isoguvacine has been researched along with isoxazoles in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Polc, P | 1 |
| Karobath, M; Lippitsch, M | 1 |
| Curtis, DR; Johnston, GA; Lodge, D | 1 |
| Falch, E; Kristiansen, U; Krogsgaard-Larsen, P; Lambert, JD | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S | 1 |
| Hablitz, JJ; Mistry, DK | 1 |
| Balcar, VJ; Dreher, B | 1 |
| Iversen, LL; Wong, EH | 1 |
| Hösli, E; Hösli, L; Krogsgaard-Larsen, P | 1 |
| Allan, AM; Harris, RA | 1 |
| Ciesielski, L; Gobaille, S; Mandel, P; Molina, V | 1 |
| Ben-Ari, Y; Cherubini, E; Rovira, C | 1 |
| Karobath, M; Supavilai, P | 1 |
| Benson, DI; Klepner, CA; Squires, RF | 1 |
| Aaes-Jørgensen, T; Bøgesø, KP; Krogsgaard-Larsen, P; Mikkelsen, H; Schultz, B | 1 |
| Brehm, L; Krogsgaard-Larsen, P; Schaumburg, K | 1 |
| Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R | 1 |
| Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ | 1 |
| Bloch, R; Bousquet, P; Feldman, J; Schwartz, J | 1 |
| Damgaard, I; Elster, L; Kardos, J; Krogsgaard-Larsen, P; Schousboe, A | 1 |
| Barnes, EM; Calkin, PA | 1 |
| Kristiansen, U; Lambert, JD | 1 |
| Firestone, LL; Hammond, DL; Homanics, GE; Ugarte, SD | 1 |
| Ebert, B; Fjalland, B; Hansen, SL; Kristiansen, U | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Ebert, B; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T | 1 |
| Bjerrum, OJ; Blackburn-Munro, G; Jensen, DG; Rode, F | 1 |
3 review(s) available for isoguvacine and isoxazoles
| Article | Year |
|---|---|
THIP, isoguvacine, isoguvacine oxide, and related GABA agonists.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Oxazoles; Pipecolic Acids; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution | 1981 |
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure.
Topics: Agaricales; Amanita; Animals; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Structural; Molecular Conformation; Muscimol; Nipecotic Acids; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1981 |
GABA(A) receptor ligands and their therapeutic potentials.
Topics: Animals; Central Nervous System Diseases; GABA Agents; GABA Agonists; GABA Antagonists; Humans; Isonicotinic Acids; Isoxazoles; Ligands; Muscimol; Piperidines; Protein Subunits; Receptors, GABA-A | 2002 |
24 other study(ies) available for isoguvacine and isoxazoles
| Article | Year |
|---|---|
Effects of GABA-mimetic agents on the cat spinal cord.
Topics: Animals; Bicuculline; Cats; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Ibotenic Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neurons, Afferent; Spinal Cord | 1979 |
THIP and isoguvacine are partial agonists of GABA-stimulated benzodiazepine receptor binding.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Drug | 1979 |
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord.
Topics: Aminobutyrates; Animals; Biological Transport; Cats; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons; Nipecotic Acids; Oxazoles; Spinal Cord | 1978 |
Electrophysiological studies of the GABAA receptor ligand, 4-PIOL, on cultured hippocampal neurones.
Topics: Animals; Bicuculline; Cells, Cultured; Female; Hippocampus; Isonicotinic Acids; Isoxazoles; Membrane Potentials; Neurons; Piperidines; Pregnancy; Rats; Receptors, GABA-A; Spinal Cord | 1991 |
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid | 1991 |
Activation of subconductance states by gamma-aminobutyric acid and its analogs in chick cerebral neurons.
Topics: Analgesics; Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons | 1990 |
Neurochemical correlates of gamma-aminobutyrate (GABA) inhibition in cat visual cortex.
Topics: Animals; Baclofen; Calcium; Cats; Cell Membrane; Female; GABA Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Neurons; Potassium; Pyridazines; Receptors, GABA-A; Visual Cortex | 1990 |
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine | 1985 |
Autoradiographic localization of binding sites for the gamma-aminobutyric acid analogues 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP)isoguvacine and baclofen on cultured neurons of rat cerebellum and spinal cord.
Topics: Animals; Animals, Newborn; Autoradiography; Baclofen; Binding Sites; Cells, Cultured; Cerebellum; Fetus; Isonicotinic Acids; Isoxazoles; Oxazoles; Rats; Receptors, GABA-A; Spinal Cord | 1985 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin | 1986 |
Somatic and dendritic actions of gamma-aminobutyric acid agonists and uptake blockers in the hippocampus in vivo.
Topics: Acetylcholine; Action Potentials; Animals; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Synaptic Transmission | 1984 |
The effect of temperature and chloride ions on the stimulation of [3H]flunitrazepam binding by the muscimol analogues THIP and piperidine-4-sulfonic acid.
Topics: Animals; Anti-Anxiety Agents; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Oxazoles; Piperidines; Rats; Stimulation, Chemical; Temperature; Tritium | 1980 |
Multiple benzodiazepine receptor complexes: some benzodiazepine recognition sites are coupled to GABA receptors and ionophores.
Topics: Animals; Anions; Benzodiazepines; Bicuculline; Brain; Buffers; Flunitrazepam; gamma-Aminobutyric Acid; Haplorhini; Hot Temperature; Ionophores; Isonicotinic Acids; Isoxazoles; Macromolecular Substances; Papio; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.
Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship | 1982 |
Pharmacological analysis of the central cardiovascular effects of four GABA analogues.
Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Role of GABAB receptors in intracellular Ca2+ homeostasis and possible interaction between GABAA and GABAB receptors in regulation of transmitter release in cerebellar granule neurons.
Topics: Animals; Aspartic Acid; Baclofen; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; GABA Agonists; GTP-Binding Proteins; Homeostasis; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Neurotransmitter Agents; Pertussis Toxin; Receptors, GABA-A; Receptors, GABA-B; Virulence Factors, Bordetella | 1994 |
gamma-Aminobutyric acid-A (GABAA) agonists down-regulate GABAA/benzodiazepine receptor polypeptides from the surface of chick cortical neurons.
Topics: Androstanes; Animals; Azasteroids; Blotting, Western; Cells, Cultured; Cerebral Cortex; Chick Embryo; Down-Regulation; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Molecular Weight; Neurons; Receptors, GABA-A | 1994 |
Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABAA receptor partial agonist, 4-PIOL.
Topics: Animals; Barbiturates; Benzodiazepines; Carbolines; Cells, Cultured; Convulsants; Electrophysiology; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Hippocampus; Hypnotics and Sedatives; Isonicotinic Acids; Isoxazoles; Membrane Potentials; Midazolam; Neurons; Patch-Clamp Techniques; Pentobarbital; Piperidines; Rats | 1996 |
Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor.
Topics: Animals; Baclofen; GABA Agonists; Hot Temperature; Injections, Spinal; Injections, Subcutaneous; Isonicotinic Acids; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nociceptors; Physical Stimulation; Protein Isoforms; Receptors, GABA-A; Sensory Thresholds; Sex Characteristics | 2000 |
Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Cerebral Cortex; Electrophysiology; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Oocytes; Patch-Clamp Techniques; Piperidines; Pyridazines; Receptors, GABA-A; Xenopus laevis | 2001 |
Potentiation of GABA(A) receptor agonists by GABA uptake inhibitors in the rat ventral midbrain.
Topics: Animals; Carrier Proteins; Drug Synergism; Electrophysiology; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mesencephalon; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Organic Anion Transporters; Oximes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium; Suprachiasmatic Nucleus | 2001 |
Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neuralgia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stress, Mechanical; Time Factors; Trauma, Nervous System; Zolpidem | 2005 |