isoleucine and heme

isoleucine has been researched along with heme in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's6 (20.69)18.2507
2000's12 (41.38)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braunitzer, G; Liljeqvist, G; Paléus, S1
Padmanaban, G; Surolia, N1
Cutler, RL; Davies, AM; Greenwood, C; Mauk, AG; Moore, GR; Pielak, GJ; Smith, M; Thurgood, AG; Williamson, DJ1
Chui, LC; Gabuzda, TG; Lewis, HB; Silver, RK1
Margoliash, E; Putterman, GJ; Sherman, F1
Fisher, JM; Mizuno, S; Rabinovitz, M1
Fisher, JM; Freedman, ML; Maxwell, CR; Rabinovitz, M1
Barlow, GH; Campbell, LL; Drucker, H; Margoliash, E; Trousil, EB1
Amit, N; Formanek, H1
Honig, GR; Mason, RG; Rowan, BQ1
Koshy, TI; Luntz, TL; Margoliash, E; Sanishvili, R; Schejter, A; Vig, I1
Bardakdjian, J; Galacteros, F; Harousseau, JL; Kister, J; M'Rad, A; Milpied, N; Promé, D; Rapp, MJ; Riou, J; Wajcman, H1
Brandt, U; Meunier, B; Ortwein, C; Rich, PR1
Dou, Y; Gooding, EA; Hochstrasser, RM; Ikeda-Saito, M; Kholodenko, Y1
Morgan, JE; Puustinen, A; Riistama, S; Verkhovsky, MI; Wikström, M1
Iizuka, T; Mukai, M; Nakamura, H; Nakamura, K; Shiro, Y1
Ishikawa, H; Ishimori, K; Morishima, I; Takahashi, S; Uchida, T1
Brunori, M; Draghi, F; Gibson, QH; Miele, AE; Olson, JS; Travaglini-Allocatelli, C; Vallone, B1
Kerby, RL; Roberts, GP; Youn, H1
Crane, BR; Pant, K; Sharma, M; Stuehr, DJ; Wang, ZQ; Wei, CC1
Ishikawa, H; Ishimori, K; Morishima, I; Takahashi, S1
O'Connor, SE; Vaillancourt, FH; Vosburg, DA; Walsh, CT; Yeh, E1
Fujii, H; Nakamura, H; Shiro, Y; Tanaka, A1
Car, R; De Angelis, F; Jarzecki, AA; Spiro, TG1
Davydov, R; García-Serres, R; Hoffman, BM; Huynh, BH; Kim, SH; Lippard, SJ; McCormick, MS; Murray, LJ; Naik, SG1
Ismail, R; Ong, CE; Pan, Y; Singh, R; Teh, LK; Ting, JG1
Carpena, X; Chelikani, P; Donald, LJ; Fita, I; Jha, V; Loewen, PC; Louis, S1
Berry, RE; Shokhirev, NV; Shokhireva, TK; Walker, FA; Zhang, H1
Besley, NA; Hirst, JD; Suess, CJ1

Other Studies

29 other study(ies) available for isoleucine and heme

ArticleYear
[Hemoglobins. XXVII. The amino acid sequence of hemoglobin III from Myxine glutinosa L. A new hemecomplex: E7 glutamine, E11 isoleucine].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1979, Volume: 360, Issue:2

    Topics: Amino Acid Sequence; Animals; Fishes; Glutamine; Heme; Hemoglobins; Isoleucine; Peptide Fragments

1979
de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite.
    Biochemical and biophysical research communications, 1992, Sep-16, Volume: 187, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Glutamates; Glutamic Acid; Heme; Heptanoates; Isoleucine; Plasmodium falciparum; Porphobilinogen Synthase; Protein Biosynthesis

1992
Change in charge of an unvaried heme contact residue does not cause a major change of conformation in cytochrome c.
    FEBS letters, 1991, Jun-24, Volume: 284, Issue:2

    Topics: Alanine; Arginine; Cytochrome c Group; Electrochemistry; Heme; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Mutagenesis; Protein Conformation; Saccharomyces cerevisiae

1991
The formation of foetal and adult haemoglobin in cell cultures of neonatal calf marrow.
    British journal of haematology, 1970, Volume: 19, Issue:5

    Topics: Animals; Animals, Newborn; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cattle; Culture Techniques; Erythropoietin; Fetal Hemoglobin; gamma-Globulins; Heme; Hemoglobins; Iron; Iron Isotopes; Isoleucine; Leucine; Stimulation, Chemical

1970
Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.
    The Journal of biological chemistry, 1974, Jul-10, Volume: 249, Issue:13

    Topics: Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Chymotrypsin; Cytochrome c Group; Electrophoresis; Genes; Heme; Hydrolysis; Isoleucine; Mutation; Peptides; Proline; RNA, Messenger; Saccharomyces cerevisiae; Serine; Threonine; Ultraviolet Rays

1974
Hemin control of globin synthesis: action of an inhibitor formed in the absence of hemin on the reticulocyte cell-free system and its reversal by a ribosomal factor.
    Biochimica et biophysica acta, 1972, Jul-31, Volume: 272, Issue:4

    Topics: Animals; Blood Proteins; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Globins; Heme; Histidine; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; Trypsin

1972
Translational control in hemoglobin syntheskis.
    Cold Spring Harbor symposia on quantitative biology, 1969, Volume: 34

    Topics: Animals; Blood Proteins; Cell-Free System; Depression, Chemical; Deuterium; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Iron Isotopes; Isoleucine; Leucine; Liver; Metabolism; Models, Biological; Models, Structural; Peptide Biosynthesis; Porphyrins; Pyridines; Rabbits; Reticulocytes; Ribosomes; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Spectrophotometry; Stimulation, Chemical; Temperature; Threonine; Ultraviolet Rays

1969
Amino acid composition, heme content, and molecular weight of cytochrome c3 of Desulfovibrio desulfuricans and Desulfovibrio vulgaris.
    Biochemistry, 1970, Mar-31, Volume: 9, Issue:7

    Topics: Amino Acids; Arginine; Aspartic Acid; Cytochromes; Desulfovibrio; Glutamates; Heme; Hydrogen-Ion Concentration; Isoleucine; Molecular Weight

1970
[The oxygen affinity of Chironomus thummi erythrocruorins].
    European journal of biochemistry, 1970, Volume: 15, Issue:1

    Topics: Animals; Blood Proteins; Cetacea; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Diptera; Heme; Histidine; Isoleucine; Myoglobin; Oxygen; Phenylalanine; X-Ray Diffraction

1970
Unequal synthesis of complementary globin chains of human fetal hemoglobin by the effect of L-O-methylthreonine.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Blood Proteins; Carbon Isotopes; Chromatography, Gel; Complement System Proteins; Depression, Chemical; Erythroblastosis, Fetal; Female; Fetal Hemoglobin; Globins; Heme; Hemolysis; Humans; In Vitro Techniques; Infant, Newborn; Isoleucine; Leucine; Lysine; Peptide Biosynthesis; Pregnancy; Solubility; Thalassemia; Threonine

1969
Effects of mutating Asn-52 to isoleucine on the haem-linked properties of cytochrome c.
    The Biochemical journal, 1994, Aug-15, Volume: 302 ( Pt 1)

    Topics: Animals; Asparagine; Cyanides; Cytochrome c Group; Heme; Hydrogen-Ion Concentration; Ions; Isoleucine; Mutagenesis, Site-Directed; Oxidation-Reduction; Rats; Saccharomyces cerevisiae

1994
Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.
    American journal of hematology, 1993, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Amino Acids; Chromatography, High Pressure Liquid; Genetic Variation; Heme; Hemoglobins, Abnormal; Humans; Isoleucine; Leucine; Male; Mass Spectrometry; Middle Aged; Oxygen; Phenylalanine; Polycythemia

1993
Effects of mutation of residue I67 on redox-linked protonation processes in yeast cytochrome c oxidase.
    The Biochemical journal, 1998, Mar-15, Volume: 330 ( Pt 3)

    Topics: Asparagine; Electron Transport Complex IV; Glutamic Acid; Heme; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Macromolecular Substances; Models, Molecular; Oxidation-Reduction; Point Mutation; Potentiometry; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae

1998
Heme protein dynamics revealed by geminate nitric oxide recombination in mutants of iron and cobalt myoglobin.
    Biochemistry, 1999, May-04, Volume: 38, Issue:18

    Topics: Amino Acid Substitution; Animals; Cobalt; Heme; Iron; Isoleucine; Mutagenesis, Site-Directed; Myoglobin; Nitric Oxide; Phenylalanine; Thermodynamics; Whales

1999
Binding of O(2) and its reduction are both retarded by replacement of valine 279 by isoleucine in cytochrome c oxidase from Paracoccus denitrificans.
    Biochemistry, 2000, May-30, Volume: 39, Issue:21

    Topics: Amino Acid Substitution; Conserved Sequence; Cytochrome b Group; Cytochromes; Electron Transport Complex IV; Escherichia coli; Escherichia coli Proteins; Heme; Isoleucine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Paracoccus denitrificans; Photolysis; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Valine

2000
Roles of Ile209 and Ile210 on the heme pocket structure and regulation of histidine kinase activity of oxygen sensor FixL from Rhizobium meliloti.
    Biochemistry, 2000, Nov-14, Volume: 39, Issue:45

    Topics: Bacterial Proteins; Carbon Monoxide; Enzyme Activation; Ferric Compounds; Heme; Hemeproteins; Histidine; Histidine Kinase; Isoleucine; Mutagenesis, Site-Directed; Oxygen; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinases; Sinorhizobium meliloti; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tryptophan

2000
Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding.
    Biophysical journal, 2001, Volume: 80, Issue:3

    Topics: Alanine; Amino Acid Substitution; Binding Sites; Heme; Humans; Isoleucine; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Phenylalanine; Protein Conformation; Recombinant Proteins; Thermodynamics; Valine

2001
Controlling ligand binding in myoglobin by mutagenesis.
    The Journal of biological chemistry, 2002, Mar-01, Volume: 277, Issue:9

    Topics: Amino Acid Motifs; Animals; Ascaris suum; Crystallography, X-Ray; Heme; Hemoglobins; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Ligands; Models, Biological; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Myoglobin; Nitric Oxide; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombination, Genetic; Time Factors

2002
The role of the hydrophobic distal heme pocket of CooA in ligand sensing and response.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Bacterial Proteins; Cyanides; Dose-Response Relationship, Drug; Heme; Hemeproteins; Imidazoles; Isoleucine; Leucine; Ligands; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rhodospirillum rubrum; Trans-Activators; Transcriptional Activation

2003
A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles.
    The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18

    Topics: Amino Acid Substitution; Animals; Bacillus subtilis; Bacterial Proteins; Binding Sites; Catalysis; Conserved Sequence; Heme; Iron; Isoleucine; Kinetics; Mice; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Valine

2004
Steric effects of isoleucine 107 on heme reorientation reaction in human myoglobin.
    Biochemical and biophysical research communications, 2004, Nov-19, Volume: 324, Issue:3

    Topics: Biochemistry; Heme; Hemin; Histidine; Humans; Isoleucine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Myoglobin; Phenylalanine; Proteins; Spectrophotometry; Spectrum Analysis, Raman; Stereoisomerism; X-Rays

2004
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis.
    Nature, 2005, Aug-25, Volume: 436, Issue:7054

    Topics: Acyltransferases; Amino Acids; Bacterial Proteins; Catalysis; Chlorine; Enzymes; Heme; Indenes; Iron; Isoleucine; Pseudomonas syringae; Valine

2005
Roles of the heme distal residues of FixL in O2 sensing: a single convergent structure of the heme moiety is relevant to the downregulation of kinase activity.
    Biochemistry, 2006, Feb-28, Volume: 45, Issue:8

    Topics: Arginine; Bacterial Proteins; Binding Sites; Cyanides; Down-Regulation; Heme; Hemeproteins; Histidine Kinase; Hydrogen Bonding; Imidazoles; Iron; Isoleucine; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mutation; Oxidation-Reduction; Oxygen; Phosphorylation; Protein Conformation; Protein Kinases; Sinorhizobium meliloti; Spectrum Analysis, Raman

2006
Quantum chemical evaluation of protein control over heme ligation: CO/O2 discrimination in myoglobin.
    The journal of physical chemistry. B, 2005, Feb-24, Volume: 109, Issue:7

    Topics: Animals; Binding Sites; Carbon; Carbon Monoxide; Heme; Histidine; Isoleucine; Models, Molecular; Molecular Conformation; Myoglobin; Oxygen; Photochemistry; Protein Binding; Quantum Theory; Software

2005
Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase.
    Biochemistry, 2007, Dec-25, Volume: 46, Issue:51

    Topics: Binding Sites; Crystallography, X-Ray; Enzyme Activation; Heme; Hydrogen-Ion Concentration; Iron; Isoleucine; Kinetics; Models, Molecular; Mutation; Oxidation-Reduction; Oxygen; Oxygenases; Phenol; Protein Structure, Tertiary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrum Analysis; Substrate Specificity; Tryptophan

2007
Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity.
    Drug metabolism and pharmacokinetics, 2008, Volume: 23, Issue:3

    Topics: Amino Acid Substitution; Animals; Aryl Hydrocarbon Hydroxylases; Catalysis; Catalytic Domain; Cloning, Molecular; Cytochrome P-450 CYP2C8; DNA Primers; Endopeptidase K; Enzyme Stability; Escherichia coli; Heme; Humans; Isoleucine; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Paclitaxel; Polymorphism, Genetic; Protein Folding; Rats; Substrate Specificity; Tolbutamide

2008
Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli.
    Biochemistry, 2011, Mar-29, Volume: 50, Issue:12

    Topics: Biocatalysis; Catalase; Escherichia coli; Heme; Isoleucine; Models, Molecular; Mutation; Protein Binding; Protein Conformation; X-Rays

2011
NMR studies of nitrophorin distal pocket side chain effects on the heme orientation and seating of NP2 as compared to NP1.
    Journal of inorganic biochemistry, 2011, Volume: 105, Issue:9

    Topics: Amino Acid Sequence; Animals; Anticoagulants; Cloning, Molecular; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Hemeproteins; Insect Vectors; Isoleucine; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Recombinant Proteins; Rhodnius; Salivary Proteins and Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transformation, Bacterial

2011
Quantum chemical calculations of tryptophan → heme electron and excitation energy transfer rates in myoglobin.
    Journal of computational chemistry, 2017, 06-30, Volume: 38, Issue:17

    Topics: Density Functional Theory; Electrons; Energy Transfer; Heme; Hydrogen Bonding; Isoleucine; Microscopy; Myoglobin; Protein Conformation; Spectrophotometry, Ultraviolet; Tryptophan; Valine

2017