isoflurophate has been researched along with serine in 113 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 85 (75.22) | 18.7374 |
1990's | 14 (12.39) | 18.2507 |
2000's | 13 (11.50) | 29.6817 |
2010's | 1 (0.88) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ibañez, IB; Markley, JL; Porubcan, MA; Westler, WM | 1 |
Rosenberg, RD | 1 |
Robbins, KC; Summaria, L | 1 |
Poste, G | 1 |
Dugas, H; Gaudet, F; Leduc, P | 1 |
Kolattukudy, PE; Purdy, RE | 2 |
Bendtzen, K | 2 |
Danø, K; Reich, E | 1 |
Grahn, DT; Kerr, MA; Neurath, H; Walsh, KA | 1 |
Heck, LW; Remold, HG; Remold-O'Donnell, E | 1 |
Chmielewska, I; Kowalska-Loth, B; Kurecki, T; Toczko, K | 1 |
Bedord, CJ; Buchner, JS; Kolattukudy, PE | 1 |
Krueger, JK; Schutt, CE; Stock, J | 1 |
Chen, L; Hsi, KL; Yuan, PM; Zieske, LR | 1 |
Bailey, CJ; Redpath, MB | 1 |
Fielding, CJ; Francone, OL | 1 |
Bailey, CJ; Smith, TP | 1 |
Abouakil, N; Lombardo, D; Rogalska, E | 1 |
Lauro, AM; Muster, T; Palese, P; Powers, JC; Vlasak, R | 1 |
Hayes, BK; Varki, A | 1 |
Kanagawa, K; Mitamura, T; Negoro, S; Oka, K; Okada, H | 1 |
Chatonnet, A; Masson, P | 1 |
Doctor, BP; Rush, RS; Wolfe, AD | 1 |
Blacher, RW; Naggert, J; Randhawa, ZI; Smith, S | 1 |
Beyreuther, K; Herrler, G; Klenk, HD; Multhaup, G | 1 |
Jany, KD; Mayer, B | 1 |
Fass, DN; Heldebrant, CM; Mann, KG; Yip, R | 1 |
Burt, AM; Silver, A | 1 |
Austen, KF | 1 |
Bauer, CA; Löfqvist, B | 1 |
Groskopf, WR; Hsieh, B; Robbins, KC; Summaria, L | 1 |
Groskopf, WR; Robbins, KC; Summaria, L | 1 |
Finley, EZ; Hirschowitz, BI; Sachs, G; Tsuji, T | 1 |
Davie, EW; Ericsson, LH; Fujikawa, K; Hermodson, MA; Neurath, H; Titani, K; Walsh, KA | 1 |
Cohen, AB | 1 |
Hsia, JC; Kosman, DJ; Piette, LH | 1 |
Gaucher, GM; Roche, RS; Voordouw, G | 1 |
Carson, JH; Gerber, AC; Hadorn, B | 1 |
Morihara, K; Oka, T; Tsuzuki, H | 1 |
Awad, WM; Ochoa, MS; Toomey, TP | 1 |
Goldberg, AL; Prouty, WF | 1 |
Shaw, DC; Wells, JR | 2 |
Hayashi, R; Moore, S; Stein, WH | 1 |
Becker, EL; David, JR | 1 |
Awad, WM; Bernstrom, GG; Ochoa, MS; Siegel, S; Skiba, WE; Soto, AR | 1 |
van Heyningen, S | 1 |
Davie, EW; Fujikawa, K; Legaz, ME | 1 |
Gates, BJ; Travis, J | 1 |
Bajaj, SP; Butkowski, RJ; Heldebrant, CM; Mann, KG | 1 |
Gordon, S; Reich, E; Unkeless, JC | 1 |
Collins, JP; Jones, JG | 1 |
Kramer, KJ; Law, JH; Miller, JW | 1 |
Biedler, JL; Wachsman, JT | 1 |
Mikes, O; Sorm, F; Toan, NB; Turková, J | 1 |
Millet, J | 1 |
Krisch, K | 1 |
Coan, MH; Roberts, RC; Travis, J | 1 |
Merkel, JR; Sipos, T | 1 |
Charles, M; Desnuelle, P; Maylié, MF | 1 |
Livingston, DM; Riordan, JF | 1 |
Movat, HZ; Ozge-Anwar, AH; Soltay, MJ | 1 |
Basford, JM; Collins, JP; Jones, JG | 1 |
Barnard, EA; Kawiak, J; Komender, J; Vensel, WH | 1 |
Bodlaender, P; Feinstein, G; Shaw, E | 1 |
Fiedler, F; Müller, B; Werle, E | 1 |
Halme, J; Kivirikko, KI; Simons, K | 1 |
Behnke, WD; Neurath, H; Wade, RD | 1 |
Houston, LL; Walsh, KA | 1 |
Clark, JF; Jakoby, WB | 1 |
Johnson, P; Smillie, LB | 1 |
Engström, L; Wählby, S | 1 |
Wählby, S | 1 |
de Haas, GH; Nieuwenhuizen, W; Postema, NM; van Deenen, LL | 1 |
Boublík, M; Gancev, MK; Turková, J | 1 |
Esnouf, MP; Leveson, JE | 1 |
Engström, L; von Hofsten, B; Wählby, S | 1 |
Lawrence, RC | 1 |
Roy, C; Whitaker, DR | 1 |
Boulanger, P; Devaux, C | 1 |
Kishi, H; Kishimoto, S; Kishimoto, T; Miki, Y; Muraguchi, A; Yamamura, Y | 1 |
Kolattukudy, PE; Poulose, AJ; Rogers, L | 1 |
Muszyńska, G; Wojtczak, M | 1 |
Gabel, BR; Koschinsky, MI | 1 |
Keiler, KC; Sauer, RT | 1 |
Herrler, G; Klenk, HD; Pleschka, S | 1 |
Bolgar, M; Colonno, RJ; DiIanni, CL; O'Boyle, DR; Stevens, JT; Weinheimer, SP | 1 |
Healy, MJ; Myers, MA; Oakeshott, JG | 1 |
Merrifield, RB; Unson, CG | 1 |
Jendrossek, D; Nojiri, M; Saito, T; Shinohe, T; Stanislawski, T | 1 |
Albaret, C; Bartels, CF; Fortier, PL; Froment, MT; Lockridge, O; Masson, P | 1 |
Arreaza, G; Deutsch, DG; Omeir, RL | 1 |
Adamo, G; Camardella, L; Carratore, V; Febbraio, F; Manco, G; Rossi, M | 1 |
Atkins, J; Glynn, P | 1 |
Casida, JE; Haux, JE; Quistad, GB | 1 |
Casida, JE; Quistad, GB; Sparks, SE; Zhang, N | 1 |
Dahlgren, C; Karlsson, A | 1 |
Beti, R; Cattaneo, A; Gabriel, JM; Ojha, M | 1 |
Elhammer, AP; Kézdy, FJ; Kurosaka, A; Tenno, M; Toba, S | 1 |
Masuda, T; Ohta, H; Shimada, H; Suzuki, T; Takamiya, K; Tsuchiya, T; Yamada, T | 1 |
Matoney, L; Xie, M; Yan, B; Yang, D | 1 |
MAY, SC; SCHAFFER, NK; SUMMERSON, WH | 2 |
GREENBERG, H; NACHMANSOHN, D | 1 |
AGREN, G; ENGSTROM, L | 1 |
HOKIN, LE; YODA, A | 1 |
D'Souza, CA; Moscarello, MA; She, YM; Wood, DD | 1 |
Abraham, CR; Bagchi, S; Hildebrant, R; Scaloni, A; Widom, RL; Yamin, R | 1 |
Froment, MT; Li, H; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM | 1 |
Asojo, O; Carlson, JE; Carr, J; Ding, SJ; Hinrichs, SH; Li, B; Li, Y; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM; Thompson, CM; Tong, L; Xue, W | 1 |
Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
2 review(s) available for isoflurophate and serine
Article | Year |
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Chemistry of the hemostatic mechanism and its relationship to the action of heparin.
Topics: Alpha-Globulins; alpha-Macroglobulins; Antithrombin III; Antithrombins; Arginine; Binding Sites; Factor IX; Factor XI; Factor XII; Fibrinolysin; Fibrinolysis; Hemostasis; Heparin; Humans; Isoflurophate; Kallikreins; Kinetics; Lysine; Macrophages; Protease Inhibitors; Serine; Structure-Activity Relationship; Thrombin | 1977 |
Reaction mechanisms in the release of mediators of immediate hypersensitivity from human lung tissue.
Topics: Anaphylaxis; Animals; Calcium; Chemotaxis; Chromatography, Gel; Chromatography, Paper; Complement System Proteins; Cyclic AMP; Cyclic GMP; Eosinophils; Esterases; Guinea Pigs; Histamine; Histamine Release; Humans; Hypersensitivity, Immediate; Immunization; Immunoglobulin E; Isoflurophate; Leukocytes; Lung; Lung Compliance; Mast Cells; Peptides; Rats; Serine; Skin; SRS-A | 1974 |
111 other study(ies) available for isoflurophate and serine
Article | Year |
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(Diisopropylphosphoryl)serine proteinases. Proton and phosphorus-31 nuclear magnetic resonance-pH titration studies.
Topics: Animals; Binding Sites; Cattle; Chymotrypsinogen; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Serine; Swine; Trypsin; Trypsinogen | 1979 |
Plasminogen and plasmin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Enzyme Activation; Fibrinolysin; Histidine; Humans; Isoenzymes; Isoflurophate; Macromolecular Substances; Methods; Plasminogen; Rabbits; Serine; Terminology as Topic; Thromboplastin; Tosyllysine Chloromethyl Ketone | 1976 |
Production of a serine-protease with macrophage migration-inhibitory factor activity by virus-transformed cells and human tumor cell lines.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Migration Inhibition; Cell Transformation, Neoplastic; Cell-Free System; Chymotrypsin; Cricetinae; Endopeptidases; HeLa Cells; Hot Temperature; Humans; Isoflurophate; Lymphocytes; Macrophage Migration-Inhibitory Factors; Macrophages; Mice; Mice, Inbred BALB C; Neoplasms; Polyomavirus; Serine; Simian virus 40; Trypsin Inhibitors | 1975 |
Structural studies of staphylococcal protease. III. Binding of anions to the spin-labeled enzyme.
Topics: Binding Sites; Electron Spin Resonance Spectroscopy; Endopeptidases; Isoflurophate; Protein Conformation; Serine; Spin Labels; Staphylococcus aureus | 1978 |
Hydrolysis of plant cuticle by plant pathogens. Properties of cutinase I, cutinase II, and a nonspecific esterase isolated from Fusarium solani pisi.
Topics: Binding Sites; Carboxylic Ester Hydrolases; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Fusarium; Hydrogen-Ion Concentration; Hydrolases; Hydrolysis; Hydroxy Acids; Isoenzymes; Isoflurophate; Kinetics; Lipid Metabolism; Paraoxon; Plants; Polymers; Serine; Structure-Activity Relationship; Sulfhydryl Reagents | 1975 |
Human leukocyte migration inhibitory factor (LIF). I. Effect of synthetic and naturally occurring esterase and protease inhibitors.
Topics: Aprotinin; Dose-Response Relationship, Drug; Esterases; Fluorides; Humans; Isoflurophate; Lymphocytes; Macrophage Migration-Inhibitory Factors; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Time Factors; Trypsin Inhibitors | 1977 |
Human leukocyte migration inhibitory factor (LIF). II. Partial biochemical characterization of the substrate specificities for this lymphokine.
Topics: Benzyl Compounds; Binding, Competitive; Carboxylic Acids; Cell Migration Inhibition; Drug Interactions; Esterases; Esters; Humans; Indicators and Reagents; Isoflurophate; Leukocytes; Lymphocytes; Macrophage Migration-Inhibitory Factors; Molecular Weight; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine | 1977 |
Serine enzymes released by cultured neoplastic cells.
Topics: Binding Sites; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Esterases; Humans; Isoflurophate; Kinetics; Neoplasms; Peptide Hydrolases; Plasminogen Activators; Serine; Trypsin Inhibitors | 1978 |
Activation of bovine factor X (Stuart factor)--analogy with pancreatic zymogen-enzyme systems.
Topics: Animals; Binding Sites; Cattle; Circular Dichroism; Enzyme Activation; Enzyme Precursors; Esterases; Factor X; Isoflurophate; Kinetics; Pancreas; Peptide Hydrolases; Protein Binding; Serine; Sulfones | 1978 |
DFP-sensitive polypeptides of the guinea pig peritoneal macrophage.
Topics: Alkylation; Animals; Ascitic Fluid; Binding Sites; Esterases; Guinea Pigs; Isoflurophate; Macrophages; Molecular Weight; Peptides; Serine | 1978 |
Evidence that neutral protease from calf thymus chromatin is a serine type enzyme.
Topics: Animals; Cattle; Chromatin; Chromatography, Ion Exchange; Guanidines; Histones; Isoflurophate; Methods; Peptide Hydrolases; Protease Inhibitors; Serine; Thymus Gland; Trypsin Inhibitors | 1975 |
Evidence for an "active serine" in each fatty acid synthetase peptide.
Topics: Animals; Binding Sites; Fatty Acid Synthases; Geese; Isoflurophate; Malonates; Molecular Weight; Protein Binding; Sebaceous Glands; Serine | 1976 |
Evidence that the methylesterase of bacterial chemotaxis may be a serine hydrolase.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Carboxylic Ester Hydrolases; Chemotactic Factors; Chemotaxis; Escherichia coli; Isoflurophate; Molecular Sequence Data; Serine; Serine Endopeptidases | 1992 |
Structural determination of the essential serine and glycosylation sites of carboxypeptidase P.
Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Carboxypeptidases; Glycosylation; Isoflurophate; Mass Spectrometry; Molecular Sequence Data; Multigene Family; Peptide Fragments; Peptide Mapping; Protein Denaturation; Sequence Homology, Nucleic Acid; Serine; Serine Endopeptidases; Serine Proteinase Inhibitors | 1992 |
The esterolytic activity of epidermolytic toxins.
Topics: Animals; Enzyme Stability; Esterases; Exfoliatins; Glutamates; Hot Temperature; Hydrolysis; Isoflurophate; Kinetics; Metalloendopeptidases; Mice; Serine; Serine Endopeptidases | 1992 |
Structure-function relationships in human lecithin:cholesterol acyltransferase. Site-directed mutagenesis at serine residues 181 and 216.
Topics: Amino Acid Sequence; Animals; Base Sequence; Catalysis; Cell Line; Cricetinae; Cricetulus; Female; Humans; Isoflurophate; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Ovary; Phosphatidylcholine-Sterol O-Acyltransferase; Serine; Structure-Activity Relationship | 1991 |
The reactive serine residue of epidermolytic toxin A.
Topics: Amino Acid Sequence; Bacterial Toxins; Binding Sites; Chromatography, High Pressure Liquid; Exfoliatins; Isoflurophate; Molecular Sequence Data; Peptide Fragments; Sequence Homology, Nucleic Acid; Serine; Serine Endopeptidases; Staphylococcus aureus; Trypsin | 1990 |
Human milk bile-salt stimulated lipase: further investigations on the amino-acids residues involved in the catalytic site.
Topics: Acylation; Adsorption; Bile Acids and Salts; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chemistry, Physical; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen Bonding; Isoflurophate; Isoxazoles; Kinetics; Lipase; Micelles; Milk, Human; Phosphorylation; Serine; Spectrophotometry; Structure-Activity Relationship | 1989 |
Influenza C virus esterase: analysis of catalytic site, inhibition, and possible function.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chick Embryo; Coumarins; Erythrocytes; Esterases; Gammainfluenzavirus; Isoflurophate; Kinetics; Molecular Sequence Data; Orthomyxoviridae; Receptors, Virus; Serine; Structure-Activity Relationship; Viral Plaque Assay | 1989 |
O-acetylation and de-O-acetylation of sialic acids. Sialic acid esterases of diverse evolutionary origins have serine active sites and essential arginine residues.
Topics: Acetylation; Acetylesterase; Amino Acid Sequence; Animals; Arginine; Binding Sites; Biological Evolution; Carboxylic Ester Hydrolases; Dictyostelium; Humans; Isoflurophate; Molecular Sequence Data; Plants; Sequence Homology, Nucleic Acid; Serine; Sialic Acids; Species Specificity | 1989 |
Determination of the active-site serine of 6-aminohexanoate-dimer hydrolase.
Topics: Affinity Labels; Amidohydrolases; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Flavobacterium; Isoflurophate; Molecular Sequence Data; Peptide Fragments; Protein Engineering; Serine; Trypsin | 1989 |
Study of the peptidasic site of cholinesterase: preliminary results.
Topics: Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Diethyl Pyrocarbonate; Histidine; Humans; Isoflurophate; Neuraminidase; Organophosphorus Compounds; Peptide Hydrolases; Quinolines; Serine; Soman; Substance P; Tosyllysine Chloromethyl Ketone | 1985 |
Kinetic investigations into the interactions of aprophen with cholinesterases and a carboxylesterase.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Humans; Isoflurophate; Kinetics; Phenylpropionates; Physostigmine; Pralidoxime Compounds; Serine | 1986 |
Amino acid sequence of the serine active-site region of the medium-chain S-acyl fatty acid synthetase thioester hydrolase from rat mammary gland.
Topics: Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Binding Sites; DNA; Esterases; Fatty Acid Synthases; Female; Isoflurophate; Mammary Glands, Animal; Rats; Serine; Thiolester Hydrolases | 1987 |
Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus.
Topics: Acetylesterase; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gammainfluenzavirus; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Isoflurophate; Molecular Sequence Data; Orthomyxoviridae; Serine; Viral Envelope Proteins; Virus Cultivation | 1988 |
Proteinase K from Tritirachium album limber. I. Molecular mass and sequence around the active site serine residue.
Topics: Amino Acid Sequence; Binding Sites; Cyanogen Bromide; Endopeptidase K; Endopeptidases; Isoflurophate; Mitosporic Fungi; Molecular Weight; Peptide Fragments; Protein Binding; Serine; Subtilisins | 1985 |
Multiple active forms of thrombin. 3. Polypeptide chain location of active site serine and carbohydrate.
Topics: Animals; Anthracenes; Binding Sites; Carbohydrates; Cattle; Chromatography, Gel; Electrophoresis, Disc; Fluoresceins; Guanidines; Isoflurophate; Macromolecular Substances; Mathematics; Molecular Weight; Quaternary Ammonium Compounds; Serine; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Staining and Labeling; Thrombin; Tritium | 1973 |
DFP as a prerequisite in the histochemical demonstration of choline acetyltransferase.
Topics: Acetates; Acetyl Coenzyme A; Acetylcholine; Acetyltransferases; Animals; Carbon Isotopes; Choline; Cholinesterase Inhibitors; Histocytochemistry; Isoflurophate; Rats; Serine; Spinal Cord; Staining and Labeling | 1973 |
Studies of the heterogeneity of Streptomyces griseus protease. Isolation and characterization of an alkaline serine protease from commercial pronase-P derived from Streptomyces griseus K1.
Topics: Amino Acids; Calcium; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Polyacrylamide Gel; Freeze Drying; Hydrogen-Ion Concentration; Isoflurophate; Molecular Weight; Pancreatic Elastase; Peptide Hydrolases; Phosphorus Radioisotopes; Pronase; Protease Inhibitors; Serine; Streptomyces griseus; Temperature; Time Factors; Urea | 1973 |
Studies on the active center of human plasmin. The serine and histidine residues.
Topics: Amino Acids; Autoanalysis; Autoradiography; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Electrophoresis; Fibrinolysin; Fibrinolytic Agents; Histidine; Humans; Isoflurophate; Ketones; Kinetics; Methods; Methylation; Oxidation-Reduction; Peptides; Phosphorus Isotopes; Plasminogen; Protein Hydrolysates; Serine; Trypsin | 1969 |
Studies on the active center of human plasmin. Partial amino acid sequence of a peptide containing the active center serine residue.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Endopeptidases; Fibrinolysin; Humans; Isoflurophate; Methods; Peptides; Phosphorus Isotopes; Serine; Trypsin | 1969 |
Effect of irreversible inhibitors on transport ATPase.
Topics: Adenosine Triphosphatases; Alkanes; Animals; Binding Sites; Biological Transport; Brain; Carbon Isotopes; Enzyme Activation; Isoflurophate; Microsomes; Nitrophenols; Phosphates; Phosphorus Isotopes; Potassium; Serine; Sodium; Sulfonic Acids; Swine | 1969 |
Bovine factor X 1a (activated Stuart factor). Evidence of homology with mammalian serine proteases.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Biological Evolution; Cattle; Chromatography, Gel; Chymotrypsin; Cyanogen Bromide; Endopeptidases; Enzyme Activation; Factor X; Fibrinolysin; Humans; Isoflurophate; Macromolecular Substances; Pancreas; Peptides; Phosphoric Acids; Phosphorus Isotopes; Serine; Species Specificity; Thrombin; Trypsin | 1972 |
Mechanism of action of alpha-1-antitrypsin.
Topics: alpha 1-Antitrypsin; Amino Acids; Anilides; Arginine; Aspartic Acid; Benzoates; Binding Sites; Binding, Competitive; Cholinesterase Inhibitors; Chymotrypsin; Fibrinolysin; Glyoxal; Histidine; Isoflurophate; Leucine; Lysine; Nitro Compounds; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Serine; Structure-Activity Relationship; Subtilisins; Thrombin; Trypsin Inhibitors | 1973 |
Organophosphate spin-label studies of inhibited esterases, alpha-chymotrypsin and cholinesterase.
Topics: Binding Sites; Cholinesterase Inhibitors; Cholinesterases; Chymotrypsin; Electron Spin Resonance Spectroscopy; Isoflurophate; Phosphates; Serine; Thrombin; Trypsin | 1969 |
Physiochemical properties of thermomycolase, the thermostable, extracellular, serine protease of the fungus Malbranchea pulchella.
Topics: Actinomyces; Binding Sites; Calcium; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deuterium; Drug Stability; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Hot Temperature; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Macromolecular Substances; Molecular Weight; Protein Binding; Protein Conformation; Protein Denaturation; Serine; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation; Viscosity | 1974 |
Partial purification and characterization of a chymotrypsin-like enzyme from human neutrophil leucocytes.
Topics: Binding Sites; Chromatography, Gel; Chymotrypsin; Dithioerythritol; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Molecular Weight; Neutrophils; Organ Specificity; Oxidation-Reduction; Pancreas; Phenylalanine; Phosphorus Radioisotopes; Protein Binding; Serine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tosyl Compounds; Ultracentrifugation | 1974 |
Comparative study of various serine alkaline proteinases from microorganisms. Esterase activity against N-acylated peptide ester substrates.
Topics: Aspergillus; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Crystallization; Esterases; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Serine; Species Specificity; Streptomyces; Structure-Activity Relationship; Subtilisins; Time Factors | 1974 |
Self purification of two serine endopeptidases.
Topics: Catalysis; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Electrophoresis, Disc; Endopeptidases; Ethanol; Guanidines; Isoflurophate; Isoleucine; Peptide Hydrolases; Phosphorus Isotopes; Pronase; Protein Conformation; Serine; Tyrosine | 1972 |
Effects of protease inhibitors on protein breakdown in Escherichia coli.
Topics: Amidines; Aminobutyrates; Bacterial Proteins; Benzyl Compounds; Canavanine; Chlorine; Culture Media; Enzyme Induction; Escherichia coli; Fluorine; Galactosidases; Hydro-Lyases; Isoflurophate; Leucine; Protease Inhibitors; Serine; Sulfonic Acids; Toluene; Tosyl Compounds; Tritium; Trypsin Inhibitors; Tryptophan | 1972 |
Radiochemical determination of a unique sequence around the reactive serine residue of a di-isopropyl phosphorofluoridate-sensitive plant carboxypeptidase and a yeast peptidase.
Topics: Amino Acid Sequence; Carboxypeptidases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Fluorine; Hydrolysis; Isoflurophate; Peptide Hydrolases; Phosphorus Isotopes; Plants; Saccharomyces cerevisiae; Serine | 1972 |
Serine at the active center of yeast carboxypeptidase.
Topics: Acetamides; Amino Acid Sequence; Amino Acids; Binding Sites; Carboxypeptidases; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Endopeptidases; Hot Temperature; Hydroxymercuribenzoates; Iodoacetates; Isoflurophate; Pepsin A; Phosphopeptides; Phosphoproteins; Phosphorus Radioisotopes; Protein Denaturation; Saccharomyces cerevisiae; Serine; Thiocyanates; Urea | 1973 |
Inability to block the activity of guinea pig migration inhibitory factor with di-isopropyl phosphorofluoridate.
Topics: Animals; Ascitic Fluid; Cell Migration Inhibition; Cells, Cultured; Concanavalin A; Esterases; Guinea Pigs; Isoflurophate; Lymphocytes; Macrophage Migration-Inhibitory Factors; Macrophages; Serine | 1974 |
The proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). I. Purification of four serine endopeptidases.
Topics: Amines; Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Disc; Endopeptidases; Esterases; Hydrogen-Ion Concentration; Hydrolysis; Isoflurophate; Molecular Weight; Peptide Hydrolases; Peptides; Phosphorus Isotopes; Pronase; Protease Inhibitors; Serine; Streptomyces; Streptomyces griseus; Structure-Activity Relationship; Trypsin | 1972 |
An alkaline protease from Acremonium kiliense. Specificity, kinetics, and effect of pH.
Topics: Arginine; Benzoates; Benzyl Compounds; Caseins; Dipeptides; Esters; Fluorine; Glutarates; Hydrogen-Ion Concentration; Imidazoles; Insulin; Iodoacetates; Isoflurophate; Kinetics; Mercaptoethanol; Mitosporic Fungi; Nitro Compounds; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Serine; Structure-Activity Relationship; Sulfonic Acids | 1972 |
Bovine factor X 1 (Stuart factor). Mechanism of activation by protein from Russell's viper venom.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbohydrates; Cattle; Chromatography, Gel; Electrophoresis, Disc; Endopeptidases; Enzyme Activation; Enzyme Precursors; Factor X; Fluorine; Glycopeptides; Isoflurophate; Molecular Weight; Peptides; Phosphoric Acids; Phosphorus Isotopes; Proteins; Serine; Snakes; Sulfonic Acids; Tosyl Compounds; Venoms | 1972 |
Amino acid sequence in the vicinity of the reactive serine residue in shrimp trypsin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Carbon Isotopes; Chromatography, DEAE-Cellulose; Decapoda; Isoflurophate; Peptides; Serine; Species Specificity; Trypsin | 1973 |
The activation of prothrombin. II. Partial reactions, physical and chemical characterization of the intermediates of activation.
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Citrates; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Factor X; Isoflurophate; Molecular Weight; Oxidation-Reduction; Prothrombin; Serine; Sodium Dodecyl Sulfate; Spectrophotometry; Thrombin; Tritium; Trypsin; Ultracentrifugation | 1973 |
Depolymerization of a hydroxy fatty acid biopolymer, cutin, by an extracellular enzyme from Fusarium solani f. pisi: isolation and some properties of the enzyme.
Topics: Amides; Carbon Radioisotopes; Chloromercuribenzoates; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Fusarium; Hydrogen-Ion Concentration; Hydrolases; Iodoacetates; Isoflurophate; Kinetics; Lipid Metabolism; Plants; Polymers; Serine; Spectrophotometry; Time Factors | 1973 |
Secretion of plasminogen activator by stimulated macrophages.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Fibrinolysis; Isoflurophate; Macrophages; Mice; Molecular Weight; Muramidase; Peptide Hydrolases; Plasminogen; Serine; Thioglycolates; Tritium | 1974 |
Identification of serine and histidine as essential amino-acid residues in the coagulant enzyme ancrod.
Topics: Amines; Arginine; Benzamides; Binding Sites; Chlorine; Esters; Ethanol; Hemostatics; Histidine; Hydrolysis; Isoflurophate; Ketones; Kinetics; Molecular Weight; Nitrobenzenes; Peptide Hydrolases; Phosphorus Radioisotopes; Protease Inhibitors; Serine; Venoms | 1974 |
Isolation and partial characterization of the larval midgut trypsin from the tobacco hornworm, Manduca sexta, Johannson (Lepidoptera: Sphingidae).
Topics: Amino Acids; Animals; Binding Sites; Chloromercuribenzoates; Chromatography, Affinity; Digestive System; Electrophoresis, Polyacrylamide Gel; Fluorides; Glucagon; Histidine; Hydrogen-Ion Concentration; Insecta; Isoflurophate; Kinetics; Larva; Molecular Weight; Peptide Hydrolases; Protein Binding; Protein Conformation; Serine; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfonic Acids; Trypsin | 1974 |
Fibrinolytic activity associated with human neuroblastoma cells.
Topics: Blood; Cell Line; Cells, Cultured; Culture Media; Fibrinolysis; Fibroblasts; Humans; In Vitro Techniques; Isoflurophate; Neuroblastoma; Peptide Hydrolases; Plasminogen; Serine; Skin | 1974 |
Serine-containing active center of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Aspergillus; Bacillus subtilis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Isoflurophate; Methionine; Peptide Hydrolases; Phosphorus Isotopes; Serine; Streptomyces; Threonine; Trypsin | 1969 |
[Characterization of 2 endopeptidases excreted by B. subtilis Marburg during sporulation].
Topics: Bacillus subtilis; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Edetic Acid; Esterases; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Metals; Mutation; Peptide Hydrolases; Phenanthrolines; Protease Inhibitors; Serine; Spores | 1969 |
[Organophosphate inhibitors as tools for the enzymologist].
Topics: Acetanilides; Aminohydrolases; Animals; Binding Sites; Esterases; Immunodiffusion; Isoflurophate; Kidney; Methemoglobin; Microsomes, Liver; Nitrophenols; Phosphoric Acids; Phosphorus Isotopes; Procaine; Serine; Swine | 1970 |
Human pancreatic enzymes. Isolation and properties of a major form of chymotrypsin.
Topics: Acetone; Amino Acids; Animals; Asparagine; Butanones; Calcium Chloride; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis, Disc; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Quaternary Ammonium Compounds; Rabbits; Serine; Species Specificity; Spectrophotometry; Sulfates; Trypsin; Ultracentrifugation; Ultraviolet Rays | 1971 |
Marine bacterial proteases. I. Characterization of an endopeptidase produced by Vibrio B-30.
Topics: Acetamides; Ammonium Sulfate; Ascorbic Acid; Calcium Chloride; Chemical Precipitation; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cobalt; Copper; Crystallization; Cyanides; Cysteine; Cystine; Drug Stability; Edetic Acid; Electrophoresis; Endopeptidases; Enzyme Activation; Glutathione; Hydrogen-Ion Concentration; Iodoacetates; Isoflurophate; Kinetics; Magnesium; Manganese; Molecular Weight; Nickel; Potassium; Protease Inhibitors; Protein Denaturation; Serine; Temperature; Thioglycolates; Vibrio; Zinc | 1971 |
Action of organophosphates and sulfonyl halides on porcine pancreatic lipase.
Topics: Amino Acid Sequence; Amino Acids; Animals; Bile Acids and Salts; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Histidine; Iodoacetates; Isoflurophate; Lipase; Nitrophenols; Pancreas; Peptides; Phosphoric Acids; Phosphorus Isotopes; Serine; Structure-Activity Relationship; Sulfonic Acids; Sulfur Isotopes; Tyrosine | 1972 |
Conformational and activity changes on subtilisin cleavage of carboxypeptidase A.
Topics: Aspartic Acid; Bacillus; Bacteria; Benzyl Compounds; Binding Sites; Carboxypeptidases; Catalysis; Circular Dichroism; Endopeptidases; Formates; Glycine; Hippurates; Hydrolysis; Isoflurophate; Kinetics; Lactates; Nitrobenzenes; Pancreatic Elastase; Phenylalanine; Pronase; Propionates; Protein Conformation; Serine | 1971 |
The kinin system of human plasma. V. The probable derivation of prekallikrein activator from activated Hageman factor (XIIa).
Topics: Adult; Arginine; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Esterases; Factor XII; Humans; Isoelectric Focusing; Isoflurophate; Kaolin; Kinins; Middle Aged; Serine; Thromboplastin; Trypsin | 1971 |
Some catalytic properties of IRC-50 Arvin.
Topics: Animals; Anticoagulants; Arginine; Binding Sites; Blood Coagulation; Chromatography, Ion Exchange; Esterases; Esters; Fibrinogen; Fluorides; Isoflurophate; Serine; Snakes; Sulfonic Acids; Venoms | 1971 |
Non-pancreatic proteases of the chymotrypsin family. I. A chymotrypsin-like protease from rat mast cells.
Topics: Acrylates; Animals; Arginine; Benzoates; Binding Sites; Cell Count; Cell Fractionation; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Dextrans; Endopeptidases; Enzyme Precursors; Esters; Gels; Histidine; Hydrogen-Ion Concentration; Isoflurophate; Ketones; Kinetics; Male; Mast Cells; Methods; Microscopy, Electron; Molecular Weight; Osmolar Concentration; Peritoneal Cavity; Phosphorus Isotopes; Potassium Chloride; Rats; Serine; Sulfonic Acids; Toluene; Tritium; Tyrosine | 1971 |
The modification of essential carboxylic acid side chains of trypsin.
Topics: Amidines; Amines; Aspartic Acid; Benzoates; Binding Sites; Boric Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Enzyme Activation; Ethylamines; Fluorine; Glutamates; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Isoflurophate; Ketones; Oxazoles; Serine; Sulfonic Acids; Trypsin; Trypsin Inhibitors | 1969 |
The inhibition of porcine pancreas kallikrein by di-isopropyl-fluorophosphate. Kinetics, stoichiometry, and nature of the group phosphorylated.
Topics: Animals; Buffers; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Drug Stability; Hydrogen-Ion Concentration; Hydrolases; Isoflurophate; Kallikreins; Kinetics; Methods; Pancreas; Phosphorus; Phosphorus Isotopes; Serine; Spectrophotometry; Swine; Thioglycolates; Tromethamine; Trypsin | 1969 |
Isolation and partial characterization of highly purified protocollagen proline hydroxylase.
Topics: Alcohols; Amino Acids; Animals; Aspartic Acid; Benzoates; Chick Embryo; Chromatography, Gel; Collagen; Electrophoresis, Disc; Ethylmaleimide; Glutamates; Glycine; Isoflurophate; Lysine; Mercury; Methods; Mixed Function Oxygenases; Molecular Weight; Proline; Serine; Sulfur; Ultracentrifugation | 1970 |
Interactions of the endopeptidase subunit of bovine procarboxypeptidase A-S6.
Topics: Amino Acids; Animals; Binding Sites; Butanones; Carbon Isotopes; Carboxypeptidases; Cattle; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cinnamates; Electrophoresis, Disc; Endopeptidases; Enzyme Activation; Enzyme Precursors; Formates; Histidine; Imidazoles; Isoflurophate; Molecular Weight; Pancreas; Peptides; Phosphorus Isotopes; Serine; Trypsin | 1970 |
The transient inactivation of trypsin by mild acetylation with N-acetylimidazole.
Topics: Acetates; Animals; Binding Sites; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Histidine; Hydrogen-Ion Concentration; Imidazoles; Isoflurophate; Lysine; Models, Chemical; Phosphorus Isotopes; Serine; Solvents; Spectrophotometry; Trypsin; Tyrosine | 1970 |
Yeast aldehyde dehydrogenase. 3. Preparation of three homogeneous species.
Topics: Aldehydes; Amino Acids; Chemical Phenomena; Chemistry; Electrophoresis, Disc; Esterases; Fluorides; Gels; Guanidines; Isoflurophate; Methods; Oxidoreductases; Potassium Chloride; Saccharomyces; Serine; Ultracentrifugation | 1970 |
The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Butanones; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cystine; Electrophoresis; Esterases; Histidine; Insulin; Isoflurophate; Methionine; Methylcellulose; Peptide Hydrolases; Peptides; Serine; Streptomyces; Sulfides; Sulfonic Acids; Toluene; Tyrosine | 1971 |
Studies on Streptomyces griseus protease. II. The amino acid sequence around the reactive serine residue of DFP-sensitive components with esterase activity.
Topics: Amino Acid Sequence; Amino Acids; Autoanalysis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Esterases; Isoflurophate; Paper; Peptide Hydrolases; Phosphorus; Phosphorus Isotopes; Protein Hydrolysates; Serine; Streptomyces | 1968 |
The primary structure at the DFP-reacting site of a proteolytic enzyme from a strain of arthrobacter.
Topics: Amino Acid Sequence; Amino Acids; Arthrobacter; Binding Sites; Chromatography, Ion Exchange; Electrophoresis; Isoflurophate; Paper; Peptide Hydrolases; Peptides; Phosphorus; Phosphorus Isotopes; Serine | 1968 |
Purification and properties of an anionic zymogen of phospholipase A from porcine pancreas.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Autolysis; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Peptide Hydrolases; Peptides; Phospholipases; Serine; Swine; Trypsin | 1968 |
Isolation and characterization of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acids; Aspergillus; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Glycine; Isoflurophate; Molecular Weight; Peptide Hydrolases; Phosphorus Isotopes; Serine; Ultracentrifugation | 1969 |
The inhibition of activated Factor X with di: isopropyl fluorophosphate.
Topics: Amino Acids; Animals; Aspartic Acid; Cattle; Chromatography, Thin Layer; Electrophoresis; Esterases; Factor X; Glycine; Isoflurophate; Peptides; Phosphorus Isotopes; Serine | 1969 |
Reaction of an extracellular proteolytic enzyme from a strain of Arthrobacter with diisopropylphosphofluoridate (DFP).
Topics: Amino Acid Sequence; Arthrobacter; Chymotrypsin; Fluorine; Isoflurophate; Peptide Hydrolases; Radioisotopes; Serine | 1966 |
The metabolism of triglycerides by spores of Penicillium roqueforti.
Topics: Alanine; Azides; Chloramphenicol; Dinitrophenols; Enzymes; Esterases; Glycerides; Isoflurophate; Ketones; Oxygen Consumption; Penicillium; Phosphates; Proline; Serine; Spores; Triglycerides | 1967 |
Concerning the nature of the alpha- and beta-lytic proteases of Sorangium sp.
Topics: Amino Acid Sequence; Arthrobacter; Autoradiography; Bacteria; Bacteriolysis; Chemical Phenomena; Chemistry; Chymotrypsin; Dialysis; Endopeptidases; Enzymes; Filtration; Isoflurophate; Peptide Hydrolases; Phosphorus Isotopes; Serine; Trypsin | 1967 |
A unique amino acid sequence around a reactive serine residue in peptidases from French beans and yeast.
Topics: Amino Acid Sequence; Enzymes; Isoflurophate; Peptide Hydrolases; Phosphorus Isotopes; Plants, Edible; Saccharomyces; Serine | 1967 |
Reactive serine in human adenovirus hexon polypeptide.
Topics: Adenoviruses, Human; Cell Line; Esterases; HeLa Cells; Humans; Isoflurophate; Peptide Hydrolases; Peptides; Serine; Viral Proteins | 1980 |
The requirement for esterase activation in T cell replacing factor (TRF)-induced IgG production in a human B blastoid cell line.
Topics: Adenosine Monophosphate; B-Lymphocytes; Cell Division; Cell Line; Esterases; Humans; Immunoglobulin G; Interleukin-5; Isoflurophate; Lymphokines; Phenylmethylsulfonyl Fluoride; Serine; Tosylarginine Methyl Ester | 1982 |
Primary structure of a chymotryptic peptide containing the "active serine" of the thioesterase domain of fatty acid synthase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Chymotrypsin; Fatty Acid Synthases; Geese; Humans; Isoflurophate; Peptide Fragments; Serine; Species Specificity; Thiolester Hydrolases | 1981 |
Is the seryl residue essential for catalytic activity of rat liver arginase?
Topics: Animals; Arginase; Binding Sites; Isoflurophate; Kinetics; Liver; Phenylmethylsulfonyl Fluoride; Protein Binding; Rats; Serine; Sulfones | 1982 |
Analysis of the proteolytic activity of a recombinant form of apolipoprotein(a).
Topics: Amino Acid Sequence; Apolipoproteins; Apoprotein(a); Arginine; Base Sequence; Cell Line; Fibrinolysin; Humans; Hydrolysis; Isoflurophate; Kringles; Lipoprotein(a); Molecular Sequence Data; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tissue Plasminogen Activator; Tritium | 1995 |
Identification of active site residues of the Tsp protease.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Endopeptidases; Isoflurophate; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protease Inhibitors; Sequence Homology, Amino Acid; Serine; Substrate Specificity | 1995 |
The catalytic triad of the influenza C virus glycoprotein HEF esterase: characterization by site-directed mutagenesis and functional analysis.
Topics: Acetylesterase; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Cell Line; Dogs; Enzyme Inhibitors; Gammainfluenzavirus; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Histidine; Isoflurophate; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Recombinant Fusion Proteins; Serine; Serine Endopeptidases; Sialic Acids; Viral Fusion Proteins; Viral Proteins | 1995 |
Identification of the serine residue at the active site of the herpes simplex virus type 1 protease.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Binding Sites; Cells, Cultured; Chromatography, High Pressure Liquid; Endopeptidases; Isoflurophate; Kinetics; Mass Spectrometry; Molecular Sequence Data; Moths; Peptide Fragments; Peptide Mapping; Protease Inhibitors; Serine; Serine Endopeptidases; Simplexvirus; Viral Proteins | 1994 |
Effects of the residue adjacent to the reactive serine on the substrate interactions of Drosophila esterase 6.
Topics: Acetylthiocholine; Amino Acids; Animals; Binding Sites; Carboxylesterase; Carboxylic Ester Hydrolases; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Point Mutation; Serine; Substrate Specificity; Temperature; Transformation, Genetic | 1993 |
Identification of an essential serine residue in glucagon: implication for an active site triad.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Glucagon; In Vitro Techniques; Isoflurophate; Liver; Male; Molecular Structure; Phenylmethylsulfonyl Fluoride; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship | 1994 |
Determination of the active sites serine of the poly (3-hydroxybutyrate) depolymerases of Pseudomonas lemoignei (PhaZ5) and of Alcaligenes faecalis.
Topics: Alcaligenes; Amino Acid Sequence; Base Sequence; Binding Sites; Carboxylic Ester Hydrolases; Enzyme Inhibitors; Escherichia coli; Isoflurophate; Molecular Sequence Data; Molecular Weight; Mutation; Pseudomonas; Recombinant Fusion Proteins; Sequence Alignment; Serine | 1996 |
Aging of di-isopropyl-phosphorylated human butyrylcholinesterase.
Topics: Aging; Animals; Binding Sites; Butyrylcholinesterase; CHO Cells; Cholinesterase Inhibitors; Cricetinae; Humans; Isoflurophate; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Recombinant Proteins; Serine; Time Factors; Transfection | 1997 |
Identification of two serine residues involved in catalysis by fatty acid amide hydrolase.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Catalysis; COS Cells; Cysteine; Isoflurophate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phospholipases A; Protease Inhibitors; Serine; Sulfhydryl Compounds | 1999 |
Homology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus.
Topics: Affinity Labels; Amino Acid Sequence; Archaeoglobus fulgidus; Binding Sites; Carboxylic Ester Hydrolases; Computer Graphics; Enzyme Stability; Hot Temperature; Isoflurophate; Lipase; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sequence Alignment; Serine; Thermodynamics | 2000 |
Membrane association of and critical residues in the catalytic domain of human neuropathy target esterase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalytic Domain; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Humans; Isoflurophate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 2000 |
Phosphobutyrylcholinesterase: phosphorylation of the esteratic site of butyrylcholinesterase by ethephon [(2-chloroethyl)phosphonic acid] dianion.
Topics: Animals; Binding Sites; Binding, Competitive; Butyrylcholinesterase; Butyrylthiocholine; Chickens; Cholinesterase Inhibitors; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Horses; Humans; Hydrogen-Ion Concentration; Hydrolysis; Isoflurophate; Kinetics; Mice; Phosphorylation; Rabbits; Rats; Serine; Species Specificity; Swine; Time Factors; Tritium | 2000 |
Phosphoacetylcholinesterase: toxicity of phosphorus oxychloride to mammals and insects that can be attributed to selective phosphorylation of acetylcholinesterase by phosphorodichloridic acid.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Binding Sites; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Female; Houseflies; Hydrolysis; Isoflurophate; Kinetics; Male; Mice; Organophosphorus Compounds; Phosphorus Compounds; Phosphorylation; Physostigmine; Serine; Tritium | 2000 |
Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate.
Topics: Cell-Free System; Humans; Hydrogen Peroxide; Ionomycin; Ionophores; Isoflurophate; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxygen; Phagocytosis; Reactive Oxygen Species; Serine; Serine Proteinase Inhibitors; Subcellular Fractions; Superoxides; Time Factors | 2002 |
A novel N(alpha)-acetyl alanine aminopeptidase from Allomyces arbuscula.
Topics: Acetylation; Binding Sites; CD13 Antigens; Chelating Agents; Chromatography, Gel; Chytridiomycota; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Molecular Weight; Serine; Serine Proteinase Inhibitors; Subcellular Fractions; Substrate Specificity; Temperature; Zinc | 2002 |
Identification of two cysteine residues involved in the binding of UDP-GalNAc to UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1).
Topics: 4-Chloromercuribenzenesulfonate; Animals; Binding Sites; Cattle; COS Cells; Cysteine; DNA Primers; Enzyme Activation; Gene Deletion; Glycosylation; Humans; Isoflurophate; Kinetics; Mutagenesis, Site-Directed; N-Acetylgalactosaminyltransferases; Polymerase Chain Reaction; Polypeptide N-acetylgalactosaminyltransferase; Rats; Recombinant Proteins; Serine; Transfection; Uridine Diphosphate; Uridine Diphosphate N-Acetylgalactosamine | 2002 |
Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Chenopodium album; Enzyme Inhibitors; Histidine; Hydrolysis; Isoflurophate; Lipase; Molecular Sequence Data; Morpholines; Mutagenesis, Site-Directed; Mutation; p-Chloromercuribenzoic Acid; Phenylmethylsulfonyl Fluoride; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases | 2003 |
Rat NTE-related esterase is a membrane-associated protein, hydrolyzes phenyl valerate, and interacts with diisopropylfluorophosphate through a serine catalytic machinery.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carboxylic Ester Hydrolases; Cells, Cultured; Cloning, Molecular; Female; Gene Expression Regulation, Enzymologic; Humans; Hydrolysis; Isoflurophate; Kidney; Male; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Organ Specificity; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serine; Species Specificity; Tissue Distribution; Transfection; Valerates | 2003 |
Serine phosphoric acid from diisopropylphosphoryl chymotrypsin.
Topics: Chymotrypsin; Endopeptidases; Hydrolases; Isoflurophate; Peptide Hydrolases; Phosphoric Acids; Serine | 1953 |
Serine phosphoric acid from diisopropylphosphoryl derivative of eel cholinesterase.
Topics: Animals; Cholinesterases; Eels; Isoflurophate; Phosphoric Acids; Serine | 1954 |
Isolation of serine phosphate from the active site of human prostatic acid phosphatase; inhibition of the enzyme by DFP.
Topics: Acid Phosphatase; Catalytic Domain; Humans; Isoflurophate; Male; Phosphoric Monoester Hydrolases; Phosphoserine; Prostate; Protein Tyrosine Phosphatases; Serine | 1962 |
Isolation of radioactive phosphorylserine from different rat-liver cell fractions incubated with P-labelled di-isopropyl phosphorofluoridate.
Topics: Animals; Isoflurophate; Liver; Phosphoserine; Rats; Serine | 1962 |
INHIBITION BY DIISOPROPYLFLUOROPHOSPHATE OF A KIDNEY TRANSPORT ADENOSINE TRIPHOSPHATASE BY PHOSPHORYLATION OF A SERINE RESIDUE.
Topics: Adenosine Triphosphatases; Biological Transport; Calcium; Cell Membrane Permeability; Diphosphates; Ions; Isoflurophate; Kidney; Magnesium; Nucleosides; Nucleotides; Ouabain; Pharmacology; Phosphorylation; Potassium; Research; Serine; Sodium; Sodium, Dietary; Strophanthins | 1964 |
Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry.
Topics: Animals; Catalysis; Humans; Hydrogen-Ion Concentration; Immunodominant Epitopes; Isoflurophate; Lipids; Mice; Molecular Mimicry; Multiple Sclerosis; Myelin Basic Protein; Peptide Fragments; Protease Inhibitors; Recombinant Proteins; Serine; Temperature | 2005 |
Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide.
Topics: Acyltransferases; Amyloid beta-Peptides; Animals; Autoradiography; Cell Line; Chlorocebus aethiops; Cholinesterase Inhibitors; Culture Media, Conditioned; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Isoflurophate; Mutation; Neuroblastoma; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Tandem Mass Spectrometry; Transfection; Tritium | 2007 |
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
Topics: Butyrylcholinesterase; Catalytic Domain; Chemical Warfare Agents; Cholinesterase Inhibitors; Deuterium Oxide; Dichlorvos; Echothiophate Iodide; Enzyme Stability; Humans; Insecticides; Isoflurophate; Malathion; Molecular Structure; Peptide Mapping; Sarin; Serine; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin | 2007 |
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
Topics: Albumins; Biotin; Chlorpyrifos; Chromatography, Liquid; Crystallography, X-Ray; Dichlorvos; Humans; Hydrogen-Ion Concentration; Isoflurophate; Models, Molecular; Molecular Structure; Organophosphorus Compounds; Reproducibility of Results; Sarin; Serine; Soman; Staining and Labeling; Tandem Mass Spectrometry; Tyrosine | 2008 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |