Page last updated: 2024-08-26

isohumulone and cyclopentane

isohumulone has been researched along with cyclopentane in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's12 (60.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harder, DB; Whitney, G1
Budwig, C; Guinard, JX; Hong, DY; Russell, GF; Zoumas-Morse, C1
Andersen, ML; De Keukeleire, D; Heyerick, A; Huvaere, K; Olsen, K; Skibsted, LH1
Ezaki, O; Fujiwara, D; Ikeshima, E; Kanaya, T; Kondo, K; Odai, H; Oikawa, S; Shiraki, M; Tsuboyama-Kasaoka, N; Yajima, H1
Andersen, ML; De Keukeleire, D; Heyerick, A; Huvaere, K; Skibsted, LH1
Ezaki, O; Ikeshima, E; Kanaya, T; Kondo, K; Noguchi, T; Oikawa, S; Shiraki, M; Tsuboyama-Kasaoka, N; Yajima, H1
De Keukeleire, D; Forbes, MD; Heyerick, A; Huvaere, K1
Hosono, M; Kondo, K; Miura, Y; Odai, H; Oikawa, S; Oyamada, C1
Kondo, K; Nakao, W; Nozawa, H; Zhao, F1
Hasumi, A; Hosono, M; Kondo, K; Minato, T; Miura, Y; Mizutani, S; Oikawa, S; Shimura, M; Yoshida, A1
Gänzle, MG; Schwab, C1
Nguyen, T; Pozdrik, R; Roddick, FA; Rogers, PJ1
Fujimoto, S; Haruna, Y; Kashihara, N; Komai, N; Namikoshi, T; Ohzeki, M; Sasaki, T; Tomita, N; Yoshida, A1
Hitomi, Y; Kondo, K; Mizutani, M; Obara, K; Yajima, H1
Dunkel, A; Haseleu, G; Hofmann, T; Intelmann, D; Lagemann, A; Stephan, A1
Boussery, K; Bracke, M; Cattoor, K; De Keukeleire, D; Deforce, D; Heyerick, A; Remon, JP; Van Bocxlaer, J1
Blanco, CA; Caballero, I; Nimubona, D1
Berger, R; Böhme, S; Glomb, MA; Rakete, S1
Akasaka, T; Fujimoto, S; Kashihara, N; Mochizuki, S; Tanimoto, M; Tomita, J; Yoshida, K1
Albert, V; Behrens, M; Bland, JS; Fang, M; Galmozzi, A; Godio, C; Grayson, N; Kim, SM; Kim, W; Kok, BP; Littlejohn, NK; Meyerhof, W; Saez, E; Siuzdak, G; Srinivasan, S1

Trials

3 trial(s) available for isohumulone and cyclopentane

ArticleYear
Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Aged; Animals; Blood Glucose; Body Weight; Cyclopentanes; Diabetes Mellitus, Type 2; Dietary Fats; DNA-Binding Proteins; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glycated Hemoglobin; Humans; Humulus; Insulin Resistance; Lipoprotein Lipase; Male; Mice; Mice, Inbred C57BL; Middle Aged; Pilot Projects; Pioglitazone; Placebos; Plant Extracts; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Thiazolidinediones; Transcription Factors; Transfection; Triglycerides; Weight Gain

2004
Isohumulones, the bitter component of beer, improve hyperglycemia and decrease body fat in Japanese subjects with prediabetes.
    Clinical nutrition (Edinburgh, Scotland), 2009, Volume: 28, Issue:3

    Topics: Adipose Tissue; Adult; Aged; Anthropometry; Anti-Obesity Agents; Beer; Blood Glucose; Body Composition; Body Mass Index; Capsules; Cyclopentanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Obesity; Tomography, X-Ray Computed; Treatment Outcome

2009
Acute improvement of endothelial functions after oral ingestion of isohumulones, bitter components of beer.
    Biochemical and biophysical research communications, 2017, Mar-18, Volume: 484, Issue:4

    Topics: Administration, Oral; Adult; Alcoholic Beverages; Beer; Cells, Cultured; Cross-Over Studies; Cyclopentanes; Double-Blind Method; Eating; Endothelial Cells; Humans; Humulus; Male; Nitric Oxide; Plant Extracts; Smoking

2017

Other Studies

17 other study(ies) available for isohumulone and cyclopentane

ArticleYear
Genetics of bitter perception in mice.
    Physiology & behavior, 1994, Volume: 56, Issue:6

    Topics: Animals; Chromosome Mapping; Cyclohexenes; Cyclopentanes; Dose-Response Relationship, Drug; Female; Food Preferences; Male; Mice; Mice, Inbred Strains; Phenotype; Phenylthiourea; Quaternary Ammonium Compounds; Species Specificity; Strychnine; Sucrose; Synaptic Transmission; Taste; Taste Buds; Taste Threshold; Terpenes

1994
Chemoreception and perception of the bitterness of isohumulones.
    Physiology & behavior, 1994, Volume: 56, Issue:6

    Topics: Adolescent; Adult; Beer; Cyclopentanes; Dose-Response Relationship, Drug; Female; Humans; Male; Psychophysiology; Salivation; Taste; Taste Buds; Taste Threshold

1994
Radicaloid-type oxidative decomposition of beer bittering agents revealed.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2003, Oct-06, Volume: 9, Issue:19

    Topics: Beer; Cyclopentanes; Electron Spin Resonance Spectroscopy; Flavoring Agents; Free Radicals; Humulus; Oxidation-Reduction; Taste

2003
Photooxidative degradation of beer bittering principles: a key step on the route to lightstruck flavor formation in beer.
    Journal of agricultural and food chemistry, 2005, Mar-09, Volume: 53, Issue:5

    Topics: Beer; Cyclopentanes; Light; Oxidation-Reduction; Photochemistry; Taste

2005
Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents.
    International journal of obesity (2005), 2005, Volume: 29, Issue:8

    Topics: Animals; Base Sequence; Cyclopentanes; Diet; Dietary Supplements; Feces; Gene Expression; Glucose Tolerance Test; Insulin Resistance; Lipase; Lipid Metabolism; Lipids; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Obesity; Phytotherapy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Triglycerides

2005
Fate of flavins in sensitized photodegradation of isohumulones and reduced derivatives: studies on formation of radicals via EPR combined with detailed product analyses.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2005, Volume: 4, Issue:5

    Topics: Cyclopentanes; Electron Spin Resonance Spectroscopy; Flavins; Free Radicals; Microwaves; Molecular Conformation; Oxidation-Reduction; Photochemistry; Photolysis; Sensitivity and Specificity

2005
Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents similar to PPARalpha activations in C57BL/6 mice.
    The British journal of nutrition, 2005, Volume: 93, Issue:4

    Topics: Acyl-CoA Oxidase; Animals; Arteriosclerosis; Beer; Cholesterol; Cholesterol, HDL; Coenzyme A Ligases; Cyclopentanes; Dietary Fats; Dose-Response Relationship, Drug; Fatty Acid Transport Proteins; Female; Gene Expression; Hydroxymethylglutaryl-CoA Synthase; Lipoprotein Lipase; Liver; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; PPAR alpha; RNA, Messenger; Triglycerides

2005
Dietary supplement of isohumulones inhibits the formation of aberrant crypt foci with a concomitant decrease in prostaglandin E2 level in rat colon.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:8

    Topics: Animals; Azoxymethane; Beer; Carcinogens; Cell Line; Colon; Colonic Neoplasms; Cyclopentanes; Dietary Supplements; Dinoprostone; Interferon-gamma; Intestinal Mucosa; Ionophores; Lipopolysaccharides; Macrophages; Male; Mice; Precancerous Conditions; Rats; Rats, Inbred F344

2005
Isohumulones modulate blood lipid status through the activation of PPAR alpha.
    Biochimica et biophysica acta, 2005, Sep-05, Volume: 1736, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Animals; Carbon-Carbon Double Bond Isomerases; Cyclopentanes; Dose-Response Relationship, Drug; Enoyl-CoA Hydratase; Female; Gene Expression Profiling; Gene Expression Regulation; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; PPAR alpha; Racemases and Epimerases; Sex Factors

2005
Effect of membrane lateral pressure on the expression of fructosyltransferases in Lactobacillus reuteri.
    Systematic and applied microbiology, 2006, Volume: 29, Issue:2

    Topics: Cyclopentanes; Fructans; Hexosyltransferases; Ionophores; Limosilactobacillus reuteri; Nigericin; Oligosaccharides; Temperature; Tenuazonic Acid

2006
Spectrophotometric method for exploring 3-methyl-2-butene-1-thiol (MBT) formation in lager.
    Journal of agricultural and food chemistry, 2006, Aug-23, Volume: 54, Issue:17

    Topics: Ascorbic Acid; Beer; Butanes; Catechin; Cyclopentanes; Indoles; Light; Photochemistry; Riboflavin; Spectrophotometry; Sulfhydryl Compounds

2006
Isohumulones derived from hops ameliorate renal injury via an anti-oxidative effect in Dahl salt-sensitive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Blood Pressure; Blotting, Western; Cyclopentanes; Humulus; Hypertension; Kidney Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Proteinuria; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium Chloride; Tyrosine

2007
Comprehensive sensomics analysis of hop-derived bitter compounds during storage of beer.
    Journal of agricultural and food chemistry, 2011, Mar-09, Volume: 59, Issue:5

    Topics: Beer; Chromatography, Liquid; Cyclopentanes; Food Preservation; Humulus; Sensation; Tandem Mass Spectrometry; Taste

2011
Bioavailability of hop-derived iso-α-acids and reduced derivatives.
    Food & function, 2011, Volume: 2, Issue:7

    Topics: Animals; Biological Availability; Caco-2 Cells; Cyclohexenes; Cyclopentanes; Humans; Humulus; Intestinal Absorption; Rabbits; Terpenes

2011
Prediction of the ageing of commercial lager beer during storage based on the degradation of iso-α-acids.
    Journal of the science of food and agriculture, 2014, Volume: 94, Issue:10

    Topics: Acids; Beer; Chromatography, High Pressure Liquid; Cyclopentanes; Diterpenes; Food Storage; Humans; Humulus; Isomerism; Taste

2014
Oxidation of isohumulones induces the formation of carboxylic acids by hydrolytic cleavage.
    Journal of agricultural and food chemistry, 2014, Jul-30, Volume: 62, Issue:30

    Topics: Amides; Beer; Carboxylic Acids; Chromatography, Liquid; Cyclopentanes; Hydrolysis; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Proline; Tandem Mass Spectrometry

2014
Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits.
    Molecular metabolism, 2018, Volume: 16

    Topics: Animals; Body Weight; Cyclopentanes; Diabetes Mellitus, Type 2; Disease Models, Animal; Enteroendocrine Cells; Glucagon-Like Peptide 1; Humulus; Hypoglycemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, G-Protein-Coupled; Signal Transduction

2018