUCINE-VALINE REQUIRING MUTANTS OF SALMONELLA TYPHIMURIUM.
Topics: Genes; Genetics; Isoleucine; Mutation; Proteins; Research; Salmonella typhimurium; Valine | 1964 |
CHARACTERISTICS OF THE INHIBITION OF HEMOGLOBIN SYNTHESIS IN RABBIT RETICULOCYTES BY THREO-ALPHA-AMINO-BETA-CHLOROBUTYRIC ACID.
Topics: Amino Acids; Animals; Hemoglobins; Isoleucine; Proteins; Rabbits; Research; Reticulocytes; Ribosomes; Valine | 1964 |
CONTROL OF ISOLEUCINE, VALINE AND LEUCINE BIOSYNTHESIS. II. ENDPRODUCT INHIBITION BY VALINE OF ACETOHYDROXY ACID SYNTHETASE IN SALMONELLA TYPHIMURIUM.
Topics: Acetolactate Synthase; Amino Acids; Butyrates; Enzyme Inhibitors; Glutathione; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Lactates; Leucine; Ligases; Magnesium; Mercury; Pyruvates; Research; Salmonella typhimurium; Thiamine Pyrophosphate; Urea; Valine | 1964 |
A SIMPLIFIED METHOD FOR THE DETERMINATION OF ISOLEUCINE AND ITS SIX-CARBON PRECURSORS.
Topics: Alanine; Amino Acids; Aminobutyrates; Bacillus subtilis; Carbon; Escherichia coli; Fatty Acids; Hydroxybutyrates; Isoleucine; Keto Acids; Leucine; Lysine; Methionine; Research; Threonine; Valine | 1964 |
BIOSYNTHESIS OF VALINE AND ISOLEUCINE IN PLANTS. II. DIHYDROXYACID DEHYDRATASE FROM PHASEOLUS RADIATUS.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography; Enzyme Inhibitors; Ethylmaleimide; Hydro-Lyases; Iron; Isoleucine; Kinetics; Magnesium; Manganese; Mercury; Phaseolus; Plants; Research; Silver; Sulfhydryl Compounds; Valine | 1964 |
BIOCHEMICAL AND GENETIC GROUPING OF ISOLEUCINE-VALINE MUTANTS OF PSEUDOMONAS AERUGINOSA.
Topics: Amino Acids; Bacteriophages; Chromosome Mapping; Genes; Genetic Linkage; Isoleucine; Mutation; New Zealand; Pseudomonas aeruginosa; Research; Threonine; Ultraviolet Rays; Valine | 1965 |
[TRANSFORMING ACTIVITY OF DESOXYRIBONUCLEIC ACID FROM BACILLUS SUBTILIS AT THE TIME OF THYMINE DEFICIENCY].
Topics: Bacillus subtilis; Bacteriophages; DNA; DNA, Bacterial; Isoleucine; Metabolism; Molecular Biology; Mutation; Research; Thymine; Tryptophan; Valine | 1964 |
THE SEPARATION AND PARTIAL PURIFICATION OF AMINOACYL-RNA SYNTHETASES FROM ESCHERICHIA COLI.
Topics: Amino Acids; Chromatography; Cysteine; Diphosphates; Escherichia coli; Isoleucine; Leucine; Ligases; Methionine; Phosphorus Isotopes; Research; RNA; RNA-Dependent RNA Polymerase; RNA, Bacterial; Tryptophan; Tyrosine; Valine | 1964 |
[SEX-SPECIFIC DIFFERENCES OF SERUM AMINO ACID CONCENTRATIONS].
Topics: Amino Acids; Biomedical Research; Blood; Chromatography; Cystine; Isoleucine; Leucine; Phenylalanine; Pregnancy; Sex; Tyrosine; Valine | 1965 |
REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. II. IDENTIFICATION OF TWO OPERATOR GENES.
Topics: Amino Acids; Aminobutyrates; Aminohydrolases; Enzyme Repression; Escherichia coli; Genes; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Mutation; Oxidoreductases; Research; Threonine; Transaminases; Valine | 1965 |
REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. 3. MAP ORDER OF THE STRUCTURAL GENES AND OPERATOR GENES.
Topics: Amino Acids; Aminohydrolases; Bacteriophages; Escherichia coli; Genes; Hydro-Lyases; Isoleucine; Isomerases; Mutation; Oxidoreductases; Research; Threonine; Transaminases; Valine | 1965 |
PERIODONTAL PATHOSIS IN MAN X. EFFECT OF COMBINED VERSUS ANIMAL PROTEIN SUPPLEMENTATION UPON SULCUS DEPTH.
Topics: Biomedical Research; Dietary Proteins; Isoleucine; Leucine; Methionine; Periodontal Diseases; Phenylalanine; Placebos; Threonine; Tryptophan; Valine | 1965 |
A SOLUBLE RIBONUCLEIC ACID-INDUCED INCREASE IN THE SPECIFICITY OF ESCHERICHIA COLI ISOLEUCINE-ACTIVATING ENZYME.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Hydroxamic Acids; Isoleucine; Ligases; Radiometry; Research; RNA; Valine | 1965 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. I. ALANINE, GLYCINE, VALINE, LEUCINE, ISOLEUCINE, SERINE AND THREONINE.
Topics: Alanine; Arginine; Chromatography; Chromatography, Gas; Equipment and Supplies; Glycine; Isoleucine; Leucine; Research; Serine; Threonine; Valine | 1965 |
GRAMICIDIN A. V. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN A.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Gramicidin; Isoleucine; Peptides; Research; Valine | 1965 |
GRAMICIDIN A. VI. THE SYNTHESIS OF VALINE- AND ISOLEUCINE-GRAMICIDIN A.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Gramicidin; Isoleucine; Peptides; Research; Valine | 1965 |
GRAMICIDIN. VII. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN B.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Gramicidin; Isoleucine; Peptides; Research; Valine | 1965 |
ENZYMATIC PROPERTIES OF ALANINE DEHYDROGENASE OF BACILLUS SUBTILIS.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acids; Aminobutyrates; Bacillus subtilis; Benzoates; Caproates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Isoleucine; Ketoglutaric Acids; Metals; NAD; Oxalates; Pyruvates; Research; Serine; Valine | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
RELATION OF BIOCHEMICAL MUTATIONS TO ACTINOMYCIN SYNTHESIS IN STREPTOMYCES ANTIBIOTICUS.
Topics: Adenine; Amino Acids; Arginine; Culture Media; Cysteine; Dactinomycin; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Mutation; Phenylalanine; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tyrosine; Ultraviolet Rays; Uracil; Valine | 1965 |
"SELFING" AND OTHER FORMS OF ABERRANT RECOMBINATION IN ISOLEUCINE-VALINE MUTANTS OF NEUROSPORA.
Topics: Chromosomes; Isoleucine; Lysine; Mutation; Neurospora; Recombination, Genetic; Research; Valine | 1965 |
STUDIES ON THE EFFECT OF TRYPTOPHAN DEFICIENCY ON THE METABOLIC PRODUCTS OF TRYPTOPHAN AND NIACIN.
Topics: Amino Acids; Blood; Creatine; Creatinine; Deficiency Diseases; Diet; Fluids and Secretions; Histidine; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Niacin; Niacinamide; Nitrogen; Nucleotides; Phenylalanine; Riboflavin; Tryptophan; Urine; Valine; Xanthurenates | 1965 |
PLASMA GROWTH HORMONE RESPONSE TO INTRAVENOUS ADMINISTRATION OF AMINO ACIDS.
Topics: Administration, Intravenous; Amino Acids; Arginine; Biomedical Research; Blood; Blood Glucose; Fasting; Growth Hormone; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Threonine; Valine | 1965 |
LINKAGE RELATIONSHIPS OF GENES CONTROLLING ISOLEUCINE, VALINE, AND LEUCINE BIOSYNTHESIS IN BACILLUS SUBTILIS.
Topics: Amino Acids; Aminohydrolases; Arginine; Bacillus subtilis; Bacteriophages; Chromosome Mapping; DNA; DNA, Bacterial; France; Genes; Genetic Linkage; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Oxidoreductases; Phenylalanine; Research; Threonine; Ultraviolet Rays; Valine | 1965 |
[ON THE ALLOSTERIC OF BIOSYNTHESIZED L-THREONINE DEAMINASE. IV. THE DESENSITIZATION PHENOMENON].
Topics: Aminohydrolases; Biochemical Phenomena; Biochemistry; Enzyme Inhibitors; Escherichia coli; Hot Temperature; Isoleucine; Kinetics; Leucine; Mercaptoethanol; Mercury; Mutation; Research; Sulfhydryl Compounds; Threonine; Threonine Dehydratase; Valine | 1965 |
BITTER PEPTIDE ISOLATED FROM MILK CULTURES OF STREPTOCOCCUS CREMORIS.
Topics: Alanine; Amino Acids; Arginine; Butanones; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Culture Media; Electrophoresis; Glutamates; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Milk; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Research; Streptococcus; Threonine; Tyrosine; Valine | 1965 |
THE ISOLATION OF AMINO ACIDS FROM MIXTURES AS THEIR N-2,4-DINITROPHENYL DERIVATIVES, METHIONINE, LEUCINE, PHENYLALANINE, ORNITHINE, LYSINE AND TYROSINE.
Topics: Amino Acids; Chromatography; Dinitrophenols; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Research; Tyrosine; Valine | 1965 |
THE STIMULATION BY TREATMENT IN VIVO WITH TRI-IODOTHYRONINE OF AMINO ACID INCORPORATION INTO PROTEIN BY ISOLATED RAT-LIVER MITOCHONDRIA.
Topics: Acid Phosphatase; Adenosine Triphosphate; Amino Acids; Animals; Glucose-6-Phosphatase; Isoleucine; Leucine; Liver; Malate Dehydrogenase; Metabolism; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Pharmacology; Proteins; Rats; Research; RNA; Succinate Dehydrogenase; Thyroidectomy; Triiodothyronine; Valine | 1965 |
AMINO ACID SENSITIVITY OF STRAINS DERIVED FROM ESCHERICHIA COLI K 12.
Topics: Amino Acids; Bacteriological Techniques; Escherichia coli; Feedback; Genetics; Glycine; Growth; Isoleucine; Leucine; Methionine; Pharmacology; Proline; Research; Serotonin; Threonine; Tyrosine; Valine | 1965 |
THE SYNTHESIS IN VITRO OF VALINE AND ISOLEUCINE FROM PYRUVATE AND ALPHA-KETOBUTYRATE IN NEUROSPORA.
Topics: Amino Acids; Butyrates; In Vitro Techniques; Isoleucine; Keto Acids; Neurospora; Pyruvates; Pyruvic Acid; Research; Valine | 1965 |
ACETOLACTATE METABOLISM AND THE PRESENCE OF A DIHYDROXY ACID DEHYDRATASE IN MICRO-ORGANISMS.
Topics: Acetobacter; Amino Acids; Bacillus subtilis; Biochemical Phenomena; Biochemistry; Hydro-Lyases; Isoleucine; Ketones; Lactates; Lyases; Metabolism; Proteus; Research; Staphylococcus; Staphylococcus aureus; Valine | 1965 |
The specific amino acid requirements of a human carcinoma cell (Stain HeLa) in tissue culture.
Topics: Amino Acids; Animals; Arginine; Coloring Agents; Female; HeLa Cells; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Neoplasms, Experimental; Phenylalanine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Uterine Neoplasms; Uterus; Valine | 1955 |
Influence of valine, isoleucine, and related compounds on actinomycin synthesis.
Topics: Dactinomycin; Isoleucine; Leucine; Valine | 1960 |
Amino acid requirement for maintenance in the adult rooster. III. The requirements for leucine, isoleucine, valine and threonine, with reference also to the utilization of the D-isomers of valine, threonine and isoleucine.
Topics: Amino Acids; Animals; Chickens; Diet; Isoleucine; Leucine; Male; Nutrition Assessment; Nutritional Status; Poultry; Threonine; Valine | 1960 |
Detection of 2:4-dinitrophenyl amino-acids on paper chromatograms.
Topics: Amino Acids; Chromatography, Paper; Isoleucine; Leucine; Valine | 1959 |
Valine and isoleucine metabolism of Streptomyces rimosus.
Topics: Biochemical Phenomena; Isoleucine; Streptomyces; Streptomyces rimosus; Valine | 1962 |
Role of valine and isoleucine as regulators of actinomycin peptide formation by Streptomyces chrysomallus.
Topics: Amino Acids; Dactinomycin; Isoleucine; Leucine; Peptides; Streptomyces; Threonine; Valine | 1961 |
Biosynthesis of valine and isoleucine in the wheat plant.
Topics: Biochemical Phenomena; Isoleucine; Leucine; Plant Oils; Triticum; Valine | 1962 |
Isoleucine and valine metabolism in Escherichia coli. XI. Valine inhibition of the growth of Escherichia coli strain K-12.
Topics: Amino Acids; Escherichia coli; Hydroxybutyrates; Isoleucine; Valine | 1962 |
Spectrometric evaluation of the approximate pK of the carboxyl group in 2,4-dinitrophenyl-amino acids.
Topics: Amino Acids; Isoleucine; Leucine; Nitrophenols; Spectrum Analysis; Valine | 1962 |
Biosynthesis of valine and isoleucine in plants.
Topics: Biochemical Phenomena; Isoleucine; Leucine; Plants; Valine | 1962 |
Relationship between glutathione S-transferase P1 polymorphism and bronchial asthma and atopic dermatitis.
Topics: Alleles; Asthma; Child; Dermatitis, Atopic; Female; Genotype; Glutathione Transferase; Homozygote; Humans; Isoleucine; Male; Odds Ratio; Polymorphism, Genetic; Risk; Russia; Valine; Xenobiotics | 2003 |
Amprenavir resistance imparted by the I50V mutation in HIV-1 protease can be suppressed by the N88S mutation.
Topics: Asparagine; Carbamates; Drug Resistance, Viral; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Isoleucine; Microbial Sensitivity Tests; Mutation; Serine; Sulfonamides; Valine | 2003 |
Unique lipoprotein phenotype and genotype associated with exceptional longevity.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Carrier Proteins; Case-Control Studies; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Codon; Female; Genotype; Glycoproteins; Humans; Hypertension; Isoleucine; Jews; Lipoproteins; Longevity; Male; Metabolic Syndrome; Particle Size; Phenotype; Polymorphism, Genetic; Valine | 2003 |
Ile, Leu, and Val methyl assignments of the 723-residue malate synthase G using a new labeling strategy and novel NMR methods.
Topics: Carbon Isotopes; Isoleucine; Leucine; Malate Synthase; Nuclear Magnetic Resonance, Biomolecular; Protons; Valine | 2003 |
Hydrogen-bond cooperativity, vibrational coupling, and dependence of helix stability on changes in amino acid sequence in small 3 10-helical peptides. A density functional theory study.
Topics: Alanine; Amino Acids; Computer Simulation; Isoleucine; Leucine; Models, Molecular; Oligopeptides; Peptides; Protein Structure, Secondary; Thermodynamics; Valine | 2003 |
Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Isoleucine; Lung Neoplasms; Male; Mutation, Missense; Occupational Exposure; Poland; Polymorphism, Genetic; Risk Factors; Smoking; Valine | 2003 |
Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes.
Topics: Administration, Oral; Amino Acids; Animals; Blood Glucose; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glucose Tolerance Test; Isoleucine; Leucine; Male; Muscle Fibers, Skeletal; Myoblasts; Plasma; Rats; Rats, Sprague-Dawley; Valine | 2003 |
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallization; Crystallography, X-Ray; Gene Expression; Isoleucine; Isoleucine-tRNA Ligase; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis; Peptide Fragments; RNA Editing; RNA, Transfer, Amino Acyl; Sequence Alignment; Structure-Activity Relationship; Thermus thermophilus; Transfection; Valine | 2004 |
Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N.
Topics: Alanine; Anti-HIV Agents; Asparagine; Aspartic Acid; Binding Sites; Drug Resistance, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoleucine; Kinetics; Methionine; Mutagenesis, Site-Directed; Nelfinavir; Ritonavir; Valine | 2003 |
Central administration of leucine, but not isoleucine and valine, stimulates feeding behavior in neonatal chicks.
Topics: Animals; Animals, Newborn; Appetite Regulation; Brain; Chickens; Feeding Behavior; Glutamic Acid; Hyperphagia; Isoleucine; Keto Acids; Leucine; Male; Reaction Time; Valine | 2004 |
Parenteral and enteral routes of feeding in neonatal piglets require different ratios of branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Animals; Animals, Newborn; Enteral Nutrition; Isoleucine; Leucine; Male; Oxidation-Reduction; Parenteral Nutrition; Phenylalanine; Swine; Valine; Weight Gain | 2004 |
Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase.
Topics: Binding Sites; Deuterium; Escherichia coli Proteins; Folic Acid; Isoleucine; NADP; Nanotechnology; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Tertiary; Spectrophotometry; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Thermodynamics; Threonine; Valine | 2004 |
Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Arabidopsis; Electrophoresis, Gel, Two-Dimensional; Isoleucine; Keto Acids; Ketoglutarate Dehydrogenase Complex; Leucine; Mass Spectrometry; Mitochondria; Multienzyme Complexes; Oryza; Oxidation-Reduction; Oxygen Consumption; Pisum sativum; Plant Proteins; Proteomics; Pyruvate Dehydrogenase Complex; Thioctic Acid; Valine | 2004 |
The separation of N-2:4-dinitrophenly amino-acids on paper chromatograms.
Topics: Amino Acids; Chromatography; Isoleucine; Leucine; Valine | 1951 |
Isoleucine and valine metabolism of Escherichia coli. I. Growth studies on amino acid-deficient mutants.
Topics: Amino Acids; Escherichia coli; Isoleucine; Leucine; Valine | 1951 |
Isoleucine and valine metabolism of Escherichia coli. II. The accumulation of keto acids.
Topics: Escherichia coli; Isoleucine; Keto Acids; Leucine; Valine | 1951 |
Origin of the carbon skeletons of isoleucine and valine.
Topics: Carbon; Isoleucine; Valine | 1951 |
[Competitive inhibition of the growth of a mutant of Escherichia coli requiring valine by L-isoleucine and the non-competitive reversal of the inhibition by L-leucine].
Topics: Biological Phenomena; Escherichia coli; Isoleucine; Leucine; Physiological Phenomena; Valine | 1951 |
Glycyl dehydropeptides of leucine, valine, and isoleucine.
Topics: Fabaceae; Glycine; Isoleucine; Leucine; Peptides; Valine | 1952 |
Amino Amino-acid composition of Indian foodstuffs. Part I. Tryptophan, leucine, isoleucine and valine content of some cereals.
Topics: Amino Acids; Edible Grain; Isoleucine; Leucine; Tryptophan; Valine | 1952 |
A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles.
Topics: Amino Acid Substitution; Animals; Bacillus subtilis; Bacterial Proteins; Binding Sites; Catalysis; Conserved Sequence; Heme; Iron; Isoleucine; Kinetics; Mice; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Valine | 2004 |
The Aalpha-chain 6Ile/Val polymorphism is not associated with plasma fibrinogen levels in Japanese.
Topics: Adult; Amino Acid Substitution; Base Sequence; DNA Primers; Female; Fibrinogen; Humans; Isoleucine; Leukemia, Promyelocytic, Acute; Mutation, Missense; Polymorphism, Genetic; Valine | 2003 |
Thermodynamics of core hydrophobicity and packing in the hyperthermophile proteins Sac7d and Sso7d.
Topics: Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Calorimetry, Differential Scanning; Circular Dichroism; DNA-Binding Proteins; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Protein Structure, Secondary; Sequence Homology, Amino Acid; Sulfolobus acidocaldarius; Thermodynamics; Valine | 2004 |
Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms.
Topics: Age of Onset; Aged; alpha-Macroglobulins; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Chi-Square Distribution; Confidence Intervals; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Italy; Male; Middle Aged; Odds Ratio; Peroxidase; Polymerase Chain Reaction; Polymorphism, Genetic; Risk; Valine | 2004 |
Blood serum branched chain amino acids and tryptophan modifications in horses competing in long-distance rides of different length.
Topics: Amino Acids, Branched-Chain; Analysis of Variance; Animals; Horses; Isoleucine; Leucine; Physical Conditioning, Animal; Physical Endurance; Sports; Tryptophan; Valine | 2004 |
A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
Topics: Amino Acid Substitution; Asparagine; Bacteriophage M13; Base Pair Mismatch; Binding Sites; Deoxyribonucleotides; DNA Primers; Gene Frequency; Glutamine; HIV Reverse Transcriptase; HIV-1; Isoleucine; Kinetics; Lac Operon; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Substrate Specificity; Templates, Genetic; Valine | 2004 |
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus.
Topics: Cell Membrane; Chromatography; Culture Media; Fatty Acids; Flavoring Agents; Food Microbiology; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Meat Products; Oxidation-Reduction; Pentanoic Acids; Pyruvic Acid; Staphylococcus; Valine | 2004 |
A conditional marker gene allowing both positive and negative selection in plants.
Topics: Alanine; Arabidopsis; Catalysis; D-Amino-Acid Oxidase; DNA; Dose-Response Relationship, Drug; Genetic Markers; Genetic Techniques; Genetic Vectors; Hemiterpenes; Isoleucine; Keto Acids; Oxygen; Plants; Plants, Genetically Modified; RNA; Serine; Transgenes; Valine | 2004 |
Structure and solvation of melittin in 1,1,1,3,3,3-hexafluoro-2-propanol/water.
Topics: Alcohols; Animals; Bee Venoms; Bees; Biophysics; Chromatography, High Pressure Liquid; Fluorine; Glutamine; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Melitten; Models, Molecular; Peptides; Propanols; Protein Conformation; Protons; Solvents; Spectrophotometry; Temperature; Valine; Water | 2004 |
Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
Topics: Age Factors; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Blotting, Southern; Brain Chemistry; Choice Behavior; Disease Models, Animal; Female; Genotype; Humans; Immunohistochemistry; Isoleucine; Male; Maze Learning; Mice; Mice, Transgenic; Molecular Sequence Data; Motor Activity; Mutation; Neurofibrillary Tangles; Peptide Fragments; Reaction Time; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors; Survival Rate; tau Proteins; Valine | 2004 |
Crystallization and preliminary X-ray analysis of alpha-isopropylmalate synthase from Mycobacterium tuberculosis.
Topics: 2-Isopropylmalate Synthase; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Isoleucine; Mycobacterium tuberculosis; Open Reading Frames; Recombinant Proteins; Selenomethionine; Valine; X-Ray Diffraction | 2004 |
A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.
Topics: Adipose Tissue; Adult; Alleles; Carbohydrate Metabolism; Fatty Acid Synthases; Gene Frequency; Genetic Variation; Humans; Indians, North American; Isoleucine; Mutation, Missense; Obesity; Oxidation-Reduction; Valine | 2004 |
Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate.
Topics: Animals; Carrier Proteins; Food Deprivation; Intracellular Signaling Peptides and Proteins; Isoleucine; Keto Acids; Leucine; Liver; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 90-kDa; Stereoisomerism; Valine | 2004 |
Activation of the Bacillus subtilis global regulator CodY by direct interaction with branched-chain amino acids.
Topics: Adaptation, Physiological; Amino Acids, Branched-Chain; Artificial Gene Fusion; Bacillus subtilis; Bacterial Proteins; Base Sequence; beta-Galactosidase; DNA Footprinting; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Enzyme Activators; Gene Expression Regulation, Bacterial; Genes, Reporter; Guanosine Triphosphate; Isoleucine; Lac Operon; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Valine | 2004 |
Intracellular effectors regulating the activity of the Lactococcus lactis CodY pleiotropic transcription regulator.
Topics: Adaptation, Physiological; Amino Acids, Branched-Chain; Bacillus subtilis; Bacterial Proteins; beta-Galactosidase; DNA-Binding Proteins; Enzyme Activators; Gene Expression Regulation, Bacterial; Genes, Reporter; Guanosine Triphosphate; Isoleucine; Lac Operon; Lactococcus lactis; Leucine; Luciferases; Operon; Promoter Regions, Genetic; Repressor Proteins; Valine | 2004 |
Alternative translations of a single RNA message: an identity switch of (2S,3R)-4,4,4-trifluorovaline between valine and isoleucine codons.
Topics: Codon; Gene Expression; Isoleucine; RNA; RNA, Transfer; Stereoisomerism; Valine | 2004 |
Different conformational changes within the F-helix occur during serpin folding, polymerization, and proteinase inhibition.
Topics: alpha 1-Antitrypsin; Humans; Isoleucine; Mutagenesis, Site-Directed; Peptide Fragments; Polymers; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine Proteinase Inhibitors; Serpins; Thermodynamics; Valine | 2004 |
Recruitment of the ArgR/Mcm1p repressor is stimulated by the activator Gcn4p: a self-checking activation mechanism.
Topics: Arginine; DNA-Binding Proteins; Feedback, Physiological; Gene Expression Regulation, Fungal; Isoleucine; Macromolecular Substances; Minichromosome Maintenance 1 Protein; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Kinases; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transcription, Genetic; Valine | 2004 |
Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation.
Topics: Asparagine; Cell Line; Codon; Gene Expression Regulation; Genetic Variation; Humans; Isoleucine; Lysine; Mutation; Receptor, Melanocortin, Type 3; Receptors, G-Protein-Coupled; Receptors, LH; Threonine; Valine | 2004 |
The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain.
Topics: Adult; Aged; Alleles; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Fatty Acids, Nonesterified; Finland; Gene Frequency; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Isoleucine; Middle Aged; Oxidation-Reduction; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prospective Studies; Receptor, Melanocortin, Type 4; Sequence Analysis, DNA; Valine; Weight Gain | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.
Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blood Coagulation; Blood Platelets; Cell Line; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor IXa; Factor VIIIa; Factor X; Humans; Isoleucine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Platelet Activation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors; Valine | 2004 |
Treatment with leucine stimulates the production of hepatocyte growth factor in vivo.
Topics: Animals; Hepatocyte Growth Factor; Injections, Intraperitoneal; Isoleucine; Kinetics; Leucine; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Serum Albumin; Starvation; Valine | 2004 |
[Analysis of the glutathione S-transferase P1 gene Ile105Val polymorphism in the patients with sporadic motor neuron disease from Russia].
Topics: Alleles; Base Sequence; DNA Primers; Gene Frequency; Genotype; Glutathione Transferase; Humans; Isoleucine; Motor Neuron Disease; Polymorphism, Genetic; Russia; Valine | 2004 |
An IL-4R alpha allelic variant, I50, acts as a gain-of-function variant relative to V50 for Stat6, but not Th2 differentiation.
Topics: Alleles; Animals; Cell Differentiation; DNA-Binding Proteins; Genetic Variation; Growth Inhibitors; Humans; Interleukin-4; Interleukin-4 Receptor alpha Subunit; Isoleucine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutagenesis, Site-Directed; Protein Subunits; Receptors, Cell Surface; Receptors, Interleukin-4; Signal Transduction; STAT6 Transcription Factor; Th1 Cells; Th2 Cells; Trans-Activators; Transcription, Genetic; Up-Regulation; Valine | 2004 |
RNA editing of a human potassium channel modifies its inactivation.
Topics: Amino Acid Substitution; Humans; Isoleucine; Kv1.1 Potassium Channel; Potassium Channels; Potassium Channels, Voltage-Gated; RNA Editing; Valine | 2004 |
Prevalence of the GJB2 mutations and the del(GJB6-D13S1830) mutation in Brazilian patients with deafness.
Topics: Brazil; Connexin 26; Connexins; Deafness; Female; Gene Deletion; Gene Frequency; Guanine; Hearing Loss, Sensorineural; Heterozygote; Humans; Isoleucine; Male; Minisatellite Repeats; Mutation; Valine | 2004 |
Effect of plasma insulin and branched-chain amino acids on skeletal muscle protein synthesis in fasted lambs.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Food Deprivation; Glucose; Infusions, Intravenous; Insulin; Isoleucine; Leucine; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Sheep; Valine | 2004 |
High prevalence of V37I genetic variant in the connexin-26 (GJB2) gene among non-syndromic hearing-impaired and control Thai individuals.
Topics: Adolescent; Amino Acid Substitution; Asian People; Child; Child, Preschool; Connexin 26; Connexins; Female; Hearing Loss, Sensorineural; Humans; Infant; Isoleucine; Male; Mutation, Missense; Prevalence; Thailand; Valine | 2004 |
Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase.
Topics: Amino Acid Sequence; Animals; Arginine Kinase; Catalysis; Creatine Kinase; Creatinine; Enzyme Activation; Enzyme Stability; Glycine; Humans; Isoenzymes; Isoleucine; Kinetics; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Species Specificity; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity; Valine | 2004 |
Gluthatione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Codon; Cohort Studies; Family Health; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Heterozygote; Homozygote; Humans; Isoenzymes; Isoleucine; Japan; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Prostatic Neoplasms; United States; Valine | 2004 |
The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Female; Genes, erbB-2; Genetic Carrier Screening; Genetic Predisposition to Disease; Humans; Isoleucine; Middle Aged; Polymerase Chain Reaction; Proto-Oncogene Mas; Risk Factors; Valine | 2005 |
Mitochondrial beta-oxidation in Aspergillus nidulans.
Topics: Acyl Coenzyme A; Aspergillus nidulans; Enoyl-CoA Hydratase; Fatty Acids; Fungal Proteins; Gene Deletion; Genes, Fungal; Genes, Reporter; Green Fluorescent Proteins; Isoleucine; Lactose; Luminescent Proteins; Mitochondria; Mitochondrial Trifunctional Protein; Multienzyme Complexes; Oxidation-Reduction; Peroxisomes; Recombinant Fusion Proteins; Red Fluorescent Protein; Valine | 2004 |
Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Chromatography, Affinity; Coenzymes; Escherichia coli; Glutathione Transferase; Humans; Hydroxyprostaglandin Dehydrogenases; Isoleucine; Kinetics; Models, Molecular; Models, Structural; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NAD; Protein Binding; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Valine | 2005 |
Meteoritic C alpha-methylated alpha-amino acids and the homochirality of life: searching for a link.
Topics: Amino Acids; Isoleucine; Meteoroids; Methylation; Oligopeptides; Stereoisomerism; Valine; X-Ray Diffraction | 2004 |
Allele frequencies of hemojuvelin gene (HJV) I222N and G320V missense mutations in white and African American subjects from the general Alabama population.
Topics: Adolescent; Adult; Alabama; Alleles; Amino Acid Substitution; Asparagine; Black or African American; Female; Gene Frequency; Genetics, Population; Glycine; GPI-Linked Proteins; Hemochromatosis Protein; Humans; Isoleucine; Male; Membrane Proteins; Mutation, Missense; Valine; White People | 2004 |
The correlation between monocyte chemoattractant protein-1 and the arthritis of systemic lupus erythematosus among Chinese.
Topics: Adolescent; Adult; Aged; Arthritis; Asian People; Case-Control Studies; Chemokine CCL2; Chemokine CXCL12; Chemokines; Chemokines, CXC; Female; Gene Frequency; Genotype; Guanine; Humans; Isoleucine; Lupus Erythematosus, Systemic; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Receptors, CCR2; Receptors, Chemokine; Valine | 2005 |
T280M and V249I polymorphisms of fractalkine receptor CX3CR1 and ischemic cerebrovascular disease.
Topics: Case-Control Studies; Cerebrovascular Disorders; Confidence Intervals; CX3C Chemokine Receptor 1; Female; Gene Frequency; Genotype; Humans; Isoleucine; Male; Membrane Proteins; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Threonine; Valine | 2005 |
A mathematical model for the branched chain amino acid biosynthetic pathways of Escherichia coli K12.
Topics: Acetolactate Synthase; Allosteric Regulation; Amino Acids, Branched-Chain; Escherichia coli K12; Isoenzymes; Isoleucine; Mathematics; Models, Theoretical; Threonine Dehydratase; Valine | 2005 |
The effects of amino acid replacements of glycine 20 on conformational stability and catalysis of staphylococcal nuclease.
Topics: Alanine; Amino Acid Substitution; Calcium; Catalysis; Circular Dichroism; Enzyme Stability; Glycine; Isoleucine; Kinetics; Micrococcal Nuclease; Models, Molecular; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Substrate Specificity; Urea; Valine | 2004 |
Effects of branched-chain amino acids on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Topics: Amino Acids, Branched-Chain; Animals; Antibodies, Monoclonal; Cell Proliferation; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hepatocytes; Isoleucine; Leucine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Models, Biological; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Transforming Growth Factor alpha; Type C Phospholipases; Valine | 2005 |
One pot conjugation of the polypeptides directed by phosphorus oxychloride.
Topics: Benzylamines; Isoleucine; Menthol; Molecular Structure; Peptides; Phenylalanine; Phosphorus Compounds; Spectrometry, Mass, Electrospray Ionization; Valine | 2005 |
The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana.
Topics: Amino Acids, Branched-Chain; Aminobutyrates; Arabidopsis; Arabidopsis Proteins; Butyrates; Deamination; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucuronidase; Hemiterpenes; Isoleucine; Keto Acids; Kinetics; Leucine; Methionine; Mitochondrial Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seedlings; Substrate Specificity; Transaminases; Transcription, Genetic; Valine | 2005 |
Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.
Topics: Alanine; Amino Acid Substitution; ATP-Binding Cassette Transporters; Carrier Proteins; Computer Simulation; Crystallization; Crystallography, X-Ray; Escherichia coli Proteins; Isoleucine; Leucine; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thermodynamics; Valine | 2005 |
A bias in genotyping the ERBB2 (HER2) Ile655Val variant.
Topics: Breast Neoplasms; Genetic Variation; Genotype; Humans; Isoleucine; Polymorphism, Single Nucleotide; Receptor, ErbB-2; Valine | 2005 |
Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats.
Topics: Animals; Antioxidants; Brain; Catalase; Cerebral Cortex; Chromans; Disease Models, Animal; Enzyme Inhibitors; Fluoresceins; Free Radicals; Glutathione; Glutathione Peroxidase; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valine | 2005 |
Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Anthracenes; Binding Sites; Biotinylation; Crystallography, X-Ray; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Glutathione; Humans; Imidazoles; Inhibitory Concentration 50; Isoleucine; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 10; Models, Biological; Models, Chemical; Models, Molecular; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Point Mutation; Protein Binding; Protein Folding; Pyrimidines; Valine | 2005 |
Bacillus subtilis ilvB operon: an intersection of global regulons.
Topics: Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Isoleucine; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Regulon; Repressor Proteins; Transcription, Genetic; Valine | 2005 |
Elaborate transcription regulation of the Bacillus subtilis ilv-leu operon involved in the biosynthesis of branched-chain amino acids through global regulators of CcpA, CodY and TnrA.
Topics: Amino Acids, Branched-Chain; Bacillus subtilis; Bacterial Proteins; Base Sequence; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Isoleucine; Leucine; Molecular Sequence Data; Nitrogen; Operon; Repressor Proteins; Response Elements; Transcription Factors; Transcription, Genetic; Valine | 2005 |
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Atrial Fibrillation; Cell Line; Conserved Sequence; COS Cells; DNA; DNA Mutational Analysis; Electrophysiology; Family Health; Female; Heart Atria; Humans; Isoleucine; Male; Microscopy, Confocal; Middle Aged; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Transfection; Valine | 2005 |
Genetic studies of A2M and BACE1 genes in Chinese Han Alzheimer's disease patients.
Topics: Adult; Aged; Aged, 80 and over; alpha-Macroglobulins; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoproteins E; Asian People; Aspartic Acid Endopeptidases; Chi-Square Distribution; China; DNA Mutational Analysis; Endopeptidases; Female; Gene Frequency; Genotype; Humans; Isoleucine; Male; Meta-Analysis as Topic; Middle Aged; Polymorphism, Genetic; Valine | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
Reply: a bias in genotyping of the ERBB2 (HER2) Ile655Val variant.
Topics: Breast Neoplasms; Genetic Variation; Genotype; Humans; Isoleucine; Polymorphism, Single Nucleotide; Receptor, ErbB-2; Valine | 2005 |
Biphasic kinetics of the colchicine-tubulin interaction: role of amino acids surrounding the A ring of bound colchicine molecule.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Brain Chemistry; Cattle; Colchicine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Kinetics; Leucine; Molecular Sequence Data; Peptide Fragments; Protein Interaction Mapping; Protein Isoforms; Tubulin; Valine | 2005 |
Effects of the sequence and size of non-polar residues on self-assembly of amphiphilic peptides.
Topics: Alanine; Amino Acid Motifs; Amyloid; Benzothiazoles; Circular Dichroism; Congo Red; Gene Library; Glycine; Hydrogel, Polyethylene Glycol Dimethacrylate; Isoleucine; Leucine; Macromolecular Substances; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Models, Molecular; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Temperature; Thiazoles; Ultraviolet Rays; Valine; X-Ray Diffraction | 2005 |
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine | 2005 |
Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE epsilon4 allele.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Carrier Proteins; Cholesterol Ester Transfer Proteins; Confidence Intervals; DNA Mutational Analysis; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycoproteins; Humans; Isoleucine; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Retrospective Studies; Risk Factors; Spain; Valine | 2006 |
A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.
Topics: Algorithms; Animals; Biophysical Phenomena; Biophysics; Calorimetry, Differential Scanning; Cluster Analysis; Databases, Protein; Escherichia coli; Evolution, Molecular; Isoleucine; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Denaturation; Protein Folding; Thermodynamics; Thioredoxins; Valine | 2005 |
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis.
Topics: Acyltransferases; Amino Acids; Bacterial Proteins; Catalysis; Chlorine; Enzymes; Heme; Indenes; Iron; Isoleucine; Pseudomonas syringae; Valine | 2005 |
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.
Topics: Amines; Amino Acid Sequence; Anticonvulsants; Binding Sites; Crystallization; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Cytosol; Dithiothreitol; Gabapentin; gamma-Aminobutyric Acid; Isoenzymes; Isoleucine; Lysine; Mitochondria; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Sequence Homology, Amino Acid; Substrate Specificity; Transaminases; Valine | 2005 |
A new protein substitute for adolescents and adults with maple syrup urine disease (MSUD).
Topics: Adolescent; Adult; Amino Acids; Body Weight; Diet; Diet, Protein-Restricted; Dietary Proteins; Female; Food, Formulated; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Valine | 2005 |
Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Disease Progression; Female; Genotype; Glutathione Transferase; Hemochromatosis; Hepatitis C, Chronic; Humans; Isoleucine; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Prognosis; Valine | 2005 |
Association study of Glutathione S-transferase P1 (GSTP1) with asthma and bronchial hyper-responsiveness in two German pediatric populations.
Topics: Adolescent; Alanine; Asthma; Bronchial Hyperreactivity; Child; Child, Preschool; Dermatitis, Atopic; Follow-Up Studies; Forced Expiratory Volume; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Glutathione S-Transferase pi; Humans; Isoleucine; Polymorphism, Genetic; Respiratory Function Tests; Rhinitis, Allergic, Perennial; Valine | 2005 |
Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).
Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Blotting, Western; DNA, Complementary; Dose-Response Relationship, Drug; Fructose; Glucose; Glucose Transport Proteins, Facilitative; Hexoses; Humans; Immunohistochemistry; Isoleucine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Transport; RNA, Complementary; Sequence Homology, Amino Acid; Substrate Specificity; Valine; Xenopus; Xenopus laevis | 2005 |
[Neonatal leucinosis with favourable course. Therapeutic problems].
Topics: Acidosis; Child, Preschool; Diagnosis, Differential; Follow-Up Studies; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Neurologic Examination; Peritoneal Dialysis; Seizures; Valine | 1977 |
Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Animals; Cell Membrane; Cloning, Molecular; Dimerization; Electrophysiology; Glycine; Immunoprecipitation; Isoleucine; Membrane Glycoproteins; Membrane Potentials; Mice; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Oocytes; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium; Protein Binding; Protein Structure, Tertiary; Rats; RNA, Complementary; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Tryptophan; Valine; Xenopus | 2005 |
An 11-day-old boy with lethargy, poor feeding, vomiting. Maple syrup urine disease.
Topics: Amino Acids; Diagnosis, Differential; Feeding and Eating Disorders; Humans; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Sleep Stages; Valine; Vomiting | 2005 |
Activator Gcn4p and Cyc8p/Tup1p are interdependent for promoter occupancy at ARG1 in vivo.
Topics: Argininosuccinate Lyase; Argininosuccinate Synthase; Basic-Leucine Zipper Transcription Factors; Chromatin Immunoprecipitation; DNA Polymerase II; DNA-Binding Proteins; Drug Resistance; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Isoleucine; Nuclear Proteins; Promoter Regions, Genetic; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Valine | 2005 |
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.
Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine | 2005 |
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.
Topics: Alleles; Aurora Kinase A; Aurora Kinases; Case-Control Studies; Disease Progression; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Isoleucine; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Risk; Stomach Neoplasms; Valine | 2006 |
Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles.
Topics: Adsorption; Aspartic Acid; Bile Acids and Salts; Caprylates; Colipases; Diglycerides; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Isoleucine; Kinetics; Leucine; Lipase; Lysine; Micelles; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pancreas; Phosphatidylcholines; Phospholipids; Pressure; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Secondary; Proteins; Time Factors; Triglycerides; Triolein; Valine | 2006 |
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
Topics: Arginine; Brain; DNA Mutational Analysis; Glycine; Humans; Iron; Isoleucine; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor); Tremor; Valine | 2006 |
Structural definition of the H-2Kd peptide-binding motif.
Topics: Alleles; Amino Acid Motifs; Animals; Antigen Presentation; Binding Sites; Crystallography, X-Ray; Electrons; Electrophoresis, Polyacrylamide Gel; Epitopes; H-2 Antigens; HLA Antigens; Hydrogen Bonding; Influenza A virus; Isoleucine; Kinetics; Leucine; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Models, Chemical; Models, Molecular; Nucleoproteins; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Solvents; Surface Properties; Valine; X-Ray Diffraction | 2006 |
A novel Val734Ile variant in the ABCC9 gene associated with myocardial infarction.
Topics: Alleles; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Conserved Sequence; Exons; Female; Genetic Variation; Genotype; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Myocardial Infarction; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sequence Alignment; Sulfonylurea Receptors; Valine | 2006 |
Transthyretin V122I in African Americans with congestive heart failure.
Topics: Black or African American; Gene Frequency; Heart Failure; Heterozygote; Humans; Isoleucine; Mutation; Prealbumin; Valine | 2006 |
Expanding the mutational spectrum in TGFBI-linked corneal dystrophies: Identification of a novel and unusual mutation (Val113Ile) in a family with granular dystrophy.
Topics: Adenine; Adult; Base Sequence; Corneal Dystrophies, Hereditary; Corneal Opacity; Corneal Stroma; Extracellular Matrix Proteins; Female; Guanine; Heterozygote; Humans; Isoleucine; Mutation, Missense; Transforming Growth Factor beta; Valine | 2006 |
Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Aspartic Acid; CHO Cells; Cricetinae; Humans; Isoleucine; Isoxazoles; Ligands; Lysine; Molecular Sequence Data; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, beta-1; Terbutaline; Valine | 2006 |
Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase.
Topics: Amino Acid Sequence; Binding Sites; Histidine; Isoleucine; Isoleucine-tRNA Ligase; Leucine-tRNA Ligase; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Tertiary; RNA Editing; Sequence Homology, Amino Acid; Structural Homology, Protein; Thermus thermophilus; Tryptophan; Valine; Valine-tRNA Ligase | 2006 |
[Acrodermatitis enteropathica-like syndrome secondary to branched-chain amino acid deficiency during treatment of maple syrup urine disease].
Topics: Acrodermatitis; Female; Humans; Infant; Isoleucine; Maple Syrup Urine Disease; Syndrome; Valine | 2006 |
Characterization of the stomatin domain involved in homo-oligomerization and lipid raft association.
Topics: Amino Acid Sequence; Amino Acids; Cell Line, Tumor; Clone Cells; Detergents; HeLa Cells; Humans; Isoleucine; Membrane Microdomains; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Protein Structure, Tertiary; Valine | 2006 |
Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alanine; alpha-Macroglobulins; Alzheimer Disease; Cathepsin D; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Isoleucine; Male; Odds Ratio; Polymorphism, Genetic; Risk; Valine | 2006 |
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).
Topics: Adaptor Proteins, Signal Transducing; Aged; alpha-Synuclein; Amyotrophic Lateral Sclerosis; Brain; DNA Mutational Analysis; Endosomal Sorting Complexes Required for Transport; Glial Fibrillary Acidic Protein; Glutamine; Histidine; Humans; Immunohistochemistry; Isoleucine; Male; Mutation; Nerve Tissue Proteins; Neurofilament Proteins; Phenotype; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequestosome-1 Protein; Spinal Cord; tau Proteins; Ubiquitin; Valine | 2006 |
Autopsy-proven Creutzfeldt-Jakob disease with a codon 180 mutation showing dissociation between diffusion-weighted magnetic resonance imaging and single-photon emission computed tomography findings: Is this a suggestive finding in long survival?
Topics: Aged; Autopsy; Cerebral Cortex; Creutzfeldt-Jakob Syndrome; Diffusion Magnetic Resonance Imaging; Female; Humans; Isoleucine; Methionine; Mutation; Prions; Tomography, Emission-Computed, Single-Photon; Valine | 2006 |
Dietary branched-chain amino acid valine, isoleucine and leucine requirements of fingerling Indian major carp, Cirrhinus mrigala (Hamilton).
Topics: Amino Acids, Branched-Chain; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Carps; Diet; Isoleucine; Leucine; Nutritional Requirements; Valine; Weight Gain | 2006 |
The functional genetic variant Ile646Val located in the kinase binding domain of the A-kinase anchoring protein 10 is associated with familial breast cancer.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Base Sequence; Breast Neoplasms; Cohort Studies; DNA Primers; Genetic Predisposition to Disease; Genetic Variation; Humans; Isoleucine; Risk Factors; Valine | 2007 |
Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase.
Topics: Acetate-CoA Ligase; Acetates; Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Coenzyme A; Isoleucine; Kinetics; Methanobacteriaceae; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Saccharomyces cerevisiae; Salmonella enterica; Sequence Alignment; Substrate Specificity; Threonine; Tryptophan; Valine | 2006 |
V180I mutation of the prion protein gene associated with atypical PrPSc glycosylation.
Topics: Animals; Blotting, Western; Brain; CHO Cells; Cricetinae; Cricetulus; Glycosylation; Humans; Isoleucine; Mutagenesis; Mutation; Protein Kinases; PrPSc Proteins; Transfection; Valine | 2006 |
Non-responsiveness to gefitinib in a patient with lung adenocarcinoma having rare EGFR mutations S768I and V769L.
Topics: Adenocarcinoma; DNA, Neoplasm; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Isoleucine; Leucine; Lung Neoplasms; Male; Middle Aged; Mutation; Quinazolines; Serine; Valine | 2006 |
Both experimental and theoretical investigations of solid-state 17O NMR for L-valine and L-isoleucine.
Topics: Isoleucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxygen Isotopes; Valine | 2006 |
Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.
Topics: Brugada Syndrome; Genetic Carrier Screening; Humans; Isoleucine; Leucine; Muscle Proteins; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Pedigree; Phenotype; Proline; Sodium Channels; Valine | 2006 |
Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Glutamine; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Protein Structure, Secondary; Valine; Xanthine | 2006 |
L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.
Topics: Alanine; Corynebacterium glutamicum; Fermentation; Isoleucine; Lysine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Valine | 2007 |
Characterization of a familial case with primary erythromelalgia from Taiwan.
Topics: Adult; Chromosomes, Human, Pair 2; DNA Mutational Analysis; Erythromelalgia; Family Health; Genetic Linkage; Humans; Isoleucine; Male; NAV1.7 Voltage-Gated Sodium Channel; Nerve Fibers; Pedigree; Proteins; Sodium Channels; Taiwan; Valine | 2007 |
Biosynthesis of hyperforin and adhyperforin from amino acid precursors in shoot cultures of Hypericum perforatum.
Topics: Amino Acids; Bridged Bicyclo Compounds; Carbon Isotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Hypericum; Isoleucine; Leucine; Molecular Structure; Phloroglucinol; Plant Shoots; Tandem Mass Spectrometry; Terpenes; Threonine; Valine | 2007 |
Localization and expression of substance P in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Gene Expression; Glial Fibrillary Acidic Protein; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Mice, Transgenic; Mutation; Substance P; Valine | 2007 |
Trigger finger as an initial manifestation of familial amyloid polyneuropathy in a patient with Ile107Val TTR.
Topics: Age of Onset; Aged; Amino Acid Substitution; Amyloid Neuropathies, Familial; Carpal Tunnel Syndrome; Female; Humans; Isoleucine; Male; Middle Aged; Prealbumin; Trigger Finger Disorder; Valine | 2007 |
Effects of bioactive peptides isoleucine-proline-proline (IPP), valine-proline-proline (VPP) and leucine-lysine-proline (LKP) on gene expression of osteoblasts differentiated from human mesenchymal stem cells.
Topics: Amino Acids, Branched-Chain; Bone Marrow Cells; Cell Differentiation; Female; Gene Expression; Humans; Isoleucine; Lysine; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Proline; Valine | 2007 |
The V118I mutation as a marker of advanced HIV infection and disease progression.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Disease Progression; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Logistic Models; Male; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Risk Assessment; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Failure; Valine | 2007 |
Patients with a sodium channel alpha 1 gene mutation show wide phenotypic variation.
Topics: Adult; Child; DNA Mutational Analysis; Epilepsy; Female; Genetic Predisposition to Disease; Humans; Isoleucine; Male; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Pedigree; Phenotype; Sodium Channels; Valine | 2007 |
The conserved isoleucine-valine-phenylalanine motif couples activation state and endocytic functions of beta-arrestins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arrestins; beta-Arrestins; Chlorocebus aethiops; Conserved Sequence; COS Cells; HeLa Cells; Humans; Isoleucine; Molecular Sequence Data; Phenylalanine; Receptors, G-Protein-Coupled; Sequence Homology, Amino Acid; Valine | 2007 |
Purification, crystallization and preliminary X-ray crystallographic analysis of branched-chain aminotransferase from Deinococcus radiodurans.
Topics: Bacterial Proteins; Crystallization; Crystallography, X-Ray; Deinococcus; Isoleucine; Leucine; Transaminases; Valine | 2007 |
Erythrocyte glutathione peroxidase activity and plasma selenium concentration are reduced in maple syrup urine disease patients during treatment.
Topics: Catalase; Child; Child, Preschool; Erythrocytes; Female; Glutathione Peroxidase; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Selenium; Superoxide Dismutase; Valine | 2007 |
A single acyl-CoA dehydrogenase is required for catabolism of isoleucine, valine and short-chain fatty acids in Aspergillus nidulans.
Topics: Acyl Coenzyme A; Acyl-CoA Dehydrogenases; Aspergillus nidulans; Erucic Acids; Fatty Acids; Fungal Proteins; Gas Chromatography-Mass Spectrometry; Genetic Complementation Test; Isoleucine; Molecular Structure; Mutation; Myristic Acid; Oleic Acid; Oxidation-Reduction; Transcription, Genetic; Valine | 2008 |
Steric interactions stabilize the signaling state of the LOV2 domain of phototropin 1.
Topics: Arginine; Circular Dichroism; Cryptochromes; Cysteine; Directed Molecular Evolution; Electric Conductivity; Escherichia coli; Flavoproteins; Isoleucine; Light; Lysine; Mutagenesis, Site-Directed; Oxygen; Photochemistry; Plant Proteins; Protein Structure, Tertiary; Signal Transduction; Spectrometry, Fluorescence; Stereoisomerism; Valine | 2007 |
[Compliance of the diet restricted with leucine, isoleucine and valine in maple syrup urine disease (MSUD) children].
Topics: Adolescent; Calcium; Child; Child, Preschool; Copper; Diet Records; Dietary Proteins; Energy Intake; Female; Humans; Infant; Iron Deficiencies; Isoleucine; Leucine; Longitudinal Studies; Male; Maple Syrup Urine Disease; Nutritional Requirements; Patient Compliance; Valine; Vitamins; Zinc | 2007 |
Human tryptophanyl-tRNA synthetase is switched to a tRNA-dependent mode for tryptophan activation by mutations at V85 and I311.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Humans; Hydrophobic and Hydrophilic Interactions; Isoleucine; Molecular Sequence Data; Mutation; Protein Binding; RNA, Transfer, Trp; Schiff Bases; Sequence Alignment; Tryptophan; Tryptophan-tRNA Ligase; Valine | 2007 |
Probing supramolecular structure from measurement of methyl (1)H-(13)C residual dipolar couplings.
Topics: Biochemistry; Carbon; Crystallography, X-Ray; Hydrogen; Isoleucine; Leucine; Models, Molecular; Molecular Weight; Proteasome Endopeptidase Complex; Protons; Spectrophotometry; Valine | 2007 |
Multiplex PCR detection of GSTM1, GSTT1, and GSTP1 gene variants: simultaneously detecting GSTM1 and GSTT1 gene copy number and the allelic status of the GSTP1 Ile105Val genetic variant.
Topics: Alleles; Female; Gene Deletion; Gene Dosage; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Male; Mutation; Polymerase Chain Reaction; Valine | 2007 |
Distal Val346Ile mutation in inducible NO synthase promotes substrate-dependent NO confinement.
Topics: Amino Acid Substitution; Binding Sites; Hydrogen Bonding; Isoleucine; Kinetics; Models, Molecular; Mutation; Nitric Oxide; Nitric Oxide Synthase Type II; Substrate Specificity; Valine | 2007 |
Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions.
Topics: Adult; Amino Acids, Branched-Chain; Female; Flavoring Agents; Food, Formulated; Humans; Isoleucine; Leucine; Male; Pharmaceutical Solutions; Sweetening Agents; Taste; Taste Threshold; Valine | 2007 |
The orexin 1 receptor (HCRTR1) gene as a susceptibility gene contributing to polydipsia-hyponatremia in schizophrenia.
Topics: Adult; Age of Onset; Aged; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genotype; Humans; Hyponatremia; Isoleucine; Male; Middle Aged; Orexin Receptors; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Schizophrenia; Thirst; Valine | 2007 |
First case of V281+I172N/V281L CYP21A2 genotype associated with congenital adrenal hyperplasia form. A case report from South Italy.
Topics: Adrenal Hyperplasia, Congenital; Adult; Female; Genotype; Humans; Isoleucine; Italy; Male; Polymorphism, Genetic; Siblings; Steroid 21-Hydroxylase; Valine | 2007 |
Caught in the Act: the 1.5 A resolution crystal structures of the HIV-1 protease and the I54V mutant reveal a tetrahedral reaction intermediate.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; HIV Protease; HIV-1; Hydrogen Bonding; Isoleucine; Ligands; Models, Molecular; Mutation; Protein Structure, Quaternary; Valine | 2007 |
Critical role of Val-304 in conformational transitions that allow Ca2+ occlusion and phosphoenzyme turnover in the Ca2+ transport ATPase.
Topics: Adenosine Triphosphatases; Animals; Calcium; Chlorocebus aethiops; COS Cells; Isoleucine; Lysine; Models, Biological; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Threonine; Valine | 2008 |
A case-control study of the HER2 Ile655Val polymorphism and risk of breast cancer in Taiwan.
Topics: Adult; Age Factors; Breast Neoplasms; Case-Control Studies; Female; Genes, erbB-2; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Middle Aged; Neoplasm Staging; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reference Values; Risk Factors; Taiwan; Valine | 2008 |
Nitrogen balance index and specific dynamic action in rats receiving amino acid mixtures low in isoleucine, methionine or valine.
Topics: Amino Acids; Animals; Isoleucine; Methionine; Nitrogen; Rats; Valine | 1948 |
Effect of folic acid, 4-amino folic acids and related substances on growth of chick embryo.
Topics: Folic Acid; Growth; Humans; Isoleucine; Leucine; Valine; Vitamin B Complex; Vitamins | 1949 |
Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Substitution; Cell Line; Child; Erythromelalgia; Humans; Isoleucine; Kinetics; NAV1.7 Voltage-Gated Sodium Channel; Pain; Patch-Clamp Techniques; Sodium Channels; Valine | 2008 |
Targeting of mitochondrial Saccharomyces cerevisiae Ilv5p to the cytosol and its effect on vicinal diketone formation in brewing.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Beer; Cytosol; Enzyme Stability; Fermentation; Genetic Complementation Test; Green Fluorescent Proteins; Isoleucine; Ketones; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Protein Transport; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Sequence Deletion; Valine | 2008 |
SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder.
Topics: Adolescent; Adult; Asperger Syndrome; Autistic Disorder; Base Sequence; DNA Mutational Analysis; Female; Genotype; Humans; Isoleucine; Male; Molecular Sequence Data; Obsessive-Compulsive Disorder; Serotonin Plasma Membrane Transport Proteins; Valine | 2008 |
Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate.
Topics: Cell Division; Gene Expression Regulation, Archaeal; Hydrogen; Isoleucine; Leucine; Methanococcus; Phosphates; RNA, Messenger; RNA, Ribosomal; RNA, Transfer, Leu; Valine | 2008 |
Experimental evidence for three pheromone races of the scarab beetle Phyllophaga anxia (LeConte).
Topics: Animals; Behavior, Animal; Coleoptera; Exocrine Glands; Female; Isoleucine; Male; Massachusetts; New York; Pheromones; Valine | 2008 |
Influence of L-isoleucine and pantothenate auxotrophy for L-valine formation in Corynebacterium glutamicum revisited by metabolome analyses.
Topics: Biomass; Biotechnology; Chromatography, Liquid; Corynebacterium glutamicum; Cytoplasm; Glycolysis; Isoleucine; Mass Spectrometry; Metabolism; Models, Chemical; Pantothenic Acid; Pyruvates; Time Factors; Tricarboxylic Acids; Valine | 2008 |
Auxotrophy in natural isolate: minimal requirements for growth of the Antarctic psychrotrophic bacterium Pseudomonas syringae Lz4W.
Topics: Acetolactate Synthase; Antarctic Regions; Bacterial Proteins; Biosynthetic Pathways; Cold Temperature; Culture Media; Glucose; Isoleucine; Osmolar Concentration; Pseudomonas syringae; Succinic Acid; Valine | 2008 |
Heart transplantation for homozygous familial transthyretin (TTR) V122I cardiac amyloidosis.
Topics: Amino Acid Substitution; Amyloidosis, Familial; Heart Transplantation; Homozygote; Humans; Isoleucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Prealbumin; Treatment Outcome; Valine | 2008 |
Chromogranin B and Secretogranin II in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations and in Alzheimer patients.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain; Chromogranin B; Gene Expression; Glial Fibrillary Acidic Protein; Isoleucine; Leucine; Methionine; Mice; Mice, Transgenic; Point Mutation; Secretogranin II; Substance P; Valine | 2008 |
Early diagnosis of maple syrup urine disease using polymerase chain reaction-based mutation detection.
Topics: Alleles; Chromatography, Thin Layer; Diagnosis, Differential; DNA; Gene Deletion; Humans; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Mutation; Polymerase Chain Reaction; Protein Kinases; Reproducibility of Results; Time Factors; Valine | 2008 |
Isoleucine and valine supplementation of a low-protein corn-wheat-soybean meal-based diet for piglets: growth performance and nitrogen balance.
Topics: Animal Feed; Animals; Diet, Protein-Restricted; Dietary Supplements; Eating; Isoleucine; Male; Nitrogen; Random Allocation; Swine; Valine | 2008 |
CYP1A1 Ile462Val and GSTT1 modify the effect of cord blood cotinine on neurodevelopment at 2 years of age.
Topics: Adult; Child Development; Child, Preschool; Cotinine; Cytochrome P-450 CYP1A1; Female; Fetal Blood; Glutathione Transferase; Humans; Infant, Newborn; Isoleucine; Language; Linear Models; Male; Motor Activity; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Taiwan; Valine | 2008 |
GC-MS with ethyl chloroformate derivatization for comprehensive analysis of metabolites in serum and its application to human uremia.
Topics: Formic Acid Esters; Gas Chromatography-Mass Spectrometry; Humans; Isoleucine; Leucine; Linoleic Acid; Myristic Acid; Reference Standards; Reproducibility of Results; Uremia; Valine | 2008 |
Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease.
Topics: Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Multiple, Viral; HIV Protease; HIV Protease Inhibitors; Isoleucine; Kinetics; Models, Molecular; Mutation; Pyrrolidines; Valine | 2008 |
Auxotrophy accounts for nodulation defect of most Sinorhizobium meliloti mutants in the branched-chain amino acid biosynthesis pathway.
Topics: Amino Acids, Branched-Chain; Bacterial Proteins; Biosynthetic Pathways; Gene Expression Profiling; Gene Expression Regulation, Plant; Host-Pathogen Interactions; Isoleucine; Leucine; Medicago sativa; Mutation; N-Acetylglucosaminyltransferases; Plant Root Nodulation; Reverse Transcriptase Polymerase Chain Reaction; Root Nodules, Plant; Sinorhizobium meliloti; Symbiosis; Valine | 2008 |
Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy.
Topics: Adult; Alanine; Amino Acids; Biomarkers; Brain Abscess; Female; Humans; Image Processing, Computer-Assisted; Isoleucine; Lactic Acid; Leucine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Sensitivity and Specificity; Valine; Young Adult | 2008 |
HER-2/neu Ile655Val polymorphism and the risk of breast cancer.
Topics: Breast Neoplasms; Case-Control Studies; Female; Genes, erbB-2; Genetic Predisposition to Disease; Humans; Isoleucine; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Mas; Risk Factors; Valine | 2008 |
Allosteric regulation of Bacillus subtilis threonine deaminase, a biosynthetic threonine deaminase with a single regulatory domain.
Topics: Allosteric Regulation; Aminobutyrates; Bacillus subtilis; Bacterial Proteins; Binding Sites; Isoleucine; Kinetics; Mutation; Protein Binding; Protein Structure, Secondary; Threonine; Threonine Dehydratase; Valine | 2008 |
Chromatography of amino acids on starch columns; separation of phenylalanine, leucine, isoleucine, methionine, tyrosine, and valine.
Topics: Amino Acids; Chromatography; Isoleucine; Leucine; Methionine; Phenylalanine; Starch; Tyrosine; Valine | 1948 |
Biosynthetic and environmental effects on the stable carbon isotopic compositions of anteiso- (3-methyl) and iso- (2-methyl) alkanes in tobacco leaves.
Topics: Alkanes; Carbon; Carbon Isotopes; Chloroplasts; Cytosol; Hydrocarbons; Isoleucine; Light; Nicotiana; Plant Leaves; Temperature; Valine; Water | 2008 |
Point mutations in the barley HvHAK1 potassium transporter lead to improved K+-nutrition and enhanced resistance to salt stress.
Topics: Amino Acid Substitution; Arginine; Cation Transport Proteins; Cysteine; Ion Transport; Isoleucine; Osmotic Pressure; Plant Proteins; Point Mutation; Potassium; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Sodium; Sodium Chloride; Valine | 2008 |
A novel dominant mutation of the Nav1.4 alpha-subunit domain I leading to sodium channel myotonia.
Topics: Cell Line; DNA Mutational Analysis; Family Health; Female; Humans; Isoleucine; Membrane Potentials; Mutation; Myotonia; NAV1.4 Voltage-Gated Sodium Channel; Protein Subunits; Sodium Channels; Transfection; Valine | 2008 |
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum.
Topics: Acetolactate Synthase; Bacterial Proteins; Butyrates; Corynebacterium glutamicum; Enzyme Inhibitors; Gene Expression Profiling; Isoleucine; Kinetics; Leucine; Lysine; Pyruvic Acid; Sequence Deletion; Valine | 2009 |
Terahertz spectra and normal mode analysis of the crystalline VA class dipeptide nanotubes.
Topics: Alanine; Crystallization; Dipeptides; Isoleucine; Models, Molecular; Nanotubes, Peptide; Spectrum Analysis; Thermodynamics; Valine | 2008 |
Two new hemoglobin variants: Hb Sinai-Greenspring [beta34(B16)Val-->Ile, GTC > ATC] and Hb Sinai-Bel Air [beta53(D4)Ala-->Asp, GCT > GAT].
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Base Sequence; beta-Globins; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Isoleucine; Male; Molecular Sequence Data; Mutation; Valine | 2008 |
Development of micellar electro kinetic chromatography for the separation and quantitation of L-valine, L-leucine, L-isoleucin and L-phenylalanine in human plasma and comparison with HPLC.
Topics: Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Humans; Isoleucine; Leucine; Maple Syrup Urine Disease; Phenylalanine; Phenylketonurias; Plasma; Reproducibility of Results; Valine | 2007 |
Amino acids levels and lipid peroxidation in maple syrup urine disease patients.
Topics: Adult; Amino Acids; Antioxidants; Humans; Hydroxy Acids; Isoleucine; Keto Acids; Leucine; Lipid Peroxidation; Maple Syrup Urine Disease; Methionine; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Tryptophan; Valine | 2009 |
Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation.
Topics: Bacterial Proteins; Cloning, Molecular; Corynebacterium glutamicum; Culture Media; Genetic Engineering; Hydro-Lyases; Isoleucine; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Threonine Dehydratase; Transaminases; Valine | 2009 |
Ileal digestibility and endogenous flow of minerals and amino acids: responses to dietary phytic acid in piglets.
Topics: Amino Acids; Animal Feed; Animals; Calcium; Digestion; Ileum; Isoleucine; Leucine; Magnesium; Male; Minerals; Phosphorus; Phytic Acid; Potassium; Random Allocation; Sodium; Swine; Valine | 2009 |
Stabilization of neutral NH2-R-COOH form of the antihypertensive peptides L-Valyl-L-Prolyl-L-Proline and L-Isoleucyl-L-Prolyl-L-Proline.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chromatography, High Pressure Liquid; Isoleucine; Models, Molecular; Normal Distribution; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Proline; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Tandem Mass Spectrometry; Valine | 2009 |
Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.
Topics: ADAM Proteins; ADAM10 Protein; Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Behavior, Animal; Disease Models, Animal; Glutamic Acid; Humans; Isoleucine; Maze Learning; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reaction Time; Swimming; Valine | 2009 |
Relationship between GSTP1 Ile(105)Val polymorphism and docetaxel-induced peripheral neuropathy: clinical evidence of a role of oxidative stress in taxane toxicity.
Topics: Aged; Antineoplastic Agents, Phytogenic; Docetaxel; Female; Glutathione Transferase; Humans; Isoleucine; Male; Middle Aged; Oxidative Stress; Peripheral Nervous System Diseases; Polymorphism, Genetic; Taxoids; Valine | 2009 |
Methyl-detected 'out-and-back' NMR experiments for simultaneous assignments of Alabeta and Ilegamma2 methyl groups in large proteins.
Topics: Alanine; Algorithms; Carbon Isotopes; Computer Simulation; Escherichia coli; Isoleucine; Malate Synthase; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteins; Pyruvic Acid; Valine | 2009 |
Polymorphism Val103Ile of the melanocortin-4 receptor gene in the Serbian population.
Topics: Adult; Amino Acid Substitution; Female; Heterozygote; Homozygote; Humans; Isoleucine; Male; Obesity; Polymorphism, Single Nucleotide; Receptor, Melanocortin, Type 4; Serbia; Valine | 2010 |
Selective backbone labelling of ILV methyl labelled proteins.
Topics: Carbon Isotopes; Cyclophilins; Isoleucine; Isotope Labeling; Leucine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteins; Valine | 2009 |
Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men.
Topics: Adipose Tissue; Adiposity; Adult; Age Factors; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Down-Regulation; Fatty Acid Synthase, Type I; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Time Factors; Valine; Waist-Hip Ratio; Weight Gain | 2009 |
TAQIB and I405V polymorphisms of CETP are moderately associated with obesity risk in the Chinese adult population.
Topics: Adult; Amino Acid Substitution; Asian People; Case-Control Studies; Cholesterol Ester Transfer Proteins; Deoxyribonucleases, Type II Site-Specific; Female; Genetic Predisposition to Disease; Genetics, Population; Humans; Isoleucine; Male; Middle Aged; Obesity; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk; Valine | 2010 |
Polymorphisms and haplotype analysis of IL-4Ralpha Q576R and I75V in patients with penicillin allergy.
Topics: Adolescent; Arginine; Case-Control Studies; Drug Hypersensitivity; Female; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Immunoglobulin E; Interleukin-4 Receptor alpha Subunit; Isoleucine; Linkage Disequilibrium; Male; Penicillins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Shock; Urticaria; Valine; Young Adult | 2009 |
Cu(II)-catalyzed reactions in ternary [Cu(AA)(AA - H)]+ complexes (AA = Gly, Ala, Val, Leu, Ile, t-Leu, Phe).
Topics: Alanine; Amino Acids; Catalysis; Copper; Dimerization; Glycine; Isoleucine; Leucine; Ligands; Molecular Structure; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Valine | 2009 |
I405V and -629C/A polymorphisms of the cholesteryl ester transfer protein gene in patients with coronary artery disease.
Topics: Amino Acid Substitution; Anthropometry; Cholesterol Ester Transfer Proteins; Coronary Artery Disease; Gene Frequency; Genotype; Humans; Isoleucine; Middle Aged; Polymorphism, Single Nucleotide; Valine | 2009 |
Backbone and sidechain methyl Ile (delta1), Leu and Val resonance assignments of the catalytic domain of the yeast mRNA decapping enzyme, Dcp2.
Topics: Catalytic Domain; Endoribonucleases; Isoleucine; Leucine; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Valine | 2007 |
Vibrational analysis of amino acids and short peptides in hydrated media. IV. Amino acids with hydrophobic side chains: L-alanine, L-valine, and L-isoleucine.
Topics: Alanine; Amino Acids; Carbon; Deuterium Oxide; Hydrogen; Isoleucine; Leucine; Models, Theoretical; Molecular Conformation; Peptides; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Valine; Water | 2009 |
D-amino acids govern stationary phase cell wall remodeling in bacteria.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; Bacillus subtilis; Cell Wall; Down-Regulation; Glutamic Acid; Isoleucine; Leucine; Methionine; Oligopeptides; Peptidoglycan; Polysaccharides; Stereoisomerism; Valine; Vibrio cholerae | 2009 |
Assignment of Ile, Leu, and Val methyl correlations in supra-molecular systems: an application to aspartate transcarbamoylase.
Topics: Aspartate Carbamoyltransferase; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Reference Standards; Valine | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin.
Topics: Acetolactate Synthase; Animals; Antifungal Agents; Candida albicans; Carbon; Fungal Proteins; Isoleucine; Male; Mice; Microbial Viability; Mutation; Phenotype; Saccharomyces cerevisiae; Sirolimus; Valine; Virulence | 2010 |
HER2 codon 655 polymorphism is associated with advanced uterine cervical carcinoma.
Topics: Adult; Aged; Amino Acid Substitution; Carcinoma; Case-Control Studies; Codon; Female; Gene Frequency; Genetic Linkage; Genetic Testing; Genotype; Humans; Incidence; Isoleucine; Middle Aged; Polymorphism, Single Nucleotide; Receptor, ErbB-2; Uterine Cervical Neoplasms; Valine | 2010 |
The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.
Topics: Adult; Amino Acid Substitution; Biomarkers; Female; Genotype; Glutathione S-Transferase pi; Humans; Isoleucine; Male; Middle Aged; Phenylenediamines; Polymorphism, Single Nucleotide; Toluene 2,4-Diisocyanate; Valine; Young Adult | 2010 |
MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.
Topics: Adult; Aged; Breast Neoplasms; Colorectal Neoplasms; Diet; DNA Modification Methylases; DNA Repair Enzymes; Female; Genotype; Humans; Isoleucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Prostatic Neoplasms; Risk Factors; Tumor Suppressor Proteins; Valine | 2010 |
Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins.
Topics: Alanine; Escherichia coli Proteins; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Periplasmic Proteins; Reference Standards; Threonine; Valine | 2010 |
The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Analysis of Variance; Animals; Diet; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Isoleucine; Keto Acids; Leucine; Linear Models; Liver; Metabolism; Receptors, Somatotropin; RNA, Messenger; Somatomedins; Swine; Valine; Weaning | 2010 |
Degradation kinetics of branched-chain amino acids in subcritical water.
Topics: Amino Acids, Branched-Chain; Hot Temperature; Isoleucine; Kinetics; Leucine; Valine; Waste Management; Water | 2010 |
Topological frustration in beta alpha-repeat proteins: sequence diversity modulates the conserved folding mechanisms of alpha/beta/alpha sandwich proteins.
Topics: Amino Acid Sequence; Bacterial Proteins; Conserved Sequence; Escherichia coli Proteins; Isoleucine; Leucine; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Molecular; Molecular Sequence Data; PII Nitrogen Regulatory Proteins; Protein Folding; Protein Structure, Secondary; Repetitive Sequences, Amino Acid; Thermodynamics; Transcription Factors; Valine | 2010 |
Further studies of mutant strains of Neurospora requiring isoleucine and valine.
Topics: Amino Acids; Isoleucine; Leucine; Neurospora; Valine | 1946 |
Amino acid content of feeds; leucine, valine, isoleucine and phenylalanine.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Isoleucine; Leucine; Phenylalanine; Valine | 1947 |
Manganese superoxide dismutase (MnSOD) gene (Ala-9Val, Ile58Thr) polymorphism in patients with age-related macular degeneration (AMD).
Topics: Aged; Alanine; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoleucine; Macular Degeneration; Male; Middle Aged; Models, Genetic; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Threonine; Valine | 2010 |
Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum DeltailvA DeltapanB ilvNM13 (pECKAilvBNC).
Topics: Acetolactate Synthase; Autotrophic Processes; Bacterial Proteins; Corynebacterium glutamicum; Genetic Engineering; Hydro-Lyases; Isoleucine; Ketol-Acid Reductoisomerase; Valine | 2010 |
Globular structure of a human immunodeficiency virus-1 protease (1DIFA dimer) in an effective solvent medium by a Monte Carlo simulation.
Topics: Amino Acid Sequence; Arginine; Computer Simulation; HIV-1; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Molecular Sequence Data; Monte Carlo Method; Protein Conformation; Protein Folding; Protein Multimerization; Solvents; Static Electricity; Valine | 2010 |
Optimal methyl labeling for studies of supra-molecular systems.
Topics: Carbon Isotopes; Deuterium; Isoleucine; Leucine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine | 2010 |
Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies.
Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; Black or African American; Female; Gene Frequency; Heart Diseases; Humans; Isoleucine; Kaplan-Meier Estimate; Male; Middle Aged; Mutation; Prealbumin; Ultrasonography; Valine | 2010 |
Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder.
Topics: Alanine; Amino Acids; Case-Control Studies; Depression; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Male; Middle Aged; Polymorphism, Genetic; Sex Factors; Superoxide Dismutase; Threonine; Valine | 2010 |
Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Cell Line; Conserved Sequence; Ghrelin; Humans; Isoleucine; Models, Molecular; Protein Binding; Protein Interaction Domains and Motifs; Receptors, Gastrointestinal Hormone; Receptors, Ghrelin; Receptors, Neuropeptide; Signal Transduction; Tryptophan; Valine | 2010 |
Single amino acid alteration between valine and isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Crystallography, X-Ray; Isoleucine; Protein Structure, Tertiary; Receptors, Cell Surface; Valine | 2010 |
Lack of association between monocyte protein-1 (MCP-1) -2518 A>G chemoattractant and C-C chemokine receptor 2 (CCR2) Val64Ile polymorphisms and multiple sclerosis in a Tunisian population.
Topics: Adolescent; Adult; Chemokine CCL2; Child; Confidence Intervals; Female; Gene Frequency; Genome-Wide Association Study; Genotype; Humans; Isoleucine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, CCR2; Tunisia; Valine; Young Adult | 2010 |
Conformation dependence of the DαDα stretch mode in peptides: Side-chain influence in dipeptide structures.
Topics: Alanine; Dipeptides; Glycine; Isoleucine; Leucine; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Protein Conformation; Serine; Valine; Water | 2010 |
High-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination.
Topics: Amino Acid Sequence; Carbon Isotopes; Deuterium; Escherichia coli; Fourier Analysis; Humans; Isoleucine; Leucine; Methylation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Quaternary; Proteins; Valine | 2010 |
Dietary limitation of isoleucine and valine in diets based on maize, soybean meal, and meat and bone meal for broiler chickens.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biological Products; Body Weight; Chickens; Diet; Glycine max; Isoleucine; Meat; Minerals; Valine; Zea mays | 2010 |
A simple strategy for ¹³C, ¹H labeling at the Ile-γ2 methyl position in highly deuterated proteins.
Topics: Carbon Isotopes; Deuterium; Isoleucine; Isotope Labeling; Leucine; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine; Vitamin B 12 | 2010 |
The renal clearance of essential amino acids; tryptophane, leucine, isoleucine and valine.
Topics: Amino Acids; Amino Acids, Essential; Humans; Isoleucine; Kidney; Leucine; Tryptophan; Valine | 1946 |
The isoleucine, leucine and valine requirements of the chick.
Topics: Animals; Chickens; Isoleucine; Leucine; Valine | 1946 |
Microbiological determination of free leucine, isoleucine, valine, and threonine in dog plasma.
Topics: Amino Acids; Animals; Blood; Dogs; Isoleucine; Leucine; Plasma; Threonine; Valine | 1945 |
The renal reabsorption of amino acids in dogs; valine, leucine and isoleucine.
Topics: Amino Acids; Animals; Dogs; Isoleucine; Kidney; Leucine; Renal Reabsorption; Valine | 1946 |
GSTP1 Ile105Val polymorphism in astrocytomas and glioblastomas.
Topics: Adolescent; Adult; Aged; Astrocytoma; Base Sequence; Brain Neoplasms; Case-Control Studies; DNA Primers; Female; Glioblastoma; Glutathione Transferase; Humans; Isoleucine; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Valine; Young Adult | 2010 |
Alanine methyl groups as NMR probes of molecular structure and dynamics in high-molecular-weight proteins.
Topics: Alanine; Isoleucine; Leucine; Malate Synthase; Molecular Dynamics Simulation; Molecular Probes; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Proteins; Valine | 2010 |
An autopsied case of V180I Creutzfeldt-Jakob disease presenting with panencephalopathic-type pathology and a characteristic prion protein type.
Topics: Aged; Autopsy; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Fatal Outcome; Female; Humans; Isoleucine; Prion Diseases; Subacute Sclerosing Panencephalitis; Valine | 2011 |
Cold sensitivity in rice (Oryza sativa L.) is strongly correlated with a naturally occurring I99V mutation in the multifunctional glutathione transferase isoenzyme GSTZ2.
Topics: Acclimatization; Amino Acid Sequence; Amino Acid Substitution; Cold Temperature; Gene Expression Regulation, Plant; Genes, Plant; Genotype; Glutathione Transferase; Isoenzymes; Isoleucine; Molecular Sequence Data; Mutation, Missense; Oryza; Plants, Genetically Modified; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Valine | 2011 |
Validation of plasma branched chain amino acids as biomarkers in Huntington disease.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Biomarkers; Early Diagnosis; Female; Genotype; Heterozygote; Humans; Huntingtin Protein; Huntington Disease; Isoleucine; Leucine; Linear Models; Male; Middle Aged; Nerve Tissue Proteins; Nuclear Proteins; Predictive Value of Tests; Severity of Illness Index; Trinucleotide Repeat Expansion; Valine | 2011 |
Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.
Topics: Absorption; Alanine; Amino Acids; Circular Dichroism; Dinitrobenzenes; Glycine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Quinidine; Quinine; Stereoisomerism; Valine; Vibration | 2011 |
Role of complement factor H I62V and age-related maculopathy susceptibility 2 A69S variants in the clinical expression of polypoidal choroidal vasculopathy.
Topics: Adult; Age of Onset; Alanine; Choroid; Choroid Diseases; Choroidal Neovascularization; Chromatography; Complement Factor H; Cross-Sectional Studies; Fundus Oculi; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Incidence; Isoleucine; Phenotype; Polyps; Proteins; Retinal Detachment; Retinal Hemorrhage; Retinal Pigment Epithelium; Serine; Valine; Vascular Diseases | 2011 |
A novel pathogenic PSEN1 mutation in a family with Alzheimer's disease: phenotypical and neuropathological features.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Brain; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Isoleucine; Male; Mental Status Schedule; Middle Aged; Mutation; Phenotype; Presenilin-1; Valine | 2011 |
Isoleucine 259 and isoleucine 260 residues in Streptococcus gordonii soluble inorganic pyrophosphatase play an important role in enzyme activity.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Glutamic Acid; Inorganic Pyrophosphatase; Isoleucine; Mutagenesis, Site-Directed; Streptococcus gordonii; Valine | 2011 |
Determination of the fourth and fifth limiting amino acids in broilers fed on diets containing maize, soybean meal and poultry by-product meal from 28 to 42 d of age.
Topics: Amino Acids; Animal Feed; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Chickens; Glycine max; Isoleucine; Poultry Products; Valine; Zea mays | 2011 |
An amino acid mixture enhances insulin-stimulated glucose uptake in isolated rat epitrochlearis muscle.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Biological Transport; Blotting, Western; Cysteine; Deoxyglucose; Energy Metabolism; GTPase-Activating Proteins; In Vitro Techniques; Insulin; Isoleucine; Kinetics; Leucine; Male; Methionine; Muscle, Skeletal; Phosphocreatine; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Tubulin; Valine | 2011 |
Synergistic effects of sour taste and low temperature in suppressing the bitterness of Aminoleban® EN.
Topics: Adult; Amino Acids, Branched-Chain; Cold Temperature; Drug Synergism; Enteral Nutrition; Female; Humans; Isoleucine; Leucine; Reference Values; Sweetening Agents; Taste Perception; Taste Threshold; Valine; Young Adult | 2011 |
Synthesis of the amino acid conjugates of epi-jasmonic acid.
Topics: Alanine; Cyclopentanes; Isoleucine; Molecular Structure; Oxylipins; Plants; Stereoisomerism; Valine | 2012 |
Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects.
Topics: Amino Acids, Branched-Chain; Ammonia; Female; Femoral Artery; Femoral Vein; Glutamine; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Metabolic Clearance Rate; Middle Aged; Muscle, Skeletal; Positron-Emission Tomography; Radial Artery; Regional Blood Flow; Thigh; Tomography, X-Ray Computed; Valine | 2011 |
Isopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atoms.
Topics: Binding Sites; Biochemistry; Crystallography, X-Ray; Fungal Proteins; Hydrophobic and Hydrophilic Interactions; Iron; Isoleucine; Models, Molecular; Oligopeptides; Oxidation-Reduction; Oxidoreductases; Oxygen; Penicillins; Protein Binding; Substrate Specificity; Sulfur; Valine | 2011 |
Functional splicing assay of DSPP mutations in hereditary dentin defects.
Topics: Adenine; Codon, Nonsense; Conserved Sequence; Cytosine; Dentin Dysplasia; Dentinogenesis Imperfecta; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Genotype; Guanine; Humans; Isoleucine; Mutagenesis; Mutation; Mutation, Missense; Phenotype; Phosphoproteins; Polymerase Chain Reaction; Proline; RNA Splice Sites; RNA Splicing; Sialoglycoproteins; Thymine; Valine | 2011 |
Structure-based prediction of methyl chemical shifts in proteins.
Topics: Crystallography, X-Ray; Databases, Protein; Isoleucine; Leucine; Methane; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Ubiquitin; Valine | 2011 |
Two novel mutations in the gene EDAR causing autosomal recessive hypohidrotic ectodermal dysplasia.
Topics: Adenine; Child; Chromosomes, Human, Pair 2; Consanguinity; Cytosine; Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive; Edar Receptor; Exons; Genetic Linkage; Genotyping Techniques; Humans; Isoleucine; Microsatellite Repeats; Mutagenesis, Insertional; Mutation; Mutation, Missense; Pakistan; Pedigree; RNA Splice Sites; Sequence Analysis, DNA; Threonine; Thymine; Valine; Young Adult | 2011 |
Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: a multi-electrode array study.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Electrodes; Excitatory Postsynaptic Potentials; Hippocampus; Humans; In Vitro Techniques; Isoleucine; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; Synapses; tau Proteins; Time Factors; Valine | 2011 |
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Genetic Predisposition to Disease; Humans; Hydrophobic and Hydrophilic Interactions; Isoleucine; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Prion Diseases; Prions; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Signal Transduction; Valine | 2011 |
Branched-chain amino acids complex inhibits melanogenesis in B16F0 melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Agaricales; Amino Acids; Animals; Arbutin; Biocatalysis; Biosynthetic Pathways; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Free Radical Scavengers; Isoleucine; Leucine; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Picrates; Valine | 2012 |
Novel p.Ile151Val mutation in VCP in a patient of African American descent with sporadic ALS.
Topics: Adenosine Triphosphatases; Aged; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Black or African American; Cell Cycle Proteins; Fatal Outcome; Female; Humans; Isoleucine; Molecular Sequence Data; Mutation; Valine; Valosin Containing Protein | 2011 |
Analysis of the LIV system of Campylobacter jejuni reveals alternative roles for LivJ and LivK in commensalism beyond branched-chain amino acid transport.
Topics: Amino Acids, Branched-Chain; Animals; Bacterial Proteins; Biological Transport; Campylobacter Infections; Campylobacter jejuni; Chickens; Humans; Intestines; Isoleucine; Leucine; Periplasmic Binding Proteins; Symbiosis; Valine | 2011 |
Backbone and sidechain methyl Ile (δ1), Leu and Val chemical shift assignments of RDE-4 (1-243), an RNA interference initiation protein in C. elegans.
Topics: Amino Acids; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Isoleucine; Leucine; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; RNA Interference; RNA-Binding Proteins; Valine | 2012 |
Isoleucine or valine deprivation stimulates fat loss via increasing energy expenditure and regulating lipid metabolism in WAT.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Adiposity; Animals; Energy Intake; Energy Metabolism; Fatty Acid Synthases; Food, Formulated; Gene Expression; Ion Channels; Isoleucine; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Oxygen Consumption; Uncoupling Protein 1; Valine; Weight Loss | 2012 |
CCR2 polymorphism in chronic renal failure patients requiring long-term hemodialysis.
Topics: Adult; Aged; Female; Gene Frequency; Genotype; Humans; Isoleucine; Kidney Failure, Chronic; Male; Middle Aged; Polymorphism, Genetic; Receptors, CCR2; Renal Dialysis; Time Factors; Valine | 2011 |
Novel L-amino acid oxidase with algicidal activity against toxic cyanobacterium Microcystis aeruginosa synthesized by a bacterium Aquimarina sp.
Topics: Antibiosis; Bacterial Proteins; Chlorophyta; Culture Media; Eutrophication; Flavobacteriaceae; Isoleucine; L-Amino Acid Oxidase; Leucine; Methionine; Microcystis; Taiwan; Valine | 2011 |
Disorders of the degradation of branched chain amino acids: what is new in clinics and laboratories?
Topics: Amino Acids, Branched-Chain; Animals; Germany; Humans; Isoleucine; Leucine; Metabolism, Inborn Errors; Mice; Societies, Medical; Valine | 2012 |
Molecular identification of a further branched-chain aminotransferase 7 (BCAT7) in tomato plants.
Topics: Amino Acid Sequence; Amino Acids, Branched-Chain; Arabidopsis; Chromosome Mapping; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Isoleucine; Leucine; Molecular Sequence Data; Plant Growth Regulators; Plants, Genetically Modified; Sequence Homology, Amino Acid; Solanum lycopersicum; Transaminases; Valine | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis.
Topics: Adult; CX3C Chemokine Receptor 1; Female; Genetic Predisposition to Disease; Haplotypes; Humans; Isoleucine; Male; Methionine; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polymorphism, Genetic; Receptors, Chemokine; Threonine; Valine | 2012 |
Correlation of the occurrence of YMDD mutations with HBV genotypes, HBV-DNA levels, and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment.
Topics: Adult; Aged; Alanine Transaminase; Amino Acids; Antiviral Agents; Aspartic Acid; China; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Isoleucine; Lamivudine; Logistic Models; Male; Methionine; Middle Aged; Mutation; Retrospective Studies; Tyrosine; Valine | 2012 |
Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons.
Topics: Animals; Cells, Cultured; Cerebellum; Glutamic Acid; Isoleucine; Leucine; Mice; Neurons; Synaptic Transmission; Valine | 2012 |
Study and reengineering of the binding sites and allosteric regulation of biosynthetic threonine deaminase by isoleucine and valine in Escherichia coli.
Topics: Allosteric Regulation; Binding Sites; Computational Biology; Escherichia coli; Isoleucine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Engineering; Threonine Dehydratase; Valine | 2013 |
A novel mutation I215V in the PRNP gene associated with Creutzfeldt-Jakob and Alzheimer's diseases in three patients with divergent clinical phenotypes.
Topics: 14-3-3 Proteins; Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Creutzfeldt-Jakob Syndrome; Glial Fibrillary Acidic Protein; Humans; Isoleucine; Male; Models, Molecular; Mutation; Phenotype; Prion Proteins; Prions; Spain; Valine | 2013 |
Activation of α-secretase by curcumin-aminoacid conjugates.
Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid Precursor Protein Secretases; Curcumin; Enzyme Activation; HEK293 Cells; Humans; Isoleucine; Membrane Proteins; Phenylalanine; Valine | 2012 |
Fractalkine gene receptor polymorphism in patients with multiple sclerosis.
Topics: Adolescent; Adult; Age of Onset; Analysis of Variance; Chemokine CX3CL1; Disability Evaluation; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Male; Methionine; Middle Aged; Multiple Sclerosis; Polymorphism, Single Nucleotide; Statistics, Nonparametric; Threonine; Valine; Young Adult | 2013 |
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.
Topics: Adolescent; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Body Mass Index; Child; Child Nutrition Disorders; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Longitudinal Studies; Male; Massachusetts; Obesity; Predictive Value of Tests; Valine | 2013 |
Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats.
Topics: Amino Acids, Branched-Chain; Animals; Blotting, Western; Hindlimb Suspension; Isoleucine; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Muscular Disorders, Atrophic; Organ Size; Rats; Rats, Sprague-Dawley; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Valine | 2012 |
Structural and kinetic effects on changes in the CO(2) binding pocket of human carbonic anhydrase II.
Topics: Alanine; Carbon Dioxide; Carbonic Anhydrase II; Catalysis; Catalytic Domain; Crystallography, X-Ray; Humans; Isoleucine; Kinetics; Leucine; Mutagenesis, Site-Directed; Valine | 2012 |
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Topics: Adult; Amino Acids; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Phenylalanine; Tyrosine; Valine; Young Adult | 2013 |
Milk protein responses in dairy cows to changes in postruminal supplies of arginine, isoleucine, and valine.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Arginine; Cattle; Diet; Female; Isoleucine; Lactation; Milk; Milk Proteins; Valine | 2013 |
The coil-to-helix transition in IlvN regulates the allosteric control of Escherichia coli acetohydroxyacid synthase I.
Topics: Acetolactate Synthase; Alkylation; Allosteric Regulation; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Isoleucine; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Subunits; Valine | 2013 |
Aspartate protects Lactobacillus casei against acid stress.
Topics: Amino Acids; Arginine; Aspartic Acid; Bacterial Proteins; Hydrogen-Ion Concentration; Isoleucine; Lacticaseibacillus casei; Leucine; Valine | 2013 |
Amino acid turnover by human oocytes is influenced by gamete developmental competence, patient characteristics and gonadotrophin treatment.
Topics: Age Factors; Alanine; Amino Acids; Arginine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Female; Follicle Stimulating Hormone; Glutamic Acid; Glutamine; Gonadotropins; Humans; Infertility, Female; Isoleucine; Kinetics; Lysine; Metaphase; Oocytes; Ovulation Induction; Polycystic Ovary Syndrome; Serine; Valine | 2013 |
A mutation in NPAS3 segregates with mental illness in a small family.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Cells, Cultured; DNA Mutational Analysis; Family Health; Female; Green Fluorescent Proteins; Humans; Isoleucine; Male; Mice; Mutation; Nerve Tissue Proteins; Neurons; Schizophrenia; Transcription Factors; Transfection; Valine | 2014 |
Supplemental leucine and isoleucine affect expression of cationic amino acid transporters and myosin, serum concentration of amino acids, and growth performance of pigs.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animal Feed; Animals; Cationic Amino Acid Transporter 1; Diet; Dietary Supplements; Gene Expression; Isoleucine; Jejunum; Leucine; Muscles; Myosins; Swine; Valine; Weight Gain | 2013 |
Impact of isolated germline JAK2V617I mutation on human hematopoiesis.
Topics: Adult; Amino Acid Substitution; Animals; Cells, Cultured; Family; Female; Germ-Line Mutation; Hematopoiesis; Humans; Isoleucine; Janus Kinase 2; Male; Mice; Mice, Inbred NOD; Mice, Transgenic; Middle Aged; Myeloproliferative Disorders; Valine | 2013 |
Novel EDA p.Ile260Ser mutation linked to non-syndromic hypodontia.
Topics: Adolescent; Anodontia; Conserved Sequence; Cuspid; Ectodermal Dysplasia; Ectodysplasins; Exons; Female; Guanine; Humans; Incisor; Isoleucine; Leucine; Male; MSX1 Transcription Factor; Mutation, Missense; PAX9 Transcription Factor; Pedigree; Phenotype; Sequence Homology, Amino Acid; Serine; Structural Homology, Protein; Thymine; Tumor Necrosis Factors; Valine | 2013 |
Transcriptome analysis of skin photoaging in chinese females reveals the involvement of skin homeostasis and metabolic changes.
Topics: Adult; Cluster Analysis; Computational Biology; Female; Gene Expression Profiling; Gene Expression Regulation; Homeostasis; Humans; Isoleucine; Leucine; Metabolic Networks and Pathways; Middle Aged; Molecular Sequence Annotation; Signal Transduction; Skin; Skin Aging; Sunlight; Transforming Growth Factor beta; Valine | 2013 |
Uniquely localized intra-molecular amino acid concentrations at the glycolytic enzyme catalytic/active centers of Archaea, Bacteria and Eukaryota are associated with their proposed temporal appearances on earth.
Topics: Amino Acid Sequence; Amino Acids; Archaea; Bacteria; Catalytic Domain; Conserved Sequence; Earth, Planet; Enzymes; Eukaryota; Evolution, Molecular; Isoleucine; Leucine; Logistic Models; Molecular Sequence Data; Valine | 2013 |
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase.
Topics: Allosteric Regulation; Animals; Binding Sites; Chromatography, Liquid; Crystallography, X-Ray; Isoleucine; Kinetics; Leucine; Male; Mice; Mice, Inbred ICR; Mitochondrial Proteins; Models, Molecular; Molecular Structure; Mutation; Phenylpropionates; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Structure, Tertiary; Tandem Mass Spectrometry; Valine | 2013 |
I405V polymorphism of CETP gene and lipid profile in women with endometriosis.
Topics: Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Cholesterol Ester Transfer Proteins; Cross-Sectional Studies; Endometriosis; Female; Genetic Predisposition to Disease; Humans; Isoleucine; Lipid Metabolism; Lipids; Polymorphism, Single Nucleotide; Uterine Diseases; Valine; Young Adult | 2013 |
Kinetic proofreading at single molecular level: aminoacylation of tRNA(Ile) and the role of water as an editor.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Algorithms; Bacterial Proteins; Computer Simulation; Hydrolysis; Isoleucine; Isoleucine-tRNA Ligase; Kinetics; Models, Chemical; RNA, Transfer, Ile; Stochastic Processes; Transfer RNA Aminoacylation; Valine; Water | 2013 |
Association GSTT1, GSTM1 and GSTP1 (Ile105Val) genetic polymorphisms in mothers with risk of congenital malformations in their children in Western Siberia: a case-control study.
Topics: Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Congenital Abnormalities; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Infant, Newborn; Isoleucine; Mothers; Polymorphism, Genetic; Pregnancy; Risk Factors; Siberia; Valine; Young Adult | 2013 |
Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings.
Topics: Acids, Acyclic; Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Isoleucine; Large Neutral Amino Acid-Transporter 1; Methylation; Mice; Mice, Transgenic; Molecular Targeted Therapy; Organ Specificity; Phenylalanine; Phenylketonurias; Protein Conformation; Protein Folding; Valine | 2013 |
A novel variant mutation of transthyretin Ile73Val-related amyloidotic polyneuropathy in Taiwanese.
Topics: Action Potentials; Amyloid Neuropathies, Familial; Family Health; Female; Genetic Testing; Humans; Isoleucine; Male; Middle Aged; Mutation; Neural Conduction; Taiwan; Valine | 2013 |
Conserved pyridoxal protein that regulates Ile and Val metabolism.
Topics: Bacillus subtilis; Butyrates; Carrier Proteins; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genetic Complementation Test; Isoleucine; Protein Binding; Pyridoxal Phosphate; Saccharomyces cerevisiae; Valine | 2013 |
Perdeuteration and methyl-selective (1)H, (13)C-labeling by using a Kluyveromyces lactis expression system.
Topics: Carbon Isotopes; Deuterium; Gene Expression; Isoleucine; Isotope Labeling; Kluyveromyces; Leucine; Maltose-Binding Proteins; Nuclear Magnetic Resonance, Biomolecular; Proteins; Transaminases; Valine | 2013 |
Polymorphisms of glutathione-S-transferases M1, T1, P1 and susceptibility to colorectal cancer in a sample of the Tunisian population.
Topics: Adult; Aged; Alleles; Case-Control Studies; Colorectal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Male; Middle Aged; Polymorphism, Genetic; Tunisia; Valine | 2014 |
Polymorphism p.Val231Ile alters substrate selectivity of drug-metabolizing arylamine N-acetyltransferase 2 (NAT2) isoenzyme of rhesus macaque and human.
Topics: Amino Acid Substitution; Animals; Arylamine N-Acetyltransferase; Catalytic Domain; Enzyme Stability; Humans; Isoenzymes; Isoleucine; Macaca mulatta; Models, Molecular; Polymorphism, Single Nucleotide; Substrate Specificity; Valine | 2014 |
A NMR experiment for simultaneous correlations of valine and leucine/isoleucine methyls with carbonyl chemical shifts in proteins.
Topics: Isoleucine; Leucine; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Proteins; Valine | 2014 |
Backbone and stereospecific (13)C methyl Ile (δ1), Leu and Val side-chain chemical shift assignments of Crc.
Topics: Bacterial Proteins; Isoleucine; Leucine; Nuclear Magnetic Resonance, Biomolecular; Pseudomonas syringae; Repressor Proteins; Stereoisomerism; Valine | 2015 |
Genetic, cell biological, and clinical interrogation of the CFTR mutation c.3700 A>G (p.Ile1234Val) informs strategies for future medical intervention.
Topics: Adolescent; Adult; Aminopyridines; Animals; Benzodioxoles; Cell Line; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; HEK293 Cells; Homozygote; Humans; Isoleucine; Male; Mutation, Missense; Qatar; RNA Splicing; Valine | 2014 |
Experimental evaluation of the effect of a modified port-location mode on the performance of a three-zone simulated moving-bed process for the separation of valine and isoleucine.
Topics: Adsorption; Chromatography, Liquid; Computer Simulation; Isoleucine; Valine | 2014 |
Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up.
Topics: Aged; Amino Acids; Arginine; Betaine; Body Mass Index; Fasting; Female; Humans; Hypertriglyceridemia; Isoleucine; Leucine; Male; Middle Aged; Odds Ratio; Phenylalanine; Proline; Risk Factors; ROC Curve; Triglycerides; Valine | 2014 |
Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice.
Topics: Amino Acids, Branched-Chain; AMP-Activated Protein Kinases; Animals; Blood Glucose; Blotting, Western; Cell Line; Gluconeogenesis; Glucose-6-Phosphatase; Hep G2 Cells; Hepatocytes; Humans; Insulin Resistance; Isoleucine; Male; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Valine | 2014 |
Characterization of the low-temperature activity of Sulfolobus tokodaii glucose-1-dehydrogenase mutants.
Topics: Amino Acid Substitution; Archaeal Proteins; Biocatalysis; Cold Temperature; Enzyme Stability; Glucose; Glucose 1-Dehydrogenase; Hot Temperature; Isoleucine; Kinetics; Mutation; NADP; Recombinant Proteins; Structural Homology, Protein; Sulfolobus; Thermodynamics; Valine | 2014 |
Spatially selective heteronuclear multiple-quantum coherence spectroscopy for biomolecular NMR studies.
Topics: Isoleucine; Isotopes; Leucine; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Proteins; Solutions; Valine | 2014 |
TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor.
Topics: Biological Transport; Calcium-Binding Proteins; Cell Membrane; Circular Dichroism; Escherichia coli; Isoleucine; Leucine; Monosaccharide Transport Proteins; Nuclear Magnetic Resonance, Biomolecular; Periplasmic Binding Proteins; Protein Binding; Protein Structure, Secondary; Staining and Labeling; Tryptophan; Valine | 2014 |
Polymorphisms of NRF2 and NRF2 target genes in urinary bladder cancer patients.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alanine; Epistasis, Genetic; Female; Gene Deletion; Gene-Environment Interaction; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Male; Middle Aged; Neoplasm Grading; NF-E2-Related Factor 2; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Risk Factors; Sex Factors; Smoking; Superoxide Dismutase; Urinary Bladder Neoplasms; Valine | 2014 |
The physiological target for LeuRS translational quality control is norvaline.
Topics: Aerobiosis; Crystallography, X-Ray; Escherichia coli; Isoleucine; Kinetics; Leucine-tRNA Ligase; Methionine; Protein Biosynthesis; Protein Conformation; RNA Editing; Valine | 2014 |
Selective methyl labeling of eukaryotic membrane proteins using cell-free expression.
Topics: Bacterial Outer Membrane Proteins; Carbon Isotopes; Cell-Free System; Cost-Benefit Analysis; Escherichia coli; Escherichia coli Proteins; Humans; Hydrogen; Hydrolases; Hydrolysis; Inclusion Bodies; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Membrane Proteins; Micelles; Valine | 2014 |
[Plasma amino acid profiling of "same symptom for different disease" in Uyghur medicine based on high-performance liquid chromatography].
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Cystine; Humans; Isoleucine; Leucine; Medicine, Chinese Traditional; Neoplasms; Serine; Tyrosine; Valine | 2014 |
Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16.
Topics: Acetolactate Synthase; Bacterial Proteins; Biosynthetic Pathways; Butyrates; Culture Media; Cupriavidus necator; DNA, Bacterial; Hemiterpenes; Hydro-Lyases; Isoleucine; Keto Acids; Ketol-Acid Reductoisomerase; Leucine; Mutagenesis, Site-Directed; Valine | 2015 |
Valine, isoleucine, arginine and glycine supplementation of low-protein diets for broiler chickens during the starter and grower phases.
Topics: Animal Husbandry; Animals; Arginine; Chickens; Diet, Protein-Restricted; Dietary Supplements; Glycine; Isoleucine; Valine; Weight Gain | 2014 |
Determination of essentiality and regulatory function of staphylococcal YeaZ in branched-chain amino acid biosynthesis.
Topics: Bacterial Proteins; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Isoleucine; Leucine; Promoter Regions, Genetic; RNA; Staphylococcus aureus; Transcription Factors; Valine | 2015 |
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease.
Topics: Carnitine; Female; Gene Expression Profiling; Humans; Isoleucine; Leucine; Male; Metabolomics; Non-alcoholic Fatty Liver Disease; Signal Transduction; Valine | 2015 |
Role of BrnQ1 and BrnQ2 in branched-chain amino acid transport and virulence in Staphylococcus aureus.
Topics: Animals; Bacterial Proteins; Biological Transport; Carrier Proteins; Culture Media; Gene Expression Regulation, Bacterial; Humans; Isoleucine; Kidney; Kinetics; Leucine; Liver; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mutation; Repressor Proteins; Staphylococcal Infections; Substrate Specificity; Valine; Virulence | 2015 |
Association of single-nucleotide polymorphisms in the IRF6 gene with non-syndromic cleft lip with or without cleft palate in the Xinjiang Uyghur population.
Topics: 5' Flanking Region; 5' Untranslated Regions; Adenine; Case-Control Studies; Cleft Lip; Cleft Palate; Cytosine; Exons; Gene Frequency; Genes, Dominant; Genes, Recessive; Genetic Predisposition to Disease; Genotype; Guanine; Haplotypes; Humans; Infant; Interferon Regulatory Factors; Introns; Isoleucine; Linkage Disequilibrium; Mutation, Missense; Polymorphism, Single Nucleotide; Serine; Valine | 2015 |
Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies.
Topics: Carbon Isotopes; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Methylation; Peptide Mapping; Proteins; Protons; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Valine | 2015 |
The tRNA A76 Hydroxyl Groups Control Partitioning of the tRNA-dependent Pre- and Post-transfer Editing Pathways in Class I tRNA Synthetase.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Catalysis; Escherichia coli; Hydrolysis; Isoleucine; Isoleucine-tRNA Ligase; Phosphates; Protein Conformation; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Transfer; Substrate Specificity; Valine | 2015 |
Engineering Corynebacterium crenatum to produce higher alcohols for biofuel using hydrolysates of duckweed (Landoltia punctata) as feedstock.
Topics: Alcohols; Araceae; Biofuels; Butanols; Corynebacterium; Fermentation; Gene Expression; Glucose; Hydrolysis; Isoleucine; Leucine; Metabolic Engineering; Metabolic Networks and Pathways; Plant Extracts; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Starch; Valine | 2015 |
Synthesis and Anti-microbial Activity of Novel Phosphatidylethanolamine-N-amino Acid Derivatives.
Topics: Amino Acids; Bacteria; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Egg Yolk; Fungi; Glycine; Isoleucine; Lecithins; Leucine; Phenylalanine; Phosphatidylethanolamines; Valine | 2015 |
Brachydactyly Type C patient with compound heterozygosity for p.Gly319Val and p.Ile358Thr variants in the GDF5 proregion: benign variants or mutations?
Topics: Amino Acid Sequence; Amino Acid Substitution; Brachydactyly; Child, Preschool; Female; Glycine; Growth Differentiation Factor 5; Heterozygote; Humans; Isoleucine; Molecular Sequence Data; Mutation, Missense; Pedigree; Promoter Regions, Genetic; Threonine; Valine | 2015 |
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.
Topics: Adipocytes; Animals; Crystallography, X-Ray; Humans; Isoleucine; Leucine; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondrial Proteins; Models, Molecular; Pyrazoles; Pyrimidinones; Structure-Activity Relationship; Transaminases; Valine | 2015 |
GLUT2 and TAS1R2 Polymorphisms and Susceptibility to Dental Caries.
Topics: Adolescent; Case-Control Studies; Child; Czech Republic; Dental Caries; Dental Caries Susceptibility; Dental Plaque Index; Dental Restoration, Permanent; DMF Index; Female; Gene Frequency; Genetic Variation; Genotype; Glucose Transporter Type 2; Guanine; Humans; Isoleucine; Male; Periodontal Index; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Threonine; Thymine; Tooth Extraction; Valine | 2015 |
Simultaneous determination of leucine, isoleucine and valine in Beagle dog plasma by HPLC-MS/MS and its application to a pharmacokinetic study.
Topics: Administration, Oral; Animals; Calibration; Chromatography, High Pressure Liquid; Dogs; Female; Isoleucine; Leucine; Male; Plasma; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry; Valine | 2015 |
Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2.
Topics: Adenosine Triphosphate; Animals; Catalytic Domain; Crystallography, X-Ray; Isoleucine; Leucine; Methylation; Mitogen-Activated Protein Kinase 1; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleotides; Peptides; Protein Binding; Protein Conformation; Rats; Valine | 2015 |
New hydrophobic L-amino acid salts: maleates of L-leucine, L-isoleucine and L-norvaline.
Topics: Amino Acids; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Lysine; Maleates; Molecular Structure; Valine | 2015 |
Impact of HER2 codon 655 polymorphism and expression of HER2 and HER3 in non small cell lung cancer patients.
Topics: Adenocarcinoma; Aged; Codon; Female; Gene Expression Regulation; Humans; Isoleucine; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Prognosis; Receptor, ErbB-2; Receptor, ErbB-3; Statistics as Topic; Valine | 2015 |
A NOVEL DOUBLE MUTATION VAL648ILE AND VAL804LEU OF RET PROTO-ONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.
Topics: Adrenal Gland Neoplasms; Amino Acid Substitution; Base Sequence; DNA Mutational Analysis; Female; Germ-Line Mutation; Humans; Isoleucine; Leucine; Middle Aged; Molecular Sequence Data; Multiple Endocrine Neoplasia Type 2a; Pedigree; Pheochromocytoma; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Valine | 2015 |
Regulation of indole-3-acetic acid biosynthesis by branched-chain amino acids in Enterobacter cloacae UW5.
Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Biosynthetic Pathways; Carboxy-Lyases; Cloning, Molecular; Down-Regulation; Enterobacter cloacae; Indoleacetic Acids; Isoleucine; Leucine; Promoter Regions, Genetic; Soil Microbiology; Valine | 2015 |
Optimisation of broiler chicken responses from 0 to 7 d of age to dietary leucine, isoleucine and valine using Taguchi and mathematical methods.
Topics: Animal Feed; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Chickens; Diet; Dietary Supplements; Digestion; Glycine max; Isoleucine; Leucine; Male; Models, Biological; Nutritional Requirements; Triticum; Valine; Zea mays | 2015 |
Biochemical Characterization of Branched Chain Amino Acids Uptake in Trypanosoma cruzi.
Topics: Adenosine Triphosphate; Amino Acid Transport Systems; Amino Acids, Branched-Chain; Animals; Cell Membrane; Chagas Disease; Isoleucine; Kinetics; Leucine; Temperature; Trypanosoma cruzi; Valine | 2016 |
Arrested Phase Separation of Elastin-like Polypeptide Solutions Yields Stiff, Thermoresponsive Gels.
Topics: Amino Acid Motifs; Biocompatible Materials; Elastin; Hydrogels; Isoleucine; Molecular Mimicry; Molecular Sequence Data; Peptides; Phase Transition; Rheology; Shear Strength; Transition Temperature; Valine | 2015 |
Functional roles of a predicted branched chain aminotransferase encoded by the LkBAT1 gene of the yeast Lachancea kluyveri.
Topics: Amino Acids, Branched-Chain; Fungal Proteins; Isoleucine; Leucine; Mitochondria; Saccharomycetales; Transaminases; Valine | 2015 |
CH3-specific NMR assignment of alanine, isoleucine, leucine and valine methyl groups in high molecular weight proteins using a single sample.
Topics: Alanine; Isoleucine; Leucine; Malate Synthase; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Valine | 2015 |
Clusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability.
Topics: Amino Acid Sequence; Animals; Databases, Protein; Fibroblast Growth Factor 1; Humans; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Micrococcal Nuclease; Models, Molecular; Myoglobin; Protein Conformation; Protein Stability; Proteins; Ribonuclease H; Sequence Alignment; Staphylococcus; Valine | 2016 |
Integrative drug efficacy assessment of Danggui and European Danggui using NMR-based metabolomics.
Topics: Angelica sinensis; Animals; Drugs, Chinese Herbal; Isoleucine; Ketone Bodies; Leucine; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Metabolic Networks and Pathways; Metabolomics; Rats; Serum; Valine | 2016 |
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Topics: Actins; Amino Acids, Branched-Chain; Ammonia; Carbon-Carbon Ligases; Cells, Cultured; Child; Fibroblasts; Hemodynamics; Hepatocytes; Humans; Isoleucine; Liver; Methylmalonyl-CoA Decarboxylase; Mutation; Propionic Acidemia; Urea; Valine | 2016 |
Maintenance valine, isoleucine, and tryptophan requirements for poultry.
Topics: Animal Feed; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Isoleucine; Male; Tryptophan; Valine | 2016 |
Living related versus deceased donor liver transplantation for maple syrup urine disease.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adult; Brazil; Child; Child, Preschool; Diet; Female; Follow-Up Studies; Heterozygote; Humans; Isoleucine; Leucine; Liver Transplantation; Living Donors; Male; Maple Syrup Urine Disease; Oxidation-Reduction; Sequence Analysis, DNA; Tissue Donors; Treatment Outcome; Valine | 2016 |
Effects of amino acids supplementation in low crude protein diets on growth performance, carcass traits and serum parameters in finishing gilts.
Topics: Amino Acids; Animals; Body Weight; Diet; Dietary Proteins; Dietary Supplements; Female; Immunoglobulin A; Immunoglobulin G; Isoleucine; Meat; Quantitative Trait, Heritable; Swine; Valine | 2016 |
From Six Gene Polymorphisms of the Antioxidant System, Only GPX Pro198Leu and GSTP1 Ile105Val Modulate the Risk of Acute Myeloid Leukemia.
Topics: Adult; Aged; Antioxidants; Case-Control Studies; Female; Gene Expression Regulation, Leukemic; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoleucine; Leucine; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Mutation; Polymorphism, Genetic; Proline; Reactive Oxygen Species; Risk; Romania; Superoxide Dismutase; Valine | 2016 |
Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations.
Topics: Adult; Aged; Amino Acids, Aromatic; Amino Acids, Branched-Chain; China; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Isoleucine; Leucine; Longitudinal Studies; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Risk Factors; Tyrosine; Valine; Young Adult | 2016 |
Late-onset distal myopathy of the upper limbs due to P.Ile151Val mutation in the valosin-containing protein.
Topics: Adenosine Triphosphatases; Aged; Cell Cycle Proteins; Distal Myopathies; Electromyography; Humans; Isoleucine; Male; Mutation; Upper Extremity; Valine; Valosin Containing Protein | 2016 |
Living donor liver transplantation in maple syrup urine disease - Case series and world's youngest domino liver donor and recipient.
Topics: Allografts; Child, Preschool; Diet, Protein-Restricted; Female; Heterozygote; Humans; Infant; Intraoperative Period; Isoleucine; Leucine; Liver; Liver Cirrhosis, Biliary; Liver Transplantation; Living Donors; Male; Maple Syrup Urine Disease; Perfusion; Postoperative Period; Preoperative Period; Risk; Transplant Recipients; Treatment Outcome; Valine | 2016 |
Down Regulation of Asparagine Synthetase and 3-Phosphoglycerate Dehydrogenase, and the Up-Regulation of Serine Dehydratase in Rat Liver from Intake of Excess Amount of Leucine Are Not Related to Leucine-Caused Amino Acid Imbalance.
Topics: Amino Acids; Animals; Aspartate-Ammonia Ligase; Body Weight; Caseins; Diet; Down-Regulation; Eating; Energy Intake; Growth; Homeostasis; Isoleucine; L-Serine Dehydratase; Leucine; Liver; Male; Phosphoglycerate Dehydrogenase; Rats, Sprague-Dawley; Transcriptional Activation; Up-Regulation; Valine | 2015 |
Suppression of Endogenous Glucose Production by Isoleucine and Valine and Impact of Diet Composition.
Topics: Animals; Blood Glucose; Diet; Diet, High-Fat; Dietary Fats; Dietary Proteins; Gluconeogenesis; Hypothalamus; Insulin Resistance; Isoleucine; Liver; Male; Rats, Sprague-Dawley; Valine | 2016 |
High Leucine Diets Stimulate Cerebral Branched-Chain Amino Acid Degradation and Modify Serotonin and Ketone Body Concentrations in a Pig Model.
Topics: 3-Hydroxybutyric Acid; Amino Acids, Branched-Chain; Animals; Brain; Diet; Female; Intestinal Mucosa; Isoleucine; Keto Acids; Ketone Bodies; Leucine; Liver; Male; Models, Animal; Myocardium; Serotonin; Swine; Valine | 2016 |
Improved Efficiency of Molecular-Gel Formation by Adjusting Preorganization of Amino-Acid-Derived Flexible Molecules: A NMR and Thermodynamic study.
Topics: Gels; Hydrogen Bonding; Isoleucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Thermodynamics; Valine | 2016 |
Effects of Alpha-Ketoglutarate on Glutamine Metabolism in Piglet Enterocytes in Vivo and in Vitro.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Body Weight; Citric Acid Cycle; Diet; Dietary Supplements; Enterocytes; Glutamine; Ileum; Intestinal Mucosa; Intestine, Small; Isoleucine; Jejunum; Ketoglutaric Acids; Lysine; Phenylalanine; RNA, Messenger; Swine; Tyrosine; Valine; Weaning | 2016 |
A case of familial amyloid polyneuropathy (FAP ATTR Ile107Val) with proximal muscle weakness in the lower extremities.
Topics: Aged; Amyloid Neuropathies, Familial; Electromyography; Humans; Isoleucine; Lower Extremity; Male; Muscle Weakness; Neural Conduction; Neurologic Examination; Prealbumin; Quadriceps Muscle; Valine | 2016 |
A conserved patch of hydrophobic amino acids modulates Myb activity by mediating protein-protein interactions.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Chickens; Conserved Sequence; Humans; Hydrophobic and Hydrophilic Interactions; Isoleucine; Molecular Sequence Data; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-myb; Quail; Sequence Homology, Amino Acid; Transcriptional Activation; Valine | 2016 |
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.
Topics: Acetic Acid; Administration, Oral; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Breath Tests; Consciousness; Gastric Emptying; Glycine; Isoleucine; Leucine; Male; Rats, Sprague-Dawley; Serine; Threonine; Valine | 2016 |
Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients.
Topics: Adenosine Monophosphate; Adult; Biomarkers; Biotin; Case-Control Studies; Choline; Cytidine; Fatty Acids; Female; Humans; Injury Severity Score; Isoleucine; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Muscle, Skeletal; Niacinamide; Nucleotides; Oxidative Stress; Principal Component Analysis; Prospective Studies; Serine; Time Factors; Valine; Wounds, Nonpenetrating | 2016 |
Unsaturated amino acids derived from isoleucine trigger early membrane effects on plant cells.
Topics: Cell Membrane; Hydrogen-Ion Concentration; Isoleucine; Membrane Potentials; Mimosa; Osmosis; Plant Cells; Proton-Translocating ATPases; Protons; Radioisotopes; Sucrose; Time Factors; Valine | 2016 |
Highly efficient residue-selective labeling with isotope-labeled Ile, Leu, and Val using a new auxotrophic E. coli strain.
Topics: Escherichia coli; Genetic Engineering; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Proteins; Valine | 2016 |
Glutathione S-Transferase Pi-Ile 105 Val Polymorphism and Susceptibility to T2DM in Population from Turabah Region of Saudi Arabia.
Topics: Adult; Aged; Amplified Fragment Length Polymorphism Analysis; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Humans; Isoleucine; Middle Aged; Polymorphism, Single Nucleotide; Saudi Arabia; Valine | 2016 |
The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin.
Topics: Anticonvulsants; Cell Line, Transformed; Electric Stimulation; Female; Green Fluorescent Proteins; Humans; Isoleucine; Male; Membrane Potentials; Models, Molecular; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenytoin; Sodium Channel Blockers; Tetrodotoxin; Transfection; Valine | 2016 |
(1)H NMR foodomics reveals that the biodynamic and the organic cultivation managements produce different grape berries (Vitis vinifera L. cv. Sangiovese).
Topics: Caffeic Acids; Fruit; gamma-Aminobutyric Acid; Isoleucine; Magnetic Resonance Spectroscopy; Multivariate Analysis; Organic Agriculture; Perchlorates; Proline; Valine; Vitis; Wine | 2016 |
Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder.
Topics: Adult; Amino Acids, Branched-Chain; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Down-Regulation; Energy Metabolism; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Mood Disorders; Nervous System; TOR Serine-Threonine Kinases; Valine | 2016 |
Metabolomic determination of pathogenesis of late-onset preeclampsia.
Topics: Adult; Algorithms; Biomarkers; Case-Control Studies; Female; Humans; Isoleucine; Leucine; Metabolic Networks and Pathways; Metabolomics; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Reproducibility of Results; Valine; Young Adult | 2017 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
Contribution of branched-chain amino acids to purine nucleotide cycle: a pilot study.
Topics: Adolescent; Amino Acids, Branched-Chain; Anthropometry; Athletes; Blood Glucose; Body Composition; Dietary Supplements; Glutamine; Humans; Hypoxanthine; Isoleucine; Leucine; Male; Muscle, Skeletal; Physical Endurance; Pilot Projects; Purine Nucleotides; Running; Sports Nutritional Physiological Phenomena; Uric Acid; Urinalysis; Valine; Young Adult | 2017 |
Detection of intermolecular transferred NOEs in large protein complexes using asymmetric deuteration: HIV-1 gp120 in complex with a CCR5 peptide.
Topics: Binding Sites; Crystallography, X-Ray; Deuterium; HIV Envelope Protein gp120; Humans; Isoleucine; Leucine; Multiprotein Complexes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Binding; Protons; Receptors, CCR5; Tyrosine; Valine | 2016 |
Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Catalytic Domain; Glutamic Acid; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Lysine; Models, Chemical; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Conformation; Pyridoxal Phosphate; Transaminases; Valine | 2016 |
Late-onset episodic ataxia associated with SLC1A3 mutation.
Topics: Acetazolamide; Adult; Age of Onset; Amino Acid Sequence; Amino Acid Substitution; Anticonvulsants; Base Sequence; Cerebellar Ataxia; Excitatory Amino Acid Transporter 1; Female; Gene Expression; Heterozygote; Humans; Isoleucine; Male; Middle Aged; Models, Molecular; Mutation; Pedigree; Phenotype; Sequence Alignment; Valine | 2017 |
Clinical characterization of an APP mutation (V717I) in five Han Chinese families with early-onset Alzheimer's disease.
Topics: Age of Onset; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Apolipoprotein E4; Asian People; Cognition Disorders; DNA Mutational Analysis; Family Health; Female; Humans; Isoleucine; Magnetic Resonance Imaging; Male; Middle Aged; Mood Disorders; Mutation; Neuropsychological Tests; Valine | 2017 |
Potential urinary biomarkers of nephrotoxicity in cyclophosphamide-treated rats investigated by NMR-based metabolic profiling.
Topics: Animals; Biomarkers; Cyclophosphamide; Humans; Isoleucine; Kidney; Leucine; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolomics; Neoplasms; Rats; Taurine; Valine | 2017 |
Frequency of the Val1016Ile mutation on the kdr gene in Aedes aegypti (Diptera: Culicidae) in south Brazil.
Topics: Aedes; Animals; Brazil; Insect Proteins; Insecticide Resistance; Isoleucine; Mutation; Mutation Rate; Sodium Channels; Valine | 2016 |
Revisiting the Val/Ile Mutation in Mammalian and Bacterial Nitric Oxide Synthases: A Spectroscopic and Kinetic Study.
Topics: Amino Acid Substitution; Animals; Arginine; Bacillus subtilis; Bacterial Proteins; Biocatalysis; Biopterins; Catalytic Domain; Coenzymes; Conserved Sequence; Escherichia coli; Gene Expression; Hydrogen Bonding; Isoleucine; Kinetics; Mice; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Recombinant Proteins; Species Specificity; Valine | 2017 |
High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.
Topics: Amino Acids, Branched-Chain; Cell Movement; Humans; Inflammation; Insulin Resistance; Interleukin-6; Isoleucine; Leucine; Leukocytes, Mononuclear; Mechanistic Target of Rapamycin Complex 1; Mitochondria; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Valine | 2017 |
Neurocognitive profiles in MSUD school-age patients.
Topics: Amino Acids, Branched-Chain; Child; Cognition; Early Diagnosis; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Retrospective Studies; Schools; Valine | 2017 |
Modulation of fatty acid composition and growth in Sporosarcina species in response to temperatures and exogenous branched-chain amino acids.
Topics: Amino Acids, Branched-Chain; Cold Temperature; Fatty Acids; Fish Products; Food Microbiology; Isoleucine; Leucine; Sporosarcina; Valine | 2017 |
Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Topics: Aged; Alanine; Amino Acid Substitution; Amyloidosis; Asymptomatic Diseases; Binding Sites; Crystallography, X-Ray; Female; Gene Expression; Humans; Isoleucine; Models, Molecular; Prealbumin; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Recombinant Proteins; Thermodynamics; Valine | 2017 |
Quantum chemical calculations of tryptophan → heme electron and excitation energy transfer rates in myoglobin.
Topics: Density Functional Theory; Electrons; Energy Transfer; Heme; Hydrogen Bonding; Isoleucine; Microscopy; Myoglobin; Protein Conformation; Spectrophotometry, Ultraviolet; Tryptophan; Valine | 2017 |
Whey protein hydrolysate and branched-chain amino acids downregulate inflammation-related genes in vascular endothelial cells.
Topics: Amino Acids, Branched-Chain; Anti-Inflammatory Agents; Caseins; Dairy Products; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Gene Expression; Glutamine; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoleucine; Leucine; Nitric Oxide Synthase Type III; Protein Hydrolysates; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Valine; Vascular Cell Adhesion Molecule-1; Whey Proteins | 2017 |
Serum metabolomics differentiating pancreatic cancer from new-onset diabetes.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Biomarkers, Tumor; Body Mass Index; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diagnosis, Differential; Early Detection of Cancer; Feasibility Studies; Female; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Principal Component Analysis; Sensitivity and Specificity; Serologic Tests; Valine | 2017 |
Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses.
Topics: Capsid Proteins; Child, Preschool; Disease Outbreaks; Enterovirus; Enterovirus A, Human; Epidemics; Female; Hand, Foot and Mouth Disease; Humans; Infant; Isoleucine; Male; Mutation; Phylogeny; Polymorphism, Genetic; Selection, Genetic; Spatio-Temporal Analysis; Valine; Vietnam | 2017 |
Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain.
Topics: Gene Expression Regulation, Fungal; Glutamic Acid; Glutamine; HSP70 Heat-Shock Proteins; Isoleucine; Kinetics; Leucine-tRNA Ligase; Proline; Protein Folding; Reactive Oxygen Species; RNA Editing; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stress, Physiological; Valine | 2017 |
Self-assembly of t-butyloxycarbonyl protected dipeptide methyl esters composed of leucine, isoleucine, and valine into highly organized structures from alcohol and aqueous alcohol mixtures.
Topics: Alcohols; Circular Dichroism; Congo Red; Dipeptides; Erythrocytes; Esters; Hemolysis; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Microscopy, Electron, Scanning; Nanostructures; Spectroscopy, Fourier Transform Infrared; Valine; Water; X-Ray Diffraction | 2017 |
Increased Incretin But Not Insulin Response after Oral versus Intravenous Branched Chain Amino Acids.
Topics: Administration, Intravenous; Administration, Oral; Adult; Amino Acids, Branched-Chain; Blood Glucose; C-Peptide; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Incretins; Insulin; Isoleucine; Leucine; Male; Valine; Young Adult | 2017 |
Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Gene Expression Regulation, Bacterial; Glutamic Acid; Isoleucine; Models, Molecular; Peptide Elongation Factors; Phenylalanine; Protein Binding; Protein Folding; Protein Interaction Domains and Motifs; Sequence Alignment; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors; Transcription, Genetic; Valine | 2017 |
Abscisic acid-regulated protein degradation causes osmotic stress-induced accumulation of branched-chain amino acids in Arabidopsis thaliana.
Topics: Abscisic Acid; Amino Acids, Branched-Chain; Arabidopsis; Arabidopsis Proteins; Droughts; Isoleucine; Leucine; Osmotic Pressure; Plant Growth Regulators; Proteolysis; Stress, Physiological; Transaminases; Valine | 2017 |
3-Hydroxyisobutyrate Dehydrogenase Is Involved in Both, Valine and Isoleucine Degradation in
Topics: Alcohol Oxidoreductases; Arabidopsis; Escherichia coli; Gene Knockdown Techniques; Isoleucine; Plant Proteins; Valine | 2017 |
Topics: Aerobiosis; Batch Cell Culture Techniques; Butyrates; Carbon Isotopes; Citric Acid Cycle; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Magnetic Resonance Spectroscopy; Metabolome; Mitochondria; Pentose Phosphate Pathway; Pichia; Pyruvic Acid; Saccharomyces cerevisiae; Valine | 2017 |
In silico designing of therapeutic protein enriched with branched-chain amino acids for the dietary treatment of chronic liver disease.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cattle; Isoleucine; Lactalbumin; Leucine; Liver; Liver Diseases; Protein Conformation, alpha-Helical; Proteins; Valine | 2017 |
Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Binding Sites; Cloning, Molecular; Cytochromes c; Enzyme Stability; Escherichia coli; Gene Expression; Horses; Isoleucine; Kinetics; Leucine; Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Thermodynamics; Valine | 2017 |
Diversification of Transcriptional Regulation Determines Subfunctionalization of Paralogous Branched Chain Aminotransferases in the Yeast
Topics: Gene Expression Regulation, Fungal; Glutathione Peroxidase; Isoleucine; Leucine; Malates; Mitochondrial Proteins; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators; Transaminases; Transcription Factors; Transcriptional Activation; Valine | 2017 |
The Effects of One Amino Acid Substitutions at the C-Terminal Region of Thermostable L2 Lipase by Computational and Experimental Approach.
Topics: Amino Acid Substitution; Bacterial Proteins; Circular Dichroism; Enzyme Stability; Glutamic Acid; Isoleucine; Lipase; Molecular Dynamics Simulation; Protein Conformation; Recombinant Proteins; Serine; Temperature; Valine | 2018 |
Metabolic effects of p,p'-DDE on Atlantic salmon hepatocytes.
Topics: Animals; Bile Acids and Salts; Carbohydrate Metabolism; Dichlorodiphenyl Dichloroethylene; Diglycerides; DNA Methylation; Dose-Response Relationship, Drug; Hepatocytes; Insecticides; Isoleucine; Leucine; Metabolomics; Salmo salar; Sphingolipids; Transcription, Genetic; Valine | 2018 |
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine | 2018 |
Biochemical features of genetic Creutzfeldt-Jakob disease with valine-to-isoleucine substitution at codon 180 on the prion protein gene.
Topics: Aged, 80 and over; Amino Acid Substitution; Codon; Creutzfeldt-Jakob Syndrome; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Isoleucine; Male; Neocortex; Prion Proteins; Valine | 2018 |
Serum metabolomics study in a group of Parkinson's disease patients from northern India.
Topics: Aged; Alanine; Female; Glutamine; Histidine; Humans; India; Isoleucine; Male; Metabolomics; Middle Aged; Multiple System Atrophy; Parkinson Disease; Proton Magnetic Resonance Spectroscopy; Supranuclear Palsy, Progressive; Valine | 2018 |
Increasing the availability of threonine, isoleucine, valine, and leucine relative to lysine while maintaining an ideal ratio of lysine:methionine alters mammary cellular metabolites, mammalian target of rapamycin signaling, and gene transcription.
Topics: Amino Acid Sequence; Animals; Cattle; Female; Isoleucine; Leucine; Lysine; Mammary Glands, Animal; Methionine; Peptide Fragments; Sirolimus; Threonine; Transcription, Genetic; Valine | 2018 |
Serum metabolomic profile of incident diabetes.
Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Erythritol; Female; Glucose; Humans; Isoleucine; Lactic Acid; Leucine; Male; Maryland; Metabolome; Middle Aged; Minnesota; Mississippi; North Carolina; Prospective Studies; Risk Factors; Trehalose; Valine | 2018 |
High Glucose-Induced Cardiomyocyte Death May Be Linked to Unbalanced Branched-Chain Amino Acids and Energy Metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Cell Death; Energy Metabolism; Glucose; Humans; Isoleucine; Leucine; Metabolomics; Myocytes, Cardiac; Valine | 2018 |
Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity.
Topics: Anemia; Animals; Bone Marrow; Cell Survival; Cells, Cultured; Culture Media; Diet; Erythrocyte Count; Fetal Blood; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Isoleucine; Leucine; Mice; Mice, Inbred C57BL; Radiation Chimera; Transplantation Conditioning; Valine | 2018 |
Metabolic reconstructions identify plant 3-methylglutaconyl-CoA hydratase that is crucial for branched-chain amino acid catabolism in mitochondria.
Topics: Amino Acids, Branched-Chain; Arabidopsis; Arabidopsis Proteins; Gene Knockdown Techniques; Hydro-Lyases; Isoleucine; Leucine; Metabolism; Mitochondria; Oryza; Plant Proteins; Sequence Alignment; Valine | 2018 |
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult | 2018 |
Optimal branched-chain amino acid ratio improves cell proliferation and protein metabolism of porcine enterocytesin in vivo and in vitro.
Topics: Amino Acid Transport Systems; Amino Acids, Branched-Chain; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cell Proliferation; Dietary Proteins; Ileum; Intestinal Mucosa; Isoleucine; Jejunum; Leucine; RNA, Messenger; Swine; Valine | 2018 |
Urinary Excretion of 2-Oxo Acids Is Greater in Rats with Streptozotocin-Induced Diabetes.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Energy Intake; Energy Metabolism; Hemiterpenes; Isoleucine; Keto Acids; Male; Rats, Wistar; Renal Elimination; Streptozocin; Valine; Weight Gain | 2018 |
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.
Topics: Aged; Alanine; Amino Acids; Area Under Curve; Biomarkers; Breath Tests; Case-Control Studies; Disease Progression; Exhalation; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Isoleucine; Leucine; Male; Middle Aged; ROC Curve; Spectrometry, Mass, Electrospray Ionization; Valine | 2019 |
Identification of the novel HLA-DRB5*02:21 allele in a Saudi individual.
Topics: Alleles; Exons; High-Throughput Nucleotide Sequencing; Histocompatibility Testing; HLA-DRB5 Chains; Humans; Isoleucine; Polymorphism, Single Nucleotide; Saudi Arabia; Valine | 2019 |
Can the Partial Peptide SIVSF of the β
Topics: Epinephrine; Humans; Isoleucine; Molecular Conformation; Neurotransmitter Agents; Peptides; Phenylalanine; Receptors, Adrenergic, beta-2; Serine; Valine | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Topics: Acetolactate Synthase; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli Proteins; Feedback, Physiological; Hydrogen Bonding; Isoleucine; Models, Molecular; Protein Binding; Protein Conformation; Valine | 2019 |
The influence of dietary leucine above recommendations and fixed ratios to isoleucine and valine on muscle protein synthesis and degradation pathways in broilers.
Topics: Animal Feed; Animals; Avian Proteins; Chickens; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Isoleucine; Leucine; Male; Muscle Proteins; Random Allocation; Signal Transduction; TOR Serine-Threonine Kinases; Valine | 2019 |
The
Topics: Acetolactate Synthase; Amino Acids, Branched-Chain; Aquatic Organisms; Escherichia coli; Gene Expression Regulation, Bacterial; Isoleucine; Leucine; Operon; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Valine; Vibrio alginolyticus | 2019 |
Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study.
Topics: Amino Acids; Female; Humans; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Patient Outcome Assessment; Proton Magnetic Resonance Spectroscopy; Pulmonary Disease, Chronic Obstructive; Smokers; Tryptophan; Valine | 2019 |
Substrate-product analogue inhibitors of isoleucine 2-epimerase from Lactobacillus buchneri by rational design.
Topics: Binding Sites; Biocatalysis; Drug Design; Enzyme Inhibitors; Glycine; Isoleucine; Lactobacillus; Models, Molecular; Molecular Conformation; Racemases and Epimerases; Substrate Specificity; Valine | 2019 |
Characteristics of amino acid profiles and incretin hormones in patients with gallstone disease: a pilot study.
Topics: Adult; Aged; Cholecystolithiasis; Diabetes Mellitus, Type 2; Female; Humans; Incretins; Isoleucine; Leucine; Lysine; Male; Metabolic Diseases; Middle Aged; Pilot Projects; Valine | 2019 |
The coordination of dietary valine and isoleucine on water holding capacity, pH value and protein solubility of fresh meat in finishing pigs.
Topics: Animal Feed; Animals; Body Composition; Diet; Hydrogen-Ion Concentration; Isoleucine; Male; Pork Meat; Random Allocation; Sarcomeres; Solubility; Sus scrofa; Valine; Water | 2020 |
PycnoRacer®, a fitness drink including Pycnogenol®, improves recovery and training in the Cooper test.
Topics: Adult; Arginine; Beverages; Dietary Supplements; Exercise; Exercise Test; Female; Flavonoids; Free Radicals; Humans; Isoleucine; Leucine; Male; Middle Aged; Oxidative Stress; Oxygen Consumption; Plant Extracts; Valine; Young Adult | 2019 |
Impact on Isoleucine and Valine Supplementation When Decreasing Use of Medical Food in the Nutritional Management of Methylmalonic Acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Dietary Proteins; Dietary Supplements; Enteral Nutrition; Female; Humans; Infant; Isoleucine; Male; Retrospective Studies; Treatment Outcome; Valine | 2020 |
Association between Dietary Habits and Physical Function in Brazilian and Italian Older Women.
Topics: Age Factors; Aged; Aged, 80 and over; Animal Proteins, Dietary; Body Mass Index; Brazil; Eating; Feeding Behavior; Female; Humans; Independent Living; Isoleucine; Italy; Leucine; Longevity; Nutritional Physiological Phenomena; Physical Functional Performance; Plant Proteins, Dietary; Valine | 2020 |
Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Dietary Supplements; Isoleucine; Leucine; Mice; Models, Animal; Muscle Fatigue; Muscle Proteins; Muscle, Skeletal; Performance-Enhancing Substances; Physical Conditioning, Animal; Proof of Concept Study; Valine | 2020 |
Potent cyclometallated Pd(II) antitumor complexes bearing α-amino acids: synthesis, structural characterization, DNA/BSA binding, cytotoxicity and molecular dynamics simulation.
Topics: Alanine; Amino Acids; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Survival; Coordination Complexes; DNA; Drug Development; Humans; Intercalating Agents; Isoleucine; Leucine; Molecular Conformation; Palladium; Phenylalanine; Protein Binding; Serum Albumin, Bovine; Structure-Activity Relationship; Valine | 2020 |
High leucine levels affecting valine and isoleucine recommendations in low-protein diets for broiler chickens.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet, Protein-Restricted; Dietary Supplements; Growth; Isoleucine; Leucine; Male; Random Allocation; Valine | 2020 |
A novel SNP of
Topics: Animals; Cattle; Genotype; Hot Temperature; Humidity; Isoleucine; Valine | 2022 |
The nuclear magnetic resonance metabolic profile: Impact of fasting status.
Topics: Adult; Algorithms; Cholesterol, LDL; Cholesterol, VLDL; Fasting; Female; Humans; Isoleucine; Magnetic Resonance Spectroscopy; Male; Postprandial Period; Prospective Studies; Risk Factors; Valine | 2021 |
3-(4-Carboxybenzoyl)quinoline-2-carboxaldehyde labeling for direct analysis of amino acids in plasma is not suitable for simultaneous quantification of tryptophan, tyrosine, valine, and isoleucine by CE/fluorescence.
Topics: Amino Acids; Animals; Isoleucine; Mice; Quinolines; Tryptophan; Tyrosine; Valine | 2021 |
Improving performance of finishing pigs with added valine, isoleucine, and tryptophan: validating a meta-analysis model.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Isoleucine; Meta-Analysis as Topic; Swine; Tryptophan; Valine; Zea mays | 2021 |
Residue Interaction Network Analysis Predicts a Val24-Ile31 Interaction May be Involved in Preventing Amyloid-Beta (1-42) Primary Nucleation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Databases, Protein; Humans; Hydrophobic and Hydrophilic Interactions; Isoleucine; Models, Molecular; Peptide Fragments; Protein Aggregation, Pathological; Protein Stability; Valine | 2021 |
Differences in gene expression of enzymes involved in branched-chain amino acid metabolism of abdominal subcutaneous adipose tissue between pregnant women with and without PCOS.
Topics: Adult; Amino Acids, Branched-Chain; Body Mass Index; Female; Gene Expression; Humans; Insulin Resistance; Isoleucine; Leucine; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Complications; Prognosis; Real-Time Polymerase Chain Reaction; RNA, Messenger; Subcutaneous Fat, Abdominal; Valine | 2021 |
The anti-obesity effects exerted by different fractions of Artemisia sphaerocephala Krasch polysaccharide in diet-induced obese mice.
Topics: Animals; Anti-Obesity Agents; Artemisia; Diet, High-Fat; Gastrointestinal Microbiome; Isoleucine; Leucine; Liver; Male; Mice; Mice, Inbred C57BL; Nitrogen; Obesity; Plant Extracts; Polysaccharides; Valine | 2021 |
Analgesic Activity of Jin Ling Zi Powder and Its Single Herbs: A Serum Metabonomics Study.
Topics: Analgesics; Animals; Aspirin; Biomarkers; Body Weight; Drugs, Chinese Herbal; Glycine; Glyoxylates; Inositol Phosphates; Isoleucine; Leucine; Metabolomics; Mice; Powders; RNA, Transfer; Serine; Threonine; Valine | 2022 |
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Topics: Adipose Tissue, White; Amino Acids, Branched-Chain; Animals; Body Mass Index; Diet; Energy Metabolism; Fibroblast Growth Factors; Humans; Isoleucine; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Protein Serine-Threonine Kinases; Uncoupling Protein 1; Valine | 2021 |
Comparative Effects of the Branched-Chain Amino Acids, Leucine, Isoleucine and Valine, on Gastric Emptying, Plasma Glucose, C-Peptide and Glucagon in Healthy Men.
Topics: Adult; Amino Acids, Branched-Chain; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Humans; Insulin; Isoleucine; Leucine; Male; Middle Aged; Postprandial Period; Valine; Whey Proteins; Young Adult | 2021 |
Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan.
Topics: Amino Acid Sequence; Bacterial Proteins; Crystallography, X-Ray; Escherichia coli; Isoleucine; Protein Domains; Protein Structure, Secondary; Repressor Proteins; Tryptophan; Valine; X-Ray Diffraction | 2021 |
Determination of modification degree of polysialylated therapeutic proteins using
Topics: Factor IX; Factor VIII; Isoleucine; Leucine; Models, Molecular; Molecular Structure; Protein Conformation; Proton Magnetic Resonance Spectroscopy; Recombinant Proteins; Sialic Acids; Valine | 2021 |
Effects of
Topics: Aged; Amino Acids, Branched-Chain; Cardiovascular Diseases; China; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Incidence; Isoleucine; Leucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Polymorphism, Single Nucleotide; Protein Phosphatase 2C; Valine | 2021 |
Backbone distortions in lactam-bridged helical peptides.
Topics: Circular Dichroism; Isoleucine; Lactams; Peptides; Peptides, Cyclic; Protein Conformation; Protein Structure, Secondary; Tyrosine; Valine | 2022 |
Acetolactate synthases regulatory subunit and catalytic subunit genes VdILVs are involved in BCAA biosynthesis, microscletotial and conidial formation and virulence in Verticillium dahliae.
Topics: Acetolactate Synthase; Acremonium; Amino Acids, Branched-Chain; Catalytic Domain; Fungal Proteins; Isoleucine; Lactates; Leucine; Plant Diseases; Spores, Fungal; Valine; Verticillium; Virulence | 2022 |
BrnQ-Type Branched-Chain Amino Acid Transporters Influence Bacillus anthracis Growth and Virulence.
Topics: Amino Acids, Branched-Chain; Animals; Anthrax; Bacillus anthracis; Bacterial Proteins; Cattle; Disease Models, Animal; Isoleucine; Mammals; Membrane Transport Proteins; Mice; Valine; Virulence | 2022 |
Transthyretin V142I Genetic Variant and Cardiac Remodeling, Injury, and Heart Failure Risk in Black Adults.
Topics: Adult; Heart Failure; Humans; Isoleucine; Middle Aged; Prealbumin; Troponin I; Valine; Ventricular Remodeling | 2022 |
Improvement of substrate recognition in branched-chain aminoacyl-tRNA synthetases from Escherichia coli under conditions of pyrophosphate amplification.
Topics: Adenosine; Amino Acids; Amino Acyl-tRNA Synthetases; Diphosphates; Escherichia coli; Isoleucine; Leucine; Leucine-tRNA Ligase; Magnesium; RNA, Transfer; Substrate Specificity; Valine; Valine-tRNA Ligase | 2022 |
Amino acid profile of skeletal muscle loss in type 2 diabetes: Results from a 7-year longitudinal study in asians.
Topics: Amino Acids; Amino Acids, Branched-Chain; Asian People; Diabetes Mellitus, Type 2; Humans; Isoleucine; Leucine; Longitudinal Studies; Muscle, Skeletal; Prospective Studies; Valine | 2022 |
An integrated metabonomics study to reveal the inhibitory effect and metabolism regulation of taurine on breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Choline; Female; Glutamic Acid; Histidine; Humans; Isoleucine; Lactic Acid; Leucine; Lung Neoplasms; Metabolomics; Mice; Taurine; Valine | 2022 |
A Mixture of Valine and Isoleucine Restores the Growth of Protein-Restricted Pigs Likely through Improved Gut Development, Hepatic IGF-1 Pathway, and Plasma Metabolomic Profile.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Diet, Protein-Restricted; Insulin-Like Growth Factor I; Isoleucine; Liver; Metabolomics; Swine; Valine | 2022 |
A multivariate Box-Behnken assessment of elevated branched-chain amino acid concentrations in reduced crude protein diets offered to male broiler chickens.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animal Feed; Animals; Chickens; Diet; Diet, Protein-Restricted; Isoleucine; Leucine; Male; Valine; Weight Gain | 2022 |
Effects of L-valine in layer diets containing 0.72% isoleucine.
Topics: Animal Feed; Animals; Chickens; Diet; Female; Isoleucine; Valine | 2022 |
Backbone and ILV side-chain NMR resonance assignments of the catalytic domain of human deubiquitinating enzyme USP7.
Topics: Catalytic Domain; Humans; Isoleucine; Leucine; Nuclear Magnetic Resonance, Biomolecular; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7; Ubiquitins; Valine | 2022 |
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine | 2022 |
Metabolic characterization of amniotic fluid of fetuses with isolated choroid plexus cyst.
Topics: Amniotic Fluid; Arginine; Aspartic Acid; Choroid Plexus; Citrulline; Coenzyme A; Cysts; Ethanolamines; Female; Glucose; Humans; Hydroxylysine; Isoleucine; Leucine; Pregnancy; Proline; Ultrasonography, Prenatal; Valine | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Dietary intake of branched-chain amino acids in relation to the risk of breast cancer.
Topics: Amino Acids, Branched-Chain; Breast Neoplasms; Case-Control Studies; Eating; Female; Humans; Iran; Isoleucine; Leucine; Risk Factors; Valine | 2022 |
Ultra-HPLC-MS pseudo-targeted metabolomic profiling reveals metabolites and associated metabolic pathway alterations in Asian plum (
Topics: Alkaloids; Chromatography, High Pressure Liquid; Fruit; Glucosinolates; Isoleucine; Isoquinolines; Leucine; Mass Spectrometry; Metabolic Networks and Pathways; Proanthocyanidins; Prunus domestica; Valine | 2022 |
Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.
Topics: Amino Acids, Branched-Chain; Animals; Diglycerides; Hyperinsulinism; Inflammation; Isoleucine; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Valine | 2022 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Animal; Epilepsy; Glucose; Glutamates; Isoleucine; Ketone Bodies; Lactates; Leucine; Pentylenetetrazole; Pyruvates; Rats; Seizures; Succinates; Valine | 2022 |
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan.
Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine | 2022 |
Effects of serum branched-chain amino acids on nonalcoholic fatty liver disease and subsequent cardiovascular disease.
Topics: Amino Acids, Branched-Chain; Cardiovascular Diseases; Cohort Studies; Humans; Isoleucine; Leucine; Non-alcoholic Fatty Liver Disease; Valine | 2022 |
Prospective Association Between Plasma Amino Acids and Multimorbidity in Older Adults.
Topics: Aged; Amino Acids; Chronic Disease; Female; Glutamine; Humans; Isoleucine; Male; Multimorbidity; Valine | 2023 |
Transcriptome Analysis Reveals the Algicidal Mechanism of
Topics: Bacillus; Brevibacillus; Gene Expression Profiling; Harmful Algal Bloom; Isoleucine; Leucine; Metabolic Networks and Pathways; Microcystis; Valine | 2022 |
Functional significance of the rare rs35667974
Topics: Arthritis, Psoriatic; Autoantigens; Autoimmune Diseases; Chemokines; DEAD-box RNA Helicases; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Interferon-Induced Helicase, IFIH1; Interferons; Isoleucine; Polymorphism, Genetic; RNA, Viral; Valine | 2022 |
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine | 2022 |
Identifying a metabolomics profile associated with masked hypertension in two independent cohorts: Data from the African-PREDICT and SABPA studies.
Topics: Amino Acids; Carnitine; Humans; Isoleucine; Leucine; Masked Hypertension; Metabolomics; Methionine; Phenylalanine; Valine | 2022 |
Phenotype microarray analysis reveals the biotransformation of Fusarium oxysporum f.sp. lycopersici influenced by Bacillus subtilis PBE-8 metabolites.
Topics: Alanine; Ammonia; Antifungal Agents; Arginine; Aspartic Acid; Bacillus subtilis; Biotransformation; Carbon; Fusarium; Glutamic Acid; Glutamine; Glycine; Isoleucine; Leucine; Linoleic Acids; Linolenic Acids; Microarray Analysis; Nitrogen; Phenotype; Plant Diseases; Proline; RNA, Transfer; Solanum lycopersicum; Valine | 2022 |
Integrated physiologic and proteomic analysis of Stropharia rugosoannulata mycelia in response to Cd stress.
Topics: Agaricales; Antioxidants; Cadmium; Glutathione Disulfide; Humans; Isoleucine; Leucine; Proteome; Proteomics; Reactive Oxygen Species; Soil; Superoxide Dismutase; Tyrosine; Valine | 2023 |
Influence of nitrogen sources on the tolerance of Lacticaseibacillus rhamnosus to heat stress and oxidative stress.
Topics: Glutamates; Heat-Shock Response; Histidine; Isoleucine; Lacticaseibacillus rhamnosus; Nitrogen; Oxidative Stress; Phenylalanine; Powders; Probiotics; Tryptophan; Valine | 2022 |
Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells.
Topics: Amino Acids, Branched-Chain; Animals; Caseins; Epithelial Cells; Female; Isoleucine; Lactation; Leucine; Mammary Glands, Animal; Proteasome Endopeptidase Complex; Proteolysis; Swine; TOR Serine-Threonine Kinases; Ubiquitin; Valine | 2022 |
Comparative analysis of sugar, acid, and volatile compounds in CPPU-treated and honeybee-pollinated melon fruits during different developmental stages.
Topics: Animals; Bees; Citric Acid; Cucurbitaceae; Fruit; Isoleucine; Leucine; Methionine; Odorants; Phenylalanine; Plant Growth Regulators; Sugars; Valine; Volatile Organic Compounds | 2023 |
Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach.
Topics: Amino Acids, Diamino; Coenzyme A; Cyanobacteria Toxins; Diatoms; Humans; Isoleucine; Leucine; Neurotoxins; Nitrogen; SNARE Proteins; Tandem Mass Spectrometry; Transcriptome; Valine | 2023 |
An accurate strategy for pointing the key biocatalytic sites of bre2691A protein for modification of the brevilaterin from Brevibacillus laterosporus.
Topics: Amino Acids; Anti-Bacterial Agents; Anti-Infective Agents; Bacillus; Bacterial Proteins; Biocatalysis; Brevibacillus; Isoleucine; Leucine; Lipopeptides; Methionine; Molecular Docking Simulation; Valine | 2022 |
Toxicity effects of chlorantraniliprole in zebrafish (Danio rerio) involving in liver function and metabolic phenotype.
Topics: Alanine; Animals; Aspartic Acid; Glutamic Acid; Glutamine; Insecticides; Isoleucine; Leucine; Liver; Malondialdehyde; ortho-Aminobenzoates; Phenotype; Valine; Water Pollutants, Chemical; Zebrafish | 2022 |
Quantification of Branched-Chain Amino Acids in Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Topics: Amino Acids; Amino Acids, Branched-Chain; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methanol; Nitrogen Isotopes; Oxidoreductases; Tandem Mass Spectrometry; Valine | 2022 |
NMR-Based Metabolomic Analysis for the Effects of Trimethylamine N-Oxide Treatment on C2C12 Myoblasts under Oxidative Stress.
Topics: Alanine; Catalase; Diabetes Mellitus, Type 2; Glycine; Histidine; Humans; Hydrogen Peroxide; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Malondialdehyde; Methylamines; Myoblasts; Oxidative Stress; Phenylalanine; Phosphorylcholine; Superoxide Dismutase; Threonine; Valine | 2022 |
Chemical Composition Assessment of Structural Parts (Seeds, Peel, Pulp) of
Topics: Arginine; Aspartic Acid; Fatty Acids; Fatty Acids, Unsaturated; Fruit; Humans; Isoleucine; Linoleic Acid; Oleic Acid; Phenylalanine; Physalis; Plant Oils; Prospective Studies; Seeds; Threonine; Tocopherols; Valine; Vitamins | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
[Cell metabolomics study of ginkgo flavone aglycone combined with doxorubicin against liver cancer in synergy].
Topics: Arginine; beta-Alanine; Doxorubicin; Flavones; Ginkgo biloba; Glutathione; Humans; Isoleucine; Leucine; Liver Neoplasms; Metabolomics; Phenylalanine; Proline; Tandem Mass Spectrometry; Tyrosine; Valine | 2022 |
Understanding the interactive effects of dietary leucine with isoleucine and valine in the modern commercial broiler.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animal Feed; Animals; Chickens; Diet; Isoleucine; Leucine; Male; Valine; Weight Gain | 2022 |
Modified Stranski-Krastanov Growth of Amino Acid Arrays toward Piezoelectric Energy Harvesting.
Topics: Amino Acids; Electric Power Supplies; Isoleucine; Leucine; Powders; Valine | 2022 |
Topics: Agaricales; Animals; Antioxidants; Arginine; Biomarkers; Diet, High-Fat; Fucose; Galactose; Glucose; Glycerides; Glycerol; Isoleucine; Leucine; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Mannose; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phospholipids; Polysaccharides; Proline; Spectroscopy, Fourier Transform Infrared; Steroids; Valine; Xylose | 2022 |
Urinary Metabolomics Study on the Protective Role of Cocoa in Zucker Diabetic Rats via
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Cacao; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonoids; Glycated Hemoglobin; Isoleucine; Ketone Bodies; Leucine; Male; Metabolomics; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Zucker; Valine | 2022 |
Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study.
Topics: Anxiety Disorders; Bile Acids and Salts; Genome-Wide Association Study; Humans; Isoleucine; Leucine; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide; Valine | 2022 |
Comparison of amino acid digestibility and its additivity determined with slaughter or cecectomy method for yellow-feather chicken.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Chickens; Diet; Digestion; Feathers; Glutamic Acid; Glycine; Glycine max; Histidine; Ileum; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Valine; Zea mays | 2022 |
Basement-Membrane-Related Gene Signature Predicts Prognosis in WHO Grade II/III Gliomas.
Topics: Basement Membrane; Glioma; Glycosphingolipids; Humans; Isoleucine; Leucine; Prognosis; Valine; World Health Organization | 2022 |
Association between Branched-Chain Amino Acid Intake and Physical Function among Chinese Community-Dwelling Elderly Residents.
Topics: Aged; Amino Acids, Branched-Chain; China; Female; Hand Strength; Humans; Independent Living; Isoleucine; Leucine; Male; Risk Factors; Valine | 2022 |
A portable device as a paper test strip platform with smartphone application for detection of branched-chain amino acids in edible insects.
Topics: Amino Acids, Branched-Chain; Animals; Edible Insects; Isoleucine; Leucine; Metal Nanoparticles; Silver; Smartphone; Valine | 2023 |
Taxonomic and Metagenomic Analyses Define the Development of the Microbiota in the Chick.
Topics: Amino Acids, Branched-Chain; Animals; Cecum; Chickens; Isoleucine; Microbiota; Poultry Diseases; Salmonella Infections, Animal; Salmonella typhimurium; Valine | 2023 |
Effect of Isoleucine and Added Valine on Performance, Nutrients Digestibility and Gut Microbiota Composition of Pigs Fed with Very Low Protein Diets.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Diet, Protein-Restricted; Dietary Supplements; Digestion; Isoleucine; Swine; Valine | 2022 |
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.
Topics: Amino Acids, Branched-Chain; Atherosclerosis; Cross-Sectional Studies; Diabetes Mellitus; Humans; Isoleucine; Mendelian Randomization Analysis; Obesity; Valine | 2022 |
The Aging Process: A Metabolomics Perspective.
Topics: Adult; Aged; Aging; Aspartic Acid; Biomarkers; Female; Humans; Isoleucine; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Ornithine; Urea; Valine; Young Adult | 2022 |
Serum metabolic profiling of rats infected with
Topics: Amino Acids; Animals; Biomarkers; Chromatography, Liquid; Clonorchiasis; Clonorchis sinensis; Glutamates; Glutamine; Isoleucine; Leucine; Metabolomics; Rats; Tandem Mass Spectrometry; Threonine; Valine | 2022 |
Integration of proteomic and metabolomic analyses: New insights for mapping informal workers exposed to potentially toxic elements.
Topics: Brazil; Humans; Isoleucine; Lead; Leucine; Proteomics; Valine | 2022 |
A Model for the Rapid Assessment of Solution Structures for 24-Atom Macrocycles: The Impact of β-Branched Amino Acids on Conformation.
Topics: Amino Acids; Isoleucine; Molecular Conformation; Threonine; Valine | 2023 |
Dietary Intake and Circulating Amino Acid Concentrations in Relation with Bone Metabolism Markers in Children Following Vegetarian and Omnivorous Diets.
Topics: Amino Acids; Child; Diet; Diet, Vegetarian; Eating; Humans; Isoleucine; Leucine; Lysine; Nutritional Status; Valine; Vegetarians | 2023 |
Association of Circulating Branched-Chain Amino Acids with Cardiovascular Diseases: A Mendelian Randomization Study.
Topics: Amino Acids, Branched-Chain; Cardiovascular Diseases; Cerebral Hemorrhage; Cohort Studies; Genome-Wide Association Study; Humans; Isoleucine; Leucine; Mendelian Randomization Analysis; Peripheral Arterial Disease; Polymorphism, Single Nucleotide; Stroke; Valine | 2023 |
[Dietary consumption of branched-chain amino acids among Chinese middle-aged and elderly population aged 50 and over in 2015].
Topics: Aged; Amino Acids, Branched-Chain; Animals; China; Female; Humans; Isoleucine; Leucine; Male; Valine; Vegetables | 2023 |
Potential role of plasma branched-chain amino acids in the differential diagnosis of acute cerebral venous thrombosis.
Topics: Amino Acids, Branched-Chain; Biomarkers; Diagnosis, Differential; Humans; Isoleucine; Leucine; Valine; Venous Thrombosis | 2023 |
Natural Clearance of Chlamydia trachomatis Infection Is Associated With Distinct Differences in Cervicovaginal Metabolites.
Topics: Amino Acids; Chlamydia Infections; Chlamydia trachomatis; Female; Humans; Interferon-gamma; Isoleucine; Leucine; Tryptophan; Valine | 2023 |
Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures, and Bone Mineral Density of the Hip and Spine.
Topics: Aged; Amino Acids, Branched-Chain; Bone Density; Cross-Sectional Studies; Female; Fractures, Bone; Hip Fractures; Humans; Isoleucine; Leucine; Male; Valine | 2023 |
Impact of non-proteinogenic amino acid norvaline and proteinogenic valine misincorporation on a secondary structure of a model peptide.
Topics: Amino Acids; Escherichia coli; Isoleucine; Peptides; Proteome; Valine | 2023 |
Acyl-CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Acyl-CoA Dehydrogenase; Carnitine; HEK293 Cells; Humans; Isoleucine; Propionic Acidemia; Valine | 2023 |
Plasma amino acids by age and gender in Hangzhou, Eastern China.
Topics: Amino Acids; Arginine; Chromatography, Liquid; Female; Glycine; Humans; Isoleucine; Leucine; Male; Phenylalanine; Proline; Tandem Mass Spectrometry; Valine | 2023 |
Production improvement of FK506 in Streptomyces tsukubaensis by metabolic engineering strategy.
Topics: Immunosuppressive Agents; Isoleucine; Metabolic Engineering; Tacrolimus; Valine | 2023 |
Branched-chain amino acid biosynthesis in fungi.
Topics: Amino Acids, Branched-Chain; Isoleucine; Leucine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators; Transcription Factors; Valine | 2023 |
Sex-Specific Correlation Analysis of Branched-Chain Amino Acids in Dietary Intakes and Plasma among Chinese Adults.
Topics: Amino Acids, Branched-Chain; Case-Control Studies; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; East Asian People; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Prospective Studies; Valine | 2023 |
Heat Capacities of
Topics: Alanine; Amides; Amino Acids; Glycine; Hot Temperature; Isoleucine; Leucine; Valine | 2023 |
Light effects on Lasiodiplodia theobromae metabolome cultured in vitro.
Topics: Betaine; Choline; Isoleucine; Leucine; Metabolome; Metabolomics; Phosphorylcholine; Valine | 2023 |
Does slaughter age affect amino acids and fatty acids profiles and health and nutritional values of male and female ROSS 308 broiler chicken breast muscle?
Topics: Amino Acids; Animal Feed; Animals; Chickens; Fatty Acids; Female; Glutamates; Histidine; Isoleucine; Leucine; Male; Meat; Muscles; Nutritive Value; Valine | 2023 |
Study on the underlying mechanism of Poria in intervention of arrhythmia zebrafish by integrating metabolomics and network pharmacology.
Topics: Animals; Arrhythmias, Cardiac; Drugs, Chinese Herbal; Isoleucine; Leucine; Metabolomics; Molecular Docking Simulation; Network Pharmacology; Poria; Valine; Water; Zebrafish | 2024 |
Association of plasma branched-chain amino acid with multiple cancers: A mendelian randomization analysis.
Topics: Amino Acids, Branched-Chain; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Genome-Wide Association Study; Humans; Isoleucine; Leucine; Lung Neoplasms; Mendelian Randomization Analysis; Valine | 2023 |
NMR analysis seeking for cognitive decline and dementia metabolic markers in plasma from aged individuals.
Topics: Acetone; Aged; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Glutamates; Histidine; Humans; Isobutyrates; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Tyrosine; Valine | 2024 |
Maternal glycemic status during pregnancy and mid-childhood plasma amino acid profiles: findings from a multi-ethnic Asian birth cohort.
Topics: Birth Cohort; Body Mass Index; Cardiovascular Diseases; Child; Diabetes, Gestational; Female; Glucose; Histidine; Humans; Hyperglycemia; Isoleucine; Leucine; Pregnancy; Valine | 2023 |