isoguvacine and muscimol

isoguvacine has been researched along with muscimol in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (65.00)	18.7374
1990's	7 (17.50)	18.2507
2000's	6 (15.00)	29.6817
2010's	1 (2.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bang-Andersen, B; Ebert, B; Frølund, B; Hansen, CP; Jensen, AA; Kristiansen, U; Krogsgaard-Larsen, P; Larsen, M; Liljefors, T; Madsen, C; Nielsen, B	1
Balle, T; Bergmann, R; Damgaard, M; Frølund, B; Jensen, AA; Nielsen, B; Petersen, JG; Sørensen, T	1
Bowery, NG; Collins, JF; Hudson, AL; Neal, MJ	1
Polc, P	1
Karobath, M; Lippitsch, M	1
Curtis, DR; Johnston, GA; Lodge, D	1
Conzelmann, U; Meyer, DK; Müller, A	1
Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S	1
Hablitz, JJ; Mistry, DK	1
Balcar, VJ	1
Oveissi, Y; Zarrindast, MR	1
Crawford, ML; Young, JM	1
Olsen, RW; Snowman, AM	1
Iversen, LL; Wong, EH	1
Allan, AM; Harris, RA	1
Ciesielski, L; Gobaille, S; Mandel, P; Molina, V	1
Kemp, JA; Marshall, GR; Woodruff, GN	1
Anderson, R; Mitchell, R	1
Audi, EA; Brandão, ML; Graeff, FG; Schütz, MT	1
Astier, H; Roussel, JP; Tapia-Arancibia, L	1
Ben-Ari, Y; Cherubini, E; Rovira, C	1
Brown, DA; Scholfield, CN	1
Meldrum, B	1
Desarmenien, M; Feltz, P; Headley, PM	1
Mantegazza, P; Tammiso, R; Vicentini, L; Zambotti, F; Zonta, N	2
Falch, E; Krogsgaard-Larsen, P	1
Brehm, L; Krogsgaard-Larsen, P; Schaumburg, K	1
Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R	1
Agardh, E; Ehinger, B	1
Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ	1
Bloch, R; Bousquet, P; Feldman, J; Schwartz, J	1
Chen, DZ; Chen, SH; Katsura, M; Kuriyama, K; Ohkuma, S	1
Guan, BC; Hu, HZ; Li, ZW; Si, JQ; Zhou, XP	1
Bas, DE; Calamera, JC; Ritta, MN	1
Buckingham, SD; Hosie, AM; Presnail, JK; Sattelle, DB	1
Ebert, B; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T	1
Denda, M; Denda, S; Inomata, S; Inoue, K	1
Bjerrum, OJ; Blackburn-Munro, G; Jensen, DG; Rode, F	1
Calandra, RS; Doepner, RF; Fohr, K; Frungieri, MB; Geigerseder, C; Gonzalez-Calvar, SI; Kunz, L; Mayerhofer, A; Raemsch, R	1

Reviews

4 review(s) available for isoguvacine and muscimol

Article	Year
GABA-agonists as anti-epileptic agents. Advances in biochemical psychopharmacology, 1981, Volume: 26 Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Disease Models, Animal; Epilepsy; Etomidate; gamma-Aminobutyric Acid; Hydroxybutyrates; Isonicotinic Acids; Mice; Muscimol; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Oxybate	1981
GABA agonists. Development and interactions with the GABA receptor complex. Molecular and cellular biochemistry, 1981, Aug-11, Volume: 38 Spec No, Issue:Pt 1 Topics: Amino Acids; Animals; Benzodiazepines; Brain Chemistry; Cats; Chemical Phenomena; Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Mice; Models, Structural; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship	1981
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure. Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, Volume: 35, Issue:5 Topics: Agaricales; Amanita; Animals; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Structural; Molecular Conformation; Muscimol; Nipecotic Acids; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism	1981
GABA(A) receptor ligands and their therapeutic potentials. Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8 Topics: Animals; Central Nervous System Diseases; GABA Agents; GABA Agonists; GABA Antagonists; Humans; Isonicotinic Acids; Isoxazoles; Ligands; Muscimol; Piperidines; Protein Subunits; Receptors, GABA-A	2002

Other Studies

36 other study(ies) available for isoguvacine and muscimol

Article	Year
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists. Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17 Topics: Animals; Brain; Cell Line; GABA Agonists; GABA-A Receptor Agonists; Humans; Imidazoles; In Vitro Techniques; Ligands; Membrane Potentials; Models, Molecular; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Radioligand Assay; Rats; Receptors, GABA; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship	2007
Synthesis and pharmacological evaluation of 6-aminonicotinic acid analogues as novel GABA(A) receptor agonists. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Humans; Ligands; Models, Molecular; Molecular Structure; Niacin; Receptors, GABA-A; Structure-Activity Relationship	2014
Isoguvacine, isonipecotic acid, muscimol and N-methyl isoguvacine on the GABA receptor in rat sympathetic ganglia. Experientia, 1978, Sep-15, Volume: 34, Issue:9 Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Autonomic; Isonicotinic Acids; Isonipecotic Acids; Membrane Potentials; Muscimol; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship	1978
Effects of GABA-mimetic agents on the cat spinal cord. Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4 Topics: Animals; Bicuculline; Cats; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Ibotenic Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neurons, Afferent; Spinal Cord	1979
THIP and isoguvacine are partial agonists of GABA-stimulated benzodiazepine receptor binding. European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4 Topics: Animals; Benzodiazepines; Cerebral Cortex; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Drug	1979
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord. Journal of neurochemistry, 1978, Volume: 31, Issue:6 Topics: Aminobutyrates; Animals; Biological Transport; Cats; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons; Nipecotic Acids; Oxazoles; Spinal Cord	1978
Effects of GABA receptor stimulation on the release of [3H]GABA from slices of rat neostriatum. Life sciences, 1992, Volume: 50, Issue:13 Topics: Animals; Convulsants; Corpus Striatum; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Channels; Tetrodotoxin	1992
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures. Psychopharmacology, 1991, Volume: 104, Issue:3 Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid	1991
Activation of subconductance states by gamma-aminobutyric acid and its analogs in chick cerebral neurons. Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:4 Topics: Analgesics; Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons	1990
Presence of a highly efficient "binding" to bacterial contamination can distort data from binding studies. Neurochemical research, 1990, Volume: 15, Issue:12 Topics: Animals; Cats; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Gram-Positive Bacteria; Isonicotinic Acids; Muscimol; Nipecotic Acids; Proline; Pyridazines; Radioligand Assay; Receptors, GABA-A; Tritium	1990
GABAA and GABAB receptor sites involvement in rat thermoregulation. General pharmacology, 1988, Volume: 19, Issue:2 Topics: Animals; Baclofen; Bicuculline; Body Temperature Regulation; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Isonicotinic Acids; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A	1988
GABAB receptor-mediated inhibition of histamine H1-receptor-induced inositol phosphate formation in slices of rat cerebral cortex. Journal of neurochemistry, 1988, Volume: 51, Issue:5 Topics: Animals; Baclofen; Carbachol; Cerebral Cortex; gamma-Aminobutyric Acid; Histamine; Inositol; Inositol Phosphates; Isonicotinic Acids; Kinetics; Lithium; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Histamine H1; Sugar Phosphates	1988
Avermectin B1a modulation of gamma-aminobutyric acid/benzodiazepine receptor binding in mammalian brain. Journal of neurochemistry, 1985, Volume: 44, Issue:4 Topics: Animals; Bicuculline; Brain; Cattle; Cell Membrane; Cerebral Cortex; Etazolate; gamma-Aminobutyric Acid; Isonicotinic Acids; Ivermectin; Lactones; Muscimol; Pentobarbital; Rats; Receptors, GABA-A	1985
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists. Journal of neurochemistry, 1985, Volume: 44, Issue:4 Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine	1985
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes. Molecular pharmacology, 1986, Volume: 29, Issue:5 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature	1986
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3 Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin	1986
Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation. British journal of pharmacology, 1986, Volume: 87, Issue:4 Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A	1986
Biphasic effect of GABAA receptor agonists on prolactin secretion: evidence for two types of GABAA receptor complex on lactotrophes. European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2 Topics: Animals; Baclofen; Carnosine; Isonicotinic Acids; Male; Muscimol; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A	1986
Modulation of the brain aversive system by GABAergic and serotonergic mechanisms. Behavioural brain research, 1986, Volume: 21, Issue:1 Topics: Animals; Avoidance Learning; Benzodiazepines; Cerebral Ventricles; Chlordiazepoxide; Drug Interactions; gamma-Aminobutyric Acid; Isonicotinic Acids; Midazolam; Muscimol; Pentobarbital; Periaqueductal Gray; Rats; Receptors, GABA-A; Serotonin	1986
Evidence for a dual effect of gamma-aminobutyric acid on thyrotropin (TSH)-releasing hormone-induced TSH release from perifused rat pituitaries. Endocrinology, 1987, Volume: 121, Issue:3 Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone	1987
Somatic and dendritic actions of gamma-aminobutyric acid agonists and uptake blockers in the hippocampus in vivo. Neuroscience, 1984, Volume: 12, Issue:2 Topics: Acetylcholine; Action Potentials; Animals; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Synaptic Transmission	1984
Inhibition of GABA uptake potentiates the conductance increase produced by GABA-mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea-pig. British journal of pharmacology, 1984, Volume: 83, Issue:1 Topics: Animals; Central Nervous System; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isonicotinic Acids; Muscimol; Neural Conduction; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Olfactory Pathways; Proline; Sodium; Taurine	1984
Does glial uptake affect GABA responses? AN intracellular study on rat dorsal root ganglion neurones in vitro. The Journal of physiology, 1980, Volume: 307 Topics: Animals; beta-Alanine; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Isonicotinic Acids; Membrane Potentials; Muscimol; Neuroglia; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A	1980
Effects of some GABA-mimetic drugs on the antinociceptive activity of morphine and beta-endorphin in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:3 Topics: Analgesics; Animals; beta-Endorphin; Bicuculline; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Morphine; Muscimol; Nicotinic Acids; Nipecotic Acids; Rats	1981
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue. The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:3 Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A	1982
(3H)-muscimol, (3H)-nipecotic acid and (3H)-isoguvacine as autoradiographic markers for GABA neurotransmission. Journal of neural transmission, 1982, Volume: 54, Issue:1-2 Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Goldfish; Guinea Pigs; Isonicotinic Acids; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Oxazoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission	1982
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine. Journal of neurochemistry, 1982, Volume: 39, Issue:5 Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship	1982
Pharmacological analysis of the central cardiovascular effects of four GABA analogues. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:4 Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1984
The effect of GABAergic agents on opiate analgesia. Pharmacological research communications, 1980, Volume: 12, Issue:3 Topics: Animals; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Injections, Intraventricular; Isonicotinic Acids; Male; Morphine; Muscimol; Narcotics; Nicotinic Acids; Nipecotic Acids; Pain; Rats; Reaction Time; Time Factors	1980
GABAA receptor stimulation enhances NMDA-induced Ca2+ influx in mouse cerebral cortical neurons in primary culture. Brain research. Molecular brain research, 1994, Volume: 27, Issue:1 Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Chloride Channels; Dizocilpine Maleate; Dose-Response Relationship, Drug; GABA Agonists; Isonicotinic Acids; Mice; Muscimol; N-Methylaspartate; Neurons; Picrotoxin; Potassium; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	1994
Inhibitory effect of baclofen on GABA-induced depolarization and GABA-activated current in primary sensory neurons. Neuroscience, 1997, Volume: 81, Issue:3 Topics: Animals; Baclofen; Electric Conductivity; Electrophysiology; Female; GABA Agonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Muscimol; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Time Factors	1997
Occurrence of GABA and GABA receptors in human spermatozoa. Molecular human reproduction, 1998, Volume: 4, Issue:8 Topics: Bicuculline; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Male; Muscimol; Receptors, GABA; Semen; Sperm Motility; Spermatozoa; Tritium	1998
Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency. Neuroscience, 2001, Volume: 102, Issue:3 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Exons; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Library; Genetic Variation; In Vitro Techniques; Isonicotinic Acids; Isonipecotic Acids; Membrane Potentials; Molecular Sequence Data; Muscimol; Oocytes; Patch-Clamp Techniques; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Sulfonic Acids; Xenopus laevis	2001
gamma-Aminobutyric acid (A) receptor agonists accelerate cutaneous barrier recovery and prevent epidermal hyperplasia induced by barrier disruption. The Journal of investigative dermatology, 2002, Volume: 119, Issue:5 Topics: Animals; Baclofen; Epidermis; GABA Agonists; GABA-A Receptor Agonists; Humidity; Hyperplasia; Isonicotinic Acids; Male; Mice; Mice, Hairless; Muscimol; Receptors, GABA-A; Wound Healing	2002
Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain. European journal of pharmacology, 2005, Jun-01, Volume: 516, Issue:2 Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neuralgia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stress, Mechanical; Time Factors; Trauma, Nervous System; Zolpidem	2005
Insights into GABA receptor signalling in TM3 Leydig cells. Neuroendocrinology, 2005, Volume: 81, Issue:6 Topics: Animals; Blotting, Western; Calcium Signaling; Cell Line; Chloride Channels; Cyclic AMP; DNA, Complementary; Early Growth Response Protein 1; GABA Agonists; Gene Expression Regulation; Immunohistochemistry; Isonicotinic Acids; Leydig Cells; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscimol; Oligonucleotide Array Sequence Analysis; Patch-Clamp Techniques; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA; Second Messenger Systems; Signal Transduction; Spectrometry, Fluorescence; Testis	2005