isoleucine has been researched along with asparagine in 153 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (36.60) | 18.7374 |
| 1990's | 30 (19.61) | 18.2507 |
| 2000's | 47 (30.72) | 29.6817 |
| 2010's | 12 (7.84) | 24.3611 |
| 2020's | 8 (5.23) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Smith, GG; Williams, KM | 1 |
| Allin, EP; Guetard, D | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Berghuis, AM; Brayer, GD; Langen, R; McLendon, G; Sherman, F; Warshel, A | 1 |
| Cohen, AS; Harding, J; Jones, LA; Milunsky, A; Skare, I; Skare, J; Skinner, M | 1 |
| Gao, Y; McLendon, G; Pielak, GJ; Williams, RJ | 1 |
| Campbell, RD; Partanen, J | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Chiou, SH; Chung, BC; Hu, MC | 1 |
| Bantia, S; Bell, WR; Dang, CV | 1 |
| Chen, SS; Huisman, TH; Webber, BB; Wilson, JB | 1 |
| Imai, Y; Nakamura, M | 1 |
| Das, G; Hickey, DR; McLendon, D; McLendon, G; Sherman, F | 1 |
| Cantatore, P; Gadaleta, MN; Rainaldi, G; Roberti, M; Saccone, C | 1 |
| Borg, JY; Brennan, SO; Caen, J; Carrell, RW; George, PM; Soria, C; Soria, J | 1 |
| Türker, RK | 1 |
| Dikow, A; Lolova, I | 1 |
| Park, WK; Regoli, D; Rioux, F | 1 |
| Callahan, PX; Ellis, S; McDonald, JK; Zeitman, BB | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Hellebust, JA; Liu, MS | 1 |
| Melera, PW; Momeni, C; Rusch, HP | 1 |
| Mehler, AH; Midelfort, CF | 1 |
| Peterkofsky, A; Powers, DM | 1 |
| Halpern, YS | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Hanson, LE; Meade, RJ; Oestemer, GA | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Beintema, JJ; Scheffer, AJ; Zwiers, H | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Berger, H; Yanofsky, C | 1 |
| Kaneda, T | 1 |
| Elliott, WH; May, BK | 1 |
| Buu-Hoï, NP; Hauspie, R; Lambelin, G; Nicolle, J | 1 |
| Coan, MH; Roberts, RC; Travis, J | 1 |
| Benuck, M; Lajtha, A; Stern, F | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Graeber, W | 1 |
| Bjarnason, J; Carpenter, KJ | 1 |
| Nozu, Y; Okada, Y; Ono, T | 1 |
| Ruth, RC; Soja, DM; Wold, F | 1 |
| Waidyasekera, PL | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Bodnaryk, RP; Levenbook, L | 1 |
| Chaudhury, RR; Datta, H | 1 |
| Jefferson, LS; Korner, A | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Hubbard, JS; Stadtman, ER | 1 |
| Kiyama, S; Makita, M; Watanabe, Y; Yamamoto, S | 1 |
| Foley, BT; Moehring, JM; Moehring, TJ | 1 |
| Offer, G; Sessions, R | 1 |
| Drapier, D; Gaudriault, S; Girard-Bascou, J; Ketchner, SL; Olive, J; Wollman, FA | 1 |
| Koshy, TI; Luntz, TL; Margoliash, E; Sanishvili, R; Schejter, A; Vig, I | 1 |
| Koshy, TI; Luntz, TL; Margoliash, E; Plotkin, B; Schejter, A | 1 |
| Pishko, EJ; Robertus, JD | 1 |
| Dötsch, V; Oswald, RE; Wagner, G | 1 |
| Castiglione Morelli, MA; Gibson, TJ; Joseph, C; Musco, G; Nilges, M; Pastore, A; Stier, G | 1 |
| Alcazar-Roman, L; Doyle, DF; Parikh, S; Pielak, GJ; Waldner, JC | 1 |
| Galjaard, H; Hoogeveen, AT; Meijer, N; Oostra, BA; Tamanini, F; Verheij, C; Willems, PJ | 1 |
| Clausen, JO; Fridberg, M; Hansen, T; Møller, AM; Pedersen, O; Rasmussen, SK; Urhammer, SA | 1 |
| Aston, CE; Ehrlich, GD; Furey, W; Gabbaizedeh, D; Gates, LK; Gorry, MC; Preston, RA; Ulrich, C; Whitcomb, DC; Zhang, Y | 1 |
| Abildgaard, S; Jensen, G; Nordestgaard, BG; Steffensen, R; Tybjaerg-Hansen, A; Wittrup, HH | 1 |
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Brandt, U; Meunier, B; Ortwein, C; Rich, PR | 1 |
| Akeo, K; Kudoh, J; Mashima, Y; Oguchi, Y; Saga, M; Shimizu, N | 1 |
| Curtis, J; Duraisingh, MT; Warhurst, DC | 1 |
| Ash, DE; Dismukes, GC; Khangulov, SV; Sossong, TM | 1 |
| Clausen, JO; Eiberg, H; Ekstrøm, CT; Hansen, T; Møller, AM; Nyholm, B; Pedersen, O; Schmitz, O; Urhammer, SA | 1 |
| Munagala, NR; Wang, CC | 1 |
| Anar, B; Bakker, CE; Bontekoe, C; Galjaard, H; Hoogeveen, AT; Oostra, BA; Tamanini, F; van Unen, L; Willemsen, R; Yoshida, M | 1 |
| Abbenante, G; Alewood, D; Alewood, PF; Begun, J; Bergman, DA; Brinkworth, RI; Fairlie, DP; March, DR; Martin, JL; Reid, RC; Schindeler, A; Wickramasinghe, WA | 1 |
| Sahin-Tóth, M | 1 |
| Gonda, TJ; McCormack, MP | 1 |
| Sahin-Tóth, M; Tóth, M | 2 |
| Fischer, U; Keidel, EM; Laggerbauer, B; Ostareck, D; Ostareck-Lederer, A | 1 |
| Harding, MM; Haymet, AD; Ward, LG | 1 |
| Roninson, IB; Rose, E; Ruth, A; Stein, WD | 1 |
| Gráf, L; Juhász, G; Kaslik, G; Katona, G; Kénesi, E; Szilágyi, L | 1 |
| Chanas, B; Coulter, SJ; Ghanayem, B; Goldstein, JA; Johnson, EF; Tsao, CC; Wester, MR | 1 |
| Gergis, MR; Grogan, WM; Kodsi, EM; Langston, TB; Wallace, TJ | 1 |
| Barile, M; Wang, GK; Wang, SY | 1 |
| Atreya, CD; Hofmann, J; Nakhasi, HL; Ramanujam, M | 1 |
| Liang, J; Luba, J; McGee, MP | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Cui, J; Heard, TS; Huang, L; Li, Y; Lo, JL; Schaeffer, JM; Wright, SD; Yu, J | 1 |
| Schwalbe, RA; Wingo, CS; Xia, SL | 1 |
| Acharya, A; Gal, J; Moll, JR; Ruvinov, SB; Vinson, C | 1 |
| Bohác, M; Damborský, J; Koca, J; Monincová, M; Nagata, Y; Prokop, M; Prokop, Z; Tsuda, M | 1 |
| Eriksson, S; Saada, A; Wang, L | 1 |
| Ihara, Y; Mitsumori, R; Morishima-Kawashima, M; Qi, Y; Sato, T | 1 |
| Barden, JA; Dao-Ung, LP; Fuller, SJ; Gu, BJ; Li, C; Petrou, S; Shemon, AN; Sluyter, R; Smart, ML; Wiley, JS | 1 |
| Cusimano, A; D'Adamo, MC; De Curtis, A; Imbrici, P; Pessia, M | 1 |
| FRIEDMAN, ME; ROESSLER, WG | 1 |
| WOLLENWEBER, P | 1 |
| MCCOY, TA; ORR, G; PATTERSON, MK | 1 |
| LORINCZ, AB; RYAN, WL | 1 |
| Breuer, LH; Loosli, JK; Pond, WG; Warner, RG | 1 |
| DELALLOSA, P; JUTISZ, M; TERTRIN, C | 1 |
| SASAKI, T; SHIMURA, K; SUGAWARA, K | 1 |
| HACHISUKA, Y | 1 |
| GERIFFIN, G; KESNER, L; MUNTWYLER, E | 1 |
| SAAMELI, K | 1 |
| BERNFIELD, MR; BRIMACOMBE, RL; LEDER, P; NIRENBERG, MW; ROTTMAN, FM; TRUPIN, JS | 1 |
| Lam, E; Parkin, NT | 1 |
| Blum, LE; Clemente, JC; Dunn, BM; Goodenow, MM; Hemrajani, R | 1 |
| Bambara, RA; Chen, R; Kim, B; Lee, K; Mansky, LM; Reynolds, HM; Skasko, M; Weiss, KK | 1 |
| Craik, CS; Fletterick, RJ; Ruggles, SW | 1 |
| Segaloff, DL; Tao, YX | 1 |
| Chang, YJ; Lin, SW; Walsh, PN; Yang, X | 1 |
| Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA | 1 |
| Cho, H; Hamza, A; Tai, HH; Zhan, CG | 1 |
| Acton, RT; Barton, JC; Bohannon, SB; Niyongere, S; Rivers, CA | 1 |
| Amano, T; Fujita, T; Hayashi, T; Nakayama, M; Tanaka, S; Tani, Y; Yoshimura, K | 1 |
| Gupta, A; Lewis, F; Mao, Q; Unadkat, JD; Vethanayagam, RR; Wang, H; Zhang, Y | 1 |
| Guo, JF; Hayflick, SJ; Long, ZG; Tang, BS; Westaway, SK; Xia, K; Zhang, YH; Zhao, AL | 1 |
| Dalal, S; Starcevic, D; Sweasy, J | 1 |
| Roy, S; Sen, S | 1 |
| Guo, D; Jamburuthugoda, VK; Kim, B; Wedekind, JE | 1 |
| Chung, S; Civelli, O; Okamura, N; Pai, R; Reinscheid, RK; Wang, Z; Xu, YL; Zeng, J | 1 |
| Eblan, MJ; Giasson, BI; Goker-Alpan, O; Hurtig, HI; Lee, VM; Nguyen, J; Sidransky, E; Trojanowski, JQ | 1 |
| Dalbey, RE; Ekici, OD; Karla, A; Lively, MO; Paetzel, M; Pei, D | 1 |
| Frillingos, S; Georgopoulou, E; Karatza, P; Panos, P | 1 |
| Fenton, C; Hjerde, E; Thorvaldsen, S; Willassen, NP | 1 |
| Bassell, GJ; Dictenberg, JB; Feng, Y; Ku, L; Li, W; Wang, H | 1 |
| Bosak, A; Gazić, I; Kovarik, Z; Vinković, V | 1 |
| Frillingos, S; Georgopoulou, E; Papakostas, K | 1 |
| Chen, W; Dong, X; Qi, F; Shi, W; Tong, H | 1 |
| Baloh, RH; Fahrner, T; Le, N; Milbrandt, J; Nagarajan, R; Ryu, E; Strickland, A; Yang, M | 1 |
| Bird, TD; Jayadev, S; Klunk, W; Leverenz, JB; Stahl, J; Steinbart, E; Yu, CE | 1 |
| Luo, H; Robb, FT; Zhang, P | 1 |
| Franke, PE; Frommann, I; Gaebel, W; Häfner, H; Höfels, S; Klosterkötter, J; Landsberg, MW; Lennertz, L; Maier, W; Mössner, R; Petrovsky, N; Pukrop, R; Quednow, BB; Schuhmacher, A; Schulze-Rauschenbach, S; Steinbrecher, A; Wagner, M; Wölwer, W | 1 |
| Celestino, R; Faustino, A; Gouveia, A; Lima, J; Lopes, JM; Máximo, V; Soares, P; Vinagre, J | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| Buragohain, AK; Dutta, M; Ray, SK; Satapathy, SS | 1 |
| Angsuthanasombat, C; Juntadech, T; Kanchanawarin, C; Kanintronkul, Y; Katzenmeier, G | 1 |
| do Carmo Carreiras, M; Galdeano, C; Juárez-Jiménez, J; Luque, FJ; Marco-Contelles, J; Martins, C; Mendes, E; Ramsay, RR; Silva, DB | 1 |
| Flesch, BK; Just, B; Schottstedt, V; Spallek, H | 1 |
| Fukutake, N; Hiraoka, N; Imaizumi, A; Ito, T; Katayama, K; Kikuchi, S; Ono, N; Saruki, N; Shimada, K; Shiraishi, K; Ueno, M; Yamakado, M; Yamamoto, H | 1 |
| Boerwinkle, E; Chang, P; Coresh, J; Köttgen, A; Rebholz, CM; Selvin, E; Tin, A; Wagenknecht, LE; Yu, B; Zheng, Z | 1 |
| Fatima, S; Hafeez, A; Ijaz, AIA; Memon, AA; Waseem, M | 1 |
| Cruz, M; Locia-Morales, D; Meyre, D; Sharma, T; Valladares-Salgado, A; Vázquez-Moreno, M; Wacher-Rodarte, N | 1 |
| Cleary, S; Cowan, JA; Harvey, SR; Sen, S; Thompson, Z; Wachnowsky, C | 1 |
| Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X | 1 |
| Bai, M; Chen, J; Dai, H; Han, F; Lin, W; Wang, J; Weng, C; Xie, X; Zhu, H | 1 |
| Birkou, M; Delegkou, GN; Episkopou, V; Fragkaki, N; Marousis, KD; Spyroulias, GA; Toro, T | 1 |
| Fischer, M; Görlich, D; Huyton, T; Jaiswal, M; Taxer, W | 1 |
| Bae, E; Jo, HA; Kim, DJ; Kim, DK; Kim, YS; Lee, S; Seo, JH; Yang, SH; Yu, MY | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
2 review(s) available for isoleucine and asparagine
| Article | Year |
|---|---|
A critical evaluation of the application of amino acid racemization to geochronology and geothermometry.
Topics: Amino Acids; Asparagine; Bacteria; Bone and Bones; Chemical Phenomena; Chemistry; Chronology as Topic; Collagen; Fossils; Geological Phenomena; Geology; Glutamine; Hydrolysis; Isoleucine; Kinetics; Minerals; Paleontology; Seawater; Temperature; Tooth; Water | 1977 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
1 trial(s) available for isoleucine and asparagine
| Article | Year |
|---|---|
In vivo selection for a specific genotype of dihydropteroate synthetase of Plasmodium falciparum by pyrimethamine-sulfadoxine but not chlorproguanil-dapsone treatment.
Topics: Amino Acid Sequence; Animals; Antimalarials; Arginine; Asparagine; Child; Dapsone; Dihydropteroate Synthase; Drug Therapy, Combination; Genes, Protozoan; Genetic Variation; Genotype; Humans; Isoleucine; Malaria, Falciparum; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Proguanil; Pyrimethamine; Sulfadoxine | 1998 |
150 other study(ies) available for isoleucine and asparagine
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The effect on macromolecular synthesis of amino acid deprivation of hamster kidney cells.
Topics: Amino Acids; Arginine; Asparaginase; Asparagine; Cells, Cultured; DNA; Isoleucine; Kinetics; Leucine; Protein Biosynthesis; RNA; Tryptophan | 1977 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
Effect of the Asn52----Ile mutation on the redox potential of yeast cytochrome c. Theory and experiment.
Topics: Amino Acid Sequence; Asparagine; Cytochrome c Group; Electrochemistry; Electron Transport; Isoleucine; Mutagenesis; Oxidation-Reduction; Protein Conformation; Saccharomyces cerevisiae; Structure-Activity Relationship; Water | 1992 |
A new transthyretin mutation associated with amyloidotic vitreous opacities. Asparagine for isoleucine at position 84.
Topics: Aged; Amyloidosis; Asparagine; Base Sequence; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Eye Diseases; Female; Humans; Isoleucine; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prealbumin; Vitreous Body | 1992 |
Electron-proton coupling in cytochrome c studied using protein variants.
Topics: Amino Acid Sequence; Asparagine; Cytochrome c Group; Hydrogen Bonding; Ion Channels; Isoleucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Mutation; Oxidation-Reduction; Protein Conformation; Protons; Saccharomyces cerevisiae | 1992 |
Substitution of Ile-172 to Asn in the steroid 21-hydroxylase B (P450c21B) gene in a Finnish patient with the simple virilizing form of congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Asparagine; Base Sequence; Child; Cloning, Molecular; DNA; Finland; Humans; Isoleucine; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Steroid 21-Hydroxylase | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
A missense mutation at Ile172----Asn or Arg356----Trp causes steroid 21-hydroxylase deficiency.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Arginine; Asparagine; Base Sequence; Codon; DNA; Female; Genes; Humans; Isoleucine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Plasmids; Reference Values; Restriction Mapping; Steroid 21-Hydroxylase; Steroid Hydroxylases; Transfection; Tryptophan | 1990 |
Polymerization defect of fibrinogen Baltimore III due to a gamma Asn308----Ile mutation.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Chromatography, High Pressure Liquid; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinogens, Abnormal; Humans; Isoleucine; Molecular Sequence Data; Mutation; Polymers; Serine Endopeptidases | 1990 |
Hb F-Forest Park, a new A gamma variant with two amino acid substitutions, 75(E19)Ile----Thr and 73(E17)Asp----Asn, which can be identified in adults by gene-mapping analysis.
Topics: Asparagine; Aspartic Acid; Base Sequence; DNA; DNA Restriction Enzymes; Female; Fetal Blood; Fetal Hemoglobin; Genes; Genetic Variation; Hemoglobins, Abnormal; Humans; Infant, Newborn; Isoleucine; Male; Pedigree; Pregnancy; Threonine | 1985 |
Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase).
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Decanoic Acids; DNA; Isoleucine; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Progesterone; Rabbits; Saccharomyces cerevisiae; Serine; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Testosterone; Threonine; Transformation, Genetic; Valine | 1989 |
Dramatic thermostabilization of yeast iso-1-cytochrome c by an asparagine----isoleucine replacement at position 57.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Cytochrome c Group; Cytochromes c; DNA, Fungal; Hot Temperature; Isoleucine; Molecular Sequence Data; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1989 |
The complete nucleotide sequence, gene organization, and genetic code of the mitochondrial genome of Paracentrotus lividus.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Biological Evolution; Chromosome Mapping; Codon; DNA, Mitochondrial; Electron Transport Complex IV; Genetic Code; Isoleucine; Lysine; Methionine; Molecular Sequence Data; Proteins; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Sea Urchins | 1989 |
New carbohydrate site in mutant antithrombin (7 Ile----Asn) with decreased heparin affinity.
Topics: Antithrombin III; Asparagine; Female; Genetic Variation; Heparin; Humans; Isoleucine; Kinetics; Middle Aged; Mutation; Peptide Mapping; Peptides; Protein Binding | 1988 |
Change of activity of angiotensins I and II in the isolated perfused guinea-pig lung.
Topics: Angiotensin II; Animals; Aorta; Asparagine; Biological Assay; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; Isoleucine; Lung; Male; Perfusion; Pressure; Rabbits; Rats; Sarcosine | 1973 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
II. Pharmacology of angiotensin antagonists.
Topics: Angiotensin II; Animals; Asparagine; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Isoleucine; Leucine; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Rats; Sarcosine; Serotonin; Stomach | 1973 |
Angiotensinase activity of dipeptidyl aminopeptidase I (cathepsin C) of rat liver.
Topics: Angiotensin II; Animals; Arginine; Asparagine; Carboxypeptidases; Cathepsins; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dipeptides; Endopeptidases; Humans; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Liver; Lysosomes; Proline; Rats; Species Specificity; Structure-Activity Relationship | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Utilization of amino acids as nitrogen sources, and their effects on nitrate reductase in the marine diatom Cyclotella cryptica.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Asparagine; Cell-Free System; Chlorophyll; Eukaryota; Glutamates; Glutamine; Glycine; Isoleucine; Nitrate Reductases; Nitrates; Ornithine; Plant Proteins; Proline; Seawater; Urea; Water Microbiology | 1974 |
Analysis of isoaccepting tRNAs during the growth phase mitotic cycle of Physarum polycephalum.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Asparagine; Cell Division; Chromatography, Ion Exchange; Codon; Genetic Code; Glycine; Histidine; Isoleucine; Leucine; Mitosis; Myxomycetes; Protein Biosynthesis; RNA, Transfer; Tritium; Tryptophan; Valine | 1974 |
Deamidation in vivo of an asparagine residue of rabbit muscle aldolase.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Fructose-Bisphosphate Aldolase; Half-Life; Isoelectric Focusing; Isoleucine; Isotope Labeling; Macromolecular Substances; Mathematics; Muscles; Peptides; Rabbits | 1972 |
The presence of N-(purin-6-ylcarbamoyl)threonine in transfer ribonucleic acid species whose codons begin with adenine.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Arginine; Asparagine; Benzoates; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Genetic Code; Glycolates; Isoleucine; Leucine; Lysine; Methionine; Purine Nucleotides; RNA, Bacterial; RNA, Transfer; Serine; Succinimides; Threonine; Tritium | 1972 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
Reevaluation of the isoleucine requirement of the young pig.
Topics: Amino Acids; Ammonia; Animals; Asparagine; Blood Urea Nitrogen; Body Weight; Diet; Isoleucine; Male; Nutritional Requirements; Swine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Amino-acid sequences of red-deer and roe-deer pancreatic ribonucleases.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Deer; Glycosides; Isoleucine; Lysine; Methionine; Methods; Pancreas; Ribonucleases; Species Specificity | 1973 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Biosynthesis of branched-chain fatty acids. IV. Factors affecting relative abundance of fatty acids produced by Bacillus subtilis.
Topics: Asparagine; Bacillus subtilis; Biotin; Chromatography, Gas; Culture Media; Fatty Acids; Isoleucine; Leucine; Valine | 1966 |
Characteristics of extracellular protease formation by Bacillus subtilis and its control by amino acid repression.
Topics: Amino Acids; Amylases; Asparagine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Dactinomycin; Depression, Chemical; Enzyme Repression; Glutamates; Isoleucine; Peptide Hydrolases; Proline; Time Factors | 1968 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Human pancreatic enzymes. Isolation and properties of a major form of chymotrypsin.
Topics: Acetone; Amino Acids; Animals; Asparagine; Butanones; Calcium Chloride; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis, Disc; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Quaternary Ammonium Compounds; Rabbits; Serine; Species Specificity; Spectrophotometry; Sulfates; Trypsin; Ultracentrifugation; Ultraviolet Rays | 1971 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Mechanisms of heat damage in proteins. 2. Chemical changes in pure proteins.
Topics: Albumins; Ammonia; Asparagine; Chemical Phenomena; Chemistry; Cystine; Glutamine; Hot Temperature; Isoleucine; Lysine; Protein Denaturation; Serum Albumin, Bovine; Sulfides | 1970 |
Amino acid sequences of some common Japanese strains of tobacco mosaic virus.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Endopeptidases; Isoleucine; Threonine; Tobacco Mosaic Virus; Valine | 1970 |
Purification and characterization of enolases from coho (Oncorhynchus kisutch) and chum (Oncorhynchus keta) salmon.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Carboxypeptidases; Cysteine; Cystine; Electrophoresis; Enzyme Activation; Fluorides; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Magnesium; Molecular Weight; Phosphopyruvate Hydratase; Salmonidae; Tryptophan | 1970 |
Abnormal encystment after the action of certain amino-acids.
Topics: Amino Acids; Amoeba; Animals; Asparagine; Cystine; Isoleucine; Lysine; Tryptophan | 1971 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
The antidiuretic hormone blocking effect of some oxytocin analogues.
Topics: Amino Acid Sequence; Animals; Asparagine; Diuresis; Isoleucine; Kidney; Male; Oxytocin; Rats; Serine; Vasopressins; Water | 1968 |
Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver.
Topics: Amino Acids; Animals; Arginine; Asparagine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Perfusion; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Tryptophan; Valine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Regulation of glutamine synthetase. VI. Interactions of inhibitors for Bacillus licheniformis glutamine synthetase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Ammonium Chloride; Asparagine; Aspartic Acid; Bacillus; Carbamates; Drug Antagonism; Drug Synergism; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydroxamic Acids; Isoleucine; Kinetics; Ligases | 1967 |
Practical gas-liquid chromatographic method for the determination of amino acids in human serum.
Topics: Amino Acids; Arginine; Asparagine; Chromatography, Gas; Formates; Formic Acid Esters; Glutamine; Humans; Isoleucine; Leucine; Tyrosine | 1982 |
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Animals; Asparagine; Bacterial Toxins; Base Sequence; CHO Cells; Cricetinae; Diphtheria Toxin; Drug Resistance; Exotoxins; Glycine; Histidine; Humans; Isoleucine; Molecular Sequence Data; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Plasmids; Point Mutation; Polymorphism, Restriction Fragment Length; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid; Serine; Transfection; Virulence Factors | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Chloroplasts can accommodate inclusion bodies. Evidence from a mutant of Chlamydomonas reinhardtii defective in the assembly of the chloroplast ATP synthase.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Centrifugation, Density Gradient; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Crosses, Genetic; Genes, Fungal; Immunohistochemistry; Inclusion Bodies; Isoleucine; Macromolecular Substances; Molecular Sequence Data; Phenotype; Point Mutation; Proton-Translocating ATPases; Restriction Mapping; Tyrosine | 1995 |
Effects of mutating Asn-52 to isoleucine on the haem-linked properties of cytochrome c.
Topics: Animals; Asparagine; Cyanides; Cytochrome c Group; Heme; Hydrogen-Ion Concentration; Ions; Isoleucine; Mutagenesis, Site-Directed; Oxidation-Reduction; Rats; Saccharomyces cerevisiae | 1994 |
The significance of denaturant titrations of protein stability: a comparison of rat and baker's yeast cytochrome c and their site-directed asparagine-52-to-isoleucine mutants.
Topics: Amino Acid Sequence; Animals; Asparagine; Calorimetry; Cytochrome c Group; Drug Stability; Isoleucine; Kinetics; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Rats; Saccharomyces cerevisiae; Urea | 1994 |
Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Allosteric Regulation; Asparagine; Binding Sites; Histidine; Histidine Decarboxylase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Phenylalanine; Pyruvates; Pyruvic Acid; Recombinant Proteins; Tyrosine; Valine | 1993 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Topics: Asparagine; Binding Sites; Carrier Proteins; Fragile X Syndrome; Humans; Isoleucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Phenotype; Protein Conformation; Protein Structure, Tertiary; Proteins; RNA-Binding Proteins; Sequence Homology, Amino Acid | 1996 |
Changing the transition state for protein (Un) folding.
Topics: Asparagine; Calorimetry; Circular Dichroism; Cytochrome c Group; Cytochromes c; Genetic Variation; Guanidine; Guanidines; Isoleucine; Kinetics; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Protein Folding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Thermodynamics | 1996 |
FMRP is associated to the ribosomes via RNA.
Topics: Asparagine; Fragile X Mental Retardation Protein; Isoleucine; Nerve Tissue Proteins; Point Mutation; Ribosomes; RNA; RNA-Binding Proteins; Structure-Activity Relationship; Ultracentrifugation | 1996 |
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Topics: Administration, Oral; Adult; Aged; Alanine; Amino Acids; Asparagine; C-Peptide; Codon; DNA-Binding Proteins; Female; Glucose; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Serine; Transcription Factors; Valine | 1997 |
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Topics: Acute Disease; Adenine; Asparagine; Chromosome Mapping; Chromosomes, Human, Pair 7; Chronic Disease; Female; Genetic Linkage; Hospitalization; Humans; Isoleucine; Male; Pancreatitis; Pedigree; Point Mutation; Recurrence; Thymine; Trypsinogen | 1997 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Disease; Female; Gene Frequency; Glutamic Acid; Glycine; Heterozygote; Humans; Isoleucine; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Point Mutation; Risk Factors; Serine; Triglycerides | 1997 |
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Effects of mutation of residue I67 on redox-linked protonation processes in yeast cytochrome c oxidase.
Topics: Asparagine; Electron Transport Complex IV; Glutamic Acid; Heme; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Macromolecular Substances; Models, Molecular; Oxidation-Reduction; Point Mutation; Potentiometry; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae | 1998 |
A novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adult; Asparagine; Codon; Cyclic Nucleotide Phosphodiesterases, Type 6; Fundus Oculi; Humans; Isoleucine; Japan; Male; Middle Aged; Pedigree; Phosphoric Diester Hydrolases; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa; Visual Fields | 1998 |
L-arginine binding to liver arginase requires proton transfer to gateway residue His141 and coordination of the guanidinium group to the dimanganese(II,II) center.
Topics: Animals; Arginase; Arginine; Asparagine; Binding Sites; Borates; Citrulline; Electron Spin Resonance Spectroscopy; Guanidine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Liver; Lysine; Manganese; Mutagenesis, Site-Directed; Ornithine; Protons; Rats; Substrate Specificity | 1998 |
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
Topics: Adult; Amino Acid Substitution; Asparagine; C-Peptide; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Genetic Variation; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Islets of Langerhans; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Serine; Transcription Factors; White People | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations.
Topics: Adhesins, Bacterial; Animals; Asparagine; Carrier Proteins; Cell Nucleus; COS Cells; Cytoplasm; Exportin 1 Protein; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Isoleucine; Karyopherins; Mutation; Nerve Tissue Proteins; Receptors, Cytoplasmic and Nuclear; RNA-Binding Proteins; RNA, Messenger; RNA, Ribosomal; Transcription, Genetic | 1999 |
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Topics: Aminobutyrates; Asparagine; Binding Sites; Computer Simulation; Crystallography, X-Ray; HIV Protease Inhibitors; HIV-1; Isoleucine; Leucine; Lysine; Models, Molecular; Molecular Mimicry; Oligopeptides; Peptides, Cyclic; Phenylalanine; Protein Conformation; Stereoisomerism; Valine | 1999 |
Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.
Topics: Animals; Asparagine; Calcium; Catalysis; Enteropeptidase; Enzyme Activation; Humans; Isoleucine; Pancreatitis; Point Mutation; Rats; Recombinant Proteins; Trypsinogen | 1999 |
Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor beta subunit.
Topics: Amino Acid Substitution; Animals; Asparagine; Cell Differentiation; Cell Line; Cell Line, Transformed; Glutamic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Isoleucine; Macromolecular Substances; Mice; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Valine | 2000 |
High-affinity Ca(2+) binding inhibits autoactivation of rat trypsinogen.
Topics: Animals; Asparagine; Calcium; Enzyme Activation; Humans; Isoleucine; Mutation; Pancreas; Protein Binding; Rats; Threonine; Trypsinogen | 2000 |
Evidence that fragile X mental retardation protein is a negative regulator of translation.
Topics: Animals; Asparagine; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Intellectual Disability; Isoleucine; Microinjections; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oocytes; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Repressor Proteins; Ribosomal Proteins; RNA-Binding Proteins; RNA, Messenger; Xenopus laevis; Xenopus Proteins | 2001 |
Hydrophobic analogues of the winter flounder 'antifreeze' protein.
Topics: Alanine; Amino Acid Substitution; Aminobutyrates; Animals; Antifreeze Proteins; Asparagine; Aspartic Acid; Flounder; Freezing; Ice; Isoleucine; Leucine; Protein Engineering; Protein Structure, Secondary; Structure-Activity Relationship; Threonine | 2001 |
Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Asparagine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colchicine; Drug Resistance, Multiple; Etoposide; Genetic Vectors; Glycine; Humans; Isoleucine; Mice; Mutagenesis, Site-Directed; Protein Conformation; Transduction, Genetic; Transfection; Valine; Vinblastine | 2001 |
Comparative in vitro studies on native and recombinant human cationic trypsins. Cathepsin B is a possible pathological activator of trypsinogen in pancreatitis.
Topics: Amino Acid Substitution; Asparagine; Catalysis; Cathepsin B; Cloning, Molecular; Enzyme Activation; Escherichia coli; Humans; Hydrogen-Ion Concentration; Isoleucine; Pancreatitis; Recombinant Proteins; Trypsin; Trypsin Inhibitor, Kazal Pancreatic; Trypsinogen; Tumor Cells, Cultured | 2001 |
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis].
Topics: Arginine; Asparagine; Chronic Disease; Enzyme Induction; Histidine; Humans; Isoleucine; Mutation; Pancreatitis; Trypsinogen | 2001 |
Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Histidine; Humans; Hydroxylation; Isoleucine; Kinetics; Mephenytoin; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Recombinant Fusion Proteins; Serine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Threonine | 2001 |
Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase.
Topics: Acetylcholinesterase; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carboxylesterase; Carboxylic Ester Hydrolases; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA, Complementary; Enzyme Activation; Humans; Isoleucine; Liver; Lung; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Sterol Esterase; Threonine | 2001 |
A phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
Topics: Amino Acid Motifs; Animals; Asparagine; Batrachotoxins; Cells, Cultured; Drug Interactions; Humans; Insecticides; Isoleucine; Lysine; Methionine; Mutagenesis, Site-Directed; Nitriles; Patch-Clamp Techniques; Phenylalanine; Pyrethrins; Rats; Sodium Channels; Transfection | 2001 |
Effect of site-directed asparagine to isoleucine substitutions at the N-linked E1 glycosylation sites on rubella virus viability.
Topics: Amino Acid Substitution; Animals; Asparagine; Chlorocebus aethiops; Culture Media, Conditioned; Glycosylation; Immunoblotting; Isoleucine; Reverse Transcriptase Polymerase Chain Reaction; Rubella virus; Transfection; Vero Cells; Viral Envelope Proteins; Virion | 2001 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.
Topics: Amino Acid Sequence; Animals; Asparagine; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Cell Line; Chenodeoxycholic Acid; DNA-Binding Proteins; Humans; Isoleucine; Ligands; Liver; Mice; Mutagenesis, Site-Directed; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Structure-Activity Relationship; Transcription Factors | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
A heterodimerizing leucine zipper coiled coil system for examining the specificity of a position interactions: amino acids I, V, L, N, A, and K.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Chickens; Circular Dichroism; Dimerization; Isoleucine; Leucine; Leucine Zippers; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Transcription Factors; Ultracentrifugation; Valine | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
Kinetic properties of mutant human thymidine kinase 2 suggest a mechanism for mitochondrial DNA depletion myopathy.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Asparagine; Binding, Competitive; Chromatography, Gel; Cloning, Molecular; DNA Mutational Analysis; DNA, Complementary; DNA, Mitochondrial; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Isoleucine; Kinetics; Mitochondrial Myopathies; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Point Mutation; Sequence Homology, Amino Acid; Thymidine Kinase | 2003 |
Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
Topics: Amino Acid Substitution; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Asparagine; Aspartic Acid; Aspartic Acid Endopeptidases; Carbamates; Cell Line; Cell-Free System; CHO Cells; Cricetinae; Culture Media; Dipeptides; Endopeptidases; Humans; Intracellular Fluid; Isoleucine; Membrane Proteins; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Presenilin-1; Presenilin-2; Serine Proteinase Inhibitors; Threonine; Transfection; Up-Regulation; Valine | 2003 |
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor.
Topics: Asparagine; Cell Line; Humans; Isoleucine; Leukocytes, Mononuclear; Mutation; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Signal Transduction | 2003 |
Functional characterization of an episodic ataxia type-1 mutation occurring in the S1 segment of hKv1.1 channels.
Topics: Amino Acid Substitution; Animals; Asparagine; Biophysical Phenomena; Biophysics; Cerebellar Ataxia; Electric Conductivity; Humans; Ion Channel Gating; Isoleucine; Kinetics; Kv1.1 Potassium Channel; Mutation; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Xenopus laevis | 2003 |
Growth of Listeria monocytogenes in defined media.
Topics: Alanine; Arginine; Asparagine; Culture Media; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Listeria monocytogenes; Methionine; Proteins; Valine | 1961 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
CARBON DIOXIDE FIXATION IN THE JA-1 SARCOMA IN VITRO.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fumarates; Glutamates; Glutamine; In Vitro Techniques; Isoleucine; Leucine; Metabolism; Propionates; Proteins; Pyruvates; Sarcoma; Sarcoma, Experimental; Succinates | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
[STUDIES ON AMINO ACIDS REQUIRED FOR COLONY FORMATION OF SUBLETHALLY HEATED SPORES OF BACILLUS SUBTILIS].
Topics: Alanine; Amino Acids; Asparagine; Bacillus subtilis; Culture Media; Glutamates; Hot Temperature; Isoleucine; Lysine; Spores, Bacterial | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
QUANTITATIVE COMPARISON BETWEEN OXYTOCIN AND FOUR RELATED NEUROHYPOPSIAL PEPTIDES ON THE HUMAN UTERUS IN SITU.
Topics: Asparagine; Biological Assay; Female; Humans; Isoleucine; Oxytocics; Oxytocin; Peptides; Pharmacology; Pituitary Hormones, Posterior; Postpartum Period; Serine; Uterus | 1964 |
RNA CODEWORDS AND PROTEIN SYNTHESIS, VI. ON THE NUCLEOTIDE SEQUENCES OF DEGENERATE CODEWORD SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE.
Topics: Asparagine; Base Sequence; Carbon Isotopes; Escherichia coli; Genetic Code; Isoleucine; Lysine; Nucleotides; Protein Biosynthesis; Proteins; Research; Ribosomes; RNA; Tyrosine | 1965 |
Amprenavir resistance imparted by the I50V mutation in HIV-1 protease can be suppressed by the N88S mutation.
Topics: Asparagine; Carbamates; Drug Resistance, Viral; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Isoleucine; Microbial Sensitivity Tests; Mutation; Serine; Sulfonamides; Valine | 2003 |
Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N.
Topics: Alanine; Anti-HIV Agents; Asparagine; Aspartic Acid; Binding Sites; Drug Resistance, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoleucine; Kinetics; Methionine; Mutagenesis, Site-Directed; Nelfinavir; Ritonavir; Valine | 2003 |
A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
Topics: Amino Acid Substitution; Asparagine; Bacteriophage M13; Base Pair Mismatch; Binding Sites; Deoxyribonucleotides; DNA Primers; Gene Frequency; Glutamine; HIV Reverse Transcriptase; HIV-1; Isoleucine; Kinetics; Lac Operon; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Substrate Specificity; Templates, Genetic; Valine | 2004 |
Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Asparagine; Catalysis; Granzymes; Isoleucine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Library; Protein Conformation; Protein Structure, Tertiary; Rats; Serine Endopeptidases; Substrate Specificity; Thermodynamics; Tyrosine | 2004 |
Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation.
Topics: Asparagine; Cell Line; Codon; Gene Expression Regulation; Genetic Variation; Humans; Isoleucine; Lysine; Mutation; Receptor, Melanocortin, Type 3; Receptors, G-Protein-Coupled; Receptors, LH; Threonine; Valine | 2004 |
Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.
Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blood Coagulation; Blood Platelets; Cell Line; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor IXa; Factor VIIIa; Factor X; Humans; Isoleucine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Platelet Activation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors; Valine | 2004 |
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone | 2004 |
Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Chromatography, Affinity; Coenzymes; Escherichia coli; Glutathione Transferase; Humans; Hydroxyprostaglandin Dehydrogenases; Isoleucine; Kinetics; Models, Molecular; Models, Structural; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NAD; Protein Binding; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Valine | 2005 |
Allele frequencies of hemojuvelin gene (HJV) I222N and G320V missense mutations in white and African American subjects from the general Alabama population.
Topics: Adolescent; Adult; Alabama; Alleles; Amino Acid Substitution; Asparagine; Black or African American; Female; Gene Frequency; Genetics, Population; Glycine; GPI-Linked Proteins; Hemochromatosis Protein; Humans; Isoleucine; Male; Membrane Proteins; Mutation, Missense; Valine; White People | 2004 |
Double heterozygosity for a novel missense mutation of Ile304 to Asn in addition to the missense mutation His280 to Pro in the integrin beta3 gene as a cause of the absence of platelet alphaIIbbeta3 in Glanzmann's thrombasthenia.
Topics: Adult; Animals; Asparagine; Blotting, Western; COS Cells; DNA Primers; DNA, Complementary; Exons; Female; Flow Cytometry; Genetic Vectors; Heterozygote; Histidine; Humans; Immunoprecipitation; Integrin beta3; Isoleucine; Male; Mutation, Missense; Pedigree; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Thrombasthenia; Transfection | 2005 |
Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.
Topics: Alleles; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Isoleucine; Leucine; Neoplasm Proteins; Polymorphism, Single Nucleotide; Transfection; Tyrosine | 2005 |
Novel compound heterozygous mutations in the PANK2 gene in a Chinese patient with atypical pantothenate kinase-associated neurodegeneration.
Topics: Adult; Asian People; Asparagine; Aspartic Acid; DNA Mutational Analysis; Exons; Glycine; Heterozygote; Humans; Isoleucine; Magnetic Resonance Imaging; Male; Mutation; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor) | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Homology modeling based solution structure of Hoxc8-DNA complex: role of context bases outside TAAT stretch.
Topics: Amino Acid Sequence; Antennapedia Homeodomain Protein; Asparagine; Base Composition; Computer Simulation; Conserved Sequence; DNA; Glycine; Homeodomain Proteins; Humans; Hydrogen Bonding; Isoleucine; Kinetics; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Osteopontin; Promoter Regions, Genetic; Protein Structure, Secondary; Repressor Proteins; Sequence Homology, Amino Acid; Sialoglycoproteins; Solutions; Templates, Genetic; Transcription Factors; Water | 2005 |
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine | 2005 |
Pharmacological characterization of human and murine neuropeptide s receptor variants.
Topics: Amino Acid Sequence; Animals; Asparagine; Caco-2 Cells; Calcium; Cell Division; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Exons; Genes, Reporter; Genetic Variation; HT29 Cells; Humans; Isoleucine; Luciferases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuropeptides; Phosphorylation; Polymorphism, Genetic; Protein Isoforms; Radioligand Assay; Receptors, Neuropeptide; Structure-Activity Relationship | 2005 |
Glucocerebrosidase mutations are an important risk factor for Lewy body disorders.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Autopsy; Brain; DNA Mutational Analysis; Female; Glucosylceramidase; Humans; Isoleucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Risk Factors; Synucleins; Threonine | 2006 |
Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.
Topics: Asparagine; Escherichia coli; Fluorescence Resonance Energy Transfer; Gene Library; Isoleucine; Membrane Proteins; Models, Chemical; Models, Molecular; Mutation; Peptide Library; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Serine Endopeptidases; Substrate Specificity | 2007 |
Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Glutamine; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Protein Structure, Secondary; Valine; Xanthine | 2006 |
Molecular characterization of cold adaptation based on ortholog protein sequences from Vibrionaceae species.
Topics: Acclimatization; Alanine; Aliivibrio salmonicida; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacterial Proteins; Cold Temperature; Computational Biology; Databases, Genetic; Glutamine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Protein Conformation; Sequence Alignment; Surface Properties; Vibrionaceae | 2007 |
Dynamic association of the fragile X mental retardation protein as a messenger ribonucleoprotein between microtubules and polyribosomes.
Topics: Actins; Animals; Asparagine; Cell Line; Dendrites; Fragile X Mental Retardation Protein; Humans; Isoleucine; Kinetics; Methoxyhydroxyphenylglycol; Mice; Microtubules; Mutant Proteins; Mutation; Polyribosomes; Protein Transport; Rats; Receptors, Metabotropic Glutamate; Ribonucleases; Ribonucleoproteins | 2008 |
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Topics: Acetylcholinesterase; Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutamine; Isoleucine; Leucine; Mice; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Stereoisomerism; Terbutaline; Tyrosine | 2008 |
Cysteine-scanning analysis of putative helix XII in the YgfO xanthine permease: ILE-432 and ASN-430 are important.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Gene Expression Regulation, Bacterial; Inhibitory Concentration 50; Isoleucine; Kinetics; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Nucleobase Transport Proteins; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2008 |
SO-LAAO, a novel L-amino acid oxidase that enables Streptococcus oligofermentans to outcompete Streptococcus mutans by generating H2O2 from peptone.
Topics: Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Glutamine; Hydrogen Peroxide; Isoleucine; L-Amino Acid Oxidase; Molecular Sequence Data; Mutation; Peptones; Sequence Homology, Amino Acid; Streptococcus; Streptococcus mutans; Tryptophan | 2008 |
Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation.
Topics: Animals; Asparagine; Cell Line, Transformed; Cell Proliferation; Charcot-Marie-Tooth Disease; Cranial Nerve Diseases; Disease Models, Animal; Early Growth Response Protein 2; Humans; Immunoprecipitation; Isoleucine; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Myelin Proteins; Neoplasm Proteins; Neural Conduction; Ranvier's Nodes; Repressor Proteins; Schwann Cells; Sciatic Nerve | 2009 |
Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Asparagine; Female; Genetic Carrier Screening; Genotype; Humans; Isoleucine; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Presenilin-2 | 2010 |
Oligomerization of an archaeal group II chaperonin is mediated by N-terminal salt bridges.
Topics: Amino Acid Sequence; Archaeal Proteins; Asparagine; Chaperonins; Isoleucine; Molecular Sequence Data; Mutagenesis; Protein Structure, Tertiary; Pyrococcus furiosus | 2011 |
The functional coding variant Asn107Ile of the neuropeptide S receptor gene (NPSR1) is associated with schizophrenia and modulates verbal memory and the acoustic startle response.
Topics: Acoustic Stimulation; Adult; Algorithms; Amino Acid Substitution; Analysis of Variance; Asparagine; Blinking; Diagnostic and Statistical Manual of Mental Disorders; DNA; Female; Genotype; Humans; Isoleucine; Male; Memory; Neuropsychological Tests; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Sensory Gating | 2012 |
A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney-Stratakis dyad.
Topics: Adult; Amino Acid Substitution; Asparagine; Family; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Germ-Line Mutation; Humans; Isoleucine; Male; Middle Aged; Paraganglioma, Extra-Adrenal; Succinate Dehydrogenase | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Transfer RNA gene numbers may not be completely responsible for the codon usage bias in asparagine, isoleucine, phenylalanine, and tyrosine in the high expression genes in bacteria.
Topics: Asparagine; Bacterial Proteins; Codon; DNA-Directed RNA Polymerases; Gene Dosage; Genes, Bacterial; Genome, Bacterial; Isoleucine; Models, Genetic; Phenylalanine; Protein Biosynthesis; RNA, Bacterial; RNA, Transfer; Tyrosine | 2012 |
Importance of polarity of the α4-α5 loop residue-Asn(166) in the pore-forming domain of the Bacillus thuringiensis Cry4Ba toxin: implications for ion permeation and pore opening.
Topics: Aedes; Alanine; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Electric Conductivity; Endotoxins; Escherichia coli; Fluoresceins; Hemolysin Proteins; Ion Transport; Isoleucine; Larva; Liposomes; Models, Molecular; Molecular Sequence Data; Permeability; Pest Control, Biological; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment | 2014 |
Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: role of Asn181 and Ile335 validated by spectroscopic and computational studies.
Topics: Asparagine; Binding Sites; Flavin-Adenine Dinucleotide; Furans; Humans; Isoleucine; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Interaction Domains and Motifs; Spectrum Analysis; Structure-Activity Relationship | 2014 |
A serologic weakly reactive RhD is caused by a RHD 374T>A (Ile125Asn).
Topics: Amino Acid Substitution; Antigen-Antibody Reactions; Asparagine; Blood Donors; Humans; Isoleucine; Male; Polymorphism, Single Nucleotide; Rh-Hr Blood-Group System; Serologic Tests | 2015 |
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult | 2015 |
Serum metabolomic profile of incident diabetes.
Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Erythritol; Female; Glucose; Humans; Isoleucine; Lactic Acid; Leucine; Male; Maryland; Metabolome; Middle Aged; Minnesota; Mississippi; North Carolina; Prospective Studies; Risk Factors; Trehalose; Valine | 2018 |
Bilirubin Interference in Plasma Amino Acid Analysis by Ion Exchange Chromatography.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Bilirubin; Cellulose; Child, Preschool; Chromatography, Ion Exchange; Cross-Sectional Studies; Cystine; Female; Glycine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Tryptophan | 2018 |
Sex/Gender Modifies the Association Between the MC4R p.Ile269Asn Mutation and Type 2 Diabetes in the Mexican Population.
Topics: Adult; Aged; Amino Acid Substitution; Asparagine; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Effect Modifier, Epidemiologic; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Isoleucine; Male; Mexico; Middle Aged; Polymorphism, Single Nucleotide; Receptor, Melanocortin, Type 4; Risk Factors; Sex Factors | 2021 |
Biochemical impact of a disease-causing Ile67Asn substitution on BOLA3 protein.
Topics: Asparagine; Glutaredoxins; Humans; Isoleucine; Mitochondrial Diseases; Mitochondrial Proteins; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Multimerization | 2021 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Animal; Epilepsy; Glucose; Glutamates; Isoleucine; Ketone Bodies; Lactates; Leucine; Pentylenetetrazole; Pyruvates; Rats; Seizures; Succinates; Valine | 2022 |
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine | 2022 |
Unveiling the Essential Role of Arkadia's Non-RING Elements in the Ubiquitination Process.
Topics: Alanine; Arginine; Asparagine; Glutamine; Glycine; Isoleucine; Threonine; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.
Topics: Amino Acid Sequence; Asparagine; Dictyostelium; Histidine; Isoleucine; Leucine; Leucine-Rich Repeat Proteins; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Metabolomic profiling in kidney cells treated with a sodium glucose-cotransporter 2 inhibitor.
Topics: Arginine; Asparagine; Epithelial Cells; Glucose; Glutathione; Histidine; Humans; Isoleucine; Kidney; Lysine; Metabolomics; Methionine; Phenylalanine; Proline; Sodium; Sodium-Glucose Transporter 2; Threonine | 2023 |
Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Asparagine; Calcium; Cryoelectron Microscopy; Dihydropyridines; Isoleucine; Nitrogen Dioxide; Sodium Channels | 2023 |