isoleucine and deuterium

isoleucine has been researched along with deuterium in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's4 (12.90)18.2507
2000's11 (35.48)29.6817
2010's7 (22.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoerr, RA; Marks, L; Pelletier, V; Wagner, DA; Young, VR1
Johns, RB; Looney, FD; Whelan, DJ1
Deslauriers, R; Smith, IC; Walter, R1
Cunnion, SO; Santi, DV1
Bradbury, AF; Burgen, AS; Feeney, J; Roberts, GC; Smyth, DG1
Fisher, JM; Freedman, ML; Maxwell, CR; Rabinovitz, M1
Dugas, H; Kaplan, H; Symonds, VB; Whitaker, DR1
MacDonald, JC1
Chibata, I; Crout, DH; Gregorio, MV; Kisumi, M; Komatsubara, S; Müller, US1
Biemann, K; Herlihy, WC; Kidwell, D; Meeusen, B1
Overman, SA; Thomas, GJ1
Ferretti, JA; Gawrisch, K; Koenig, BW1
Gardner, KH; Goto, NK; Kay, LE; Mueller, GA; Willis, RC1
Brivet, M; Roe, CR; Roe, DS; Sweetman, L1
Chin, JK; Klinman, JP1
Angeletti, RH; Grubmeyer, C; Nieves, E; Schramm, VL; Shi, W; Wang, F1
Daniels, BV; Forsyth, VT; Lawson, CL; Myles, DA1
Kay, LE; Tugarinov, V2
Dyson, HJ; Schnell, JR; Wright, PE1
Bodenhausen, G; Dittmer, J1
Hewlins, MJ; John, RA; Markova, M; Peneff, C; Schirmer, T1
Clore, GM; Tang, C1
Ayala, I; Boisbouvier, J; Gans, P; Sounier, R; Usé, N1
Kay, LE; Religa, TL1
Atreya, HS; D'Silva, P; Jaipuria, G; Thakur, A1
Kay, LE; Ruschak, AM; Velyvis, A1
East, K; Hammel, SC; Rose, MR; Shahrestani, P; Shaka, AJ1
Dunkelberger, EB; Woys, AM; Zanni, MT1
Miyazawa-Onami, M; Shimada, I; Sugiki, T; Takahashi, H; Takano, T; Takeuchi, K1
Akabayov, SR; Anglister, J; Arshava, B; Kessler, N; Moseri, A; Naider, F; Srivastava, G1

Trials

1 trial(s) available for isoleucine and deuterium

ArticleYear
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:2

    Topics: Adult; Carbon Isotopes; Deuterium; Fasting; Food; Humans; Infusions, Intravenous; Isoleucine; Kinetics; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Valine

1991

Other Studies

30 other study(ies) available for isoleucine and deuterium

ArticleYear
Photochemistry of biological molecules. I. Photolysis of amino acids in the solid state.
    Biochimica et biophysica acta, 1967, Oct-23, Volume: 147, Issue:2

    Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Crystallization; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Isoleucine; Radiation; Radiation Effects; Ultraviolet Rays; Valerates; Valine

1967
The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin-lattice relaxation times.
    Biochemical and biophysical research communications, 1974, May-07, Volume: 58, Issue:1

    Topics: Carbon Isotopes; Computers; Deuterium; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Fourier Analysis; Glucosamine; Isoleucine; Leucine; Molecular Conformation; Oxytocin; Time Factors; Tyrosine

1974
Macromolecular affinity labeling agents. Reaction of N-bromoacetylisoleucyl transfer ribonucleic acid with isoleucyl transfer ribonucleic acid synthetase.
    Biochemistry, 1974, Jan-29, Volume: 13, Issue:3

    Topics: Acetates; Alkylation; Amino Acyl-tRNA Synthetases; Binding Sites; Binding, Competitive; Bromine; Chemical Phenomena; Chemistry; Chromatography, Gel; Deuterium; Escherichia coli; Isoleucine; Isotope Labeling; Macromolecular Substances; Mercaptoethanol; Protein Binding; RNA, Transfer; Structure-Activity Relationship; Tritium; Urea

1974
Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H- and 15N-substituted molecules.
    FEBS letters, 1974, Jun-01, Volume: 42, Issue:2

    Topics: Animals; Biological Assay; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Deuterium; Female; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Oxytocin; Protein Conformation; Rats; Structure-Activity Relationship; Tyrosine; Uterus

1974
Translational control in hemoglobin syntheskis.
    Cold Spring Harbor symposia on quantitative biology, 1969, Volume: 34

    Topics: Animals; Blood Proteins; Cell-Free System; Depression, Chemical; Deuterium; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Iron Isotopes; Isoleucine; Leucine; Liver; Metabolism; Models, Biological; Models, Structural; Peptide Biosynthesis; Porphyrins; Pyridines; Rabbits; Reticulocytes; Ribosomes; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Spectrophotometry; Stimulation, Chemical; Temperature; Threonine; Ultraviolet Rays

1969
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:6

    Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine

1970
Biosynthesis of compounds similar to aspergillic acid.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:10

    Topics: Amino Acids; Aspergillus; Chromatography; Culture Media; Deuterium; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Methods; Pyrazines; Spectrum Analysis; Valine; Yeast, Dried

1970
Stereochemistry of the conversions of L-threonine and D-threonine into 2-oxobutanoate by the L-threonine and D-threonine dehydratases of Serratia marcescens.
    European journal of biochemistry, 1980, Volume: 106, Issue:1

    Topics: Aminobutyrates; Butyrates; Deuterium; Isoleucine; Isotope Labeling; Serratia marcescens; Stereoisomerism; Threonine; Threonine Dehydratase

1980
Mass spectrometric differentiation of leucine and isoleucine in proteins derived from bacteria or cell culture.
    Biochemical and biophysical research communications, 1981, Sep-16, Volume: 102, Issue:1

    Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cells, Cultured; Deuterium; Gas Chromatography-Mass Spectrometry; Isoleucine; Leucine; Mass Spectrometry; Proteins

1981
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
    Biochemistry, 1999, Mar-30, Volume: 38, Issue:13

    Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly

1999
Site-specific deuterium order parameters and membrane-bound behavior of a peptide fragment from the intracellular domain of HIV-1 gp41.
    Biochemistry, 1999, May-11, Volume: 38, Issue:19

    Topics: Cell Membrane; Deuterium; Gene Products, env; HIV Envelope Protein gp41; Isoleucine; Lipids; Magnetic Resonance Spectroscopy; Peptide Fragments; Protein Conformation

1999
A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins.
    Journal of biomolecular NMR, 1999, Volume: 13, Issue:4

    Topics: Carbon Isotopes; Deuterium; Indicators and Reagents; Isoleucine; Isotope Labeling; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Valine

1999
Evidence for a short-chain carnitine-acylcarnitine translocase in mitochondria specifically related to the metabolism of branched-chain amino acids.
    Molecular genetics and metabolism, 2000, Volume: 69, Issue:1

    Topics: Amino Acids, Branched-Chain; Biological Transport; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Child; Deuterium; Fibroblasts; Humans; Intracellular Membranes; Isoleucine; Mass Spectrometry; Metabolism, Inborn Errors; Mitochondria; Oxidation-Reduction

2000
Probes of a role for remote binding interactions on hydrogen tunneling in the horse liver alcohol dehydrogenase reaction.
    Biochemistry, 2000, Feb-15, Volume: 39, Issue:6

    Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding Sites; Deuterium; Horses; Hydrogen; Isoleucine; Kinetics; Liver; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tritium; Tryptophan

2000
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
    Biochemistry, 2001, Jul-10, Volume: 40, Issue:27

    Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Chromatography, High Pressure Liquid; Deuterium; Diphosphates; Enzyme Inhibitors; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Leucine; Macromolecular Substances; Magnesium; Magnesium Compounds; Mass Spectrometry; Molecular Sequence Data; Pepsin A; Peptide Fragments; Phenylalanine; Protons; Pyrimidinones; Pyrroles

2001
Crystals of trp repressor suitable for high-resolution neutron Laue diffraction studies.
    Acta crystallographica. Section D, Biological crystallography, 2003, Volume: 59, Issue:Pt 1

    Topics: Bacterial Proteins; Crystallization; Deuterium; Diffusion; DNA-Binding Proteins; Escherichia coli; Isoleucine; Neutron Diffraction; Repressor Proteins; Solvents; Valine

2003
Side chain assignments of Ile delta 1 methyl groups in high molecular weight proteins: an application to a 46 ns tumbling molecule.
    Journal of the American Chemical Society, 2003, May-14, Volume: 125, Issue:19

    Topics: Carbon Isotopes; Carrier Proteins; Computer Simulation; Cyclodextrins; Deuterium; Isoleucine; Maltose-Binding Proteins; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular

2003
Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase.
    Biochemistry, 2004, Jan-20, Volume: 43, Issue:2

    Topics: Binding Sites; Deuterium; Escherichia coli Proteins; Folic Acid; Isoleucine; NADP; Nanotechnology; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Tertiary; Spectrophotometry; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Thermodynamics; Threonine; Valine

2004
Evidence for slow motion in proteins by multiple refocusing of heteronuclear nitrogen/proton multiple quantum coherences in NMR.
    Journal of the American Chemical Society, 2004, Feb-11, Volume: 126, Issue:5

    Topics: Anisotropy; Deuterium; Isoleucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Protons; Quantum Theory; Thermodynamics; Ubiquitin

2004
Determinants of substrate specificity in omega-aminotransferases.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Amino Acids; Aminobutyrates; Binding Sites; Biochemistry; Crystallography, X-Ray; Deuterium; DNA; Glutamic Acid; Humans; Isoleucine; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate; Recombinant Fusion Proteins; Spectrophotometry; Substrate Specificity; Time Factors; Transaminases; Tyrosine

2005
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.
    Biochemistry, 2005, Dec-13, Volume: 44, Issue:49

    Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine

2005
A simple and reliable approach to docking protein-protein complexes from very sparse NOE-derived intermolecular distance restraints.
    Journal of biomolecular NMR, 2006, Volume: 36, Issue:1

    Topics: Bacterial Proteins; Buffers; Carbon Isotopes; Crystallography, X-Ray; Deuterium; Hydrogen-Ion Concentration; Isoleucine; Models, Molecular; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Phosphates; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphotransferases (Nitrogenous Group Acceptor); Protein Binding; Protein Structure, Tertiary; Protons; Solvents

2006
An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein.
    Journal of biomolecular NMR, 2009, Volume: 43, Issue:2

    Topics: Alanine; Carbon Isotopes; Culture Media; Deuterium; Escherichia coli; Hemiterpenes; Humans; Isoleucine; Isotope Labeling; Keto Acids; Malate Synthase; Metabolic Networks and Pathways; Nuclear Magnetic Resonance, Biomolecular; Proteins; Succinic Acid; Ubiquitin

2009
Optimal methyl labeling for studies of supra-molecular systems.
    Journal of biomolecular NMR, 2010, Volume: 47, Issue:3

    Topics: Carbon Isotopes; Deuterium; Isoleucine; Leucine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine

2010
High-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination.
    Journal of biomolecular NMR, 2010, Volume: 48, Issue:3

    Topics: Amino Acid Sequence; Carbon Isotopes; Deuterium; Escherichia coli; Fourier Analysis; Humans; Isoleucine; Leucine; Methylation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Quaternary; Proteins; Valine

2010
A simple strategy for ¹³C, ¹H labeling at the Ile-γ2 methyl position in highly deuterated proteins.
    Journal of biomolecular NMR, 2010, Volume: 48, Issue:3

    Topics: Carbon Isotopes; Deuterium; Isoleucine; Isotope Labeling; Leucine; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine; Vitamin B 12

2010
Brief early-life non-specific incorporation of deuterium extends mean life span in Drosophila melanogaster without affecting fecundity.
    Rejuvenation research, 2013, Volume: 16, Issue:2

    Topics: Analysis of Variance; Animals; Deuterium; Drosophila melanogaster; Female; Fertility; Isoleucine; Leucine; Longevity; Male; Mass Spectrometry; Proportional Hazards Models; Survival Analysis; Time Factors

2013
2D IR cross peaks reveal hydrogen-deuterium exchange with single residue specificity.
    The journal of physical chemistry. B, 2013, Dec-12, Volume: 117, Issue:49

    Topics: Antimicrobial Cationic Peptides; Carbon Isotopes; Deuterium; Deuterium Exchange Measurement; Hydrogen; Isoleucine; Lipid Bilayers; Oxygen Isotopes; Proteins; Spectrophotometry, Infrared

2013
Perdeuteration and methyl-selective (1)H, (13)C-labeling by using a Kluyveromyces lactis expression system.
    Journal of biomolecular NMR, 2013, Volume: 57, Issue:3

    Topics: Carbon Isotopes; Deuterium; Gene Expression; Isoleucine; Isotope Labeling; Kluyveromyces; Leucine; Maltose-Binding Proteins; Nuclear Magnetic Resonance, Biomolecular; Proteins; Transaminases; Valine

2013
Detection of intermolecular transferred NOEs in large protein complexes using asymmetric deuteration: HIV-1 gp120 in complex with a CCR5 peptide.
    The FEBS journal, 2016, Volume: 283, Issue:22

    Topics: Binding Sites; Crystallography, X-Ray; Deuterium; HIV Envelope Protein gp120; Humans; Isoleucine; Leucine; Multiprotein Complexes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Binding; Protons; Receptors, CCR5; Tyrosine; Valine

2016